Digital Commons Network^™

Macrocycle-Derived Functional Xanthenes And Progress Towards Concurrent Detection Of Glucose And Fructose, Oleksandr Rusin, Onur Alpturk, Ming He, Jorge O. Escobedo, Shan Jiang, Fareed Dawan, Kun Lian, Matthew E. Mccarroll, Isiah M. Warner, Robert M. Strongin

Faculty Publications

The detection of saccharides in biological media is of great current importance for the monitoring of disease states. We have previously reported that solutions of boronic acid-functionalized macrocycles form acyclic oligomeric materials in situ. The oligomers contain fluorescent xanthene moieties. Current efforts are aimed at modulating the spectroscopic responses of these materials for the analysis of specific sugars. We describe conditions whereby the xanthene boronic acids exhibit high colorimetric fructose selectivity. In contrast, at physiological levels selective glucose monitoring can be achieved via fluorescence. Additionally, we describe a method which exhibits promise for detecting both glucose and fructose at dual …

Pharmacokinetics Of Once-Daily Amikacin In Healthy Foals And Therapeutic Drug Monitoring In Hospitalized Equine Neonates, Erica Paige Bucki, Steeve Giguère, Margo Macpherson, Rachel E. Davis

Faculty Publications

The objectives of this study were to investigate the pharmacokinetics of once-daily amikacin in healthy neonates, to determine amikacin concentrations in hospitalized foals, and to determine the minimum inhibitory concentrations (MICs) of amikacin against gram-negative isolates from blood cultures in septic foals. Median half-life, clearance, and volume of distribution of amikacin in healthy 2- to 3-day-old foals after administration of an intravenous bolus of amikacin (25 mg/kg) were 5.07 hours (4.86-5.45 hours), 1.82 mL/min/kg (1.35-1.97 mL/min/kg), and 0.785 L/kg (0.638-0.862 L/kg), respectively. Statistically significant (P or = 3 microg/mL between the 2 groups. An initial dose at 25 mg/kg is …

The Palawai Pioneers On The Island Of Lanai: The First Hawaiian Latter-Day Saint Gathering Place (1854-1864), Fred E. Woods

Faculty Publications

A decade after the death of the Prophet Joseph Smith and his brother Hyrum, the message of the Restoration continued to breathe new spiritual life into thousands who were part of scattered Israel, and the Hawaiians were no exception. The call to gather had go forth: "Gather ye out from among the nations, from the four winds, from one end of heaven to the other. Send forth my elders of my church unto the nations, which are afar off; unto the islands of the sea" (D&C 133:7-8). After the Saints had been exiled from Nauvoo in 1846 and had migrated …

Social Investigation And Rural England, 1870-1914, L. Margaret Barnett

Faculty Publications

No abstract provided.

Ministering In The Midst Of Competing Worldviews, Trevor O'Reggio

Faculty Publications

No abstract provided.

Public Sector Transition In Post-Communist Economies: The Struggle For Fiscal Decentralization In The Czech And Slovak Republics, Phillip J. Bryson, Gary C. Cornia

Faculty Publications

Transition studies have often been studies of transitioning private sectors. How centralist governments withdraw from the business of micromanaging a nation's enterprises is a fascinating story indeed. The other side of the coin, how the public sector is to be brought to decentralization and democracy, is likewise of great moment for the peoples of the transitioning countries. Under central planning the tradition was to provide all public goods and services under the direction of the central government and its ministries. There were no genuine subnational governments, since all policy decisions pertaining to taxation and the distribution of public services were …

Low Levels Of Nucleotide Diversity In Crocodylus Moreletii And Evidence Of Hybridization With C. Acutus, David A. Ray, Jennifer A. Dever, Steven G. Platt, Thomas R. Rainwater, Adam G. Finger, Scott T. Mcmurry, Mark A. Batzer, Brady Barr, Peter J. Stafford, Jenna Mcknight, Llewellyn D. Densmore

Faculty Publications

Examinations of both population genetic structure and the processes that lead to such structure in crocodilians have been initiated in several species in response to a call by the IUCN Crocodile Specialist Group. A recent study used microsatellite markers to characterize Morelet's crocodile (Crocodylus moreletii) populations in north-central Belize and presented evidence for isolation by distance. To further investigate this hypothesis, we sequenced a portion of the mitochondrial control region for representative animals after including samples from additional locales in Belize, Guatemala and Mexico. While there is limited evidence of subdivision involving other locales, we found that most of the …

Homologs Of Plant Psbp And Psbq Proteins Are Necessary For Regulation Of Photosystem Ii Activity In The Cyanobacterium Synechocystis 6803 W Inside Box Sign, Leeann E. Thomton, Hiroshi Ohkawa, Johnna L. Roose, Yasuhiro Kashino, Nir Keren, Himadri B. Pakrasi

Faculty Publications

The mechanism of oxygen evolution by photosystem II (PSII) has remained highly conserved during the course of evolution from ancestral cyanobacteria to green plants. A cluster of manganese, calcium, and chloride ions, whose binding environment is optimized by PSII extrinsic proteins, catalyzes this water-splitting reaction. The accepted view is that in plants and green algae, the three extrinsic proteins are PsbO, PsbP, and PsbQ, whereas in cyanobacteria, they are PsbO, PsbV, and PsbU. Our previous proteomic analysis established the presence of a PsbQ homolog in the cyanobacterium Synechocystis 6803. The current study additionally demonstrates the presence of a PsbP homolog …

Hydrothermal Venting In Magma Deserts: The Ultraslow-Spreading Gakkel And Southwest Indian Ridges, Edward T. Baker, Henrietta N. Edmonds, Peter J. Michael, Wolfgang Bach, Henry J.B. Dick, Jonathan E. Snow, Sharon L. Walker, Neil R. Banerjee, Charles H. Langmuir

Faculty Publications

Detailed hydrothermal surveys over ridges with spreading rates of 50-150 mm/yr have found a linear relation between spreading rate and the spatial frequency of hydrothermal venting, but the validity of this relation at slow and ultraslow ridges is unproved. Here we compare hydrothermal plume surveys along three sections of the Gakkel Ridge (Arctic Ocean) and the Southwest Indian Ridge (SWIR) to determine if hydrothermal activity is similarly distributed among these ultraslow ridge sections and if these distributions follow the hypothesized linear trend derived from surveys along fast ridges. Along the Gakkel Ridge, most apparent vent sites occur on volcanic highs, …

Increasing The Jury Pool: Impact Of The Employer Tax Credit, Paula Hannaford-Agor

Faculty Publications

To address the problem of financial hardship associated with jury service, both the California Blue Ribbon Commission on Jury System Improvement and the Task Force on Jury System Improvements proposed implementation of a tax credit to encour­age employers to pay the salaries and wages of employees who are summoned for jury service. To assess the financial impact of the proposal on California employers as well as the state budget, the Administrative Office of the Courts (AOC) un­dertook the Juror Compensation Survey to document the extent to which California employ­ers currently compensate employees while on jury service.

The completed surveys were …

Polymorphisms Within A Polymorphism: Snps In And Around A Polymorphic Alu Insertion In Intron 44 Of The Human Dystrophin Gene, Alan D. Lovell, Vania Yotova, Fengxia Xiao, Mark A. Batzer, Damian Labuda

Faculty Publications

A polymorphic Yb-type Alu insertion on Xp21.3 shows a genotypic gradient across worldwide populations. We used single strand conformational polymorphism (SSCP), denaturing high-pressure liquid chromatography (DHPLC), and sequencing to characterize the level of polymorphism within this region. Two novel polymorphic sites were found within the Alu insertion itself, and a further seven novel polymorphic sites in the 2-kb flanking region. Our results showed that while DHPLC was more sensitive than SSCP, the limitations of DHPLC included the lack of ability to distinguish between multiple alleles or safely identify mutations on a polymorphic background. We believe that this is the first …

Elemental Analysis Of Soft Plaque And Calcified Plaque Deposits From Human Coronary Arteries And Aorta, J. I. Murungi, S. Thiam, R. E. Tracy, J. W. Robinson, I. M. Warner

Faculty Publications

Twenty-five samples of soft plaque and calcified plaque deposits from human hearts or aorta were analyzed using inductively coupled plasma-mass spectrometry (ICP-MS). The determined elements were Ca, P, Na, K, Mg, Zn, Cu, Ba, Pb, Fe, Al, Si, and S. Results showed that the concentration of all elements in the soft plaque was at the micromolar level. In the calcified deposits, the concentrations of Ca and P were at least an order of magnitude higher than the soft plaque, but the other elements were at the same order of magnitude. In the calcified plaque the molar ratios of Ca/P suggested …

Mormon Growth And Practices: Christian Theological Reflections, Patrick R. Keifert

Faculty Publications

Mormonism, despite its manifest departures from orthodox Christian faith, models practices of relating faith and everyday life that can be significantly instructive for Christian congregations.

Constraints On Adaptive Evolution: The Functional Trade-Off Between Reproduction And Fast-Start Swimming Performance In The Trinidadian Guppy (Poecilia Reticulata), Cameron K. Ghalambor, David N. Reznick, Jeffrey A. Walker Phd

Faculty Publications

The empirical study of natural selection reveals that adaptations often involve trade-offs between competing functions. Because natural selection acts on whole organisms rather than isolated traits, adaptive evolution may be constrained by the interaction between traits that are functionally integrated. Yet, few attempts have been made to characterize how and when such constraints are manifested or whether they limit the adaptive divergence of populations. Here we examine the consequences of adaptive life-history evolution on locomotor performance in the live-bearing guppy. In response to increased predation from piscivorous fish, Trinidadian guppies evolve an increased allocation of resources toward reproduction. These populations …

Reappraising T.L.O.'S Special Needs Doctrine In An Era Of School-Law Enforcement Entanglement, Josh Gupta-Kagan

Faculty Publications

This essay presents one doctrinal method for lawyers to defend children accused of criminal charges in juvenile or adult court: attacking the applicability of the twenty-year old case, New Jersey v. T.L.O., to most school searches. T.L.O. based its application of a lower standard for searches of students by school officials on the presumption that firm gates separate public school from law enforcement and criminal justice institutions. Later administrative search cases inside and outside of the school context show that tee lower standard of T.L.O. depends entirely on programmatic purposes that distinguish school systems and ordinary law enforcement. Porous schoolhouse …

Culture Clash: Teaching Cultural Defenses In The Criminal Law Classroom, Susan S. Kuo

Faculty Publications

In the law school classroom, the Socratic method of legal analysis removes a dispute at issue in a given case from its sociocultural context and takes the cultural backgrounds of the parties into account only when they serve the legal argument. The language of the law commands law students to siphon off the emotional and cultural content because of the enduring belief that the law is neutral and impartial. Accordingly, cultural conflicts are deemed irrelevant to legal analysis because laws are unbiased and culture-blind. This detached outlook has been termed perpectivelessness to denote a neutral, odorless, colorless non-perspective.

This essay …

Defining Accelerometer Thresholds For Activity Intensities In Adolescent Girls, Margarita S. Treuth, Kathryn H. Schmitz, Diane J. Catellier, Robert G. Mcmurray, David M. Murray, Maria João C. A. Almeida, Scott Going, James E. Norman, Russell R. Pate

Faculty Publications

Purpose - To derive a regression equation that estimates metabolic equivalent (MET) from accelerometer counts, and to define thresholds of accelerometer counts that can be used to delineate sedentary, light, moderate, and vigorous activity.

Methods - Seventy-four healthy 8th grade girls, age 13-14 yr, were recruited from urban areas of Baltimore, MD, Minneapolis/St. Paul, MN, and Columbia, SC, to participate in the study. Accelerometer and oxygen consumption (VO₂) data for 10 activities that varied in intensity from sedentary (e.g., TV watching) to vigorous (e.g., running) were collected. While performing these activities, the girls wore two accelerometers, a heart …

A Patch Hath Smaller Patches: Delineating Ecological Neighborhoods For Parasites, Derek Zelmer, John R. Seed

Faculty Publications

Use of the host individual as a boundary for parasite populations and communities provides an unambiguous spatial unit that is useful for pattern description, but this framework precludes consideration of the host landscape and within-host population dynamics. Recognizing host individuals as spatially and temporally complex landscapes requires modified concepts of parasite populations and communities. An outline of the currently accepted hierarchies of parasite populations and communities is provided on the basis of ecological neighborhoods that are delineated by discrete habitat patches or functional dynamics (or both), as opposed to host individuals. This parasite-based framework accommodates consideration of both within- and …

From Discussion Leader To Consumer Guide: A Century Of Theater Criticism In Chicago Newspapers, Scott B. Fosdick

Faculty Publications

This article completes a three-part examination of theater critics working for Chicago newspapers during the twentieth century. The first article in the series covered the "boomtown" period leading up to World War I, and the second article addressed Chicago's rise after 1960 as a regional center for theater covered by fewer newspapers and fewer critics. This article reviews those periods but emphasizes the middle, "road town" period, which saw a gradually dwindling band of critics functioning as quality control experts, passing judgment on New York road shows. After examining that period, this article uses commodification to consider the changing role …

Bottom Photoproduction Measured Using Decays Into Muons In Dijet Events In Ep Collisions At √S=318 Gev, S. Chekanov, M. Derrick, D. Krakauer, J. H. Loizides, S. Magill, S. Miglioranzi, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, A. Montanari, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli

Faculty Publications

The photoproduction of bottom quarks in events with two jets and a muon has been measured with the ZEUS detector at HERA using an integrated luminosity of 110 pb-1. The fraction of jets containing b quarks was extracted from the transverse momentum distribution of the muon relative to the closest jet. Differential cross sections for bottom production as a function of the transverse momentum and pseudorapidity of the muon, of the associated jet and of xγjets, the fraction of the photon's momentum participating in the hard process, are compared with MC models and QCD predictions made at next-to-leading order. The …

After The Flames A New Andrews University/Benton Harbor Partnership, Joseph Warren

Faculty Publications

No abstract provided.

Politics Of Embryonic Discourse, Kevin Quinn

Faculty Publications

In our brave new world of stem cells, clones, and parthenotes, how should we talk about early human embryos? In fashioning a response to this very thorny question, Ann Kiessling has a core message. It is: (1)that new science produces "new" conceptuses;(2) that science and scientists have failed to differentiate (with appropriate clarity) these new ex vivo conceptuses from those createdin vivo; (3) that new, more appropriate and scientifically-informed, terms are necessary; and (4) that this new language should transform the public discourse about human embryos. No one would deny that the subtleties of human embryology are neglected in public …

Learning Nursing Research Through Faculty-Mentored Projects, Patricia K. Ravert, Ben Boyer, Kirsten Harmon, Holly Scoffield

Faculty Publications

Baccalaureate nursing educators have incorporated nursing research content into the curriculum for many years. Our university also proposes that students have a faculty-mentored learning experience at least once during their undergraduate education. Student research, guided by a faculty mentor, provides an excellent opportunity for students to learn about and participate in nursing research. The authors describe a unique experience of nursing students working as research assistants in a faculty research project using a human patient simulator.

The Constitutionality Of The Filibuster, Michael J. Gerhardt

Faculty Publications

No abstract provided.

Judicial Dialogue For Legal Multiculturalism, Charles H. Koch Jr.

Faculty Publications

No abstract provided.

Sts Task Force On Information Literacy For Science And Technology, Virginia Baldwin, Sheila Young, Ibironke Lawal, Catherine Wong

Faculty Publications

No abstract provided.

Photoproduction Of D*± Mesons Associated With A Leading Neutron, S. Chekanov, M. Derrick, D. Krakauer, J. H. Loizides, S. Magill, S. Miglioranzi, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, A. Montanari, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli

Faculty Publications

The photoproduction of D*±(2010) mesons associated with a leading neutron has been observed with the ZEUS detector in ep collisions at HERA using an integrated luminosity of 80 pb-1. The neutron carries a large fraction, xL>0.2, of the incoming proton beam energy and is detected at very small production angles, θn< 0.8 mrad, an indication of peripheral scattering. The D* meson is centrally produced with pseudorapidity η1.9 GeV, which is large compared to the average transverse momentum of the neutron of 0.22 GeV. The ratio of neutron-tagged to inclusive D* production is 8.85±0.93(stat.) +0.48-0.61(syst.)% in the photon-proton center-of-mass energy range 130

Exceptional Record Of Mid-Pleistocene Vertebrates Helps Differentiate Climatic From Anthropogenic Ecosystem Perturbations, Anthony D. Barnosky, Christopher J. Bell, Steven D, Emslie, H. Thomas Goodwin, Jim I. Mead, Charles A. Repenning, Eric Scott, Alan B. Shabel

Faculty Publications

Mid-Pleistocene vertebrates in North America are scarce but important for recognizing the ecological effects of climatic change in the absence of humans. We report on a uniquely rich mid-Pleistocene vertebrate sequence from Porcupine Cave, Colorado, which records at least 127 species and the earliest appearances of 30 mammals and birds. By analyzing >20,000 mammal fossils in relation to modern species and independent climatic proxies, we determined how mammal communities reacted to presumed glacial-interglacial transitions between 1,000,000 and 600,000 years ago. We conclude that climatic warming primarily affected mammals of lower trophic and size categories, in contrast to documented human impacts …

Use Of Collaborative Learning Exercises To Increase Student Motivation And Learning In An Introduction To Materials Engineering Course, Stacy Gleixner, Hilary Lackritz

Faculty Publications

A collection of collaborative, in-class exercises have been designed for use in a freshmen/sophomore level Introduction to Materials Science and Engineering class. The activities are team based problems that include open ended design problems, calculation questions, and thought problems on unanswered research questions. The activities have been designed with the goal of having one or two a week embedded in a more traditional lecture setting. The exercises relate to the topics covered in most standard Introduction to Materials classes (crystal structure, mechanical properties, polymers, phase diagrams…). Each activity is designed specifically to engage the students in the lecture and excite …

A Physiochemically Constrained Seawater Culturing System For Production Of Benthic Foraminifera, Christopher J. Hintz, G. Thomas Chandler, Jay M. Bernhardt, Daniel C. Mccorkle, Suzanne M. Havach, Jessica K. Blanks, Timothy J. Shaw

Faculty Publications

No abstract provided.