Digital Commons Network^™

Independent Contributions Of Structural And Functional Connectivity: Evidence From A Stroke Model, Lynsey M. Keator, Grigori Yourganov, Alexandra Basilakos, Argye E. Hillis, Gregory Hickok, Leonardo Bonilha, Chris Rorden, Julius Fridriksson

Faculty Publications

Altered functional connectivity is related to severity of language impairment in poststroke aphasia. However, it is not clear whether this finding specifically reflects loss of functional coherence, or more generally, is related to decreased structural connectivity due to cortical necrosis. The aim of the current study was to investigate this issue by factoring out structural connectivity from functional connectivity measures and then relating the residual data to language performance poststroke. Ninety-seven participants with a history of stroke were assessed using language impairment measures (Auditory Verbal Comprehension and Spontaneous Speech scores from the Western Aphasia Battery-Revised) and MRI (structural, diffusion tensor …

Adaptation Of The Agency For Healthcare Research And Quality’S ‘Hospital Survey On Patient Safety Culture’ To The Bosnia And Herzegovina Context, Šehad Draganović, Guido Offermanns, Rachel E. Davis

Faculty Publications

OBJECTIVES: Measuring staff perspectives on patient safety culture (PSC) can identify areas of concern that, if addressed, could lead to improvements in healthcare. To date, there is no validated measure to assess PSC that has been tested and adapted for use in Bosnia and Herzegovina (BiH). This research addresses the gap in the evidence through the psychometric assessment of the Agency for Healthcare Research and Quality's: 'Hospital Survey on Patient Safety Culture' (HSOPSC), to determine its suitability for the health system in BiH. SETTING: Nine hospitals. PARTICIPANTS: Healthcare professionals (n=1429); nurse (n=823), doctors (n=328), other clinical personnel (n=111), non-clinical personnel …

Racism As Public Health Crisis: Assessment And Review Of Municipal Declarations And Resolutions Across The United States, Dara D. Mendez, Jewel Scott Phd, Rn, Fnp-C, Linda Adodoadji, Christina Toval, Monica Mcneil, Mahima Sindhu

Faculty Publications

Racism in the United States has been cited as a key driver of racial health inequities. Racism as a public health crisis has been in the forefront, particularly with respect to state and municipal governments that have developed legislation, resolutions, and declarations. This policy brief includes a review of resolutions and declarations across the US related to Racism as a Public Health Crisis through the end of September 2020. There were 125 resolutions reviewed for content related to the history of racism, reference to racial health equity data, content related to action steps or implementation, and any accompanying funding or …

Racism As Public Health Crisis: Assessment And Review Of Municipal Declarations And Resolutions Across The United States, Dara D. Mendez, Jewel Scott Phd, Rn, Fnp-C, Linda Adodoadji, Christina Toval, Monica Mcneil, Mahima Sindhu

Faculty Publications

Racism in the United States has been cited as a key driver of racial health inequities. Racism as a public health crisis has been in the forefront, particularly with respect to state and municipal governments that have developed legislation, resolutions, and declarations. This policy brief includes a review of resolutions and declarations across the US related to Racism as a Public Health Crisis through the end of September 2020. There were 125 resolutions reviewed for content related to the history of racism, reference to racial health equity data, content related to action steps or implementation, and any accompanying funding or …

Normalization Of Muscle Strength Measurements In The Assessment Of Cardiometabolic Risk Factors In Adolescents, Tiago Rodrigues De Lima, Xuemei Sui M.D., M.P.H., Ph.D., Diego Augusto Santos Silva

Faculty Publications

Muscle strength (MS) has been associated with cardiometabolic risk factors (CMR) in adolescents, however, the impact attributed to body size in determining muscle strength or whether body size acts as a confounder in this relationship remains controversial. We investigated the association between absolute MS and MS normalized for body size with CMR in adolescents. This was a cross-sectional study comprising 351 adolescents (44.4% male; 16.6 ± 1.0 years) from Brazil. MS was assessed by handgrip and normalized for body weight, body mass index (BMI), height, and fat mass. CMR included obesity, high blood pressure, dyslipidemia, glucose imbalance, and high inflammation …

Covid-19 Protocols In Academic Libraries In Canada And The United States: An Acrl Val Report, Holt Zaugg, Jeffrey Bullington, Stephanie Farne, Beate Gersch, Jo Ann Murphy, Lamonica Sanford

Faculty Publications

In the Fall of 2020, as the COVID-19 pandemic raged throughout the world, educational institutions pivoted to online learning and supporting services, especially those found in academic libraries, adjusted. To better understand measures taken by academic libraries in Canada and the United States, the Association of College & Research Libraries’ (ACRL) Value of Academic Libraries (VAL) committee formed a subcommittee to examine how academic libraries adjusted and provided services to their respective institutions during COVID-19 pandemic. This report is the culmination of this examination.

Water Insecurity Is Associated With Lack Of Viral Suppression And Greater Odds Of Aids-Defining Illnesses Among Adults With Hiv In Western Kenya, Jason M. Nagata, Joshua D. Miller, Craig R. Cohen, Edward A. Frongillo Jr., Elly Weke, Rachel Burger, Pauline Wekesa, Lila A. Sheira, A Rain Mocello, Phelgona Otieno, Lisa M. Butler, Elizabeth A. Bukusi, Sheri D. Weiser, Sera L. Young

Faculty Publications

Reliable access to safe and acceptable water in sufficient quantities (i.e., water security) is important for medication adherence and limiting pathogen exposure, yet prior studies have only considered the role of food security as a social determinant of HIV-related health. Therefore, the objective of this analysis was to assess the relationships between household water insecurity and HIV-related outcomes among adults living with HIV in western Kenya (N = 716). We conducted a cross-sectional analysis of baseline data from Shamba Maisha (NCT02815579), a cluster randomized controlled trial of a multisectoral agricultural and asset loan intervention. Baseline data were collected from June …

Local Translation Across Neural Development: A Focus On Radial Glial Cells, Axons, And Synaptogenesis, Manasu Agrawal, Kristy Welshhans

Faculty Publications

In the past two decades, significant progress has been made in our understanding of mRNA localization and translation at distal sites in axons and dendrites. The existing literature shows that local translation is regulated in a temporally and spatially restricted manner and is critical throughout embryonic and post-embryonic life. Here, recent key findings about mRNA localization and local translation across the various stages of neural development, including neurogenesis, axon development, and synaptogenesis, are reviewed. In the early stages of development, mRNAs are localized and locally translated in the endfeet of radial glial cells, but much is still unexplored about their …

Measuring Routine Childhood Vaccination Coverage In 204 Countries And Territories, 1980–2019: A Systematic Analysis For The Global Burden Of Disease Study 2020, Release 1, Natalie C. Galles, Patrick Y. Liu, Rachel L. Updike, Nancy Fullman, Jason Nguyen, Sam Rolfe, Ismaeel Yunusa, Et Al.

Faculty Publications

Background

Methods

Covid-19 Disrupted Provision And Utilization Of Health And Nutrition Services In Uttar Pradesh, India: Insights From Service Providers, Household Phone Surveys, And Administrative Data, Phuong H. Nguyen, Shivani Kachwaha, Anjali Pant, Lan M. Tran, Monika Walia, Sebanti Ghosh, Praveen K. Sharma, Jessica Escobar-Alegria, Edward A. Frongillo Jr., Purnima Menon, Rasmi Avula

Faculty Publications

BACKGROUND: The coronavirus (COVID-19) pandemic may substantially affect health systems, but little primary evidence is available on disruption of health and nutrition services. OBJECTIVES: This study aimed to 1) determine the extent of disruption in provision and utilization of health and nutrition services induced by the pandemic in Uttar Pradesh, India; and 2) identify how adaptations were made to restore service provision in response to the pandemic. METHODS: We conducted longitudinal surveys with frontline workers (FLWs, n = 313) and mothers of children < 2 y old (n = 659) in December 2019 (in-person) and July 2020 (by phone). We also interviewed block-level managers and obtained administrative data. We examined changes in service provision and utilization using Wilcoxon matched-pairs signed-rank tests. RESULTS: Compared with prepandemic, service provision reduced substantially during lockdown (83-98 percentage points, pp), except for home visits and take-home rations (∼ 30%). Most FLWs (68%-90%) restored service provision in July 2020, except for immunization and hot cooked meals (< 10%). Administrative data showed similar patterns of disruption and restoration. FLW fears, increased workload, inadequate personal protective equipment (PPE), and manpower shortages challenged service provision. Key adaptations made to provide services were delivering services to beneficiary homes (∼ 40%-90%), social distancing (80%), and using PPE (40%-50%) and telephones for communication (∼ 20%). On the demand side, service utilization reduced substantially (40-80 pp) during the lockdown, but about half of mothers received home visits and food supplementation. Utilization for most services did not improve after the lockdown, bearing the challenges of limited travel (30%), nonavailability of services (26%), and fear of catching the virus when leaving the house (22%) or meeting service providers (14%). CONCLUSIONS: COVID-19 disrupted the provision and use of health and nutrition services in Uttar Pradesh, India, despite adaptations to restore services. Strengthening logistical support, capacity enhancement, performance management, and demand creation are needed to improve service provision and utilization during and post-COVID-19.

An Assessment Of Government Capacity Building To Restrict The Marketing Of Unhealthy Food And Non-Alcoholic Beverage Products To Children In The Region Of The Americas, Sofía Rincón-Gallardo Patiño, Fabio Da Silva Gomes, Steven Constantinou, Robin Lemaire, Valisa E. Hedrick, Elena L. Serrano, Vivica I. Kraak

Faculty Publications

No abstract provided.

Ca Special Issue On Neural Network Approximation, Wolfgang Dahmen, Ronald A. Devore, Philipp Grohs

Faculty Publications

No abstract provided.

Comparative Efficacy, Safety, Tolerability, And Effectiveness Of Antipsychotics In The Treatment Of Dementia-Related Psychosis (Drp): A Systematic Literature Review, Ismaeel Yunusa, N. Rashid, V. Abler, Krithika Rajagopalan

Faculty Publications

Objectives

To evaluate the comparative efficacy, safety, tolerability, and effectiveness of atypical antipsychotics (AAPs) for the treatment of dementia related psychosis (DRP) in older adults.

Methods

In this systematic literature review (SLR), we qualitatively synthesized evidence on the comparative efficacy (based on neuropsychiatric inventory), tolerability (weight gain), and safety (cerebrovascular adverse events [CVAE], cardiovascular events, mortality, somnolence, extrapyramidal symptoms [EPS]) of AAPs used to treat DRP. We also assessed effectiveness based on all-cause discontinuations and discontinuations due to lack of efficacy or adverse events (AE). Published articles from through March 2021 from PubMed, EMBASE, PsycINFO, and Cochrane databases evaluated. We …

Rapid Computation Of Effective Conductivity Of 2d Composites By Equivalent Circuit And Spectral Methods., Ben J. Ransom, Dean R. Wheeler

Faculty Publications

This work presents models for homogenizing or finding the effective transport or mechanical properties of microscale composites formed from highly contrasting phases described on a grid. The methods developed here are intended for engineering applications where speed and geometrical flexibility are a premium. A canonical case that is mathematically challenging and yet can be applied to many realistic materials is a 4-phase 2-dimensional periodic checkerboard or tiling. While analytic solutions for calculating effective properties exist for some cases, versatile methods are needed to handle anisotropic and non-square grids. A reinterpretation and extension of an existing analytic solution that utilizes equivalent …

The Brass Plates In Context: A Book Of Mormon Backstory, Noel B. Reynolds

Faculty Publications

This paper brings contemporary ANE scholarship in several fields together with the ancient scriptures restored through Joseph Smith to construct an updated starting point for interpretation of the teachings of the Book of Mormon. It assembles findings from studies of ancient scribal culture, historical linguistics and epigraphy, and the history and archaeology of Mesopotamia, Egypt, and the Levant, together with the traditions of ancient Israel and the ancient scriptures restored to Joseph Smith, to construct a contextualized perspective for understanding Lehi, Nephi, and the Brass Plates as they would have been understood by their contemporaries—as prominent bearers of the Josephite …

High-Throughput Discovery Of Novel Cubic Crystal Materials Using Deep Generative Neural Networks, Yong Zhao, Mohammed Al-Fahdi, Ming Hu, Edirisuriya M.D. Siriwardane, Yuqi Song, Alireza Nasiri, Jianjun Hu

Faculty Publications

High-throughput screening has become one of the major strategies for the discovery of novel functional materials. However, its effectiveness is severely limited by the lack of sufficient and diverse materials in current materials repositories such as the open quantum materials database (OQMD). Recent progress in deep learning have enabled generative strategies that learn implicit chemical rules for creating hypothetical materials with new compositions and structures. However, current materials generative models have difficulty in generating structurally diverse, chemically valid, and stable materials. Here we propose CubicGAN, a generative adversarial network (GAN) based deep neural network model for large scale generative design …

Odt Flow: Extracting, Analyzing, And Sharing Multi-Source Multi-Scale Human Mobility, Zhenlong Li, Xiao Huang, Tao Hu, Huan Ning, Xinyue Ye, Binghu Huang, Xiaoming Li

Faculty Publications

In response to the soaring needs of human mobility data, especially during disaster events such as the COVID-19 pandemic, and the associated big data challenges, we develop a scalable online platform for extracting, analyzing, and sharing multi-source multi-scale human mobility flows. Within the platform, an origin-destination-time (ODT) data model is proposed to work with scalable query engines to handle heterogenous mobility data in large volumes with extensive spatial coverage, which allows for efficient extraction, query, and aggregation of billion-level origin-destination (OD) flows in parallel at the server-side. An interactive spatial web portal, ODT Flow Explorer, is developed to allow users …

Individualized Response To Semantic Versus Phonological Aphasia Therapies In Stroke, Sigfus Kristinsson, Alexandra Basilakos, Jordan Elm, Leigh Ann Spell, Leonardo Bonilha, Chris Rorden, Dirk Den Ouden Ph.D., Christy Cassarly, Souvik Sen, Argye Hillis, Gregory Hickok, Julius Fridriksson Ph.D.

Faculty Publications

Attempts to personalize aphasia treatment to the extent where it is possible to reliably predict individual response to a particular treatment have yielded inconclusive results. The current study aimed to (i) compare the effects of phonologically versus semantically focussed naming treatment and (ii) examine biographical and neuropsychological baseline factors predictive of response to each treatment. One hundred and four individuals with chronic post-stroke aphasia underwent 3 weeks of phonologically focussed treatment and 3 weeks of semantically focussed treatment in an unblinded cross-over design. A linear mixed-effects model was used to compare the effects of treatment type on proportional change in …

Spatial Disparities Of Covid-19 Cases And Fatalities In United States Counties, Sarah L. Jackson, Sahar Derakhshan, Leah Blackwood, Logan Lee, Qian Huang, Margot Habets, Susan L. Cutter

Faculty Publications

This paper examines the spatial and temporal trends in county-level COVID-19 cases and fatalities in the United States during the first year of the pandemic (January 2020–January 2021). Statistical and geospatial analyses highlight greater impacts in the Great Plains, Southwestern and Southern regions based on cases and fatalities per 100,000 population. Significant case and fatality spatial clusters were most prevalent between November 2020 and January 2021. Distinct urban–rural differences in COVID-19 experiences uncovered higher rural cases and fatalities per 100,000 population and fewer government mitigation actions enacted in rural counties. High levels of social vulnerability and the absence of mitigation …

Associations Between Fasting Duration, Timing Of First And Last Meal, And Cardiometabolic Endpoints In The National Health And Nutrition Examination Survey, Michael David Wirth, Longgang Zhao, Gabrielle Turner-Mcgrievy, Andrew Ortaglia

Faculty Publications

Background: Research indicates potential cardiometabolic benefits of energy consumption earlier in the day. This study examined the association between fasting duration, timing of first and last meals, and cardiometabolic endpoints using data from the National Health and Nutrition Examination Survey (NHANES). Methods: Cross-sectional data from NHANES (2005–2016) were utilized. Diet was obtained from one to two 24-h dietary recalls to characterize nighttime fasting duration and timing of first and last meal. Blood samples were obtained for characterization of C-reactive protein (CRP); glycosylated hemoglobin (HbA1c %); insulin; glucose; and high-density lipoprotein (HDL), low-density lipoprotein (LDL), and total cholesterol. Survey design procedures …

12 C(E,E'Pn) Measurements Of Short Range Correlations In The Tensor-To-Scalar Interaction Transition Region, I. Korover, J. R. Pybus, A. Schmidt, F. Hauenstein, M. Duer, O. Hen, E. Piasetzky, L. B. Weinstein, D. W. Higinbotham, S. Adhikari, K. Adhikari, M. J. Amaryan, Giovanni Angelini, H. Atac, L. Barion, M. Battaglieri, A. Beck, I. Bedlinkskiy, Fatiha Benmokhtar, Steffen Strauch, Ralf W. Gothe, Krishna Chandra Neupane, Et. Al.

Faculty Publications

High-momentum configurations of nucleon pairs at short-distance are probed using measurements of the C-12(e, e' p) and C-12(e, e' pN) reactions (where N is either n or p), at high-Q(2) and x(B) > 1.1. The data span a missing-momentum range of 300-1000 MeV/c and are predominantly sensitive to the transition region of the strong nuclear interaction from a Tensor to Scalar interaction. The data are well reproduced by theoretical calculations using the Generalized Contact Formalism with both chiral and phenomenological nucleon-nucleon (NN) interaction models. This agreement suggests that the measured high missing-momentum protons up to 1000 MeV/c predominantly belong to short-ranged …

Executive Functioning, Caregiver Monitoring, And Medication Adherence Over Time In Adolescents With Chronic Kidney Disease, Cyd K. Eaton, Kara Mcrae Duraccio, Michelle N. Eakin, Tammy M. Brady, Cozumel S. Pruette, Thomas Eckmann, Susan R. Mendley, Shamir Tuchman, Barbara A. Fivush, Kristen A. Riekert

Faculty Publications

Objective: To evaluate associations between executive functioning and caregiver adherence monitoring with objective antihypertensive medication adherence over 24 months in adolescents with chronic kidney disease (CKD).

Methods: Adolescents (N = 97, 11–20 years old) with CKD taking antihypertensive medication and their caregivers were recruited from three pediatric nephrology clinics. At baseline, adolescents and caregivers reported on adolescents’ executive functioning and caregivers reported on their adherence monitoring. Antihypertensive medication adherence was objectively assessed via electronic monitoring at baseline and every 6 months after for 24 months. Associations between executive functioning, caregiver monitoring, and longitudinal adherence were evaluated with linear mixed models. …

"There Was One Samuel": Possible Multiple Sources For The Samuel Narrative, Dan Belnap, Daniel L. Belnap

Faculty Publications

During the second day of Christ’s ministry to the New World, a curious event took place. Having taught and commented on a number of biblical texts, Christ then had Nephi3 present his own record for review.1 The inspection uncovered a missing event that Christ brought to the attention of the gathered disciples: “Verily I say unto you, I commanded my servant Samuel, the Lamanite, that he should testify unto this people, that at the day that the Father should glorify his name in me that there were many saints who should arise from the dead, and should appear unto many, …

Play, Chat, Date, Learn, And Suffer? Merton’S Law Of Unintended Consequences And Digital Technology Failures, Mark Rosenbaum, Gabby Walters, Karen Edwards J.D., Claudia Gonzalez, Germán Contreras Ramírez

Faculty Publications

No abstract provided.

The Effects Of Ceria Loading On Three-Way Catalysts For Passive Scr Operation, Calvin R. Thomas, Josh A. Pihl, Vitaly Y. Prikhodko, Michelle K. Kidder, Jochen A. Lauterbach, Todd J. Toops

Faculty Publications

Passive SCR systems, which employ both a three-way catalyst and SCR catalyst, are effective for the reduction of nitrogen oxide (NOx) emissions from lean burn gasoline engines. However, questions remain regarding the effect of three-way catalyst formulations on their performance in these systems. Here, Pd/CeOx/Al2O3 catalysts with variable CeOx loading were synthesized, characterized, and evaluated to determine the effects of CeOx on catalyst performance. While a small amount of ceria was beneficial for promoting essential reactions, excess ceria was detrimental due to the increase in oxygen storage capacity. Additionally, insights into potential reaction pathways for NH3 production were determined.

Mixing Optimization With Inward Flow Configuration Contra-Rotating Impeller, Baffle-Free Tank, P. Satjaritanun, J. R. Regalbuto, J. A. Regalbuto, N. Tippayawong, Sirivatch Shimpalee

Faculty Publications

In this study, pitched-blade, contra-rotating impeller, baffle-free tank with opposing inward flow is optimized using various designs of mixers derived from the Taguchi method. Mixing efficiency and torque are used to find the optimal design for the different specific gravities of solid particles employing in both experiments and CFD simulations. The analysis of signal-to-noise ratio shows that the impeller clearance and diameter are significant factors on the fluid flow and thus the mixing efficiency. In this study, 27 cases were studied to determine and report the optimal design parameters. A combination of CFD simulation with a strong design of experiment …

Using Generalizability Theory And The Erp Reliability Analysis (Era) Toolbox For Assessing Test-Retest Reliability Of Erp Scores Part 1: Algorithms, Framework, And Implementation, Scott A. Baldwin, Peter E. Clayson, Kalie A. Carbine, Joseph A. Olsen, Michael J. Larson

Faculty Publications

The reliability of event-related brain potential (ERP) scores depends on study context and how those scores will be used, and reliability must be routinely evaluated. Many factors can influence ERP score reliability; generalizability (G) theory provides a multifaceted approach to estimating the internal consistency and temporal stability of scores that is well suited for ERPs. G theory's approach possesses a number of advantages over classical test theory that make it ideal for pinpointing sources of error in observed scores. The current primer outlines the G-theory approach to estimating internal consistency (coefficients of equivalence) and test-retest reliability (coefficients of stability). This …

Online-Delivered Group And Personal Exercise Programs To Support Low Active Older Adults' Mental Health During The Covid-19 Pandemic: Randomized Controlled Trial, Mark R. Beauchamp, Ryan M. Hulteen, Geralyn R. Ruissen, Yan Liu, Ryan E. Rhodes, Colin M. Wierts, Katrina J. Waldhauser, Samantha H. Harden, Eli Puterman

Faculty Publications

Background: In response to the COVID-19 pandemic, experts in mental health science emphasized the importance of developing and evaluating approaches to support and maintain the mental health of older adults.

Objective: The aim of this study was to assess whether a group-based exercise program relative to a personal exercise program (both delivered online) and waitlist control (WLC) can improve the psychological health of previously low active older adults during the early stages of the COVID-19 pandemic.

Methods: The Seniors COVID-19 Pandemic and Exercise (SCOPE) trial was a 3-arm, parallel randomized controlled trial conducted between May and September 2020 in which …

Production Of Pure Vanadium: Industry Review And Feasibility Study Of Electron Beam Melt Refining Of V–Al Alloys, Devin Rappleye, Rob Haun

Faculty Publications

The vanadium industry has experienced significant change over the last two decades with the emergence of vanadium redox flow batteries for grid-level energy storage, the growing demand for high-strength steel, and the selection of vanadium as a critical material in multiple countries. This review presents the status of the vanadium industry examining production processes and detailing facilities. The available information for each producer is presented including vanadium products and capacity. The production of pure vanadium is identified as a potential vulnerability for some nations where vanadium metal is needed in small, yet strategic, applications and globally only two producers of …

Seasonal Variation Of Multiple-Muon Cosmic Ray Air Showers Observed In The Nova Detector Detector On The Surface, M. A. Acero, P. Adamson, L. Aliaga, N. Anfimov, A. Antoshkin, E. Arrieta-Diaz, L. Asquith, A. Aurisano, A. Back, C. Backhouse, M. Baird, N. Balashov, P. Baldi, B. A. Bambah, S. Bashar, K. Bays, R. Bernstein, V. Bhatnagar, B. Bhuyan, J. Bian, Roberto Petti, Et. Al.

Faculty Publications

We report the rate of cosmic ray air showers with multiplicities exceeding 15 muon tracks recorded in the NOvA Far Detector between May 2016 and May 2018. The detector is located on the surface under an overburden of 3.6 meters water equivalent. We observe a seasonal dependence in the rate of multiple-muon showers, which varies in magnitude with multiplicity and zenith angle. During this period, the effective atmospheric temperature and surface pressure ranged between 210 K and 230 K and 940 mbar and 990 mbar, respectively; the shower rates are anticorrelated with the variation in the effective temperature. The variations …