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Effects Of Urbanization On The Occurrence Of Batrachochytrium Dendrobatidis: Do Urban Environments Provide Refuge From The Amphibian Chytrid Fungus?, Daniel Saenz, Taylor L. Hall, Matthew Kwiatkowski Jan 2015

Effects Of Urbanization On The Occurrence Of Batrachochytrium Dendrobatidis: Do Urban Environments Provide Refuge From The Amphibian Chytrid Fungus?, Daniel Saenz, Taylor L. Hall, Matthew Kwiatkowski

Faculty Publications

Batrachochytrium dendrobatidis (Bd) is a widespread pathogenic fungus that is known to cause the disease, chytridiomycosis, which can be lethal to many amphibians. We compared occurrence rates on spring peepers (Pseudacris crucifer) in urban and forested breeding sites in eastern Texas, USA. All study sites were at approximately the same latitude and altitude, and samples were collected at the same time of year to isolate differences in Bd infection rates between habitat types. We found significant differences (p<0.001) in the occurrence of Bd between habitats; with dramatically lower rates of occurrence at urban sites (19.5 %), compared to forested sites (62.9 …

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The War Against Crime: Ferguson, Police Militarization And The Third Amendment, Elizabeth Price Foley Jan 2015

The War Against Crime: Ferguson, Police Militarization And The Third Amendment, Elizabeth Price Foley

Faculty Publications

The shooting death of eighteen-year-old Michael Brown by Ferguson, Missouri police officer Darren Wilson has sparked a renewed national conversation about the militarization of police. While Officer Wilson’s deadly encounter with Brown did not involve militarized force, subsequent protests, looting, and riots have triggered the display and use of armored vehicles, M4 assault rifles, Humvees, Kevlar vests, grenades, camouflage, and other military-style equipment by state and local police. U.S. Attorney General Eric Holder criticized the police response, asserting, “At a time when we must seek to rebuild trust between law enforcement and the local community, I am deeply concerned that …

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Addressing Race And Racism In Early Childhood: Challenges And Opportunities, Flora Farago, Kay Sanders, Larissa Gaias Jan 2015

Addressing Race And Racism In Early Childhood: Challenges And Opportunities, Flora Farago, Kay Sanders, Larissa Gaias

Faculty Publications

This chapter draws on developmental intergroup theory, parental ethnic-racial socialization literature, anti-bias curricula, and prejudice intervention studies to address the appropriateness of discussing race and racism in early childhood settings. Existing literature about teacher discussions surrounding race and racism is reviewed, best practices are shared, and the need for more research in this area is highlighted. The construct of parental ethnic-racial socialization is mapped onto early childhood anti-bias classroom practices. The chapter also outlines racial ideologies of teachers, specifically anti-bias and colorblind attitudes, and discusses how these ideologies may manifest in classroom practices surrounding race and racism. Colorblind ideology is …

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Improving Regulatory Enforcement In The Face Of Inadequate Resources, Sharona Hoffman Jan 2015

Improving Regulatory Enforcement In The Face Of Inadequate Resources, Sharona Hoffman

Faculty Publications

This article is a teaching exercise, designed to focus students’ attention on the challenges of regulatory enforcement. It grows out of the author’s Robert Wood Johnson Foundation Public Health Law Fellowship during which she worked with the Oregon Health Authority. The case example is drawn from Oregon’s regulation of in-home care agencies (IHCA). Students are asked to formulate suggestions for enhancing compliance with IHCA regulations in the absence of additional funding. The author includes her own recommendations for positive and negative incentives for regulatory compliance, which she developed during her fellowship.

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Stereo Photo Series For Estimating Natural Fuels In The Netherlands Volume 3: Veen, Brian P. Oswald Jan 2015

Stereo Photo Series For Estimating Natural Fuels In The Netherlands Volume 3: Veen, Brian P. Oswald

Faculty Publications

The photo series is a collection of photos and associated field data representing a region of The Netherlands. Volume 3 includes peatland vegetation types located in Northumberland National Park in England. These sites were used to represent those found in The Netherlands since peatlands in the UK are larger and thereby better for the field research. For each vegetation type, sites were sampled with varying fuel loads. The description of the sites consists of a wide-angle site photo, supplemented with field data on the various fuel loads and vegetative layers. The photo series is an important ecological tool to assess …

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Seasonal Variation Of Colored Dissolved Organic Matter In Barataria Bay, Louisiana, Using Combined Landsat And Field Data, I. Joshi, E.J. D'Sa Jan 2015

Seasonal Variation Of Colored Dissolved Organic Matter In Barataria Bay, Louisiana, Using Combined Landsat And Field Data, I. Joshi, E.J. D'Sa

Faculty Publications

No abstract provided.

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Patterns Of Seed Bank And Vegetation Diversity Along A Tidal Freshwater River, Tracy Elsey-Quirk, Mary Allessio Leck Jan 2015

Patterns Of Seed Bank And Vegetation Diversity Along A Tidal Freshwater River, Tracy Elsey-Quirk, Mary Allessio Leck

Faculty Publications

No abstract provided.

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Human Impacts On Fisheries Across The Land-Sea Interface, N.N. Rabalais Jan 2015

Human Impacts On Fisheries Across The Land-Sea Interface, N.N. Rabalais

Faculty Publications

No abstract provided.

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Application Of Otolith Chemical Signatures To Estimate Population Connectivity Of Red Snapper In The Western Gulf Of Mexico, Michelle Zapp Sluis, Beverly K. Barnett, William F. Patterson, James H. Cowan, Alan M. Shiller Jan 2015

Application Of Otolith Chemical Signatures To Estimate Population Connectivity Of Red Snapper In The Western Gulf Of Mexico, Michelle Zapp Sluis, Beverly K. Barnett, William F. Patterson, James H. Cowan, Alan M. Shiller

Faculty Publications

Otolith chemical signatures of Red Snapper Lutjanus campechanus from six nursery regions were used to estimate the sources of recruits to four sampling regions in the western Gulf of Mexico (Gulf) and to estimate whether postsettlement mixing of Red Snapper occurs between the U.S. and Mexican portions of the western Gulf. In a previous study, region-specific otolith signatures (element : Ca ratios: Ba:Ca, Mg:Ca, Mn:Ca, Sr:Ca, and Li:Ca; stable isotope delta values: δ13C and δ18O) were developed based on age-0 Red Snapper (2005–2007 year-classes) sampled from the six nursery areas. In the present study, subadult and …

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Writing About Aj Pop B'Atz': Bruce Grindal And The Transformation Of Ethnographic Writing, Sarah Ashley Kistler Jan 2015

Writing About Aj Pop B'Atz': Bruce Grindal And The Transformation Of Ethnographic Writing, Sarah Ashley Kistler

Faculty Publications

The works of Bruce Grindal teach us many things about anthropology’s humanistic tradition. With examples such as Redneck Girl and “Postmodernism as Seen by the Boys at Downhome Auto Repair,” Bruce Grindal demonstrated how we can creatively engage our ethnographic writing to reflect lived experiences. In this article, I examine Bruce’s influence on my ethnographic writing and collaborative research in the Maya community of San Juan Chamelco, Guatemala. Since 2006, I have worked collectively with a group of Chamelqueños to investigate the story of their local hero, Aj Pop B’atz’. In the sixteenth century, Aj Pop B’atz’ welcomed Spanish invaders …

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When Does Flexibility Matter In Environmental Law?, Josh Eagle Jan 2015

When Does Flexibility Matter In Environmental Law?, Josh Eagle

Faculty Publications

Environmental law scholars, practitioners, and policymakers have wrestled for some time with the implications of climate change for environmental law. There is widespread, although not universal, agreement that climate change requires greater flexibility in environmental legal systems. Flexibility-reduced procedural requirements for administrative agency decision making and less rigid substantive standards-would allow the agencies that implement environmental law to adapt to a future world characterized by dynamic, uncertain changes in natural resource systems. According to its proponents, flexibility would make it easier for agencies to more frequently update their management or regulatory decisions to respond to changed conditions, and also to …

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Regulating The Underground: Secret Supper Clubs, Pop-Up Restaurants And The Role O F Law, Sarah B. Schindler Jan 2015

Regulating The Underground: Secret Supper Clubs, Pop-Up Restaurants And The Role O F Law, Sarah B. Schindler

Faculty Publications

Instagram pictures of elegantly plated dinners, long farmstyle tables, and well-to-do people laughing in what looks like a loft apartment are followed by commenters asking, “Where is this?” This is the world of underground dining. Aspiring and established chefs invite strangers into their homes (or their friends’ stores after hours, or the empty warehouse at the edge of town, or the nearest farm) for a night of food and revelry in exchange for cash. Although decidedly antiestablishment, these secret suppers and pop-up restaurants are popular—there are websites to help people locate them, and many respected publications have penned stories about …

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Ingroup Bias And Ingroup Projection In The Furry Fandom, Stephen Reysen, Courtney N. Plante, Sharon E. Roberts, Kathleen C. Gerbasi Jan 2015

Ingroup Bias And Ingroup Projection In The Furry Fandom, Stephen Reysen, Courtney N. Plante, Sharon E. Roberts, Kathleen C. Gerbasi

Faculty Publications

In two studies, we examine ingroup favoritism within the furry community. Furry fans construct personas (“fursonas”) that are often related to a species of animal (e.g., fox, wolf). In Study 1, furries were found to rate their fursona species more favorably than other species. In Study 2, we examined whether the ingroup projection model may aid in understanding this ingroup species bias. Participants’ ratings of prototypicality of their species within the fandom was associated with greater favoritism of one’s species. A serial mediation model showed that identification with the fursona and perceived benefits of one’s fursona mediated the association between …

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Using Life History Trade-Offs To Understand Core-Transient Structuring Of A Small Mammal Community, Sarah R. Supp, David N. Koons, S. K. Ernest Jan 2015

Using Life History Trade-Offs To Understand Core-Transient Structuring Of A Small Mammal Community, Sarah R. Supp, David N. Koons, S. K. Ernest

Faculty Publications

No abstract provided.

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Localisation Of 11Β-Hydroxysteroid Dehydrogenase Type 2 In Mineralocorticoid Receptor Expressing Magnocellular Neurosecretory Neurones Of The Rat Supraoptic And Paraventricular Nuclei, M. Haque, R. Wilson, K. Sharma, N. J. Mills, R. Teruyama Jan 2015

Localisation Of 11Β-Hydroxysteroid Dehydrogenase Type 2 In Mineralocorticoid Receptor Expressing Magnocellular Neurosecretory Neurones Of The Rat Supraoptic And Paraventricular Nuclei, M. Haque, R. Wilson, K. Sharma, N. J. Mills, R. Teruyama

Faculty Publications

© 2015 British Society for Neuroendocrinology. An accumulating body of evidence suggests that the activity of the mineralocorticoid, aldosterone, in the brain via the mineralocorticoid receptor (MR) plays an important role in the regulation of blood pressure. MR was recently found in vasopressin and oxytocin synthesising magnocellular neurosecretory cells (MNCs) in both the paraventricular (PVN) and supraoptic (SON) nuclei in the hypothalamus. Considering the physiological effects of these hormones, MR in these neurones may be an important site mediating the action of aldosterone in blood pressure regulation within the brain. However, aldosterone activation of MR in the hypothalamus remains controversial …

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Il-1Β Reciprocally Regulates Chemokine And Insulin Secretion In Pancreatic Β-Cells Via Nf-Κb, Susan J. Burke, Krisztian Stadler, Danhong Lu, Evanna Gleason, Anna Han, Dallas R. Donohoe, Richard C. Rogers, Gerlinda E. Hermann, Michael D. Karlstad, J. Jason Collier Jan 2015

Il-1Β Reciprocally Regulates Chemokine And Insulin Secretion In Pancreatic Β-Cells Via Nf-Κb, Susan J. Burke, Krisztian Stadler, Danhong Lu, Evanna Gleason, Anna Han, Dallas R. Donohoe, Richard C. Rogers, Gerlinda E. Hermann, Michael D. Karlstad, J. Jason Collier

Faculty Publications

© 2015 the American Physiological Society. Proinflammatory cytokines impact islet β-cell mass and function by altering the transcriptional activity within pancreatic β-cells, producing increases in intracellular nitric oxide abundance and the synthesis and secretion of immunomodulatory proteins such as chemokines. Herein, we report that IL-1β, a major mediator of inflammatory responses associated with diabetes development, coordinately and reciprocally regulates chemokine and insulin secretion. We discovered that NF-κB controls the increase in chemokine transcription and secretion as well as the decrease in both insulin secretion and proliferation in response to IL-1β. Nitric oxide production, which is markedly elevated in pancreatic β-cells …

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Respiratory Syncytial Virus Disease Is Mediated By Age-Variable Il-33, Jordy Saravia, Dahui You, Bishwas Shrestha, Sridhar Jaligama, David Siefker, Greg I. Lee, Jeffrey N. Harding, Tamekia L. Jones, Cynthia Rovnaghi, Bindiya Bagga, John P. Devincenzo, Stephania A. Cormier Jan 2015

Respiratory Syncytial Virus Disease Is Mediated By Age-Variable Il-33, Jordy Saravia, Dahui You, Bishwas Shrestha, Sridhar Jaligama, David Siefker, Greg I. Lee, Jeffrey N. Harding, Tamekia L. Jones, Cynthia Rovnaghi, Bindiya Bagga, John P. Devincenzo, Stephania A. Cormier

Faculty Publications

© 2015 Saravia et al. Respiratory syncytial virus (RSV) is the most common cause of infant hospitalizations and severe RSV infections are a significant risk factor for childhood asthma. The pathogenic mechanisms responsible for RSV induced immunopathophysiology remain elusive. Using an age-appropriate mouse model of RSV, we show that IL-33 plays a critical role in the immunopathogenesis of severe RSV, which is associated with higher group 2 innate lymphoid cells (ILC2s) specifically in neonates. Infection with RSV induced rapid IL-33 expression and an increase in ILC2 numbers in the lungs of neonatal mice; this was not observed in adult mice. …

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Mechanistic Species Distribution Modelling As A Link Between Physiology And Conservation, Tyler G. Evans, Sarah E. Diamond, Morgan W. Kelly Jan 2015

Mechanistic Species Distribution Modelling As A Link Between Physiology And Conservation, Tyler G. Evans, Sarah E. Diamond, Morgan W. Kelly

Faculty Publications

© The Author 2015. Climate change conservation planning relies heavily on correlative species distribution models that estimate future areas of occupancy based on environmental conditions encountered in present-day ranges. The approach benefits from rapid assessment of vulnerability over a large number of organisms, but can have poor predictive power when transposed to novel environments and reveals little in the way of causal mechanisms that define changes in species distribution or abundance. Having conservation planning rely largely on this single approach also increases the risk of policy failure. Mechanistic models that are parameterized with physiological information are expected to be more …

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Physiological Strategies During Animal Diapause: Lessons From Brine Shrimp And Annual Killifish, Jason E. Podrabsky, Steven C. Hand Jan 2015

Physiological Strategies During Animal Diapause: Lessons From Brine Shrimp And Annual Killifish, Jason E. Podrabsky, Steven C. Hand

Faculty Publications

© 2015. Published by The Company of Biologists Ltd. Diapause is a programmed state of developmental arrest that typically occurs as part of the natural developmental progression of organisms that inhabit seasonal environments. The brine shrimp Artemia franciscana and annual killifish Austrofundulus limnaeus share strikingly similar life histories that include embryonic diapause as a means to synchronize the growth and reproduction phases of their life history to favorable environmental conditions. In both species, respiration rate is severely depressed during diapause and thus alterations in mitochondrial physiology are a key component of the suite of characters associated with cessation of development. …

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Divergent Evolution Of Two Corticotropin-Releasing Hormone (Crh) Genes In Teleost Fishes, Brian P. Grone, Karen P. Maruska Jan 2015

Divergent Evolution Of Two Corticotropin-Releasing Hormone (Crh) Genes In Teleost Fishes, Brian P. Grone, Karen P. Maruska

Faculty Publications

© 2015 Grone and Maruska. Genome duplication, thought to have happened twice early in vertebrate evolution and a third time in teleost fishes, gives rise to gene paralogs that can evolve subfunctions or neofunctions via sequence and regulatory changes. To explore the evolution and functions of corticotropin-releasing hormone (CRH), we searched sequenced teleost genomes for CRH paralogs. Our phylogenetic and synteny analyses indicate that two CRH genes, crha and crhb, evolved via duplication of crh1 early in the teleost lineage. We examined the expression of crha and crhb in two teleost species from different orders: an African cichlid, Burton's mouthbrooder, …

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The Effect Of Habitat And Body Size On The Evolution Of Vocal Displays In Thraupidae (Tanagers), The Largest Family Of Songbirds, Nicholas A. Mason, Kevin J. Burns Jan 2015

The Effect Of Habitat And Body Size On The Evolution Of Vocal Displays In Thraupidae (Tanagers), The Largest Family Of Songbirds, Nicholas A. Mason, Kevin J. Burns

Faculty Publications

© 2015 The Linnean Society of London. Animals rely on auditory cues to relay important information between individuals regarding territoriality, mating status, and individual condition. The efficacy of acoustic signals can depend on many factors, including the transmitter, the receiver, and the signalling environment. In the present study, we evaluate the effect of body size and habitat on the evolution of learned vocal displays across the tanagers (Aves: Thraupidae), a group that comprises nearly 10% of all songbird species. We find that body size affects tanager vocalizations, such that nine out of ten song characters and scores from two principal …

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How Global Biodiversity Hotspots May Go Unrecognized: Lessons From The North American Coastal Plain, Reed F. Noss, William J. Platt, Bruce A. Sorrie, Alan S. Weakley, D. Bruce Means, Jennifer Costanza, Robert K. Peet Jan 2015

How Global Biodiversity Hotspots May Go Unrecognized: Lessons From The North American Coastal Plain, Reed F. Noss, William J. Platt, Bruce A. Sorrie, Alan S. Weakley, D. Bruce Means, Jennifer Costanza, Robert K. Peet

Faculty Publications

© 2014 John Wiley & Sons Ltd. Biodiversity hotspots are conservation priorities. We identify the North American Coastal Plain (NACP) as a global hotspot based on the classic definition, a region with > 1500 endemic plant species and > 70% habitat loss. This region has been bypassed in prior designations due to misconceptions and myths about its ecology and history. These fallacies include: (1) young age of the NACP, climatic instability over time and submergence during high sea-level stands; (2) climatic and environmental homogeneity; (3) closed forest as the climax vegetation; and (4) fire regimes that are mostly anthropogenic. We show that …

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African Fire Cultures, Cattle Ranching, And Colonial Landscape Transformations In The Neotropics, Andrew Sluyter, Chris Duvall Jan 2015

African Fire Cultures, Cattle Ranching, And Colonial Landscape Transformations In The Neotropics, Andrew Sluyter, Chris Duvall

Faculty Publications

Fire regimes emerge partly from human activities that reflect cultural-ecological knowledge of the relationships among fire, vegetation, grazing, climate, and other variables, as well as social relations. More knowledge of such “fire cultures,” past and present, therefore remains necessary to better understand the causes and persistent consequences of landscape burning. In the neotropics, people have used fire for centuries to manage livestock pastures. Conventional wisdom has long posited that such practices derived solely from antecedent European and indigenous, Native American fire cultures. Analysis of accounts of rangeland burning from throughout the neotropics during colonial times, however, demonstrates that ranchers incorporated …

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Leptin Deficient Ob/Ob Mice And Diet-Induced Obese Mice Responded Differently To Roux-En-Y Bypass Surgery, Z. Hao, H. Münzberg, K. Rezai-Zadeh, M. Keenan, D. Coulon, H. Lu, H. R. Berthoud, J. Ye Jan 2015

Leptin Deficient Ob/Ob Mice And Diet-Induced Obese Mice Responded Differently To Roux-En-Y Bypass Surgery, Z. Hao, H. Münzberg, K. Rezai-Zadeh, M. Keenan, D. Coulon, H. Lu, H. R. Berthoud, J. Ye

Faculty Publications

© 2015 Macmillan Publishers Limited. Weight regain contributes to the therapeutic failure in 15-20% of type 2 diabetic patients after Roux-en-Y gastric bypass surgery (RYGB), and the mechanism remains largely unknown. This study was conducted to explore the mechanism of weight regain.Research design:Wild-type (WT) diet-induced obese (DIO) mice were used to mimic human obesity, and ob/ob mice were used for leptin deficiency-induced obesity. Two groups of mice were compared in weight regain for 10 months after RYGB. Weight loss, food intake, fecal energy loss and energy expenditure were monitored in the study of weight regain. Fasting insulin, insulin tolerance and …

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Role Of Resistant Starch In Improving Gut Health, Adiposity, And Insulin Resistance, Michael J. Keenan, June Zhou, Maren Hegsted, Christine Pelkman, Holiday A. Durham, Diana B. Coulon, Roy J. Martin Jan 2015

Role Of Resistant Starch In Improving Gut Health, Adiposity, And Insulin Resistance, Michael J. Keenan, June Zhou, Maren Hegsted, Christine Pelkman, Holiday A. Durham, Diana B. Coulon, Roy J. Martin

Faculty Publications

© 2015 American Society for Nutrition. The realization that low-glycemic index diets were formulated using resistant starch led to more than a decade of research on the health effects of resistant starch. Determination of the metabolizable energy of the resistant starch product allowed for the performance of isocaloric studies. Fermentation of resistant starch in rodent studies results in what appears to be a healthier gut, demonstrated by increased amounts of short-chain fatty acids, an apparent positive change in the microbiota, and increased gene expression for gene products involved in normal healthy proliferation and apoptosis of potential cancer cells. Additionally, consumption …

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Photoactivated Mir-148b-Nanoparticle Conjugates Improve Closure Of Critical Size Mouse Calvarial Defects, Ammar T. Qureshi, Andrew Doyle, Cong Chen, Diana Coulon, Vinod Dasa, Fabio Delpiero, Benjamin Levi, W. Todd Monroe, Jeffrey M. Gimble, Daniel J. Hayes Jan 2015

Photoactivated Mir-148b-Nanoparticle Conjugates Improve Closure Of Critical Size Mouse Calvarial Defects, Ammar T. Qureshi, Andrew Doyle, Cong Chen, Diana Coulon, Vinod Dasa, Fabio Delpiero, Benjamin Levi, W. Todd Monroe, Jeffrey M. Gimble, Daniel J. Hayes

Faculty Publications

© 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. Inducible systems providing temporal control of differentiation have the potential to improve outcomes in surgical reconstruction and regenerative medicine by precise modulation of wound healing and tissue repair processes. The aim of this study was to demonstrate that nanoformulated microRNA (miRNA) conjugates activated via photo exposure can lead to the induced osteogenic differentiation of human adipose-derived stromal/stem cells (hASCs) in vivo. The conjugate PC-miR-148b-SNP, a mimic of miRNA-148b tethered to silver nanoparticles (SNPs) via a photolabile linker, was used to modulate gene expression for improved closure of a …

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Leptin Deficient Ob/Ob Mice And Diet-Induced Obese Mice Responded Differently To Roux-En-Y Bypass Surgery, Z. Hao, H. Münzberg, K. Rezai-Zadeh, M. Keenan, D. Coulon, H. Lu, H. R. Berthoud, J. Ye Jan 2015

Leptin Deficient Ob/Ob Mice And Diet-Induced Obese Mice Responded Differently To Roux-En-Y Bypass Surgery, Z. Hao, H. Münzberg, K. Rezai-Zadeh, M. Keenan, D. Coulon, H. Lu, H. R. Berthoud, J. Ye

Faculty Publications

© 2015 Macmillan Publishers Limited. Weight regain contributes to the therapeutic failure in 15-20% of type 2 diabetic patients after Roux-en-Y gastric bypass surgery (RYGB), and the mechanism remains largely unknown. This study was conducted to explore the mechanism of weight regain.Research design:Wild-type (WT) diet-induced obese (DIO) mice were used to mimic human obesity, and ob/ob mice were used for leptin deficiency-induced obesity. Two groups of mice were compared in weight regain for 10 months after RYGB. Weight loss, food intake, fecal energy loss and energy expenditure were monitored in the study of weight regain. Fasting insulin, insulin tolerance and …

Go to article

Role Of Resistant Starch In Improving Gut Health, Adiposity, And Insulin Resistance, Michael J. Keenan, June Zhou, Maren Hegsted, Christine Pelkman, Holiday A. Durham, Diana B. Coulon, Roy J. Martin Jan 2015

Role Of Resistant Starch In Improving Gut Health, Adiposity, And Insulin Resistance, Michael J. Keenan, June Zhou, Maren Hegsted, Christine Pelkman, Holiday A. Durham, Diana B. Coulon, Roy J. Martin

Faculty Publications

© 2015 American Society for Nutrition. The realization that low-glycemic index diets were formulated using resistant starch led to more than a decade of research on the health effects of resistant starch. Determination of the metabolizable energy of the resistant starch product allowed for the performance of isocaloric studies. Fermentation of resistant starch in rodent studies results in what appears to be a healthier gut, demonstrated by increased amounts of short-chain fatty acids, an apparent positive change in the microbiota, and increased gene expression for gene products involved in normal healthy proliferation and apoptosis of potential cancer cells. Additionally, consumption …

Go to article

Photoactivated Mir-148b-Nanoparticle Conjugates Improve Closure Of Critical Size Mouse Calvarial Defects, Ammar T. Qureshi, Andrew Doyle, Cong Chen, Diana Coulon, Vinod Dasa, Fabio Delpiero, Benjamin Levi, W. Todd Monroe, Jeffrey M. Gimble, Daniel J. Hayes Jan 2015

Photoactivated Mir-148b-Nanoparticle Conjugates Improve Closure Of Critical Size Mouse Calvarial Defects, Ammar T. Qureshi, Andrew Doyle, Cong Chen, Diana Coulon, Vinod Dasa, Fabio Delpiero, Benjamin Levi, W. Todd Monroe, Jeffrey M. Gimble, Daniel J. Hayes

Faculty Publications

© 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. Inducible systems providing temporal control of differentiation have the potential to improve outcomes in surgical reconstruction and regenerative medicine by precise modulation of wound healing and tissue repair processes. The aim of this study was to demonstrate that nanoformulated microRNA (miRNA) conjugates activated via photo exposure can lead to the induced osteogenic differentiation of human adipose-derived stromal/stem cells (hASCs) in vivo. The conjugate PC-miR-148b-SNP, a mimic of miRNA-148b tethered to silver nanoparticles (SNPs) via a photolabile linker, was used to modulate gene expression for improved closure of a …

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Prowashonupana Barley Dietary Fibre Reduces Body Fat And Increases Insulin Sensitivity In Caenorhabditis Elegans Model, Chenfei Gao, Michael L. King, Zachary L. Fitzpatrick, Wenqian Wei, Jason F. King, Mingming Wang, Frank L. Greenway, John W. Finley, Jeffrey H. Burton, William D. Johnson, Michael J. Keenan, Frederick M. Enright, Roy J. Martin, Jolene Zheng Jan 2015

Prowashonupana Barley Dietary Fibre Reduces Body Fat And Increases Insulin Sensitivity In Caenorhabditis Elegans Model, Chenfei Gao, Michael L. King, Zachary L. Fitzpatrick, Wenqian Wei, Jason F. King, Mingming Wang, Frank L. Greenway, John W. Finley, Jeffrey H. Burton, William D. Johnson, Michael J. Keenan, Frederick M. Enright, Roy J. Martin, Jolene Zheng

Faculty Publications

© 2015 Elsevier Ltd. Prowashonupana barley (PWB) is high in β-glucan with moderate content of resistant starch. PWB reduced intestinal fat deposition (IFD) in wild type Caenorhabditis elegans (C. elegans, N2), and in sir-2.1 or daf-16 null mutants, and sustained a surrogate marker of lifespan, pharyngeal pumping rate (PPR), in N2, sir-2.1, daf-16, or daf-16/daf-2 mutants. Hyperglycaemia (2% glucose) reversed or reduced the PWB effect on IFD in N2 or daf-16/daf-2 mutants with a sustained PPR. mRNA expression of cpt-1, cpt-2, ckr-1, and gcy-8 were dose-dependently reduced in N2 or daf-16 mutants, elevated in daf-16/daf-2 mutants with reduction in cpt-1, …

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