Digital Commons Network^™

Assessment Of Multiple-Form Structure Designs Of Multistage Testing Using Irt, Hanan M. Alghamdi

Electronic Theses and Dissertations

The current study investigated multistage testing (MST) as an alternative to classical linear testing (CLT) for the General Aptitude Test (GAT). The aim was to assess the effects of two assembly methods (narrow vs. wide range—NR vs. WR), two routing methods (Defined Population Intervals—DPI— and the Approximate Maximum Information method—AMI), and two panel structures (two-stage and three-stage) on precision of ability estimates and accuracy of classification for both sections of the GAT (Verbal and Mathematics). Thus, eight conditions were examined and compared: 2 (assembly conditions) * 2 (panel structures) * 2 (routing methods).

The dataset that included a sample of …

Developing A Femtosecond Stimulated Raman Spectroscopy Experiment For Solid State Materials, Daniel Hammerland

Electronic Theses and Dissertations

Femtosecond Stimulated Raman Spectroscopy (FSRS) is a ultrafast spectroscopy technique first implemented by chemists to understand isomerization and other ultrafast molecular morphology changes by resolving vibrational dynamics[1, 2, 3]. FSRS has an unparalleled temporal and spectral resolution [4, 1, 5, 6] that arises as a result of a clever combination of picosecond and femtosecond pulses. However, despite this capability, FSRS has yet to be applied to modern materials in condensed matter physics. This thesis explores the design and implementation of FSRS to study two-dimensional materials in order to measure their quantum confined vibrational dynamics on utlrafast time scales.

A Bi-Encoder Lstm Model For Learning Unstructured Dialogs, Diwanshu Shekhar

Electronic Theses and Dissertations

Creating a data-driven model that is trained on a large dataset of unstructured dialogs is a crucial step in developing a Retrieval-based Chatbot systems. This thesis presents a Long Short Term Memory (LSTM) based Recurrent Neural Network architecture that learns unstructured multi-turn dialogs and provides implementation results on the task of selecting the best response from a collection of given responses. Ubuntu Dialog Corpus Version 2 (UDCv2) was used as the corpus for training. Ryan et al. (2015) explored learning models such as TF-IDF (Term Frequency-Inverse Document Frequency), Recurrent Neural Network (RNN) and a Dual Encoder (DE) based on Long …

Polarized Bow Shock Nebulae Reveal Features Of The Winds And Environments Of Massive Stars, Manisha Shrestha

Electronic Theses and Dissertations

Massive stars strongly affect their surroundings through their energetic stellar winds during their lifetime and through their energetic deaths as supernovae. When a stellar wind interacts with the local interstellar medium (ISM), if the relative velocity between wind and ISM is supersonic, then a stellar wind bow shock is formed. Bow shocks and related density enhancements produced by the winds of massive stars moving through the interstellar medium provide important information regarding the motions of the stars, the properties of their stellar winds, and the characteristics of the local medium. Since bow shock nebulae are aspherical structures, light scattering within …

Professor Who? A Phenomenological Exploration Of Working Professionals Who Feel Called To Teach As Adjunct Faculty, Molly A. Smith

Electronic Theses and Dissertations

This phenomenological study explores the meaning that those who feel called to teach make out of their adjunct teaching experience in higher education. In addition to understanding more about how these individuals describe their call to teach, the study explores how adjunct faculty characterize the relationship between personal identity, calling, and professional identity as a teacher. This study also explores how adjunct faculty articulate the relationship between their identity, teaching intentions, and professional practice. Five essential themes emerged as characterizing the phenomenon of feeling called to teach as an adjunct member in higher education, including (1) Enjoyment, (2) Alignment, (3) …

Nanoengineering Of Next Generation Silicone Rubber Materials For Extreme Applications, Monika Bleszynski

Electronic Theses and Dissertations

Silicone rubber materials are frequently used in extreme environments, including aviation, space, high voltage and other applications. In service, however, complex and difficult to predict damage mechanisms in the rubbers can occur which can lead to severe failures of essential infrastructural components. For example, Non-Ceramic Insulators (NCIs), which support some of the most critical high voltage lines in the world, regularly exhibit severe polymer aging due to environmental pollution, ultra-violet (UV) radiation, and dry band and corona arcing. Designing silicone rubbers to resist aging in these demanding environments is difficult and requires an interdisciplinary approach, including correctly assessing the actual …

Serial Murder Mysteries: Revisiting Definitional Issues, Data Challenges, Archaic Theories, And Myths Using Empirical Evidence, Jolene Vincent

Electronic Theses and Dissertations

While serial killings have been the focus of much scholarly research, the definition of what it means to be a serial killer has been debated by law enforcement agencies and academics for decades. This overall lack of understanding about serial killers and the murders they commit has contributed to the numerous limitations concerning the general knowledge about this unique form of homicide. Furthermore, serial killers have typically been examined using psychological models, psychiatric approaches, or the external drives/motives of the offenders, while the development of a sociological perspective has received less attention. This current research uses arguably the most complete …

Agreeing To Submit: Authority Constructions In Modern Sunni Islam, Trevor E. Wolff

Electronic Theses and Dissertations

In the modern age, Sunni communities are often claimed to be in a moment of crisis. However, despite outward arguments about this crisis, Sunni communities are more accurately described as within a state of transformation. By analyzing constructions of authority from Sayyid Qutb, the clerical establishment of Saudi Arabia, and the greater American Muslim communities, Sunni theology is best seen as seeking out methods to transform and re-center authority within Sunni communities.

Understanding Public Library Services And Use: A Structural Equation Modeling Framework, Ian Burke

Electronic Theses and Dissertations

This dissertation describes the process of fitting publicly available data from the 2015 Public Libraries Survey and 2015 American Community Survey to a structural equation model based on a theory of action for public libraries relating operating revenue to latent factors measuring service availability and library use within the context of matched community demographic data. The process of using theory-based data analysis to investigate publicly-available data is examined. Key findings include acceptable estimates of goodness-of-fit for hypothesized factors representing public library service availability and public library use, an inconsistent mediation effect of service availability on the relationship between public library …

Attachment Theory As A Framework For Supervision Of Supervisors-In-Training, Alyssa Fredricks

Electronic Theses and Dissertations

This focus of the study is on the training of new clinical supervisors in health service psychology, specifically the relational processes involved in learning and acquiring competence in clinical supervision. An effective learning environment is critical to supervisor training and development (Borders et al., 2014;Watkins, Budge, & Callahan, 2015) and attachment theory provides a framework for understanding the complex relationship domains and group dynamics inherent to group supervision. Given the recognition that the supervisory alliance is central to the process of competent supervision (APA, 2015), the purpose of this study is to explore the relationship between adult attachment style, the …

Predicting And Shifting Attitudes Toward Immigrants And Immigration: Testing A Model And Communication Strategy, Tejaswinhi Srinivas

Electronic Theses and Dissertations

Research in intergroup relations has found evidence for economic and moral explanations for negative attitudes toward immigrants and immigration (NATII), and has evaluated various communication strategies for shifting these attitudes. However, no research to date has provided a cultural explanation for NATII, or tested and compared the impact of communication strategies for reducing NATII, in the American context. This study extended prior research in three ways. First, we tested a model that linked various psychosocial factors together (i.e., right-wing authoritarianism, intergroup contact, cultural essentialism, and symbolic threat) to provide a cultural explanation for NATII. Second, we tested the effect of …

Predicting Help-Seeking Attitudes And Intentions In A Diné Sample, Chesleigh N. Keene

Electronic Theses and Dissertations

The purpose of the study was to investigate the relationship between cultural factors, psychological distress, barriers, and attitudes toward seeking psychological help among Diné tribal members. This study is in response to calls to consider psychological and cultural factors in the underutilization of mental health services by ethnic minorities. The present study examines psychological and cultural antecedents to seeking professional psychological help among Diné tribal members (N=119). It examined the mediating role of attitudes toward help seeking in the relationship between psychological distress, barriers to care, three acculturation variables, and intentions to seek counseling. Mediation was assessed with …

College Athletes And Romantic Relationship Conflict: The Moderating Effects Of Sport-Relationship Conflict And Enrichment, Keaton Clauss Muzika

Electronic Theses and Dissertations

Relationships that college athletes develop outside of their sports have the potential to positively and negatively impact sport, relationship, and mental health outcomes. Existing research focuses on the importance of the coach-athlete, parentathlete, and athlete-athlete dyads and suggests that these relationships affect athletes’ satisfaction and commitment to sport. However, few studies examine the influence of romantic relationships on these outcomes. This study, which is founded on work-family conflict and enrichment theories, used an experimental design to examine the moderating effects of sport-relationship conflict and enrichment on the relationship between romantic relationship conflict and athlete burnout, sport commitment, depression, and perceived …

Thriving With Down Syndrome: A Qualitative Multiple Case Study, Talia G. Thompson

Electronic Theses and Dissertations

Down syndrome (DS) is a chromosomal abnormality associated with intellectual disability (ID) and multiple medical complications. However, despite significant deficits related to the disability, there are people with DS who are thriving in our community. This dissertation examines those who thrive with DS and the individual and environmental factors that influence their thriving within two manuscripts. Manuscript One presents a synthesis of seminal and current positive psychology and disability studies literature. Review indicates that thriving with ID occurs when individuals report (a) a healthy transactional relationship between the individual and the ecological system; (b) high subjective well-being; and, (c) an …

Thermodynamic Modeling And Transient Simulation Of A Low-Pressure Heat Recovery Steam Generator Using Siemens T3000, Andres Caesar

Electronic Theses and Dissertations

With world energy consumption rising, and nonrenewable energy resources quickly depleting, it is essential to design more efficient power plants and thereby economically utilize fossil fuels. To that end, this work focuses on the thermodynamic modeling of steam power systems to enhance our understanding of their dynamic and transient behavior. This thesis discusses the physical phenomena behind a heat recovery steam generator (HRSG) and develops a mathematical description of its system dynamics. The model is developed from fundamentals of fluid dynamics, phase change, heat transfer, conservation laws and unsteady flow energy equations. The resulting model captures coupled physical phenomena with …

Electrochemical Microsensors For In Situ Monitoring Of Chemical Compounds In Engineered And Natural Aquatic Systems, Jared Church

Electronic Theses and Dissertations

The adaption of needle-type electrochemical microsensor (or microelectrode) techniques to environmental science and engineering systems has transformed how we understand mass transport in biotic and abiotic processes. Their small tip diameter (5-20μm) makes them a unique experimental tool for direct measurements of analytes with high spatial and temporal resolutions, providing a quantitative analysis of flux, diffusion, and reaction rate at a microscale that cannot be obtained using conventional analytical tools. However, their applications have been primarily limited to understanding mass transport dynamics and kinetics in biofilms. With the advancement of sensor fabrication and utilization techniques, their potential applications can surpass …

D-Fens: Dns Filtering & Extraction Network System For Malicious Domain Names, Jeffrey Spaulding

Electronic Theses and Dissertations

While the DNS (Domain Name System) has become a cornerstone for the operation of the Internet, it has also fostered creative cases of maliciousness, including phishing, typosquatting, and botnet communication among others. To address this problem, this dissertation focuses on identifying and mitigating such malicious domain names through prior knowledge and machine learning. In the first part of this dissertation, we explore a method of registering domain names with deliberate typographical mistakes (i.e., typosquatting) to masquerade as popular and well-established domain names. To understand the effectiveness of typosquatting, we conducted a user study which helped shed light on which techniques …

Macromolecule Loading On Plga Particles Through Surface Adsorption, Yiwei Wang

Electronic Theses and Dissertations

The advent of biotherapeutics have impacted the ways in which diseases are treated. In many instances development of recombinant proteins and oligonucleotides into therapeutics are slowed by poor stability of the candidate drugs. Progress has been made in using polymeric particles as carriers of macromolecule drugs. Historically the method is to encapsulate biological drugs into spherical polymeric matrices. Owing to its biocompatible and biodegradable nature, poly (d,l-lactic-co-glycolic acid) (PLGA) has been used extensively in formulating biological drugs into nano- and micro-sized particles. The development of PLGA biologic formulations, however, has been hampered by matrix acidification; the hydrolysis of the polymer …

Increasing Access To High-Impact Practices: A Case Study On Internships At The University Of Mississippi, Jennifer Saxon, Kristina Phillips

Electronic Theses and Dissertations

This dissertation-in-practice case study aimed to assess internships opportunities at the University of Mississippi (UM) to determine potential barriers for access among African American students and students with low socioeconomic backgrounds. Internships are a high impact practice, as identified by the American Association for Colleges and Universities (AAC&U) that provide students with tangible, real-world experience to prepare for careers after graduation. Experiential learning theories (Kolb, 1984; Dewey, 1938) and high-impact practices (Kuh, 2008) establish the importance of student engagement outside of traditional classroom settings. The patterns and frequency of internship participation are not clear for University of Mississippi students. Research …

Egfr Signaling From The Early Endosome., Julie A. Gosney

Electronic Theses and Dissertations

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is an integral component of proliferative signaling. When activated by a ligand at the plasma membrane, EGFR dimerizes with another ErbB family receptor, leading to kinase domain activation and transphosphorylation of C-terminus tyrosine residues. These phosphotyrosines act as crucial regulators of EGFR signaling as effector proteins dock to the receptor at these sites. The receptor undergoes clathrin-mediated endocytosis into early endosomes, where it can then be trafficked to a lysosome for degradation. However, the kinase domain of EGFR retains its activity during trafficking, suggesting that EGFR can continue …

Fostering Positive Emotion Through Self-Compassion In Individuals With Chronic Pain., Melissa E. Ellsworth

Electronic Theses and Dissertations

Previous research in chronic pain has established that reducing or removing negative aspects of functioning, such as negative emotion, maladaptive thoughts and behaviors are associated with better outcomes in this population. More limited is the research on the role of positive aspects of functioning in those with chronic pain, specifically exploring the benefits of positive emotion and how this can be bolstered in individuals with chronic pain. Limited research to date has explored strategies to promote positive aspects of functioning, including savoring, gratitude, and mindfulness, but even more limited is research exploring the role of self-compassion as a resource for …

A Structural Equation Analysis Of The Relationships Between Ptsd, Depressive Symptoms And Suicidal Ideation : Is General Strain Theory A Viable Framework For Explaining Suicide Risk Among Correctional Staff?, Wm. Clay Johnson

Electronic Theses and Dissertations

There is a large body of evidence, which suggests PTSD is strongly related to increased suicide risk, however, some studies suggest the true nature of their relationship is better explained through the development of depression due to the effects of PTSD. While a majority of the studies examining this relationship focus only on general populations, a growing body research suggests that high-risk occupations such as police, firefighters and correctional staff are developing PTSD at rates as high as 8 to 10 times that of the rate of these general samples. This study, then, aims to fill a small gap in …

Cannabidiol Alters The Immune Response To Porphyromonas Gingivalis In Mice., Shilpa Singh

Electronic Theses and Dissertations

Background: Porphyromonas gingivalis is an important etiologic agent of chronic periodontitis, an infectious disease defined by destruction of supporting tissues of the teeth. Marijuana is a risk factor for chronic periodontitis, although underlying mechanisms are poorly understood. As phytocannabinoids have been ascribed antiinflammatory properties, we hypothesized that cannabidiol exposure would lead to altered immune response to P. gingivalis infection facilitating bacterial persistence and, subsequently, increased alveolar bone loss in cannabidiol (CBD)-exposed mice. Methods: P. gingivalis-infected cannabinoid receptor 2 (CB2) knockout and wild type C57/Bl6 mice were exposed, or not exposed, to cannabidiol. Oral swabs from mice were used to monitor …

Uncertain Certainties: An Analysis Of The American Response To The 2014-2016 West African Ebola Epidemic., Kelly Carty

Electronic Theses and Dissertations

This project examines the construction of scientific facts surrounding the 2014-2016 West African Ebola outbreak as well as the subsequent uptake and transformation of those facts by the United States government. While the Ebolavirus ravaged the communities of Sierra Leone, Liberia, and Guinea, the incidence of the virus in other countries was very low. Nonetheless, the United States spent $576 million on domestic preparedness and response. This study addresses this mismatch in the context of the reinvigorated interest among rhetoricians into writing and science. Applying and expanding the methodology of Jeanne Fahnestock, this study analyzes Ebola-related statements in scientific articles, …

Post-Diagnosis Quality Of Life And Mortality In Non-Hispanic White And Hispanic Women Diagnosed With Invasive Breast Cancer., Delvon T. Mattingly

Electronic Theses and Dissertations

The prevalence of breast cancer is increasing, and the health-related quality of life (HRQOL) of breast cancer survivors may help to further understand survivorship. This study evaluated HRQOL as a potential prognostic factor for mortality among Non-Hispanic White (NHW) and Hispanic women diagnosed with invasive breast cancer. Data were used from the Health, Eating, Activity, and Lifestyle (HEAL) Study. Data for 351 participants were analyzed for associations between HRQOL scores (subscale, component) and mortality. Cox proportional hazards regression was conducted to assess the relationship between HRQOL and mortality outcomes (all-cause, breast cancer-specific, non-cancer). Median follow-up time from HRQOL assessment (approximately …

Wnt/Β-Catenin Mediated Cancer Stem Cell Activation In Hepatocellular Carcinoma., Harshulkumar M. Pandit

Electronic Theses and Dissertations

Hepatocellular carcinoma (HCC) is one of the deadliest cancers, with variable presentation, high chemotherapy resistance and early tumor recurrence. In this dissertation, we have systematically enriched, identified and characterized HCC cancer stem cells (CSCs) from 3 different HCC cell lines (Hepa1-6, HepG2, and Hep3B) using in vitro serum-free culture method. Enriched spheroids acquired CSC properties, primarily self-renewal capability, spheroid formation ability, and drug resistance. Heterogeneous CSCs enriched from Hepa1-6 cells demonstrated higher tumor initiation and proliferation capability in vivo, compared to control HCC cells in orthotopic immunocompetent mouse model. EpCAM+ CSCs were significantly enriched within heterogeneous Hepa1-6 CSC spheroids. Consequently, …

Social Determinants Of Health And A Grounded Mixed-Methods Approach To Explain Declining Life Expectancy In Eastern Kentucky : 1980 – 2014., William Renda

Electronic Theses and Dissertations

Trends in life expectancy for the United States from 1980-2014 suggest general improvement overall. However, eastern Kentucky stands out with a cluster of counties experiencing declining life expectancy. Given that life expectancy is an excepted indicator of overall population health, this anomaly in eastern Kentucky warrants investigation. This thesis uses a grounded mixed methods approach to explore this trend across the greater Appalachian region. Content and discourse analysis of interviews with public health and medical professionals in the study area revealed key themes perceived as being related to declining life expectancy, which informed variable selection for regression analysis. Regression models …

The N-Terminal Methyltransferase Homologs Nrmt1 And Nrmt2 Exhibit Novel Regulation Of Activity Through Heterotrimer Formation., Jon David Faughn

Electronic Theses and Dissertations

Protein, DNA, and RNA methyltransferases have an ever-expanding list of novel substrates and catalytic activities. Even within families and between homologs, it is becoming clear the intricacies of methyltransferase specificity and regulation are far more diverse than originally thought. In addition to specific substrates and distinct methylation levels, methyltransferase activity can be altered through formation of complexes with close homologs. This work involves the N-terminal methyltransferase homologs NRMT1 and NRMT2. NRMT1 is a ubiquitously expressed distributive trimethylase. NRMT2 is a monomethylase expressed at low levels and in a tissue-specific manner. They are both nuclear methyltransferases with overlapping target consensus sequences …

A Cancer-Targeted Gold Nanoparticle-Based Mri Contrast Agent., Nagwa El-Baz

Electronic Theses and Dissertations

In oncology, imaging plays a major role in terms of early detection and treatment of most types of cancer. Magnetic resonance imaging (MRI) is mostly used for cancer diagnosis due to its excellent contrast resolution. However, MRI for cancer diagnosis is somewhat limited by its sensitivity. In this thesis, we assessed the ability of theranostic platform consisting of gold nanoparticles functionalized with a cancer targeting aptamer; AS1411 and gadolinium chelate (Dotarem thiol derivative; Gd (III)-DO3A) as a MRI contrast agent to target malignant tumors by enhancing the MRI contrast of the detected tumor. The proposed technology is a novel injectable …

Macro-Level Predictors Of Assaults Against Police In Kentucky., Virginia Paulette Redman

Electronic Theses and Dissertations

Law enforcement is one of the most dangerous careers. Every day, while performing their jobs, police officers may find themselves in situations that place them at a high risk of being victimized or even feloniously killed by members of the public. Over the past five decades, several quantitative and qualitative research studies tried to identify the circumstances and the individual-level factors associated with an increased risk of police victimization. While most of the research studies focusing on police victimization were descriptive and/or were based on micro-level analyses, macro-level research on this topic is relatively scant. This dissertation intends to reduce …