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Articles 7021 - 7050 of 35619
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Crispr/Cas9 Whole Genome Screens Reveal Novel Regulators Of Endocytic Processes In Macrophages, Jared Wollman
Crispr/Cas9 Whole Genome Screens Reveal Novel Regulators Of Endocytic Processes In Macrophages, Jared Wollman
Electronic Theses and Dissertations
Macrophages maintain tissue homeostasis by identifying and eliminating threats within their tissue microenvironment. Pattern recognition receptors allow macrophages to recognize and internalize specific ligands while macropinocytosis allows the internalization of all extracellular solutes from their environment. Without pattern recognition receptors, pathogens may grow unchecked if they cannot be detected, and without macropinocytosis, macrophages struggle to detect and move around their environment. This thesis presents the results of CRISPR/Cas9 whole-genome screens used to identify the regulators of both endocytosis (Chapter 2) and macropinocytosis (Chapter 3). In Chapter 2, we report genes regulating dextran uptake in primary murine macrophages and reveal Mrc1-mediated …
Evolutionary History Of Subterranean Termites In The Geographic And Ecological Context Of The Appalachian Mountains In The United States, Chaz Hyseni
Electronic Theses and Dissertations
Termites in the genus Reticulitermes (Blattodea: Rhinotermitidae) are distributed across the eastern United States, including the southern Appalachian Mountains, a region incredibly rich in biodiversity. The eastern subterranean termite, Reticulitermes flavipes, has been uninentionally introduced to South America and Europe, and is predicted to further expand its geographic range. My goal was to determine how eco-evolutionary processes, operating at both long and short timescales, may have contributed to R. flavipes becoming an invasive species. I examined geographic and environmental influences at historical and contemporary timescales. To do this, I first determined the extent of niche divergence among three geographically overlapping …
Winter Patch Grazing, Patch Burn Grazing, And Bird Communities In Western South Dakota, Jennifer Lutze
Winter Patch Grazing, Patch Burn Grazing, And Bird Communities In Western South Dakota, Jennifer Lutze
Electronic Theses and Dissertations
Ground nesting bird species are on a considerable decline and research efforts are being made to increase these populations throughout the Great Plains. Ground nesting bird communities found in the Northern Great Plains are driven greatly by varying amounts of cover and area size. Past research implemented patch-burn grazing to increase structural heterogeneity and to increase grassland bird habitat in the tallgrass prairie. While bird populations were very responsive to this management in the Northern Great Plains fire management is viewed negatively, especially for Midwest cattle ranchers. We implemented research to determine if winter-patch grazing on mixed grass prairie could …
Socioeconomic Determinants Of Expenditures On Fortified And Unfortified Fruit Juice, Cole Sellnow
Socioeconomic Determinants Of Expenditures On Fortified And Unfortified Fruit Juice, Cole Sellnow
Electronic Theses and Dissertations
As of 2019, fruit beverages comprise an $11 billion industry in the US (Juice Production in the US 2019). There has been a recent push for fortification of fruit juices due to rising consumer health concerns such as obesity and high sugar consumption. Additionally, the 2015-2020 Dietary Guidelines for Americans recommend limiting fruit beverage consumption (Dietary Guidelines Advisory Committee 2020). While there is a rich set of literature analyzing determinants of fruit beverage demand, there is a lack of research analyzing which factors drive consumer expenditures on fortified and unfortified fruit juices (Yen et al. 2004; Storey et al. 2006; …
Characterization Of Bacterial Endophytes Isolated From Brassica Carinata And Their Potential Use To Decrease Nutrient Requirements In Crops, Alex Soupir
Electronic Theses and Dissertations
Bacterial endophytes have the capability to enhance plant growth by producing plant growth hormones, solubilizing phosphates, suppressing pathogenic fungi, and reducing plant stress hormones. These capabilities make them desirable limiting the amount of nutrients and pesticides that are applied to crops. Through these assays and isolations, it is possible to identify novel bacterial species. In-vitro testing had shown 9 of the 20 isolates possess the ability to produce indole-3-acetic acid (IAA) with Pantoea agglomerans BC09 producing a concentration of 30.2 ng/μl over 4 days. BC09, Bacillus subilis BC10, and Pantoea sp. BC12 were able to solubilize calcium phosphate, 7 endophytes …
Partitioning Variation In Measurements Of Beef Carcass Traits Made Using Ultrasound, Bradie M. Schmidt
Partitioning Variation In Measurements Of Beef Carcass Traits Made Using Ultrasound, Bradie M. Schmidt
Electronic Theses and Dissertations
Ultrasound technology provides cattle breeders a relatively quick, non-invasive, and economical way to gather carcass data on live animals. Ultrasound provides the means to accurately predict body composition and develop estimated breeding values; however, national cattle genetic evaluations assume homogenous additive genetic and residual variances. These assumptions may be violated when estimating genetic merit for carcass traits by ultrasound because of differences in variance due to scanning technician and image interpretation laboratory. The objective of this study was to partition the phenotypic variance of measurements of carcass traits that were made using ultrasound into components attributable to additive genetic effects, …
Molecular Facet Of Host-Pathogen Interactions In Fusarium Head Blight In Wheat ( Triticum Aestivum L.), Bimal Paudel
Molecular Facet Of Host-Pathogen Interactions In Fusarium Head Blight In Wheat ( Triticum Aestivum L.), Bimal Paudel
Electronic Theses and Dissertations
Fusarium head blight (FHB) is a severe disease of wheat (Triticum aestivum L.). It not only reduces the quantity of the harvested grains but also decreases the grain quality due to mycotoxins contamination, especially Deoxynivalenol (DON). Qfhb1 (or simply called Fhb1) is the most important quantitative trait locus (QTL) for FHB resistance. Our lab has previously identified wheat gene WFhb1-1 (aka. Wfhb1_c1) as a candidate for FHB resistance gene. Here we report that WFhb1-1 has been cloned. The gene (GenBank # KU304333.1) consists of a single exon, encoding a putative membrane protein of 127 amino acids. WFhb1-1 protein produced in …
The Relationship Between Food Rules And Childhood Obesity In Rural And Non-Rural Families, Anna Venjohn
The Relationship Between Food Rules And Childhood Obesity In Rural And Non-Rural Families, Anna Venjohn
Electronic Theses and Dissertations
Background: Childhood obesity is continuing to rise, leading to long-term health consequences. Research shows that rural populations have higher rates of childhood obesity. There is a lack of research on how the home environment may affect this health disparity. Parents often enforce food rules to control their child’s eating habits, but the difference between the rural and non-rural populations in enforcing these rules is unknown.
Purpose: The purpose of the present study was to determine if there is a significant difference in food rules between rural and non-rural school-aged children, and if these differences correlate to BMI categories.
Methods: Secondary …
Development Of Analytical Methods For Toxic Inhaled Hazards (Tih) And Their Metabolites, Obed Adu Gyamfi
Development Of Analytical Methods For Toxic Inhaled Hazards (Tih) And Their Metabolites, Obed Adu Gyamfi
Electronic Theses and Dissertations
Toxic inhalation hazards (TIHs), such as methyl isocyanate (MIC) and hydrogen cyanide (HCN), are noxious gases and vapors that are harmful, and often deadly, to humans. However, because of their low cost and high reactivity, they are extensively used for industrial productions, creating risk of exposure for both industrial workers (e.g., occupational exposure) and civilians (e.g., accidental release during transport). The illicit use of TIHs, including as terrorist agents, is also concerning. Considering the rapid toxicity of TIHs and the danger they pose to both human and animal lives, there is a critical need to develop of analytical methods for …
Optimization Of Conditions For Heat Pretreatment And Enzymatic Predigestion Of Ddgs For Pigs, Kevin Jerez-Bogota
Optimization Of Conditions For Heat Pretreatment And Enzymatic Predigestion Of Ddgs For Pigs, Kevin Jerez-Bogota
Electronic Theses and Dissertations
The high fiber content of corn dried distillers’ grains with solubles (DDGS) can limit its utilization in swine diets. Pretreatment with heat and enzymatic predigestion of whole stillage (WS; slurry material that is dried into DDGS) can alleviate negative effects of dietary fiber and can improve digestive and fermentation characteristics of the feedstuff. However, optimal time and temperature of the heat pretreatment of WS, and best enzymes for predigestion of WS have not been identified. Experiments were conducted to identify optimal conditions for heat pretreatment and multienzyme predigestion of WS for pigs. First experiment was conducted to identify optimal temperature …
Student-Faculty Interactions As Predictors Of Retention And Satisfaction Among Generation Z College Students, Stephani Jarecke
Student-Faculty Interactions As Predictors Of Retention And Satisfaction Among Generation Z College Students, Stephani Jarecke
Electronic Theses and Dissertations
Student retention has historically been an important discussion in higher education. While the importance of student retention remains, a new generation of students have filled colleges and universities. This study examines how interactions with faculty influence Generation Z college students’ overall satisfaction and student retention. The quantitative study used the NSSE survey instrument at a public land-grant institution in the Midwest. The results of a Mann-Whitney U analysis indicated a significant difference in student satisfaction reported between students who returned to the same institution the following year and students who did not return. A multiple linear regression analysis indicated that …
Genetic Study Of Alkane Production And Oxic Nitrogen Fixation In Anabaena Sp. Pcc 7120, Jaimie L. Gibbons
Genetic Study Of Alkane Production And Oxic Nitrogen Fixation In Anabaena Sp. Pcc 7120, Jaimie L. Gibbons
Electronic Theses and Dissertations
Anabaena sp. PCC 7120 is a filamentous, nitrogen-fixing cyanobacterium that uses spatial separation to perform photosynthesis and nitrogen fixation simultaneously. Under fixed nitrogen limiting conditions, Anabaena 7120 forms specialized cells, called heterocysts, to fix nitrogen. In this research, I sought to add to the knowledge surrounding the process of heterocystous nitrogen fixation in Anabaena 7120. Cyanobacteria universally produce alkanes, which have been suggested to play a role in helping the organism adapt to abiotic stress, such as diazotrophic conditions. In my first study, I sought to identify the genes required for production of the hydrocarbon heptadecane (C17H36). Through using a …
Two-Dimensional Nanomaterials And Their Composites For Electrochemical Detection Of Toxic Mercury Ions In Water, Md Tawabur Rahman
Two-Dimensional Nanomaterials And Their Composites For Electrochemical Detection Of Toxic Mercury Ions In Water, Md Tawabur Rahman
Electronic Theses and Dissertations
The presence of trace amounts of mercury ion (Hg2+) in drinking water has a detrimental effect on human health. The development of an electrochemical sensor for Hg2+ detection is still challenging to obtain ultra-trace sensitivity, excellent selectivity, wide Linear Detection Ranges (LDRs), and ultra-low detection limit. This work presents an electrochemical sensor based on two-dimensional nanomaterials and their composites for the enhanced sensing of Hg2+ in water. Graphene oxide (GO)-silver nanowires (AgNWs) composite and metallic 1T phase tungsten disulfide (WS2) microflowers were utilized for the fabrication of electrochemical sensors using drop-casting. Under the optimized experimental conditions, …
Phytoremediation Of Saline-Sodic Soils In East Central South Dakota Utilizing Perennial Grass Mixtures, Douglas J. Fiedler
Phytoremediation Of Saline-Sodic Soils In East Central South Dakota Utilizing Perennial Grass Mixtures, Douglas J. Fiedler
Electronic Theses and Dissertations
Several decades of above average precipitation in South Dakota has increased the area of saline and sodic soils, which reduce crop yields and inhibit sensitive plant growth. Saline and sodic soils are difficult to remediate using traditional agricultural crops. Establishing salt tolerant perennial species may restore productivity to salt affected areas. Two perennial grass mixtures (mix 1: slender wheatgrass, beardless wildrye; mix 2: slender wheatgrass, western wheatgrass, green wheatgrass, creeping meadow foxtail) were dormant frost seeded along a topographic gradient in Clark Co., SD. Soils were Forman-Cresbard loam and a Cresbard-Cavour loam with surface electrical conductivity (EC1:1) that …
Determination Of The Gyro-Electric Reflection And Transmission Coefficients In The Fused Quartz Itop Cherenkov Particle Id Detectors At The Belle Ii Experiment, Michael Jeandron
Determination Of The Gyro-Electric Reflection And Transmission Coefficients In The Fused Quartz Itop Cherenkov Particle Id Detectors At The Belle Ii Experiment, Michael Jeandron
Electronic Theses and Dissertations
The thesis presents new results for the reflection and transmission coefficients for Cherenkov photons in a strong magnetic field at the interface between the fused quartz of and the surrounding nitrogen gas within the iTOP particle detector, a sub-system of the Belle II experiment. The iTOP is a component of the particle identification system at Belle II which distinguishes between kaons and pions in final states after collision. These coefficients are important in understanding how photons propagate through the iTOP taking into consideration polarization at the reflection and transmission interfaces in the Belle II magnetic field because the polarization affects …
A War Of Ideas: L.Q.C. Lamar And American Political Thought, Ashley Steenson
A War Of Ideas: L.Q.C. Lamar And American Political Thought, Ashley Steenson
Electronic Theses and Dissertations
This thesis connects late nineteenth-century southern Democrat and former Confederate L.Q.C. Lamar to the status politics of the Northeastern “small imperialist elite.” Moreover, this work traces Senator, Secretary of the Interior, and Associate Justice Lamar’s legacies in American political thought, such as a regional memorialization and the example of his national influence through the policies of President Theodore Roosevelt specifically. Though he inspired generations of politicians with varying views, Lamar himself maintained a strict constructionist political philosophy and worked for home rule throughout his career. Scholars argue for Lamar as a moderate symbol of national reconciliation due to his eulogy …
What's Next? The Intersection Of Politics And Marketing: A Look At Its Impact On Shareholder Wealth, Ashley Morgan
What's Next? The Intersection Of Politics And Marketing: A Look At Its Impact On Shareholder Wealth, Ashley Morgan
Electronic Theses and Dissertations
The first essay attempts to explain the heterogeneity in the stock market’s reaction to a firm’s lobbying for good efforts. It is hypothesized that higher (a) CEO equity-to-pay ratio, (b) marketing influence in the TMT, (c) marketing capabilities, (d) corporate social performance, and (e) institutional ownership, will be associated with less negative abnormal stock returns. Results indicate that firms with a greater amount of marketing influence in the top management team experience greater negative abnormal returns. While firms with a higher CEO equity-to-pay ratio and a greater level of institutional ownership experience less negative abnormal returns. The second essay explores …
Learning Lineage And The Problem Of Authenticity In Ozark Folk Music, Kevin Lyle Tharp
Learning Lineage And The Problem Of Authenticity In Ozark Folk Music, Kevin Lyle Tharp
Electronic Theses and Dissertations
ABSTRACT Thorough examination of the existing research and the content of ballad and folk song collections reveals a lack of information regarding the methods by which folk musicians learn the music they perform. The centuries-old practice of folk song and ballad performance is well-documented. Many Child ballads and other folk songs have been passed down through the generations. Oral tradition is the principal method of transmission in Ozark folk music. The variants this method produces are considered evidence of authenticity. Although alteration is a distinguishing characteristic of songs passed down in the oral tradition, many ballad variants have persisted in …
Formulation And Optimization Of Fingolimog Hydrochloride Nanoemulsion, Rama Avinash Kashikar
Formulation And Optimization Of Fingolimog Hydrochloride Nanoemulsion, Rama Avinash Kashikar
Electronic Theses and Dissertations
The goal of the present study was to develop a nanoemulsion (NE) system for efficient and prolonged delivery of Fingolimod Hydrochloride (FTY720; FT), to the posterior segment of the eye through the topical route. FT is a sphingosine-1-phosphate receptor agonist, an immunosuppressive agent. FT loaded NE (FT-NE) formulations were prepared with the homogenization method, using Soybean oil as lipid, Tween® 80 and Poloxamer 188 as surfactants. FT-NE were optimized based on particle size, zeta potential (ZP), Polydispersity Index (PDI) and assay. optimized FT-NE formulation were further evaluated for in vitro release and transcorneal in comparison with FT solution (FT-S) formulation, …
How Newspapers' Social Media Editors In Bangladesh Use Official Social Media Accounts, Ahmed Shatil Alam
How Newspapers' Social Media Editors In Bangladesh Use Official Social Media Accounts, Ahmed Shatil Alam
Electronic Theses and Dissertations
For the last several years, the newspaper industry in Bangladesh has been using social media for disseminating news and connecting with readers. But the question remains how the social media journalists are using these social media accounts and what roles they perform every day in the newsrooms. This exploratory study sheds light on both issues through the lens of the Gatekeeping Theory. Following interviews with 13 social media journalists who worked for 11 national newspapers in Bangladesh, the study found that the overall traditional gatekeeping roles of these journalists had undergone substantial changes as they were heavily concerned about audience …
Beautiful And Terrible In The Face: Reconfiguring The Southern Beauty Myth Through The Short Fiction And Autobiographical Writings Of Eudora Welty, Katherine Elizabeth Howell
Beautiful And Terrible In The Face: Reconfiguring The Southern Beauty Myth Through The Short Fiction And Autobiographical Writings Of Eudora Welty, Katherine Elizabeth Howell
Electronic Theses and Dissertations
From her personal appearance as the “ugly duckling” of southern literature, to her narrative preoccupations as a writer of grotesques, Eudora Welty has been critically separated from the realm of southern beauty and femininity. Drawing textual evidence from Welty’s strategic invocation of beauty acts and products in her short fiction and autobiographical writings, this thesis insists upon Welty’s lifelong stake in beauty culture, as it is practiced by southern women across the socioeconomic spectrum. Across her body of short fiction—a substantial portion of which was first published in women’s fashion magazines—Welty details the ways in which beauty, as expressed through …
It's A Cis-Gendered Man's World: How Drag Kings Define Good Drag In Their Fight To Be Seen As The Best Performers, Madison Shappley
It's A Cis-Gendered Man's World: How Drag Kings Define Good Drag In Their Fight To Be Seen As The Best Performers, Madison Shappley
Electronic Theses and Dissertations
This research is based on field observations in Ridgeville, a Southern city, at an LGBTQ bar, that I call Rainbow Bar and on in-depth interviews with Rainbow Bar drag performers. Through my study at Rainbow, I set out to answer: 1) What do drag kings consider to be “good drag” for themselves and for other kings?; and 2) Who is considered to have the best drag? And who determines what the best drag is? I found that Ridgeville drag kings felt as though they had to work harder than Ridgeville queens in their drag. To have good drag, Ridgeville kings …
Here, Now, Gabrielle Maria Dinger
Here, Now, Gabrielle Maria Dinger
Electronic Theses and Dissertations
My work explores the transformation of one’s self through the observation, collection, and exploration of nature. I am drawn to the moments that prompt change within each of our lives, and how these moments alter our interpretation of our surroundings. Although I am interested in creating a universal conversation about our interactions in nature, the work I create focuses on my own experiences. Through the exploration, collection, and alteration of objects, I create art for the viewer to investigate and contemplate their own interactions with nature. Through the act of exploration, my curiosity for the natural world and keenness for …
Integrated Psychological Services In Pediatric Primary Care: A Program Evaluation, Kristen Laprade Johnson
Integrated Psychological Services In Pediatric Primary Care: A Program Evaluation, Kristen Laprade Johnson
Electronic Theses and Dissertations
Many children and youth experience emotional and/or behavioral health difficulties and lack appropriate access to care. Access to care limitations are particularly relevant to rural populations such as Mississippi. Integrated care models could serve as an innovative solution to increasing access to care for children and youth. In particular, the Three World View model of integrated care asserts that attention should be given to the clinical world (i.e., provision of evidence based services), operational world (i.e., charting, scheduling, referrals, etc.), and the financial world (i.e., funding and reimbursement). The current study utilized program evaluation tools to develop and evaluate a …
Exploring The Relationship Between Receipt Of A Mississippi Need-Based State Grant And Grade Point Average Among Graduating Seniors At The University Of Mississippi, Clate A. Holleman
Exploring The Relationship Between Receipt Of A Mississippi Need-Based State Grant And Grade Point Average Among Graduating Seniors At The University Of Mississippi, Clate A. Holleman
Electronic Theses and Dissertations
This dissertation in practice (DiP) studies the relationship between the receipt of the Mississippi Higher Education Legislative Plan for Needy Students (MS-HELP) Grant and cumulative grade point average (GPA) at the beginning of their graduating term among graduating senior students at the University of Mississippi (UM). This study relies on the metric of Expected Family Contribution (EFC), which is a dollar amount generated by the Free Application for Federal Student Aid (FAFSA) designed to measure the amount of money a household can reasonably be expected to contribute to higher education. The MS-HELP Grant is a need-based grant provided by the …
Come Clean, Joshua Nguyen
Come Clean, Joshua Nguyen
Electronic Theses and Dissertations
"Come Clean" is a poetry collection.
Behavioral Chronopharmacology Of Cannabinoids In Young And Aged Mice, Erik Lewis Hodges
Behavioral Chronopharmacology Of Cannabinoids In Young And Aged Mice, Erik Lewis Hodges
Electronic Theses and Dissertations
The overarching goal of this research is to explore the biological mechanisms of aging and formulate novel therapeutic approaches to mitigate age-related impairments. The presence and pervasiveness of ~24 hour (circadian) rhythms in molecular and behavioral dynamics suggests that the mechanisms regulating these rhythms are integral to biological aging and possibly amenable to therapeutic interventions. Based on evidence presented in this dissertation, we conclude that the endocannabinoid system is a mediator of both central and peripheral circadian physiology. Additionally, the hormetic pharmacological properties of the synthetic cannabinoid CP55940 suggest that bidirectional modulation of circadian rhythms via cannabinoids is possible. Chapter …
Novel Ophthalmic Formulations For Improved Natamycin Delivery In Fungal Infections Of The Eye., Akash Vijay Patil
Novel Ophthalmic Formulations For Improved Natamycin Delivery In Fungal Infections Of The Eye., Akash Vijay Patil
Electronic Theses and Dissertations
Natamycin (NT) is a front-line drug in the management of ocular fungal infections (OFI). An ophthalmic marketed NT suspension (Natacyn®) is currently the only FDA approved medication prescribed in the pharmacotherapy of OFI. Current NT pharmacotherapy requires frequent topical administration (every hour or 2-hours over 6-8 times in a day) due to it being instilled as eye-drops. This leads to higher precorneal losses and subsequent poor permeation and bioavailability. Therefore, in this research study, alternative ocular formulations of NT were investigated with an intent to improve precorneal retention and corneal permeation in comparison to Natacyn®. Chapter 1 discusses various aspects …
Maurice E. Peloubet: A Life Of Impact On Accountancy And Society, Brandi Holley
Maurice E. Peloubet: A Life Of Impact On Accountancy And Society, Brandi Holley
Electronic Theses and Dissertations
Maurice E. Peloubet was one of accountancy’s major players during the profession’s highly evolutionary period in the United States from before World War I to the Vietnam War. Though Peloubet spent his entire career from 1911 to 1964 in public accounting, he also promoted the profession on the academic, governmental, and international fronts. This dissertation explores his contributions to the profession of accountancy and in turn society at large. Particular focus is placed on his role in the evolution of the American Institute of Certified Public Accountants (AICPA), his lobbying efforts before Congress concerning the Last-In, First-Out (LIFO) Inventory method …
Stress, Burnout, Compassion Satisfaction, And Compassion Fatigue Among Resident Assistants At The University Of Mississippi, Lionel Maten
Stress, Burnout, Compassion Satisfaction, And Compassion Fatigue Among Resident Assistants At The University Of Mississippi, Lionel Maten
Electronic Theses and Dissertations
The study explores the lived experience of Resident Assistants at the University of Mississippi regarding stress, burnout, compassion satisfaction, and compassion fatigue to help improve paraprofessional development. The study addresses a scarcity of research on the prevalence and severity of RA’s stress and burnout in their roles as caregivers. A qualitative design approach was designed for this study to investigate insightful perspectives and implications of the complexities of stress, burnout, compassion satisfaction, and compassion fatigue among RAs at the University of Mississippi. For this study, 15 RAs were selected to participate in semi-structured interviews to facilitate for further probing questions …