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A Cultural Models Approach To Service Recovery, Glenn L. Christensen, Gaby Odekerken-Schröder, Torsten Ringberg Jul 2007

A Cultural Models Approach To Service Recovery, Glenn L. Christensen, Gaby Odekerken-Schröder, Torsten Ringberg

Faculty Publications

Service recovery research remains conflicted in its understanding of consumers’ recovery expectations and of why similar goods or service failures may lead to different recovery expectations. The authors argue that this conflict results from the assumption that consumer recovery expectations are monolithic and largely homogeneous, driven mainly by behavioral, relational, or contextual stimuli. Instead, recovery scenarios involving high-involvement (i.e., self-relevant) goods and service failures may activate closely held, identity-related cultural models that, though ultimately applied to regain balance (a foundational schema), differ according to their sociocultural heritage and create a range of unique consumer recovery preferences. The authors empirically identify …

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Characterization Of Beaf Mutations Isolated By Homologous Recombination In Drosophila, Swarnava Roy, Matthew K. Gilbert, Craig M. Hart Jun 2007

Characterization Of Beaf Mutations Isolated By Homologous Recombination In Drosophila, Swarnava Roy, Matthew K. Gilbert, Craig M. Hart

Faculty Publications

The Drosophila BEAF-32A and BEAF-32B proteins bind to the scs′ insulator and to hundreds of other sites on Drosophila chromosomes. These two proteins are encoded by the same gene. We used ends-in homologous recombination to generate the null BEAFAB-KO allele and also isolated the BEAF A-KO allele that eliminates production of only the BEAF-32A protein. We find that the BEAF proteins together are essential, but BEAF-32B alone is sufficient to obtain viable flies. Our results show that BEAF is important for both oogenesis and development. Maternal or zygotic BEAF is sufficient to obtain adults, although having only maternal BEAF impairs …

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Molecular Phylogeny Of The Scincid Lizards Of New Caledonia And Adjacent Areas: Evidence For A Single Origin Of The Endemic Skinks Of Tasmantis, Sarah A. Smith, Ross A. Sadlier, Aaron M. Bauer, Christopher C. Austin, Todd Jackman Jun 2007

Molecular Phylogeny Of The Scincid Lizards Of New Caledonia And Adjacent Areas: Evidence For A Single Origin Of The Endemic Skinks Of Tasmantis, Sarah A. Smith, Ross A. Sadlier, Aaron M. Bauer, Christopher C. Austin, Todd Jackman

Faculty Publications

We use ∼1900 bp of mitochondrial (ND2) and nuclear (c-mos and Rag-1) DNA sequence data to recover phylogenetic relationships among 58 species and 26 genera of Eugongylus group scincid lizards from New Caledonia, Lord Howe Island, New Zealand, Australia and New Guinea. Taxon sampling for New Caledonian forms was nearly complete. We find that the endemic skink genera occurring on New Caledonia, New Zealand and Lord Howe Island, which make up the Gondwanan continental block Tasmantis, form a monophyletic group. Within this group New Zealand and New Zealand + Lord Howe Island form monophyletic clades. These clades are nested within …

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Gonadotropin-Releasing Hormone And Receptor Distributions In The Visual Processing Regions Of Four Coral Reef Fishes, Karen P. Maruska, Timothy C. Tricas Jun 2007

Gonadotropin-Releasing Hormone And Receptor Distributions In The Visual Processing Regions Of Four Coral Reef Fishes, Karen P. Maruska, Timothy C. Tricas

Faculty Publications

Gonadotropin-releasing hormone (GnRH) is widely distributed in the brain of fishes where it may function as a neuromodulator of sensory processing and behavior. Immunocytochemical and neuronal label experiments were conducted on species from four families of coral reef fishes (Chaetodontidae, butterflyfish; Pomacentridae, damselfish; Gobiidae, goby; and Labridae, wrasse) to assess conservation of GnRH targets in the visual processing retina and brain. In all species, GnRH-immunoreactive (-ir) axons from the terminal nerve project principally to the boundary between the inner plexiform (IPL) and inner nuclear (INL) layers of the retina, and are less prominent in the optic nerve, ganglion cell, IPL …

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Applications Of Chitosan For Improvement Of Quality And Shelf Life Of Foods: A Review, H. K. No, S. P. Meyers, W. Prinyawiwatkul, Z. Xu Jun 2007

Applications Of Chitosan For Improvement Of Quality And Shelf Life Of Foods: A Review, H. K. No, S. P. Meyers, W. Prinyawiwatkul, Z. Xu

Faculty Publications

Chitosan is a modified, natural biopolymer derived by deacetylation of chitin, a major component of the shells of crustacean. Recently, chitosan has received increased attention for its commercial applications in the biomedical, food, and chemical industries. Use of chitosan in food industry is readily seen due to its several distinctive biological activities and functional properties. The antimicrobial activity and film-forming property of chitosan make it a potential source of food preservative or coating material of natural origin. This review focuses on the applications of chitosan for improvement of quality and shelf life of various foods from agriculture, poultry, and seafood …

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Rnai Knockdown Of Nopp140 Induces Minute-Like Phenotypes In Drosophila, Zhengfang Cui, Patrick J. Dimario Jun 2007

Rnai Knockdown Of Nopp140 Induces Minute-Like Phenotypes In Drosophila, Zhengfang Cui, Patrick J. Dimario

Faculty Publications

Nopp140 associates with small nucleolar RNPs to chaperone pre-rRNA processing and ribosome assembly. Alternative splicing yields two isoforms in Drosophila: Nopp140-True is homologous to vertebrate Nopp140 particularly in its carboxy terminus, whereas Nopp140-RGG contains a glycine and arginine-rich (RGG) carboxy terminus typically found in vertebrate nucleolin. Loss of ribosome function or production at critical points in development leads to Minute phenotypes in Drosophila or the Treacher Collins syndrome (TCS) in humans. To ascertain the functional significance of Nopp140 in Drosophila development, we expressed interfering RNA using the GAL4/UAS system. Reverse transcription-PCR showed variable losses of Nopp140 mRNA in larvae from …

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Brainstem Cholinergic Modulation Of Muscle Tone In Infant Rats, Andrew J. Gall, Amy Poremba, Mark S. Blumberg Jun 2007

Brainstem Cholinergic Modulation Of Muscle Tone In Infant Rats, Andrew J. Gall, Amy Poremba, Mark S. Blumberg

Faculty Publications

In week-old rats, lesions of the dorsolateral pontine tegmentum (DLPT) and nucleus pontis oralis (PnO) have opposing effects on nuchal muscle tone. Specifically, pups with DLPT lesions exhibit prolonged bouts of nuchal muscle atonia (indicative of sleep) and pups with PnO lesions exhibit prolonged bouts of high nuchal muscle tone (indicative of wakefulness). Here we test the hypothesis that nuchal muscle tone is modulated, at least in part, by cholinergically mediated interactions between these two regions. First, in unanesthetized pups, we found that chemical infusion of the cholinergic agonist carbachol (22 mM, 0.1 µL) within the DLPT produced high muscle …

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Multiscale Mode Dynamics Of A Tethered Membrane, Ras B. Pandey, Kelly L. Anderson, B. L. Farmer Jun 2007

Multiscale Mode Dynamics Of A Tethered Membrane, Ras B. Pandey, Kelly L. Anderson, B. L. Farmer

Faculty Publications

Stochastic dynamics of a tethered membrane with a bond-fluctuating coarse-grained Monte Carlo simulation shows, in addition to diffusion, nondiffusive behavior sensitive to the type of membrane, its size, and quality of the solvent. Motion of the membrane’s center node is described by the variation of the mean-square displacement (R2n) with time step (t), i.e., R2n∝t2ν with the exponent ν≃1/8−1∕6 in the short time followed by subdiffusive power laws (i.e., ν∼1∕5, 1∕10) in the intermediate time regimes before reaching diffusion ν=1. The crossover between in-plane wrinkle modes is identified from the segmental (node) motion of the membrane.

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Assessment Of Labview And Multisim In The Delivery Of Electronics Laboratory Content, Julio Garcia, Patricia Backer Jun 2007

Assessment Of Labview And Multisim In The Delivery Of Electronics Laboratory Content, Julio Garcia, Patricia Backer

Faculty Publications

The goal of this study, funded by the National Science Foundation, was to adapt the work of other researchers to improve the delivery of electronics lecture and laboratory content in the Electronics & Computer Technology (ECT) area. From the extensive research on ethnic and gender differences in learning styles, the evidence suggests that ethnic minorities and women work best when the material is organized so that students work in teams and have a high level of hands-on experimentation and problem-solving. We developed our materials to maximize these aspects since in our institution the “minority” constitutes the majority of our student …

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Computational Studies Of Intramolecular Hydrogen Atom Transfers In The Ss-Hydroxyethylperoxy And Ss -Hydroxyethoxy Radicals, Keith T. Kuwata, Theodore S. Dibble, Emily Sliz, Erin B. Petersen May 2007

Computational Studies Of Intramolecular Hydrogen Atom Transfers In The Ss-Hydroxyethylperoxy And Ss -Hydroxyethoxy Radicals, Keith T. Kuwata, Theodore S. Dibble, Emily Sliz, Erin B. Petersen

Faculty Publications

"The ß-hydroxyethylperoxy (I) and ß-hydroxyethoxy (III) radicals are prototypes of species that can undergo hydrogen atom transfer across their intramolecular hydrogen bonds. These reactions may play an important role in both the atmosphere and in combustion systems. We have used density functional theory and composite electronic structure methods to predict the energetics of these reactions, RRKM/master equation simulations to model the kinetics of chemically activated I, and variational transition state theory (TST) to predict thermal rate constants for the 1,5-hydrogen shift in I (Reaction 1) and the 1,4-hydrogen shift in III (Reaction 2). Our multi-coefficient Gaussian-3 calculations predict that Reaction …

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Genome Of The Marsupial Monodelphis Domestica Reveals Innovation In Non-Coding Sequences, Tarjei S. Mikkelsen, Matthew J. Wakefield, Bronwen Aken, Chris T. Amemiya, Jean L. Chang, Shannon Duke, Manuel Garber, Andrew J. Gentles, Leo Goodstadt, Andreas Heger, Jerzy Jurka, Michael Kamal, Evan Mauceli, Stephen M.J. Searle, Ted Sharpe, Michelle L. Baker, Mark A. Batzer, Panayiotis V. Benos, Katherine Belov, Michele Clamp, April Cook, James Cuff, Radhika Das, Lance Davidow, Janine E. Deakin, Melissa J. Fazzari, Jacob L. Glass, Manfred Grabherr, John M. Greally, Wanjun Gu, Timothy A. Hore, Gavin A. Huttley, Michael Kleber, Randy L. Jirtle May 2007

Genome Of The Marsupial Monodelphis Domestica Reveals Innovation In Non-Coding Sequences, Tarjei S. Mikkelsen, Matthew J. Wakefield, Bronwen Aken, Chris T. Amemiya, Jean L. Chang, Shannon Duke, Manuel Garber, Andrew J. Gentles, Leo Goodstadt, Andreas Heger, Jerzy Jurka, Michael Kamal, Evan Mauceli, Stephen M.J. Searle, Ted Sharpe, Michelle L. Baker, Mark A. Batzer, Panayiotis V. Benos, Katherine Belov, Michele Clamp, April Cook, James Cuff, Radhika Das, Lance Davidow, Janine E. Deakin, Melissa J. Fazzari, Jacob L. Glass, Manfred Grabherr, John M. Greally, Wanjun Gu, Timothy A. Hore, Gavin A. Huttley, Michael Kleber, Randy L. Jirtle

Faculty Publications

We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis domestica). As the first metatherian ('marsupial') species to be sequenced, the opossum provides a unique perspective on the organization and evolution of mammalian genomes. Distinctive features of the opossum chromosomes provide support for recent theories about genome evolution and function, including a strong influence of biased gene conversion on nucleotide sequence composition, and a relationship between chromosomal characteristics and X chromosome inactivation. Comparison of opossum and eutherian genomes also reveals a sharp difference in evolutionary innovation between protein-coding and non-coding functional elements. True innovation in …

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Disambiguation Of Overlapping Experiences By Neurons In The Medial Entorhinal Cortex., Lipton Pa, White Ja, Eichenbaum H May 2007

Disambiguation Of Overlapping Experiences By Neurons In The Medial Entorhinal Cortex., Lipton Pa, White Ja, Eichenbaum H

Faculty Publications

No abstract provided.

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Retroposition And Evolution Of The Dna-Binding Motifs Of Yy1, Yy2 And Rex1, Jeong Do Kim, Christopher Faulk, Joomyeong Kim May 2007

Retroposition And Evolution Of The Dna-Binding Motifs Of Yy1, Yy2 And Rex1, Jeong Do Kim, Christopher Faulk, Joomyeong Kim

Faculty Publications

YY1 is a DNA-binding transcription factor found in both vertebrates and invertebrates. Database searches identified 62 YY1 related sequences from all the available genome sequences ranging from flying insects to human. These sequences are characterized by high levels of sequence conservation, ranging from 66% to 100% similarity, in the zinc finger DNA-binding domain of the predicted proteins. Phylogenetic analyses uncovered duplication events of YY1 in several different lineages, including flies, fish and mammals. Retroposition is responsible for generating one duplicate in flies, PHOL from PHO, and two duplicates in placental mammals, YY2 and Reduced Expression 1 (REX1) from YY1. DNA-binding …

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Caspase Activity During Cell Stasis: Avoidance Of Apoptosis In An Invertebrate Extremophile, Artemia Franciscana, Michael A. Menze, Steven C. Hand May 2007

Caspase Activity During Cell Stasis: Avoidance Of Apoptosis In An Invertebrate Extremophile, Artemia Franciscana, Michael A. Menze, Steven C. Hand

Faculty Publications

Evaluation of apoptotic processes downstream of the mitochondrion reveals caspase-9- and low levels of caspase-3-like activities in partly purified extracts of Artemia franciscana embryos. However, in contrast to experiments with extracts of human hepatoma cells, cytochrome c fails to activate caspase-3 or -9 in extracts from A. franciscana. Furthermore, caspase-9 activity is sensitive to exogenous calcium. The addition of 5 mM calcium leads to a 4.86 ± 0.19 fold (SD) (n = 3) increase in activity, which is fully prevented with 150 mM KCl. As with mammalian systems, high ATP (>1.25 mM) suppresses caspase activity in A. franciscana extracts. …

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Relationships Among Ecologically Important Dimensions Of Plant Trait Variation In Seven Neotropical Forests, Ian J. Wright, David D. Ackerly, Frans Bongers, Kyle E. Harms, Guillermo Ibarra-Manriquez, Miguel Martinez-Ramos, Susan J. Mazer, Helene C. Muller-Landau, Horacio Paz, Nigel C.A. Pitman, Lourens Poorter, Miles R. Silman, Corine F. Vriesendorp, Cam O. Webb, Mark Westoby, S. Joseph Wright May 2007

Relationships Among Ecologically Important Dimensions Of Plant Trait Variation In Seven Neotropical Forests, Ian J. Wright, David D. Ackerly, Frans Bongers, Kyle E. Harms, Guillermo Ibarra-Manriquez, Miguel Martinez-Ramos, Susan J. Mazer, Helene C. Muller-Landau, Horacio Paz, Nigel C.A. Pitman, Lourens Poorter, Miles R. Silman, Corine F. Vriesendorp, Cam O. Webb, Mark Westoby, S. Joseph Wright

Faculty Publications

• Background and Aims: When ecologically important plant traits are correlated they may be said to constitute an ecological 'strategy' dimension. Through identifying these dimensions and understanding their inter-relationships we gain insight into why particular trait combinations are favoured over others and into the implications of trait differences among species. Here we investigated relationships among several traits, and thus the strategy dimensions they represented, across 2134 woody species from seven Neotropical forests. • Methods: Six traits were studied: specific leaf area (SLA), the average size of leaves, seed and fruit, typical maximum plant height, and wood density (WD). Trait relationships …

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A Genome-Wide Scan Of Loci Linked To Serum Adiponectin In Two Populations Of African Descent, Chindo Hicks, Xiaofeng Zhu, Amy Luke, Donghui Kan, Adebowale Adeyemo, Xiaodong Wu, Richard S. Cooper May 2007

A Genome-Wide Scan Of Loci Linked To Serum Adiponectin In Two Populations Of African Descent, Chindo Hicks, Xiaofeng Zhu, Amy Luke, Donghui Kan, Adebowale Adeyemo, Xiaodong Wu, Richard S. Cooper

Faculty Publications

Objective: The objectives were to identify quantitative trait loci linked to serum adiponectin concentration and to estimate heritability in two populations of African descent. Research Methods and Procedures: We conducted a genome scan for serum adiponectin concentration in two populations of African descent. Genome-wide microsatelitte markers were typed in an African-American population consisting of 203 families from the Chicago area and in a Nigerian Yoruba population consisting of 146 families. Linkage analysis was performed to identify loci. Variance component model was used to estimate heritability. Results: Estimates of heritability adjusted for age, gender, and BMI were 0.45 and 0.70 for …

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Association Studies Of Bmi And Type 2 Diabetes In The Neuropeptide Y Pathway: A Possible Role For Npy2r As A Candidate Gene For Type 2 Diabetes In Men, Catarina D. Campbell, Helen N. Lyon, James Nemesh, Jared A. Drake, Tiinamaija Tuomi, Daniel Gaudet, Xiaofeng Zhu, Richard S. Cooper, Kristin G. Ardlie, Leif C. Groop, Joel N. Hirschhorn May 2007

Association Studies Of Bmi And Type 2 Diabetes In The Neuropeptide Y Pathway: A Possible Role For Npy2r As A Candidate Gene For Type 2 Diabetes In Men, Catarina D. Campbell, Helen N. Lyon, James Nemesh, Jared A. Drake, Tiinamaija Tuomi, Daniel Gaudet, Xiaofeng Zhu, Richard S. Cooper, Kristin G. Ardlie, Leif C. Groop, Joel N. Hirschhorn

Faculty Publications

The neuropeptide Y (NPY) family of peptides and receptors regulate food intake. Inherited variation in this pathway could influence susceptibility to obesity and its complications, including type 2 diabetes. We genotyped a set of 71 single nucleotide polymorphisms (SNPs) that capture the most common variation in NPY, PPY, PYY, NPY1R, NPY2R, and NPY5R in 2,800 individuals of recent European ancestry drawn from the near extremes of BMI distribution. Five SNPs located upstream of NPY2R were nominally associated with BMI in men (P values = 0.001-0.009, odds ratios [ORs] 1.27-1.34). No association with BMI was observed in women, and no consistent …

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Final Report: Shf Channel Modeling Over Sea-Based Test Ranges, Qiang Lei, Michael D. Rice Apr 2007

Final Report: Shf Channel Modeling Over Sea-Based Test Ranges, Qiang Lei, Michael D. Rice

Faculty Publications

This work was supported by the Science & Technology Test & Evaluation Spectrum Efficient Technologies Program sponsored by the US Air Force under contract F04611-02-C-0020. Channel sounding data collected from an airborne transmitter over the Pacific Ocean off the coast of Pt. Mugu, Naval Air Station, was analyzed and used to model multipath propagation over the ocean. The experiments showed that at 8.000 GHz, over the water multipath propagation is well modeled by a three-ray propagation model. The first ray (or propagation path) is the line-of-sight propagation path. The second ray is a strong specular reflection determined by the geometry …

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Mobile Dna In Old World Monkeys: A Glimpse Through The Rhesus Macaque Genome, Kyudong Han, Miriam K. Konkel, Jinchuan Xing, Hui Wang, Jungnam Lee, Thomas J. Meyer, Charles T. Huang, Erin Sandifer, Kristi Hebert, Erin W. Barnes, Robert Hubley, Webb Miller, Arian F.A. Smit, Brygg Ullmer, Mark A. Batzer Apr 2007

Mobile Dna In Old World Monkeys: A Glimpse Through The Rhesus Macaque Genome, Kyudong Han, Miriam K. Konkel, Jinchuan Xing, Hui Wang, Jungnam Lee, Thomas J. Meyer, Charles T. Huang, Erin Sandifer, Kristi Hebert, Erin W. Barnes, Robert Hubley, Webb Miller, Arian F.A. Smit, Brygg Ullmer, Mark A. Batzer

Faculty Publications

The completion of the draft sequence of the rhesus macaque genome allowed us to study the genomic composition and evolution of transposable elements in this representative of the Old World monkey lineage, a group of diverse primates closely related to humans. The L1 family of long interspersed elements appears to have evolved as a single lineage, and Alu elements have evolved into four currently active lineages. We also found evidence of elevated horizontal transmissions of retroviruses and the absence of DNA transposon activity in the Old World monkey lineage. In addition, ∼100 precursors of composite SVA (short interspersed element, variable …

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Evolutionary And Biomedical Insights From The Rhesus Macaque Genome, Richard A. Gibbs, Jeffrey Rogers, Michael G. Katze, Roger Bumgarner, George M. Weinstock, Elaine R. Mardis, Karin A. Remington, Robert L. Strausberg, J. Craig Venter, Richard K. Wilson, Mark A. Batzer, Carlos D. Bustamante, Evan E. Eichler, Matthew W. Hahn, Ross C. Hardison, Kateryna D. Makova, Webb Miller, Aleksandar Milosavljevic, Robert E. Palermo, Adam Siepel, James M. Sikela, Tony Attaway, Stephanie Bell, Kelly E. Bernard, Christian J. Buhay, Mimi N. Chandrabose, Marvin Dao, Clay Davis, Kimberly D. Delehaunty, Yan Ding, Huyen H. Dinh, Shannon Dugan-Rocha, Lucinda A. Fulton, Ramatu Ayiesha Gabisi Apr 2007

Evolutionary And Biomedical Insights From The Rhesus Macaque Genome, Richard A. Gibbs, Jeffrey Rogers, Michael G. Katze, Roger Bumgarner, George M. Weinstock, Elaine R. Mardis, Karin A. Remington, Robert L. Strausberg, J. Craig Venter, Richard K. Wilson, Mark A. Batzer, Carlos D. Bustamante, Evan E. Eichler, Matthew W. Hahn, Ross C. Hardison, Kateryna D. Makova, Webb Miller, Aleksandar Milosavljevic, Robert E. Palermo, Adam Siepel, James M. Sikela, Tony Attaway, Stephanie Bell, Kelly E. Bernard, Christian J. Buhay, Mimi N. Chandrabose, Marvin Dao, Clay Davis, Kimberly D. Delehaunty, Yan Ding, Huyen H. Dinh, Shannon Dugan-Rocha, Lucinda A. Fulton, Ramatu Ayiesha Gabisi

Faculty Publications

The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate …

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Accumulation Of Pathological Tau Species And Memory Loss In A Conditional Model Of Tauopathy, Zdenek Berger, Hanno Roder, Amanda Hanna, Vijayaraghavan Rangachari, Mei Yue, Zbigniew Wszolek, Karen Ashe, Joshua Knight, Dennis Dickson, Cathy Andorfer, Terrone L. Rosenberry, Jada Lewis, Mike Hutton, Christopher Janus Apr 2007

Accumulation Of Pathological Tau Species And Memory Loss In A Conditional Model Of Tauopathy, Zdenek Berger, Hanno Roder, Amanda Hanna, Vijayaraghavan Rangachari, Mei Yue, Zbigniew Wszolek, Karen Ashe, Joshua Knight, Dennis Dickson, Cathy Andorfer, Terrone L. Rosenberry, Jada Lewis, Mike Hutton, Christopher Janus

Faculty Publications

Neurofibrillary tangles (NFTs) are a pathological hallmark of Alzheimer's disease and other tauopathies, but recent studies in a conditional mouse model of tauopathy (rTg4510) have suggested that NFT formation can be dissociated from memory loss and neurodegeneration. This suggests that NFTs are not the major neurotoxic tau species, at least during the early stages of pathogenesis. To identify other neurotoxic tau protein species, we performed biochemical analyses on brain tissues from the rTg4510 mouse model and then correlated the levels of these tau proteins with memory loss. We describe the identification and characterization of two forms of tau multimers (140 …

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"And Also Many Animals": Biblical Resources For Preaching About Creation, Kathryn M. Schifferdecker Apr 2007

"And Also Many Animals": Biblical Resources For Preaching About Creation, Kathryn M. Schifferdecker

Faculty Publications

The Bible offers the preacher a multitude of texts for preaching about creation and the environment. Preachers can and should use these resources to call hearers to join in the creative and redemptive work of God, in the name of Christ and for the sake of the world.

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Displacing Dissent: The Role Of Place In First Amendment Jurisprudence, Thomas P. Crocker Apr 2007

Displacing Dissent: The Role Of Place In First Amendment Jurisprudence, Thomas P. Crocker

Faculty Publications

From the perspective of free speech theory, both of the central First Amendment values - human autonomy and deliberative democracy - require robust protection for the places and spaces in which speech and public discourse occur. This Article argues that current Supreme Court doctrine does not effectively protect speech from content neutral regulation of place. The problem is that remaining neutral is consistent with policies that would dislocate the very place for the "marketplace of ideas." Moreover, free speech theory focused on autonomy and deliberative democracy has not adequately addressed the role that place plays in furthering these values. Speech …

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Validation Of Commercial Dna Tests For Quantitative Beef Quality Traits, A. L. Van Eenennaam, J. Li, R. M. Thallman, R. L. Quaas, M. E. Dikeman, C. A. Gill, D. E. Franke, M. G. Thomas Apr 2007

Validation Of Commercial Dna Tests For Quantitative Beef Quality Traits, A. L. Van Eenennaam, J. Li, R. M. Thallman, R. L. Quaas, M. E. Dikeman, C. A. Gill, D. E. Franke, M. G. Thomas

Faculty Publications

Associations between 3 commercially available genetic marker panels (GeneSTAR Quality Grade, GeneSTAR Tenderness, and Igenity Tender-GENE) and quantitative beef traits were validated by the US National Beef Cattle Evaluation Consortium. Validation was interpreted to be the independent confirmation of the associations between genetic tests and phenotypes, as claimed by the commercial genotyping companies. Validation of the quality grade test (GeneSTAR Quality Grade) was carried out on 400 Charolais x Angus crossbred cattle, and validation of the tenderness tests (GeneSTAR Tenderness and Igenity Tender-GENE) was carried out on over 1,000 Bos taurus and Bos indicus cattle. The GeneSTAR Quality Grade marker …

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Interspecific Spawning Between A Recent Immigrant And An Endemic Damselfish (Pisces: Pomacentridae) In The Hawaiian Islands, Karen P. Maruska, Kimberly A. Peyton Apr 2007

Interspecific Spawning Between A Recent Immigrant And An Endemic Damselfish (Pisces: Pomacentridae) In The Hawaiian Islands, Karen P. Maruska, Kimberly A. Peyton

Faculty Publications

The Indo-Pacific damselfish Abudefduf vaigiensis (Quoy & Gaimard, 1825) was first observed in the Hawaiian Islands in the early 1990s and is now clearly established as a breeding population in the Islands. Sightings of fish with color patterns intermediate between those of A. vaigiensis and the very similar endemic Hawaiian sergeant, Abudefduf abdominalis (Quoy & Gaimard, 1825), suggest that hybridization of the two has occurred naturally. This study provides direct evidence of crossbreeding from observations and video footage of two separate spawnings in nearshore waters of O'ahu and a third spawning in a public aquarium display tank. Reproductive behaviors were …

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Induction Of Host Chemotactic Response By Encephalitozoon Spp., Jeffrey Fischer, Jeffrey West, Nnenaya Agochukwu, Colby Suire, Hollie Hale-Donze Apr 2007

Induction Of Host Chemotactic Response By Encephalitozoon Spp., Jeffrey Fischer, Jeffrey West, Nnenaya Agochukwu, Colby Suire, Hollie Hale-Donze

Faculty Publications

Microsporidians are a group of emerging pathogens typically associated with chronic diarrhea in immunocompromised individuals. The number of reports of infections with these organisms and the disseminated pathology is growing as diagnostic tools become more readily available. However, little is known about the innate immune response induced by and generated against these parasites. Using a coculture chemotaxis system, primary human macrophages were infected with Encephalitozoon cuniculi or Encephalitozoon intestinalis, and the recruitment of naïve monocytes was monitored. Encephalitozoon spp. induced an average threefold increase in migration of naïve cells 48 h postinfection, which corresponded to optimal infection of monocyte-derived- macrophages. …

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The Association Of A Snp Upstream Of Insig2 With Body Mass Index Is Reproduced In Several But Not All Cohorts, Helen N. Lyon, Valur Emilsson, Anke Hinney, Iris M. Heid, Jessica Lasky-Su, Xiaofeng Zhu, Gudmar Thorleifsson, Steinunn Gunnarsdottir, G. Bragi Walters, Unnur Thorsteinsdottir, Augustine Kong, Jeffrey Gulcher, Thuy Trang Nguyen, André Scherag, Arne Pfeufer, Thomas Meitinger, Günter Brönner, Winfried Rief, Manuel E. Soto-Quiros, Lydiana Avila, Barbara Klanderman, Benjamin A. Raby, Edwin K. Silverman, Scott T. Weiss, Nan Laird, Xiao Ding, Leif Groop, Tiinamaija Tuomi, Bo Isomaa, Kristina Bengtsson, Johannah L. Butler, Richard S. Cooper, Caroline S. Fox Apr 2007

The Association Of A Snp Upstream Of Insig2 With Body Mass Index Is Reproduced In Several But Not All Cohorts, Helen N. Lyon, Valur Emilsson, Anke Hinney, Iris M. Heid, Jessica Lasky-Su, Xiaofeng Zhu, Gudmar Thorleifsson, Steinunn Gunnarsdottir, G. Bragi Walters, Unnur Thorsteinsdottir, Augustine Kong, Jeffrey Gulcher, Thuy Trang Nguyen, André Scherag, Arne Pfeufer, Thomas Meitinger, Günter Brönner, Winfried Rief, Manuel E. Soto-Quiros, Lydiana Avila, Barbara Klanderman, Benjamin A. Raby, Edwin K. Silverman, Scott T. Weiss, Nan Laird, Xiao Ding, Leif Groop, Tiinamaija Tuomi, Bo Isomaa, Kristina Bengtsson, Johannah L. Butler, Richard S. Cooper, Caroline S. Fox

Faculty Publications

A SNP upstream of the INSIG2 gene, rs7566605, was recently found to be associated with obesity as measured by body mass index (BMI) by Herbert and colleagues. The association between increased BMI and homozygosity for the minor allele was first observed in data from a genome-wide association scan of 86,604 SNPs in 923 related individuals from the Framingham Heart Study offspring cohort. The association was reproduced in four additional cohorts, but was not seen in a fifth cohort. To further assess the general reproducibility of this association, we genotyped rs7566605 in nine large cohorts from eight populations across multiple ethnicities …

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Corin I555(P568) Allele Is Associated With Enhanced Cardiac Hypertrophic Response To Increased Systemic Afterload, J. Eduardo Rame, Mark H. Drazner, Wendy Post, Ronald Peshock, Joao Lima, Richard S. Cooper, Daniel L. Dries Apr 2007

Corin I555(P568) Allele Is Associated With Enhanced Cardiac Hypertrophic Response To Increased Systemic Afterload, J. Eduardo Rame, Mark H. Drazner, Wendy Post, Ronald Peshock, Joao Lima, Richard S. Cooper, Daniel L. Dries

Faculty Publications

Corin activates pro-A-type naturetic peptide and pro-B-type naturetic peptide into biologically active molecules. We recently identified a minor allele in the corin gene defined by 2 highly linked single nucleotide polymorphisms (T555I and Q568P), which was associated with hypertension in blacks. Because of the direct antihypertrophic effects of the natriuretic peptide system, we hypothesized that the minor corin I555(P568) allele would be associated with an enhanced hypertrophic response to pressure overload. The relationship between systolic blood pressure and indexed left ventricular mass, derived from cardiac MRI, was analyzed in the Dallas Heart Study as a function of corin allele status. …

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Paired Ig-Like Receptors Bind To Bacteria And Shape Tlr-Mediated Cytokine Production, Masafumi Nakayama, David M. Underhill, Timothy W. Petersen, Bin Li, Toshio Kitamura, Toshiyuki Takai, Alan Aderem Apr 2007

Paired Ig-Like Receptors Bind To Bacteria And Shape Tlr-Mediated Cytokine Production, Masafumi Nakayama, David M. Underhill, Timothy W. Petersen, Bin Li, Toshio Kitamura, Toshiyuki Takai, Alan Aderem

Faculty Publications

The innate immune system uses a wide variety of pattern recognition receptors including TLRs, scavenger receptors, and lectins to identify potential pathogens. A carefully regulated balance between activation and inhibition must be kept to avoid detrimental and inappropriate inflammatory responses. In this study, we identify murine-paired Ig-like receptor (PIR)-B, and its human orthologs Ig-like transcript 2 and Ig-like transcript 5 as novel receptors for Staphylococcus aureus. PIR-B contains four ITIM motifs and is thought to be an inhibitory receptor. Expression of these receptors enables NIH3T3 cells to bind S. aureus. In mouse bone marrow-derived macrophages, masking of PIR-B by anti-PIR …

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A Sine-Based Dichotomous Key For Primate Identification, Scott W. Herke, Jinchuan Xing, David A. Ray, Jacquelyn W. Zimmerman, Richard Cordaux, Mark A. Batzer Apr 2007

A Sine-Based Dichotomous Key For Primate Identification, Scott W. Herke, Jinchuan Xing, David A. Ray, Jacquelyn W. Zimmerman, Richard Cordaux, Mark A. Batzer

Faculty Publications

For DNA samples or 'divorced' tissues, identifying the organism from which they were taken generally requires some type of analytical method. The ideal approach would be robust even in the hands of a novice, requiring minimal equipment, time, and effort. Genotyping SINEs (Short INterspersed Elements) is such an approach as it requires only PCR-related equipment, and the analysis consists solely of interpreting fragment sizes in agarose gels. Modern primate genomes are known to contain lineage-specific insertions of Alu elements (a primate-specific SINE); thus, to demonstrate the utility of this approach, we used members of the Alu family to identify DNA …

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