Digital Commons Network^™

Stepfamily Functioning And Closeness: Children's Views On Second Marriages And Stepfather Relationships, Todd M. Jensen, Kevin Shafer

Faculty Publications

Current research on stepfamily well-being often overlooks the perspective of children, and deals primarily with factors as reported by the adults involved. The authors examine a number of family role characteristics, parental subsystem characteristics, and resources that might influence how children perceive the quality of their stepfamily relationships. A sample of 1,088 children in households with a mother and stepfather, ages 10 to 16 years, in the National Longitudinal Survey of Youth, 1979 cohort—Children and Young Adult Sample, is used for the analyses. Results indicate that open communication between children and their mothers, low amounts of arguing between mothers and …

Corpse Management In Social Insects, Qian Sun, Xuguo Zhou

Faculty Publications

Undertaking behavior is an essential adaptation to social life that is critical for colony hygiene in enclosed nests. Social insects dispose of dead individuals in various fashions to prevent further contact between corpses and living members in a colony. Focusing on three groups of eusocial insects (bees, ants, and termites) in two phylogenetically distant orders (Hymenoptera and Isoptera), we review mechanisms of death recognition, convergent and divergent behavioral re-sponses toward dead individuals, and undertaking task allocation from the perspective of division of labor. Distinctly different solutions (e.g., corpse removal, burial and cannibalism) have evolved, independently, in the holometabolous hymenopterans and …

Snp Discovery And Chromosome Anchoring Provide The First Physically-Anchored Hexaploid Oat Map And Reveal Synteny With Model Species, Rebekah E. Oliver, Nicholas A. Tinker, Gerard R. Lazo, Shiaoman Chao, Eric N. Jellen, Martin L. Carson, Howard W. Rines, Donald E. Obert, Joseph D. Lutz, Irene Shackelford, Abraham B. Korol, Charlene P. Wight, Kyle M. Gardner, Jiro Hattori, Aaron D. Beattie, Åsmund Bjørnstad, J. Michael Bonman, Jean Luc Jannink, Mark E. Sorrells, Gina L. Brown-Guedira, Jennifer W. Mitchell Fetch, Stephen A. Harrison, Catherine J. Howarth, Amir Ibrahim, Frederic L. Kolb, Michael S. Mcmullen, J. Paul Murphy, Herbert W. Ohm, Brian G. Rossnagel, Weikai Yan, Kelci J. Miclaus, Jordan Hiller, Peter J. Maughan

Faculty Publications

A physically anchored consensus map is foundational to modern genomics research; however, construction of such a map in oat (Avena sativa L., 2n = 6x = 42) has been hindered by the size and complexity of the genome, the scarcity of robust molecular markers, and the lack of aneuploid stocks. Resources developed in this study include a modified SNP discovery method for complex genomes, a diverse set of oat SNP markers, and a novel chromosome-deficient SNP anchoring strategy. These resources were applied to build the first complete, physically-anchored consensus map of hexaploid oat. Approximately 11,000 high-confidence in silico SNPs were …

Overweight And Obesity In Kaoma And Kasama Rural Districts Of Zambia: Prevalence And Correlates In 2008-2009 Population Based Surveys, Chola Besa, David Mulenga, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula, Emmanuel Rudatsikira, Seter Siziya

Faculty Publications

Background: Overweight and obesity (overweight/obesity) is associated with hypertension. Low- and middleincome countries are experiencing an obesity epidemic. There is growing evidence that the epidemic is on the increase in urban settings of developing countries. However, there is scanty information on the magnitude of this epidemic and its correlates in rural settings. The objective of the current study was to establish levels of overweight/obesity and its correlates in rural areas of Zambia. Designing interventions based on the correlates for overweight/obesity to reduce its prevalence may in turn lead to a reduction in the prevalence of hypertension.

Methods: Cross sectional studies …

Effect Of Cd44 Binding Peptide Conjugated To An Engineered Inert Matrix On Maintenance Of Breast Cancer Stem Cells And Tumorsphere Formation, Xiaoming Yang, Samaneh Kamali Sarvestani, Seyedsina Moeinzadeh, Xuezhong He, Esmaiel Jabbari

Faculty Publications

Introduction: As cancer cells are affected by many factors in their microenvironment, a major challenge is to isolate the effect of a specific factor on cancer stem cells (CSCs) while keeping other factors unchanged. We have developed a synthetic inert 3D polyethylene glycol diacrylate (PEGDA) gel culture system as a unique tool to study the effect of microenvironmental factors on CSCs response. We have reported that CSCs formed in the inert PEGDA gel by encapsulation of breast cancer cells maintain their stemness within a certain range of gel stiffness. The objective was to investigate the effect of CD44 binding peptide …

H3k4 Methyltransferase Set1 Is Involved In Maintenance Of Ergosterol Homeostasis And Resistance To Brefeldin A, Paul F. South, Kayla M. Harmeyer, Nina D. Serratore, Scott D. Briggs

Faculty Publications

Set1 is a conserved histone H3 lysine 4 (H3K4) methyltransferase that exists as a multisubunit complex. Although H3K4 methylation is located on many actively transcribed genes, few studies have established a direct connection showing that loss of Set1 and H3K4 methylation results in a phenotype caused by disruption of gene expression. In this study, we determined that cells lacking Set1 or Set1 complex members that disrupt H3K4 methylation have a growth defect when grown in the presence of the antifungal drug Brefeldin A (BFA), indicating that H3K4 methylation is needed for BFA resistance. To determine the role of Set1 in …

Iron Binding Activity Is Essential For The Function Of Isca In Iron-Sulphur Cluster Biogenesis, Aaron P. Landry, Zishuo Cheng, Huangen Ding

Faculty Publications

Iron-sulphur cluster biogenesis requires coordinated delivery of iron and sulphur to scaffold proteins, followed by transfer of the assembled clusters from scaffold proteins to target proteins. This complex process is accomplished by a group of dedicated iron-sulphur cluster assembly proteins that are conserved from bacteria to humans. While sulphur in iron-sulphur clusters is provided by l-cysteine via cysteine desulfurase, the iron donor(s) for iron-sulphur cluster assembly remains largely elusive. Here we report that among the primary iron-sulphur cluster assembly proteins, IscA has a unique and strong binding activity for mononuclear iron in vitro and in vivo. Furthermore, the ferric iron …

Planning And Adjustments For The Control Of Reach Extent In A Virtual Environment, Jill Campbell Stewart Pt,Phd, James Gordon, Carolee J. Winstein

Faculty Publications

Background Skilled performance of reach actions includes both anticipatory planning and compensatory adjustments made while moving. The execution of reach actions in a virtual environment (VE) demonstrates similar characteristics to reaches performed in the real-world, however, it is unclear whether the VE itself significantly impacts movement planning or compensatory adjustments. The purpose of this study was to directly compare the use of planning and adjustments to control extent for unconstrained reach actions performed in an immersive VE to those performed in an analogous real-world environment (RWE). Methods Five non-disabled adults (29 ± 5 years) reached with the dominant, right arm …

Optical Dissection Of Odor Information Processing In Vivo Using Gcamps Expressed In Specified Cell Types Of The Olfactory Bulb., Wachowiak M, Economo Mn, Díaz-Quesada M, Brunert D, Wesson Dw, White Ja, Rothermel M

Faculty Publications

No abstract provided.

Non-Market Values In Family Businesses, Benjamin Means

Faculty Publications

Despite the economic importance of family businesses, legal scholarship has often overlooked their distinctive character. Instead, scholars focus on the chosen form of business organization — partnership, corporation, LLC — and assume that the participants are economically rational actors who seek to maximize their individual preferences. This Article contends that family businesses are an extension of family relationships and that non-market values affect their goals and governance choices.

Just as family law scholars have shown that contract principles can be applied to regulate intimate relationships, corporate law scholars should recognize that the intimacy of family life often substitutes for arms-length …

Snapshot Of The Equilibrium Dynamics Of A Drug Bound To Hiv-1 Reverse Transcriptase, Daniel G. Kuroda, Joseph D. Bauman, J. Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Eddy Arnold, Robin M. Hochstrasser

Faculty Publications

The anti-AIDS drug rilpivirine undergoes conformational changes to bind HIV-1 reverse transcriptase (RT), which is an essential enzyme for the replication of HIV. These changes allow it to retain potency against mutations that otherwise would render the enzyme resistant. Here we report that water molecules play an essential role in this binding process. Femtosecond experiments and theory expose the molecular level dynamics of rilpivirine bound to HIV-1 RT. Two nitrile substituents, one on each arm of the drug, are used as vibrational probes of the structural dynamics within the binding pocket. Two-dimensional vibrational echo spectroscopy reveals that one nitrile group …

The Amino Terminus Of Herpes Simplex Virus 1 Glycoprotein K Is Required For Virion Entry Via The Paired Immunoglobulin-Like Type-2 Receptor Alpha, Sona Chowdhury, Vladimir N. Chouljenko, Misagh Naderi, Konstantin G. Kousoulas

Faculty Publications

The herpes simplex virus 1 (HSV-1) glycoprotein K (gK)/UL20 protein complex is incorporated into virion envelopes and cellular membranes and functions during virus entry and cell-to-cell spread. To investigate the role of gK/UL20 in the context of a highly neurovirulent virus strain, the HSV-1(McKrae) genome was cloned into a bacterial artificial chromosome plasmid (McKbac) and utilized to construct the mutant virus McK(gKδ31-68), carrying a 37-amino-acid deletion within the gK amino terminus. The McKbac virus entered efficiently into Chinese hamster ovary (CHO) cells constitutively expressing HSV-1 human receptors, nectin-1, herpesvirus entry mediator (HVEM), or paired immunoglobulin-like type-2 receptor alpha (PILRα). In …

Vitronectin Inhibits Efferocytosis Through Interactions With Apoptotic Cells As Well As With Macrophages, Hong Beom Bae, Jean Marc Tadie, Shaoning Jiang, Dae Won Park, Celeste P. Bell, Lawrence C. Thompson, Cynthia B. Peterson, Victor J. Thannickal, Edward Abraham, Jaroslaw W. Zmijewski

Faculty Publications

Effective removal of apoptotic cells, particularly apoptotic neutrophils, is essential for the successful resolution of acute inflammatory conditions. In these experiments, we found that whereas interaction between vitronectin and integrins diminished the ability of macrophages to ingest apoptotic cells, interaction between vitronectin with urokinase-type plasminogen activator receptor (uPAR) on the surface of apoptotic cells also had equally important inhibitory effects on efferocytosis. Preincubation of vitronectin with plasminogen activator inhibitor-1 eliminated its ability to inhibit phagocytosis of apoptotic cells. Similarly, incubation of apoptotic cells with soluble uPAR or Abs to uPAR significantly diminished efferocytosis. In the setting of LPSinduced ALI, enhanced …

A 5-Day Method For Determination Of Soluble Silicon Concentrations In Nonliquid Fertilizer Materials Using A Sodium Carbonate-Ammonium Nitrate Extractant Followed By Visible Spectroscopy With Heteropoly Blue Analysis: Single-Laboratory Validation, Dennis Sebastian, Hugh Rodrigues, Charles Kinsey, Gaspar Korndörfer, Hamilton Pereira, Guilherme Buck, Lawrence Datnoff, Stephen Miranda, Mary Provance-Bowley

Faculty Publications

A 5-day method for determining the soluble silicon (Si) concentrations in nonliquid fertilizer products was developed using a sodium carbonate (Na 2CO3)-ammonium nitrate (NH4NO3) extractant followed by visible spectroscopy with heteropoly blue analysis at 660 nm. The 5-Day Na2CO3-NH4NO3 Soluble Si Extraction Method can be applied to quantify the plant-available Si in solid fertilizer products at levels ranging from 0.2 to 8.4% Si with an LOD of 0.06%, and LOQ of 0.20%. This Si extraction method for fertilizers correlates well with plant uptake of Si (r2 = 0.96 for a range of solid fertilizers) and is applicable to solid Si …

Evidence Of Establishment Of Bagous Hydrillae (Coleoptera: Curculionidae), A Biological Control Agent Of Hydrilla Verticillata (Hydrocharitales: Hydrocharitaceae) In North America?, Ted D. Center, Katherine Parys, Mike Grodowitz, Gregory S. Wheeler, F. Allen Dray, Charles W. O'Brien, Seth Johnson, Al Cofrancesco

Faculty Publications

The semi-aquatic weevil Bagous hydrillae was released during 1991-1996 at 19 sites in 4 states in attempts to control the aquatic weed hydrilla, Hydrilla verticillata. Fourteen of the sites were in Florida, 2 each in Texas and Georgia and one site in Alabama. Over 320,000 adult weevils were included in these releases. Despite the fact that a few adults were recovered as late as 4.5 yr post-release, presence of permanent, self-perpetuating populations was never confirmed. Then, during 2009 adult B. hydrillae were collected in southern Louisiana, at least 580 km from the nearest release site and 13 yr after attempts …

Biological Control Of Common Salvinia (Salvinia Minima) In Louisiana Using Cyrtobagous Salviniae (Coleoptera: Curculionidae), Katherine A. Parys, Seth J. Johnson

Faculty Publications

Common salvinia, Salvinia minima Baker, is an aquatic invasive fern that obstructs waterways and impacts water quality throughout the southeastern United States. In an effort to establish populations for classical biological control of this weed, the weevil, Cyrtobagous salviniae Calder and Sands, was released at multiple sites across Louisiana. Many of the release sites were lost due to a variety of ecological and anthropological disturbances. In 2008, C. salviniae was found to have successfully overwintered on S. minima in Gramercy, Louisiana. Attack by Cyrtobagous salviniae significantly increased the number of damaged terminal buds and decreased the fresh weight biomass of …

Family Bonding And Family Dinners, Duane C. Mcbride, D. Sedlacek, Alina Baltazar, L. Matthews, Romulus Chelbegean, Gary L. Hopkins

Faculty Publications

No abstract provided.

Science, Technology, And Catholic Identity In The Education Of Professionals, Keith Douglass Warner O.F.M., David S. Caudill

Faculty Publications

The reception of Ex corde ecclesiae has been uneven across the disciplines, with scant interest in distinctly Catholic pedagogies outside of the humanities. This essay argues that Catholic universities can distinguish themselves by how they present science and technology in their curriculum by drawing from the interdisciplinary field of “science, technology & society,” or STS. We argue that discussions about Catholic identity, science, and human values can and should extend into the curriculum while simultaneously safeguarding academic freedom, and that this can readily be done in professional schools, such as law and engineering. We outline the contributions that STS as …

Three-Dimensional Engineered Matrix To Study Cancer Stem Cells And Tumorsphere Formation: Effect Of Matrix Modulus, Xiaoming Yang, Samaneh Kamali Sarvestani, Seyedsina Moeinzadeh, Xuezhong He, Esmaiel Jabbari

Faculty Publications

Maintenance of cancer stem cells (CSCs) is regulated by the tumor microenvironment. Synthetic hydrogels provide the flexibility to design three-dimensional (3D) matrices to isolate and study individual factors in the tumor microenvironment. The objective of this work was to investigate the effect of matrix modulus on tumorsphere formation by breast cancer cells and maintenance of CSCs in an inert microenvironment without the interference of other factors. In that regard, 4T1 mouse breast cancer cells were encapsulated in inert polyethylene glycol diacrylate hydrogels and the effect of matrix modulus on tumorsphere formation and expression of CSC markers was investigated. The gel …

The Supreme Court's Theory Of Private Law, Nathan B. Oman, Jason M. Solomon

Faculty Publications

In this Article, we revisit the clash between private law and the First Amendment in the Supreme Court’s recent case, Snyder v. Phelps, using a private-law lens. We are scholars who write about private law as individual justice, a perspective that has been lost in recent years but is currently enjoying something of a revival.

Our argument is that the Supreme Court’s theory of private law has led it down a path that has distorted its doctrine in several areas, including the First Amendment–tort clash in Snyder. In areas that range from punitive damages to preemption, the Supreme Court has …

A Tutorial On Count Regression And Zero-Altered Count Models For Longitudinal Substance Use Data, Scott A. Baldwin, David C. Atkins, Cheng Zheng, Robert J. Gallop, Clayton Neighbors

Faculty Publications

Critical research questions in the study of addictive behaviors concern how these behaviors change over time - either as the result of intervention or in naturalistic settings. The combination of count outcomes that are often strongly skewed with many zeroes (e.g., days using, number of total drinks, number of drinking consequences) with repeated assessments (e.g., longitudinal follow-up after intervention or daily diary data) present challenges for data analyses. The current article provides a tutorial on methods for analyzing longitudinal substance use data, focusing on Poisson, zero-inflated, and hurdle mixed models, which are types of hierarchical or multilevel models. Two example …

Personal And Relationship Challenges Of Adults With Type 1 Diabetes, Paula M. Trief Phd, Jonathan G. Sandberg, Jacqueline A. Dimmock Phd, Patricia J. Forken Ba, Ruth S. Weinstock Md, Phd

Faculty Publications

Little is known about the psychosocial challenges of adults living with type 1 diabetes or its impact on partner relationships. This qualitative study was undertaken to gain better understanding of these issues.

Pastoral Stress Management To Maximize Family Function, H. Peter Swanson

Faculty Publications

No abstract provided.

Prevalence And Correlates Of Being Bullied Among In-School Adolescents In Malawi: Results From The 2009 Global School-Based Health Survey, H. W. Kubwalo, Adamson S. Muula, Seter Siziya, S. Pasupulati, Emmanuel Rudatsikira

Faculty Publications

Background

Physical and emotional violence against adolescents is a neglected, but growing problem globally. Violence against adolescents negatively affects the victim in terms of physical health, school attendance and performance and social adjustment. The literature on the prevalence and associated factors of bullying against adolescents is sparse in southern Africa outside South Africa. Such data are even sparser for Malawi. The current study was conducted to estimate the prevalence of self-reported bullying and its personal and social correlates.

Methods

A secondary analysis of the Malawi School-Based Student Health Survey (2009) was done. Descriptive analyses were done to describe the sample …

Oxidized Amino Acid Residues In The Vicinity Of QA And PheoD1 Of The Photosystem Ii Reaction Center: Putative Generation Sites Of Reducing-Side Reactive Oxygen Species, Laurie K. Frankel, Larry Sallans, Patrick A. Limbach, Terry M. Bricker

Faculty Publications

Under a variety of stress conditions, Photosystem II produces reactive oxygen species on both the reducing and oxidizing sides of the photosystem. A number of different sites including the Mn4O5Ca cluster, P680, PheoD1, QA, QB and cytochrome b559 have been hypothesized to produce reactive oxygen species in the photosystem. In this communication using Fourier-transform ion cyclotron resonance mass spectrometry we have identified several residues on the D1 and D2 proteins from spinach which are oxidatively modified and in close proximity to QA (D1 residues 239F, 241Q, 242E and the D2 residues 238P, 239T, 242E and 247M) and PheoD1 (D1 residues …

Blacks And Whites In The Cuba Have Equal Prevalence Of Hypertension: Confirmation From A New Population Survey, Pedro Ordúñez, Jay S. Kaufman, Mikhail Benet, Alain Morejon, Luis C. Silva, David A. Shoham, Richard S. Cooper

Faculty Publications

Background: The excess burden of hypertension among blacks has been a prominent feature of the heath disparities literature, and many scientists presume it to be a stable and inevitable phenomenon. The underlying causes of this disparity can only be disentangled in a setting in which the population does not experience racial stratification of socioeconomic opportunities. While such conditions of racial equality remain uncommon, they may be approximated in Cuba, a country with a persistent policy of social inclusion over the last 5 decades. Methods. We report on a 2010-2011 stratified probability sample of those aged 15-74 years from the urban …

Sexual Orientation Differences In The Relationship Between Victimization And Hazardous Drinking Among Women In The National Alcohol Survey, Laurie A. Drabble, K. F. Trocki, T. L. Hughes, R. A. Korcha, A. E. Lown

Faculty Publications

This study examined relationships between past experiences of victimization (sexual abuse and physical abuse in childhood, sexual abuse and physical abuse in adulthood, and lifetime victimization) and hazardous drinking among sexual minority women compared to exclusively heterosexual women. Data were from 11,169 women responding to sexual identity and sexual behavior questions from three National Alcohol Survey waves: 2000 (n = 3,880), 2005 (n = 3,464), and 2010 (n = 3,825). A hazardous drinking index was constructed from five dichotomous variables (5+ drinking in the past year, drinking two or more drinks daily, drinking to intoxication in the past year, two …

Comparison Of Risk Of Radiogenic Second Cancer Following Photon And Proton Craniospinal Irradiation For A Pediatric Medulloblastoma Patient, Rui Zhang, Rebecca M. Howell, Annelise Giebeler, Phillip J. Taddei, Anita Mahajan, Wayne D. Newhauser

Faculty Publications

Pediatric patients who received radiation therapy are at risk of developing side effects such as radiogenic second cancer. We compared proton and photon therapies in terms of the predicted risk of second cancers for a 4 year old medulloblastoma patient receiving craniospinal irradiation (CSI). Two CSI treatment plans with 23.4 Gy or Gy (RBE) prescribed dose were computed: a three-field 6 MV photon therapy plan and a four-field proton therapy plan. The primary doses for both plans were determined using a commercial treatment planning system. Stray radiation doses for proton therapy were determined from Monte Carlo simulations, and stray radiation …

An Extract Of Artemisia Dracunculus L. Inhibits Ubiquitin-Proteasome Activity And Preserves Skeletal Muscle Mass In A Murine Model Of Diabetes, Heather Kirk-Ballard, Zhong Q. Wang, Priyanka Acharya, Xian H. Zhang, Yongmei Yu, Gail Kilroy, David Ribnicky, William T. Cefalu, Z. Elizabeth Floyd

Faculty Publications

Impaired insulin signaling is a key feature of type 2 diabetes and is associated with increased ubiquitin-proteasome-dependent protein degradation in skeletal muscle. An extract of Artemisia dracunculus L. (termed PMI5011) improves insulin action by increasing insulin signaling in skeletal muscle. We sought to determine if the effect of PMI5011 on insulin signaling extends to regulation of the ubiquitin-proteasome system. C2C12 myotubes and the KK-Ay murine model of type 2 diabetes were used to evaluate the effect of PMI5011 on steady-state levels of ubiquitylation, proteasome activity and expression of Atrogin-1 and MuRF-1, muscle-specific ubiquitin ligases that are upregulated with impaired insulin …

Variation In Sodium Current Amplitude Between Vasopressin And Oxytocin Hypothalamic Supraoptic Neurons, Reese Scroggs, Lie Wang, Ryoichi Teruyama, William E. Armstrong

Faculty Publications

Biophysical characteristics of tetrodotoxin-sensitive sodium (Na+) currents were studied in vasopressin (VP) and oxytocin (OT) supraoptic neurons acutely isolated from rat hypothalamus. Na+ current density (pA/pF) was significantly greater in VP neurons than in OT neurons. No significant difference between VP and OT neurons was detected regarding the voltage dependence of activation and steady-state inactivation, or rate of recovery from inactivation of Na+ currents. In both VP and OT neurons, the macroscopic inactivation of the Na+ currents was best fitted with a double-exponential expression suggesting two rates of inactivation. Also in both types, the time course of recovery from inactivation …