Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (2775)
- Engineering (2198)
- Law (1969)
- Medicine and Health Sciences (1850)
- Arts and Humanities (1763)
-
- Physical Sciences and Mathematics (1607)
- Business (1234)
- Public Health (1086)
- Life Sciences (906)
- Chemical Engineering (846)
- Education (810)
- Religion (747)
- Mechanical Engineering (605)
- Library and Information Science (571)
- Public Health Education and Promotion (468)
- Physics (452)
- Psychology (450)
- Electrical and Computer Engineering (444)
- Linguistics (406)
- Computer Sciences (381)
- English Language and Literature (325)
- History (305)
- Accounting (301)
- Biology (301)
- Astrophysics and Astronomy (274)
- Nursing (271)
- Finance and Financial Management (269)
- Biblical Studies (268)
- Other Social and Behavioral Sciences (264)
- Mormon Studies (254)
- Institution
-
- Brigham Young University (6151)
- University of South Carolina (4451)
- William & Mary Law School (558)
- Louisiana State University (498)
- Andrews University (471)
-
- San Jose State University (355)
- University of Missouri School of Law (310)
- Santa Clara Law (211)
- University of North Carolina School of Law (196)
- The University of Southern Mississippi (179)
- Case Western Reserve University School of Law (157)
- Florida International University College of Law (129)
- University of South Dakota (128)
- St. John's University School of Law (99)
- University of New Hampshire (93)
- Rollins College (89)
- Luther Seminary (86)
- Marquette University Law School (85)
- Stephen F. Austin State University (85)
- University of Northern Iowa (85)
- Linfield University (75)
- Villanova University Charles Widger School of Law (51)
- National Louis University (44)
- Hope College (36)
- East Texas A&M University (34)
- University of Maine School of Law (33)
- Denison University (31)
- Fordham University (28)
- University of Southern Maine (20)
- Air Force Institute of Technology (17)
- Keyword
-
- Chemical Engineering (196)
- Public Health (142)
- Children (134)
- Physical activity (130)
- Education (124)
-
- Humans (111)
- History (110)
- Religion (108)
- COVID-19 (101)
- United States (89)
- Electrochemical electrodes (80)
- Mental health (79)
- Gender (78)
- Computer Science and Engineering (69)
- Law (68)
- Female (67)
- Exercise (64)
- Book of Mormon (63)
- Mathematics (63)
- Obesity (63)
- Health (61)
- Marriage (59)
- Archaeology (58)
- Electrochemistry (57)
- UAV (57)
- Adolescents (56)
- Biblical Studies (56)
- HIV (56)
- Higher education (55)
- Inflammation (55)
- Publication Year
- File Type
Articles 1411 - 1440 of 14851
Full-Text Articles in Entire DC Network
Looking Back To Look Forward: Exploring Crenshaw’S Political, Structural, And Representational Intersectionality In Sport, Allison Anders Ph.D., James M. Devita, Leslee A. Fisher, Chris Corr, Christina L. Myers
Looking Back To Look Forward: Exploring Crenshaw’S Political, Structural, And Representational Intersectionality In Sport, Allison Anders Ph.D., James M. Devita, Leslee A. Fisher, Chris Corr, Christina L. Myers
Faculty Publications
Engaging with Kimberlé Crenshaw’s concept of intersectionality, the authors (re)turn to its genesis in critical race theory (CRT) and specifically, its forms of structural intersectionality, political intersectionality, and representational intersectionality. Discussing each form in relation to contemporary issues in sport that Black women and women of Color navigate, they argue that Crenshaw’s intersectionality provides additional compelling layers of engagement with existing intersectional scholarship and scholarship about activism in sport, invites structural and discursive change through intersectional policies and practice, and promotes coalition building toward intersectional racial justice in sport.
Exiting Inflation With A Smooth Scale Factor, Harry Oslislo, Brett Altschul
Exiting Inflation With A Smooth Scale Factor, Harry Oslislo, Brett Altschul
Faculty Publications
The expectation that the physical expansion of space occurs smoothly may be expressed mathematically as a requirement for continuity in the time derivative of the metric scale factor of the Friedmann–Robertson–Walker cosmology. We explore the consequences of imposing such a smoothness requirement, examining the forms of possible interpolating functions between the end of inflation and subsequent radiation- or matter-dominated eras, using a straightforward geometric model of the interpolating behavior. We quantify the magnitude of the cusp found in a direct transition from the end of slow-roll inflation to the subsequent era, analyze the validity of several smooth interpolator candidates, and …
The Chatgpt Artificial Intelligence Chatbot: How Well Does It Answer Accounting Assessment Questions?, David A. Wood, Ryan D. Sommerfeldt, Muskan P. Achhpilia, Mollie T. Adams, Sanaz Aghazadeh, William G. Heninger, Jeffrey Pickerd, Jon Kerr
The Chatgpt Artificial Intelligence Chatbot: How Well Does It Answer Accounting Assessment Questions?, David A. Wood, Ryan D. Sommerfeldt, Muskan P. Achhpilia, Mollie T. Adams, Sanaz Aghazadeh, William G. Heninger, Jeffrey Pickerd, Jon Kerr
Faculty Publications
ChatGPT, a language-learning model chatbot, has garnered considerable attention for its ability to respond to users’ questions. Using data from 14 countries and 186 institutions, we compare ChatGPT and student performance for 28,085 questions from accounting assessments and textbook test banks. As of January 2023, ChatGPT provides correct answers for 56.5 percent of questions and partially correct answers for an additional 9.4 percent of questions. When considering point values for questions, students significantly outperform ChatGPT with a 76.7 percent average on assessments compared to 47.5 percent for ChatGPT if no partial credit is awarded and 56.5 percent if partial credit …
Establishment Of A Birth-To-Education Cohort Of 1 Million Palestinian Refugees Using Electronic Medical Records And Electronic Education Records, Zeina Jamaluddine, Akihiro Seita, Ghada Ballout, Hussam Al-Fudoli, Gloria Paolucci, Shatha Albaik, Rami Ibrahim, Miho Sato, Hala Ghattas Ph.D., Oona M.R. Campbell
Establishment Of A Birth-To-Education Cohort Of 1 Million Palestinian Refugees Using Electronic Medical Records And Electronic Education Records, Zeina Jamaluddine, Akihiro Seita, Ghada Ballout, Hussam Al-Fudoli, Gloria Paolucci, Shatha Albaik, Rami Ibrahim, Miho Sato, Hala Ghattas Ph.D., Oona M.R. Campbell
Faculty Publications
Introduction
By linking datasets, electronic records can be used to build large birth-cohorts, enabling researchers to cost-effectively answer questions relevant to populations over the life-course. Currently, around 5.8 million Palestinian refugees live in five settings: Jordan, Lebanon, Syria, West Bank, and Gaza Strip. The United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) provides them with free primary health and elementary-school services. It maintains electronic records to do so.
We aimed to establish a birth cohort of Palestinian refugees born between 1st January 2010 and 31st December 2020 living in five settings by linking mother …
Creating An Inclusive Metadata Policy, Nicole Lewis, Jeremy Myntti
Creating An Inclusive Metadata Policy, Nicole Lewis, Jeremy Myntti
Faculty Publications
The BYU Library is creating an Inclusive Metadata Policy for metadata creators to use when creating and remediating descriptions to be more inclusive. Accompanying the policy is a companion document with recommendations and examples, including links to many external resources. In addition to working with stakeholders in the library to develop the policy, we consulted with the University’s Office of Belonging. This presentation describes the process we used to undertake the creation of the library policy and recommendations document.
Law And Its Limits: Ethical Issues In Mary Shelly's Frankenstein Or, The Modern Prometheus, David S. Caudill
Law And Its Limits: Ethical Issues In Mary Shelly's Frankenstein Or, The Modern Prometheus, David S. Caudill
Faculty Publications
The law and literature movement is frequently associated with the use of literary images of law as a point of reflection upon the ethical obligations of lawyers. Mary Shelley’s Frankenstein (1818)—the story of a young scientist whose unorthodox experiments end up creating the famed “monster”—is not, at first glance, a likely candidate for that enterprise. However, Dr. Frankenstein’s ambition and ruthless pursuit of knowledge has become a contemporary image of science out of control and the need for ethical limitations on scientific progress. Consequently, the novel raises currently important issues of regulating science and technology. Given the lawyer’s ethical obligation …
Telling Stories In Noise: The Impact Of Background Noises On Spoken Language For People With Aphasia, Tyson G. Harmon, Brenna Scadden Nelson, Christopher Dromey, Kirsten Dixon Clawson
Telling Stories In Noise: The Impact Of Background Noises On Spoken Language For People With Aphasia, Tyson G. Harmon, Brenna Scadden Nelson, Christopher Dromey, Kirsten Dixon Clawson
Faculty Publications
Purpose: Determine how different background noise conditions affect the spoken language of participants with aphasia during a story retell task.
Method: Participants included 11 adults with mild to moderate aphasia and 11 age- and gender-matched controls. Participants retold stories in a silent baseline and five background noise conditions (conversation, monologue, phone call, cocktail, pink noise). Dependent measures of speech acoustics (fundamental frequency, mean intensity), speech fluency (speech rate, disfluent words), and language production (correct information units, lexical errors, lexical diversity, and cohesive utterances) were compared between groups and across conditions.
Results: Background noise resulted in higher fundamental frequency (F0 …
Physiological Arousal, Attentiveness, Emotion, And Word Retrieval In Aphasia: Effects And Relationships, Tyson G. Harmon, Angela Johnson, Vivian Ward, Shawn Nissen
Physiological Arousal, Attentiveness, Emotion, And Word Retrieval In Aphasia: Effects And Relationships, Tyson G. Harmon, Angela Johnson, Vivian Ward, Shawn Nissen
Faculty Publications
Purpose: To (a) compare physiological arousal and attentiveness during a confrontational naming task between participants with aphasia and a control group across four conditions that varied according to emotionality of presented stimuli and (b) explore relationships among physiological arousal, attentiveness, perceived arousal, and naming performance. We hypothesized that participants with aphasia would show lower levels of arousal and attentiveness than control participants and that emotional conditions would lead to increased physiological arousal and attentiveness.
Method: Eight participants with aphasia and 15 control participants completed a confrontational naming task under positive, negative, and neutral conditions and rated their perceived arousal after …
Could Our Universe Have Been Initiated Intentionally: An Epistemological Framework, Dan Broadbent
Could Our Universe Have Been Initiated Intentionally: An Epistemological Framework, Dan Broadbent
Faculty Publications
The possibility that our universe was initiated intentionally is a compelling philosophical and scientific question that can be evaluated probabilistically based on four primary considerations: fine-tuning in our universe, hypotheses about the multiverse, the likelihood that intelligent life may be able to initiate a universe, and the possibility that we live in a simulation. This paper offers an equation analogous to the noteworthy Drake equation that is intended to be used as a structured thought experiment to help identify factors related to the initiation of our universe and to facilitate examining each in terms of what we know, do not …
Utilizing Student Workers For Digital Commons Projects, Ellen Amatangelo, Elizabeth Parret
Utilizing Student Workers For Digital Commons Projects, Ellen Amatangelo, Elizabeth Parret
Faculty Publications
This lightning talk was presented by the Scholarly Communications Coordinator and the Scholarly Communications Student Supervisor from Brigham Young University at the Digital Commons North American Conference 2023. It provides an overview of how student workers at the BYU Library are involved in Digital Commons projects and discusses the types of projects and processes that students work on, including an outline of student supervisor responsibilities. The purpose of the presentation is to get other Digital Commons administrators excited about expanding the possibilities of their repositories by collaborating with student workers.
Neutronic Analysis Of The Byu Molten Salt Micro Reactor, Collin Bradford, Edward Mercado, Braden Clayton, Lagrande Gunnell, Andrew Larsen, Matthew Memmott
Neutronic Analysis Of The Byu Molten Salt Micro Reactor, Collin Bradford, Edward Mercado, Braden Clayton, Lagrande Gunnell, Andrew Larsen, Matthew Memmott
Faculty Publications
Background: With the rising need for reliable and clean energy, researchers at Brigham Young University created a molten salt microreactor (MSMR) concept to help meet the world’s growing energy demands. The MSMR is rated at 45 MWth and is uniquely capable of passively dissipating all decay heat using conduction only.
Methods: This work presents the results of the simulated neutronic behavior of the MSMR using the Monte Carlo neutronics code OpenMC with the ENDF/B-VII.1 cross-section library at steady state conditions. The specific characteristics discussed in this work are: keff, power profile, axial and radial peak power factors, Doppler coefficient of …
Class Size Determination And Decision Making In Lis Online Education, Lucy Santos Green, Kim M. Thompson, Nicole A. Cooke
Class Size Determination And Decision Making In Lis Online Education, Lucy Santos Green, Kim M. Thompson, Nicole A. Cooke
Faculty Publications
The purpose of this study was to develop a national landscape of the decisions made by LIS programs regarding online course enrollment caps. Online education expands learning opportunities for all students and is particularly attractive to nontraditional students who are more likely to have employment and family obligations that make attending traditional face-to-face classes difficult. At the same time, online learning can exacerbate existing opportunity gaps between certain student groups, depending on how well-prepared students are for online learning. This survey methodology study investigated course enrollment caps and the reasons behind the limits placed by Master of Library and Information …
Word Choice: A Neglected But Key Skill For Ell Writers, Kristin Lems
Word Choice: A Neglected But Key Skill For Ell Writers, Kristin Lems
Faculty Publications
With all of the urgent, critical issues confronting education in general, and literacy practices in particular, why write a column on something as obscure as word choice? Word choice (sometimes called vocabulary choice or diction) often drops to the bottom of the “To Do” list for English as a Second Language (ESL), English, bilingual, and language arts teachers. Even when teachers are able to focus on writing to begin with (writing development is often the first thing cut when lessons run over), teachers of English language learners (ELLs) are too preoccupied with teaching grammar, spelling, organization, syntax, genres, and building …
Martin Luther On Praying The Psalms, Mary Jane Haemig
Martin Luther On Praying The Psalms, Mary Jane Haemig
Faculty Publications
No abstract provided.
Perceived Stress And Suicidal Ideation: The Role Of Dispositional Mindfulness, Emma H. Moscardini, Anthony Robinson, Jessica Gerner, Raymond P. Tucker
Perceived Stress And Suicidal Ideation: The Role Of Dispositional Mindfulness, Emma H. Moscardini, Anthony Robinson, Jessica Gerner, Raymond P. Tucker
Faculty Publications
Objectives: Extant literature suggests that dispositional mindfulness may reduce the impact perceived stress has on the severity of suicidal ideation (SI). Only one study has analyzed this question but did so with a cross-sectional design in a sample of undergraduate women. Methods: This study analyzed the potential moderating role of dispositional mindfulness on the relation between perceived stress and SI cross-sectionally and at one-week follow-up in a sample of US adults (N = 598) with a history of SI. Results: Results indicated that dispositional mindfulness and its facets were inversely related to perceived stress, SI severity at baseline, and SI …
Does Investment In Green Employee Development Climate Matter For Environmental Commitment And Green Well-Being? A Case Study Of A Palm Oil Company In Malaysia, Patricia Yinyin Lau, Sunyoung Park, Yen Chen Hsu, Bella Ya Hui Lien, Jo Ann Ho
Does Investment In Green Employee Development Climate Matter For Environmental Commitment And Green Well-Being? A Case Study Of A Palm Oil Company In Malaysia, Patricia Yinyin Lau, Sunyoung Park, Yen Chen Hsu, Bella Ya Hui Lien, Jo Ann Ho
Faculty Publications
Drawing on social exchange theory and stakeholder responses to corporate social responsibility model, this study aimed to examine if the cross-level impacts of perceived investment in green employee development climate (PIGED) on environmental commitment (EC) and green well-being (GWB) were mediated by green person-job fit and green growth need strength. We collected a total of 412 employees and 80 operating units from a leading palm-oil company in Malaysia. The multilevel regression analysis found the cross-level effects of PIGED on EC and GWB that were partially mediated by green person-job fit and green growth need strength. Due to incomplete understanding of …
Strategies Elementary School Children Use To Influence Mothers' Food Purchasing Decisions, Nazratun N. Monalisa, Edward A. Frongillo Ph.D., Christine E. Blake Ph.D., Rd, Susan E. Steck, Robin B. Dipietro
Strategies Elementary School Children Use To Influence Mothers' Food Purchasing Decisions, Nazratun N. Monalisa, Edward A. Frongillo Ph.D., Christine E. Blake Ph.D., Rd, Susan E. Steck, Robin B. Dipietro
Faculty Publications
This study aimed to understand the strategies elementary-school-aged children used to influence mothers' food purchasing decisions. Semi-structured qualitative interviews were conducted with 40 children aged 6–11 years and their mothers living in South Carolina. Strategies to influence mothers' food purchases were collected from children and their mothers separately. The interviews were audio-recorded, transcribed verbatim, and open-coded. The constant comparative method was used for data analysis. Coding matrices were used to compare children's and mothers' responses on the children's strategies. Children reported 157 instances of 25 distinct strategies to influence mothers' purchasing decisions. Mothers had concordance with 83 instances of these …
Geographic Differences In The Magnitude Of Black-White Disparities In Having Obesity, Steven A. Cohen, Monique J. Brown, Furong Xu, Caitlin C. Nash, Mary L. Greaney
Geographic Differences In The Magnitude Of Black-White Disparities In Having Obesity, Steven A. Cohen, Monique J. Brown, Furong Xu, Caitlin C. Nash, Mary L. Greaney
Faculty Publications
Background
Obesity disparities in the United States are well documented, but the limited body of research suggests that geographic factors may alter the magnitude of these disparities. A growing body of evidence has identified a “rural mortality penalty” where morbidity and mortality rates are higher in rural than urban areas, even after controlling for other factors. Black-White differences in health and mortality are more pronounced in rural areas than in urban areas.
Objective
Therefore, the purpose of this study was to explore how rural-urban status and region moderate Black-White health disparities in obesity.
Methods
Data were abstracted from the 2012 …
Understanding Commitment Of Local Food Banks, Faith-Based Organizations, And Schools To Provide Nongovernment Food Programs, Eliza M. Fishbein, Edward A. Frongillo Ph.D., Sharraf Samin, Audrey L. Richards, Christine E. Blake Ph.D., Rd, Ruth P. Saunders, Cheri J. Shapiro
Understanding Commitment Of Local Food Banks, Faith-Based Organizations, And Schools To Provide Nongovernment Food Programs, Eliza M. Fishbein, Edward A. Frongillo Ph.D., Sharraf Samin, Audrey L. Richards, Christine E. Blake Ph.D., Rd, Ruth P. Saunders, Cheri J. Shapiro
Faculty Publications
Background: Nongovernment food assistance is typically provided to families by faith-based organizations, schools, and food banks. Community organizations appear to be strongly committed to these programs, but little is known about the basis for this commitment. Objectives: The aim of this study was to examine the values and identities of community organizations to understand the reasons for their commitment to providing nongovernment food assistance. Methods: Thirty-three in-depth interviews were conducted with 36 leaders at faith-based organizations (19 participants), schools (14 participants), and a local food bank (3 participants) in South Carolina. Observations were made, and informational documents (e.g., flyers and …
Integrating Clinical Cancer And Ptm Proteomics Data Identifies A Mechanism Of Ack1 Kinase Activation, Eranga R. Balasooriya, Deshan Madhusanka, Tania P. López-Palacios, Riley J. Eastmond, Dasun Jayatunge, Jake J. Owen, Jack S. Gashler, Christina M. Egbert, Chanaka Bulathsinghalage, Lu Liu, Stephen R. Piccolo, Joshua L. Andersen
Integrating Clinical Cancer And Ptm Proteomics Data Identifies A Mechanism Of Ack1 Kinase Activation, Eranga R. Balasooriya, Deshan Madhusanka, Tania P. López-Palacios, Riley J. Eastmond, Dasun Jayatunge, Jake J. Owen, Jack S. Gashler, Christina M. Egbert, Chanaka Bulathsinghalage, Lu Liu, Stephen R. Piccolo, Joshua L. Andersen
Faculty Publications
Beyond the most common oncogenes activated by mutation (mut-drivers), there likely exists a variety of low-frequency mut-drivers, each of which is a possible frontier for targeted therapy. To identify new and understudied mut-drivers, we developed a machine learning (ML) model that integrates curated clinical cancer data and posttranslational modification (PTM) proteomics databases. We applied the approach to 62,746 patient cancers spanning 84 cancer types and predicted 3,964 oncogenic mutations across 1,148 genes, many of which disrupt PTMs of known and unknown function. The list of putative mut-drivers includes established drivers and others with poorly understood roles in cancer. This ML …
Evaluating A Large Language Model’S Ability To Solve Programming Exercises From An Introductory Bioinformatics Course, Stephen R. Piccolo, Paul Denny, Andrew Luxton-Reilly, Samuel H. Payne, Perry G. Ridge
Evaluating A Large Language Model’S Ability To Solve Programming Exercises From An Introductory Bioinformatics Course, Stephen R. Piccolo, Paul Denny, Andrew Luxton-Reilly, Samuel H. Payne, Perry G. Ridge
Faculty Publications
Life scientists frequently write computer code when doing research. Computer programming can aid researchers in performing tasks that are not supported by existing tools. Programming can also help researchers to implement analytical logic in a way that documents their steps and thus enables others to repeat those steps. Many educational resources are available to teach computer programming, but this skill remains challenging for many researchers and students to master. Artificial-intelligence tools like OpenAI’s ChatGPT are able to interpret human-language requests to generate code. Accordingly, we evaluated the extent to which this technology might be used to perform programming tasks described …
Video Based Estimation Of Surface Currents In A Tidal Inlet, Benjamin Middour, George Voulgaris, Douglas Cahl
Video Based Estimation Of Surface Currents In A Tidal Inlet, Benjamin Middour, George Voulgaris, Douglas Cahl
Faculty Publications
Oceanic surface currents are estimated from analysis of short duration video obtained by a nadir facing camera installed on a bridge over a tidal inlet. Data analyzed consisted of 13 two-minute video clips captured approximately every 40 min over a period of 8 hr, covering a significant portion of the tidal cycle. Surface current speed and direction estimates are obtained from each collected video using (i) a method originally developed for analysis of imagery from drones (CopterCurrents) and (ii) a particle tracking method. The horizontal (u, v) surface current velocity components and total horizontal velocity magnitude, obtained from the two …
Examining Cancer Patients' Perceptions Of The Impact Of Covid-19 On Teleoncology: Findings From 15 Nigerian Outpatient Cancer Clinics, Adedayo Joseph, Abdul R. Shour, Nwamaka N. Lasebikan, Mutiu A. Jimoh, Bolanle C. Adegboyega, Emmanuella Nwachukwu, Opeyemi Awofeso, Azeezat Ajose, Abiola Ibraheem, Omolara Aminat Fatiregun, Musa Ali-Gombe, Usman M. Aliyu, Abdallah Elsaid Kotkat, Olusegun Abayomi Biyi-Olutunde, Evaristus Oseiwe Oboh, Ismail H. Zubairu, Mohammad Rifat Haider, Bankole Olatosi Ph.D., David Puthoff, Adedayo A. Onitilo
Examining Cancer Patients' Perceptions Of The Impact Of Covid-19 On Teleoncology: Findings From 15 Nigerian Outpatient Cancer Clinics, Adedayo Joseph, Abdul R. Shour, Nwamaka N. Lasebikan, Mutiu A. Jimoh, Bolanle C. Adegboyega, Emmanuella Nwachukwu, Opeyemi Awofeso, Azeezat Ajose, Abiola Ibraheem, Omolara Aminat Fatiregun, Musa Ali-Gombe, Usman M. Aliyu, Abdallah Elsaid Kotkat, Olusegun Abayomi Biyi-Olutunde, Evaristus Oseiwe Oboh, Ismail H. Zubairu, Mohammad Rifat Haider, Bankole Olatosi Ph.D., David Puthoff, Adedayo A. Onitilo
Faculty Publications
Purpose
To examine cancer patients' perspectives on the impact of COVID-19 on teleoncology in Nigeria.
Methods
Data from a multicenter survey conducted at 15 outpatient clinics to 1,097 patients with cancer from April and July 2020 were analyzed. The study outcome was telemedicine, defined as patients who reported their routine follow-up visits were converted to virtual visits because of COVID-19 (coded yes/no). Covariates included patient age, ethnicity, marital status, income, cancer treatment, service disruption, and cancer diagnosis/type. Stata/SE.v.17 (StataCorp, College Station, TX) was used to perform chi-square and logistic regression analyses. P values ≤ .05 were considered statistically significant.
Results …
Streamlining The Detection Of Human Thyroid Receptor Ligand Interactions With Xl1-Blue Cell-Free Protein Synthesis And Beta-Galactosidase Fusion Protein Biosensors, J. Porter Hunt, Tyler J. Free, Jackelyn Galiardi, Kevin M. Watt, David W. Wood, Bradley Charles Bundy
Streamlining The Detection Of Human Thyroid Receptor Ligand Interactions With Xl1-Blue Cell-Free Protein Synthesis And Beta-Galactosidase Fusion Protein Biosensors, J. Porter Hunt, Tyler J. Free, Jackelyn Galiardi, Kevin M. Watt, David W. Wood, Bradley Charles Bundy
Faculty Publications
Thyroid receptor signaling controls major physiological processes and disrupted signaling can cause severe disorders that negatively impact human life. Consequently, methods to detect thyroid receptor ligands are of great toxicologic and pharmacologic importance. Previously, we reported thyroid receptor ligand detection with cell-free protein synthesis of a chimeric fusion protein composed of the human thyroid receptor beta (hTRβ) receptor activator and a β-lactamase reporter. Here, we report a 60% reduction in sensing cost by reengineering the chimeric fusion protein biosensor to include a reporter system composed of either the full-length beta galactosidase (β-gal), the alpha fragment of β-gal (β-gal-α), or a …
Learning Experience Design As An Orienting Guide For Practice: Insights From Designing For Expertise, Jason K. Mcdonald, Tyler J. Westerberg
Learning Experience Design As An Orienting Guide For Practice: Insights From Designing For Expertise, Jason K. Mcdonald, Tyler J. Westerberg
Faculty Publications
In this paper we consider how learning experience design (LXD) improves designers’ capacities to influence learning. We do this by exploring what LXD offers the design of learning environments that help develop learners’ expertise. We discuss how LXD (a) attunes designers to different learning affordances than are emphasized in traditional ID; (b) challenges the universal applicability of common ID techniques; and (c) expands designers’ views of the outcomes for which they can design. These insights suggest that LXD is useful because it refocuses and reframes designers' work around flexible design approaches that are often deemphasized in traditional ID.
What's All The Fuss About Pickleball? Motivational Profiles Of Middle Age And Older Adult Recreational Pickleball Players, David C. Barney, Zack E. Beddoes, Keven A. Prusak, Brandon Weekes
What's All The Fuss About Pickleball? Motivational Profiles Of Middle Age And Older Adult Recreational Pickleball Players, David C. Barney, Zack E. Beddoes, Keven A. Prusak, Brandon Weekes
Faculty Publications
As a person becomes older their physical activity options may change or be reduced. One activity that is proving differently among older adults is pickleball. As of 2022 over 3.1 million people in the United States participate in pickleball (USAPA Pickleball, 2022). From the casual observer, many recreational tennis courts have been modified to accommodate the increase of pickleball players. Also, many of these pickleball players are older (40 +). Thus, the purpose of this study was to investigate the motivational profiles of 40 and older adults towards playing pickleball. Generally, it was learned that 40 and older adults participate …
Improving Behavior In An Alternative High School Summer Program Using Class‑Wide Function‑Related Intervention Teams: A Pilot Study, Paul Caldarella, Erika J. Richards, Leslie Williams, Emily J. Warburton
Improving Behavior In An Alternative High School Summer Program Using Class‑Wide Function‑Related Intervention Teams: A Pilot Study, Paul Caldarella, Erika J. Richards, Leslie Williams, Emily J. Warburton
Faculty Publications
Effective interventions are needed to help alternative high school teachers manage challenging student behaviors. One such intervention, class-wide function-related intervention teams (CWFIT), is a classroom management program based on positive behavior interventions and supports principles. CW-FIT involves teaching appropriate classroom behavioral expectations (social skills), using high behavior-specific praise-to-reprimand ratios, and an interdependent group contingency to provide differential reinforcement of appropriate classroom behavior and eliminate potential reinforcement of problem behavior. In this pilot study, four alternative high school teachers implemented CW-FIT during a summer school program. A series of single subject A-B designs were used over a 3-week period. Results supported …
A Probabilistic View Of Protein Stability, Conformational Specificity, And Design, Jacob A. Stern, Tyler J. Free, Kimberlee L. Stern, Spencer Gardiner, Nicholas A. Dalley, Bradley Charles Bundy, Joshua L. Price, David Wingate, Dnnis Della Corte
A Probabilistic View Of Protein Stability, Conformational Specificity, And Design, Jacob A. Stern, Tyler J. Free, Kimberlee L. Stern, Spencer Gardiner, Nicholas A. Dalley, Bradley Charles Bundy, Joshua L. Price, David Wingate, Dnnis Della Corte
Faculty Publications
Various approaches have used neural networks as probabilistic models for the design of protein sequences. These "inverse folding" models employ different objective functions, which come with trade-offs that have not been assessed in detail before. This study introduces probabilistic definitions of protein stability and conformational specificity and demonstrates the relationship between these chemical properties and the p(stucture|seq) Boltzmann probability objective. This links the Boltzmann probability objective function to experimentally verifiable outcomes. We propose a novel sequence decoding algorithm, referred to as “BayesDesign”, that leverages Bayes’ Rule to maximize the p(stucture|seq) objective instead of the p(seq|structure) objective common in inverse folding …
Precision E- Beam Polarimetry At An E-E+ B Factory Using Tau-Pair Events, J. P. Lees, V. Poireau, V, Tisserand, E. Grauges, A. Palano, G. Eigen, D. N. Brown, Yu. G. Kolomensky, M. Fritsch, H. Koch, R. Cheaib, C. Hearty, T. S. Mattison, J. A. Mckenna, R. Y. So, V. E. Blinov, A. R. Buzykaev, V. P. Druzhinin, Milind Purohit, Et. Al.
Precision E- Beam Polarimetry At An E-E+ B Factory Using Tau-Pair Events, J. P. Lees, V. Poireau, V, Tisserand, E. Grauges, A. Palano, G. Eigen, D. N. Brown, Yu. G. Kolomensky, M. Fritsch, H. Koch, R. Cheaib, C. Hearty, T. S. Mattison, J. A. Mckenna, R. Y. So, V. E. Blinov, A. R. Buzykaev, V. P. Druzhinin, Milind Purohit, Et. Al.
Faculty Publications
We present a new technique, “tau polarimetry,” for measuring the longitudinal beam polarization present in an e+e− collider through the analysis of e+e− → τ+τ− events. By exploiting the sensitivity of τ decay kinematics to the longitudinal polarization of the beams, we demonstrate that the longitudinal polarization can be measured with a 3 per mil systematic uncertainty at the interaction point using a technique that is independent of spin and beam transport modeling. Using 424.2 ± 1.8 fb−1 of BABAR data at √ s = 10.58 GeV, the average longitudinal …
Recent Breakthroughs In Using Quantum Dots For Cancer Imaging And Drug Delivery Purposes, Aisha Hamidu, William G. Pitt, Ghaleb A. Husseini
Recent Breakthroughs In Using Quantum Dots For Cancer Imaging And Drug Delivery Purposes, Aisha Hamidu, William G. Pitt, Ghaleb A. Husseini
Faculty Publications
Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly investigate tumor cells at a cellular level in contrast to prior diagnostic techniques. Quantum dots (QDs) are functional nanoparticles reported to be useful for diagnosis. QDs are semiconducting tiny nanocrystals, 2–10 nm in diameter, with exceptional and useful optoelectronic properties that can be tailored to sensitively report on their environment. This review highlights these exceptional semiconducting QDs and their properties and synthesis methods when used …