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Articles 91 - 120 of 223
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Instrumental- And Emotion-Focused Care Work During Physical Health Events: Comparing Gay, Lesbian, And Heterosexual Marriages, Debra Umberson, Mieke Beth Thomeer, Rhiannon A. Kroeger, Corinne Reczek, Rachel Donnelly
Instrumental- And Emotion-Focused Care Work During Physical Health Events: Comparing Gay, Lesbian, And Heterosexual Marriages, Debra Umberson, Mieke Beth Thomeer, Rhiannon A. Kroeger, Corinne Reczek, Rachel Donnelly
Faculty Publications
Objectives: We consider emotion- and instrumental-focused care work and marital stress during significant physical health events in midlife gay, lesbian, and heterosexual marriages. Method: We employ the factorial method, an extension of the actor-partner interdependence model, to analyze survey data from 808 midlife gay, lesbian, and heterosexual spouses in 404 unions. Results: The amount of emotion- and instrumental-focused care work provided during physical health events, and the associations between care work and marital stress, depends on the gender of the respondent, gender of the spouse, and whether spouses are in a same-sex or different-sex union. For example, in both same- …
Psychological Resilience Can Help Combat The Effect Of Stress On Problematic Social Networking Site Usage, Xiang-Ling Hou, Hai-Zhen Wang, Cheng Guo, James Gaskin, Detlef H. Rost, Jin-Liang Wang
Psychological Resilience Can Help Combat The Effect Of Stress On Problematic Social Networking Site Usage, Xiang-Ling Hou, Hai-Zhen Wang, Cheng Guo, James Gaskin, Detlef H. Rost, Jin-Liang Wang
Faculty Publications
This study was aimed to test the association between perceived stress and problematic social networking site (SNS) usage, and to figure outwhether psychological resiliencemoderated this relationship. The Perceived Stress Scale, Connor-Davidson Resilience Scale, and Facebook Intrusion Questionnaire were administered to 499 Chinese college students. The results showed that (1) perceived stress was positively associated with problematic SNS usage; (2) psychological resiliencewas negatively relatedwith problematic SNS usage; and (3) psychological resilience moderated the relationship between perceived stress and problematic SNS usage. Specifically, the relationship between perceived stress and problematic SNS usage was statistically significant for students with a lower level of …
Reliability Of Doming And Toe Flexion Testing To Quantify Foot Muscle Strength, Sarah T. Ridge, J. William Myrer, Mark T. Olsen, Kevin Jurgensmeier, A. Wayne Johnson
Reliability Of Doming And Toe Flexion Testing To Quantify Foot Muscle Strength, Sarah T. Ridge, J. William Myrer, Mark T. Olsen, Kevin Jurgensmeier, A. Wayne Johnson
Faculty Publications
Quantifying the strength of the intrinsic foot muscles has been a challenge for clinicians and researchers. The reliable measurement of this strength is important in order to assess weakness, which may contribute to a variety of functional issues in the foot and lower leg, including plantar fasciitis and hallux valgus. This study reports 3 novel methods for measuring foot strength – doming (previously unmeasured), hallux flexion, and flexion of the lesser toes.
Meta-Analysis Of 49 549 Individuals Imputed With The 1000 Genomes Project Reveals An Exonic Damaging Variant In Angptl4 Determining Fasting Tg Levels, Elisabeth M. Van Leeuwen, Aniko Sabo, Joshua C. Bis, Jennifer E. Huffman, Ani Manichaikul, Albert V. Smith, Mary F. Feitosa, Serkalem Demissie, Peter K. Joshi, Qing Duan, Jonathan Marten, Jan B. Van Klinken, Ida Surakka, Ilja M. Nolte, Weihua Zhang, Hamdi Mbarek, Ruifang Li-Gao, Stella Trompet, Niek Verweij, Evangelos Evangelou, Leo Pekka Lyytikäinen, Bamidele O. Tayo, Joris Deelen, Peter J. Van Der Most, Sander W. Van Der Laan, Dan E. Arking, Alanna Morrison, Abbas Dehghan, Oscar H. Franco, Albert Hofman, Fernando Rivadeneira, Eric J. Sijbrands, Andre G. Uitterlinden
Meta-Analysis Of 49 549 Individuals Imputed With The 1000 Genomes Project Reveals An Exonic Damaging Variant In Angptl4 Determining Fasting Tg Levels, Elisabeth M. Van Leeuwen, Aniko Sabo, Joshua C. Bis, Jennifer E. Huffman, Ani Manichaikul, Albert V. Smith, Mary F. Feitosa, Serkalem Demissie, Peter K. Joshi, Qing Duan, Jonathan Marten, Jan B. Van Klinken, Ida Surakka, Ilja M. Nolte, Weihua Zhang, Hamdi Mbarek, Ruifang Li-Gao, Stella Trompet, Niek Verweij, Evangelos Evangelou, Leo Pekka Lyytikäinen, Bamidele O. Tayo, Joris Deelen, Peter J. Van Der Most, Sander W. Van Der Laan, Dan E. Arking, Alanna Morrison, Abbas Dehghan, Oscar H. Franco, Albert Hofman, Fernando Rivadeneira, Eric J. Sijbrands, Andre G. Uitterlinden
Faculty Publications
Background So far, more than 170 loci have been associated with circulating lipid levels through genomewide association studies (GWAS). These associations are largely driven by common variants, their function is often not known, and many are likely to be markers for the causal variants. In this study we aimed to identify more new rare and low-frequency functional variants associated with circulating lipid levels. Methods We used the 1000 Genomes Project as a reference panel for the imputations of GWAS data from ~60 000 individuals in the discovery stage and ~90 000 samples in the replication stage. Results Our study resulted …
Ubisol-Q10 Prevents Glutamate-Induced Cell Death By Blocking Mitochondrial Fragmentation And Permeability Transition Pore Opening, Santosh Kumari, Suresh L. Mehta, Gaolin Z. Milledge, Xinyu Huang, P Andy Li
Ubisol-Q10 Prevents Glutamate-Induced Cell Death By Blocking Mitochondrial Fragmentation And Permeability Transition Pore Opening, Santosh Kumari, Suresh L. Mehta, Gaolin Z. Milledge, Xinyu Huang, P Andy Li
Faculty Publications
Mitochondrial dysfunction and oxidative stress are the major events that lead to the formation of mitochondrial permeability transition pore (mPTP) during glutamate-induced cytotoxicity and cell death. Coenzyme Q10 (CoQ10) has widely been used for the treatment of mitochondrial disorders and neurodegenerative diseases. Comparing to traditional lipid-soluble CoQ10, water soluble CoQ10 (Ubisol-Q10) has high intracellular and intra-mitochondrial distribution. The aims of the present study are to determine the neuroprotective effects of Ubisol-Q10 on glutamate-induced cell death and to explore its functional mechanisms. HT22 neuronal cells were exposed to glutamate. Cell viability was measured and mitochondrial fragmentation was assessed by mitochondrial imaging. …
Amending The Uniform Guardianship And Protective Proceedings Act To Implement The Standards And Recommendations Of The Third National Guardianship Summit, David M. English
Amending The Uniform Guardianship And Protective Proceedings Act To Implement The Standards And Recommendations Of The Third National Guardianship Summit, David M. English
Faculty Publications
The Third National Guardianship Summit, which was held in 2011, recommended the adoption of 70 standards and recommendations relating to guardianship law and practice. This article analyzes the standards and recommendations that might best be implemented by statutory change. The article focuses in particular on how the standards and recommendations might be applied in the current project to amend the Uniform Guardianship and Protective Proceedings Act (UGPPA), various versions of which have been enacted in numerous states.
Insomnia Is Associated With Suicide Attempt In Middle-Aged And Older Adults With Depression, Daniel Kay, Alexandre Y. Dombrovski, Daniel J. Buysse, Charles F. Reynolds Iii, Amy Begley, Katalin Szanto
Insomnia Is Associated With Suicide Attempt In Middle-Aged And Older Adults With Depression, Daniel Kay, Alexandre Y. Dombrovski, Daniel J. Buysse, Charles F. Reynolds Iii, Amy Begley, Katalin Szanto
Faculty Publications
Background—Insomnia increases in prevalence with age, is strongly associated with depression, and has been identified as a risk factor for suicide in several studies. The aim of this study was to determine whether insomnia severity varies between those who have attempted suicide (n = 72), those who only contemplate suicide (n = 28), and those who are depressed but have no suicidal ideation or attempt history (n = 35).
Methods—Participants were middle-aged and older adults (Age 44–87, M = 66 years) with depression. Insomnia severity was measured as the sum of the early, middle, and late insomnia items from the …
Sleep In The Context Of Healthy Aging And Psychiatric Syndromes, Daniel Kay, Joseph M. Dzierzewski
Sleep In The Context Of Healthy Aging And Psychiatric Syndromes, Daniel Kay, Joseph M. Dzierzewski
Faculty Publications
Humans spend approximately 1/3 of their lives asleep. Whether due to evolutionary or ontogenetic factors, sleep and psychiatric disorders change with age. While much of sleep remains an enigma, the field of sleep research is experiencing an exponential increase in its understanding of the causes, correlates, and consequences of sleep disturbances. Although the relationship between age-related sleep and psychiatric conditions is a common clinical observation, empirical investigations into these associations remain scarce. Thus, treating patients with symptoms of sleep disorders in the context of psychiatric conditions remains a major challenge. This chapter reviews the state-of-the-science of sleep disorders in the …
Attitudes And Experiences With Older Adults: A Case For Service Learning For Undergraduates, Hardeep Obhi, Erin Woodhead
Attitudes And Experiences With Older Adults: A Case For Service Learning For Undergraduates, Hardeep Obhi, Erin Woodhead
Faculty Publications
The current study examined whether relationship quality with older adults currently and in childhood, as well as experience with older adults, was associated with biases toward older adults and interest in working with older adults as a possible career area. The authors sampled undergraduate students (N = 753, M = 18.97 years, SD = 2.11 years) from a Northern California university. In hierarchical regression analyses, higher perceived quality of relationships with older adult family members, higher perceived social support, and lower perceived conflict from relationships with older adults was significantly associated with positive attitudes toward older adults. Interest in …
A 360 Degree View Of Roles And Responsibilities Concerning Diminished Capacity: Financial Advisers’ Obligations To Clients, Lawyers Representing Clients, And Lawyers Preparing Their Practices, Elissa Germaine, Nicole G. Iannarone, Teresa Verges
A 360 Degree View Of Roles And Responsibilities Concerning Diminished Capacity: Financial Advisers’ Obligations To Clients, Lawyers Representing Clients, And Lawyers Preparing Their Practices, Elissa Germaine, Nicole G. Iannarone, Teresa Verges
Faculty Publications
(Excerpt)
Aging is inevitable and impacts everyone. The risk of a person developing cognitive impairment or some other incapacity affecting daily life increases with each passing year. While some will live long lives without suffering from cognitive decline, others will not be so fortunate. One thing is clear: seniors have the greatest risk of developing some form of impairment that will impact their ability to make their own decisions and that will put them at risk of fraud by predators or of harm by well-intentioned but ill-informed persons seeking to help them. As lawyers representing clients in FINRA proceedings, PIABA …
What Mediates The Relationship Between Religious Service Attendance And Aspects Of Well-Being?, Scott A. Baldwin, Patrick R. Steffen, Kevin S. Masters
What Mediates The Relationship Between Religious Service Attendance And Aspects Of Well-Being?, Scott A. Baldwin, Patrick R. Steffen, Kevin S. Masters
Faculty Publications
Religious service attendance predicts increased well-being across a number of studies. It is not clear, however, whether this relationship is due to religious factors such as intrinsic religiosity or due to nonreligious factors such as social support or socially desirable responding. The purpose of the present study was to examine the relationship between religious service attendance and well-being while simultaneously examining intrinsic religiosity, social support, and socially desirable responding as potential mediators of the relationship. A sample of 855 participants (71 % female, average age 19.5) completed questionnaires assessing religiosity, social support, socially desirable responding, and well-being. Path models were …
Gender And Attitudes About Mental Health Help Seeking: Results From National Data, Douglas Wendt, Kevin Shafer
Gender And Attitudes About Mental Health Help Seeking: Results From National Data, Douglas Wendt, Kevin Shafer
Faculty Publications
Men often express less emotion than women do, are hesitant to express weakness, and seek professional help much less frequently than do their female counterparts. The lack of help seeking is common across characteristics such as age, race, ethnicity, and nationality. Authors used data from the 2006 General Social Surveys mental health module to suggest that the gender gap in help seeking may be rooted in attitudes regarding help-seeking behaviors generally. Using structural equation modeling, we linked vignette type (depression and schizophrenia) to the endorsement of help seeking from informal and formal sources. Men showed similar support for informal help …
Mathematics Library News 14, Aaron Lercher
Special Needs Children And Mental Health, Nancy J. Carbonell
Special Needs Children And Mental Health, Nancy J. Carbonell
Faculty Publications
What do these stories have in common? They are representative of many students who experience learning difficulties while at the same time struggling with mental or emotional issues. Special-needs teachers see children like Brandon, Carmen, and Jake in their classrooms every day. It is estimated that in the U.S., 37 percent of children with special needs also need mental-health care. That is approximately one in every three special-needs students! This is particularly challenging for teachers whose training did not include how to deal with children experiencing mental-health issues.
Fetal Programming In Meat Production, Min Du, Bo Wang, Xing Fu, Qiyuan Yang, Mei Jun Zhu
Fetal Programming In Meat Production, Min Du, Bo Wang, Xing Fu, Qiyuan Yang, Mei Jun Zhu
Faculty Publications
© 2015 Elsevier Ltd. Nutrient fluctuations during the fetal stage affects fetal development, which has long-term impacts on the production efficiency and quality of meat. During the early development, a pool of mesenchymal progenitor cells proliferate and then diverge into either myogenic or adipogenic/fibrogenic lineages. Myogenic progenitor cells further develop into muscle fibers and satellite cells, while adipogenic/fibrogenic lineage cells develop into adipocytes, fibroblasts and resident fibro-adipogenic progenitor cells. Enhancing the proliferation and myogenic commitment of progenitor cells during fetal development enhances muscle growth and lean production in offspring. On the other hand, promoting the adipogenic differentiation of adipogenic/fibrogenic progenitor …
Directional Dominance On Stature And Cognition In Diverse Human Populations, Peter K. Joshi, Tonu Esko, Hannele Mattsson, Niina Eklund, Ilaria Gandin, Teresa Nutile, Anne U. Jackson, Claudia Schurmann, Albert V. Smith, Weihua Zhang, Yukinori Okada, Alena Stančáková, Jessica D. Faul, Wei Zhao, Traci M. Bartz, Maria Pina Concas, Nora Franceschini, Stefan Enroth, Veronique Vitart, Stella Trompet, Xiuqing Guo, Daniel I. Chasman, Jeffrey R. O'Connel, Tanguy Corre, Suraj S. Nongmaithem, Yuning Chen, Massimo Mangino, Daniela Ruggiero, Michela Traglia, Aliki Eleni Farmaki, Tim Kacprowski, Andrew Bjonnes, Ashley Van Der Spek
Directional Dominance On Stature And Cognition In Diverse Human Populations, Peter K. Joshi, Tonu Esko, Hannele Mattsson, Niina Eklund, Ilaria Gandin, Teresa Nutile, Anne U. Jackson, Claudia Schurmann, Albert V. Smith, Weihua Zhang, Yukinori Okada, Alena Stančáková, Jessica D. Faul, Wei Zhao, Traci M. Bartz, Maria Pina Concas, Nora Franceschini, Stefan Enroth, Veronique Vitart, Stella Trompet, Xiuqing Guo, Daniel I. Chasman, Jeffrey R. O'Connel, Tanguy Corre, Suraj S. Nongmaithem, Yuning Chen, Massimo Mangino, Daniela Ruggiero, Michela Traglia, Aliki Eleni Farmaki, Tim Kacprowski, Andrew Bjonnes, Ashley Van Der Spek
Faculty Publications
Homozygosity has long been associated with rare, often devastating, Mendelian disorders, and Darwin was one of the first to recognize that inbreeding reduces evolutionary fitness. However, the effect of the more distant parental relatedness that is common in modern human populations is less well understood. Genomic data now allow us to investigate the effects of homozygosity on traits of public health importance by observing contiguous homozygous segments (runs of homozygosity), which are inferred to be homozygous along their complete length. Given the low levels of genome-wide homozygosity prevalent in most human populations, information is required on very large numbers of …
A Meta-Analysis Of Gene Expression Signatures Of Blood Pressure And Hypertension, Tianxiao Huan, Tõnu Esko, Marjolein J. Peters, Luke C. Pilling, Katharina Schramm, Claudia Schurmann, Brian H. Chen, Chunyu Liu, Roby Joehanes, Andrew D. Johnson, Chen Yao, Sai Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G. Uitterlinden, Dena G. Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger
A Meta-Analysis Of Gene Expression Signatures Of Blood Pressure And Hypertension, Tianxiao Huan, Tõnu Esko, Marjolein J. Peters, Luke C. Pilling, Katharina Schramm, Claudia Schurmann, Brian H. Chen, Chunyu Liu, Roby Joehanes, Andrew D. Johnson, Chen Yao, Sai Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G. Uitterlinden, Dena G. Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger
Faculty Publications
Genome-wide association studies (GWAS) have uncovered numerous genetic variants (SNPs) that are associated with blood pressure (BP). Genetic variants may lead to BP changes by acting on intermediate molecular phenotypes such as coded protein sequence or gene expression, which in turn affect BP variability. Therefore, characterizing genes whose expression is associated with BP may reveal cellular processes involved in BP regulation and uncover how transcripts mediate genetic and environmental effects on BP variability. A meta-analysis of results from six studies of global gene expression profiles of BP and hypertension in whole blood was performed in 7017 individuals who were not …
New Genetic Loci Link Adipose And Insulin Biology To Body Fat Distribution, D. Shungin, T. W. Winkler, D. C. Croteau-Chonka, T. Ferreira, A. E. Locke, R. Mägi, R. J. Strawbridge, T. H. Pers, K. Fischer, A. E. Justice, T. Workalemahu, J. M.W. Wu, M. L. Buchkovich, N. L. Heard-Costa, T. S. Roman, A. W. Drong, C. Song, S. Gustafsson, F. R. Day, T. Esko, T. Fall, Z. Kutalik, J. Luan, J. C. Randall, A. Scherag, S. Vedantam, A. R. Wood, J. Chen, R. Fehrmann, J. Karjalainen, B. Kahali, C. T. Liu, E. M. Schmidt
New Genetic Loci Link Adipose And Insulin Biology To Body Fat Distribution, D. Shungin, T. W. Winkler, D. C. Croteau-Chonka, T. Ferreira, A. E. Locke, R. Mägi, R. J. Strawbridge, T. H. Pers, K. Fischer, A. E. Justice, T. Workalemahu, J. M.W. Wu, M. L. Buchkovich, N. L. Heard-Costa, T. S. Roman, A. W. Drong, C. Song, S. Gustafsson, F. R. Day, T. Esko, T. Fall, Z. Kutalik, J. Luan, J. C. Randall, A. Scherag, S. Vedantam, A. R. Wood, J. Chen, R. Fehrmann, J. Karjalainen, B. Kahali, C. T. Liu, E. M. Schmidt
Faculty Publications
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, we conducted genome-wide association meta-analyses of waist and hip circumference-related traits in up to 224,459 individuals. We identified 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (WHRadjBMI) and an additional 19 loci newly associated with related waist and hip circumference measures (P<5×10-8). Twenty of the 49 WHRadjBMI loci showed significant sexual dimorphism, 19 of which displayed a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation, and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.
Genetic Studies Of Body Mass Index Yield New Insights For Obesity Biology, A. E. Locke, B. Kahali, S. I. Berndt, A. E. Justice, T. H. Pers, F. R. Day, C. Powell, S. Vedantam, M. L. Buchkovich, J. Yang, D. C. Croteau-Chonka, T. Esko, T. Fall, T. Ferreira, S. Gustafsson, Z. Kutalik, J. Luan, R. Mägi, J. C. Randall, T. W. Winkler, A. R. Wood, T. Workalemahu, J. D. Faul, J. A. Smith, J. H. Zhao, W. Zhao, J. Chen, R. Fehrmann, K. Hedman, J. Karjalainen, E. M. Schmidt, D. Absher, N. Amin
Genetic Studies Of Body Mass Index Yield New Insights For Obesity Biology, A. E. Locke, B. Kahali, S. I. Berndt, A. E. Justice, T. H. Pers, F. R. Day, C. Powell, S. Vedantam, M. L. Buchkovich, J. Yang, D. C. Croteau-Chonka, T. Esko, T. Fall, T. Ferreira, S. Gustafsson, Z. Kutalik, J. Luan, R. Mägi, J. C. Randall, T. W. Winkler, A. R. Wood, T. Workalemahu, J. D. Faul, J. A. Smith, J. H. Zhao, W. Zhao, J. Chen, R. Fehrmann, K. Hedman, J. Karjalainen, E. M. Schmidt, D. Absher, N. Amin
Faculty Publications
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10-8), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20 % of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.
Dairy Consumption And Insulin Resistance: The Role Of Body Fat, Physical Activity, And Energy Intake, Larry A. Tucker, Andrea Erickson, James D. Lecheminant, Bruce W. Bailey
Dairy Consumption And Insulin Resistance: The Role Of Body Fat, Physical Activity, And Energy Intake, Larry A. Tucker, Andrea Erickson, James D. Lecheminant, Bruce W. Bailey
Faculty Publications
The relationship between dairy consumption and insulin resistance was ascertained in 272 middle-aged, nondiabetic women using a cross-sectional design. Participants kept 7-day, weighed food records to report their diets, including dairy intake. Insulin resistance was assessed using the homeostatic model assessment (HOMA). The Bod Pod was used to measure body fat percentage, and accelerometry for 7 days was used to objectively index physical activity. Regression analysis was used to determine the extent to which mean HOMA levels differed across low, moderate, and high dairy intake categories. Results showed that women in the highest quartile of dairy consumption had significantly greater …
Prowashonupana Barley Dietary Fibre Reduces Body Fat And Increases Insulin Sensitivity In Caenorhabditis Elegans Model, Chenfei Gao, Michael L. King, Zachary L. Fitzpatrick, Wenqian Wei, Jason F. King, Mingming Wang, Frank L. Greenway, John W. Finley, Jeffrey H. Burton, William D. Johnson, Michael J. Keenan, Frederick M. Enright, Roy J. Martin, Jolene Zheng
Prowashonupana Barley Dietary Fibre Reduces Body Fat And Increases Insulin Sensitivity In Caenorhabditis Elegans Model, Chenfei Gao, Michael L. King, Zachary L. Fitzpatrick, Wenqian Wei, Jason F. King, Mingming Wang, Frank L. Greenway, John W. Finley, Jeffrey H. Burton, William D. Johnson, Michael J. Keenan, Frederick M. Enright, Roy J. Martin, Jolene Zheng
Faculty Publications
© 2015 Elsevier Ltd. Prowashonupana barley (PWB) is high in β-glucan with moderate content of resistant starch. PWB reduced intestinal fat deposition (IFD) in wild type Caenorhabditis elegans (C. elegans, N2), and in sir-2.1 or daf-16 null mutants, and sustained a surrogate marker of lifespan, pharyngeal pumping rate (PPR), in N2, sir-2.1, daf-16, or daf-16/daf-2 mutants. Hyperglycaemia (2% glucose) reversed or reduced the PWB effect on IFD in N2 or daf-16/daf-2 mutants with a sustained PPR. mRNA expression of cpt-1, cpt-2, ckr-1, and gcy-8 were dose-dependently reduced in N2 or daf-16 mutants, elevated in daf-16/daf-2 mutants with reduction in cpt-1, …
Development And Evaluation Of A Geriatric Mood Management Program, J.W. Huh, Erin Woodhead, Sarah Brunskill, Christine Gould, Kathleen Mcconnell, J. Lisa Tenover
Development And Evaluation Of A Geriatric Mood Management Program, J.W. Huh, Erin Woodhead, Sarah Brunskill, Christine Gould, Kathleen Mcconnell, J. Lisa Tenover
Faculty Publications
To address the needs of older veterans with mood disorders, the VA Palo Alto Health Care System Geriatric Research Education and Clinical Center developed a program that offers mental health services delivered by geriatrics-trained providers.
Reducing Cardiovascular Disease Risk In Mid-Life And Older African Americans: A Church-Based Longitudinal Intervention Project At Baseline, Penny A. Ralston, Jennifer L. Lemacks, Kandauda (.K.A.S.). Wickrama, Iris Young-Clark, Catherine Coccia, Jasminka Z. Ilich, Cynthia M. Harris, Celeste B. Hart, Arrie M. Battle, Catherine Walker O'Neal
Reducing Cardiovascular Disease Risk In Mid-Life And Older African Americans: A Church-Based Longitudinal Intervention Project At Baseline, Penny A. Ralston, Jennifer L. Lemacks, Kandauda (.K.A.S.). Wickrama, Iris Young-Clark, Catherine Coccia, Jasminka Z. Ilich, Cynthia M. Harris, Celeste B. Hart, Arrie M. Battle, Catherine Walker O'Neal
Faculty Publications
Introduction: African Americans (AAs) experience higher age-adjusted morbidity and mortality than Whites for cardiovascular disease (CVD). Church-based health programs can reduce risk factors for CVD, including elevated blood pressure [BP], excess body weight, sedentary lifestyle and diet. Yet few studies have incorporated older adults and longitudinal designs.
Purposes: The aims of this study are to: a) describe a theory-driven longitudinal intervention study to reduce CVD risk in mid-life and older AAs; b) compare selected dietary (fruit and vegetable servings/day, fat consumption), physical activity (PA) and clinical variables (BMI, girth circumferences, systolic and diastolic BP, LDL, HDL, total cholesterol …
Role Modeling Clinical Judgment For An Unfolding Older Adult Simulation, Kathie Lasater, Elizabeth A. Johnson, Patricia K. Ravert, Doris Rink
Role Modeling Clinical Judgment For An Unfolding Older Adult Simulation, Kathie Lasater, Elizabeth A. Johnson, Patricia K. Ravert, Doris Rink
Faculty Publications
Nurse educators must foster development of clinical judgment in students to help them provide the best care for the increasing population of older adult patients. This article reports qualitative findings from a mixed-methods study that focused on clinical judgment in the simulated perioperative care of an older adult. The sample was composed of treatment and control groups of prelicensure students (N = 275) at five sites. The treatment group watched a video of an expert nurse role model caring for a patient similar to the simulation patient, whereas the control group did not watch the video. Four weeks after simulation, …
Health Insurance Status, Psychological Processes, And Older African Americans' Use Of Preventive Care, Catherine Walker O'Neal, Kandauda A.S. Wickrama, Penny A. Ralston, Jasminka Z. Elich, Cynthia M. Harris, Catherine Coccia, Iris Young-Clark, Jennifer Lemacks
Health Insurance Status, Psychological Processes, And Older African Americans' Use Of Preventive Care, Catherine Walker O'Neal, Kandauda A.S. Wickrama, Penny A. Ralston, Jasminka Z. Elich, Cynthia M. Harris, Catherine Coccia, Iris Young-Clark, Jennifer Lemacks
Faculty Publications
The current study examined the influence of health insurance, psychological processes (i.e. psychological competency and vulnerability), and the interaction of these two constructs on older African Americans' utilization of five preventive care services (e.g. cholesterol screening and mammogram/prostate examination) using data from 211 older African Americans (median age = 60). In addition to direct effects, the influence of health insurance sometimes varied depending on respondents' psychological competency and/or vulnerability. Policies and interventions to increase older African Americans' use of preventive health services should consider structural (e.g. health insurance) and psychological (e.g. psychological competency and vulnerability) factors along with the interaction …
Attitudes Toward Anger Management Scale: Development And Initial Validation, David J. Boudreaux, Eric R. Dahlen, Michael B. Madson, Emily Bullock-Yowell
Attitudes Toward Anger Management Scale: Development And Initial Validation, David J. Boudreaux, Eric R. Dahlen, Michael B. Madson, Emily Bullock-Yowell
Faculty Publications
This article describes the development and preliminary validation of the Attitudes Toward Anger Management Scale (ATAMS), a self-report measure of attitudes toward anger management services. Undergraduate volunteers (N = 415) completed an initial version of the instrument. Principal components analysis yielded a two-factor solution. Convergent and incremental validities were supported.
The Year Of Magical Thinking: Fraud, Loss, And Grief, Jayne W. Barnard
The Year Of Magical Thinking: Fraud, Loss, And Grief, Jayne W. Barnard
Faculty Publications
In The Year of Magical Thinking, her wrenching memoir of the year following the death of her husband John Gregory Dunne, Joan Didion describes the episodes of magical thinking that forestalled her acceptance of Dunne's sudden absence from her life. In the hours after his death, she charged his cell phone. Weeks later, she gave his clothes to charity but kept his shoes because, she thought, "He would need shoes if he were to return."
Modern grief theory tells us that episodes like these are common during the months following a loved one's death, particularly when the death, like …
Common Variants Associated With Plasma Triglycerides And Risk For Coronary Artery Disease, Ron Do, Cristen J. Willer, Ellen M. Schmidt, Sebanti Sengupta, Chi Gao, Gina M. Peloso, Stefan Gustafsson, Stavroula Kanoni, Andrea Ganna, Jin Chen, Martin L. Buchkovich, Samia Mora, Jacques S. Beckmann, Jennifer L. Bragg-Gresham, Hsing Yi Chang, Ayse Demirkan, Heleen M. Den Hertog, Louise A. Donnelly, Georg B. Ehret, Tõnu Esko, Mary F. Feitosa, Teresa Ferreira, Krista Fischer, Pierre Fontanillas, Ross M. Fraser, Daniel F. Freitag, Deepti Gurdasani, Kauko Heikkilä, Elina Hyppönen, Aaron Isaacs, Anne U. Jackson, Åsa Johansson, Toby Johnson
Common Variants Associated With Plasma Triglycerides And Risk For Coronary Artery Disease, Ron Do, Cristen J. Willer, Ellen M. Schmidt, Sebanti Sengupta, Chi Gao, Gina M. Peloso, Stefan Gustafsson, Stavroula Kanoni, Andrea Ganna, Jin Chen, Martin L. Buchkovich, Samia Mora, Jacques S. Beckmann, Jennifer L. Bragg-Gresham, Hsing Yi Chang, Ayse Demirkan, Heleen M. Den Hertog, Louise A. Donnelly, Georg B. Ehret, Tõnu Esko, Mary F. Feitosa, Teresa Ferreira, Krista Fischer, Pierre Fontanillas, Ross M. Fraser, Daniel F. Freitag, Deepti Gurdasani, Kauko Heikkilä, Elina Hyppönen, Aaron Isaacs, Anne U. Jackson, Åsa Johansson, Toby Johnson
Faculty Publications
Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery disease (CAD). However, it is unclear whether this association reflects causal processes. We used 185 common variants recently mapped for plasma lipids (P < 5 × 10 -8 for each) to examine the role of triglycerides in risk for CAD. First, we highlight loci associated with both low-density lipoprotein cholesterol (LDL-C) and triglyceride levels, and we show that the direction and magnitude of the associations with both traits are factors in determining CAD risk. Second, we consider loci with only a strong association with triglycerides and show that these loci are also associated with CAD. Finally, in a model accounting for effects on LDL-C and/or high-density lipoprotein cholesterol (HDL-C) levels, the strength of a polymorphism's effect on triglyceride levels is correlated with the magnitude of its effect on CAD risk. These results suggest that triglyceride-rich lipoproteins causally influence risk for CAD. © 2013 Nature America, Inc. All rights reserved.
Graduate Students’ Geropsychology Training Opportunities And Perceived Competence In Working With Older Adults, Erin Woodhead, Erin Emery, Nancy Pachana, Theresa Scott, Candace Konnert, Barry Edelstein
Graduate Students’ Geropsychology Training Opportunities And Perceived Competence In Working With Older Adults, Erin Woodhead, Erin Emery, Nancy Pachana, Theresa Scott, Candace Konnert, Barry Edelstein
Faculty Publications
The current study surveyed clinical and counseling graduate students in the United States (n = 380), Canada (n = 211), Australia (n = 117), and New Zealand (n = 20) to assess geropsychology training opportunities and perceived competency in working with older adults. More geropsychology opportunities were available to participants from the United States and Australia/New Zealand than from Canada. Participants not enrolled in programs with specialty geropsychology tracks reported a lower proportion of faculty doing research, F(1, 537) = 182.13, p < .001 and clinical work, F(1, 452) = 36.13, p < .001 with older adults, lower perceived level of interest among faculty in increasing aging content, F(1, 584) = 59.98, p < .001, fewer aging courses taken, F(1, 582) = 46.91, p < .001, and fewer total practicum hours with older adult clients, F(1, 313) = 10.88, p = .001. For participants enrolled in a program with a specialty track, higher levels of perceived competency were associated with higher levels of perceived interest among faculty in increasing aging content (β = 0.29, p = .045) and more courses that included geropsychology topics (β = 0.42, p = .020). Significant associations were similar for participants not enrolled in a program with a specialty track, except that more practicum sites with older adults (β = 0.19, p = .002) and more total practicum hours with older adults (β = 0.31, p < .001) were also associated with ratings of perceived competency. Participants anticipated working with older adults in their future careers via seeing a wide age range of clients in independent practice, working in a specialty that includes older adults (neuropsychology), or including older family members in services. (PsycINFO Database Record (c) 2013 APA, all rights reserved)
Child Welfare Partnership For Research And Training: A Title Iv-E University/Community Collaborative Research Model, Laurie Drabble, Kathy Lemon, Amy D'Andrade, Brett Donoviel, Julia Le
Child Welfare Partnership For Research And Training: A Title Iv-E University/Community Collaborative Research Model, Laurie Drabble, Kathy Lemon, Amy D'Andrade, Brett Donoviel, Julia Le
Faculty Publications
University-community partnerships are increasingly recognized as valuable in educating students for professional practice and bridging the gap between research and practice. This manuscript describes the evolution and design of a university-community partnership between a School of Social Work in one urban university and local child welfare agencies: the Child Welfare Partnership for Research and Training (CW-PART). This local partnership illustrates types of opportunities and outcomes that emerge when state and local entities leverage greater results from federal funding through partnerships with local universities. The manuscript describes 1), the community-engaged framework used to inform the overall approach and partner roles; 2) …