Digital Commons Network^™

Examining Overrepresentation In Special Education Amongst African Americans Diagnosed With Emotional Disturbance In The State Of Pennsylvania, Krisa Franzetta

Electronic Theses and Dissertations

This study examines the disproportionality in special education, regarding African American students being overrepresented, specifically under the disability category of Emotional Disturbance (ED) within the state of Pennsylvania. Demographic information was collected with the use of secondary data provided by the Pennsylvania Department of Education, using 648 educational programs across 29 intermediate units. Data were analyzed with statistical representation of percentages as related to risk composition and the E-Formula. The results yielded an average risk of African American students being two times more likely to be diagnosed with ED than their White peers. Additional results from the calculation of the …

Genomic Analysis And Metabolic Potential Of Myxobacteria, Hanan Albataineh

Electronic Theses and Dissertations

Myxobacteria are known for their large genomes that bestow them with a distinct lifestyle that is characterized by fruiting body formation, gliding motility, social interactions, predation, and secondary metabolite production. The powerful combination of whole-genome sequencing and bioinformatics-driven analysis of sequence data has delivered unexpected insights into myxobacterial microbial communities. We applied these two approaches to investigate the chemical space and biosynthetic potential of myxobacteria. Mining different myxobacterial genomes for biosynthetic gene clusters led us to the discovery of a cryptic acyl-homoserine lactone (AHL) synthase encoded in the genome of the myxobacterium Archangium gephyra. Bioinformatic analysis of this AHL synthase …

Chasing The Light, Nadia Alexis

Electronic Theses and Dissertations

Chasing the Light is a young adult novel-in-verse is a 16-year-old Haitian American teen photographer and survivor of dating violence who is a lover of myth and folklore, who is good at keeping secrets, and who is hungry for freedom. Her parents want her to follow the traditional path of going to college and pursuing a well-paying career like becoming a lawyer or a doctor. She wants to be free to uncover truths about her newly single self and to make her mark as a young artist aspiring to go to college to study photography so she could become a …

Evaluating The Effects Of Thermal Cycling On Bone (Cold-Blooded Vs Warm-Blooded), Parker Reed Brewster

Electronic Theses and Dissertations

Thermal cycling, a global threat that is increasingly becoming more real, is a stressing event that can drastically change material properties. Thermal cycling can be used for material strengthening and optimization, but more often than that, thermal cycling is a nuisance that weakens the integrity of structures and coatings. To understand and build better designs that resist the effects of thermal cycling, we look to nature. Though warm-blooded animals regulate their body temperatures within an exceptionally tight range, cold-blooded animals experience relatively extreme temperature fluctuations, and oftentimes, in less than a 5-hour time period. In other words, cold-blooded animals experience …

The Self Compassionate Side Of Awe: The Relationship Between Awe And Self-Compassion Via Self-Diminishment And Connectedness, Rachael Marie Cavallaro

Electronic Theses and Dissertations

Given that having a self-compassionate attitude is linked to positive psychological functioning, it is important to identify factors that promote self-compassion. Several self-transcendent experiences and emotions, which perceptually blur the lines between the self and others, predict self-compassion. Awe, a mixed-valance emotion defined by vastness and need for accommodation, seemed a likely candidate to promote self-compassion, as it is also a self- transcendent emotion with intra and interpersonal functions (e.g., increased humility, openness, and connection) that theory and empirical research has linked to self-compassion. Thus, we hypothesized that awe would promote self-compassion both directly and indirectly via boosted feelings of …

Design And Fabrication Of Additively Manufactured Arm Cast Using Topology Optimization, Tereza Janatova

Electronic Theses and Dissertations

The traditional approach to casting non-operative arm fractures involves fully covering a large portion of the forearm, often including a portion of the palm. The use of gypsum plaster and plaster materials often results in cutaneous problems or in more severe cases swelling, pressure sores, or deep vein thrombosis. Other disadvantages include the weight, time it takes to harden, or the damage in contact with water. The objective of the project is to create a durable but breathable custom-made design for an arm brace that will replace the traditional solutions by overcoming their disadvantages. Several research groups and companies provide …

Empirical Essays In Law And Economics, Bright Addiyia Osei

Electronic Theses and Dissertations

I examine the effect of laws and policies regulating the use of drugs onthe decision making of economic agents. In the first paper, I estimate the effects of legalized recreational marijuana on entry into the foster-care system by exploiting state-level variation in legalization and its timing, I estimate that legalization decreases foster-care placements by at least 10%, with larger effects in years after legalization. I find even larger decreases in admissions due to parental drug and alcohol abuse, implying that substitution towards marijuana from other substances is an important part of how legalization affects admissions. I find similar effects for …

Emotion Regulation In Migraine, Tracy Protti

Electronic Theses and Dissertations

Migraine is the third most common medical condition across the globe and a leading cause of years lived with disability due to its considerable burden. The burden is further compounded by the high prevalence of psychological comorbidities and the influence of other psychological factors on functioning. Examinations of migraine within the fear-avoidance model suggest that fear of pain (FOP) promotes maladaptive avoidance and escape behaviors, which contribute to headache-related disability. Limited research demonstrates that those with migraine engage in avoidant emotion-regulation (ER) strategies but has overlooked ER abilities beyond acceptance. The current study aimed to investigate ER in individuals with …

Protein Redesign And De Novo Design Approaches To Create Artificial Nickel-Dependent Metalloenzymes, Dhanashree Selvan

Electronic Theses and Dissertations

Energy crisis, energy demand and climate change are the major challenges of this century. As we face these challenges, it’s important that we depend on alternate energy forms like renewable energy sources and at the same devise ways to tackle the greenhouse effect. Therefore, it is important to move towards a carbon neutral energy economy where we can convert atmospheric carbon dioxide back into organic carbon and depend on clean energy sources like Hydrogen. These energy concerns can be tackled well if we understand the role of enzymes responsible for various biological reactions.Metals play a variety of unexpected roles in …

Bridging Souths: Interdisciplinarity And Knowledge Production In Southern Studies, Matthew David Streets

Electronic Theses and Dissertations

This thesis examines the viability of southern studies, a regional studies project on the study of the U.S. South, as an academic field of study and institutionalized site of multi-, inter-, and transdisciplinary knowledge production. Southern studies has undergone numerous turns and paradigm shifts since its institutionalization in the 1970s. These ontological, epistemological, and methodological developments have reoriented the objectives of interdisciplinary knowledge production. Despite the present permeability of disciplinary boundaries, the institutional structure and its racial, capitalist, and disciplinary hierarchies hinder communication and collaboration across disciplines and fields and between the “ivory tower” and “real world.” Understanding the impact …

Do Individuals With Functional Gastrointestinal Symptoms Experience Emotions Differently? An Examination Of Emotional Responding During A Series Of Emotion Induction Tasks, Sara Witcraft

Electronic Theses and Dissertations

Functional gastrointestinal disorders (FGIDs) are disorders of the brain-gut axis characterized by physiological and emotional disturbances, including heightened comorbidity with psychiatric disorders. Individuals with FGIDs experience difficulties with emotional processing, including the awareness, identification, and regulation of emotions. Although emotional processing is implicated in the maintenance and exacerbation of FGID pathology, literature examining these associations is limited. The current study aimed to enhance understanding of the emotional processing of individuals with FGIDs. We recruited individuals with and without FGID symptoms and examined the: (1) association between gastrointestinal distress and psychopathology; (2) association between gastrointestinal distress and emotional and physiological responsivity; …

Our Bodies, Our Stories: Mental And Physical Self Connection As A Protective Factor In Sexual And Gender Minorities, Emerson A. Todd

Electronic Theses and Dissertations

The mind and body connection has been actively examined in neuroscience and developmental psychology backgrounds. Sociological theorists posit ways that individuals develop a sense of self through mind, body, and the social world. While research on the connection between the mind and body in disabled and aging populations is common, less is known of the everyday impact of these connections for other minority populations. The present study uses mixed-methods research to explore the relationship between mind and body and the impacts on internal and social life. The quantitative aspect of the study found significant relationships between physical and mental health …

Educator Perceptions Of The Working Environment In Tennessee Elementary Schools That Actively Employ Positive Behavior Supports And Restorative Practices, Scott Thomas Lamie

Electronic Theses and Dissertations

This phenomenological study captured the experiences of elementary educators with the purpose of gathering their perceptions of the use of restorative practices and positive behavior supports in their schools with a particular focus on how these programs influenced school climate, their professional efficacy, and their job satisfaction. Results of interviews lead to the emergence of seven major themes, which were the importance of understanding the underlying causes of student behavior, change, common practices of positive behavior supports and restorative practices, benefits for students, benefits for educators, struggles with implementation, and suggestions for implementation. These findings led to the identification of …

Overview Of Transition Care Clinics And Patient No-Shows, Manul Awasthi

Electronic Theses and Dissertations

Introduction

Transition care clinics (TCCs) have proven to be effective in meeting the time-sensitive needs of patients in the post-discharge period and ensuring smooth transitions of patients from hospital to home. These clinics have led to lower readmissions, lower emergency department visits, cost savings, and lower rates of other adverse events following discharge. However, TCCs, including the East Tennessee State University Family Medicine (ETSU-FM) TCC have been facing high rates of patient no-shows.

Aim

The aim of this dissertation is to identify the different components and outcomes of TCC based on the literature. We further aim to analyze the TCC …

Community Structure Analysis Of Turtles With Application To The Early Pliocene Gray Fossil Site, Julian Conley

Electronic Theses and Dissertations

Turtles are important components of ecosystems around the world, with diverse ecological niches and adaptations. However, there are few detailed studies of how turtle community structure reflects local environments. This project applied techniques of community structure analysis to sites across the United States to infer past ecosystem and environmental conditions of the early Pliocene Gray Fossil Site (GFS) in northeastern Tennessee based on the ancient turtle community. Results indicate extant turtle community structure closely reflects environmental conditions, and that ancient turtle communities can be used to infer climate and habitat conditions of past ecosystems. Application to the GFS turtle community …

An Investigation Into The Use Of Biomechanical And Performance Data From Vertical Jump Testing To Monitor Competitive Weightlifters, Dylan Suarez

Electronic Theses and Dissertations

This investigation aimed to employ novel analyses to longitudinal jump testing data gathered from competitive weightlifters to identify how certain biomechanical and performance characteristics obtained from the countermovement jump (CMJ) relate to changes in weightlifting performance over time and if they can differentiate higher and lower performers. A linear mixed-effect model was used to assess and compare the ability of countermovement jump height and net-impulse to predict Sinclair weightlifting total. CMJ force-time waveforms were compared in cross-sectional and repeated measures analyses to distinguish the force application patterns of higher-performing weightlifters and if they change over extended periods of training. It …

Performance Cultures And Black Atlantic Literature, 1750-1833, Chinaza Amaeze Okoli

Electronic Theses and Dissertations

This dissertation approaches performance cultures as integral components of early black Atlantic writing, and considers how meaning is produced at the intersection of writing and vernacular performance. It asserts that black writers, in their portrayal of performance practices, encode avenues and strategies for accessing other black voices in their communities. Pairing writing by black authors and a selection of comparable vernacular practices, my dissertation examines how these forms signify upon each other, offering new contexts for interpreting the black experience in the long eighteenth century. In exploring this thesis, my work approaches Olaudah Equiano’s narrative as illustrative of the ways …

Donor-Acceptor (D-A) Type Semiconducting Materials For Optoelectronic Applications, Tharindu Ranathunge

Electronic Theses and Dissertations

The need for intrinsically conducting polymers (ICPs) in industrial applications such as microchips, capacitors, organic solar cells, and printed electronics is wide-ranging and ever-growing. Among many methods to synthesize ICPs, electropolymerization has become a convenient method for creating and characterizing complex organic copolymers having intrinsic electronic conductivity, including the donor (D)-acceptor (A) class of electronically conducting polymers. Electrochemical analysis has proven the unique redox properties of these polymers as thin films. Specifically, ICPs comprised of electron-rich D and electron-deficient A moieties have been shown to possess intrinsic electronic conductivity and unique optical and electronic properties. Herein, we discuss the design, …

Investigating The Relationships Between Socioeconomic Status, Kratom Legislation, And The Covid-19 Pandemic On Opioid Overdose Mortality In The United States., Lyndsey Blair

Electronic Theses and Dissertations

Background: 585,000 people have died from an opioid overdose in the US between 1999 and 2020. The current opioid epidemic has been described as a quadruple wave of overdoses, due in part to the changes in prescription and illicit opioid supply as well as the underlying social and structural factors that led to a subsequent increase in demand. In order to mitigate the opioid epidemic through prevention and protection strategies, we must first understand the social and structural factors that are driving the increase in opioid misuse and abuse. To better understand the socioeconomic factors, we described socioeconomic profiles of …

Tobacco-Derived Aldehydes, Platelets, And Thrombogenicity: Role Of Transient Receptor Potential Ankyrin-1., Andre D. Richardson

Electronic Theses and Dissertations

Cardiovascular disease (CVD) remains the world’s leading cause of morbidity and mortality. Conventional smoking of tobacco cigarettes is the number one risk factor for onset of CVD. Active cigarette users as well as those individuals who are exposed to second-hand cigarette smoke are at increased risk of CVD. Studies have shown that conventional smoking significantly increases a user’s risk of thrombosis, atherosclerosis, peripheral arterial disease, and coronary artery disease. Any of these diseases may trigger myocardial infarctions, stroke, or hypertension that may lead to cardiovascular morbidity and mortality. New and emerging electronic nicotine delivery systems (ENDS), such as electronic cigarettes …

Stromal Vascular Fraction Restores Vasodilatory Function By Reversing Mitochondrial Dysfunction And Oxidative Stress In Aging-Induced Coronary Microvascular Disease., Evan Paul Tracy

Electronic Theses and Dissertations

Background: Coronary Microvascular Disease (CMD) presents in aging post-menopausal women with chronic angina due to microvascular hyperconstriction. The objective was to identify mechanisms of adipose stromal vascular fraction’s (SVF) restorative effects on vasodilation. We hypothesize aging-induced CMD is caused by a) abrogated flow-mediated dilation (FMD) due to loss of nitric oxide signaling and b) ROS-dependent βADR desensitization & internalization, reversible by ameliorating mitochondrial dysfunction and oxidative stress with SVF. Methods: Coronary microvessels were isolated from female rats either young, old, or old with SVF tail-vein injection (OSVF). Pressure myography, RNA-sequencing, immunofluorescence, Western blotting, and morphological analysis were performed to …

Solving The Challenges Of Concept Drift In Data Stream Classification., Hanqing Hu

Electronic Theses and Dissertations

The rise of network connected devices and applications leads to a significant increase in the volume of data that are continuously generated overtime time, called data streams. In real world applications, storing the entirety of a data stream for analyzing later is often not practical, due to the data stream’s potentially infinite volume. Data stream mining techniques and frameworks are therefore created to analyze streaming data as they arrive. However, compared to traditional data mining techniques, challenges unique to data stream mining also emerge, due to the high arrival rate of data streams and their dynamic nature. In this dissertation, …

A Computational Model Of The Line-1 Retrotransposon Life Cycle And Visualization Of Metabolic Networks In 3-Dimensions., Michael D. Martin

Electronic Theses and Dissertations

Computational modeling of metabolic reactions and cellular systems is evolving as a tool for quantitative prediction of metabolic parameters and reaction pathway analysis. In this work, the basics of computational cell biology are presented as well as a summary of physical processes within the cell, and the algorithmic methods used to find time dependent solutions. Protein-protein and enzyme-substrate interactions are mathematically represented via mass action kinetics to construct sets of linear differential equations that describe reaction rates and formation of protein complexes. Using mass action methods, examples of reaction networks and their solutions are presented within the Virtual Cell simulation …

Bayesian Methodologies For Constrained Spaces., Siddhesh Kulkarni

Electronic Theses and Dissertations

Due to advances in technology, there is a presence of directional data in a wide variety of fields. Often distributions to model directional data are defined on manifold or constrained spaces. Regular statistical methods applied to data defined on special geometries can give misleading results, and this demands new statistical theory. This dissertation addresses two such problems and develops Bayesian methodologies to improve inference in these arenas. It consists of two projects: 1. A Bayesian Methodology for Estimation for Sparse Canonical Correlation, and 2. Bayesian Analysis of Finite Mixture Model for Spherical Data. In principle, it can be challenging to …

Barriers And Opportunities To Sustainable Urban Agriculture: The Case Of Louisville, Kentucky., Sait Sarr

Electronic Theses and Dissertations

As the urban populations continue to increase, food insecurity will continue to affect urban residents as well, depriving them of access to abundant and nutritious food. This has captured the attention of many policymakers, urban planners, nonprofits, grassroots movements, and other stakeholders. As a result, there is growing interest in developing new sustainable strategies and policy measures that improve food security through the promotion of sustainable urban agriculture. More than 100,000 Louisville residents, of which 20% are from West Louisville, do not have access to adequate and nutritious foods, and are at a higher risk of developing health issues. West …

Quality Of Life And End-Of-Life Plans: The Inclusion Of Sexual Health., Jacinta Dickens

Electronic Theses and Dissertations

Sex and intimacy are important components of quality of life (Syme, 2014). Previous research found a positive relation between quality of life and sexual satisfaction (Chao et al., 2011), but how this relation may or may not impact end-of-life plans was unexplored. This study explored if the relation between quality of life and sexual satisfaction determined if community-dwelling middle-aged or older adults in the US have or was willing to incorporate sexual health within their formal or informal end-oflife plan. Correlation analyses examined cross-sectional survey data. Findings revealed a statistically significant correlation between quality of life and sexual satisfaction, no …

Effects Of Monovalent And Divalent Ions In Factor Xiii Activation And Crosslinking., Richard Laporca Lumata

Electronic Theses and Dissertations

Factor XIII (FXIII) is an emerging target for treating blood clotting and cardiovascular related diseases. FXIII can be activated non-proteolytically by the presence of elevated Ca²⁺ levels (2-100 mM) or proteolytically by thrombin-cleavage of the Activation Peptide along with low mM Ca²⁺. The studies herein utilized fluorescence to examine how monovalent and divalent ions influence the transglutaminase activity and conformation of FXIII. Monodansylcadaverine assays revealed that increasing ionic radius (Cs⁺ > K⁺ > Na⁺ > Li⁺) and increasing ionic strength (XCl^- levels and SO₄^2- > Cl^-) elevated FXIII-A transglutaminase activity. Intrinsic …

Not Only Black Or Only A Woman, A Black Woman: Gendered Racial Microaggressions, Colorism And Hair On Trauma Symptoms., Maame-Safowaa Geary

Electronic Theses and Dissertations

The intersectionality of racism and sexism of Black women has the possibility of leading to mental health symptoms due to the consistent and persistent experience of insidious trauma, specifically gendered racial microaggressions (GRM). In this study, we examined the relations between gendered racial microaggressions (GRM) and trauma/PTSD symptoms, depressive symptoms, and anxiety symptoms among Black women. Additionally, skin tone and hair style/texture were explored as moderating variables. We hypothesized a positive relation between GRM and symptoms of trauma/PTSD, depression, and anxiety. We also hypothesized that darker skin tones and more Afrocentric hairstyles would moderate GRM and the described mental health …

“I Don' Want To Upset Anyone - I Just Want To Exist": Nonbinary College Student Experiences At A Public Mid-Southern University., Cat Renee Alexander

Electronic Theses and Dissertations

This study analyzed the experiences of twenty-four nonbinary students at Sunnydale University, using a grounded theoretical approach with a standpoint perspective. Snowball sampling, e-mail advertising, and poster advertising were utilized. Themes and findings came from two areas, those of contrasting experiences and those of consensus opinions. Participants had contrasting experiences based on gender, pronouns, race/ethnicity, student classification, and major. Consensus opinions include suggested changes for campus inclusiveness that many participants discussed. A pre-interview survey was used to filter participants and collect demographic information and then interviews were collected from August 2021 – December 2021. This study found that although Sunnydale …

Unraveling Dna And Identity: A Humanistic Perspective On Epistemologies And Ethics Of Genetic Ancestry Testing., Eve Carlisle Polley

Electronic Theses and Dissertations

The advent of DNA ancestry testing motivated a burst of human activities that constitute a scientific-technological-industrial-personal-social movement of immense scale, infused with epistemological and ethical questions of great and important variety. This movement has motivated many discourses in the social sciences, with study subjects ranging from the language usage of geneticists, to moral conundrums faced by test-takers, to potential ramifications in global structures of political power. At the same time, and especially in recent decades, the discourses of the comparative humanities have included with increasing frequency and urgency research and theorization about concepts and consequences of human social identities, alongside …