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Roles Of Endothelial Cell Heat Shock Protein A12b And Β-Glucan, A Reagent For Trained Immunity In The Regulation Of Inflammation In Sepsis, Fei Tu Aug 2020

Roles Of Endothelial Cell Heat Shock Protein A12b And Β-Glucan, A Reagent For Trained Immunity In The Regulation Of Inflammation In Sepsis, Fei Tu

Electronic Theses and Dissertations

Sepsis is dysregulated host immune response to infection causing life-threatening organ dysfunction. Endothelial cell dysfunction and uncontrolled inflammatory responses are two contributors for sepsis-induced mortality. The crosstalk between endothelial and immune cells plays a critical role in the pathophysiology of sepsis. Therefore, understanding the mechanism of interaction between endothelial and immune cells will provide novel information to develop therapeutic strategies for sepsis.

Pathogen associated moleculear patterns (PAMPs) and/or damage associated molecular patterns (DAMPs) produced during sepsis, activate endothelial cells to increase the expression of adhesion molecules, attracting immune cell infiltration into the tissues. Uncontrolled inflammatory responses during the early phase …


Thwarted Interpersonal Needs, Depression, And Sleep Disturbances In Primary Care: Does Gratitude Help You Sleep?, Heather R. Altier Aug 2020

Thwarted Interpersonal Needs, Depression, And Sleep Disturbances In Primary Care: Does Gratitude Help You Sleep?, Heather R. Altier

Electronic Theses and Dissertations

Sleep disturbances are prevalent in primary care patients and can be exacerbated by interpersonal dysfunction and depression. As well, thwarted interpersonal needs (TIN), including thwarted belongingness and perceived burdensomeness, contribute to depression. However, the presence of gratitude, a cognitive-emotional protective factor, may improve symptoms. We longitudinally examined the mediating role of depressive symptoms on the relation between TIN and sleep disturbances, and the moderating role of gratitude on the TIN-sleep disturbances and depression-sleep disturbances linkages. Our primary care patient sample (N = 223) completed self-report surveys at baseline (T1) and at a one-year follow-up (T2; n = 97). Patients …


Examining The Relationship Among Middle School Students’ Performance On The Tnready Assessment, District Checkpoints, And Teacher-Assigned Grades, Kristina Dempsey Aug 2020

Examining The Relationship Among Middle School Students’ Performance On The Tnready Assessment, District Checkpoints, And Teacher-Assigned Grades, Kristina Dempsey

Electronic Theses and Dissertations

The purpose of this nonexperimental, quantitative study was to determine if there is a significant correlation among teacher-assigned grades (TAG), district checkpoint scores (CP), and student scale-scores on TNReady tests. The focus was on 1,445 seventh and eighth grade students who were enrolled at a middle school in northeast Tennessee during the academic years of 2017-2018 and 2018-2019, specifically for the content areas of English Language Arts and mathematics. The second purpose of this study was to examine any moderating effects of the categorical variable, students with disabilities (SWD) status, on the correlations among the district and state assessments and …


Examining The Warm Handoff In Rural Integrated Care, Jamie Tedder Aug 2020

Examining The Warm Handoff In Rural Integrated Care, Jamie Tedder

Electronic Theses and Dissertations

An ever-growing body of evidence supports the efficacy of integrated care as a treatment approach; however, less is known about what specific components of integrated care are most effective. This is especially true of warm handoffs, which are an often discussed but understudied process in integrated care. A total of 246 patient charts were reviewed to determine if type of referral (warm handoff or traditional) increased the likelihood of follow-up with behavioral health services as well as factors that might impact this relationship. There were no significant differences between type of referral and likelihood of follow-up with behavioral health services. …


Assessing The Impact Of Restored Wetlands On Bat Foraging Activity Over Nearby Farmland, Philip Allagas Aug 2020

Assessing The Impact Of Restored Wetlands On Bat Foraging Activity Over Nearby Farmland, Philip Allagas

Electronic Theses and Dissertations

Up to 87% of the world’s wetlands have been destroyed, considerably reducing ecosystem services these wetlands once provided. More recently, many wetlands are being restored in an attempt to regain their ecosystem service. This study seeks to determine the effects of restored wetlands on local bat habitat use. Bat activity was found to be significantly higher around the wetlands when compared to distant grassy fields; however, no significant difference was found among the restored wetlands and a remote cattle farm containing multiple water features. Geospatial models of bat distribution and bat foraging were produced using machine learning that showed higher …


Axonal Regrowth Of Olfactory Sensory Neurons After Chemical Ablation And Removal Of Axonal Debris By Microglia, Rudy Chapman Aug 2020

Axonal Regrowth Of Olfactory Sensory Neurons After Chemical Ablation And Removal Of Axonal Debris By Microglia, Rudy Chapman

Electronic Theses and Dissertations

Olfactory sensory neurons (OSNs) are contained within the olfactory epithelium (OE) and are responsible for detecting odorant molecules in the air. The exposure of OSNs to the external environment is necessary for their function, but it also leaves them exposed to potentially harmful elements and thus results in a high turnover rate. Despite the high turnover, the olfactory sense is maintained throughout life through the division of a population of stem cells that produce new OSNs both during normal turnover and after an injury occurs in the OE. When new OSNs are born, they must extend axons from the OE …


Head Start Preschool Teachers’ Perceptions Of Reggio Emilia Principles Practiced Within Their Own Setting: A Case Study, Tara Terry Voit Aug 2020

Head Start Preschool Teachers’ Perceptions Of Reggio Emilia Principles Practiced Within Their Own Setting: A Case Study, Tara Terry Voit

Electronic Theses and Dissertations

The Reggio Emilia Approach (REA) and Head Start (HS) value high-quality early education, support for families, and community partnerships according to the literature. Exploring principles of REA in relation to the HS program model may reveal alignment that will inform high-quality developmentally appropriate practices that are meaningful and enhance learning outcomes. This multiple case study explores the REA in alignment within three Head Start programs in New Mexico, Massachusetts, and Tennessee. Participant groups include one education director, one education leader, and four teachers in each of the three locations. In New Mexico, the HS program was located on a Native …


Jangle Fallacy: Is Grit Distinct From Other Psychological Constructs?, Natasha Godkin Aug 2020

Jangle Fallacy: Is Grit Distinct From Other Psychological Constructs?, Natasha Godkin

Electronic Theses and Dissertations

This paper assessed the redundancy of the construct of grit (Crede, Tynan, Harms, 2017) compared to other similar constructs using structural equation modeling to remove the effect of measurement error. A series of models regressed grit and its subdomains (passion and perseverance of effort) on self-control, conscientiousness, achievement striving, and resilience. The R-squared values for these models ranged from 0.62 to 0.89. It is concluded that the concept of grit is mostly redundant with other constructs and is therefore an example of a Jangle fallacy (Kelley, 1927). The unique aspect of grit is mostly related to its passion …


A Case Study Of Civil War Environmental And Medical History Through The Disease Seasoning Of The 58th North Carolina Infantry Regiment In East Tennessee, Ashlie Richard Aug 2020

A Case Study Of Civil War Environmental And Medical History Through The Disease Seasoning Of The 58th North Carolina Infantry Regiment In East Tennessee, Ashlie Richard

Electronic Theses and Dissertations

This thesis is a case study aimed at a key argument in the emerging field of Civil War medical and environmental history. While historians have long acknowledged disease as a major killer during the Civil War, only recently have environmental and medical historians turned their collective attentions to unpacking the complex interconnections of disease, environmental conditions, and culture. By examining the 58th North Carolina Infantry Regiment from the mountains of western North Carolina, this thesis asserts that the combined role of the disease environment and conditions in military camps created the massive outbreaks of disease that characterized the seasoning …


The Lived Experiences Of Adolescent Ell Students In East Tennessee, Sarah Mould Aug 2020

The Lived Experiences Of Adolescent Ell Students In East Tennessee, Sarah Mould

Electronic Theses and Dissertations

Adolescent immigrant students face many challenges upon entering public schools for the first time, especially in rural areas where schools may not have the resources and cultural competence to meet their needs. Background factors like culture, previous schooling, and socioeconomic status combine with contextual factors in the learning environment, which further affect their academic outcome. The qualitative tradition of phenomenology was used to explore and describe the experiences and challenges of thirteen Spanish-speaking immigrant or newcomer youth who entered East Tennessee public middle or high schools within the last fifteen school years.

The findings indicated that parents’ perspectives and understanding …


A Mixed-Methods Analysis Of Abortion Attitudes And Perceptions Among Women Living In Alabama And South Carolina, Anthony Peluso Aug 2020

A Mixed-Methods Analysis Of Abortion Attitudes And Perceptions Among Women Living In Alabama And South Carolina, Anthony Peluso

Electronic Theses and Dissertations

Legal induced abortion is a safe option for terminating a pregnancy for women of reproductive age in the United States (U.S.), though access has varied since the Roe v. Wade and Doe v. Bolton cases in 1973. Information is lacking on women’s attitudes toward and perceptions of abortion as well as on related constructs such as pregnancy attitudes and contraceptive use. Exploring these constructs is important in that it can provide much needed context to women’s reproductive life planning. This research aimed to explore perceptions of abortion access and safety and examine the potential associations between attitudes toward abortion access …


Determining If Classroom Pets As Part Of An Empathy-Based Intervention Affect Public Elementary School Students’ Empathy, Randa Dunlap Aug 2020

Determining If Classroom Pets As Part Of An Empathy-Based Intervention Affect Public Elementary School Students’ Empathy, Randa Dunlap

Electronic Theses and Dissertations

The purpose of this mixed methods study was to determine if consistent exposure to classroom pets in public elementary school classrooms affected children’s empathy. The sample included 44 students (females = 22; males = 22; mean age = 8.3 years) from four third-grade classrooms. A pre-test, post-test design was used to measure students’ empathy levels, and percentage changes in empathy scores were recorded for all groups. The sample was a convenience sample, and random assignment to treatment groups was not possible. Treatment included using classroom pet fish along with empathy-based lessons. Of the four participating classrooms, one classroom was the …


Healthy Identity Development Among Black Same-Gender Loving Men: A Mixed Methods Approach, Byron D. Brooks Aug 2020

Healthy Identity Development Among Black Same-Gender Loving Men: A Mixed Methods Approach, Byron D. Brooks

Electronic Theses and Dissertations

Black Same-Gender Loving Men (BSGLM) are a population at the juncture of multiple marginalized identities, which may make it difficult to successfully form their identity due to experienced racism and heterosexism from communities to which they belong. Current paradigms of racial/ethnic and sexual identity do not fully capture the complexities of identity development among BSGLM. Moreover, there is scant literature available detailing what the process of identity development looks like among this population and which factors influence identity development among BSGLM. As such, the current study used an exploratory sequential mixed methods design to first discover what healthy identity looks …


Congruence And Temporal Variation Of Floral Visitation And Pollen Transport Networks In Southern Appalachia, Daniel A. Barker Aug 2020

Congruence And Temporal Variation Of Floral Visitation And Pollen Transport Networks In Southern Appalachia, Daniel A. Barker

Electronic Theses and Dissertations

Observation of floral visitation is an accepted method to describe plant-pollinator interactions despite potential biases. Collecting pollen from pollinators offers new insights on the structure and function of plant-pollinator communities. Furthermore, the strength and frequency of plant-pollinator interactions can vary across temporal scales. However, within-season and within-day (morning vs. evening) variation in plant-pollinator networks has been little studied. By evaluating variation in network structure across these biologically relevant time scales, we will gain a better understanding of the factors that shape plant-pollinator communities. The objectives of this study are to 1) Compare the structure of plant-pollinator networks built on floral …


Potential Toxicity Of Silver Nanoparticles To Microbial Communities And Macroinvertebrates, Joseph Kusi Aug 2020

Potential Toxicity Of Silver Nanoparticles To Microbial Communities And Macroinvertebrates, Joseph Kusi

Electronic Theses and Dissertations

Silver nanoparticles (AgNPs) are the most common nanomaterials incorporated in commercial products due to their antimicrobial activity. Recently, AgNPs were detected in surface waters suggesting the potential for bioavailability in the aquatic receptor organisms. This dissertation research attempts to understand the potential toxicity of AgNPs on water quality indicators, focusing on the microbial community and amphipods. This study evaluated whether: (1) the antimicrobial properties of AgNPs pose potential risks to microbial communities in pathogen impaired streams; (2) AgNPs can cause a shift in functional diversity and metabolic fingerprinting of microbial communities; (3) survival and growth of Hyalella azteca (amphipods) could …


Advanced Placement And Dual Enrollment Courses For Economically Disadvantaged Students And 2-Year Completion Rates At Tennessee Public Higher Education Institutions, Mia Hyde Aug 2020

Advanced Placement And Dual Enrollment Courses For Economically Disadvantaged Students And 2-Year Completion Rates At Tennessee Public Higher Education Institutions, Mia Hyde

Electronic Theses and Dissertations

The purpose of this study was to measure the possible relationship between Advanced Placement and dual enrollment courses for economically disadvantaged students on 2-year completion rates at public Tennessee higher education institutions. A quantitative, quasi experimental, comparative design was used to analyze secondary data to determine if there is a relationship between Advanced Placement, dual enrollment courses, and 2-year completion rates for students in Tennessee community colleges and public universities. The sample for this study consisted of students who entered a Tennessee community college or Tennessee public university in the Fall of 2015. These students had taken at least one …


Bdnf-Related Gene Expression Of Laser Capture Microdissected Glutamate Neurons From The Anterior Cingulate Cortex In Mouse Models Of Autism Spectrum Disorder, Misty Owens Aug 2020

Bdnf-Related Gene Expression Of Laser Capture Microdissected Glutamate Neurons From The Anterior Cingulate Cortex In Mouse Models Of Autism Spectrum Disorder, Misty Owens

Electronic Theses and Dissertations

Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting social behaviors. ASD affects 1 in 59 children with males affected more frequently. ASD is postulated to result from excitatory and inhibitory neurotransmission imbalances. Brain-derived neurotrophic factor (BDNF) signaling affects ASD by influencing synaptogenesis, plasticity, and survival. Studying early in-utero neuropathological changes within ASD requires the use of animal models. Expression of BDNF-associated genes were analyzed within laser capture microdissected pyramidal neurons from the anterior cingulate cortex of male and female BTBR and valproic acid mouse models. No expression differences were found in any gene comparing the three groups. Gender comparisons …


Negative Effects Of Coming Out As Lgbtq+ In A Non-Supportive Family, Ashley Nicole Hemphill Aug 2020

Negative Effects Of Coming Out As Lgbtq+ In A Non-Supportive Family, Ashley Nicole Hemphill

Electronic Theses and Dissertations

This study will explore the effects of coming out in a non-supportive family. The coming out process is when an individual discloses their sexual identity to another person. Coming out can be a wonderful experience for some or a negative life-changing moment. This interpretive phenomenological study examined the patterns and themes found through four extensive interviews. The four participants recruited through social media and flyers participated in an interview where they were asked questions about their coming out experience. The minor common themes were experiences by three out of the four participants. These minor common themes were failed parenting, coming …


The Economics Of Love, Débora Silva Viana Aug 2020

The Economics Of Love, Débora Silva Viana

Electronic Theses and Dissertations

In this thesis I argue that the obligation to love based on the Christian tradition requires Christians to disperse their resources in a way that significantly evens out wealth distribution and increases social justice. Christians disagree on the terminology and some tenets of the goal of the Christian life (e.g., deification, beatific vision, communion with God, salvation). However, the requirement to practice love is common to all of these concepts, thus making love normative for Christians. I argue that when love takes such a prominent role in one’s life, then it naturally influences how one manages one’s resources. If love …


Implicit Bias And Voluntarily Childfree Adults, Virginia Elizabeth Powell Aug 2020

Implicit Bias And Voluntarily Childfree Adults, Virginia Elizabeth Powell

Electronic Theses and Dissertations

This quantitative study aimed to determine if there is a negative bias towards voluntarily childfree adults or an association of negative views and attitudes with voluntarily childfree adults, controlling for other participant characteristics such as race, religion, or sexual orientation. At this stage in the research, voluntarily childfree adults are generally defined as legal adults who have the intention to remain childfree for the rest of their lives, due to reasons other than fertility issues. A negative view or bias is defined as any attitude which is not a desirable interpretation of behavior or lifestyle. A negative bias against voluntarily …


Do Muslims And Christians Worship The Same God: A Philosophical Approach, Zachary W. Casey Aug 2020

Do Muslims And Christians Worship The Same God: A Philosophical Approach, Zachary W. Casey

Electronic Theses and Dissertations

In this thesis I probe the question of whether Muslims and Christians worship the same God primarily through the discipline of philosophy of language. Though a multifaceted question at its core (e.g., theological, historical), the question directly ties into how language operates in relation to God. That is, the ways in which Muslims and Christians make predications of God have a significant role in delineating whether they worship the same God. By working from the perspective of predication, I argue that Muslims and Christians refer to but do not worship the same God. In this sense, Muslims and Christians refer …


Psychopathy Assessment And Related Constructs: Differences And Distinctions For Primary And Secondary Psychopaths, Simon Saleem Aug 2020

Psychopathy Assessment And Related Constructs: Differences And Distinctions For Primary And Secondary Psychopaths, Simon Saleem

Electronic Theses and Dissertations

This study investigated the assessment of psychopathy from the perspectives of two self-report scales that differ substantially their construction and conceptual approach to the fundamental clinical subtyping of psychopaths: primary versus secondary psychopathic presentations. The self-report scales used in this study were the Levenson Self-Report of Psychopathy Scale (LSRP; Levenson et al., 1995) and the Perkins’ Alienation Scale-Short Version (PAS; Perkins & Harper, 1998). It was hypothesized that the presence of psychopathy would demonstrate significant presence in the distribution of undergraduate students and additionally, that these measures would demonstrate construct validity and replicate previously established relationships between psychopathy measures and …


Food Security As A Basic Right For College Students: A Descriptive Study Of The Factors Associated With Food Insecurity And Higher Education Attainment, Shannon Beatrice Que Aug 2020

Food Security As A Basic Right For College Students: A Descriptive Study Of The Factors Associated With Food Insecurity And Higher Education Attainment, Shannon Beatrice Que

Electronic Theses and Dissertations

Food insecurity amongst college students is a rising crisis. Students’ inability to access nutritional food on a consistent basis can negatively impact student retention, academic success, mental and physical health, and social mobility, all of which are at an even greater risk due to the rise of the COVID-19 pandemic. Additionally, children and adolescents in primary and secondary school who experience food insecurity can experience developmental delays, which can impede their ability to obtain a postsecondary degree. Limited research has been conducted on the topic of food insecurity at private universities as well as identifying chronic food insecurity. The present …


Church And Public School Partnerships Creating Educational Equity, Michael L. Patterson Aug 2020

Church And Public School Partnerships Creating Educational Equity, Michael L. Patterson

Electronic Theses and Dissertations

Abstract

The problem of this study involved how pastors can enhance their awareness of creating church and public school partnerships, the contributing factors that prevent the formation of public school and urban church partnerships, and the need to identify leadership strategies that can be implemented by school leaders and urban pastors to overcome those obstacles. The purpose of this qualitative case study was to investigate how urban pastors and public-school leaders could become more aware of church and public-school partnerships and address contributing factors that prevent church and public school partnerships. In addition, possible leadership strategies to increase church and …


Protecting Healthcare Workers From Violence, Terry L. Taylor Aug 2020

Protecting Healthcare Workers From Violence, Terry L. Taylor

Electronic Theses and Dissertations

Growing violence in the community increases the risks of injuries to healthcare workers. This project assessed the levels of emotional exhaustion, depersonalization, and acknowledgment of professional accomplishments in healthcare workers in the community who were responsible for the care of confused and combative clients. The community healthcare workers were assessed using the Maslach Burnout Inventory-Human Services Survey-Medical Personnel. An intervention was then presented, which focused on self-awareness, including mood assessments, soothing rhythmic breathing, compassionate focused imagery, and the creation of a safe place to process criticism compassionately. The participants were resurveyed after 30 days by repeating the Maslach Burnout Inventory-Human …


Thriving On A Faith-Based Campus: An Exploratory Study On Sense Of Belonging, Spirituality, And The Student Experience For Students Of Color, Hannah Felice Aug 2020

Thriving On A Faith-Based Campus: An Exploratory Study On Sense Of Belonging, Spirituality, And The Student Experience For Students Of Color, Hannah Felice

Electronic Theses and Dissertations

While enrollment for students of color has increased by nearly 15% over the past 20 years, universities have struggled to retain and graduate students of color in comparison to their White peers, including Christian universities. Looking to foster success for all students, higher education has sought to better understand the factors that impact student retention and graduation, particularly for students of color. Thriving has been shown as an effective metric for understanding the student experience through a more holistic framework as it pertains to the student success. The purpose of this study is to explore the concept of thriving as …


A Needs Assessment: Exploring The Unknown Needs Of The Homeless Unaccompanied Youth Within A West Texas Independent School District, Amy Grace Weiss Aug 2020

A Needs Assessment: Exploring The Unknown Needs Of The Homeless Unaccompanied Youth Within A West Texas Independent School District, Amy Grace Weiss

Electronic Theses and Dissertations

ABSTRACT This exploratory study aims to explore the unknown needs among the unaccompanied youth population within a small urban community in West Texas. This cross-sectional study surveyed a convenience sample of 10 unaccompanied youth attending school within an independent school district. Data were collected using a social worker’s case load during the spring semester of 2020, during the COVID-19 global pandemic. Findings showed a certain level of need within this community, such as emergency shelters and further research on food insecurity for this population. This implies the need for practice and policy on multiple levels to help this population who …


Impact Of A Diversion Program On Mentally Ill Inmates In A County Jail System, Janet Lawler Aug 2020

Impact Of A Diversion Program On Mentally Ill Inmates In A County Jail System, Janet Lawler

Electronic Theses and Dissertations

ABSTRACT The United States incarcerates more people in correctional facilities than any other country in the world. Studies show 15% of the prison populations have a mental illness diagnosis and 20% of local jail populations have a mental illness diagnosis. These individuals are often arrested because of a misdemeanor crime committed as a direct result of their diagnosis; however, instead of receiving mental health services they are taken into custody, further damaging an already tenuous existence. Traditionally, correctional facilities are geared toward punishment and protection of society, not treatment of mental illness and rehabilitation. Recent trends see a combination of …


Qualifications Of Executive Nurses For Service On Hospital Boards, Michelle Lee Foxx Aug 2020

Qualifications Of Executive Nurses For Service On Hospital Boards, Michelle Lee Foxx

Electronic Theses and Dissertations

Abstract Healthcare governing boards have responsibility for the legal and financial stability of the organization. They are assuming more responsibility for quality care and outcomes. Nurse leaders have valuable insights into key shared governance issues such as quality of care, financial performance, legal requirements, and regulatory oversight. Yet, only 5% of the 3.2 million nurses in the U.S. health workforce hold a seat on hospital governing boards in the United States. The purpose of this study was to explore how nurses with executive experience perceive their own leadership qualities in the context of established requirements for executive hospital boards. Fifty …


Land Suitability Analysis For Windfarm Development In Texas, Robert Laszlo Milecz Aug 2020

Land Suitability Analysis For Windfarm Development In Texas, Robert Laszlo Milecz

Electronic Theses and Dissertations

Due to the negative impact on the environment of conventional electric power generation methods, especially coal and oil-fired generating plants, wind power as an alternative for sustainable energy has received more attention in recent years. The purpose of this project was to apply Geographic Information System (GIS), integrated with Multi Criteria Decision Making (MCDM), for identifying suitable areas for wind turbine applications in Texas. Factors taken into consideration included socioeconomic criteria such as distance to highways, proximity to airports and urban areas, localized environmental criteria such as terrain slope and distance to rivers, affected waterbodies, and wildlife management areas. Also …