Digital Commons Network^™

Suas For 3d Tree Surveying: Comparative Experiments On A Closed-Canopy Earthen Dam, Cuizhen Wang, Grayson R. Morgan, Michael E. Hodgson

Faculty Publications

Defined as “personal remote sensing”, small unmanned aircraft systems (sUAS) have been increasingly utilized for landscape mapping. This study tests a sUAS procedure of 3D tree surveying of a closed-canopy woodland on an earthen dam. Three DJI drones—Mavic Pro, Phantom 4 Pro, and M100/RedEdge-M assembly—were used to collect imagery in six missions in 2019–2020. A canopy height model was built from the sUAS-extracted point cloud and LiDAR bare earth surface. Treetops were delineated in a variable-sized local maxima filter, and tree crowns were outlined via inverted watershed segmentation. The outputs include a tree inventory that contains 238 to 284 trees …

Ecosytem Services: Delivering Decision-Making For Salt Marshes, Philine S. E. Zu Ermgassen, Ronald Baker, Michael W. Beck, Kate Dodds, Sophus O. S. E. Zu Ermgassen, Debbrota Mallick, Matthew D. Taylor, R. Eugene Turner

Faculty Publications

No abstract provided.

Repurposing Of Antibiotics For Clinical Management Of Covid-19: A Narrative Review, Abdourahamane Yacouba, Ahmed Olowo-Okere, Ismaeel Yunusa Ph.D.

Faculty Publications

Background: Drug repurposing otherwise known as drug repositioning or drug re-profling is a time-tested approach in drug discovery through which new medical uses are being established for already known drugs. Antibi‑ otics are among the pharmacological agents being investigated for potential anti-SARS-COV-2 activities. The antibiot‑ ics are used either to resolve bacterial infections co-existing with COVID-19 infections or exploitation of their potential antiviral activities. Herein, we aimed to review the various antibiotics that have been repositioned for the manage‑ ment of COVID-19.

Methods: This literature review was conducted from a methodical search on PubMed and Web of Science regarding antibiotics …

Australian Smokers' Sensory Experiences And Beliefs Associated With Menthol And Non-Menthol Cigarettes, Serafino Mancuso, Emily Brennan, Kimberley Dunstone, Amanda Vittiglia, Sarah Durkin, Jim F. Thrasher Ph.D., Ma, Ms, Janet Hoek, Melanie Wakefield

Faculty Publications

Many current smokers incorrectly believe that menthol cigarettes are less harmful, likely due to the biological and sensory effects of menthol, which can lead smokers to have favourable sensory experiences. In this study, we measured the extent to which Australian smokers associate certain sensory experiences with smoking menthol and non-menthol cigarettes, and their beliefs about how damaging and enjoyable they find cigarettes with each of these sensory experiences. A sample of 999 Australian 18–69-year-old weekly smokers was recruited from a non-probability online panel; this study focuses on the 245 respondents who currently smoked menthol cigarettes at least once per week. …

Examination Of Weight-Loss Motivators And Family Factors In Relation To Weight Management Strategies And Dietary Behaviors Among Adolescents With Obesity, Bridget K. Biggs, Dawn K. Wilson, Mary Quattlebaum, Seema Kumar, Alicia Meek, Teresa B. Jensen

Faculty Publications

The study aim was to test hypotheses informed by self-determination theory (SDT) regarding associations of adolescent motivators for weight loss and family feeding practices on understanding adolescent weight management and dietary behaviors. Adolescents (n = 71) with obesity were recruited from a large medical center in the Midwest USA and completed questionnaire assessments via an online survey. Results supported hypotheses that endorsement of health motivators for weight loss, conceptualized as autonomous (intrinsic) motivation, and positive family support would be associated with healthier weight management practices and dietary behaviors. Nuanced findings related to social- and self-esteem-related motivators for weight loss indicated …

The Importance Of Size Ranges In Aerosol Instrument Intercomparisons: A Case Study For The Atmospheric Tomography Mission, Hongyu Guo, Pedro Campuzano-Jost, Benjamin A. Nault, Douglas A. Day, Jason C. Schroder, Dongwook Kim, Jack E. Dibb, Maximilian Dollner, Bernadett Weinzierl, Jose L. Jimenez

Faculty Publications

Aerosol intercomparisons are inherently complex as they convolve instrument-dependent detection efficiencies vs. size (which often change with pressure, temperature, or humidity) and variations in the sampled aerosol population, in addition to differences in chemical detection principles (e.g., inorganic-only nitrate vs. inorganic plus organic nitrate for two instruments). The NASA Atmospheric Tomography Mission (ATom) spanned four separate aircraft deployments which sampled the remote marine troposphere from 86∘ S to 82∘ N over different seasons with a wide range of aerosol concentrations and compositions. Aerosols were quantified with a set of carefully characterized and calibrated instruments, some based on particle sizing and …

Spatiotemporal Patterns Of Human Mobility And Its Association With Land Use Types During Covid-19 In New York City, Yuqin Jiang, Xiao Huang, Zhenlong Li

Faculty Publications

The novel coronavirus disease (COVID-19) pandemic has impacted every facet of society. One of the non-pharmacological measures to contain the COVID-19 infection is social distancing. Federal, state, and local governments have placed multiple executive orders for human mobility reduction to slow down the spread of COVID-19. This paper uses geotagged tweets data to reveal the spatiotemporal human mobility patterns during this COVID-19 pandemic in New York City. With New York City open data, human mobility pattern changes were detected by different categories of land use, including residential, parks, transportation facilities, and workplaces. This study further compares human mobility patterns by …

Effects Of Psychosocial Support Interventions On Survival In Inpatient And Outpatient Healthcare Settings: A Meta-Analysis Of 106 Randomized Controlled Trials, Connor Workman, Caleb Andrews, Bonnie Barton, Matthew Cook, Ryan Layton, Alexandra Morrey, Devin Petersen, Julianne Holt-Lunstad

Faculty Publications

Background

Hospitals, clinics, and health organizations have provided psychosocial support interventions for medical patients to supplement curative care. Prior reviews of interventions augmenting psychosocial support in medical settings have reported mixed outcomes. This meta-analysis addresses the questions of how effective are psychosocial support interventions in improving patient survival and which potential moderating features are associated with greater effectiveness.

Methods and findings

We evaluated randomized controlled trials (RCTs) of psychosocial support interventions in inpatient and outpatient healthcare settings reporting survival data, including studies reporting disease-related or all-cause mortality. Literature searches included studies reported January 1980 through October 2020 accessed from Embase, …

Effects Of Psychosocial Support Interventions On Survival In Inpatient And Outpatient Healthcare Settings: A Meta-Analysis Of 106 Randomized Controlled Trials, Timothy B. Smith, Julianne Holt-Lunstad

Faculty Publications

We evaluated randomized controlled trials (RCTs) of psychosocial support interventions in inpatient and outpatient healthcare settings reporting survival data, including studies reporting disease-related or all-cause mortality. LOdds ratio (OR) and hazard ratio (HR) data were analyzed separately using random effects weighted models. Of 42,054 studies searched, 106 RCTs including 40,280 patients met inclusion criteria. Across 87 RCTs reporting data for discrete time periods, the average was OR = 1.20 (95% CI = 1.09 to 1.31, p < 0.001), indicating a 20% increased likelihood of survival among patients receiving psychosocial support compared to control groups receiving standard medical care. Among those studies, psychosocial interventions explicitly promoting health behaviors yielded improved likelihood of survival, whereas interventions without that primary focus did not. Across 22 RCTs reporting survival time, the average was HR = 1.29 (95% CI = 1.12 to 1.49, p < 0.001), indicating a 29% increased probability of survival over time among intervention recipients compared to controls. Among those studies, meta-regressions identified 3 moderating variables: control group type, patient disease severity, and risk of research bias. Studies with patients having relatively greater disease severity tended to yield smaller gains in survival time relative to control groups. In this meta-analysis, OR data indicated that psychosocial behavioral support interventions promoting patient motivation/coping to engage in health behaviors improved patient survival, but interventions focusing primarily on patients’ social or emotional outcomes did not prolong life. HR data indicated that psychosocial interventions, predominantly focused on social or emotional outcomes, improved survival but yielded similar effects to health information/classes and were less effective among patients with apparently greater disease severity.

Development And Assessment Of Feasibility Of A Community-Based Peer Support Intervention To Mitigate Social Isolation And Stigma Of Adolescent Motherhood In Harare, Zimbabwe, Chiwoneso B. Tinago, Edward A. Frongillo Jr. Ph.D., Andrea M. Warren, Vivian Chitiyo, Ashley K. Cifarelli, Shannon Fyalkowski, Victoria Pauline

Faculty Publications

Background: Adolescent mothers in Zimbabwe often experience stigma, isolation, and lack coping skills and resources to successfully navigate motherhood. Social isolation and stigma are linked to poor mental health outcomes. No interventions currently address mental health of adolescent mothers in Zimbabwe. Peer support groups in other contexts have been effective at increasing social connectedness, self-esteem, and self-efficacy, providing coping mechanisms to manage stigma experiences, in addition to empowering and improving mental health of adolescents and adolescent mothers. To develop a community-based peer support intervention, we aimed to understand the unique needs of adolescent mothers, how peer support groups could …

Brief Overview Of Approaches And Challenges In New Antibiotic Development: A Focus On Drug Repurposing, Natalie K. Boyd, Chengwen Teng Pharm.D., Ph.D., Christopher R. Frei

Faculty Publications

Drug repurposing, or identifying new uses for existing drugs, has emerged as an alternative to traditional drug discovery processes involving de novo synthesis. Drugs that are currently approved or under development for non-antibiotic indications may possess antibiotic properties, and therefore may have repurposing potential, either alone or in combination with an antibiotic. They might also serve as “antibiotic adjuvants” to enhance the activity of certain antibiotics.

Community Support Model On Breastfeeding And Complementary Feeding Practices In Remote Areas In Vietnam: Implementation, Cost, And Effectiveness, Tuan T. Nguyen, Nemat Hajeebhoy, Jia Li, Chung T. Do, Roger Mathisen, Edward A. Frongillo Jr.

Faculty Publications

Background

Poor access to healthcare facilities and consequently nutrition counseling services hinders the uptake of recommended infant and young child feeding (IYCF) practices. To address these barriers and improve IYCF practices, Alive & Thrive (A&T) initiated community support groups in remote villages across nine provinces in Vietnam.

Objective

This study examines the effectiveness of the support group model and related project costs for reaching underserved areas to improve IYCF practices.

Methods

To evaluate the model’s implementation and project costs, we reviewed implementation guidelines, expenditure and coverage reports, monitoring data, and budgets for the nine provinces. To evaluate the model’s effectiveness, …

Differences In ​The Proportion Of Children Meeting Behavior Guidelines ​Between Summer ​And School By Socioeconomic Status And Race, Ethan T. Hunt, Lauren Von Klinggraeff, Alexis Jones, Sarah Burkart, Roddrick Dugger, Bridget Armstrong Ph.D., Michael Beets Ph.D., Gabrielle Turner-Mcgrievy Ph.D., Rd, Marco Geraci, Robert Glenn Weaver Med, Phd

Faculty Publications

Objective

Children who fail to meet activity, sleep, and screen-time guidelines are at increased risk for obesity. Further, children who are Black are more likely to have obesity when compared to children who are White, and children from low-income households are at increased risk for obesity when compared to children from higher-income households. The objective of this study was to evaluate the proportion of days meeting obesogenic behavior guidelines during the school year compared to summer vacation by race and free/reduced priced lunch (FRPL) eligibility.

Methods

Mixed-effects linear and logistic regressions estimated the proportion of days participants met activity, sleep, …

Cognitive Empathy And Longitudinal Changes In Temporo-Parietal Junction Thickness In Schizophrenia, Derin J. Cobia, Tatiana Karpouzian-Rogers, Julie Petersen, Lei Wang, Vijay A. Mittal, John G. Csernansky, Matthew J. Smith

Faculty Publications

Objective: Deficits in cognitive empathy are well-documented in individuals with schizophrenia and are related to reduced community functioning. The temporoparietal junction (TPJ) is closely linked to cognitive empathy. We compared the relationship between baseline cognitive empathy and changes in TPJ thickness over 24 months between individuals with schizophrenia and healthy controls. Methods: Individuals with schizophrenia (n = 29) and healthy controls (n = 26) completed a cognitive empathy task and underwent structural neuroimaging at baseline and approximately 24 months later. Symmetrized percent change scores were calculated for right and left TPJ, as well as whole-brain volume, and compared between groups. …

Prion-Like C-Terminal Domain Of Tdp-43 And Α-Synuclein Interact Synergistically To Generate Neurotoxic Hybrid Fibrils, Shailendra Dhakal, Courtney E. Wyant, Hannah E. George, Sarah E. Morgan, Vijayaraghavan Rangachari

Faculty Publications

Aberrant aggregation and amyloid formation of tar DNA binding protein (TDP-43) and α-synuclein (αS) underlie frontotemporal dementia (FTD) and Parkinson’s disease (PD), respectively. Amyloid inclusions of TDP-43 and αS are also commonly co-observed in amyotrophic lateral sclerosis (ALS), dementia with Lewy bodies (DLB) and Alzheimer disease (AD). Emerging evidence from cellular and animal models show colocalization of the TDP-43 and αS aggregates, raising the possibility of direct interactions and co-aggregation between the two proteins. In this report, we set out to answer this question by investigating the interactions between αS and prion-like pathogenic C-terminal domain of TDP-43 (TDP-43 PrLD). PrLD …

De Novo Transcriptome Assembly Of The Green Alga Ankistrodesmus Falcatus, Rachel A. Schomaker, Jeffry L. Dudycha

Faculty Publications

Ankistrodesmus falcatus is a globally distributed freshwater chlorophyte that is a candidate for biofuel production, is used to study the effects of toxins on aquatic communities, and is used as food in zooplankton research. Each of these research fields is transitioning to genomic tools. We created a reference transcriptome for of A. falcatus using NextGen sequencing and de novo assembly methods including Trinity, Velvet-Oases, and EvidentialGene. The assembled transcriptome has a total of 17,997 contigs, an N50 value of 2,462, and a GC content of 64.8%. BUSCO analysis recovered 83.3% of total chlorophyte BUSCOs and 82.5% of the eukaryotic …

Nanoantibiotics: Functions And Properties At The Nanoscale To Combat Antibiotic Resistance, M. Mustafa Mamun, Adeola Julian Sorinolu, Mariya Munir, Eric P. Vejerano

Faculty Publications

One primary mechanism for bacteria developing resistance is frequent exposure to antibiotics. Nanoantibiotics (nAbts) is one of the strategies being explored to counteract the surge of antibiotic resistant bacteria. nAbts are antibiotic molecules encapsulated with engineered nanoparticles (NPs) or artificially synthesized pure antibiotics with a size range of ≤100 nm in at least one dimension. NPs may restore drug efficacy because of their nanoscale functionalities. As carriers and delivery agents, nAbts can reach target sites inside a bacterium by crossing the cell membrane, interfering with cellular components, and damaging metabolic machinery. Nanoscale systems deliver antibiotics at enormous particle number concentrations. …

Environmentally Persistent Free Radicals As Sources Of Pops, Eric P. Vejerano, Jeonghyeon Ahn, Junaid Latif, Mustafa Mamun

Faculty Publications

Environmentally persistent free radicals (EPFRs) are a new class organic pollutant sharing some of the attributes of persistent organic pollutants (POPs). This opinion/short review aims to describe the properties of EPFRs that merit their recognition as an additional and potentially significant source of POPs. EPFRs are ubiquitous in diverse environments because of multiple factors: (1) organic precursors from anthropogenic, biogenic, and other natural emission sources are abundant; multiple mechanisms in PM and soils form (2) EPFRs; and (3) EPFRs are stable and persist for a long time, thereby, accumulate in the environment and potentially transported long range. The hazards of …

Modeled Changes In Source Contributions Of Particulate Matter During The Covid-19 Pandemic In The Yangtze River Delta, China, Jinlong Ma, Juanyong Shen, Peng Wang, Shengqiang Zhu, Yu Wang, Pengfei Wang, Gehui Wang, Jianmin Chen, Hongliang Zhang

Faculty Publications

Within a short time after the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, Hubei, the Chinese government introduced a nationwide lockdown to prevent the spread of the pandemic. The quarantine measures have significantly decreased the anthropogenic activities, thus improving air quality. To study the impacts caused by the lockdown on specific source sectors and regions in the Yangtze River Delta (YRD), the Community Multiscale Air Quality (CMAQ) model was used to investigate the changes in source contributions to fine particulate matter (PM2.5) from 23 January to 28 February 2020, based on different emission control cases. Compared to case 1 …

Cycling Phosphorus And Nitrogen Through Cropping Systems In An Intensive Dairy Production Region, April B. Leytem, Paula Williams, Shan Zuidema, Audrey Martinez, Yen Leng Chong, Alyssa Vincent, Aaron Vincent, Daniel Cronan, Andrew Kliskey, J. D. Wulfhorst, Lilian Alessa, David Bjorneberg

Faculty Publications

As pressure on the dairy industry to reduce its environmental impact increases, efficient recycling of manure nutrients through local cropping systems becomes crucial. The aim of this study was to calculate annual nitrogen (N) and phosphorus (P) budgets in six counties located in the Magic Valley, Idaho and estimate what distance manure would need to be transported to be in balance with crop nutrient demand given current dairy cattle populations and cropping systems. Our analysis suggests that crop N needs will not be met solely by manure, and synthetic fertilizer will need to be applied. However, to balance P with …

The Korea–United States Air Quality (Korus-Aq) Field Study, James H. Crawford, Joon-Youg Ahn, Jassim Al-Saadi, Limseok Chang, Louisa K. Emmons, Jhoon Kim, Gangwoong Lee, Jeong-Hoo Park, Rokjin J. Park, Jung Hun Woo, Chang-Keun Song, Ji-Hyung Hong, You-Deog Hong, Barry L. Lefer, Meehye Lee, Taehyoung Lee, Saewung Kim, Kyung-Eun Min, Seong Soo Yum, Hye Jung Shin, Young-Woo Kim, Jin-Soo Choi, Jin-Soo Park, James J. Szykman, Russell W. Long, Carolyn E. Jordan, Isobel J. Simpson, Alan Fried, Jack E. Dibb, Seogyeon Cho, Yong Pyo Kim

Faculty Publications

The Korea–United States Air Quality (KORUS-AQ) field study was conducted during May–June 2016. The effort was jointly sponsored by the National Institute of Environmental Research of South Korea and the National Aeronautics and Space Administration of the United States. KORUS-AQ offered an unprecedented, multi-perspective view of air quality conditions in South Korea by employing observations from three aircraft, an extensive ground-based network, and three ships along with an array of air quality forecast models. Information gathered during the study is contributing to an improved understanding of the factors controlling air quality in South Korea. The study also provided a valuable …

Covid-19: A Syndemic Requiring An Integrated Approach For Marginalized Populations, Rosemary M. Caron, Amanda Rodrigues Amorim Adegboye

Faculty Publications

The novel coronavirus, SARS-CoV-2, responsible for the COVID-19 pandemic, has challenged healthcare systems globally. The health inequities experienced by immigrants, refugees, and racial/ethnic minorities have been aggravated during the COVID-19 pandemic. The socioeconomic, political, and demographic profile of these vulnerable populations places them at increased risk of contracting COVID-19 and experiencing significant morbidity and mortality. Thus, the burden of the COVID-19 pandemic is disproportionally higher among these at-risk groups. The purpose of this perspective is to: (1) highlight the interactions among the social determinants of health (SDoH) and their bi-directional relationship with the COVID-19 pandemic which results in the current …

Fungal Community Response To Long-Term Soil Warming With Potential Implications For Soil Carbon Dynamics, Gregory J. Pec, Linda T. A. Van Diepen, Melissa A. Knorr, A. Stuart Grandy, Jerry M. Melillo, Kristen M. Deangelis, Jeffrey L. Blanchard, Serita D. Frey

Faculty Publications

The direction and magnitude of climate warming effects on ecosystem processes such as carbon cycling remain uncertain. Soil fungi are central to these processes due to their roles as decomposers of soil organic matter, as mycorrhizal symbionts, and as determinants of plant diversity. Yet despite their importance to ecosystem functioning, we lack a clear understanding of the long-term response of soil fungal communities to warming. Toward this goal, we characterized soil fungal communities in two replicated soil warming experiments at the Harvard Forest (Petersham, Massachusetts, USA) which had experienced 5°C above ambient soil temperatures for 5 and 20 yr at …

Differences In Effectiveness And Use Of Laparoscopic Surgery In Locally Advanced Colon Cancer Patients, M. Schootman, Matthew Mutch, T. Loux, Jan M. Eberth Ph.D., N. O. Davidson

Faculty Publications

Patients with locally advanced colon cancer have worse outcomes. Guidelines of various organizations are conflicting about the use of laparoscopic colectomy (LC) in locally advanced colon cancer. We determined whether patient outcomes of LC and open colectomy (OC) for locally advanced (T4) colon cancer are comparable in all colon cancer patients, T4a versus T4b patients, obese versus non-obese patients, and tumors located in the ascending, descending, and transverse colon. We used data from the 2013–2015 American College of Surgeons’ National Surgical Quality Improvement Program. Patients were diagnosed with nonmetastatic pT4 colon cancer, with or without obstruction, and underwent LC (n …

Management Intensive Grazing On New England Dairy Farms Enhances Soil Nitrogen Stocks And Elevates Soil Nitrous Oxide Emissions Without Increasing Soil Carbon, Alexandra R. Contosta, Kyle A. Arndt, Eleanor E. Campbell, A. Stuart Grandy, Apryl L. Perry, Ruth K. Varner

Faculty Publications

Management intensive grazing (MIG), also known as rotational grazing or multi-paddock grazing, is purported to sequester carbon (C) in soils compared to other agricultural management systems. Prior research examining the potential for MIG to enhance soil C has been inconclusive, and past investigations have not addressed whether higher nitrous oxide (N2O) emissions may accompany increases in soil C stocks. Here we examined linkages among MIG, soil C accumulation, and N2O emissions in cool-season, organic pastures of the northeastern United States. We found that pastures under MIG increased soil C concentrations by 11% from 0–15 cm depth but that soil C …

A Vision For Buchanan, Andrew C. Von Maur

Faculty Publications

No abstract provided.

Cardiovascular, Cellular, And Neural Adaptations To Hot Yoga Versus Normal-Temperature Yoga, Kelsey C. Bourbeau, Terence A. Moriarty, Bryanne N. Bellovary, Gabriella F. Bellissimo, Jeremy B. Ducharme, Truman J. Haeny, Micah N. Zuhl

Faculty Publications

Context:

Chronic heat exposure promotes cardiovascular and cellular adaptations, improving an organism's ability to tolerate subsequent stressors. Heat exposure may also promote neural adaptations and alter the neural–hormonal stress response. Hot-temperature yoga (HY) combines mind–body exercise with heat exposure. The added heat component in HY may induce cardiovascular and cellular changes, along with neural benefits and modulation of stress hormones.

Aims:

The purpose of the present study is to compare the cardiovascular, cellular heat shock protein 70 (HSP70), neural, and hormonal adaptations of HY versus normal-temperature yoga (NY).

Settings and Design:

Twenty-two subjects (males = 11 and females = 11, …

Walk Through The Famine And Distraught Of Life, Grace C. Chi, Jerry L. Chi

Faculty Publications

No abstract provided.

The Effect Of Phragmites Australis Dieback On Channel Sedimentation In The Mississippi River Delta: A Conceptual Modeling Study, Kelin Hu, Ehab Meselhe, J. Andrew Nyman

Faculty Publications

Phragmites australis is a globally distributed wetland plant. At the mouth of the Mississippi River, P. australis on natural levees of the network of distributary channels appears to increase the flow in the deep draft navigation channel, which, in turn, may reduce the sedimentation and benefit the navigation dredging. For several years, P. australis has been dying in the Mississippi River’s Bird’s Foot Delta, which appears to be shortening the distributary channels and increasing the lateral flow from the remaining portions. A conceptual model based on D-FLOW FM was applied to calculate channel sedimentation in a series of idealized deltaic …

Cancer Disparities And Black American Representation In Clinical Trials Leading To The Approval Of Oral Chemotherapy Drugs In The United States Between 2009 And 2019, Veronica Ajewole, Oyinkansola Akindele, Uzoamaka Abajue, Okwuoma Ndulue, Jazzmin J. Marshall, Yhenew T. Mossi

Faculty Publications

PURPOSE Over the past 10 years, oral chemotherapy made up about half (45.6%) of all US Food and Drug Administration (FDA)-approved oncolytic and hematologic medications. Given the disparity in incidence and mortality rate because of certain cancers among Black Americans (BAs) in theUnited States, a review of BA's representation in the clinical trials that lead to the development and FDA approval of oral chemotherapy drugs becomes imperative. The objective of this study was to evaluate the reporting of race and inclusion of BA in clinical trials that led to the approval of oral chemotherapy medications by the FDA from 2009 …