Digital Commons Network^™

Small-Scale Testing Of Passive Fire Protection Systems For Structures On The Wildland-Urban Interface, Makenzie Wilson, Thomas H. Fletcher, Taylor J. Sorensen

Faculty Publications

The average intensity and frequency of wildland fires have been on the rise over the years due to climate change. This, in combination with recent expansion and growth of rural areas, has led to an increased risk of wildfire damage for structures in the Wildland-Urban Interface (WUI). This paper proposes a permanent passive fire protection system that is built into the structure. A flame-resistant material would be attached to the sheathing underneath the roofing and siding material. This system would allow the easily replaceable exterior components of the structure to burn while leaving the interior of the structure protected. Small-scale …

Discovering Your Family In Digital Libraries, Jeremy Myntti

Faculty Publications

Presentation on using digital libraries in family history research for the BYU Family History Library webinar series.

From Crisis Management To Multi-Level Interinstitutional Partnerships: Development Of The Southeastern Conference Deans Nursing Coalition, Jeannette O. Andrews Phd, Rn, Faan, Victoria Niederhauser, Julie Sanford, Suzanne Prevost, Demetrius Porche, Janie Heath, Pamela Jeffries, Nancy Fahrenwald

Faculty Publications

The Southeastern Conference (SEC) Nursing Dean's Coalition is a purposeful alliance organized to collaboratively address several challenges that arose during the COVID-19 pandemic. Over the last three years, this strategic team of academic leaders has evolved from a crisis response team to a multidimensional support team, leveraging both individual and collective strengths, to provide several benefits to the dean members, as well as other SEC nursing faculty members, students, and institutions. Participation has grown from the original 12 deans to engage a broader team of associate deans and nurse leaders in faculty development, research, service, and diversity, equity, and inclusion. …

Leveraging Cultural Wealth, Identities And Motivation: How Diverse Intersectional Groups Of Low-Income Undergraduate Stem Students Persist In Collegiate Stem Environments, Raeshan D. Davis, Zakiya Wilson-Kennedy

Faculty Publications

Grounded in a conceptual framework incorporating intersectionality, motivation, self-determination, and self-efficacy, this empirical study investigated how individuals’ identities, mindsets, and resources in educational environments intentionally cultivated to support their decision-making, development, and connections in the science community, can significantly increase the recruitment, persistence, and success of low-income, academically talented science students from diverse backgrounds. Several factors—academic performance in coursework, self-image, self-agency, financial support, and social integration in the science culture—continue to significantly impact student retention and persistence in STEM disciplines. Many of these factors are negatively affected based on a students’ intersecting identities, which can be detrimental to their academic …

Basic Human Values Drive Food Choice Decision-Making In Different Food Environments Of Kenya And Tanzania, Christine E. Blake Ph.D., Rd, Eva C. Monterrosa, Krystal K. Rampalli, Abdullah Nurus Salam Khan, Ligia I. Reyes, Shiny Deepika Drew, Paula Dominguez-Salas, Salome A. Bukachi, Mariah Ngutu, Edward A. Frongillo Ph.D., Elyse Iruhiriye, Amy Webb Girard

Faculty Publications

Increased access to a variety of foods in low-and-middle-income countries (LMICs) has led to greater autonomy in food choice decision-making. Autonomy allows individuals to make decisions through negotiation of considerations in ways that are consistent with basic values. The aim of this study was to identify and describe how basic human values drive food choice in two diverse populations with transitioning food environments living in the neighboring East African countries of Kenya and Tanzania. Secondary data analysis was carried out on focus group discussions conducted with men and women in Kenya (n = 28) and Tanzania (n = 28) as …

Computation Of High-Order Sensitivities Of Model Responses To Model Parameters—I: Underlying Motivation And Current Methods, Dan Gabriel Cacuci

Faculty Publications

The mathematical/computational model of a physical system comprises parameters and independent and dependent variables. Since the physical system is seldom known precisely and since the model’s parameters stem from experimental procedures that are also subject to uncertainties, the results predicted by a computational model are imperfect. Quantifying the reliability and accuracy of results produced by a model (called “model responses”) requires the availability of sensitivities (i.e., functional partial derivatives) of model responses with respect to model parameters. This work reviews the basic motivations for computing high-order sensitivities and illustrates their importance by means of an OECD/NEA reactor physics benchmark, which …

Computation Of High-Order Sensitivities Of Model Responses To Model Parameters—Ii: Introducing The Second-Order Adjoint Sensitivity Analysis Methodology For Computing Response Sensitivities To Functions/Features Of Parameters, Dan Gabriel Cacuci

Faculty Publications

This work introduces a new methodology, which generalizes the extant second-order adjoint sensitivity analysis methodology for computing sensitivities of model responses to primary model parameters. This new methodology enables the computation, with unparalleled efficiency, of second-order sensitivities of responses to functions of uncertain model parameters, including uncertain boundaries and internal interfaces, for linear and/or nonlinear models. Such functions of primary model parameters customarily describe characteristic “features” of the system under consideration, including correlations modeling material properties, flow regimes, etc. The number of such “feature” functions is considerably smaller than the total number of primary model parameters. By enabling the computations …

The Town That Built Its Own River: La Plaza Del Cerro At Taos County New Mexico, José A. Rivera Ph.D

Faculty Publications

Cerro is an unincorporated community in Taos County, New Mexico, and is situated near New Mexico State Highway 522 heading north to the Colorado border. Nearby is Cerro de Guadalupe, a peak that has an elevation of 8,796 feet and Cerro at 7,490 feet. The connection to Guadalupe Mountain gave the town its original name as “La Plaza del Cerro de Guadalupe.” Cerro was established in the early 1850s by settlers who arrived from nearby Questa and Taos. By itself, Guadalupe Mountain did not provide sufficient water to sustain an agrarian economy based on farming and livestock ranching as was …

The Somalia Affair And The Transformation Of Canadian Military Justice, Preston Lim

Faculty Publications

No abstract provided.

Key Elements Of A File Format Strategy, Tyler Thorsted

Faculty Publications

Within the Digital Preservation Community there are many references to policies on file formats, acceptable file formats, preservation policies and strategies, risk matrices, and action plans. All have the intention of defining and describing file formats and guiding decisions on which formats to preserve how, and when. My team and I originally created a File Format Action Plan, which was later migrated from OneNote to Confluence and then included more strategic plans for hundreds of file formats. This paper explores which key elements should be included in an effective file format strategy and the different ways such data can be …

Utilizing Low-Cost Sensors To Monitor Indoor Air Quality In Mongolian Gers, Callum Flowerday, Jaron C. Hansen, Phil Lundrigan, Christopher Kitras

Faculty Publications

Air quality has important climate and health effects. There is a need, therefore, to monitor air quality both indoors and outdoors. Methods of measuring air quality should be cost-effective if they are to be used widely, and one such method is low-cost sensors (LCS). This study reports on the use of LCSs in Ulaanbataar, Mongolia to measure PM_2.5 concentrations inside yurts or “gers”. Some of these gers were part of a non-government agency (NGO) initiative to improve insulating properties of these housing structures. The goal of the NGO was to decrease particulate emissions inside the gers; a secondary result …

Analog Analogies: Intel V. Hamidi And The Future Of Trespass To Chattels, Maureen E. Brady, James Y. Stern

Faculty Publications

A symposium on great torts cases of the twenty-first century must include Intel Corp. v. Hamidi, the canonical case about whether unwanted e-mail spam sent to a company’s server could give rise to a trespass to chattels claim. While much has been written about Intel, in this Essay, we argue that Intel is as much of a classic for what it reveals about the old-fashioned tort as it is for its more closely examined ruling on “cybertrespass.” The dueling personal property analogies chosen by the majority and dissenting opinions in Intel reveal basic and fundamental disagreements about what …

Bacterial Extraction And Concentration From Blood Through Filtration Processes, Ryan L. Wood, Rebecca Prymak, Evelyn Welling, Alayna Bedwell, Jordan T. Wood, Damian E. Teasley, Magdalena Crofts, Hope Callister Anderson, Clifton M. Anderson, W Cameron Beard, Jacob Stepan, Alexandra Carter, William G. Pitt

Faculty Publications

Blood stream infections (BSIs) are challenging to rapidly and precisely diagnose. Current clinical diagnostic methods for BSI identification require culturing the blood sample for many hours prior to identifying the bacteria and possible antibiotic resistance. Removing the culturing step from the bacterial identification process of a BSI provides a significant reduction in the processing time, but shifts the rate-limiting step from the growth time to the concentration procedure, since CFU levels in clinical blood samples can be as low as 10 CFU/mL in blood. This study developed a novel whole blood filtration method to concentrate bacteria from a BSI without …

Transferrin-Targeted Liposomes In Glioblastoma Therapy: A Review, Paul Kawak, Nour M Al Sawaftah, William G. Pitt, Ghaleb A. Husseini

Faculty Publications

Glioblastoma (GBM) is a highly aggressive brain tumor, and its treatment is further complicated by the high selectivity of the blood–brain barrier (BBB). The scientific community is urgently seeking innovative and effective therapeutic solutions. Liposomes are a promising new tool that has shown potential in addressing the limitations of chemotherapy, such as poor bioavailability and toxicity to healthy cells. However, passive targeting strategies based solely on the physicochemical properties of liposomes have proven ineffective due to a lack of tissue specificity. Accordingly, the upregulation of transferrin receptors (TfRs) in brain tissue has led to the development of TfR-targeted anticancer therapeutics. …

Recommended Separation Distances For 1.3 Ammunition And Explosives, Clint Guymon, Ming Liu, Josephine Covino

Faculty Publications

Separation Distances are used throughout the world to protect people and assets from the potential hazardous effects from propellants, explosives, and pyrotechnics. The current separation distances for Hazard Division (HD) 1.3 substances and articles used in the United States, in some cases, may not adequately protect against the effects from heat flux and debris when those substances and articles are ignited in a confined structure. Multiple tests in such a confined scenario with HD 1.3 substances have shown that the heat flux and debris hazards could result in injury at distances beyond the current specified explosives safety separation distance (ESSD). …

Simultaneous Multistep Transformer Architecture For Model Predictive Control, Junho Park, Mohammad Reza Babaei, Samuel Arce Munoz, Ashwin N. Venkat, John Hedengren

Faculty Publications

Transformer neural networks have revolutionized natural language processing by effectively addressing the vanishing gradient problem. This study focuses on applying Transformer models to time-series forecasting and customizing them for a simultaneous multistep-ahead prediction model in surrogate model predictive control (MPC). The proposed method showcases improved control performance and computational efficiency compared to LSTM-based MPC and one-step-ahead prediction models using both LSTM and Transformer networks. The study introduces three key contributions: (1) a new MPC system based on a Transformer time-series architecture, (2) a training method enabling multistep-ahead prediction for time-series machine learning models, and (3) validation of the enhanced time …

Don't Fear The Artificial Intelligence: A Systematic Review Of Machine Learning For Prostate Cancer Detection In Pathology, Aaryn Frewing, Alexander B. Gibson, Richard Robertson, Paul Urie, Dennis Della Corte

Faculty Publications

The adoption of whole slide image (WSI) scanners in clinical practice was accelerated by US Food and Drug Administration approval in 2017, which allowed primary pathologic diagnoses to be made on scanned images. Images in the digital domain allow the application of pathology artificial intelligence (AI), including clinical decision support with algorithms performing specific diagnoses.1,2 These algorithms, if trained properly, could go beyond the ability of human observation to detect and quantify features that are not recognizable by human perception.1,3,4

Developing An Ethical Framework-Guided Instrument For Assessing Bias In Ehr-Based Big Data Studies: A Research Protocol, Shan Qiao Ph.D., George Khushf, Xiaoming Li, Jiajia Zhang Ph.D., Bankole Olatosi Ph.D.

Faculty Publications

Introduction The emergence of Big Data health research has exponentially advanced the fields of medicine and public health but has also faced many ethical challenges. One of most worrying but still under-researched aspects of the ethical issues is the risk of potential biases in data sets (eg, electronic health records (EHR) data) as well as in the data curation and acquisition cycles. This study aims to develop, refine and pilot test an ethical framework-guided instrument for assessing bias in Big Data research using EHR data sets.

Methods and analysis Ethical analysis and instrument development (ie, the EHR bias assessment guideline) …

Determination Of A Surrogate For Plutonium Electrorefining, Greg Chipman, Bryant Johnson, Suhee Choi, Chao Zhang, Michael Simpson, Devin Rappleye

Faculty Publications

Conducting research experiments on plutonium electrorefining is difficult due to the significant hazards and regulations associated with nuclear materials. Finding a surrogate for plutonium electrorefining studies would enable more fundamental research to be conducted. Potential surrogates were first identified by determining the physical properties required to conduct electrorefining at the same conditions commonly used in plutonium electrorefining, a molten metal and molten CaCl₂ at 1123 K. Ce-CeCl₃, In-InCl₃, and Pb-PbCl₂ were the only potential surrogates identified using these constraints. Sn-SnCl₂ was also tested at these same conditions. More potential surrogates were identified by …

Cdk8 And Cdk19: Positive Regulators Of Signal-Induced Transcription And Negative Regulators Of Mediator Complex Proteins, Mengqian Chen, Jing Li, Li Zhang, Lili Wang, Chen Cheng, Hao Ji, Serena Altilia, Xiaokai Ding, Guoshuai Cai, Diego Altomare, Michael Shtutman, Stephanie D. Byrum, Samuel G. Mackintosh, Alexey Feoktistov, Nataliya Soshnikova, Vladislav A. Mogila, Victor Tatarskiy, Maksim Erokhin, Darya Chetverina, Angga Prawira, Yi Ni, Stephan Urban, Campbell Mcinnes, Eugenia Broude, Igor Roninson

Faculty Publications

We have conducted a detailed transcriptomic, proteomic and phosphoproteomic analysis of CDK8 and its paralog CDK19, alternative enzymatic components of the kinase module associated with transcriptional Mediator complex and implicated in development and diseases. This analysis was performed using genetic modifications of CDK8 and CDK19, selective CDK8/19 small molecule kinase inhibitors and a potent CDK8/19 PROTAC degrader. CDK8/19 inhibition in cells exposed to serum or to agonists of NFκB or protein kinase C (PKC) reduced the induction of signal-responsive genes, indicating a pleiotropic role of Mediator kinases in signal-induced transcriptional reprogramming. CDK8/19 inhibition under basal conditions initially downregulated a small …

Changes In Medicaid Fee-For-Service Benefit Design For Substance Use Disorder Treatment During The Opioid Crisis, 2014 To 2021, Angela Shoulders, Christina Andrews, Melissa A. Westlake, Amanda J. Abraham, Colleen M. Grogan

Faculty Publications

Importance: Medicaid is the largest payer of substance use disorder treatment in the US and plays a key role in responding to the opioid epidemic. However, as recently as 2017, many state Medicaid programs still did not cover the full continuum of clinically recommended care. Objective: To determine whether state Medicaid fee-for-service (FFS) programs have expanded coverage and loosened restrictions on access to substance use disorder treatment in recent years. Design, Setting, and Participants: In 2014, 2017, and 2021, a survey on coverage for substance use disorder treatment was conducted among state Medicaid programs and the District of Columbia with …

The Association Between Covid-19 Preventive Behaviors And Mental Health Conditions, Elizabeth Wachira, Bhakti Chavan, Carolyn Nganga-Good, Caroline Kingori

Faculty Publications

Our findings highlight that individuals with mental health conditions reported more psychological distress. Specifically, feeling depressed, anxious, lonely, and hopeless were triggered and exacerbated as a result of the pandemic and may have long-term effects on general well-being and productivity. Therefore, our findings have important implications on the need to include mental health promotion as part of pandemic response efforts. This includes developing policies and allocating funding so as to ensure sustainable mental health interventions and support, public and provider education on the importance of screening for mental health issues.

The Dynamic Nature Of Wrack: An Investigation Into Wrack Movement And Impacts On Coastal Marshes Using Suas, Grayson R. Morgan, Daniel R. Morgan, Cuizhen Wang, Michael E. Hodgson, Steven R. Schill

Faculty Publications

This study investigates the use of small unoccupied aerial systems (sUAS) as a new remote sensing tool to identify and track the spatial distribution of wrack on coastal tidal marsh systems. We used sUAS to map the wrack movement in a Spartina alterniflora-dominated salt marsh monthly for one year including before and after Hurricane Isaias that brought strong winds, rain, and storm surge to the area of interest in August 2020. Flight parameters for each data collection mission were held constant including collection only during low tide. Wrack was visually identified and digitized in a GIS using every mission orthomosaic …

That Ye Might Feel And See: Touch In The First Day Of Christ's Ministry, Dan L. Belnap

Faculty Publications

No abstract provided.

Seeking Sacagawea: A Comparison Of The Accounts Of Bird Woman’S Birth, Life, And Death, Jay H. Buckley, Maren Burgess

Faculty Publications

On Saturday August 17, 1806, Captain William Clark of the Lewis and Clark Expedition recorded: "we ... took our leave of T. Chabono, his Snake Indian wife and their Son Child who had accompanied us on our rout to the pacific Ocean in the Capacity of interpreter and interpretes." This "Snake Indian wife" Sacagawea, also known as Sacajawea or Sakakawea, had proven her worth as a significant contributor to the Expedition not only through her services as "interpretes" but also through her diplomatic skills with Natives, knowledge of the land, food gathering abilities, and the symbol of peace she represented …

Large-Scale Nonequilibrium Molecular Studies Of Thermal Hydrate Dissociation, Meisam Adibifard, Olufemi Olorode

Faculty Publications

The energy content of methane hydrate reservoirs (MHRs) is at least twice that of conventional fossil fuels. So, there is considerable interest in their commercial development by heating, among other dissociation mechanisms. However, a few researchers have highlighted the potentially uncontrollable release of methane from MHRs, which could occur because of global warming. Therefore, it is crucial to understand the kinetics of thermal hydrate dissociation to safely develop these resources and prevent the release of this greenhouse gas into the environment. Although there have been several molecular studies of thermal dissociation, most of these use small simulation domains that cannot …

Semi-Automated Techniques And Tools For Efficiency: The Case Of Etd Cataloging, Nicole Lewis

Faculty Publications

Technological advances in the library industry have opened doors for new approaches and techniques for efficiently managing, manipulating, and remediating metadata. However, the thought of automation can often bring visions of garbage in the catalog or, worse, job consolidation or loss. With the right balance of automation and manual review, catalogers and metadata experts can optimize workflows for efficiency and quality. This frees up time for other essential projects. Developing efficiency skills may also help increase productivity and excellence in current job duties and provide job advancement opportunities regardless of background. Using an ETD cataloging workflow as a case study, …

Liposomes For The Treatment Of Brain Cancer—A Review, Richu Raju, Waad H. Abuwatfa, William G. Pitt, Ghaleb A. Husseini

Faculty Publications

Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate targeted delivery across the blood–brain barrier (BBB). Additionally, strategies have been explored to synthesize liposomes that respond to internal and/or external stimuli to release their payload controllably. Although research into liposomes for brain cancer treatment is still in its infancy, these systems have great potential to fundamentally change the drug delivery landscape. This review paper attempts to consolidate relevant literature regarding the delivery to the brain using nanocarriers, particularly liposomes. The paper first briefly explains conventional treatment modalities for cancer, followed …

A Review On Membrane Fouling Prediction Using Artificial Neural Networks (Anns), Waad H. Abuwatfa, Nour Al Sawaftah, Naif Darwish, William G. Pitt, Ghaleb A. Husseini

Faculty Publications

Membrane fouling is a major hurdle to effective pressure-driven membrane processes, such as microfiltration (MF), ultrafiltration (UF), nanofiltration (NF), and reverse osmosis (RO). Fouling refers to the accumulation of particles, organic and inorganic matter, and microbial cells on the membrane’s external and internal surface, which reduces the permeate flux and increases the needed transmembrane pressure. Various factors affect membrane fouling, including feed water quality, membrane characteristics, operating conditions, and cleaning protocols. Several models have been developed to predict membrane fouling in pressure-driven processes. These models can be divided into traditional empirical, mechanistic, and artificial intelligence (AI)-based models. Artificial neural networks …

The Hidden Power Of “Thank You”: Exploring Aspects, Expressions, And The Influence Of Gratitude In Religious Families, Joe M. Chelladurai, Loren D. Marks, David C. Dollahite, Heather H. Kelley, David B. Allsop

Faculty Publications

Gratitude has been extensively studied over the past two decades. Among several predictors, aspects of religiosity and spirituality have been consistent predictors of gratitude. To explore the religious motivations and processes that foster the practice of gratitude, we undertook a systematic thematic analysis using interview data from a national qualitative project of 198 highly religious families. Participants (n = 476) included mothers, fathers, and children from various socioeconomic backgrounds and from diverse religious, racial, and ethnic backgrounds in the United States of America. Semi-structured interviews were conducted in the participants’ homes. Data for this study were analyzed using a team-based …