Digital Commons Network^™

Adipocyte-Derived Cchamide-1, Eiger, Growth-Blocking Peptide 3, And Unpaired 2 Regulate Drosophila Melanogaster Oogenesis, Chad Simmons, Isaiah H. Williams, Tancia W. Bradshaw, Alissa R. Armstrong

Faculty Publications

In addition to energy storage, adipose tissue communication to other organs plays a key role in regulating organismal physiology. While the link between adipose tissue dysfunction and pathophysiology, including diabetes, chronic inflammation, and infertility, is clear, the molecular mechanisms that underlie these associations have not been fully described. We use Drosophila melanogaster as a model to better understand how adipose tissue communicates to the ovary. In this study, we utilized D. melanogaster’s robust genetic toolkit to examine the role of five adipokines known to control larval growth during development, CCHamide-1, CCHamide-2, eiger, Growth-blocking peptide 3, and unpaired 2 in regulating …

A Hybrid Type I Randomized Effectiveness-Implementation Trial Of A Naturalistic Developmental Behavioral Intervention In The Part C Early Intervention System: Study Protocol, Allison L. Wainer, Sarah Edmunds, Alice S. Carter, Wendy L. Stone, R. Christopher Sheldrick, Sarabeth Broder-Fingert, Yael S. Stern, Ellie Harrington, Lisa V. Ibanez, Brooke Ingersoll

Faculty Publications

Background

Participation in Naturalistic Developmental Behavioral Interventions (NDBI) is associated with significant improvements in functioning for toddlers with, and showing early signs of, autism spectrum disorder. The Part C Early Intervention (EI) system, which is publicly funded and available in all U.S. states, offers an optimal infrastructure through which toddlers can receive NDBIs. This study seeks to assess the effectiveness and fit of one NDBI, Caregiver Implemented Reciprocal Imitation Teaching (CI-RIT), within the Part C EI system.

Methods

This hybrid type 1 effectiveness/implementation trial uses a multi-site randomized control design to simultaneously test effectiveness and collect implementation data on CI-RIT …

Fifty Years Of Exponent Ii, Karen Glenn, John Murphy, Bethany Budge

Faculty Publications

Drawing from the Exponent II Records (MSS 1527) in the L. Tom Perry Special Collections, this exhibit featured photographs, writings, and records that document the first fifty years of the periodical Exponent II, a publication dedicated to Latter-day Saint women's voices. Display items included letters, original and draft publications, advertising materials, and scrapbook pages.

The exhibit illustrates that Exponent II has played a significant role in preserving and amplifying the voices of Latter-day Saint women for five decades.

Robotics In Early Childhood Stem Education (Rec-Stemed): The Impact On Preservice Teachers’ Attitudes And Intentions Toward Computational Thinking, Lucus Vasconcelos Ph.D., Ismahan Arslan-Ari, Bridget Miller, Renato Gonzalez-Tapia

Faculty Publications

There is a large disconnect between the increasing need for computer science education in K-12 schools and the preservice teacher training provided. Consequently, preservice teachers may graduate feeling unprepared to infuse computer science concepts such as computational thinking (CT) into their teaching. To address this, we created Robotics in Early Childhood STEM Education (REC-STEMEd), a module that infuses computational thinking, robotics, and science content into an early childhood teacher education methods course. This study investigated changes in early childhood preservice teachers’ (n = 39) attitudes toward learning to teach CT and their intentions to teach CT. Findings revealed a statistically …

Quality Of Life In Caregivers Of Toddlers With Autism Features, Sarah Edmunds, Daina M. Tagavi, Collen M. Harker, Trent Deschamps, Wendy L. Stone

Faculty Publications

Understanding factors that contribute to the quality of life (QoL) of primary caregivers of young autistic children can help researchers and clinicians provide high-quality support to caregivers and families. This study examined whether family demographic factors, parenting stress, and caregivers’ perceptions of family-centered healthcare experiences uniquely predict caregivers’ QoL. Participants were caregivers of toddlers with: features of autism (n = 119), other developmental delays (n = 101), and no developmental concerns (n = 264). We hypothesized that higher levels of perceived family-centered care would moderate (ameliorate) the relation between parenting stress and QoL. Higher levels of perceived family-centered …

Illustrations Of Benevolent And Hostile Heterosexism In Lgbtq+ People’S Lives, Jes L. Matsick, Lindsay Palmer, Flora Oswald, Mary Kruk, Kenneth Ye

Faculty Publications

In this study, we aimed to define heterosexism—a form of sexual stigma that accounts for interpersonal attitudes and institutionalized ideology—in a multi-dimensional way, centering on LGBTQ+ people’s experiences. We draw from an ambivalent theory of prejudice and focus on heterosexism, or an ideology that stigmatizes nonheterosexual behaviors, identities, relationships, and communities. We aimed to learn how LGBTQ+ people would narrate their experiences of heterosexism within a benevolent and hostile framing. In a qualitative online study, LGBTQ+ participants (N = 77; 49% White) reviewed definitions of and recalled encounters with benevolent and hostile heterosexism, providing examples of how heterosexism manifests …

Racial And Ethnic Inequalities In Actual Vs Nearest Delivery Hospitals, Nansi S. Boghossian, Lucy T. Greenberg, Jeffrey S. Buzas, Joshua Radack, Molly Passarella, Jeannette Rogowski, George R. Saade, Ciaran S. Phibbs, Scott A. Lorch

Faculty Publications

IMPORTANCE Minoritized racial and ethnic groups, such as American Indian and Black individuals, often receive lower quality health care compared with White individuals. There is limited understanding of how these disparities extend to obstetric care, particularly when comparing the quality of care at the actual delivery hospital vs the nearest obstetric hospital based on the birthing individual’s residence. OBJECTIVE To examine inequality in care based on the actual delivery hospital and the closest delivery hospital to the birthing individual’s residential zip code centroid. DESIGN, SETTING, AND PARTICIPANTS This population-based retrospective cohort study used data from 5 states (2008 to 2020 …

Family Risk Classes Predict Longitudinal Parent And Child Outcomes: Understanding The Implications Of Poverty-Related Adversity, Daniel K. Cooper, Benjamin L. Bayly, Brianna Tennie, Francesca Lupini, Martha E. Wadsworth

Faculty Publications

Experiencing poverty and associated risk factors can be detrimental to families’ mental health and well-being. However, it is unclear whether experiencing specific types or patterns of adversity leads to distinct outcomes. Guided by the Family Stress Model, the objective of this study was to (a) identify unique family risk classes based on exposure to various combinations of poverty-related adversity and (b) examine whether the family risk classes differed in their levels of parental coping strategies, couple relationship quality, parenting practices, and child behavior problems. The sample included 301 mother–father–child triads (602 adults and 301 children) with a combined income ≤ …

New Method Of Impact Localization On Plate-Like Structures Using Deep Learning And Wavelet Transform, Asaad Migot, Ahmed Saaudi, Victor Giurgiutiu

Faculty Publications

This paper presents a new methodology for localizing impact events on plate-like structures using a proposed two-dimensional convolutional neural network (CNN) and received impact signals. A network of four piezoelectric wafer active sensors (PWAS) was installed on the tested plate to acquire impact signals. These signals consisted of reflection waves that provided valuable information about impact events. In this methodology, each of the received signals was divided into several equal segments. Then, a wavelet transform (WT)-based time-frequency analysis was used for processing each segment signal. The generated WT diagrams of these segments’ signals were cropped and resized using MATLAB code …

Special Delivery Of Proteinaceous Matter To Deep-Sea Microbes, Yuan Shen, Ronald Benner, Taylor A.B. Broek, Brett D. Walker, Matthew D. Mccarthy

Faculty Publications

Earth’s deep ocean holds a vast reservoir of dissolved organic carbon, traditionally considered old and resistant to microbial degradation. Radiocarbon analyses indicate the hidden occurrence of younger dissolved organic carbon components, assumed to be accessible to deep-sea microorganisms but not yet demonstrated. Using compound-class radiocarbon analysis, molecular characterization, and bioassay experiments, we provide direct evidence for rapid microbial utilization of young, labile, high–molecular weight proteinaceous material in bathypelagic waters. The abundance of labile proteinaceous material diminishes from epipelagic to mesopelagic waters but notably increases in bathypelagic waters, where it exhibits a short turnover time (days) and resembles surface plankton in …

Neurosymbolic Knowledge-Grounded Planning And Reasoning In Ai Systems, Amit Sheth, Vedant Khandelwal, Kaushik Roy, Vishal Pallagani, Megha Chakraborty

Faculty Publications

To build AI systems capable of decision-support assistance, such as AI-assisted healthcare, it is essential to develop user-centric decision-making processes that are robust, interpretable, and capable of effectively processing and acting on natural language interactions. Instruction-based prompting of large language models has demonstrated considerable success in supporting humans with information assistance tasks, including creative writing and content generation. However, recent studies reveal that language models exhibit limitations in performing complex reasoning and planning tasks, such as constructing compositional or hierarchical plans involving multiple reasoning steps. To address these challenges, we propose a neurosymbolic framework that integrates large language models with …

Mirrors For Pacific Islander Children: Teaching Resilience Through Culturally Adapted Bibliotherapy, Isabel Medina Hull, Elizabeth Cutrer, Paul H. Ricks, G. E. Kawika Allen, Kendra M. Hall-Kenyon, Lorena Seu, Kristopher J. Urbina, Melia Fonoimoana Garrett

Faculty Publications

Pacific Islander youth face disproportionately high rates of suicide and mental health challenges, yet culturally appropriate interventions remain scarce. This study investigated whether culturally adapted bibliotherapy could effectively promote resilience in American Samoan children by incorporating culturally relevant stories and coping strategies. Through collaboration with on-island Samoan cultural brokers, we developed and implemented culturally adapted stories and lessons designed to resonate with the experiences of children in American Samoa. The study employed a mixed-methods approach with 34 American Samoan children aged 5–13 years, using observations, adapted card sorts, and forced-choice procedures to measure responses to the intervention. The results demonstrated …

Msbzip55 Regulates Salinity Tolerance By Modulating Melatonin Biosynthesis In Alfalfa, Tingting Wang, Jiaqi Yang, Jiamin Cao, Qi Zhang, Huayue Liu, Peng Li, Yizhi Huang, Wenwu Qian, Xiaojing Bi, Hui Wang, Yunwei Zhang

Faculty Publications

No abstract provided.

Alcohol Use Disorder Medication Coverage And Utilization Management In Medicaid Managed Care Plans, Maureen T. Stewart, Sage R. Feltus, Christina Andrews Ph.D., Andrea Acevedo, Cindy Parks Thomas, Jeffrey Bratberg, Constance M. Horgan, Dominic Hodgkin, Rachel Sayko Adams

Faculty Publications

IMPORTANCE Evidence-based, patient-centered treatment for alcohol use disorder (AUD) can include pharmacotherapy with naltrexone, acamprosate, or disulfiram; however, these medications are rarely used. Medicaid managed care plans (MCPs) manage health services for nearly 80% of Medicaid enrollees and are the largest payer for addiction treatment services. Little is known about Medicaid MCP policies for AUD medications.

OBJECTIVES To describe Medicaid MCPs’ coverage and management of acamprosate, naltrexone, and disulfiram for AUD and examine associations of plan characteristics and state policies with medication coverage.

DESIGN, SETTING, AND PARTICIPANTS In this cross-sectional study, a content analysis was performed of 2021 insurance benefit …

Real-Time Defect Detection And Classification In Robotic Assembly Lines: A Machine Learning Framework, Fadi El Kalach, Mojtaba Farahani, Thorsten Wuest, Ramy Harik

Faculty Publications

Manufacturing systems have witnessed a significant transformation with the introduction of Industry 4.0, introducing new capabilities with the emergence of new technologies. One such instance is the proliferation of sensors enabling the generation and acquisition of vast amounts of data, leading to advancements in Artificial Intelligence (AI) for manufacturing. One field profiting from this is that of Time Series Analytics (TSC) which includes forecasting and classification. TSC can be crucial for fault detection and diagnosis in manufacturing systems. However, there are still challenges in utilizing manufacturing datasets to train and deploy classification algorithms for real time classification. As such this …

Synthesis Of A Series Of Rare-Earth-Based Multi-Anion Chalcogenide Iodides Re3Si2SeXS8-XI (Re = La, Ce, Pr, And Nd) Using The Flux-Assisted Boron-Chalcogen Mixture Method, Gopabandhu Panigrahi, Habiba Binte Kashem, Gregory Morrison, Hans Conrad Zur Loye

Faculty Publications

Single crystals and polycrystalline powders of rare earth mixed chalcogenide iodides La3Si2Se1.21S6.79I, Ce3Si2Se1.39S6.61I, Pr3Si2Se1.22S6.78I, and Nd3Si2Se1.18S6.82I were prepared using the reactive flux-assisted boron-chalcogen mixture (BCM) method at 850 °C. All compounds crystallized in the monoclinic crystal system, space group C2/c (space group number 15). The series adopts the La3Si2O8Cl structure type, containing isolated SiQ4 tetrahedra connected by REQ8 (RE = La, Ce, Pr and Nd) polyhedra; this arrangement creates tunnels that are filled by I atoms. The partial substitution of S by Se was carried out to modulate the optical properties. Phase pure samples and uniform solid solutions were obtained …

Toward A Unified Conceptualization Of Social Capital, Paulina Erices-Ocampo, Miranda J. Lubbers, Jimi Adams

Faculty Publications

Social capital is among the most broadly used concepts in social science. Despite its shared understanding as beneficial resources available from the connections between people, authors vary widely in their conceptualizations of social capital. To extract clarity from these disparate perspectives, we offer a systematic framework for conceptualizing social capital, which identifies three primary theoretical dimensions of scholars’ conceptualizations of social capital: (a) where beneficial resources reside, ranging from within individuals to the relationships between individuals; (b) beneficial network structure, differentiating closure from brokerage arrangements; and (c) the level to which rewards accrue, distinguishing individual from collective benefits. We illustrate …

Time-Series Forecasting In Smart Manufacturing Systems: An Experimental Evaluation Of The State-Of-The-Art Algorithms, Mojaba A. Farahani, Fadi El Kalach, Austin Harper, M.R. Mccormick, Ramy Harik, Thorsten Wuest

Faculty Publications

Time-Series Forecasting (TSF) is a growing research area across various domains including manufacturing. Manufacturing can benefit from Artificial Intelligence (AI) and Machine Learning (ML) innovations for TSF tasks. Although numerous TSF algorithms have been developed and proposed over the past decades, the critical validation and experimental evaluation of the algorithms hold substantial value for researchers and practitioners and are missing to date. This study aims to fill this research gap by providing a rigorous experimental evaluation of the state-of-the-art TSF algorithms on thirteen manufacturing-related datasets with a focus on their applicability in smart manufacturing environments. Each algorithm was selected based …

Does Travel Time Matter?: Predictors Of Transportation Vulnerability And Access To Hiv Care Among People Living With Hiv In South Carolina, Sayward Elizabeth Harrison, Peiyin Hung, Katherine Green, Sarah J. Miller, Mariajosé Patron, Divya Ahuja, Sharon Weissman, Caroline Rudisill, Tammeka Evans

Faculty Publications

Background

People living with HIV (PLHIV) in the southern United States (US) are at high risk for poor outcomes across the HIV care continuum leading to low rates of viral suppression. Understanding structural barriers to care—including transportation vulnerability—is critical to improve HIV outcomes. This study investigated relationships between travel time to HIV care, transportation vulnerability, and HIV care disruptions to inform future transportation interventions for PLHIV residing in South Carolina and other southern US states.

Methods

A total of 160 PLHIV (N = 160) were recruited from a large immunology center in South Carolina. Participants reported on transportation experiences, transportation …

Comparison Of Deep Learning And Traditional Machine Learning Models For Predicting Mild Cognitive Impairment Using Plasma Proteomic Biomarkers, Kesheng Wang Phd, Ma, Bs, Donald A. Adjeroh, Wei Fang, Suzy M. Walter, Danqing Xiao, Ubolrat Piamjariyakul, Chun Xu

Faculty Publications

Mild cognitive impairment (MCI) is a clinical condition characterized by a decline in cognitive ability and progression of cognitive impairment. It is often considered a transitional stage between normal aging and Alzheimer’s disease (AD). This study aimed to compare deep learning (DL) and traditional machine learning (ML) methods in predicting MCI using plasma proteomic biomarkers. A total of 239 adults were selected from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort along with a pool of 146 plasma proteomic biomarkers. We evaluated seven traditional ML models (support vector machines (SVMs), logistic regression (LR), naïve Bayes (NB), random forest (RF), k-nearest neighbor …

Enhancing Mucus Flow And Clearance By Grafting Zwitterionic Hydrogel Films To Luminal Surfaces, Ryan Horne, Caleb Escudero, Morgan Ellerman, C. Allan Guymon, Marlan Hansen

Faculty Publications

Objective

To determine the effects of zwitterionic hydrogel films on mucus contact angles, flow, and stasis with respect to medical polymer surfaces, both flat and tubular.

Methods

A zwitterionic hydrogel thin film was photografted onto medical rubber surfaces and compared against non-zwitterionic hydrogel thin films and untreated surfaces to determine its impact on mucus contact angles, mucus flow on sheets and tubes, and mucus plugging.

Results

Zwitterionic and conventional hydrogel films significantly reduce the mucus contact angles and the tilt required to initiate mucus flow on sheets and in tubular systems. Preliminary experiments show that these films may also shorten …

Time-Dependent Shear Flows And Their Applications In Parabolic–Parabolic Patlak–Keller–Segel Systems*, Siming He

Faculty Publications

In this study, we investigate the behavior of three-dimensional parabolic–parabolic Patlak–Keller–Segel systems in the presence of ambient shear flows. Our findings demonstrate that when the total mass of the cell density is below a specific threshold, the solution remains globally regular as long as the flow is sufficiently strong. The primary difficulty in our analysis stems from the fast creation of chemical gradients due to strong shear advection.

Friction-Based Recycling: An Evaluation Of Friction Extrusion For Fabricating Ti-6al-4 V Wire Fabricated From Machining Chip Feedstock, Devesh Kumar Chouhan, Mageshwari Komarasamy, Scott B. Taysom, Nicole R. Overman, Nathan L. Canfield, Timothy J. Roosendaal, Anthony P. Reynolds, Scott A. Whalen

Faculty Publications

Titanium and its alloys are used in aviation and automobile industries due to their remarkable strength to weight ratio, but machining loss commonly is high with ~ 80 wt% of the material being converted to scrap. Recycling post-consumer Ti scrap directly into solid bulk products is a potential solution for repurposing valuable material. Further, eliminating fresh Ti sponge during recycling might lead to lower energy and greenhouse gas emissions. In this study, a solid-phase process known as friction extrusion was utilized to recycle Ti-6Al-4 V machining chips into solid wires which could be used as feedstock in additive manufacturing. The …

Nucleoredoxin Regulates Wnt Signaling During Pituitary Stem Cell Differentiation, Michelle L. Brinkmeier, Leonard Y M Cheung, Sean P. O'Connell, Diana K. Gutierrez, Eve C. Rhoads, Sally A. Camper, Shannon W. Davis

Faculty Publications

Nucleoredoxin (Nxn) encodes a multi-functional enzyme with oxidoreductase activity that regulates many different signaling pathways and cellular processes in a redox-dependent manner. Rare NXN mutations are reported in individuals with recessive Robinow syndrome, which involves mesomelic skeletal dysplasia, short stature, craniofacial dysmorphisms, and incompletely penetrant heart and palate defects. Here we report that Nxn is expressed in the ventral diencephalon and developing pituitary gland, and that Nxn deficient mice have pituitary dysmorphology and craniofacial abnormalities that include defects in the skull base and cleft palate. Nxn mutant mice exhibit reduced WNT signaling and reduced differentiation of pituitary stem …

Pre-Exposure Prophylaxis Uptake Among Black/African American Men Who Have Sex With Other Men In Midwestern, United States: A Systematic Review, Oluwafemi Adeagbo, Oluwaseun Abdulganiyu Badru, Prince Addo, Amber Hawkins, Monique J. Brown Ph.D., Mph, Xiaoming Li, Rima Afifi

Faculty Publications

Introduction: Black/African American men who have sex with other men (BMSM) are disproportionately affected by HIV, experience significant disparities in HIV incidence, and face significant barriers to accessing HIV treatment and care services, including pre-exposure prophylaxis (PrEP). Despite evidence of individual and structural barriers to PrEP use in the Midwest, no review has synthesized this finding to have a holistic view of PrEP uptake and barriers. This review examines patterns of, barriers to, and facilitators of PrEP uptake among BMSM in the Midwest, United States (US).

Methods: Five databases (CINAHL Plus, PUBMED, PsycINFO, SCOPUS, and Web of Science) were searched …

Byu Nano-Carbon Physics Lab, Robert Davis Dr., Richard Vanfleet Dr., Felipe Rivera Dr., David Hayes, Nick Allen, Bridget Kemper, Dan Broadbent

Faculty Publications

BYU Nano-Carbon Physics Lab

Started in 2003 by Physics Professors Robert Davis and Richard Vanfleet, who received the BYU Technology Transfer Award in 2024.

Over 81 undergraduate and 21 graduate student projects in the lab have advanced carbon nanotube (CNT) research.

Applications of research from the lab have resulted in over 30 patents, many of which have been licensed to companies for use in the world.

This display showcases highlights of work done in the lab.

Uncertainty Propagation And Sensitivity Analysis For Constrained Optimization Of Nuclear Waste Vitrification, Lagrande Gunnell, Xiaonan Lu, John D. Vienna, Dong-Sang Kim, Brian J. Riley, John Hedengren

Faculty Publications

The vitrification of high-level waste (HLW) by heating a mixture of glass-forming chemicals (GFCs) with the waste can be improved using a constrained optimization problem. This study explores how different uncertainty propagation (UP) methods implemented with the optimization process can affect the glass formulation of nuclear waste glasses. UP is the effort of propagating uncertain inputs through a system to understand and quantify output distributions. Uncertainty intervals are crafted from output distributions to inform the optimization algorithm. UP is often implemented with Monte Carlo (MC) sampling for large nonlinear systems, which can be difficult to implement within a constrained optimization …

Disruption Of G3bp1 Granules Promotes Mammalian Cns And Pns Axon Regeneration, Pabitra K. Sahoo, Manasi Agrawal, Nicholas Hanovice, Patricia J. Ward, Meghal Desai, Terika P. Smith, Hao Min Sima, Jennifer N. Dulin, Lauren S. Vaughn, Mark H. Tuszynski, Kristy Welshhans, Larry I. Benowitz, Arthur W. English, John D. Houle, Jeffery L. Twiss

Faculty Publications

Depletion or inhibition of core stress granule proteins, G3BP1 in mammals and TIAR-2 in Caenorhabditis elegans, increases the growth of spontaneously regenerating axons. Inhibition of G3BP1 by expression of its acidic or “B-domain” accelerates axon regeneration after nerve injury, bringing a potential therapeutic strategy for peripheral nerve repair. Here, we asked whether G3BP1 inhibition is a viable strategy to promote regeneration in injured mammalian central nervous system (CNS) where axons do not regenerate spontaneously. G3BP1 B-domain expression was found to promote axon regeneration in the transected spinal cord provided with a permissive peripheral nerve graft (PNG) as well as in …

Disruption Of G3bp1 Granules Promotes Mammalian Cns And Pns Axon Regeneration, Pabitra K. Sahoo, Manasi Agrawal, Nicholas Hanovice, Patricia J. Ward, Meghal Desai, Terika P. Smith, Haomin Sima, Jennifer N. Dulin, Lauren S. Vaughn, Mark H. Tuszynski, Kristy Welshhans, Larry I. Benowitz, Arthur W. English, John D. Houle, Jeffery L. Twiss

Faculty Publications

Depletion or inhibition of core stress granule proteins, G3BP1 in mammals and TIAR-2 in Caenorhabditis elegans, increases the growth of spontaneously regenerating axons. Inhibition of G3BP1 by expression of its acidic or “B-domain” accelerates axon regeneration after nerve injury, bringing a potential therapeutic strategy for peripheral nerve repair. Here, we asked whether G3BP1 inhibition is a viable strategy to promote regeneration in injured mammalian central nervous system (CNS) where axons do not regenerate spontaneously. G3BP1 B-domain expression was found to promote axon regeneration in the transected spinal cord provided with a permissive peripheral nerve graft (PNG) as well as …

Understanding Ionic Transport In Perovskite Lithium-Ion Conductor Li3/8Sr7/16Ta3/4Hf1/4O3: A Neutron Diffraction And Molecular Dynamics Simulation Study †, Danyi Sun, Nan Wu, Yeting Wen, Shichen Sun, Yufang He, Ke Huang, Cheng Li, Bin Ouyang, Ralph E. White, Kevin Huang

Faculty Publications

Solid-state Li-ion electrolytes (SSEs) are essential for the development of next-generation solid-state Li-metal batteries and new Li-extraction electrochemical cells. Among these, the perovskite-type SSE Li3/8Sr7/16Ta3/4Hf1/4O3 (LSTH) has garnered attention for Li-extraction applications, owing to its outstanding chemical and thermal stability and high ionic conductivity. However, its precise crystal structure and Li-ion transport mechanisms remain insufficiently understood. This study addresses these gaps by employing neutron diffraction to resolve LSTH's crystallography and machine learning force field (MLFF) based MD simulations to elucidate ionic transport mechanisms. A single-phase LSTH, synthesized via the sol–gel method, exhibits a room-temperature bulk conductivity of 0.418 mS cm−1 …