Digital Commons Network^™

International Reverse Transfer Students: A Critical Analysis Based On Field, Habitus, And Social And Cultural Capital, Yu “April” Chen, Ran Li, Linda Serra Hagedorn

Faculty Publications

Objective: International reverse transfer students are international students who begin their postsecondary journey at a four-year institution but subsequently transfer to a community college. In this qualitative study, we examine the lived experiences of international reverse transfers to understand the reasons for reverse-transfer and to understand the students’ learning experiences. Methods: Using a phenomenological approach, we recruited 10 international reverse transfer students attending one four-year university or one of the two community colleges. We conducted individual interviews with all participants and analyzed transcript data through Bourdieu’s sociological theory of field, habitus, and social and cultural capital. Results: We identified three …

Measuring The Resilience Of Criminogenic Ecosystems To Global Disruption: A Case-Study Of Covid-19 In China, Hervé Borrion, Justin Kurland, Nick Tilley, Peng Chen

Faculty Publications

Copyright: © 2020 Borrion et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This paper uses resilience as a lens through which to analyse disasters and other major threats to patterns of criminal behaviour. A set of indicators and mathematical models are introduced that aim to quantitatively describe changes in crime levels in comparison to what could otherwise be expected, and what might be expected by way of adaptation and subsequent resumption of …

Oil-Producing Metabolons Containing Dgat1 Use Separate Substrate Pools From Those Containing Dgat2 Or Pdat, Anushobha Regmi, Jay Shockey, Hari Kiran Kotapati, Philip D. Bates

Faculty Publications

© 2020 American Society of Plant Biologists. All rights reserved. Seed triacylglycerol (TAG) biosynthesis involves a metabolic network containing multiple different diacylglycerol (DAG) and acyl donor substrate pools. This network of pathways overlaps with those for essential membrane lipid synthesis and utilizes multiple different classes of TAG biosynthetic enzymes. Acyl flux through this network ultimately dictates the final oil fatty acid composition. Most strategies to alter seed oil composition involve the overexpression of lipid biosynthetic enzymes, but how these enzymes are assembled into metabolons and which substrate pools are used by each is still not well understood. To understand the …

Expanding The Reach Of Progressive Prosecution, Jeffrey Bellin

Faculty Publications

No abstract provided.

The Seventh-Day Adventist Identity - Who Are We As A Community Of Faith?, Jiri Moskala

Faculty Publications

No abstract provided.

Distorted Drug Patents, Erika Lietzan

Faculty Publications

Drug patents are distorted. Unlike most other inventors, drug inventors must complete years of testing to the government’s specifications and seek government approval to commercialize their inventions. All the while, the patent term runs. When a drug inventor finally launches a medicine that embodies the invention, only a fraction of the patent life remains. And yet, conventional wisdom holds — and empirical studies show — that patent life is essential to innovation in the pharmaceutical industry, perhaps more so than any other inventive industry. Congress tried to do something about this in 1984, authorizing the Patent and Trademark Office to …

Antitrust Regulation And The Federal-State Balance: Restoring The Original Design, Alan J. Meese

Faculty Publications

The U.S. Constitution divides authority over commerce between states and the national government. Passed in 1890, the Sherman Act (“the Act”) reflects this allocation of power, reaching only those harmful agreements that are “in restraint of... commerce among the several States.” This Article contends that the Supreme Court erred when it radically altered the balance between state and national power over trade restraints in 1948, abruptly abandoning decades of precedent recognizing exclusive state authority over most intrastate restraints. This revised construction of the Act contravened the statute’s apparent meaning, unduly expanded the reach of federal antitrust regulation, and undermined the …

The Indispensable God's Presence: Toward The Theology Of God's Face, Jiri Moskala

Faculty Publications

No abstract provided.

Covid-19 And The Black Death: Nutrition, Frailty, Inequity, And Mortality, Katherine D. Van Schaik, Sharon Dewitte

Faculty Publications

Introduction: COVID-19 has challenged governments, healthcare systems, and individuals, drawing attention to the limits of modern technology and the extent of social inequity. Such challenges have directed attention to historical epidemics as repositories of data that could contribute to effective public health strategies and prognostic modeling. In light of the well-established correlation between frailty and mortality from COVID-19, this paper investigates the relationship between frailty, inequity, and mortality in the setting of the Black Death of 1346 – 1353, in order to identify trends over time in populations at the greatest risk of mortality during pandemics.

Methods: A comparative review …

177Lu-Labeled Eu-Doped Mesoporous Sio2Nanoparticles As A Theranostic Radiopharmaceutical For Colorectal Cancer, Rodrigo Da Silva Viana, Luciana Amaral De Mescana Costa, Ashlyn C. Harmon, Manoel Adrião Gomes Filho, Eduardo H.L. Falcão, Maria G.H. Vicente, Severino A. Junior, J. Michael Mathis

Faculty Publications

Copyright © 2020 American Chemical Society. Colorectal cancer is one of the most significant types of cancer, ranking second in the world's mortality cases. As colorectal cancer is often diagnosed at a late stage of disease progression, effective treatments are necessary. Therefore, radiotherapy has become a fundamental approach in the treatment of colorectal cancer, especially those based on the use of 177Lu. A potential approach to meet this challenge is the use of nanotechnology through the development of radionuclide-based nanomaterials. In this work, we investigated a SiO2-derived class of nanomaterials formed by the insertion of the coordination complex, based on …

Beyond Books 2: Cataloging Archival Materials, Allie Mccormack, Rebecca A. Wiederhold, Nicole Lewis, Becky Skeen

Faculty Publications

View the video presentation in two parts at the following links:

Part 1 https://youtu.be/EQEhVpmfOBc

Part 2 https://youtu.be/XIAMdPYspFo

Archival materials can often be found in cultural heritage organizations that do not have trained special collections catalogers on staff. In this workshop, participants will learn how to catalog manuscripts, photographs, and audiovisual materials so they can be discovered in online catalogs and databases. Both item and collection-level cataloging will be discussed and participants will learn when and how to apply metadata standards like RDA and DACS. Time for hands-on practice will be included.

Low Aflatoxin Levels In Aspergillus Flavus-Resistant Maize Are Correlated With Increased Corn Earworm Damage And Enhanced Seed Fumonisin, Subbaiah Chalivendra, Fangneng Huang, Mark Busman, W. Paul Williams, Jong Hyun Ham

Faculty Publications

Preharvest mycotoxin contamination of field-grown crops is influenced not only by the host genotype, but also by inoculum load, insect pressure and their confounding interactions with seasonal weather. In two different field trials, we observed a preference in the natural infestation of corn earworm (CEW; Helicoverpa zea Boddie) to specific maize (Zea mays L.) genotypes and investigated this observation. The field trials involved four maize lines with contrasting levels of resistance to Aspergillus flavus. The resistant lines had 7 to 14-fold greater infested ears than the susceptible lines. Seed aflatoxin B1 (AF) levels, in mock- and A. flavus-inoculated ears were …

Effect Of Oxidation Level On The Interfacial Water At The Graphene Oxide-Water Interface: From Spectroscopic Signatures To Hydrogen-Bonding Environment, Rolf David, Aashish Tuladhar, Le Zhang, Christopher Arges, Revati Kumar

Faculty Publications

Copyright © 2020 American Chemical Society. The interfacial region of the graphene oxide (GO)-water system is nonhomogenous due to the presence of two distinct domains: an oxygen-rich surface and a graphene-like region. The experimental vibrational sum-frequency generation (vSFG) spectra are distinctly different for the fully oxidized GO-water interface as compared to the reduced GO-water case. Computational investigations using ab initio molecular dynamics were performed to determine the molecular origins of the different spectroscopic features. The simulations were first validated by comparing the simulated vSFG spectra to those from the experiment, and the contributions to the spectra from different hydrogen bonding …

Effect Of Oxidation Level On The Interfacial Water At The Graphene Oxide-Water Interface: From Spectroscopic Signatures To Hydrogen-Bonding Environment, Rolf David, Aashish Tuladhar, Le Zhang, Christopher Arges, Revati Kumar

Faculty Publications

The interfacial region of the graphene oxide (GO)-water system is nonhomogenous due to the presence of two distinct domains: an oxygen-rich surface and a graphene-like region. The experimental vibrational sum-frequency generation (vSFG) spectra are distinctly different for the fully oxidized GO-water interface as compared to the reduced GO-water case. Computational investigations using ab initio molecular dynamics were performed to determine the molecular origins of the different spectroscopic features. The simulations were first validated by comparing the simulated vSFG spectra to those from the experiment, and the contributions to the spectra from different hydrogen bonding environments and interfacial water orientations were …

Zika Virus Infection Causes Widespread Damage To The Inner Ear, Kathleen T. Yee, Biswas Neupane, Fengwei Bai, Douglas E. Vetter

Faculty Publications

Zika virus (ZIKV) has been recently recognized as a causative agent of newborn microcephaly, as well as other neurological consequences. A less well recognized comorbidity of prenatal ZIKV infection is hearing loss, but cases of hearing impairment following adult ZIKV infection have also been recognized. Diminished hearing following prenatal ZIKV infection in a mouse model has been reported, but no cellular consequences were observed. We examined the effects of ZIKV infection on inner ear cellular integrity and expression levels of various proteins important for cochlear function in type I interferon receptor null (Ifnar1^−/−) mice following infection at …

A Reenvisioned Agricultural System In Thailand: The Growth In Human Capital Experienced By Agriculturalists After Adoption Of The Sufficiency Economic Philosophy, Alexis C. Agard, Richie Roberts

Faculty Publications

No abstract provided.

Redox-Sensitive Nanocomplex For Targeted Delivery Of Melittin, Bei Cheng, Peisheng Xu

Faculty Publications

Although peptide therapeutics have been explored for decades, the successful delivery of potent peptides in vitro and in vivo remains challenging due to the poor stability, low cell permeability, and off-target effects. We developed a redox sensitive polymer-based nanocomplex which can efficiently and stably deliver the peptide drug melittin for cancer therapy. The nanocomplex selectively targets cancer cells through lactobionic acid mediated endocytosis and releases melittin intracellularly upon the trigger of elevated redox potential. In vivo study proved that the targeted nanocomplex shows excellent potency in inhibiting tumor growth in a xenograft colon cancer mouse model. Thus, the polymer/melittin nanocomplexes …

Obesity Worsens Gulf War Illness Symptom Persistence Pathology By Linking Altered Gut Microbiome Species To Long-Term Gastrointestinal, Hepatic, And Neuronal Inflammation In A Mouse Model, Dipro Bose, Punnag Saha, Ayan Mondal, Brian Fanelli, Ratanesh K. Seth, Patricia Janulewicz, Kimberly Sullivan, Stephen Lasley, Ronnie Horner, Rita R. Colwell, Ashok K. Shetty, Nancy Klimas, Saurabh Chatterjee

Faculty Publications

Persistence of Gulf War illness (GWI) pathology among deployed veterans is a clinical challenge even after almost three decades. Recent studies show a higher prevalence of obesity and metabolic disturbances among Gulf War veterans primarily due to the existence of post-traumatic stress disorder (PTSD), chronic fatigue, sedentary lifestyle, and consumption of a high-carbohydrate/high-fat diet. We test the hypothesis that obesity from a Western-style diet alters host gut microbial species and worsens gastrointestinal and neuroinflammatory symptom persistence. We used a 5 month Western diet feeding in mice that received prior Gulf War (GW) chemical exposure to mimic the home phase obese …

Machine Intelligence For Nerve Conduit Design And Production, Caleb E. Stewart, Chin Fung Kelvin Kan, Brody R. Stewart, Henry W. Sanicola Iii, Jangwook P. Jung, Olawale A. R. Sulaiman, Dadong Wang

Faculty Publications

Nerve guidance conduits (NGCs) have emerged from recent advances within tissue engineering as a promising alternative to autografts for peripheral nerve repair. NGCs are tubular structures with engineered biomaterials, which guide axonal regeneration from the injured proximal nerve to the distal stump. NGC design can synergistically combine multiple properties to enhance proliferation of stem and neuronal cells, improve nerve migration, attenuate inflammation and reduce scar tissue formation. The aim of most laboratories fabricating NGCs is the development of an automated process that incorporates patient-specific features and complex tissue blueprints (e.g. neurovascular conduit) that serve as the basis for more complicated …

Cyclic Topology Enhancing Structural Ordering And Stability Of Comb-Shaped Polypeptoid Thin Films Against Melt-Induced Dewetting, Naisheng Jiang, Jianxia Chen, Tianyi Yu, Albert Chao, Liying Kang, Ying Wu, Kangmin Niu, Ruipeng Li, Masafumi Fukuto, Donghui Zhang

Faculty Publications

Copyright © 2020 American Chemical Society. We investigated the effect of cyclic chain topology on the molecular ordering and thermal stability of comb-shaped polypeptoid thin films on silicon (Si) substrates. Cyclic and linear poly(N-decylglycine) (PNDG) bearing long n-decyl side chains were synthesized by ring-opening polymerization of N-decylglycine-derived N-carboxyanhydrides. When the spin-coated thin films were subjected to thermal annealing at temperatures above the melting temperature (T > Tm), the cyclic PNDG films exhibited significantly enhanced stability against melt-induced dewetting than the linear counterparts (l-PNDG). When recrystallized at temperatures below the crystallization temperature (T < Tc), the homogeneous c-PNDG films exhibit enhanced crystalline ordering relative to the macroscopically dewetted l-PNDG films. Both cyclic and linear PNDG molecules adopt cis-amide conformations in the crystalline film, which transition into trans-amide conformations upon melting. A top-down solvent leaching treatment of both l/c-PNDG films revealed the formation of an irreversibly physisorbed monolayer with similar thickness (ca. 3 nm) on the Si substrate. The physisorbed monolayers are more disordered relative to the respective thicker crystalline films for both cyclic and linear PNDGs. Upon heating above Tm, the adsorbed c-PNDG chains adopt trans-amide backbone conformation identical with the free c-PNDG molecules in the molten film. By contrast, the backbone conformations of l-PNDG chains in the adsorbed layers are notably different from those of the free chains in the molten film. We postulate that the conformational disparity between the chains in the physically adsorbed layers versus the free chains in the molten film is an important factor to account for the difference in the thermal stability of PNDG thin films. These findings highlight the use of cyclic chain topology to suppress the melt-induced dewetting in polymer thin films.

A Glance Of P53 Functions In Brain Development, Neural Stem Cells, And Brain Cancer, Yuqing Xiong, Yun Zhang, Shunbin Xiong, Abie E. Williams-Villalobo

Faculty Publications

p53 is one of the most intensively studied tumor suppressors. It transcriptionally regulates a broad range of genes to modulate a series of cellular events, including DNA damage repair, cell cycle arrest, senescence, apoptosis, ferroptosis, autophagy, and metabolic remodeling, which are fundamental for both development and cancer. This review discusses the role of p53 in brain development, neural stem cell regulation and the mechanisms of inactivating p53 in gliomas. p53 null or p53 mutant mice show female biased exencephaly, potentially due to X chromosome inactivation failure and/or hormone-related gene expression. Oxidative cellular status, increased PI3K/Akt signaling, elevated ID1, and metabolism …

N-Element Beam Antennas System Design For Wireless Sensor Node Using Semi-Markov Decision Process With Variable Sojourn Time, Abayomi Ajofoyinbo, David O. Olowokere, Oye Ibidapo-Obe

Faculty Publications

Abstract-The paper presents N-element switchable beam antennas (BAs) system design for Wireless Sensor Node (WSN), in which the operation of the BAs was characterized by semi-Markov Decision Process (SMDP) with variable sojourn time. A matrix-based switching methodology was introduced for selecting an operational BA, based on the received signal power by each BA. Optimal analysis was carried-out to obtain optimal results in terms of the maximum total of sum of discounted reward in current states. Also developed in the study is the methodology for switching a BA from non-operational to operational state and vice-versa. The effectiveness of this switchable BAs …

Evaluating The Potential Of Drone Swarms In Nonverbal Hri Communication, Kasper Grispino, Damian Lyons, Truong-Huy Nguyen

Faculty Publications

Human-to-human communications are enriched with affects and emotions, conveyed, and perceived through both verbal and nonverbal communication. It is our thesis that drone swarms can be used to communicate information enriched with effects via nonverbal channels: guiding, generally interacting with, or warning a human audience via their pattern of motions or behavior. And furthermore that this approach has unique advantages such as flexibility and mobility over other forms of user interface. In this paper, we present a user study to understand how human participants perceived and interpreted swarm behaviors of micro-drone Crazyflie quadcopters flying three different flight formations to bridge …

Tropical Cyclone Landfall Frequency And Large-Scale Environmental Impacts Along Karstic Coastal Regions (Yucatan Peninsula, Mexico), Victor H. Rivera-Monroy, Luis M. Farfan, Luis Brito-Castillo, Jorge Cortes-Ramos, Eduardo Gonzalez-Rodriguez, Eurico D'Sa, Jorge I. Euan-Avila

Faculty Publications

Tropical cyclones (TCs) are natural systems that develop over ocean basins and are key components of the atmospheric activity during the warm season. However, there are still knowledge gaps about the combined positive and negative TC impacts on the structure and function of coastal socio-ecosystems. Using remote sensing tools, we analyzed the frequency, trajectory, and intensity of 1894 TCs from 1851-2019 to identify vulnerable "hotspots" across the Yucatan Peninsula (YP), Mexico. A total of 151 events hit the YP, with 96% of landings on the eastern coast. We focused on three major hurricanes (Emily and Wilma, 2005; Dean, 2007) and …

No, You Go First: Phenotype And Social Context Affect House Sparrow Neophobia: Social Learning Can Persist In Sparrows, T. R. Kelly, M. G. Kimball, K. R. Stansberry, C. R. Lattin

Faculty Publications

© 2020 The Author(s). Novel object trials are commonly used to assess aversion to novelty (neophobia), and previous work has shown neophobia can be influenced by the social environment, but whether the altered behaviour persists afterwards (social learning) is largely unknown in wild animals. We assessed house sparrow (Passer domesticus) novel object responses before, during and after being paired with a conspecific of either similar or different behavioural phenotype. During paired trials, animals housed with a similar or more neophobic partner demonstrated an increased aversion to novel objects. This change did not persist a week after unpairing, but neophobia decreased …

Mechanisms Of Artemisia Scoparia’S Anti-Inflammatory Activity In Cultured Adipocytes, Macrophages, And Pancreatic Β-Cells, Anik Boudreau, Susan J. Burke, J. Jason Collier, Allison J. Richard, David M. Ribnicky, Jacqueline M. Stephens

Faculty Publications

© 2020 The Obesity Society Objective: An ethanolic extract of Artemisia scoparia (SCO) improves adipose tissue function and reduces negative metabolic consequences of high-fat feeding. A. scoparia has a long history of medicinal use across Asia and has anti-inflammatory effects in various cell types and disease models. The objective of the current study was to investigate SCO’s effects on inflammation in cells relevant to metabolic health. Methods: Inflammatory responses were assayed in cultured adipocytes, macrophages, and insulinoma cells by quantitative polymerase chain reaction, immunoblotting, and NF-κB reporter assays. Results: In tumor necrosis factor α–treated adipocytes, SCO mitigated ERK and NF-κB …

References To Children's Stories And Fairy Tales In Judicial Opinions And Written Advocacy, Douglas E. Abrams

Faculty Publications

Jones v. State is typical of recent state and federal court decisions that have spiced substantive or procedural points with references to classic children’s stories or classic fairy tales. These literary resources have won places in American popular culture and are likely generally familiar to readers, especially when (as in Jones) the court provides any necessary context explaining the resource’s relevance to the decision.

In previous Journal of The Missouri Bar articles, I have written about judges’ invocation of an array of influential cultural markers that are generally familiar to Americans. These articles explored written opinions that accompanied substantive or …

Complement In Reproductive White Adipose Tissue Characterizes The Obese Preeclamptic-Like Bph/5 Mouse Prior To And During Pregnancy, Kelsey N. Olson, Dorien Reijnders, Viviane C.L. Gomes, R. Caitlin Hebert, Chin Chi Liu, Jacqueline M. Stephens, Leanne M. Redman, Nataki C. Douglas, Jennifer L. Sones

Faculty Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Preeclampsia (PE) is a serious hypertensive disorder of pregnancy characterized by abnormal placental development with an unknown etiology. To better understand which women will develop PE, a number of maternal risk factors have been identified, including obesity. Visceral white adipose tissue (WAT) contains inflammatory mediators that may contribute to PE. To explore this, we utilized the blood pressure high (BPH)/5 mouse model of superimposed PE that spontaneously recapitulates the maternal PE syndrome. We hypothesized that BPH/5 visceralWAT adjacent to the female reproductive tract (reproductiveWAT) is a source of complement factors that …

Fire As A Fundamental Ecological Process: Research Advances And Frontiers, Kendra K. Mclauchlan, Philip E. Higuera, Jessica Miesel, Brendan M. Rogers, Jennifer Schweitzer, Jacquelyn K. Shuman, Alan J. Tepley, J. Morgan Varner, Thomas T. Veblen, Solny A. Adalsteinsson, Jennifer K. Balch, Patrick Baker, Enric Batllori, Erica Bigio, Paulo Brando, Megan Cattau, Melissa L. Chipman, Janice Coen, Raelene Crandall, Lori Daniels, Neal Enright, Wendy S. Gross, Brian J. Harvey, Jeff A. Hatten, Sharon Hermann, Rebecca E. Hewitt, Leda N. Kobziar, Jennifer B. Landesmann, Michael M. Loranty, S. Yoshi Maezumi, Linda Mearns, Max Moritz, Jonathan A. Myers

Faculty Publications

© 2020 The Authors. Journal of Ecology published by John Wiley & Sons Ltd on behalf of British Ecological Society Fire is a powerful ecological and evolutionary force that regulates organismal traits, population sizes, species interactions, community composition, carbon and nutrient cycling and ecosystem function. It also presents a rapidly growing societal challenge, due to both increasingly destructive wildfires and fire exclusion in fire-dependent ecosystems. As an ecological process, fire integrates complex feedbacks among biological, social and geophysical processes, requiring coordination across several fields and scales of study. Here, we describe the diversity of ways in which fire operates as …

The Influence Of Stochasticity, Landscape Structure And Species Traits On Abundant–Centre Relationships, Tad A. Dallas, Luca Santini

Faculty Publications

© 2020 The Authors. Ecography published by John Wiley & Sons Ltd on behalf of Nordic Society Oikos Species have been commonly hypothesized to have high population densities in geographic areas which correspond to either the centre of the species geographic range or climatic niche (abundant–centre hypothesis). However, there is mixed empirical support for this relationship, and little theoretical underpinning. We simulate a species spreading across a set of replicated artificial landscapes to examine the expected level of support for abundant–centre relationships in geographic and niche space. Species niche constraints were modeled as a single axis which was related directly …