Digital Commons Network^™

Analysis Of Body Condition Indices Reveals Different Ecotypes Of The Antillean Manatee, D. N. Castelblanco-Martínez, D. H. Slone, S. S. Landeo-Yauri, E. A. Ramos, A. Alvarez-Alemán, F. L. N. Attademo, C. A. Beck, R. K. Bonde, S. M. Butler, L. J. Cabrias-Contreras, D. Caicedo-Herrera, J. Galves, I. V. Gómez-Camelo, Daniel Gonzalez-Socoloske, J. Jiménez-Domínguez, F. O. Luna, Y. Mona-Sanabria, J. B. Morales-Vela, L. D. Olivera-Gómez, J. A. Padilla-Saldívar, J. Powell, J. P. Reid, G. Rieucau, A. A. Mignucci-Giannoni

Faculty Publications

Assessing the body condition of wild animals is necessary to monitor the health of the population and is critical to defining a framework for conservation actions. Body condition indices (BCIs) are a non-invasive and relatively simple means to assess the health of individual animals, useful for addressing a wide variety of ecological, behavioral, and management questions. The Antillean manatee (Trichechus manatus manatus) is an endangered subspecies of the West Indian manatee, facing a wide variety of threats from mostly human-related origins. Our objective was to define specific BCIs for the subspecies that, coupled with additional health, genetic and …

The Response Of Airborne Mycobiome To Dust Storms In The Eastern Mediterranean, Xuefeng Peng, Daniela Gat, Adina Paytan, Yinon Rudich

Faculty Publications

Airborne microbial communities directly impact the health of humans, animals, plants, and receiving ecosystems. While airborne bacterial and fungal communities have been studied by both cultivation-based methods and metabarcoding surveys targeting specific molecular markers, fewer studies have used shotgun metagenomics to study the airborne mycobiome. We analyzed the diversity and relative abundance of fungi in nine airborne metagenomes collected on clear days (“background”) and during dust storms in the Eastern Mediterranean. The negative correlation between the relative abundance of fungal reads and the concentrations of atmospheric particulate matter having an aerodynamic diameter smaller than 10 μm (PM10) indicate that dust …

Estimated Prevalence Of Smoking And Smoking-Attributable Mortality Associated With Graphic Health Warnings On Cigarette Packages In The Us From 2022 To 2100, Jamie Tam, Jihyoun Jeon, Jim Thrasher Ph.D., Ma, Ms, David Hammond, Theodore R. Holford, David T. Levy, Rafael Meza

Faculty Publications

Question What are the estimated population health outcomes associated with implementation of graphic health warnings on cigarette packages in 2022 and with delayed implementation of the warnings since 2012, as originally planned, in the US?

Findings In this decision analytical model using simulation modeling of smoking prevalence and smoking-attributable mortality in the US from 2012 to 2100, graphic health warnings, if implemented from 2022 to 2100, would be associated with 539 000 smoking-attributable deaths averted and 7.9 million life-years gained, and if implemented in 2012, with 718 000 deaths averted and 11.2 million life-years gained through 2100.

Meaning These findings …

Computationally Assisted Lead Optimization Of Novel Potent And Selective Mao-B Inhibitors, Vedanjali Goineni, Manal A. Neal, Narayan D. Chaurasiya, Khaled M. Elokely, Christopher R. Mccurdy, John M. Rimoldi, Stephen J. Cutler Ph.D., Babu L. Tekwani, Francisco León Ph.D.

Faculty Publications

A series of dietary flavonoid acacetin 7-O-methyl ether derivatives were computationally designed aiming to improve the selectivity and potency profiles against monoamine oxidase (MAO) B. The designed compounds were evaluated for their potential to inhibit human MAO-A and -B. Compounds 1c, 2c, 3c, and 4c were the most potent with a Ki of 37 to 68 nM against MAO-B. Compounds 1c–4c displayed more than a thousand-fold selectivity index towards MAO-B compared with MAO-A. Moreover, compounds 1c and 2c showed reversible inhibition of MAO-B. These results provide a basis for further studies on the potential application of these modified flavonoids for …

Men’S Comfort In Distributing Or Receiving Hiv Self-Test Kits From Close Male Social Network Members In Dar Es Salaam, Tanzania: Baseline Results From The Step Project, Joseph K.B. Matovu, Gaspar Mbita, Akeen Hamilton, Frank Mhando, Wynton M. Sims, Noah Thompson, Albert N. Komba, Jackson Lija, Jiajia Zhang Ph.D., Thomas Van Den Akker, Dustin T. Duncan, Augustine T. Choko, Donaldson F. Conserve

Faculty Publications

Background

A variety of strategies have been used to reach men with HIV self-testing services, including social network-based HIV self-test kits distribution. However, few studies have assessed men’s comfort to distribute to or receive HIV self-test kits from close male friends within the same social network. In this study, we assessed men’s comfort to distribute to and/or receive HIV self-test kits from close male friends and associated factors among men who socialize in networks locally referred to as “camps” in Tanzania.

Methods

Data are from the baseline survey of a cluster-randomized controlled trial conducted in June 2019 with 18 social …

Facial Expression Processing Of Children Orphaned By Parental Hiv/Aids: A Cross-Sectional Erp Study With Rapid Serial Visual Presentation, Qiong Zhao, Hui He, Huang Gu, Junfeng Zhao, Peilian Chi, Xiaoming Li Ph.D.

Faculty Publications

Existing behavioral studies have suggested that individuals with early life stress usually show abnormal emotional processing. However, limited event-related brain potentials (ERPs) evidence was available to explore the emotional processes in children orphaned by parental HIV/AIDS (“AIDS orphans”). The current study aims to investigate whether there are behavioral and neurological obstacles in the recognition of emotional faces in AIDS orphans and also to further explore the processing stage at which the difference in facial emotion recognition exists. A total of 81 AIDS orphans and 60 non-orphan children were recruited through the local communities and school systems in Henan, China. Participants …

The Assessment Of An Extended Set Of Socio-Economic Determinants To Explain Anxiety And Uncertainty, Insufficient Quality And Food Intake Of Afghan Refugees, Mohammad Reza Pakravan-Charvadeh, Hassan Vatanparast, Edward A. Frongillo Jr., Mahasti Khakpour, Cornelia Flora

Faculty Publications

OBJECTIVES:

In this study, socio-economic factors associated with Afghan refugee households' food insecurity, anxiety and uncertainty, insufficient quality and food intake were determined.

DESIGN:

Household Food Insecurity Assess Scale measurement was applied to assess food insecurity, anxiety and uncertainty, insufficient quality and insufficient food intake. Descriptive analysis and multivariable regression models were used to determine the associated factors.

SETTING:

The study was carried out in urban areas of Tehran province in Iran. PARTICIPANTS: To collect data, interviews were conducted among 317 Afghan households. The questionnaire was administered via face-to-face interviews to either the breadwinner of the selected households or a …

Recognition And Screening For Chagas Disease In The Usa, Rachel Marcus, Andres F. Henao-Martinez, Melissa Nolan Ph.D., Mph, Elizabeth Livingston, Stephen A. Klotz, Robert H. Gilman, Monica Miranda-Schaeubinger, Sheba Meymandi

Faculty Publications

Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a public health concern, mainly among countries in South and Central America. However, despite the large number of immigrants from endemic countries living in the USA, awareness of CD is poor in the medical community, and therefore it is significantly underdiagnosed. To avoid the catastrophic cardiac complications of CD and to prevent maternal–fetal transmission, widespread educational programs highlighting the need for diagnosis are urgently needed.

Towards Detection Of Sars-Cov-2 Rna In Human Saliva: A Paper-Based Cell-Free Toehold Switch Biosensor With A Visual Bioluminescent Output, J. Porter Hunt, Emily Long Zhao, Tyler J. Free, Mehran Soltani, Chandler A. Warr, Alex B. Benedict, Melissa K. Takahashi, Joel S. Griffitts, William G. Pitt, Bradley C. Bundy

Faculty Publications

The COVID-19 pandemic has illustrated the global demand for rapid, low-cost, widely distributable and point-of-care nucleic acid diagnostic technologies. Such technologies could help disrupt transmission, sustain economies and preserve health and lives during widespread infection. In contrast, conventional nucleic acid diagnostic procedures require trained personnel, complex laboratories, expensive equipment, and protracted processing times. In this work, lyophilized cell-free protein synthesis (CFPS) and toehold switch riboregulators are employed to develop a promising paper-based nucleic acid diagnostic platform activated simply by the addition of saliva. First, to facilitate distribution and deployment, an economical paper support matrix is identified and a mass-producible test …

Concussion History And Heart Rate Variability During Bouts Of Acute Stress, Adam Harrison, Abbi Lane-Cordova, Michael F. La Fountaine, Robert Davis Moore Ms, Ph.D.

Faculty Publications

Context

After a sport-related concussion, many athletes experience persisting neurophysiological alterations. These alterations may be absent at rest but emerge during moments of physiological stress. Unnoticed and untreated neurophysiological dysfunction may negatively affect long-term neurologic health in adolescent athletes, as they are at a critical point in development. Objective

To assess cardio-autonomic functioning in athletes with and those without a history of concussion by quantifying measures of heart rate variability (HRV) during times of physical and mental exertion. Design

Case-control study. Setting

Research laboratory. Patients or Other Participants

Thirty-four male Hockey Quebec Midget-AAA hockey players were separated into those with …

Advancing Use Of Nutrition Knowledge To Improve Practice By Policy And Program Communities In India During A Political Transition, Edward A. Frongillo Jr., Jessica L. Escobar-Alegria

Faculty Publications

Models are needed for how to advance use of knowledge by programs and policy officials to make evidence-based decisions about nutrition. How to advance use of nutrition knowledge in India from 2011 to 2015 during a political transition was investigated through studying a knowledge initiative led by the International Food Policy Research Institute. Semistructured interviews were conducted with 37 diverse participants, and 1091 news articles, 318 Twitter and 175 Facebook posts, 12 YouTube events, 65 knowledge products, and 130 engaging events were assessed. Open-axial coding, content and themes analysis, triangulation, and process tracing were used. The knowledge initiative analyzed the …

The Ghost Of Hosts Past: Impacts Of Host Extinction On Parasite Specificity, Maxwell J. Farrell, Andrew W. Park, Clayton E. Cressler, Tad Dallas, Shan Huang, Nicole Mideo, Ignacio Morales-Castilla, T. Jonathan Davies, Patrick Stephens

Faculty Publications

A growing body of research is focused on the extinction of parasite species in response to host endangerment and declines. Beyond the loss of parasite species richness, host extinction can impact apparent parasite host specificity, as measured by host richness or the phylogenetic distances among hosts. Such impacts on the distribution of parasites across the host phylogeny can have knock-on effects that may reshape the adaptation of both hosts and parasites, ultimately shifting the evolutionary landscape underlying the potential for emergence and the evolution of virulence across hosts. Here, we examine how the reshaping of host phylogenies through extinction may …

The Future Of Zoonotic Risk Prediction, Colin J. Carlson, Maxwell J. Farrell, Zoe Grange, Barbara A. Han, Nardus Mollentze, Alexandra L. Phelan, Angela L. Rasmussen, Gregory F. Albery, Bernard Bett, David M. Brett-Major, Lily E. Cohen, Tad Dallas, Evan A. Eskew, Anna C. Fagre, Kristian M. Forbes, Rory Gibb, Sam Halabi, Charlotte C. Hammer, Rebecca Katz, Jason Kindrachuk, Renata L. Muylaert, Felicia B. Nutter, Joseph Ogola, Kevin J. Olival, Michelle Rourke, Sadie J. Ryan, Noam Ross, Stephanie N. Seifert, Tarja Sironen, Claire J. Standley, Kishana Taylor, Marietjie Venter, Paul W. Webala

Faculty Publications

In the light of the urgency raised by the COVID-19 pandemic, global investment in wildlife virology is likely to increase, and new surveillance programmes will identify hundreds of novel viruses that might someday pose a threat to humans. To support the extensive task of laboratory characterization, scientists may increasingly rely on data-driven rubrics or machine learning models that learn from known zoonoses to identify which animal pathogens could someday pose a threat to global health. We synthesize the findings of an interdisciplinary workshop on zoonotic risk technologies to answer the following questions. What are the prerequisites, in terms of open …

Adolescent Victim Types Across The Popularity Status Hierarchy: Differences In Internalizing Symptoms, Sarah T. Malamut, Molly Dawes, Yvonne Van Den Berg, Tessa A.M. Lansu, David Schwartz, Antonius H.N. Cillessen

Faculty Publications

Previous studies have called attention to the fact that popular youth are not immune to peer victimization, suggesting there is heterogeneity in the popularity of victims. Yet, no study to date has determined whether victims with different levels of popularity status can be identified using person-oriented analysis. Such analysis is critically needed to confirm the existence of popular victims. Further, there remains a paucity of research on internalizing indices of such popular victims, especially compared to other victim and non-victim groups. To address this gap in the research literature, the current study used latent profile analysis to identify subgroups of …

A Structural Study Of The Cytoplasmic Chaperone Effect Of 14-3-3 Proteins On Ataxin-1, Seppe Leysen, Rebecca Jane Burnley, Elizabeth Rodriguez, Lech-Gustav Milroy, Lorenzo Soini, Carolyn J. Adamski, Larissa Nitschke, Rachel Davis, Tomas Obsil, Lucas Brunsveld, Tom Crabbe, Huda Yahya Zoghbi, Christian Ottmann, Jeremy Martin Davis

Faculty Publications

Expansion of the polyglutamine tract in the N terminus of Ataxin-1 is the main cause of the neurodegenerative disease, spinocerebellar ataxia type 1 (SCA1). However, the C-terminal part of the protein - including its AXH domain and a phosphorylation on residue serine 776 - also plays a crucial role in disease development. This phosphorylation event is known to be crucial for the interaction of Ataxin-1 with the 14-3-3 adaptor proteins and has been shown to indirectly contribute to Ataxin-1 stability. Here we show that 14-3-3 also has a direct anti-aggregation or "chaperone" effect on Ataxin-1. Furthermore, we provide structural and …

Identifying Effective Intervention Strategies To Reduce Children’S Screen Time: A Systematic Review And Meta-Analysis, Alexis Jones, Bridget Armstrong Ph.D., Robert Glenn Weaver M.Ed., Phd, Hannah Parker, Lauren Von Klinggraeff, Michael W. Beets Ph.D.

Faculty Publications

Background

Excessive screen time (≥ 2 h per day) is associated with childhood overweight and obesity, physical inactivity, increased sedentary time, unfavorable dietary behaviors, and disrupted sleep. Previous reviews suggest intervening on screen time is associated with reductions in screen time and improvements in other obesogenic behaviors. However, it is unclear what study characteristics and behavior change techniques are potential mechanisms underlying the effectiveness of behavioral interventions. The purpose of this meta-analysis was to identify the behavior change techniques and study characteristics associated with effectiveness in behavioral interventions to reduce children’s (0–18 years) screen time.

Methods

A literature search of …

Epidemiology Of Type 2 Diabetes In The Middle East And North Africa: Challenges And Call For Action, Imad El-Kebbi, Nayda Bidikian, Layal Hneiny, Mona Nasrallah

Faculty Publications

Type 2 diabetes continues to be a serious and highly prevalent public health problem worldwide. In 2019, the highest prevalence of diabetes in the world at 12.2%, with its associated morbidity and mortality, was found in the Middle East and North Africa region. In addition to a genetic predisposition in its population, evidence suggests that obesity, physical inactivity, urbanization, and poor nutritional habits have contributed to the high prevalence of diabetes and prediabetes in the region. These risk factors have also led to an earlier onset of type 2 diabetes among children and adolescents, negatively affecting the productive years of …

Pre-Exposure Prophylaxis (Prep) Uptake Among Black Men Who Have Sex With Men (Bmsm) In The Southern U.S, Oluwafemi Adeagbo, Sayward Elizabeth Harrison, Shan Qiao Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Black men who have sex with men (BMSM) living in the United States (U.S.) South are disproportionately affected by HIV and experience significant disparities in HIV incidence, access to HIV care, and prevention across ages and socio-economic statuses. The aim of this commentary is to critically review current literature on the state of PrEP use among BMSM in the U.S. South, including identifying barriers and facilitators to PrEP use in order to inform intervention development. Extant literature shows that despite the documented benefits of PrEP as an effective HIV-prevention method, its uptake among BMSM is limited across the U.S. South. …

Drone-Based Vibration Monitoring And Assessment Of Structures, Sabrina Carroll, Joud Satme, Shadhan Alkharusi, Nikolaos Vitzilaios, Austin Downey, Dimitris Rizos

Faculty Publications

This paper presents a novel method of procuring and processing data for the assessment of civil structures via vibration monitoring. This includes the development of a custom sensor package designed to minimize the size/weight while being fully self-sufficient (i.e., not relying on external power). The developed package is delivered to the structure utilizing a customized Unmanned Aircraft System (UAS), otherwise known as a drone. The sensor package features an electropermanent magnet for securing it to the civil structure while a second magnet is used to secure the package to the drone during flight. The novel B-Spline Impulse Response Function (BIRF) …

Pre-Exposure Prophylaxis (Prep) Uptake Among Black Men Who Have Sex With Men (Bmsm) In The Southern U.S., Oluwafemi Atanda Adeagbo, Sayward Harrison, Shan Qiao, Xiaoming Li

Faculty Publications

Black men who have sex with men (BMSM) living in the United States (U.S.) South are disproportionately affected by HIV and experience significant disparities in HIV incidence, access to HIV care, and prevention across ages and socio-economic statuses. The aim of this commentary is to critically review current literature on the state of PrEP use among BMSM in the U.S. South, including identifying barriers and facilitators to PrEP use in order to inform intervention development. Extant literature shows that despite the documented benefits of PrEP as an effective HIV-prevention method, its uptake among BMSM is limited across the U.S. South. …

Trigger Warnings In Psychology Classrooms?: Comparing Sexes From A Diverse Religious Institution, Jasmine Collard, Herbert W. Helm Jr

Faculty Publications

Sensitive, oftentimes unsettling topics are inherent, especially in psychology education (Boysen et al., 2018). Prior notification - also known as trigger warnings - to help students prepare for, or avoid, possibly disturbing, upcoming education topics (Boysen, 2017, p. 164) are being pushed for by college students on potentially disturbing content. We previously replication Guy A. Boysen’s “Trigger Warnings in psychology Classes: What Do Students Think?” and found that students from a diverse, religious institution had few significant differences, but, in general, the results from the two data sets were quite similar (Kim et al, 2020). To expand on this knowledge, …

Bamboo-Based Biofoam Adsorbents For The Adsorption Of Cationic Pollutants In Wastewater: Methylene Blue And Cu(Ii), Chongpeng Qiu, Xuelun Zhang, You Zhang, Qi Tang, Zihui Yuan, Cornelis F. De Hoop, Jiwen Cao, Shilin Hao, Ting Liang, Feng Li, Xingyan Huang

Faculty Publications

Human health is being threatened by cationic pollutants in wastewater, for example, methylene blue (MB) and Cu(II). Our research team successfully fabricated biofoam adsorbents from recycled bamboo waste that removed cationic pollutants via introducing bamboo fiber sources, i.e., bamboo fiber, bamboo α-cellulose fiber, and bamboo nanocellulose fiber, into a polyurethane (PU) foam matrix. The biofoam adsorbent with 1 g of nanocellulose (PUN1) presented high removal efficiencies for MB (95.52%) and Cu(II) (100%) in low cationic pollutant concentration aqueous solutions. The biofoam adsorbent with 1 g of bamboo fiber (PUB1) also displayed excellent removal efficiency for MB (98.61%) at pH 11. …

Temporal Geospatial Analysis Of Covid-19 Pre-Infection Determinants Of Risk In South Carolina, Tianchu Lyu, Nicole Hair, Nicholas Yell, Zhenlong Li, Shan Qiao Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Disparities and their geospatial patterns exist in morbidity and mortality of COVID-19 patients. When it comes to the infection rate, there is a dearth of research with respect to the disparity structure, its geospatial characteristics, and the pre-infection determinants of risk (PIDRs). This work aimed to assess the temporal-geospatial associations between PIDRs and COVID-19 infection at the county level in South Carolina. We used the spatial error model (SEM), spatial lag model (SLM), and conditional autoregressive model (CAR) as global models and the geographically weighted regression model (GWR) as a local model. The data were retrieved from multiple sources including …

Temporal Geospatial Analysis Of Covid-19 Pre-Infection Determinants Of Risk In South Carolina, Tianchu Lyu, Nicole L. Hair, Nicholas Yell, Zhenlong Li, Shan Qiao, Chen Liang, Xiaoming Li

Faculty Publications

Disparities and their geospatial patterns exist in morbidity and mortality of COVID-19 patients. When it comes to the infection rate, there is a dearth of research with respect to the disparity structure, its geospatial characteristics, and the pre-infection determinants of risk (PIDRs). This work aimed to assess the temporal–geospatial associations between PIDRs and COVID-19 infection at the county level in South Carolina. We used the spatial error model (SEM), spatial lag model (SLM), and conditional autoregressive model (CAR) as global models and the geographically weighted regression model (GWR) as a local model. The data were retrieved from multiple sources including …

Small Studies, Big Decisions: The Role Of Pilot/Feasibility Studies In Incremental Science And Premature Scale-Up Of Behavioral Interventions, Michael William Beets, Lauren Von Klinggraeff, Robert G. Weaver, Bridget Ryan Armstrong, Sarah Burkart

Faculty Publications

Background: Careful consideration and planning are required to establish “sufficient” evidence to ensure an investment in a larger, more well-powered behavioral intervention trial is worthwhile. In the behavioral sciences, this process typically occurs where smaller-scale studies inform larger-scale trials. Believing that one can do the same things and expect the same outcomes in a larger-scale trial that were done in a smaller-scale preliminary study (i.e., pilot/feasibility) is wishful thinking, yet common practice. Starting small makes sense, but small studies come with big decisions that can influence the usefulness of the evidence designed to inform decisions about moving forward with a …

Functions Of Social Networks In Maternal Food Choice For Children In Mexico, Ligia I. Reyes, Edward A. Frongillo, Spencer Moore, Christine E. Blake, Wendy Gonzalez, Anabelle Bonvecchio

Faculty Publications

Food choice for children has important implications in establishing early-life dietary habits and preferences. Food choice for children has been studied as parent–child dyad dynamics, but little is known about the extended system of relationships in maternal food choice for children. The objective of this study was to understand the functions of mothers' social networks in the food choices that mothers make for their children ages 1 to 5 years old in rural Mexico. In-depth interviews were conducted with 46 participants in three rural communities. The interviews inquired about participants' child-feeding practices, personal and local beliefs about child feeding and …

A Southwestern United States Pilot Investigation Of Triatomine–Mite Prevalence, Kyndall C. Dye-Braumuller, Hanna Waltz, Mary K. Lynn, Stephen A. Klotz, Justin O. Schmidt, Alvaro Romero, Marvin Stanley Rodriguez Aquino, Jose Ricardo Palacios Valladares, Pamela Michelle Cornejo Rivas, Melissa Nolan Ph.D., Mph

Faculty Publications

An estimated 70 million persons in the Western Hemisphere are living at risk for Chagas disease, a parasitic infection transmitted to humans by over 156 different competent triatomine insect vector species. Prior Pan American Health Organization insecticide campaigns throughout Latin America in the 1990s and 2000s demonstrated that domestic insecticide spraying had temporary effects, which resulted in the re-establishment of triatomine species within a few years. Serendipitously, our team found ectoparasitic mites parasitizing triatomines collected from the field in multiple locations in the southwestern United States, where human–triatomine interaction was high but human parasite infection remains low. Upon further investigation …

Maternal Resources For Care Are Associated With Child Growth And Early Childhood Development In Bangladesh And Vietnam, Sulochana Basnet, Edward A. Frongillo Jr., Phuong Hong Nguyen, Spencer Moore, Mandana Arabi

Faculty Publications

BACKGROUND:

Suboptimal child growth and development are significant problems in low- and middle-income countries. Maternal resources for care may help to improve growth and development. This study examined the association of maternal resources for care on child length, motor development and language development of children 12-23.9 months old.

METHODS:

We used baseline data from the Alive & Thrive household surveys collected in Bangladesh (n = 803) and Vietnam (n = 635). Resources for care were represented by maternal education, knowledge, height, well-nourishment, mental well-being, decision-making, employment, support in chores and perceived support. The regression analyses were adjusted for household wealth …

International Society Of Sports Nutrition Position Stand: Sodium Bicarbonate And Exercise Performance, Jozo Grgic, Zeljko Pedisic, Bryan Saunders, Guilherme G. Artioli, Brad J. Schoenfeld, Michael J. Mckenna, David J. Bishop, Richard B. Kreider, Jeffrey R. Stout, Douglas S. Kalman, Shawn M. Arent, Trisha A. Vandusseldorp, Hector L. Lopez, Tim N. Ziegenfuss, Louise M. Burke, Jose Antonio, Bill I. Campbell

Faculty Publications

Based on a comprehensive review and critical analysis of the literature regarding the effects of sodium bicarbonate supplementation on exercise performance, conducted by experts in the field and selected members of the International Society of Sports Nutrition (ISSN), the following conclusions represent the official Position of the Society:

1. Supplementation with sodium bicarbonate (doses from 0.2 to 0.5 g/kg) improves performance in muscular endurance activities, various combat sports, including boxing, judo, karate, taekwondo, and wrestling, and in high-intensity cycling, running, swimming, and rowing. The ergogenic effects of sodium bicarbonate are mostly established for exercise tasks of high-intensity that last between …

Maternal Diet In Pregnancy And Child’S Respiratory Outcomes: An Individual Participant Data Meta-Analysis Of 18 000 Children, Sara M. Mensink-Bout, Evelien R. Van Meel, Johan C. De Jongste, Isabella Annesi-Maesano, Adrien M. Aubert, Jonathan Y. Bernard, Ling-Wei Chen, Cyrus Cooper, Sarah R. Crozier, Wojciech Hanke, Nicholas C. Harvey, James R. Hébert Scd, Barbara Heude, Joanna Jerzynska, Cecily C. Kelleher, John Mehegan, Fionnuala M. Mcauliffe, Catherine M. Phillips, Kinga Polanska, Caroline L. Relton, Nitin Shivappa Mbbs, Mph, Ph.D., Matthew Suderman, Vincent W.V. Jaddoe, Liesbeth Duijts

Faculty Publications

Rationale Severe fetal malnutrition has been related to an increased risk of respiratory diseases later in life, but evidence for the association of a suboptimal diet during pregnancy with respiratory outcomes in childhood is conflicting. We aimed to examine whether a pro-inflammatory or low-quality maternal diet during pregnancy was associated with child's respiratory health.

Methods We performed an individual participant meta-analysis among 18 326 mother–child pairs from seven European birth cohorts. Maternal pro-inflammatory and low-quality diets were estimated by energy-adjusted Dietary Inflammatory Index (E-DII) and Dietary Approaches to Stop Hypertension (DASH) scores. Preschool wheezing and school-age asthma were measured using …