Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Law (3974)
- Physical Sciences and Mathematics (1869)
- Social and Behavioral Sciences (1417)
- Engineering (1179)
- Arts and Humanities (1044)
-
- Life Sciences (781)
- Business (729)
- Medicine and Health Sciences (680)
- Physics (674)
- Religion (618)
- Constitutional Law (427)
- Education (420)
- Astrophysics and Astronomy (352)
- Computer Sciences (347)
- Chemical Engineering (327)
- Public Health (309)
- Psychology (305)
- Biblical Studies (268)
- Mechanical Engineering (240)
- Chemistry (235)
- Electrical and Computer Engineering (233)
- Courts (228)
- Biology (227)
- Criminal Law (223)
- Linguistics (204)
- Accounting (197)
- Library and Information Science (197)
- Civil Rights and Discrimination (172)
- Finance and Financial Management (168)
- Criminal Procedure (153)
- Institution
-
- Louisiana State University (4905)
- Brigham Young University (2395)
- University of South Carolina (1827)
- William & Mary Law School (1179)
- Andrews University (749)
-
- San Jose State University (630)
- The University of Southern Mississippi (600)
- University of Missouri School of Law (582)
- Santa Clara Law (439)
- Air Force Institute of Technology (373)
- University of North Carolina School of Law (370)
- Case Western Reserve University School of Law (367)
- University of New Hampshire (312)
- Stephen F. Austin State University (238)
- Marquette University Law School (220)
- St. John's University School of Law (217)
- Florida International University College of Law (202)
- University of South Dakota (194)
- Villanova University Charles Widger School of Law (136)
- University of Northern Iowa (126)
- Luther Seminary (113)
- Rollins College (73)
- Hope College (69)
- Linfield University (57)
- University of Maine School of Law (55)
- East Texas A&M University (54)
- Fordham University (50)
- Texas Southern University (49)
- Denison University (48)
- University of Southern Maine (36)
- Keyword
-
- Law (112)
- Constitutional Law (110)
- Machine learning (88)
- Religion (77)
- Evidence (71)
-
- Chemistry (69)
- Chemical Engineering (66)
- Children (65)
- Litigation (63)
- Taxation (61)
- Courts (60)
- Devins works (60)
- Accretion (59)
- Education (59)
- Refereed Publications (59)
- United States Supreme Court (57)
- Biblical Studies (56)
- Discrimination (56)
- Physics (56)
- Public Health (54)
- United States (54)
- Contracts (51)
- Theology (51)
- Climate change (50)
- Book review (49)
- Binaries: close (48)
- Church History (47)
- Artificial intelligence (46)
- Federal Courts (46)
- Remote sensing (46)
- Publication Year
- File Type
Articles 1081 - 1110 of 16755
Full-Text Articles in Entire DC Network
Erratum: Correction To: Environment And Host Genetics Influence The Biogeography Of Plant Microbiome Structure (Microbial Ecology (2023) 86 4 (2858-2868)), Na Wei, Jiaqi Tan
Erratum: Correction To: Environment And Host Genetics Influence The Biogeography Of Plant Microbiome Structure (Microbial Ecology (2023) 86 4 (2858-2868)), Na Wei, Jiaqi Tan
Faculty Publications
No abstract provided.
The Superfluous Rules Of Evidence, Jeffrey Bellin
The Superfluous Rules Of Evidence, Jeffrey Bellin
Faculty Publications
There are few American legal codifications as successful as the Federal Rules of Evidence. But this success masks the project’s uncertain beginnings. The drafters of the Federal Rules worried that lawmakers would not adopt the new rules and that judges would not follow them. As a result, they included at least thirty rules of evidence that do not, in fact, alter the admissibility of evidence. Instead, these rules: (1) market the rules project, and (2) guide judges away from anticipated errors in applying the (other) nonsuperfluous rules.
Given the superfluous rules’ covert mission, it should not be surprising that the …
Second Amendment Exceptionalism: Public Expression And Public Carry, Timothy Zick
Second Amendment Exceptionalism: Public Expression And Public Carry, Timothy Zick
Faculty Publications
In New York State Rifle & Pistol Ass’n v. Bruen, the Supreme Court recognized a right to carry firearms in public places. The scope of that right will depend on where, why, and how governments regulated public carry during the eighteenth and perhaps nineteenth centuries. The Court claimed that its turn to history for determining the scope of Second Amendment rights “accords with” and “comports with” how the Court has interpreted First Amendment rights. This Article examines and rejects that claim, both in general and specifically as it applies to the public exercise of Second Amendment rights. Although Bruen …
The Chatgpt Artificial Intelligence Chatbot: How Well Does It Answer Accounting Assessment Questions?, David A. Wood, Ryan D. Sommerfeldt, Muskan P. Achhpilia, Mollie T. Adams, Sanaz Aghazadeh, William G. Heninger, Jeffrey Pickerd, Jon Kerr
The Chatgpt Artificial Intelligence Chatbot: How Well Does It Answer Accounting Assessment Questions?, David A. Wood, Ryan D. Sommerfeldt, Muskan P. Achhpilia, Mollie T. Adams, Sanaz Aghazadeh, William G. Heninger, Jeffrey Pickerd, Jon Kerr
Faculty Publications
ChatGPT, a language-learning model chatbot, has garnered considerable attention for its ability to respond to users’ questions. Using data from 14 countries and 186 institutions, we compare ChatGPT and student performance for 28,085 questions from accounting assessments and textbook test banks. As of January 2023, ChatGPT provides correct answers for 56.5 percent of questions and partially correct answers for an additional 9.4 percent of questions. When considering point values for questions, students significantly outperform ChatGPT with a 76.7 percent average on assessments compared to 47.5 percent for ChatGPT if no partial credit is awarded and 56.5 percent if partial credit …
Relations Among Bitcoin Futures, Bitcoin Spot, Investor Attention, And Sentiment, Arun Narayanasamy, Humnath Panta, Rohit Agarwal
Relations Among Bitcoin Futures, Bitcoin Spot, Investor Attention, And Sentiment, Arun Narayanasamy, Humnath Panta, Rohit Agarwal
Faculty Publications
This research investigates the function of price discovery between the Bitcoin futures and the spot markets while also analyzing the impact of investor sentiment and attention on these markets. This study utilizes various statistical models to examine the short-term and long-term relations between these variables, including the bivariate Granger causality model, the ARDL and NARDL models, and the Johansen cointegration procedure with a vector error correction mechanism. The results suggest that there is no statistical evidence of price discovery between the Bitcoin spot price and futures, and the term structure of the Bitcoin futures neither enriches nor impairs this lead …
On The Trajectory Of Discrimination: A Meta-Analysis And Forecasting Survey Capturing 44 Years Of Field Experiments On Gender And Hiring Decisions, Helen C. Harton, Michael Schaerer, Christilene Du Plessis, My Hoang Bao Nguyen, Robbie C.M.Van Aert, Leo Tiokhin, Daniel Lakens, Elena Giulia Clemente, Thomas Pfeiffer, Anna Dreber, Magnus Johannesson, Cory J. Clark, Eric Luis Uhlmann
On The Trajectory Of Discrimination: A Meta-Analysis And Forecasting Survey Capturing 44 Years Of Field Experiments On Gender And Hiring Decisions, Helen C. Harton, Michael Schaerer, Christilene Du Plessis, My Hoang Bao Nguyen, Robbie C.M.Van Aert, Leo Tiokhin, Daniel Lakens, Elena Giulia Clemente, Thomas Pfeiffer, Anna Dreber, Magnus Johannesson, Cory J. Clark, Eric Luis Uhlmann
Faculty Publications
A preregistered meta-analysis, including 244 effect sizes from 85 field audits and 361,645 individual job applications, tested for gender bias in hiring practices in female-stereotypical and gender-balanced as well as male-stereotypical jobs from 1976 to 2020. A “red team” of independent experts was recruited to increase the rigor and robustness of our meta-analytic approach. A forecasting survey further examined whether laypeople (n = 499 nationally representative adults) and scientists (n = 312) could predict the results. Forecasters correctly anticipated reductions in discrimination against female candidates over time. However, both scientists and laypeople overestimated the continuation of bias against female candidates. …
Technology Specificity And Equitable Access To Pharmaceuticals, Ana Santos Rutschman
Technology Specificity And Equitable Access To Pharmaceuticals, Ana Santos Rutschman
Faculty Publications
Current models of production of pharmaceuticals, particularly those dependent on intellectual property (and adjacent) protections, often contribute to the highly asymmetrical and inequitable distribution of resulting outputs. These problems are especially acute when emerging pathogens cause transnational public health crises in which there is concurrent demand for the same medicines in both lower- and higher-income countries, with populations in the Global South getting very limited timely access, if any, to preventatives and life-saving medicines—even when an outbreak disproportionately affects populations in these very countries.
This essay examines an under-theorized and under-explored way to help correct this historical and persisting deficit …
Who Are You? Adventist Identity And The Presence Of God, John C. Peckham
Who Are You? Adventist Identity And The Presence Of God, John C. Peckham
Faculty Publications
No abstract provided.
Does Grazing Winter Cereal Rye In Iowa, Usa, Make It Profitable?, A. Plastina, J. Acharya, F. M. Marcos, M. R. Parvej, M. A. Licht, A. E. Robertson
Does Grazing Winter Cereal Rye In Iowa, Usa, Make It Profitable?, A. Plastina, J. Acharya, F. M. Marcos, M. R. Parvej, M. A. Licht, A. E. Robertson
Faculty Publications
Unproven economic returns at the farm level are a major barrier to large-scale adoption of cover crops. The objective of this study was to evaluate the short-run private net returns to producers implementing a cereal rye (Secale cereale L.) cover crop preceding the no-till corn (Zea mays L.) phase of a US Midwest corn-soybean (Glycine max [L.] Merr.) rotation in an integrated crop and cow-calf operation. We used experimental agronomic data from six location-years in Iowa to estimate private net returns to cereal rye across alternative scenarios in a partial budget framework. Net returns in the absence of grazing averaged …
Augmenting External Surface Pressures’ Predictions On Isolated Low-Rise Buildings Using Cfd Simulations, Md Faiaz Khaled, Aly Mousaad Aly
Augmenting External Surface Pressures’ Predictions On Isolated Low-Rise Buildings Using Cfd Simulations, Md Faiaz Khaled, Aly Mousaad Aly
Faculty Publications
The aim of this paper is to enhance the accuracy of predicting time-averaged external surface pressures on low-rise buildings by utilizing Computational Fluid Dynamics (CFD) simulations. To achieve this, benchmark studies of the Silsoe cube and the Texas Tech University (TTU) experimental building are employed for comparison with simulation results. The paper is structured into three main sections. In the initial part, an appropriate domain size is selected based on the precision of mean pressure coefficients on the windward face of the cube, utilizing Reynolds Averaged Navier-Stokes (RANS) turbulence models. Subsequently, recommendations regarding the optimal computational domain size for an …
Establishment Of A Birth-To-Education Cohort Of 1 Million Palestinian Refugees Using Electronic Medical Records And Electronic Education Records, Zeina Jamaluddine, Akihiro Seita, Ghada Ballout, Hussam Al-Fudoli, Gloria Paolucci, Shatha Albaik, Rami Ibrahim, Miho Sato, Hala Ghattas Ph.D., Oona M.R. Campbell
Establishment Of A Birth-To-Education Cohort Of 1 Million Palestinian Refugees Using Electronic Medical Records And Electronic Education Records, Zeina Jamaluddine, Akihiro Seita, Ghada Ballout, Hussam Al-Fudoli, Gloria Paolucci, Shatha Albaik, Rami Ibrahim, Miho Sato, Hala Ghattas Ph.D., Oona M.R. Campbell
Faculty Publications
Introduction
By linking datasets, electronic records can be used to build large birth-cohorts, enabling researchers to cost-effectively answer questions relevant to populations over the life-course. Currently, around 5.8 million Palestinian refugees live in five settings: Jordan, Lebanon, Syria, West Bank, and Gaza Strip. The United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) provides them with free primary health and elementary-school services. It maintains electronic records to do so.
We aimed to establish a birth cohort of Palestinian refugees born between 1st January 2010 and 31st December 2020 living in five settings by linking mother …
Active-Illumination Extension To The Priest And Meier Pbrdf, Mark F. Spencer, Milo W. Hyde Iv, Santasri R. Bose-Pillai, Michael A. Marciniak
Active-Illumination Extension To The Priest And Meier Pbrdf, Mark F. Spencer, Milo W. Hyde Iv, Santasri R. Bose-Pillai, Michael A. Marciniak
Faculty Publications
This paper develops a 3D vector solution for the scattering of partially coherent laser-beam illumination from statistically rough surfaces. Such a solution enables a rigorous comparison to the well-known Priest and Meier polarimetric bidirectional reflectance distribution function (pBRDF) [Opt Eng 41(5),988 (2002).]. Overall, the comparison shows excellent agreement for the normalized spectral density and the degree of polarization. Based on this agreement, the 3D vector solution also enables an extension to the Priest and Meier pBRDF that accounts for the effects of active illumination. In particular, the 3D vector solution enables the development of a closed-form expression for the spectral …
Law And Its Limits: Ethical Issues In Mary Shelly's Frankenstein Or, The Modern Prometheus, David S. Caudill
Law And Its Limits: Ethical Issues In Mary Shelly's Frankenstein Or, The Modern Prometheus, David S. Caudill
Faculty Publications
The law and literature movement is frequently associated with the use of literary images of law as a point of reflection upon the ethical obligations of lawyers. Mary Shelley’s Frankenstein (1818)—the story of a young scientist whose unorthodox experiments end up creating the famed “monster”—is not, at first glance, a likely candidate for that enterprise. However, Dr. Frankenstein’s ambition and ruthless pursuit of knowledge has become a contemporary image of science out of control and the need for ethical limitations on scientific progress. Consequently, the novel raises currently important issues of regulating science and technology. Given the lawyer’s ethical obligation …
Telling Stories In Noise: The Impact Of Background Noises On Spoken Language For People With Aphasia, Tyson G. Harmon, Brenna Scadden Nelson, Christopher Dromey, Kirsten Dixon Clawson
Telling Stories In Noise: The Impact Of Background Noises On Spoken Language For People With Aphasia, Tyson G. Harmon, Brenna Scadden Nelson, Christopher Dromey, Kirsten Dixon Clawson
Faculty Publications
Purpose: Determine how different background noise conditions affect the spoken language of participants with aphasia during a story retell task.
Method: Participants included 11 adults with mild to moderate aphasia and 11 age- and gender-matched controls. Participants retold stories in a silent baseline and five background noise conditions (conversation, monologue, phone call, cocktail, pink noise). Dependent measures of speech acoustics (fundamental frequency, mean intensity), speech fluency (speech rate, disfluent words), and language production (correct information units, lexical errors, lexical diversity, and cohesive utterances) were compared between groups and across conditions.
Results: Background noise resulted in higher fundamental frequency (F0 …
Physiological Arousal, Attentiveness, Emotion, And Word Retrieval In Aphasia: Effects And Relationships, Tyson G. Harmon, Angela Johnson, Vivian Ward, Shawn Nissen
Physiological Arousal, Attentiveness, Emotion, And Word Retrieval In Aphasia: Effects And Relationships, Tyson G. Harmon, Angela Johnson, Vivian Ward, Shawn Nissen
Faculty Publications
Purpose: To (a) compare physiological arousal and attentiveness during a confrontational naming task between participants with aphasia and a control group across four conditions that varied according to emotionality of presented stimuli and (b) explore relationships among physiological arousal, attentiveness, perceived arousal, and naming performance. We hypothesized that participants with aphasia would show lower levels of arousal and attentiveness than control participants and that emotional conditions would lead to increased physiological arousal and attentiveness.
Method: Eight participants with aphasia and 15 control participants completed a confrontational naming task under positive, negative, and neutral conditions and rated their perceived arousal after …
How Ubiquitous Is Entanglement In Quantum Field Theory, Ivan Agullo, Béatrice Bonga, Patricia Ribes-Metidieri, Dimitrios Kranas, Sergi Nadal-Gisbert
How Ubiquitous Is Entanglement In Quantum Field Theory, Ivan Agullo, Béatrice Bonga, Patricia Ribes-Metidieri, Dimitrios Kranas, Sergi Nadal-Gisbert
Faculty Publications
It is well known that entanglement is widespread in quantum field theory, in the following sense: every Reeh-Schlieder state contains entanglement between any two spatially separated regions. This applies, in particular, to the vacuum of a noninteracting scalar theory in Minkowski spacetime. Discussions on entanglement in field theory have focused mainly on subsystems containing infinitely many degrees of freedom - typically, the field modes that are supported within a compact region of space. In this article, we study entanglement in subsystems made of finitely many field degrees of freedom, in a free scalar theory in D+1-dimensional Minkowski spacetime. The focus …
Neutronic Analysis Of The Byu Molten Salt Micro Reactor, Collin Bradford, Edward Mercado, Braden Clayton, Lagrande Gunnell, Andrew Larsen, Matthew Memmott
Neutronic Analysis Of The Byu Molten Salt Micro Reactor, Collin Bradford, Edward Mercado, Braden Clayton, Lagrande Gunnell, Andrew Larsen, Matthew Memmott
Faculty Publications
Background: With the rising need for reliable and clean energy, researchers at Brigham Young University created a molten salt microreactor (MSMR) concept to help meet the world’s growing energy demands. The MSMR is rated at 45 MWth and is uniquely capable of passively dissipating all decay heat using conduction only.
Methods: This work presents the results of the simulated neutronic behavior of the MSMR using the Monte Carlo neutronics code OpenMC with the ENDF/B-VII.1 cross-section library at steady state conditions. The specific characteristics discussed in this work are: keff, power profile, axial and radial peak power factors, Doppler coefficient of …
Chemical Communication In Insects: New Advances In Integrated Pest Management Strategies, Angel Guerrero, Gadi V.P. Reddy
Chemical Communication In Insects: New Advances In Integrated Pest Management Strategies, Angel Guerrero, Gadi V.P. Reddy
Faculty Publications
No abstract provided.
Relational Sanctification, Communal Coping, And Depression Among African American Couples, Antonius D. Skipper, Andrew H. Rose, Noel A. Card, Travis James Moore, Debra Lavender-Bratcher, Cassandra Chaney
Relational Sanctification, Communal Coping, And Depression Among African American Couples, Antonius D. Skipper, Andrew H. Rose, Noel A. Card, Travis James Moore, Debra Lavender-Bratcher, Cassandra Chaney
Faculty Publications
Despite the common use of religious buffers, African Americans are disproportionately affected by depressive symptoms. Communal coping may serve as one factor in helping religious African American couples alleviate the symptoms of depression. This study examines the association between relational sanctification and depressive symptoms as mediated by the communal coping of 467 African American married and cohabiting couples. Data from the sampled couples were analyzed using a common fate model, and analyses revealed higher scores on the measure of sanctification were associated with more communal coping; more communal coping was associated with fewer depressive symptoms among women and men, and …
Reevaluation Of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin Equivalency Factors For Dioxin-Like Polychlorinated Dibenzo-P-Dioxins, Polychlorinated Dibenzofurans, And Polychlorinated Biphenyls For Fishes, Jon A. Doering, Donald E. Tillitt, Steve Wiseman
Reevaluation Of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin Equivalency Factors For Dioxin-Like Polychlorinated Dibenzo-P-Dioxins, Polychlorinated Dibenzofurans, And Polychlorinated Biphenyls For Fishes, Jon A. Doering, Donald E. Tillitt, Steve Wiseman
Faculty Publications
An expert meeting was organized by the World Health Organization (WHO) in 1997 to streamline assessments of risk posed by mixtures of dioxin-like chemicals (DLCs) through development of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) equivalency factors (TEFs) for mammals, birds, and fishes. No reevaluation has been performed for fish TEFs. Therefore, the objective of the present study was to reevaluate the TEFs for fishes based on an updated database of relative potencies (RePs) for DLCs. Selection criteria consistent with the WHO meeting resulted in 53 RePs across 14 species of fish ultimately being considered. Of these RePs, 70% were not available at the time …
Sexually Dimorphic Oxytocin Receptor-Expressing (Oxtr) Neurons In The Anteroventral Periventricular Nucleus (Avpv) In The Postpartum Female Mouse Are Involved In Maternal Behavior, Kaustubh Sharma, Armita A. Govar, Bandana Ghimire, Katsuhiko Nishimori, Elizabeth Hammock, Ryoichi Teruyama
Sexually Dimorphic Oxytocin Receptor-Expressing (Oxtr) Neurons In The Anteroventral Periventricular Nucleus (Avpv) In The Postpartum Female Mouse Are Involved In Maternal Behavior, Kaustubh Sharma, Armita A. Govar, Bandana Ghimire, Katsuhiko Nishimori, Elizabeth Hammock, Ryoichi Teruyama
Faculty Publications
Maternal care is crucial for the survival and development of offspring. Oxytocin modulates maternal behavior by binding to oxytocin receptors (OXTRs) in various parts of the brain. Previously, we showed that OXTRs are expressed in the anteroventral periventricular nucleus (AVPV) of female, but not male mice. Because the AVPV is involved in the regulation of maternal behavior and oxytocin enhances its induction, this finding leads to the hypothesis that the female specific population of OXTR neurons in the AVPV regulates maternal behavior. To address this hypothesis, OXTR-Venus reporter mice were used to assess if expression levels of OXTR in the …
Pubertal Progression And Its Relationship To Psychological And Behavioral Outcomes Among Adolescent Boys, Meng-Che Tsai, Yu-Chung Lawrence Wang, Hsun-Yu Chan
Pubertal Progression And Its Relationship To Psychological And Behavioral Outcomes Among Adolescent Boys, Meng-Che Tsai, Yu-Chung Lawrence Wang, Hsun-Yu Chan
Faculty Publications
Variations in pubertal timing and tempo have relevance to psychosocial development. Accounting for pubertal timing, tempo, and psychosocial development simultaneously in a model remains challenging. This study aimed to document the typology of pubertal development in a cohort of Taiwanese adolescent boys and then to examine how the associations between psychosocial variables across time vary by the patterns of pubertal development. A group of adolescent boys (n = 1,368) reported pubertal signs and psychosocial variables for 3 years since seventh grade. The growth mixture model revealed three major classes of pubertal transition: average pubertal growth, late-onset with rapid catch-up, and …
Machine-Learning-Based Thermal Conductivity Prediction For Additively Manufactured Alloys, Uttam Bhandari, Yehong Chen, Huan Ding, Congyuan Zeng, Selami Emanet, Paul R. Gradl, Shengmin Guo
Machine-Learning-Based Thermal Conductivity Prediction For Additively Manufactured Alloys, Uttam Bhandari, Yehong Chen, Huan Ding, Congyuan Zeng, Selami Emanet, Paul R. Gradl, Shengmin Guo
Faculty Publications
Thermal conductivity (TC) is greatly influenced by the working temperature, microstructures, thermal processing (heat treatment) history and the composition of alloys. Due to computational costs and lengthy experimental procedures, obtaining the thermal conductivity for novel alloys, particularly parts made with additive manufacturing, is difficult and it is almost impossible to optimize the compositional space for an absolute targeted value of thermal conductivity. To address these difficulties, a machine learning method is explored to predict the TC of additive manufactured alloys. To accomplish this, an extensive thermal conductivity dataset for additively manufactured alloys was generated for several AM alloy families (nickel, …
Coupled Wellbore-Reservoir Modelling To Evaluate Co2 Injection Rate Distribution Over Thick Multilayer Storage Zones, Mohamed Abdelaal, Mehdi Zeidouni
Coupled Wellbore-Reservoir Modelling To Evaluate Co2 Injection Rate Distribution Over Thick Multilayer Storage Zones, Mohamed Abdelaal, Mehdi Zeidouni
Faculty Publications
Technical and economic feasibility of Geologic CO2 Storage (GCS) projects requires maximizing the amount of stored CO2 per unit pore space of the storage zone per well. Considering injection through a fully penetrating vertical well in a multi-layer thick aquifer, CO2 would be unevenly distributed over the aquifer thickness, underutilizing the available pore space. In this work, we use coupled wellbore-reservoir modelling to investigate the interplay between the parameters that control CO2 pore-space filling. Flow capacity profile and gravity/buoyancy override are the primary factors controlling CO2 flux into a layered system. In addition, a higher fraction of CO2 would flow …
Integrating Clinical Cancer And Ptm Proteomics Data Identifies A Mechanism Of Ack1 Kinase Activation, Eranga R. Balasooriya, Deshan Madhusanka, Tania P. López-Palacios, Riley J. Eastmond, Dasun Jayatunge, Jake J. Owen, Jack S. Gashler, Christina M. Egbert, Chanaka Bulathsinghalage, Lu Liu, Stephen R. Piccolo, Joshua L. Andersen
Integrating Clinical Cancer And Ptm Proteomics Data Identifies A Mechanism Of Ack1 Kinase Activation, Eranga R. Balasooriya, Deshan Madhusanka, Tania P. López-Palacios, Riley J. Eastmond, Dasun Jayatunge, Jake J. Owen, Jack S. Gashler, Christina M. Egbert, Chanaka Bulathsinghalage, Lu Liu, Stephen R. Piccolo, Joshua L. Andersen
Faculty Publications
Beyond the most common oncogenes activated by mutation (mut-drivers), there likely exists a variety of low-frequency mut-drivers, each of which is a possible frontier for targeted therapy. To identify new and understudied mut-drivers, we developed a machine learning (ML) model that integrates curated clinical cancer data and posttranslational modification (PTM) proteomics databases. We applied the approach to 62,746 patient cancers spanning 84 cancer types and predicted 3,964 oncogenic mutations across 1,148 genes, many of which disrupt PTMs of known and unknown function. The list of putative mut-drivers includes established drivers and others with poorly understood roles in cancer. This ML …
Friction-In-Design Regulation As 21st Century Time, Place, And Manner Restriction, Brett Frischmann, Susan Benesch
Friction-In-Design Regulation As 21st Century Time, Place, And Manner Restriction, Brett Frischmann, Susan Benesch
Faculty Publications
Digital networked society needs friction-in-design regulation that targets the digital architectures, supposedly smart (data-driven, algorithmic) systems, and interfaces that shape human interactions, behavior, and will (beliefs, preferences, values, intentions). The relentless push to eliminate friction for the sake of efficiency has hidden social costs that affect basic human capabilities and society. A general course correction is needed.
Friction in the digital networked environment can come in many forms. It can be as simple as a time delay prior to publishing a social media post, a notice that provides salient information coupled with a nudge toward actual deliberation, or a query …
Conservative Estimation Of Inertial Sensor Errors Using Allan Variance Data, Kyle A. Lethander, Clark N. Taylor
Conservative Estimation Of Inertial Sensor Errors Using Allan Variance Data, Kyle A. Lethander, Clark N. Taylor
Faculty Publications
To understand the error sources present in inertial sensors, both the white (time-invariant) and correlated noise sources must be properly characterized. To understand both sources, the standard approach (IEEE standards 647-2006, 952-2020) is to compute the Allan variance of the noise and then use human-based interpretation of linear trends to estimate the separate noise sources present in a sensor. Recent work has sought to overcome the graphical nature and visual-inspection basis of this approach leading to more accurate noise estimates. However, when using noise characterization in a filter, it is important that the noise estimates be not only accurate but …
Lightning Forecast From Chaotic And Incomplete Time Series Using Wavelet De-Noising And Spatiotemporal Kriging, Jared K. Nystrom, Raymond Hill, Andrew J. Geyer, Joseph J. Pignatiello Jr., Eric Chicken
Lightning Forecast From Chaotic And Incomplete Time Series Using Wavelet De-Noising And Spatiotemporal Kriging, Jared K. Nystrom, Raymond Hill, Andrew J. Geyer, Joseph J. Pignatiello Jr., Eric Chicken
Faculty Publications
Purpose: Present a method to impute missing data from a chaotic time series, in this case lightning prediction data, and then use that completed dataset to create lightning prediction forecasts.
Design/Methodology/Approach: Using the technique of spatiotemporal kriging to estimate data that is autocorrelated but in space and time. Using the estimated data in an imputation methodology completes a dataset used in lighting prediction.
Findings: The techniques provided prove robust to the chaotic nature of the data, and the resulting time series displays evidence of smoothing while also preserving the signal of interest for lightning prediction.
Abstract © Emerald Publishing …
Evaluating A Large Language Model’S Ability To Solve Programming Exercises From An Introductory Bioinformatics Course, Stephen R. Piccolo, Paul Denny, Andrew Luxton-Reilly, Samuel H. Payne, Perry G. Ridge
Evaluating A Large Language Model’S Ability To Solve Programming Exercises From An Introductory Bioinformatics Course, Stephen R. Piccolo, Paul Denny, Andrew Luxton-Reilly, Samuel H. Payne, Perry G. Ridge
Faculty Publications
Life scientists frequently write computer code when doing research. Computer programming can aid researchers in performing tasks that are not supported by existing tools. Programming can also help researchers to implement analytical logic in a way that documents their steps and thus enables others to repeat those steps. Many educational resources are available to teach computer programming, but this skill remains challenging for many researchers and students to master. Artificial-intelligence tools like OpenAI’s ChatGPT are able to interpret human-language requests to generate code. Accordingly, we evaluated the extent to which this technology might be used to perform programming tasks described …
Video Based Estimation Of Surface Currents In A Tidal Inlet, Benjamin Middour, George Voulgaris, Douglas Cahl
Video Based Estimation Of Surface Currents In A Tidal Inlet, Benjamin Middour, George Voulgaris, Douglas Cahl
Faculty Publications
Oceanic surface currents are estimated from analysis of short duration video obtained by a nadir facing camera installed on a bridge over a tidal inlet. Data analyzed consisted of 13 two-minute video clips captured approximately every 40 min over a period of 8 hr, covering a significant portion of the tidal cycle. Surface current speed and direction estimates are obtained from each collected video using (i) a method originally developed for analysis of imagery from drones (CopterCurrents) and (ii) a particle tracking method. The horizontal (u, v) surface current velocity components and total horizontal velocity magnitude, obtained from the two …