Digital Commons Network^™

Global Technology Initiative At San Jose State University: Results Of Seven Years Of An International Experience For Students, Belle Wei, Patricia Backer, Wenchiang Chung, Andrew Wood

Faculty Publications

For XXX students to thrive in the highly competitive global economy, it is critical to develop international perspectives and knowledge. The $1 million Global Technology Initiative (GTI), established in 2004, provides SJSU students with an opportunity to gain a global perspective of the world by learning about technology and business developments in the Asia Pacific region. GTI donors are high-tech business leaders with strong business ties in Silicon Valley and the Asia Pacific region. Given the current trend of engineering globalization in the global economy, particularly the trend of outsourcing Silicon Valley manufacturing, development, and design work to foreign countries, …

Accelerometry Cut Points For Physical Activity In Underserved African Americans, Nevelyn N. Trumpeter, Hannah G. Lawman, Dawn K. Wilson, Russell R. Pate, M. Lee Van Horn, Alicia K. Tate

Faculty Publications

Background: Despite their increased use, no studies have examined the validity of Actical accelerometry cut points for moderate physical activity (PA) in underserved (low-income, high-crime), minority populations. The high rates of chronic disease and physical inactivity in these populations likely impact the measurement of PA. There is growing concern that traditionally defined cut points may be too high for older or inactive adults. The present study aimed to determine the self-selected pace associated with instructions to "walk for exercise" and the corresponding accelerometry estimates (e.g. Actical counts/minute) for underserved, African American adults.

Method: Fifty one participants (61% women) had a …

Exploring Post-Translational Arginine Modification Using Chemically Synthesized Methylglyoxal Hydroimidazolones, Tina Wang, Rendy Kartika, David A. Spiegel

Faculty Publications

The methylglyoxal-derived hydroimidazolones (MG-Hs) comprise the most prevalent class of non-enzymatic, post-translational modifications of protein arginine residues found in nature. These adducts form spontaneously in the human body, and are also present at high levels in the human diet. Despite numerous lines of evidence suggesting that MG-H-arginine adducts play critical roles in both healthy and disease physiology in humans, detailed studies of these molecules have been hindered by a lack of general synthetic strategies for their preparation in chemically homogeneous form, and on scales sufficient to enable detailed biochemical and cellular investigations. To address this limitation, we have developed efficient, …

On Vacation With God: A Guide To Spiritual And Physical Renewal, Gerald A. Klingbeil

Faculty Publications

No abstract provided.

Accountability As Cultural Keyword, Melvin J. Dubnick

Faculty Publications

This paper examines “accountability” as a cultural phenomenon, and specifically as what Raymond Williams termed a “cultural keyword.” Williams designates as keywords those terms in a community’s vocabulary that not only provide meaningful insights into the priorities and values of that society, but also play a significant role in creating the dynamic cultural milieu that connects and shapes important and problematic social arenas. After positing that accountability has achieved cultural keyword status, I explore the term as a word, concept and speech act. (This is revision dated 5/23/2012.)

New Technology - Old Law: Autonomous Vehicles And California's Insurance Framework, Robert Peterson

Faculty Publications

In 1988 California voters adopted Proposition 103. The Proposition moved California into the group of states that regulates and requires prior approval of all automotive rates. Had it done only this, insuring autonomous vehicles would present only modest challenges.

Proposition 103, however, did much more. It entrenched into California insurance law a number of requirements that are incompatible with autonomous vehicles and the rapidly advancing technology they embody. The Proposition mandates the use of some specific rating factors that determine a vehicle owner’s premium. This rating system makes little sense when applied to self-driving vehicles. The Proposition also mandates a …

The African Cichlid Fish Astatotilapia Burtoni Uses Acoustic Communication For Reproduction: Sound Production, Hearing, And Behavioral Significance, Karen P. Maruska, Uyhun S. Ung, Russell D. Fernald

Faculty Publications

Sexual reproduction in all animals depends on effective communication between signalers and receivers. Many fish species, especially the African cichlids, are well known for their bright coloration and the importance of visual signaling during courtship and mate choice, but little is known about what role acoustic communication plays during mating and how it contributes to sexual selection in this phenotypically diverse group of vertebrates. Here we examined acoustic communication during reproduction in the social cichlid fish, Astatotilapia burtoni. We characterized the sounds and associated behaviors produced by dominant males during courtship, tested for differences in hearing ability associated with female …

Adrenergic Alpha-1 Pathway Is Associated With Hypertension Among Nigerians In A Pathway-Focused Analysis, Nicholas P. Reder, Bamidele O. Tayo, Babatunde Salako, Adesola Ogunniyi, Adebowale Adeyemo, Charles Rotimi, Richard S. Cooper

Faculty Publications

Background: The pathway-focused association approach offers a hypothesis driven alternative to the agnostic genome-wide association study. Here we apply the pathway-focused approach to an association study of hypertension, systolic blood pressure (SBP), and diastolic blood pressure (DBP) in 1614 Nigerians with genome-wide data. Methods and Results: Testing of 28 pathways with biological relevance to hypertension, selected a priori, containing a total of 101 unique genes and 4,349 unique single-nucleotide polymorphisms (SNPs) showed an association for the adrenergic alpha 1 (ADRA1) receptor pathway with hypertension (pp>10-5) SNPs offers a novel method for detecting the "missing heritability" of hypertension. These findings …

Walls Of Salvation, Hyveth Williams

Faculty Publications

No abstract provided.

Emergency Nurses' Perception Of Department Design As An Obstacle To Providing End-Of-Life Care, Renea L. Beckstrand, Ryan J. Rasmussen, Karlen E. (Beth) Luthy, Sondra Heaston

Faculty Publications

Introduction: Of the 119.2 million visits to the emergency department in 2006, it was estimated that about 249,000 visits resulted in the patient dying or being pronounced dead on arrival. In 2 national studies of emergency nurses' perceptions of end-of-life (EOL) care, ED design was identified as a large and frequent obstacle to providing EOL care. The purpose of this study was to determine the impact of ED design on EOL care as perceived by emergency nurses and to determine how much input emergency nurses have on the design of their emergency department.

Methods: A 25-item questionnaire regarding ED …

Szilard Engine Reversibility As Quantum Gate Function, F. Matthew Mihelic

Faculty Publications

A quantum gate is a logically and thermodynamically reversible situation that effects a unitary transformation of qubits of superimposed information, and essentially constitutes a situation for a reversible quantum decision. A quantum decision is a symmetry break, and the effect of the function of a Szilard engine is a symmetry break. A quantum gate is a situation in which a reversible quantum decision can be made, and so if a logically and thermodynamically reversible Szilard engine can be theoretically constructed then it would function as a quantum gate. While the traditionally theorized Szilard engine is not thermodynamically reversible, if one …

Healthy Aging And Older Asian Indian Immigrants: A Key Informant Survey Of Seven Ethnic Community Centers In Santa Clara County, Sadhna Diwan, Sharvari Dixit

Faculty Publications

This study is an examination of the present status of healthy aging programs and services provided to older Asian Indian (AI) immigrants in Santa Clara County. The primary goals of the study were to develop a profile of programs being offered to AI seniors at various ethnic community organizations; and to determine the met and unmet needs for programs and services that promote healthy aging in the AI senior population. A key informant survey was conducted with leaders of seven different organizations in Santa Clara County known to currently provide some services to AI seniors. These seven organizations are estimated …

Differences In Substance-Related Risk Behavior Between Dual And Triple Diagnosed Severely Mentally Ill Adults, Michelle Hampton, Linda Chafetz, Carmen Portillo

Faculty Publications

No abstract provided.

The Future Workforce In Cancer Prevention: Advancing Discovery, Research, And Technology, Wayne D. Newhauser, Michael E. Scheurer, Jessica M. Faupel-Badger, Jessica Clague, Jeffrey Weitzel, Kendra V. Woods

Faculty Publications

As part of a 2-day conference on October 15 and 16, 2009, a nine-member task force composed of scientists, clinicians, educators, administrators, and students from across the USA was formed to discuss research, discovery, and technology obstacles to progress in cancer prevention and control, specifically those related to the cancer prevention workforce. This article summarizes the task force's findings on the current state of the cancer prevention workforce in this area and its needs for the future. The task force identified two types of barriers impeding the current cancer prevention workforce in research, discovery, and technology from reaching its fullest …

Reno: Regularized Non-Parametric Analysis Of Protein Lysate Array Data, Bin Li, Feng Liang, Jianhua Hu, Xuming He

Faculty Publications

Motivation: The reverse-phase protein lysate arrays have been used to quantify the relative expression levels of a protein in a number of cellular samples simultaneously. To avoid quantification bias due to mis-specification of commonly used parametric models, a nonparametric approach based on monotone response curves may be used. The existing methods, however, aggregate the protein concentration levels of replicates of each sample, and therefore fail to account for within-sample variability. Results: We propose a method of regularization on protein concentration estimation at the level of individual dilution series to account for within-sample or within-group variability. We use an efficient algorithm …

Patterns Of Sodium And Potassium Excretion And Blood Pressure In The African Diaspora, B. O. Tayo, A. Luke, C. A. Mckenzie, H. Kramer, G. Cao, R. Durazo-Arvizu, T. Forrester, A. A. Adeyemo, R. S. Cooper

Faculty Publications

Habitual levels of dietary sodium and potassium are correlated with age-related increases in blood pressure (BP) and likely have a role in this phenomenon. Although extensive published evidence exists from randomized trials, relatively few large-scale community surveys with multiple 24-h urine collections have been reported. We obtained three 24-h samples from 2704 individuals from Nigeria, Jamaica and the United States to evaluate patterns of intake and within-person relationships with BP. The average (±s.d.) age and weight of the participants across all the three sites were 39.9±8.6 years and 76.1±21.2 kg, respectively, and 55% of the total participants were females. Sodium …

Enhanced Salt Stress Tolerance Of Rice Plants Expressing A Vacuolar H +-Atpase Subunit C1 (Savhac1) Gene From The Halophyte Grass Spartina Alterniflora Löisel, Niranjan Baisakh, Mangu V. Ramanarao, Kanniah Rajasekaran, Prasanta Subudhi, Jaroslav Janda, David Galbraith, Cheryl Vanier, Andy Pereira

Faculty Publications

The physiological role of a vacuolar ATPase subunit c1 (SaVHAc1) from a halophyte grass Spartina alterniflora was studied through its expression in rice. The SaVHAc1-expressing plants showed enhanced tolerance to salt stress than the wild-type plants, mainly through adjustments in early stage and preparatory physiological responses. In addition to the increased accumulation of its own transcript, SaVHAc1 expression led to increased accumulation of messages of other native genes in rice, especially those involved in cation transport and ABA signalling. The SaVHAc1-expressing plants maintained higher relative water content under salt stress through early stage closure of the leaf stoma and reduced …

Control Of Aperture Closure Initiation During Trunk-Assisted Reach-To-Grasp Movements, Miya K. Rand, Arend W.A. Van Gemmert, Abul B.M.I. Hossain, Yury P. Shimansky, George E. Stelmach

Faculty Publications

The present study investigated how the involvement and direction of trunk movement during reach-to-grasp movements affect the coordination between the transport and grasping components. Seated young adults made prehensile movements in which the involvement of the trunk was varied; the trunk was not involved, moved forward (flexion), or moved backward (extension) in the sagittal plane during the reach to the object. Each of the trunk movements was combined with an extension or flexion motion of the arm during the reach. Regarding the relationship between the trunk and arm motion for arm transport, the onset of wrist motion relative to that …

The Cortisol Awakening Response (Car) In 2-To 4-Year-Old Children: Effects Of Acute Nighttime Sleep Restriction, Wake Time, And Daytime Napping, Colleen E. Gribbin, Sarah Enos Watamura, Alyssa Cairns, John R. Harsh, Monique K. Lebourgeois

Faculty Publications

The cortisol awakening response (CAR) is presumed critically important for healthy adaptation. The current literature, however, is hampered by systematic measurement difficulties relative to awakening, especially with young children. While reports suggest the CAR is smaller in children than adults, well-controlled research in early childhood is scarce. We examined whether robust CARs exist in 2- to 4-year-old children and if sleep restriction, wake timing, and napping influence the CAR (n?=?7). During a 25-day in-home protocol, researchers collected four salivary cortisol samples (0, 15, 30, 45?min post-wake) following five polysomnographic sleep recordings on nonconsecutive days after 4?hr (morning nap), 7?hr (afternoon …

The Nation Before Taste: The Challenges Of American Culinary History, Andrew P. Haley

Faculty Publications

Food is material and familiar, and because it is, we are often overconfident about our ability to understand the culinary past. It is easy to believe that if we can discover the recipe for some forgotten dish, the history of the dish becomes intelligible. When it does not, it tempts those who consume culinary history to impose modern sensibilities on our predecessors. The Nation before Taste" argues that historians and museum curators must be especially vigilant when presenting the history of food. Reviewing a series of historical challenges that stemmed from studying the United States in the late nineteenth and …

A School-Based, Peer Leadership Physical Activity Intervention For 6th Graders: Feasibility And Results Of A Pilot Study, Daheia J. Barr-Anderson, Melissa N. Laska, Sara Veblen-Mortenson, Kian Farbakhsh, Bonnie Dudovitz, Mary Story

Faculty Publications

Background: The aim of this study was to promote physical activity in 6th graders by developing and testing the feasibility of an enhanced Presidential Active Lifestyle Award (PALA) program comprised of a peer leadership component and innovative exercise resource toolkit including DVDs. Methods: A racially/ethnically diverse sample of students received the standard PALA program (2 control schools, n = 61) or enhanced PALA+Peers program (2 intervention schools, n = 87) during 2006-2007 academic year. Results: Compared with the control condition, the intervention was successful in increasing moderate physical activity in all students (P = .02) and …

Adverse Metabolic Response To Regular Exercise: Is It A Rare Or Common Occurrence?, Claude Bouchard, Steven N. Blair, Timothy S. Church, Conrad P. Earnest, James M. Hagberg, Keijo Häkkinen, Nathan T. Jenkins, Laura Karavirta, William E. Kraus, Dabeeru C. Rao, Mark A. Sarzynski, James S. Skinner, Cris A. Slentz, Tuomo Rankinen

Faculty Publications

Background: Individuals differ in the response to regular exercise. Whether there are people who experience adverse changes in cardiovascular and diabetes risk factors has never been addressed.

Methodology/Principle Findings: An adverse response is defined as an exercise-induced change that worsens a risk factor beyond measurement error and expected day-to-day variation. Sixty subjects were measured three times over a period of three weeks, and variation in resting systolic blood pressure (SBP) and in fasting plasma HDL-cholesterol (HDL-C), triglycerides (TG), in insulin (FI) was quantified. The technical error (TE) defined as the within-subject standard deviation derived from these measurements was computed. An …

Iraq And Afghanistan Veterans’ Experiences Living With Their Parents After Separation From The Military, Miranda E. Worthen, M Moos, R Ahem

Faculty Publications

When military service members separate from the military, many return to their families of origin, living with their parents for a period of several weeks to years. While research with veterans and their spouses has documented the particular strain of this reintegration period on veterans and their partners, little research to date has examined veterans’ experiences living with their parents. The present study sought to fill this research gap by investigating veterans’ experiences living with their parents using qualitative, in-depth interviews with Iraq and Afghanistan veterans in California. Overall, veterans appreciated the instrumental and emotional support their parents provided when …

Regulatory And Judicial Implementations Of Patent Law Flexibilities, Sarah R. Wasserman Rajec

Faculty Publications

No abstract provided.

Italy At Home And Abroad After 150 Years: The Legacy Of Emigration And The Future Of Italianità, Mark I. Choate

Faculty Publications

Shortly after unification in the Risorgimento, mass emigration stretched Italy in unforeseen ways, changing its culture, economics, and politics, and even its state, territory, language, and population. This enforced globalization polarized Italy and radically changed Italy as a nation-state and as a national culture. Controversies over emigration sharply divided Italian Liberals from the Nationalists and Fascists. The ideals of the nation-state, articulated by Mazzini, have been transformed by emigration in ways that have anticipated the twenty-first century global world. Today Italy faces similar challenges with rising immigration, together with the potential for constructive solutions.

Interest-Balancing Vs. Fiduciary Duty: Two Models For National Security Law, Evan Fox-Decent, Evan J. Criddle

Faculty Publications

No abstract provided.

A Two-Stage Cluster Sampling Method Using Gridded Population Data, A Gis, And Google Earth(Tm) Imagery In A Population-Based Mortality Survey In Iraq, Lp Galway, Nathaniel Bell, Al Shatari Sae, Amy Hagopian, Gilbert Burnham, Abraham Flaxman, Wiliam M. Weiss, Julie Rajaratnam, Tim K. Takaro

Faculty Publications

BACKGROUND:

Mortality estimates can measure and monitor the impacts of conflict on a population, guide humanitarian efforts, and help to better understand the public health impacts of conflict. Vital statistics registration and surveillance systems are rarely functional in conflict settings, posing a challenge of estimating mortality using retrospective population-based surveys.

RESULTS:

We present a two-stage cluster sampling method for application in population-based mortality surveys. The sampling method utilizes gridded population data and a geographic information system (GIS) to select clusters in the first sampling stage and Google Earth TM imagery and sampling grids to select households in the second sampling …

Phthalocyanine-Peptide Conjugates For Epidermal Growth Factor Receptor Targeting, Benson G. Ongarora, Krystal R. Fontenot, Xiaoke Hu, Inder Sehgal, Seetharama D. Satyanarayana-Jois, Dm Graça H. Vicente

Faculty Publications

Four phthalocyanine (Pc)-peptide conjugates designed to target the epidermal growth factor receptor (EGFR) were synthesized and evaluated in vitro using four cell lines: human carcinoma A431 and HEp2, human colorectal HT-29, and kidney Vero (negative control) cells. Two peptide ligands for EGFR were investigated: EGFR-L1 and -L2, bearing 6 and 13 amino acid residues, respectively. The peptides and Pc-conjugates were shown to bind to EGFR using both theoretical (Autodock) and experimental (SPR) investigations. The Pc-EGFR-L1 conjugates 5a and 5b efficiently targeted EGFR and were internalized, in part due to their cationic charge, whereas the uncharged Pc-EGFR-L2 conjugates 4b and 6a …

Sustainability: More About The Toolmaker Than The Tools, R. Eugene Turner

Faculty Publications

A sustainable system is not necessarily a high-quality one, but it could be. We could, for example, “survive” on the desperate edge, as the remnants in a self-fouled and deteriorating environment. Why won’t a future sustainable system be just another industrial model of mass efficiency and throughput? Perhaps the incompatible outcomes are a choice between the sometimes nearly invisible civilizing aspects of culture nurturing respect, equality, and cooperation on one hand, and the greed and self-indulgences undermining social tolerance, empathy, and cooperation that ends up promoting violence and dehumanization. The human heritage is subtle, indestructible, and worth nurturing if we …

Evaluation Of Methods To Relieve Parental Perceptions Of Vaccine-Associated Pain And Anxiety In Children: A Pilot Study, Karlen E. (Beth) Luthy, Renea L. Beckstrand, Amy Pulsipher

Faculty Publications

Introduction: The pain and anxiety associated with vaccination is a significant reason why parents are reluctant to have their children vaccinated. Distraction methods and vapocoolant sprays may be use to modify the parent's perceptions of their child's pain and anxiety, thus encouraging parents to return for the child's next vaccination.

Methods: A convenience sample of 68 parents with children ranging in age from 2 to 12 years was selected. The parents and the child were randomly assigned to three groups: a control group, a DVD distraction group, or a vapocoolant spray group. After the child was vaccinated, parents evaluated the …