Digital Commons Network^™

Ramipril Blunts Glycerol-Induced Acute Renal Failure In Rats Through Its Antiapoptosis, Anti-Inflammatory, Antioxidant, And Renin-Inhibiting Properties, Adeolu Alex Adedapo, Ehizogie Ruth Osaretin, Olufunke Olubunmi Falayi, Ademola Adetokunbo Oyagbemi, Blessing Seun Ogunpolu, Temidayo Olutayo Omobowale, Oluwafemi Omoniyi Oguntibeju, Momoh Audu Yakubu

Faculty Publications

Acute kidney injury (AKI) is a malady with a sudden onset resulting in buildup of waste matters in the body, but a specific cure hasn't been found as a lasting solution to AKI. In this study, ramipril was evaluated for its potential therapy in glycerol-induced AKI in rats. Twenty animals were divided into four groups of five animals each. Group I was the control while group II was given glycerol on day 8 only, groups III and IV were administered with pioglitazone (reference drug) and ramipril for seven days respectively and on day 8 received glycerol. On the ninth day, …

Health Research Capacity Building Of Health Workers In Fragile And Conflict-Affected Settings: A Scoping Review Of Challenges, Strengths, And Recommendations, Rania Mansour, Hady Naal, Tarek Kishawi, Nassim El Achi, Layal Hneiny, Shadi Saleh

Faculty Publications

Background

Fragile and conflict-affected settings (FCAS) have a strong need to improve the capacity of local health workers to conduct health research in order to improve health policy and health outcomes. Health research capacity building (HRCB) programmes are ideal to equip health workers with the needed skills and knowledge to design and lead health-related research initiatives. The study aimed to review the characteristics of HRCB studies in FCASs in order to identify their strengths and weaknesses, and to recommend future directions for the field.

Methods

We conducted a scoping review and searched four databases for peer-reviewed articles that reported an …

Reconsidering Section 1983'S Nonabrogation Of Sovereign Immunity, Katherine Mims Crocker

Faculty Publications

Motivated by civil unrest and the police conduct that prompted it, Americans have embarked on a major reexamination of how constitutional enforcement works. One important component is 42 U.S.C. § 1983, which allows civil suits against any "person" who violates federal rights. The U.S. Supreme Court has long held that "person" excludes states because Section 1983 flunks a condition of crystal clarity.

This Article reconsiders that conclusion--in legalese, Section 1983's nonabrogation of sovereign immunity--along multiple dimensions. Beginning with a negative critique, this Article argues that because the Court invented the crystal-clarity standard so long after Section 1983's enactment, the caselaw …

Delivering Bad News: Crisis Communication Methods In Academic Libraries, Brittany O'Neill, Rebecca Kelley

Faculty Publications

This exploratory study analyzed the specific crisis communication methods of academic libraries. A survey was sent to library staff at Association of Research Libraries-member colleges and universities to describe if, who, when, and how they communicated bad news to their stakeholders for major, minor, and emerging crises. The findings show that respondents used multiple communication strategies, which varied based on the crisis. The data show that libraries communicated journal and database cancellations and health and safety emergencies more slowly than access issues and were more likely not to communicate those crises at all. Respondents also more frequently chose to communicate …

On The Cusp Of The Next Medical Malpractice Insurance Crisis, Philip G. Peters Jr.

Faculty Publications

Medical malpractice claims are dwindling. Total payouts are far lower than during the 2002 crisis. Yet, insurance industry profits have been sinking for a decade and are nearly in the red. After a dozen years with a “soft” insurance market, we are now on the cusp of yet another malpractice insurance crisis.

How can profits be in peril if claims have dwindled and payouts are historically low?
Answering that question requires an understanding of the insurance cycle. The cycle periodically transforms gradual increases in costs and gradual decreases in revenue into explosive increases in premiums.

The industry’s financial statistics today …

Shakespeare In The Courts, Douglas E. Abrams

Faculty Publications

This article continues the theme of recent “Writing It Right” articles in the Journal of the Missouri Bar. These articles describe how federal and state judges today frequently accent their opinions’ substantive or procedural rulings with references to cultural markers that can resonate with the advocates, parties, and judges who comprise the opinions’ readership. The courts’ broad array of cultural references demonstrates versatility. Some of my early articles in the Journal profiled judicial opinions that referenced terminologies, rules, and traditions of baseball, football, and other sports. Together these sports’ mass audiences help define American culture.

Later my Journal articles profiled …

An Efficient Alternative To The Cdc Gravid Trap For Southern House Mosquito (Diptera: Culicidae) Surveillance, Timothy D. Mcnamara, Thomas A. O'Shea-Wheller, Nicholas Delisi, Emily Dugas, Kevin A. Caillouet, Randy Vaeth, Dennis Wallette, Kristen Healy

Faculty Publications

West Nile virus (WNV) is the most prevalent arbovirus found throughout the United States. Surveillance of surface breeding Culex vectors involved in WNV transmission is primarily conducted using CDC Gravid traps. However, anecdotal claims from mosquito abatement districts in Louisiana assert that other trap types may be more suited to WNV surveillance. To test the validity of these assertions, we conducted a series of trapping trials and WNV surveillance over 3 yr to compare the efficacy of multiple trap types. First, we compared the CDC Gravid trap, CO2-baited New Standard Miniature Blacklight traps, and CO2-baited CDC light traps with either …

Elevated Incidences Of Antimicrobial Resistance And Multidrug Resistance In The Maumee River (Ohio, Usa), A Major Tributary Of Lake Erie, Maitreyee Mukherjee, Leah Marie, Cheyenne Liles, Nadia Mustafa, George Bullerjahn, Terry J. Gentry, John P. Brooks

Faculty Publications

Maumee River, the major tributary in the western basin of Lake Erie, serves as one of major sources of freshwater in the area, supplying potable, recreational, and industrial water. In this study we collected water samples from four sites in the Maumee River Bay between 2016–2017 and E. coli was isolated, enumerated, and analyzed for antimicrobial resistance (AMR) and multidrug resistance (MDR). Strikingly, 95% of the total isolates were found to be resistant to at least one antibiotic. A very high resistance to the drugs cephalothin (95.3%), ampicillin (38.3%), tetracycline (8.8%), gentamicin (8.2%), ciprofloxacin (4.2%), cefoperazone (4%), and sulfamethoxazole (1.5%) …

Heavy Metal-Resistant Filamentous Fungi As Potential Mercury Bioremediators, Cristina L. Văcar, Eniko Covaci, Somsubhra Chakraborty, Bin Li, David Weindorf, Tiberiu Frentiu, Marcel Pârvu, Dorina Podar

Faculty Publications

No abstract provided.

Conceptus Metabolomic Profiling Reveals Stage-Specific Phenotypes Leading Up To Pregnancy Recognition In Cattle†, Constantine A. Simintiras, José M. Sánchez, Michael Mcdonald, Elena O'Callaghan, Ahmed A. Aburima, Patrick Lonergan

Faculty Publications

Reproductive efficiency in livestock is a major driver of sustainable food production. The poorly understood process of ruminant conceptus elongation (a) prerequisites maternal pregnancy recognition, (b) is essential to successful pregnancy establishment, and (c) coincides with a period of significant conceptus mortality. Conceptuses at five key developmental stages between Days 8-16 were recovered and cultured in vitro for 6 h prior to conditioned media analysis by untargeted ultrahigh-performance liquid chromatography tandem mass spectroscopy. This global temporal biochemical interrogation of the ex situ bovine conceptus unearths two antithetical stage-specific metabolic phenotypes during tubular (metabolically retentive) vs. filamentous (secretory) development. Moreover, the …

Polycyclic Aromatic Hydrocarbon-Dna Adducts In Gulf Of Mexico Sperm Whale Skin Biopsies Collected In 2012, Miriam C. Poirier, Letizia Marsili, Maria Cristina Fossi, Céline A.J. Godard-Codding, Elena E. Hernandez-Ramon, Nancy Si, Kathyayini V. Divi, Rao L. Divi, Iain Kerr, John Pierce Wise, John Pierce Wise, Catherine F. Wise, Sandra S. Wise, Abou El Makarim Aboueissa, James T.F. Wise

Faculty Publications

The northern Gulf of Mexico has a long history of polycyclic aromatic hydrocarbon (PAH) contamination from anthropogenic activities, natural oil seepages, and the 2010 Deepwater Horizon explosion and oil spill. The continental shelf of the same area is a known breeding ground for sperm whales (Physeter macrocephalus). To evaluate PAH-DNA damage, a biomarker for potential cancer risk, we compared skin biopsies collected from Gulf of Mexico sperm whales in 2012 with skin biopsies collected from sperm whales in areas of the Pacific Ocean in 1999-2001. All samples were obtained by crossbow and comprised both epidermis and subcutaneous blubber. To evaluate …

Circadian Rhythms In Legumes: What Do We Know And What Else Should We Explore?, Hazel Marie Kugan, Nur Ardiyana Rejab, Nurul Amylia Sahruzaini, Jennifer Ann Harikrishna, Niranjan Baisakh, Acga Cheng

Faculty Publications

The natural timing devices of organisms, commonly known as biological clocks, are composed of specific complex folding molecules that interact to regulate the circadian rhythms. Circadian rhythms, the changes or processes that follow a 24‐h light–dark cycle, while endogenously programmed, are also influenced by environmental factors, especially in sessile organisms such as plants, which can impact ecosystems and crop productivity. Current knowledge of plant clocks emanates primarily from research on Arabidopsis, which identified the main components of the circadian gene regulation network. Nonetheless, there remain critical knowledge gaps related to the molecular components of circadian rhythms in important crop groups, …

Insecticidal Rna Interference, Thinking Beyond Long Dsrna, Alex S. Flynt

Faculty Publications

Over 20 years ago double-stranded RNA (dsRNA) was described as the trigger of RNAi interference (RNAi)-based gene silencing. This paradigm has held since, especially for insect biopesticide technologies where dsRNAs, similar to those described in 1998, are used to inhibit gene expression. In the intervening years, investigation of RNAi pathways has revealed the small RNA effectors of RNAi are diverse and rapidly evolving. The rich biology of insect small RNAs suggests potential to use multiple RNAi modes for manipulating gene expression. By exploiting different RNAi pathways, the menu of options for pest control can be expanded and could lead to …

Teaching Leadership In American Law Schools: Why The Pushback?, Martin H. Brinkley

Faculty Publications

In September 2020, I participated in a panel discussion with several other deans at Baylor Law School’s 2020: Vision for Leadership Conference. The subject was “Leadership Programming in Law Schools.”

My assignment was to account for why teaching leadership might meet with resistance from inside law schools, despite widespread agreement that lawyer-leaders have always been and are always likely be critical to the survival of American democracy, as well as our fellow citizens’ hopes of living meaningful, satisfying lives.

This essay endeavors to memorialize and expand on the views I expressed on the panel.

Building Resilience In Children And Youth, Alina M. Baltazar, Gary L. Hopkins

Faculty Publications

No one is immune to life’s challenges. The COVID-19 pandemic has made that clear to any doubters and raised the issue of “resilience” into the top tiers of popular news topics. Resilience is the capacity to maintain competent functioning in the face of major life stressors. Since social problems are not going away, how do we create a culture in which children can do well in spite of adverse life experiences? Resilience is not a personality trait that someone is born with, but rather a capacity that develops over time. Think of resilience as a balance with negative life experiences …

Recent Advances In Understanding Tick And Rickettsiae Interactions, Shahid Karim, Deepak Kumar, Khemraj Budachetri

Faculty Publications

Ticks are haematophagous arthropods with unique molecular mechanisms for digesting host blood meal while acting as vectors for various pathogens of public health significance. The tick's pharmacologically active saliva plays a fundamental role in modulating the host's immune system for several days to weeks, depending on the tick species. The vector tick has also developed sophisticated molecular mechanisms to serve as a competent vector for pathogens, including the spotted fever group (SFG) rickettsiae. Evidence is still inadequate concerning tick–rickettsiae–host interactions and saliva-assisted transmission of the pathogen to the mammalian host. Rickettsia parkeri, of the SFG rickettsia, can cause a …

Characterization Of The Differential Expressed Genes And Transcriptomic Pathway Analysis In The Liver Of Sub-Adult Red Drum (Sciaenops Ocellatus) Exposed To Deepwater Horizon Chemically Dispersed Oil, Tracy A. Sherwood, Maria L. Rodgers, Andrea M. Tarnecki, Dana L. Wetzel

Faculty Publications

The Deepwater Horizon blowout resulted in the second-largest quantity of chemical dispersants used as a countermeasure for an open water oil spill in the Gulf of Mexico. Of which, the efficacy of dispersant as a mitigation strategy and its toxic effects on aquatic fauna remains controversial. To enhance our understanding of potential sub-lethal effects of exposure to chemically dispersed-oil, sub-adult red drum (Sciaenops ocellatus) were continuously exposed to a Corexit 9500: DWH crude oil chemically enhanced water accommodated fraction (CEWAF) for 3-days and transcriptomic responses were assessed in the liver. Differential expressed gene (DEG) analysis demonstrated that 63 …

Mobile App Privacy In Software Engineering Research: A Systematic Mapping Study, Fahimeh Ebrahimi, Miroslav Tushev, Anas Mahmoud

Faculty Publications

Context: Mobile applications (apps) have become deeply personal, constantly demanding access to privacy-sensitive information in exchange for more personalized user experiences. Such privacy-invading practices have generated major multidimensional privacy concerns among app users. Objective: The research on mobile app privacy has experienced rapid growth over the past decade. This line of research is aimed at systematically exposing the privacy practices of apps and proposing solutions to protect the privacy of mobile app users. In this paper, we conduct a systematic mapping study of this body of research. Our objectives are to a) explore trends in SE app privacy research, b) …

Real-Time Motion Tracking Of Cognitive Baxter Robot Based On Differential Inverse Kinematics, Shaobo Li, Xingxing Zhang, Jing Yang, Qiang Bai, Jianjun Hu, Qisong Song, Zhiang Li

Faculty Publications

The tracking motion of the robot is realized based on a specific robot or relying on an expensive movement acquisition system. It has the problems of complex control procedures, lack of real-time performance, and difficulty in achieving secondary development. We propose a robot real-time tracking control method based on the control principle of differential inverse kinematics, which fuses the position and joint angle information of the robot’s actuators to realize the real-time estimation of the user’s movement during the tracking process. The motion coordinates of each joint of the robot are calculated and the coordinate conversion between man and machine …

Speech Sound Disorders Syllabus And Unit Plan: Mini-Unit, Basic Ssd Assessment., Jenica Joseph

Faculty Publications

No abstract provided.

Association Between Dietary Inflammatory Index, Dietary Patterns, Plant-Based Dietary Index And The Risk Of Obesity, Yoko B. Wang, Nitin Shivappa, James R. Hébert Scd, Amanda J. Page, Yohannes Adama Melaku

Faculty Publications

Evidence on the association between various dietary constructs and obesity risk is limited. This study aims to investigate the longitudinal relationship between different diet indices and dietary patterns with the risk of obesity. Non-obese participants (n = 787) in the North West Adelaide Health Study were followed from 2010 to 2015. The dietary inflammatory index (DII®), plant-based dietary index (PDI) and factor-derived dietary pattern scores were computed based on food frequency questionnaire data. We found the incidence of obesity was 7.62% at the 5-year follow up. In the adjusted model, results from multivariable log-binomial logistic regression showed that a prudent …

Diet Quality And Risk Of Lung Cancer In The Multiethnic Cohort Study, Song-Yi Park, Carol J. Boushey, Yurii B. Shvetsov, Michael David Wirth Msph,Ph.D., Nitin Shivappa Ph.D., James R. Hébert Sc.D., Christopher A. Haiman, Lynee R. Wilkens, Loic Le Marchand

Faculty Publications

Diet quality, assessed by the Healthy Eating Index-2015 (HEI-2015), the Alternative Healthy Eating Index-2010 (AHEI-2010), the alternate Mediterranean Diet (aMED) score, the Dietary Approaches to Stop Hypertension (DASH) score, and the Dietary Inflammatory Index (DII®), was examined in relation to risk of lung cancer in the Multiethnic Cohort Study. The analysis included 179,318 African Americans, Native Hawaiians, Japanese Americans, Latinos, and Whites aged 45–75 years, with 5350 incident lung cancer cases during an average follow-up of 17.5 ± 5.4 years. In multivariable Cox models comprehensively adjusted for cigarette smoking, the hazard ratios (95% confidence intervals) for the highest vs. lowest …

Association Between Appendicular Skeletal Muscle Index And Leukocyte Telomere Length In Adults: A Study From National Health And Nutrition Examination Survey (Nhanes) 1999-2002, Lingzhi Chen, Nitin Shivappa Mbbs, Mph, Ph.D., Xiuxun Dong, Jinjing Ming

Faculty Publications

Background

A higher body mass index (BMI) is associated with shorter telomeres. The loss of muscle mass with aging is associated with adverse outcomes. The appendicular skeletal muscle index (ASMI) is currently used to quantify muscle mass.

Objective

We investigated the association of the ASMI with leukocyte telomere length in adult Americans.

Methods

This cross-sectional study used the National Health and Nutrition Examination Survey (NHANES) 1999–2002 dataset. Body composition was measured by dual-energy X-ray absorptiometry. Low muscle mass was defined using sex-specific thresholds of the appendicular skeletal muscle mass index (ASMI). The telomere-to-single-copy gene ratio (T/S ratio) was converted to …

Relationship Among Combat Experience, Veteran Pathology, And Pathology Of Veterans’ Intimate Partners: Factors Predicting The Pathology Of Veterans And Their Intimate Partners, Edwin A. Brennan, Nancy Carbonell, Jimmy Kijai, Dennis Waite

Faculty Publications

Introduction: Military members and their families have been part of the Global War on Terrorism since the September 11, 2001, terrorist attacks on the United States. As a result, higher levels of pathology — such as posttraumatic stress disorder, generalized anxiety disorder, and depression — are being seen. No known studies have addressed the concept of resonating pathology between combat Veterans and their intimate partners. Resonating pathology, for the purpose of this study, is when the combat Veteran and their intimate partner demonstrate the same pathology at similar levels. Methods: Veterans and their intimate partners from across the United States …

A Scapegoat Theory Of Bivens, Katherine Mims Crocker

Faculty Publications

Some scapegoats are innocent. Some warrant blame, but not the amount they are made to bear. Either way, scapegoating can allow in-groups to sidestep social problems by casting blame onto out-groups instead of confronting such problems--and the in-groups' complicity in perpetuating them--directly.

This Essay suggests that it may be productive to view the Bivens regime's rise as countering various exercises in scapegoating and its retrenchment as constituting an exercise in scapegoating. The earlier cases can be seen as responding to social structures that have scapegoated racial, economic, and other groups through overaggressive policing, mass incarceration, and inequitable government conduct more …

Managing Family Stress: Coping, Adapting And Becoming Resilient, Jasmine Fraser

Faculty Publications

No abstract provided.

Roboethics In Covid-19: A Case Study In Dentistry, Wendy C. Birmingham, Yaser Maddahi, Maryam Kalvandi, Sofya Langman, Nicole Capicotto, Kourosh Zareinia

Faculty Publications

The COVID-19 pandemic has caused dramatic effects on the healthcare system, businesses, and education. In many countries, businesses were shut down, universities and schools had to cancel in-person classes, and many workers had to work remotely and socially distance in order to prevent the spread of the virus. These measures opened the door for technologies such as robotics and artificial intelligence to play an important role in minimizing the negative effects of such closures. There have been many efforts in the design and development of robotic systems for applications such as disinfection and eldercare. Healthcare education has seen a lot …

Where To Draw The Line: The Endless Search For A Legal Competitive Edge, Andrew Brandt

Faculty Publications

No abstract provided.

Implementation Of The Cognitive Apprenticeship Model For Enhancement Of Advanced Searching Skills In A Pharmacy Academia Rotation: Appendices 1-4, Hilary Jasmin Msis, Kenneth Hohmeier Pharmd, Christina Spivey Pharmd, Phd

Faculty Publications

No abstract provided.

Healthy Eating In Low-Income Rural Louisiana Parishes: Formative Research For Future Social Marketing Campaigns, Linda Fergus, Richie Roberts, Denise Holston

Faculty Publications

No abstract provided.