Digital Commons Network^™

Little Qualitative Rna Misexpression In Sterile Male F1 Hybrids Of Drosophila Pseudoobscura And D. Persimilis, Jane Reiland, Mohamed A.F. Noor

Faculty Publications

Background: Although the genetics of hybrid sterility has been the subject of evolutionary studies for over sixty years, no one has shown the reason(s) why alleles that operate normally within species fail to function in another genetic background. Several lines of evidence suggest that failures in normal gene transcription contribute to hybrid dysfunctions, but genome-wide studies of gene expression in pure-species and hybrids have not been undertaken. Here, we study genome-wide patterns of expression in Drosophila pseudoobscura, D. persimilis, and their sterile F1 hybrid males using differential display. Results: Over five thousand amplifications were analyzed, and 3312 were present in …

Comparative Proteome Analysis Of Brucella Melitensis Vaccine Strain Rev 1 And A Virulent Strain, 16m, Michel Eschenbrenner, Mary Ann Wagner, Troy A. Horn, Jo Ann Kraycer, Cesar V. Mujer, Sue Hagius, Philip Elzer, Vito G. Delvecchio

Faculty Publications

The genus Brucella consists of bacterial pathogens that cause brucellosis, a major zoonotic disease characterized by undulant fever and neurological disorders in humans. Among the different Brucella species, Brucella melitensis is considered the most virulent. Despite successful use in animals, the vaccine strains remain infectious for humans. To understand the mechanism of virulence in B. melitensis, the proteome of vaccine strain Rev 1 was analyzed by two-dimensional gel electrophoresis and compared to that of virulent strain 16M. The two strains were grown under identical laboratory conditions. Computer-assisted analysis of the two B. melitensis proteomes revealed proteins expressed in either 16M …

Active Alu Element "A-Tails": Size Does Matter, Astrid M. Roy-Engel, Abdel Halim Salem, Oluwatosin O. Oyeniran, Lisa Deininger, Dale J. Hedges, Gail E. Kilroy, Mark A. Batzer, Prescott L. Deininger

Faculty Publications

Long and short interspersed elements (LINEs and SINEs) are retroelements that make up almost half of the human genome. L1 and Alu represent the most prolific human LINE and SINE families, respectively. Only a few Alu elements are able to retropose, and the factors determining their retroposition capacity are poorly understood. The data presented in this paper indicate that the length of Alu "A-tails" is one of the principal factors in determining the retropositional capability of an Alu element. The A stretches of the Alu subfamilies analyzed, both old (Alu S and J) and young (Ya5), had a Poisson distribution …

Inhibition Of Amyloid-Β Aggregation And Caspase-3 Activation By The Ginkgo Biloba Extract Egb761, Yuan Luo, Julie V. Smith, Vijaykumar Paramasivam, Adam Burdick, Kenneth J. Curry, Justin P. Buford, Ikhlas Khan, William J. Netzer, Huaxi Xu, Peter Butko

Faculty Publications

Standardized extract from the leaves of the Ginkgo biloba tree, labeled EGb761, has been used in clinical trials for its beneficial effects on brain functions, particularly in connection with age-related dementias and Alzheimer's disease (AD). Substantial experimental evidence indicates that EGb761 protects against neuronal damage from a variety of insults, but its cellular and molecular mechanisms remain unknown. Using a neuroblastoma cell line stably expressing an AD-associated double mutation, we report that EGb761 inhibits formation of amyloid-β (Aβ) fibrils, which are the diagnostic, and possibly causative, feature of AD. The decreased Aβ fibrillogenesis in the presence of EGb761 was observed …

Evolution And Dynamics Of Tropical River Plumes In The Great Barrier Reef: An Integrated Remote Sensing And In Situ Study, D.M. Burrage, M.L. Heron, J.M. Hacker, T.C. Stieglitz, C.R. Steinberg, A. Prytz

Faculty Publications

[1] The short-lived but intense discharge of freshwater from tropical rivers into the Great Barrier Reef (GBR) Lagoon and the associated salinity reductions are a critical consideration in marine research and management of the ecologically sensitive GBR World Heritage Area. Salinity provides a unique tracer that gives clues to the origin of river-borne contaminants and allows the influences of storm-induced resuspension and river discharge on turbidity to be clearly distinguished. We describe a field investigation of the evolution and dynamics of the Herbert River plume in the central GBR. Its primary goals were to use an airborne salinity mapper and …

Integrating Marriage Education Into Perinatal Education, Alan J. Hawkins, Tamara Gilliland, Glenda Christiaens, Jason S. Carroll

Faculty Publications

Couples making the transition to parenthood experience challenges that can threaten the quality and stability of their relationships and the health of family members. Currently, the educational infrastructure to support the delivery of couple-relationship education during the transition to parenthood is limited. Because new-parent couples interact with the health care system at many points during this transition time, an opportunity exists for strengthening couple relationships within the system to improve the well-being of adults and children. in this article, we propose a productive collaboration between marriage/couple educators and health care systems to integrate couple-relationship education into the standard of perinatal …

Investigating The Mechanism Of Acoustically Activated Uptake Of Drugs From Pluronic Micelles, Ghaleb A. Husseini, Christopher M. Runyan, William G. Pitt

Faculty Publications

Background

This paper examines the mechanism of ultrasonic enhanced drug delivery from Pluronic micelles. In previous publications by our group, fluorescently labeled Pluronic was shown to penetrate HL-60 cells with and without the action of ultrasound, while drug uptake was increased with the application of ultrasound.

Methods

In this study, the amount of uptake of two fluorescent probes, Lysosensor Green (a pH-sensitive probe) and Cell Tracker Orange CMTMR (a pH-independent probe), was measured in HL-60 and HeLa cells.

Results

The results of our experiments show that the increase in drug accumulation in the cells as a result of ultrasonication is …

Leading Neutron Production In E+ P Collisions At Hera, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, A. Pellegrino, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, G. Levi, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan

Faculty Publications

The production of neutrons carrying at least 20% of the proton beam energy (xL > 0.2) in e+ p collisions has been studied with the ZEUS detector at HERA for a wide range of Q2, the photon virtuality, from photoproduction to deep inelastic scattering. The neutron-tagged cross section, ep → e′ Xn, is measured relative to the inclusive cross section, ep → e′ X, thereby reducing the systematic uncertainties. For xL > 0.3, the rate of neutrons in photoproduction is about half of that measured in hadroproduction, which constitutes a clear breaking of factorisation. There is about a 20% rise in the …

Metabotropic Glutamate Receptor 5 And Calcium Signaling In Retinal Amacrine Cells, Romina Sosa, Brian Hoffpauir, Michele L. Rankin, Richard C. Bruch, Evanna L. Gleason

Faculty Publications

To begin to understand the modulatory role of glutamate in the inner retina, we examined the mechanisms underlying metabotropic glutamate receptor 5 (mGluR5)-dependent Ca2+ elevations in cultured GABAergic amacrine cells. A partial sequence of chicken retinal mGluR5 encompassing intracellular loops 2 and 3 suggests that it can couple to both Gq and Gs. Selective activation of mGluR5 stimulated Ca2+ elevations that varied in waveform from cell to cell. Experiments using high external K+ revealed that the mGluR5-dependent Ca2+ elevations are distinctive in amplitude and time course from those engendered by depolarization. Experiments with a Ca2+-free external solution demonstrated that the …

A Metadata Approach To Preservation Of Digital Resources: The University Of North Texas Libraries' Experience, Daniel Gelaw Alemneh, Samantha K. Hastings, Cathy Hartman

Faculty Publications

Preserving long-term access to digital information resources is one of the key challenges facing libraries and information centers today. The University of North Texas (UNT) Libraries has entered into partnership agreements with federal and state agencies to ensure permanent storage and public access to a variety of government information sources. As digital resource preservation encompasses a wide variety of interrelated activities, the UNT Libraries are taking a phased approach to ensure the long-term access to its digital resources. Formulation of preservation policy and creation of preservation metadata for electronic files and digital collections are among the most important steps. This …

Effects Of Prescribed Burning On Vegetation And Fuel Loading In Three East Texas State Parks, S. Rideout, Brian P. Oswald

Faculty Publications

-This study was conducted to evaluate the initial effectiveness of prescribed burning in the ecological restoration of forests within selected parks in east Texas. Twenty-four permanent plots were installed to monitor fuel loads, overstory, sapling, seedling, shrub and herbaceous layers within bum and control units of Mission Tejas, Tyler and Village Creek state parks. Measurements were taken during the summers of 1999 and 2000. Prescribed burning was conducted between these sampling periods in early spring 2ooo. Results indicated that the current applications of prescribed burning do not significantly influence vegetation or fuels. Sustained drought, prior management practices and imposed local …

Measurement Of High-Q 2 Charged Current Cross Sections In E - P Deep Inelastic Scattering At Hera, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, G. Levi, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch

Faculty Publications

Cross sections for e - p charged current deep inelastic scattering have been measured at a centre-of-mass energy of 318 GeV with an integrated luminosity of 16.4 pb -1 using the ZEUS detector at HERA. Differential cross sections dσ/dQ 2, dσ/dx and dσ/dy are presented for Q 2 > 200 GeV 2. In addition, d 2σ/(dxdQ 2) was measured in the kinematic range 280 GeV 2 < Q 2 < 30 000 GeV 2 and 0.015 < × < 0.42. The predictions of the Standard Model agree well with the measured cross sections. The mass of the W boson, determined from a fit to dσ/dQ 2, is M W = 80.3±2.1(stat.) ± 1.2(syst.) ± 1.0(PDF) GeV. © 2002 Published by Elsevier Science B.V.

Aha Guidelines For Primary Prevention Of Cardiovascular Disease And Stroke: 2002 Update - Consensus Panel Guide To Comprehensive Risk Reduction For Adult Patients Without Coronary Or Other Atherosclerotic Vascular Diseases, Thomas A. Pearson, Steven N. Blair, Stephen R. Daniels, Robert H. Eckel, Joan M. Fair, Stephen F. Fortmann, Barry A. Franklin, Larry B. Goldstein, Philip Greenland, Scott M. Grundy, Yuling Hong, Nancy Houston-Miller, Ronald M. Lauer, Ira S. Ockene, Ralph L. Sacco, James F. Sallis, Sidney C. Smith Jr., Neil J. Stone, Kathryn A. Taubert

Faculty Publications

No abstract provided.

Ashcroft Sends Signal Of Support For Adr In Justice Dept., Richard C. Reuben, Kevin R. Kemper

Faculty Publications

In his first public comments on the issue, U.S. Attorney General John Ashcroft signaled his support for the Justice Department's longstanding commitment to the use of alternative dispute resolution options.

Towards A National Putative Father Registry Database, Mary M. Beck

Faculty Publications

This Article analyzes putative father registries and proposes federal legislation to create a national database that will enhance and connect the state and local registries. Issues and events leading to the development of registries are reviewed in Part I. Putative father registry mechanics and applicable case law are analyzed in Parts II and III.

May Harvey Rest In Peace: Lakin V. Postal Life And Casualty Company, Robert H. Jerry Ii

Faculty Publications

More than a quarter-century has passed since I entered law school as a first-year student and began what has become a career of reading, among other things, cases. I cannot even guess the number of cases I have read in the ensuing years. Most of them have been fairly ordinary, but many have been wonderful for one reason or another. Because I hope to read at least as many cases during my next twenty-five years (or more) of legal study, I am not yet ready to crown any particular case with the title of "my favorite," "the most significant," or …

Propagation Of Detonation Waves In Tubes Split From A Pde Thrust Tube, August J. Rolling, Paul I. King, Fred R. Schauer

Faculty Publications

A Pulse Detonation Engine (PDE) combusts a fuel air mixture through detonation. Existing designs require spark plugs in each separate thrust tube to ignite premixed reactants. A single thrust tube could require the spark plug to fire hundreds of times per second for long durations. This paper reports on the use of a continuously propagating detonation wave as both a thrust producer and a single ignition source for a multi-tube system. The goal was to minimize ignition complexity and increase reliability by limiting the number of ignition sources. The work includes a systematic investigation of single tube geometric effects on …

The Chinese Market: An Enigma Unraveled, Stephen F. Diamond

Faculty Publications

No abstract provided.

Income Tax Planning For Long-Term Care, David M. English

Faculty Publications

Planning for long-term involves more than the preparation of powers of attorney and counseling on possible asset transfers to qualify for Medicaid reimbursement. Steps should also be taken to make certain that the person receiving care continues to file an income tax return and does so at a minimum possible income tax cost. Practitioners should be familiar with the procedure for filing a return on behalf of an incapacitated individual. The medical expense deduction, while of little importance for most taxpayers, is critical for many elderly, particularly for those receiving long-term care. Long-term care insurance and life insurance may be …

Recent Developments Concerning Environmental Law And Agriculture, Linda A. Malone

Faculty Publications

No abstract provided.

After Ellerth: The Tangible Employment Action In Sexual Harassment Analysis, Susan Grover

Faculty Publications

In this Article, Professor Grover argues that courts too readily allow employers to avoid vicarious liability far supervisors' unlawful sexual harassment of subordinates. The Article explores the breadth of the affirmative defense first introduced in the Supreme Court's 1998 cases of Faragher v. Boca Raton and Burlington Indus., Inc. v. Ellerth. That defense clears an employer of liability for a supervisor's unlawful sexual harassment if (a) the employer exercised reasonable care to prevent and correct promptly any sexually harassing behavior, and (b) the plaintiff employee unreasonably failed to take advantage of any preventive or corrective opportunities provided by the employer …

Marbury Ascendant: The Rehnquist Court And The Power To "Say What The Law Is", Timothy Zick

Faculty Publications

No abstract provided.

The Metes And Bounds Of State Sovereign Immunity, Scott Dodson

Faculty Publications

What are the constitutional parameters of state sovereign immunity? The Court has made clear that certain provisions of Article I contain no authority for overriding state sovereign immunity, while at least one other provision, the Fourteenth Amendment, permits Congress to abrogate the states’ sovereign immunity. How is this constitutional line drawn? It is temporally bound? In other words, are only certain Amendments enacted after the Eleventh Amendment free from absolute subservience to state sovereign immunity? Or, does it divide the original Constitution and its Amendments, meaning that state sovereign immunity permeates the original Constitution but does not infiltrate certain Amendments, …

Exclusive Photoproduction Of J/Ψ Mesons At Hera, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, A. Pellegrino, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, G. Levi, A. Margotti, T. Massam, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi

Faculty Publications

The exclusive photoproduction of J/ψ mesons, γp → J/ψp, has been studied in ep collisions with the ZEUS detector at HERA, in the kinematic range 20 < W < 290 GeV, where W is the photon-proton centre-of-mass energy. The J/ψ mesons were reconstructed in the ninon and the electron decay channels using integrated luminosities of 38 pb-1 and 55 pb-1, respectively. The helicity structure of J/ψ production shows that the hypothesis of s-channel helicity conservation is satisfied within two standard deviations. The total cross section and the differential cross-section dσ/dt, where t is the squared four-momentum transfer at the proton vertex, are presented as a function of W, for |t| < 18 Ge2. The t distribution exhibits an exponential shape with a slope parameter increasing logarithmically with W with a value b = 4.15 ± 0.05(stat.)-0.18+0.30(syst.) GeV-2 at W = 90 GeV. The effective parameters of the Pomeron trajectory are αℙ(0) = 1.200 ± 0.009(stat.) -0.010+0.004(Syst.) and α′ℙ = 0.115 ± 0.018(stat.)-0.015+0.008(syst.) GeV-2.

A Young Girl With Missile Trauma Near The Eye, Renea L. Beckstrand, Ellen K. Sanders

Faculty Publications

A 15-year-old girl who came to the emergency department holding tissue to her right eye said that she had been shot. She had right eye pain and swelling below the eye, and she was bleeding. As the girl was getting off a school bus, a male occupant in a car that was driving past reached out of the passenger side window and shot multiple pellets at the school bus with a pellet gun. The shooter was unknown to the girl; the shooting seemed to be random. When the girl was shot she felt pain immediately in the area between her …

N Uptake As A Function Of Concentration In Streams, Walter K. Dodds, Amanda J. Lopez, William B. Bowden, Stan Gregory, Nancy B. Grimm, Stephen K. Hamilton, Anne E. Hershey, Eugenia Marti, William H. Mcdowell, Judy L. Meyer, Donna Morrall, Patrick J. Mulholland, Bruce J. Peterson, Jennifer L. Tank, H. Maurice Valett, Jackson R. Webster, Wilfred M. Wollheim

Faculty Publications

Detailed studies of stream N uptake were conducted in a prairie reach and gallery forest reach of Kings Creek on the Konza Prairie Biological Station. Nutrient uptake rates were measured with multiple short-term enrichments of NO3− and NH4+ at constant addition rates in the spring and summer of 1998. NH4+ uptake was also measured with 15N-NH4+ tracer additions and short-term unlabeled NH4+ additions at 12 stream sites across North America. Concurrent addition of a conservative tracer was used to account for dilution in all experiments. NH4+ uptake rate per unit area (Ut) was positively correlated to nutrient concentration across all …

Prevention Conference Vi: Diabetes And Cardiovascular Disease - Writing Group Iii: Risk Assessment In Persons With Diabetes, Rita F. Redberg, Philip Greenland, Valentin Fuster, Kalevi Pyörälä, Steven N. Blair, Aaron R. Folsom, Anne B. Newman, Daniel H. O'Leary, Trever J. Orchard, Bruce Psaty, J. Sanford Schwartz, Rodman D. Starke, Peter W. F. Wilson

Faculty Publications

No abstract provided.

Search For Lepton-Flavor Violation In E+P Collisions At Desy Hera, S. Chekanov, M. Derrick, D. Krakauer, S. Magill, B. Musgrave, A. Pellegrino, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, G. Levi, A. Margotti, T. Massam, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli

Faculty Publications

A search has been made for lepton-flavor-violating interactions of the type e+p→lX, where l denotes a μ or τ with high transverse momentum, at a center-of-mass energy √s of 300 GeV with an integrated luminosity of 47.7 pb-1 using the ZEUS detector at HERA. No evidence was found for lepton-flavor violation and constraints were derived on leptoquarks (LQs) that could mediate such interactions. For LQ masses below √s, limits are set on λeq1βlq, where λeq1 is the coupling of the LQ to an electron and a first-generation quark q1 and βlq is the branching ration of the LQ to l …

Parental Substance Use Disorder And The Risk Of Adolescent Drug Abuse: An Event History Analysis, John P. Hoffmann, Felicia G. Cerbone

Faculty Publications

A common observation in the research literature is that children of drug-dependent parents are at significantly heightened risk of adolescent drug use, abuse, and dependence. Recent research indicates that several psychological and interpersonal factors may affect the association between parents’ psychoactive substance use disorder (PSUD) and drug use risks among adolescents, yet studies have failed to examine explicitly whether these factors moderate the association between PSUD and adolescent substance abuse. This paper explores these potential relationships using longitudinal data from a study that has followed three cohorts of adolescents and their families over a 7-year period. The cohorts are defined …

Measurement Of The Photon-Proton Total Cross Section At A Center-Of-Mass Energy Of 209 Gev At Hera, S. Chekanov, M. Derrick, D. Krakauer, S. Magill, B. Musgrave, A. Pellegrino, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, G. Levi, A. Margotti, T. Massam, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli

Faculty Publications

The photon-proton total cross section has been measured in the process e+ p → e+ γp → e+ X with the ZEUS detector at HERA. Events were collected with photon virtuality Q2 < 0.02 GeV2 and average γp center-of-mass energy Wγp = 209 GeV in a dedicated run, designed to control systematic effects, with an integrated luminosity of 49 nb-1. The measured total cross section is σtotγp = 174 ± 1 (stat.) ± 13 (syst.) μb. The energy dependence of the cross section is compatible with parameterizations of high-energy pp and pap data. © 2002 Elsevier Science B.V. All rights reserved.