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Faculty Publications

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The Microbiome Stress Project: Toward A Global Meta-Analysis Of Environmental Stressors And Their Effects On Microbial Communities, Jennifer D. Rocca, Marie Simonin, Joanna R. Blaszczak, Jessica G. Ernakovich, Sean M. Gibbons, Firas S. Midani, Alex D. Washburne Jan 2019

The Microbiome Stress Project: Toward A Global Meta-Analysis Of Environmental Stressors And Their Effects On Microbial Communities, Jennifer D. Rocca, Marie Simonin, Joanna R. Blaszczak, Jessica G. Ernakovich, Sean M. Gibbons, Firas S. Midani, Alex D. Washburne

Faculty Publications

Microbial community structure is highly sensitive to natural (e.g., drought, temperature, fire) and anthropogenic (e.g., heavy metal exposure, land-use change) stressors. However, despite an immense amount of data generated, systematic, cross-environment analyses of microbiome responses to multiple disturbances are lacking. Here, we present the Microbiome Stress Project, an open-access database of environmental and host-associated 16S rRNA amplicon sequencing studies collected to facilitate cross-study analyses of microbiome responses to stressors. This database will comprise published and unpublished datasets re-processed from the raw sequences into exact sequence variants using our standardized computational pipeline. Our database will provide insight into general response patterns …

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Etoxpred: A Machine Learning-Based Approach To Estimate The Toxicity Of Drug Candidates 11 Medical And Health Sciences 1115 Pharmacology And Pharmaceutical Sciences 03 Chemical Sciences 0305 Organic Chemistry 03 Chemical Sciences 0304 Medicinal And Biomolecular Chemistry, Limeng Pu, Misagh Naderi, Tairan Liu, Hsiao Chun Wu, Supratik Mukhopadhyay, Michal Brylinski Jan 2019

Etoxpred: A Machine Learning-Based Approach To Estimate The Toxicity Of Drug Candidates 11 Medical And Health Sciences 1115 Pharmacology And Pharmaceutical Sciences 03 Chemical Sciences 0305 Organic Chemistry 03 Chemical Sciences 0304 Medicinal And Biomolecular Chemistry, Limeng Pu, Misagh Naderi, Tairan Liu, Hsiao Chun Wu, Supratik Mukhopadhyay, Michal Brylinski

Faculty Publications

© 2019 The Author(s). Background: The efficiency of drug development defined as a number of successfully launched new pharmaceuticals normalized by financial investments has significantly declined. Nonetheless, recent advances in high-throughput experimental techniques and computational modeling promise reductions in the costs and development times required to bring new drugs to market. The prediction of toxicity of drug candidates is one of the important components of modern drug discovery. Results: In this work, we describe eToxPred, a new approach to reliably estimate the toxicity and synthetic accessibility of small organic compounds. eToxPred employs machine learning algorithms trained on molecular fingerprints to …

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Trophodynamics And Mercury Bioaccumulation In Reef And Open-Ocean Fishes From The Bahamas With A Focus On Two Teleost Predators, Oliver N. Shipley, Cheng Shiuan Lee, Nicholas S. Fisher, Georgiana Burruss, Michael G. Frisk, Edward J. Brooks, Zachary C. Zuckerman, Achim D. Herrmann, Daniel J. Madigan Jan 2019

Trophodynamics And Mercury Bioaccumulation In Reef And Open-Ocean Fishes From The Bahamas With A Focus On Two Teleost Predators, Oliver N. Shipley, Cheng Shiuan Lee, Nicholas S. Fisher, Georgiana Burruss, Michael G. Frisk, Edward J. Brooks, Zachary C. Zuckerman, Achim D. Herrmann, Daniel J. Madigan

Faculty Publications

© Inter-Research 2019. Identifying prey resource pools supporting fish biomass can elucidate trophic pathways of pollutant bioaccumulation. We used multiple chemical tracers (carbon [δ 13 C] and nitrogen [δ 15 N] stable isotopes and total mercury [THg]) to identify trophic pathways and measure contaminant loading in upper trophic level fishes residing at a reef and open-ocean interface near Eleuthera in the Exuma Sound, The Bahamas. We focused predominantly on the trophic pathways of mercury bioaccumulation in dolphinfish Coryphaena hippurus and wahoo Acanthocybium solandri, 2 commonly consumed pelagic sportfish in the region. Despite residing within close proximity to productive and extensive …

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Global Patterns And Drivers Of Ecosystem Functioning In Rivers And Riparian Zones, Scott D. Tiegs, David M. Costello, Mark W. Isken, Guy Woodward, Peter B. Mcintyre, Mark O. Gessner, Eric Chauvet, Natalie A. Griffiths, Alex S. Flecker, Vicenç Acuña, Ricardo Albariño, Daniel C. Allen, Cecilia Alonso, Patricio Andino, Clay Arango, Jukka Aroviita, Marcus V.M. Barbosa, Leon A. Barmuta, Denise A. Bruesewitz, Francis J. Burdon, Marcos Callisto, Cristina Canhoto, Krista A. Capps, Maria M. Castillo, Joanne Clapcott, Fanny Colas, Checo Checo Colón-Gaud, Julien Cornut, Verónica Crespo-Pérez, Wyatt F. Cross, Joseph M. Culp, Michael Danger, Olivier Dangles, Elvira De Eyto, Alison M. Derry, Veronica Díaz Villanueva, Michael M. Douglas, Arturo Elosegi, Andrea C. Encalada, Sally Entrekin, Rodrigo Espinosa, Diana Ethaiya, Verónica Ferreira, Carmen Ferriol, Kyla M. Flanagan, Tadeusz Fleituch, Jennifer J. Follstad Shah, André Frainer, Nikolai Friberg, Paul C. Frost, Erica A. Garcia, Liliana García Lago, Pavel Ernesto García Soto, Sudeep Ghate, Darren P. Giling, Alan Gilmer, José Franciso Gonçalves Jr., Rosario Karina Gonzales, Manuel A.S. Graça, Mike Grace, Hans-Peter Grossart, François Guérold, Vlad Gulis, Luiz U. Hepp, Scott Higgins, Takuo Hishi, Joseph Huddart, John Hudson, Samantha Imberger, Carlos Iñiguez-Armijos, Tomoya Iwata, David J. Janetski, Eleanor Jennings, Andrea E. Kirkwood, Aaron A. Koning, Sarian Kosten, Kevin A. Kuehn, Hjalmar Laudon, Peter R. Leavitt, Aurea L. Lemes Da Silva, Shawn G. Leroux, Carri J. Leroy, Peter J. Lisi, Richard Mackenzie, Amy M. Marcarelli, Frank O. Masese, Brendan G. Mckie, Adriana Oliveira Medeiros, Kristian Meissner, Marko Miliša, Shailendra Mishra, Yo Miyake, Ashley Moerke, Shorok Mombrikotb, Rob Mooney, Tim Moulton, Timo Muotka, Junjiro N. Negishi, Vinicius Neres-Lima, Mika L. Nieminen, Jorge Nimptsch, Jakub Ondruch, Riku Paavola, Isabel Pardo, Christopher J. Patrick, Edwin T.H.M. Peeters, Jesus Pozo, Catherine Pringle, Aaron Prussian, Estefania Quenta, Antonio Quesada, Brian Reid, John S. Richardson, Anna Rigosi, José Rincón, Geta Rîșnoveanu, Christopher T. Robinson, Lorena Rodríguez-Gallego, Todd V. Royer, James A. Rusak, Anna C. Santamans, Géza B. Selmeczy, Gelas Simiyu, Agnija Skuja, Jerzy Smykla, Kandikere R. Sridhar, Ryan Sponseller, Aaron Stoler, Christopher M. Swan, David Szlag, Franco Teixera-De Mello, Jonathan D. Tonkin, Sari Uusheimo, Allison M. Veach, Sirje Vilbaste, Lena B.M. Vought, Chiao-Ping Wang, Jackon R. Webster, Paul B. Wilson, Stefan Woelfl, Marguerite A. Xenopolous, Adam G. Yates, Chihiro Yoshimura, Catherine M. Yule, Yixin X. Zhang, Jacob A. Zwart Jan 2019

Global Patterns And Drivers Of Ecosystem Functioning In Rivers And Riparian Zones, Scott D. Tiegs, David M. Costello, Mark W. Isken, Guy Woodward, Peter B. Mcintyre, Mark O. Gessner, Eric Chauvet, Natalie A. Griffiths, Alex S. Flecker, Vicenç Acuña, Ricardo Albariño, Daniel C. Allen, Cecilia Alonso, Patricio Andino, Clay Arango, Jukka Aroviita, Marcus V.M. Barbosa, Leon A. Barmuta, Denise A. Bruesewitz, Francis J. Burdon, Marcos Callisto, Cristina Canhoto, Krista A. Capps, Maria M. Castillo, Joanne Clapcott, Fanny Colas, Checo Checo Colón-Gaud, Julien Cornut, Verónica Crespo-Pérez, Wyatt F. Cross, Joseph M. Culp, Michael Danger, Olivier Dangles, Elvira De Eyto, Alison M. Derry, Veronica Díaz Villanueva, Michael M. Douglas, Arturo Elosegi, Andrea C. Encalada, Sally Entrekin, Rodrigo Espinosa, Diana Ethaiya, Verónica Ferreira, Carmen Ferriol, Kyla M. Flanagan, Tadeusz Fleituch, Jennifer J. Follstad Shah, André Frainer, Nikolai Friberg, Paul C. Frost, Erica A. Garcia, Liliana García Lago, Pavel Ernesto García Soto, Sudeep Ghate, Darren P. Giling, Alan Gilmer, José Franciso Gonçalves Jr., Rosario Karina Gonzales, Manuel A.S. Graça, Mike Grace, Hans-Peter Grossart, François Guérold, Vlad Gulis, Luiz U. Hepp, Scott Higgins, Takuo Hishi, Joseph Huddart, John Hudson, Samantha Imberger, Carlos Iñiguez-Armijos, Tomoya Iwata, David J. Janetski, Eleanor Jennings, Andrea E. Kirkwood, Aaron A. Koning, Sarian Kosten, Kevin A. Kuehn, Hjalmar Laudon, Peter R. Leavitt, Aurea L. Lemes Da Silva, Shawn G. Leroux, Carri J. Leroy, Peter J. Lisi, Richard Mackenzie, Amy M. Marcarelli, Frank O. Masese, Brendan G. Mckie, Adriana Oliveira Medeiros, Kristian Meissner, Marko Miliša, Shailendra Mishra, Yo Miyake, Ashley Moerke, Shorok Mombrikotb, Rob Mooney, Tim Moulton, Timo Muotka, Junjiro N. Negishi, Vinicius Neres-Lima, Mika L. Nieminen, Jorge Nimptsch, Jakub Ondruch, Riku Paavola, Isabel Pardo, Christopher J. Patrick, Edwin T.H.M. Peeters, Jesus Pozo, Catherine Pringle, Aaron Prussian, Estefania Quenta, Antonio Quesada, Brian Reid, John S. Richardson, Anna Rigosi, José Rincón, Geta Rîșnoveanu, Christopher T. Robinson, Lorena Rodríguez-Gallego, Todd V. Royer, James A. Rusak, Anna C. Santamans, Géza B. Selmeczy, Gelas Simiyu, Agnija Skuja, Jerzy Smykla, Kandikere R. Sridhar, Ryan Sponseller, Aaron Stoler, Christopher M. Swan, David Szlag, Franco Teixera-De Mello, Jonathan D. Tonkin, Sari Uusheimo, Allison M. Veach, Sirje Vilbaste, Lena B.M. Vought, Chiao-Ping Wang, Jackon R. Webster, Paul B. Wilson, Stefan Woelfl, Marguerite A. Xenopolous, Adam G. Yates, Chihiro Yoshimura, Catherine M. Yule, Yixin X. Zhang, Jacob A. Zwart

Faculty Publications

River ecosystems receive and process vast quantities of terrestrial organic carbon, the fate of which depends strongly on microbial activity. Variation in and controls of processing rates, however, are poorly characterized at the global scale. In response, we used a peer-sourced research network and a highly standardized carbon processing assay to conduct a global-scale field experiment in greater than 1000 river and riparian sites. We found that Earth’s biomes have distinct carbon processing signatures. Slow processing is evident across latitudes, whereas rapid rates are restricted to lower latitudes. Both the mean rate and variability decline with latitude, suggesting temperature constraints …

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Interaction Between Hydrogen Sulfide, Nitric Oxide, And Carbon Monoxide Pathways In The Bovine Isolated Retina, Madhura Kulkarni-Chitnis, Leah Mitchell-Bush, Remmington Belford, Jenaye Robinson, Catherine A. Opere, Sunny E. Ohia, Ya Fatou N. Mbye Jan 2019

Interaction Between Hydrogen Sulfide, Nitric Oxide, And Carbon Monoxide Pathways In The Bovine Isolated Retina, Madhura Kulkarni-Chitnis, Leah Mitchell-Bush, Remmington Belford, Jenaye Robinson, Catherine A. Opere, Sunny E. Ohia, Ya Fatou N. Mbye

Faculty Publications

Purpose: Nitric oxide (NO), carbon monoxide (CO) and hydrogen sulfide (H2S) are physiologically relevant gaseous neurotransmitters that are endogenously produced in mammalian tissues. In the present study, we investigated the possibility that NO and CO can regulate the endogenous levels of H2S in bovine isolated neural retina. Methods: Isolated bovine neural retina were homogenized and tissue homogenates were treated with a NO synthase inhibitor, NO donor, heme oxygenase-1 inhibitor, and/donor. H2S concentrations in bovine retinal homogenates were measured using a well-established colorimetric assay. Results: L-NAME (300 nM-500 μM) caused a concentration-dependent decrease in basal endogenous levels of H2S by 86.2%. …

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Energy Consumption Analysis Of A Duty Cycle Wireless Sensor Network Model, Yuhong Zhang, Wei Wayne Li Jan 2019

Energy Consumption Analysis Of A Duty Cycle Wireless Sensor Network Model, Yuhong Zhang, Wei Wayne Li

Faculty Publications

A novel model is developed and investigated for a duty-cycle wireless sensor network (WSN), where each sensor node can stay at one of four statuses (i.e., full-active phase, two semi-active phases each with different functions, and a sleep phase) to make the system more efficient. The explicit result of the joint probability for data packet numbers and the sensor phases is achieved by suitably constructing a multi-dimensional Markov process. Furthermore, various energy consumption measures, such as energy consumption per unit time in each of the three energy consumptions and energy consumption switching from one phase to another, are obtained. System …

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Haggadah And History, Fordham University Jan 2019

Haggadah And History, Fordham University

Faculty Publications

No abstract provided.

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"So Much For Darwin" An Analysis Of Stormfront Discussions On Race, Dianne Dentice Jan 2019

"So Much For Darwin" An Analysis Of Stormfront Discussions On Race, Dianne Dentice

Faculty Publications

Even though people who actively participate in the white nationalist movement appear to be a relatively small percentage of the global population, it appears that racist and anti-Semitic attitudes continue to inform a new generation of white nationalists, many of whom populate discussion forums on Stormfront, online since 1995 and billed as the first Internet site in the hate genre. Membership in extremist groups and support for sites like Stormfront embody specific attitudes about race, the importance of the existence of biological races, intellectual superiority of whites, and justification for these beliefs that is sometimes framed with a religious perspective …

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Effectiveness Of Plant Species For Removing Atmospheric Ammonia, Marife B. Anunciado, Sheryll B. Jerez, Hans Williams, Joey Bray, Dean W. Coble, Rena Saito Jan 2019

Effectiveness Of Plant Species For Removing Atmospheric Ammonia, Marife B. Anunciado, Sheryll B. Jerez, Hans Williams, Joey Bray, Dean W. Coble, Rena Saito

Faculty Publications

Six plant species of Yaupon, Eastern red cedar, American holly, Arizona cypress, Arborvitae and Roughleaf dogwood were utilized to determine their effectiveness in the removal of atmospheric ammonia. All species were exposed to three ammonia levels (1, 5 and 10 ppm) in an environmental chamber. Foliar ammonia content was quantified using an enzymatic technique. The effects of exposure to ammonia on the physiological responses (e.g. photosynthetic activity, stomatal conductance, and transpiration rate) of plants in ambient condition were also determined using an open design photosynthetic gas exchange system. Foliar ammonia content was significantly different among the six plant species (p<0.0001) with Eastern red cedar exhibiting the highest content. The physiological responses differed significantly depending on the plant species and the ammonia treatment level. The photosynthetic response of plants to the presence of ammonia was mixed. At low exposure level, all species except Arborvitae had decreased photosynthetic activity, reducing by as much as 44.5% for Yaupon. At the highest concentration, however, Yaupon’s photosynthetic activity improved by about 10%. Exposure to ammonia caused increased stomatal conductance and transpiration rate on American holly and Arizona cypress, making them more susceptible to water loss.

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Weed Control And Overstory Reduction Improve Survival And Growth Of Under‐Planted Oak And Hickory Seedlings, Luke B. Oliver, Jeremy Stovall, Chris E. Comer, Hans Williams, Matt E. Symmank Jan 2019

Weed Control And Overstory Reduction Improve Survival And Growth Of Under‐Planted Oak And Hickory Seedlings, Luke B. Oliver, Jeremy Stovall, Chris E. Comer, Hans Williams, Matt E. Symmank

Faculty Publications

Weed control and overstory reduction are important silvicultural treatments for improving survival and growth of under‐planted oak and hickory seedlings. Mast‐producing trees in the bottomland forests of the blackland prairie and Post Oak Savannah ecoregions of Texas have declined in abundance. Oaks and hickories have been replaced by more shade‐tolerant species, including green ash (Fraxinus pennsylvanica Marshall) and sugarberry (Celtis laevigata Willd.), which do not produce significant hard mast for priority wildlife species. A split‐plot experiment design was installed on three sites at Richland Creek Wildlife Management Area in Freestone County, Texas, studying the effects of canopy coverage …

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Distribution Of Contaminants In The Environment And Wildlife Habitat Use: A Case Study With Lead And Waterfowl On The Upper Texas Coast, Brian Kearns, Stephen Mcdowell, Jena A. Moon, Elizabeth Rigby, Warren C. Conway, David A. Haukos Jan 2019

Distribution Of Contaminants In The Environment And Wildlife Habitat Use: A Case Study With Lead And Waterfowl On The Upper Texas Coast, Brian Kearns, Stephen Mcdowell, Jena A. Moon, Elizabeth Rigby, Warren C. Conway, David A. Haukos

Faculty Publications

The magnitude and distribution of lead contamination remain unknown in wetland systems. Anthropogenic deposition of lead may be contributing to negative population-level effects in waterfowl and other organisms that depend on dynamic wetland habitats, particularly if they are unable to detect and differentiate levels of environmental contamination by lead. Detection of lead and behavioral response to elevated lead levels by waterfowl is poorly understood, but necessary to characterize the risk of lead-contaminated habitats. We measured the relationship between lead contamination of wetland soils and habitat use by mottled ducks (Anas fulvigula) on the Upper Texas Coast, USA. Mottled …

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Learning Altruism Through Stories And Action, Robert Atkinson, Adele Baruch Phd, Lillian Harris Jan 2019

Learning Altruism Through Stories And Action, Robert Atkinson, Adele Baruch Phd, Lillian Harris

Faculty Publications

In the course of our study on listening to stories of courage and moral choice, we noticed many examples of the way in which the stories appeared to function as a cognitive bridge, providing a vision of possibilities for caring action. We also observed that in order for these stories to promote identification with altruistic action for listeners, facilitative conditions are needed. The two facilitative conditions identified repeatedly by students and teachers were the sharing of the stories in a nurturing environment, where students felt emotionally safe, as well as an opportunity to practice helping behaviors, either inside or outside …

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Clown Eggs, David Fagundes, Aaron K. Perzanowski Jan 2019

Clown Eggs, David Fagundes, Aaron K. Perzanowski

Faculty Publications

Since 1946, many clowns have recorded their makeup by having it painted on eggs that are kept in a central registry in Wookey Hole, England. This tradition, which continues today, has been referred to alternately as a form of informal copyright registration and a means of protecting clowns’ property in their personae. This Article explores the Clown Egg Register and its sur- rounding practices from the perspective of law and social norms. In so doing, it makes several contributions. First, it contributes another chapter to the growing literature on the norms-based governance of intellectual property, showing how clowns—like comedians, roller …

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Associations Between Residual Feed Intake And Apparent Nutrient Digestibility, In Vitro Methane-Producing Activity, And Volatile Fatty Acid Concentrations In Growing Beef Cattle, Jocelyn R. Johnson, Gordon E. Carstens, Wimberly K. Krueger, Phillip A. Lancaster, Erin G. Brown, Luis O. Tedeschi, Robin C. Anderson, Kristen A. Johnson, Arieh Brosh Jan 2019

Associations Between Residual Feed Intake And Apparent Nutrient Digestibility, In Vitro Methane-Producing Activity, And Volatile Fatty Acid Concentrations In Growing Beef Cattle, Jocelyn R. Johnson, Gordon E. Carstens, Wimberly K. Krueger, Phillip A. Lancaster, Erin G. Brown, Luis O. Tedeschi, Robin C. Anderson, Kristen A. Johnson, Arieh Brosh

Faculty Publications

The objectives of this study were to examine the relationship between residual feed intake (RFI) and DM and nutrient digestibility, in vitro methane production, and volatile fatty acid (VFA) concentrations in growing beef cattle. Residual feed intake was measured in growing Santa Gertrudis steers (Study 1; n = 57; initial BW = 291.1 ± 33.8 kg) and Brangus heifers (Study 2; n = 468; initial BW = 271.4 ± 26.1 kg) fed a high-roughage-based diet (ME = 2.1 Mcal/kg DM) for 70 d in a Calan-gate feeding barn. Animals were ranked by RFI based on performance and feed intake measured …

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Race And Sport In The Florida Sun: The Rollins/Ohio Wesleyan Football Game Of 1947, Wenxian Zhang, Raja Rahim, Julian Chambliss Jan 2019

Race And Sport In The Florida Sun: The Rollins/Ohio Wesleyan Football Game Of 1947, Wenxian Zhang, Raja Rahim, Julian Chambliss

Faculty Publications

As the most popular sport in the United States, football occupies a central place in popular discourse. Since the early twentieth century, public engagement with football has been central to sport culture. Across the South, football provided a moment of common experience, and this was especially true of Rollins College. Being the oldest liberal arts institution in Florida, life at Rollins was linked to football for decades. Yet, as this comment suggested, the nature of the relationship could not be unaffected by the changing racial dynamic in the United States. As a small liberal arts college, the faculty and students …

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Review Of Anne Frank's Diary: The Graphic Adaptation, Carol A. Leibiger Jan 2019

Review Of Anne Frank's Diary: The Graphic Adaptation, Carol A. Leibiger

Faculty Publications

No abstract provided.

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Diversity And Shifts Of The Bacterial Community Associated With Baikal Sponge Mass Mortalities, Sergei Belikov, Natalia Belkova, Tatiana Butina, Lubov Chernogor, Alexandra Martynova-Van Kley, Armen Nalian, Colin Rorex, Igor Khanaev, Olga Maikova, Sergey Feranchuk Jan 2019

Diversity And Shifts Of The Bacterial Community Associated With Baikal Sponge Mass Mortalities, Sergei Belikov, Natalia Belkova, Tatiana Butina, Lubov Chernogor, Alexandra Martynova-Van Kley, Armen Nalian, Colin Rorex, Igor Khanaev, Olga Maikova, Sergey Feranchuk

Faculty Publications

The disease of freshwater sponges was first discovered in 2011, when pink samples were found in the Central Basin of Lake Baikal. Subsequently, the visible signs of the disease have changed, and now sponges appear with various symptoms of damage to the body, such as discoloration, tissue necrosis, the formation of brown patches and dirty-purple biofilms on some branches. These signs of the disease are accompanied by the mass death of sponges. We identified differences in microbiomes by sequencing 16S rRNA genes and found changes in the consortium of microorganisms of freshwater Baikal sponges. We found that the observed imbalance …

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Structural And Functional Determinants Of Rodent And Human Surfactant Protein A: A Synthesis Of Binding And Computational Data, Armen Nalian, Todd M. Umstead, Ching-Hui Yang, Patricia Silveyra, Neal J. Thomas, Joanna Floros, Francis X. Mccormack, Zissis C. Chroneos Jan 2019

Structural And Functional Determinants Of Rodent And Human Surfactant Protein A: A Synthesis Of Binding And Computational Data, Armen Nalian, Todd M. Umstead, Ching-Hui Yang, Patricia Silveyra, Neal J. Thomas, Joanna Floros, Francis X. Mccormack, Zissis C. Chroneos

Faculty Publications

Surfactant protein A (SP-A) provides surfactant stability, first line host defense, and lung homeostasis by binding surfactant phospholipids, pathogens, alveolar macrophages (AMs), and epithelial cells. Non-primates express one SP-A protein whereas humans express two: SP-A1 and SP-A2 with core intra- and inter-species differences in the collagen-like domain. Here, we used macrophages and solid phase binding assays to discern structural correlates of rat (r) and human (h) SP-A function. Binding assays using recombinant rSP-A expressed in insect cells showed that lack of proline hydroxylation, truncations of amino-terminal oligomerization domains, and site-directed serine (S) or alanine (A) mutagenesis of cysteine 6 (C6S), …

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Arachidin-1 And Arachidin-3 Modulation Of Rotavirus-Infected Ma104 Cells, Caleb M. Witcher, Rebekah Napier-Jameson, Hannah N. Lockwood, Macie N. Mattila, Stormey B. Wisdom, Luanna L. Saade Ferreira, Josephine Taylor, Beatrice Clack, Fabricio Medina-Bolivar, Judith M. Ball, Rebecca D. Parr Jan 2019

Arachidin-1 And Arachidin-3 Modulation Of Rotavirus-Infected Ma104 Cells, Caleb M. Witcher, Rebekah Napier-Jameson, Hannah N. Lockwood, Macie N. Mattila, Stormey B. Wisdom, Luanna L. Saade Ferreira, Josephine Taylor, Beatrice Clack, Fabricio Medina-Bolivar, Judith M. Ball, Rebecca D. Parr

Faculty Publications

Rotavirus (RV) causes severe life-threatening diarrhea in young children and immunocompromised individuals. There are several licensed attenuated vaccines for young children, but there are no vaccines or antiviral therapeutics for immunocompromised patients of any age. Previously, our laboratory demonstrated that arachidin 1 (A1) and arachidin 3 (A3) decreases the number of infectious simian RV particles and RV non-structural protein 4 (NSP4) in a human intestinal cell line which suggests effects on RV replication. This study examined the effects of the arachidins on the human RV (Wa)-infected African green monkey kidney cell line, MA104. The addition of either A1 or A3 …

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Conflicts Of Interest And Law-Firm Structure, Cassandra Burke Robertson Jan 2019

Conflicts Of Interest And Law-Firm Structure, Cassandra Burke Robertson

Faculty Publications

Business and law are increasingly practiced on a transnational scale, and law firms are adopting new business structures in order to compete on this global playing field. Over the last decade, global law firms have merged into so-called “mega-brands” or “mega-firms”—that is, associations of national or regional law firms that join together under a single brand worldwide. For law firms, the most common mega-firm structure has been the Swiss verein, though the English “Company Limited by Guarantee” structure is growing in popularity as well, as is the similar “European Economic Interest Grouping.” All of these structures allow related entities to …

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Principal Component Analysis Of The Magnetic Transition In The Three-Dimensional Fermi-Hubbard Model, Ehsan Khatami Jan 2019

Principal Component Analysis Of The Magnetic Transition In The Three-Dimensional Fermi-Hubbard Model, Ehsan Khatami

Faculty Publications

Machine learning techniques have been widely used in the study of strongly correlated systems in recent years. Here, we review some applications to classical and quantum many-body systems and present results from an unsupervised machine learning technique, the principal component analysis, employed to identify the finite-temperature phase transition of the three-dimensional Fermi-Hubbard model to the antiferromagnetically ordered state. We find that this linear method can capture the phase transition as well as other more complicated and nonlinear counterparts.

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Move It Or Lose It: Interspecific Variation In Risk Response Of Pond-Breeding Anurans, Philip Matich, Christopher M. Schalk Jan 2019

Move It Or Lose It: Interspecific Variation In Risk Response Of Pond-Breeding Anurans, Philip Matich, Christopher M. Schalk

Faculty Publications

Changes in behavior are often the proximate response of animals to human disturbance, with variability in tolerance levels leading some species to exhibit striking shifts in life history, fitness, and/or survival. Thus, elucidating the effects of disturbance on animal behavior, and how this varies among taxonomically similar species with inherently different behaviors and life histories is of value for management and conservation. We evaluated the risk response of three anuran species—southern leopard frog (Lithobates sphenocephalus), Blanchard’s cricket frog (Acris blanchardi), and green tree frog (Hyla cinerea)—to determine how differences in microhabitat use (arboreal vs …

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Correlates Of Snake Entanglement In Erosion Control Blankets, Sarah E. Ebert, Kasey L. Jobe, Christopher M. Schalk, Daniel Saenz, Cory K. Adams, Christopher E. Comer Jan 2019

Correlates Of Snake Entanglement In Erosion Control Blankets, Sarah E. Ebert, Kasey L. Jobe, Christopher M. Schalk, Daniel Saenz, Cory K. Adams, Christopher E. Comer

Faculty Publications

In road construction projects across the United States, erosion control methods (e.g., erosion control blankets [ECBs]), are mandated to stimulate seedbed regeneration and prevent soil loss. Previous reports have suggested that snakes are vulnerable to entanglement in ECBs. We conducted a literature review, field surveys, and an entanglement experiment to examine what factors increase a snake’s risk of ECB entanglement. Our literature review produced reports of 175 reptiles entangled in mesh products, 89.1% of which were snakes, with 43.6% of snake entanglements occurring in erosion control products. During our field surveys, we found 10 entangled snakes (n = 2 alive; …

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How Does Perceived Destination Social Responsibility Impact Revisit Intentions: The Mediating Roles Of Destination Preference And Relationship Quality, Lujun Su, Yinghua Huang Jan 2019

How Does Perceived Destination Social Responsibility Impact Revisit Intentions: The Mediating Roles Of Destination Preference And Relationship Quality, Lujun Su, Yinghua Huang

Faculty Publications

This study applied the relationship quality theory to examine how destination social responsibility (DSR) impacts revisit intentions through the mediation of destination preference and relationship quality (i.e., tourist satisfaction and identification). An integrated model was proposed and tested by using survey data from an urban tourism attraction in China. The findings indicate that DSR positively impacts destination preference and tourist satisfaction, but it does not have a significant influence on tourist-destination identification. Destination preference directly affects tourist satisfaction and tourist-destination identification, which in turn positively influences revisit intentions. This study offered theoretical and practical contributions to the research of destination …

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Defining Choices Redefined: Heroic Life Narratives Of Taiwanese Buddhist Monastics, Hillary Crane Jan 2019

Defining Choices Redefined: Heroic Life Narratives Of Taiwanese Buddhist Monastics, Hillary Crane

Faculty Publications

The Taiwanese Buddhist monastics in this study confront negative stereotypes that dominate within their wider societal context, and they challenge these stereotypes by positing counter-narratives. After exploring the monastics’ interest in proselytizing both to me and to a wider audience as a context that influences the interview encounter, this chapter focuses on the monastics’ response to negative stereotypes and their endeavors to craft a new, positive image of monastics. I argue that they employ the heroic trope of the da zhangfu (大丈夫, ‘great man’) to reconceive as heroic the life choices they have made that wider Taiwanese society characterizes as …

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Crossed Tracks: Mesolimulus, Archaeopteryx, And The Nature Of Fossils, Leonard Finkelman Jan 2019

Crossed Tracks: Mesolimulus, Archaeopteryx, And The Nature Of Fossils, Leonard Finkelman

Faculty Publications

Organisms leave a variety of traces in the fossil record. Among these traces, vertebrate and invertebrate paleontologists conventionally recognize a distinction between the remains of an organism’s phenotype (body fossils) and the remains of an organism’s life activities (trace fossils). The same convention recognizes body fossils as biological structures and trace fossils as geological objects. This convention explains some curious practices in the classification, as with the distinction between taxa for trace fossils and for tracemakers. I consider the distinction between “parallel taxonomies,” or parataxonomies, which privileges some kinds of fossil taxa as “natural” and others as “artificial.” The motivations …

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Betting & Hierarchy In Paleontology, Leonard Finkelman Jan 2019

Betting & Hierarchy In Paleontology, Leonard Finkelman

Faculty Publications

In his Rock, Bone, and Ruin: An Optimist’s Guide to the Historical Sciences, Adrian Currie argues that historical scientists should be optimistic about success in reconstructing the past on the basis of future research. This optimism follows in part from examples of success in paleontology. I argue that paleontologists’ success in these cases is underwritten by the hierarchical nature of biological information: extinct organisms have extant analogues at various levels of taxonomic, ecological, and physiological hierarchies, and paleontologists are adept at exploiting analogies within one informational hierarchy to infer information in another. On this account, fossils serve the role …

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Making Herstory: Cherokee Women's Stickball, Natalie M. Welch, Jessica Siegele, Zachary T. Smith, Robin Hardin Jan 2019

Making Herstory: Cherokee Women's Stickball, Natalie M. Welch, Jessica Siegele, Zachary T. Smith, Robin Hardin

Faculty Publications

Cherokee stickball amongst the Eastern Band of Cherokee Indians is a sporting tradition that precedes written records. Historical and academic texts have focused on men’s participation in the sport. However, Cherokee women participated in their own stickball games as recent as a decade ago, and stories exist of women playing stickball in the late nineteenth century. Many in the community believe stickball should not be played by women and doubt evidence of women playing historically. Researchers sought to understand the intersectionality of gender and ethnic identity for female stickball players who took the field to play stickball at the turn …

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Effects Of Shoal Margin Collapses On The Morphodynamics Of A Sandy Estuary, M. R. Hiatt Jan 2019

Effects Of Shoal Margin Collapses On The Morphodynamics Of A Sandy Estuary, M. R. Hiatt

Faculty Publications

Shoal margin collapses of several million cubic meters have occurred in the Western Scheldt estuary, the Netherlands, on average five times a year over the last decades. While these collapses involve significant volumes of material, their effect on the channel-shoal morphology is unknown. We hypothesize that collapses dynamicize the channel-shoal interactions, which could impact the ecological functioning, flood safety, and navigation in the estuary. The objective is to investigate how locations, probability, type, and volume of shoal margin collapse affect the channel-shoal dynamics. We implemented an empirically validated parameterization for shoal margin collapses and tested its effect on simulated estuary …

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Net Land Gain Or Loss For Two Mississippi River Diversions: Caernarvon And Davis Pond, R. Eugene Turner, M Layne, Y Mo, E M. Swenson Jan 2019

Net Land Gain Or Loss For Two Mississippi River Diversions: Caernarvon And Davis Pond, R. Eugene Turner, M Layne, Y Mo, E M. Swenson

Faculty Publications

Coastal wetland restoration can be complex and expensive, so knowing long-term consequences makes it important to inform decisions about if, when, and where to conduct restoration. We determined temporal changes in land gain and loss in receiving basins and adjacent reference areas for two diversions of the Mississippi River in south Louisiana (Davis Pond and Caernarvon initiated in 1991 and 2002, respectively). Water from both diversions went into receiving basins with vegetated areas as did the adjoining reference areas. The results from two different types of satellite imagery analyses demonstrate a net land loss after diversions began. The results were …

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