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Articles 11041 - 11070 of 35665
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Short Stories., Karley Miller
Short Stories., Karley Miller
Electronic Theses and Dissertations
My creative thesis consists of a number of short stories. Each individual story stands alone, though all pieces in the project are doubtless connected by setting and syntax. Perhaps due to my own lack of imagination the stories take place, at least to some extent, in a small town. Though this may not be made explicit in every story, it can be deduced. Small town life, and particularly small town folk, are of interest to me; they are also what I know best. For example, Tom of “Neighbors” is a man living in a small town. The old man next …
Spontaneous Vocal Matching In Mothers And Their Hearing Impaired Infants With Cochlear Implants : A Quantitative Analysis., Lydia Doggett
Spontaneous Vocal Matching In Mothers And Their Hearing Impaired Infants With Cochlear Implants : A Quantitative Analysis., Lydia Doggett
Electronic Theses and Dissertations
Vocal matching, the ability to imitate phonetic properties of speech, was examined in spontaneous interactions of sixteen dyads of mothers and their hearing-impaired (HI) infants with cochlear implants and age-matched normal-hearing (NH) infants. Mother-infant dyads came to three sessions at three, six, and 12 months post-implantation. Vocal matching was defined as an instance of perceptual and acoustic similarity of vowels and consonants between adjacent maternal and infant utterances. Vocal matching occurred in 25% to 50% of infant and in 17% to 64% of mother vocalizations across dyads. Both mothers and infants in the HI group produced fewer matches as compared …
The Cultural Creation Of Fulvia Flacca Bambula., Erin Leigh Wotring
The Cultural Creation Of Fulvia Flacca Bambula., Erin Leigh Wotring
Electronic Theses and Dissertations
This study presents a scholarly and popular historiography of Fulvia Flacca Bambula with criticism of the presentation and interpretation of Fulvia as a historical character in context. Source bias caused by Augustan propaganda is widely recognized within scholarly and popular treatment of Fulvia but little attention is given to the influence of rhetoric and moral philosophy on the invective and anecdotal narratives used as source evidence in discussion of Fulvia as a Roman matron. Through assessment of traditional Roman rhetorical and literary conventions employed during the late Republican and early Imperial periods with attention to the influence of elegiac constructs …
Sonic Intolerance : Aural Yellowface During The Golden Age Of American Radio., Greyson Perry Neff
Sonic Intolerance : Aural Yellowface During The Golden Age Of American Radio., Greyson Perry Neff
Electronic Theses and Dissertations
The position of the Asian in the American popular imagination has a long history, stretching back to nineteenth century vaudeville theatrical performances and remaining largely unchanged throughout the twentieth and into the twenty-first century. Portrayed as simultaneously cunning and ignorant, spiritual and corrupt, or submissive and sexualized, Oriental stereotypes have remained firmly entrenched in popular culture. While perceptions of race exist largely in a visual sense, a closer look at how people heard racial differences opens up new avenues for scholarly interpretation of the social construction of race and the shifting notions of citizenship. This thesis will investigate how listeners …
A Curriculum Of Civic Responsibility : Transitioning Black American Students To College-Level Writing., Jamila M. Kareem
A Curriculum Of Civic Responsibility : Transitioning Black American Students To College-Level Writing., Jamila M. Kareem
Electronic Theses and Dissertations
This dissertation considers how racialized differences educational experience transition with Black students as they perform the expectations of college writing curriculum. I address the question: in what ways can a first-year writing curriculum centered on civic responsibility aid in smoother transitions from secondary to postsecondary academic writing for Black students at predominantly White institutions? My study applies racial and critical race methodologies framed within the tenets of critical race theory, institutional whiteness, and the absent presence of race in composition studies. I apply the methodologies in three key ways: analyzing transition practices through racialized perspectives; evaluating general education writing curriculum …
Enhancing Cell Therapy For Ischemic Cardiomyopathy., Michael J. Book
Enhancing Cell Therapy For Ischemic Cardiomyopathy., Michael J. Book
Electronic Theses and Dissertations
Cardiac cell therapy using cardiac mesenchymal cells (CMC) significantly reduces ventricular dysfunction in patients with ischemic cardiomyopathy. Despite the improvement in function, a modest number of CMCs survive in the heart post-transplantation. In this study, we sought to improve the survival and retention of transplanted CMCs to prolong the therapeutic benefits afforded by cardiac cell therapy. To do this, we targeted the enzyme telomerase (TERT), known to be active in some highly proliferating cells (e.g. germ, stem). TERT is responsible for preventing telomere attrition, thereby allowing continued proliferation. TERT has also been shown to be protective, improve cell migration and …
Low-Resolution Adc Receiver Design, Mimo Interference Cancellation Prototyping, And Phy Secrecy Analysis., Chen Cao
Electronic Theses and Dissertations
This dissertation studies three independent research topics in the general field of wireless communications. The first topic focuses on new receiver design with low-resolution analog-to-digital converters (ADC). In future massive multiple-input-multiple-output (MIMO) systems, multiple high-speed high-resolution ADCs will become a bottleneck for practical applications because of the hardware complexity and power consumption. One solution to this problem is to adopt low-cost low-precision ADCs instead. In Chapter II, MU-MIMO-OFDM systems only equipped with low-precision ADCs are considered. A new turbo receiver structure is proposed to improve the overall system performance. Meanwhile, ultra-low-cost communication devices can enable massive deployment of disposable wireless …
Sight-Singing Pedagogy : A Survey Of High School Choral Directors., Marissa Lee Pollock
Sight-Singing Pedagogy : A Survey Of High School Choral Directors., Marissa Lee Pollock
Electronic Theses and Dissertations
The purpose of this study was to highlight effective sight-singing techniques used by successful choral directors in the state of Kentucky. The method used for this study was a non-experimental survey sent to thirty-four high school choral directors. Directors were selected to participate based on distinguished assessment scores received over the last five years (2011-2015). They were asked questions about their techniques, background in education, and placement of sight-singing in the curriculum. With a response rate of 65% the results indicated that the majority of directors had received or earned at least a master’s degree, had taught for at least …
Data Driven Discovery Of Materials Properties., Fadoua Khmaissia
Data Driven Discovery Of Materials Properties., Fadoua Khmaissia
Electronic Theses and Dissertations
The high pace of nowadays industrial evolution is creating an urgent need to design new cost efficient materials that can satisfy both current and future demands. However, with the increase of structural and functional complexity of materials, the ability to rationally design new materials with a precise set of properties has become increasingly challenging. This basic observation has triggered the idea of applying machine learning techniques in the field, which was further encouraged by the launch of the Materials Genome Initiative (MGI) by the US government since 2011. In this work, we present a novel approach to apply machine learning …
Pediatric Anxiety And/Or Depression Problems : Associations With Pm10, Fly Ash, And Metal Exposure., Abby Nicole Burns Hagemeyer
Pediatric Anxiety And/Or Depression Problems : Associations With Pm10, Fly Ash, And Metal Exposure., Abby Nicole Burns Hagemeyer
Electronic Theses and Dissertations
Background: In the last several decades, the use of coal has become more prevalent in turn increasing the amount of coal ash being produced. Coal ash, the by-product of coal combustion, is composed of small particles that contain essential elements, hazardous metals, polycyclic aromatic hydrocarbons, and radioactive material. While a small proportion of coal ash is reused, the majority gets discarded in open-air landfills and ash ponds. Fly ash, the major component of coal ash, can become emitted into the air and potentially contribute to the air pollution and metal exposure in the surrounding community. Few studies, particularly in the …
Dead Places : American Horror, Placelessness, And Globalization., Katherine Ashley Wagner
Dead Places : American Horror, Placelessness, And Globalization., Katherine Ashley Wagner
Electronic Theses and Dissertations
This dissertation investigates particular American anxieties concerning cultural identity and place, particularly fears about America’s place (or lack thereof) within the global world, that can be seen throughout much of post-WWII American horror literature and film. More specifically, this project explores how an existent pattern of visual and narrative depictions of destroyed bodies and places illustrates larger tensions and fears about placelessness—the affect and effect of incomplete, partial, or inauthentic relationships with the places that provide cultural and individual identity and meaning. I argue that representations of placelessness within American horror texts become vehicles for addressing and signifying American fears …
Function Of The Enterobactin Operon Of A. Actinomycetemcomitans In The Presence Of Catecholmines And Iron., Taylor Johnson
Function Of The Enterobactin Operon Of A. Actinomycetemcomitans In The Presence Of Catecholmines And Iron., Taylor Johnson
Electronic Theses and Dissertations
Background: Aggregatibacter actinomycetemcomitans (Aa) possesses a two-component system, QseBC, which is key in biofilm formation/virulence and is activated in the presence of iron-catecholamine complexes. Aa does not synthesize enterobactin, a catechol-based siderophore, yet possesses the machinery for recognition and uptake. We hypothesize that Aa is able to acquire iron by catecholamine mediation through the enterobactin receptor/transporter. Methods: By insertional mutation, we attempted to delete the enterobactin permease from the genome using suicide vector pJT1. A growth curve of truncated mutant ΔfepA was also conducted to observe growth in the presence of iron and catecholamines. Statistical significance was determined by ANOVA …
Inhibition Of Chemotherapeutic-Induced Apoptosis In Esophageal Squamous Cancer Cells By The Keystone Periodontal Pathogen, Porphyromonas Gingivalis., Atul Kumar Agrawal
Inhibition Of Chemotherapeutic-Induced Apoptosis In Esophageal Squamous Cancer Cells By The Keystone Periodontal Pathogen, Porphyromonas Gingivalis., Atul Kumar Agrawal
Electronic Theses and Dissertations
Recent evidence has shown that P. gingivalis, a Gram-negative, anaerobic oral bacterium, is negatively associated with the presence and outcome of esophageal squamous cell carcinoma (ESCC). While potential underlying mechanisms are yet to be established, P. gingivalis infection is known to inhibit apoptosis in gingival epithelial cells. Therefore, we hypothesized that P. gingivalis may also inhibit of the induction of apoptosis in human ESCC cells exposed to the commonly employed anti-ESCC chemotherapeutic agent, cisplatin. The capacity of P. gingivalis, at variant multiplicities of infection, to suppress cisplatin-induced necrosis and apoptosis in EC9706 ESCC cells was established by lactate …
His Scent Of Sandalwood., Lujain Almulla
His Scent Of Sandalwood., Lujain Almulla
Electronic Theses and Dissertations
This creative thesis is a collection of fictional stories, connected by a common geographical and cultural thread: Kuwait. The stories unravel across a span of four thousand years. The poetic-prose style of the opening vignette is a nod to the earliest form of writing that makes up the bulk of Kuwait’s literature: poetry. The abstractedness of the two opening pieces reflects the lack of a deep-rooted national identity, and a brevity in Kuwait’s historical record. The remainder of the thesis explores the evolution of this national identity, as well as the infiltration of Western culture into modern Kuwait, and its …
Combating Malignant Melanoma With The Multifaceted Soy-Dervied Peptide Lunasin., Christopher Paul Shidal
Combating Malignant Melanoma With The Multifaceted Soy-Dervied Peptide Lunasin., Christopher Paul Shidal
Electronic Theses and Dissertations
Lunasin is a 44 amino acid peptide that has been shown to have cancer chemopreventative and chemotherapeutic properties. This study investigated the potential utility of Lunasin as a chemotherapeutic in melanomas. Studies showed that Lunasin had little activity against established melanoma cell lines using adherent culture methods; however, Lunasin’s in vitro activity was significantly higher in non-adherent colony-forming assays and oncosphere formation. These results led to the investigation of whether or not Lunasin has selective effects on cancer initiating cells (CIC) that are known to be present in melanomas. It was revealed that Lunasin selectively inhibited the proliferation of high-ALDH …
Colorectal Cancer Fit Screening In The Hope Vi Population Of Jefferson County, Kentucky., Jeffrey D. Stone
Colorectal Cancer Fit Screening In The Hope Vi Population Of Jefferson County, Kentucky., Jeffrey D. Stone
Electronic Theses and Dissertations
Using pre-post survey data collected from 209 randomly selected African American people from the population of former residents of Clarksdale and Sheppard Square public housing areas, this study explores the relationship between individual characteristics and colorectal cancer screening behavior, measured by the uptake of the Fecal Immunochemical Test (FIT) and by prior colorectal screening, while controlling for neighborhood factors and geographic proximity to healthcare facilities. This particular public housing population is of interest because of their relocation from the downtown area, where healthcare facilities are within walking distances, to other public housing units either in large apartment complexes or scattered …
Homogeneous Ligand-Centered Hydrogen Evolution And Hydrogen Oxidation : Exploiting Redox Non-Innocence To Drive Catalysis., Andrew Z. Haddad
Homogeneous Ligand-Centered Hydrogen Evolution And Hydrogen Oxidation : Exploiting Redox Non-Innocence To Drive Catalysis., Andrew Z. Haddad
Electronic Theses and Dissertations
Hydrogen is a promising carbon-free fuel / energy carrier and is an essential building block for many industrial and agricultural processes. Rising energy demands have ignited interest in the development of carbon-free and carbon neutral energy sources. In this context, hydrogen is an attractive candidate—being energy-dense, carbon-free—and easily accessible through a two-electron reduction of water. Accordingly, many electrochemical homogeneous catalyst systems have been studied, with a focus on understanding the mechanism of hydrogen evolution proceeding through metal-hydride intermediates. However, there has been a renaissance in hydrogen evolution reaction (HER) catalyst design, with many groups implicating ligand redox non-innocence as a …
Identifying The Signaling Mechanisms Of Egfr-Mediated Apoptosis., Nicole Marion Jackson
Identifying The Signaling Mechanisms Of Egfr-Mediated Apoptosis., Nicole Marion Jackson
Electronic Theses and Dissertations
The Epidermal Growth Factor Receptor (EGFR) is a 170-kilodalton transmembrane protein that belongs to the ErbB family of receptor tyrosine kinases. Upon ligand-mediated activation, the EGFR is responsible for cell growth, proliferation, and tissue homeostasis; however, the EGFR is overexpressed in many human malignancies, including MDA-MB-468 cells, a metastatic breast epithelial cell line. Studies within this cell line, and other cell lines characterized with high EGFR levels, have shown that EGF stimulation results in the induction of apoptosis. However, the mechanisms and signaling effectors implicated in this process have yet to be elucidated. The overarching research goal of this dissertation …
Untangling The Role Of Postsecondary Education In Economic Success., Erin Smith Banjanovic
Untangling The Role Of Postsecondary Education In Economic Success., Erin Smith Banjanovic
Electronic Theses and Dissertations
This dissertation explored the relationship between postsecondary education and economic success through a person-centered lens. A sample of 365,315 employed individuals between the ages of 25 and 35 from the American Community Survey (ACS) were used in combination with data from three occupational databases (O*NET, the Occupational Outlook Handbook, the NORC occupational dataset) to examine this topic. The various sources of data were merged together by occupation to permit examination of occupational characteristics and creation of two measures of education and occupation match: 1) match in education level attained and required, and 2) match in field of study and field …
I. In The Time Of The Others : A Novel ; Ii. Out Of East Pakistan : Postcolonial Colony Bangladesh As A Case Study Of Postcolonial State And Postcolonial Nation-State From East Pakistan To Independence Through The Liberation War Of 1971 : A Critical Analysis., Nadeem Zaman
Electronic Theses and Dissertations
This dissertation is a combined creative and critical project consisting a novel and a theoretical component. The novel entitled In the Time of the Others is a fictional account set during the true event of the Bangladesh Liberation War of 1971. Using the war as a backdrop, the novel tells the story of one man trying to manage his family, marriage, and financial situation by returning to an inheritance he never claimed. The journey brings him from his home in southern East Pakistan (present-day Bangladesh) to the capital city Dhaka, to the home of his maternal uncle and aunt under …
Transversal Approaches And Ecological Artwork., Madison Deanna Sevilla
Transversal Approaches And Ecological Artwork., Madison Deanna Sevilla
Electronic Theses and Dissertations
This work explores systematic ecology as it relates to sculpture and language. This project exists in two parts: a written thesis and a thesis exhibition. Although both works explore ecological systems, Unseen: Visualizing Ecological Systems investigates visualizations and concepts of the ecological, whereas this thesis continues the exploration into the ramifications of disruptions in systems. Ecological systems such as the environmental, social/mental, economic, and political define the foundations of our known world and encapsulate all regions of society. No single system can function independently of the rest and all systems contain some aspect of human-system involvement. By using the work …
Development Of Recyclable Gold Nanoparticles For Routine Benchtop Catalysis In Organic Transformations., Shengzong Liang
Development Of Recyclable Gold Nanoparticles For Routine Benchtop Catalysis In Organic Transformations., Shengzong Liang
Electronic Theses and Dissertations
Homogeneous gold catalysis is a popular research area due to its high efficiency. Various gold catalysts have been utilized in organic synthesis and their reaction mechanisms are also well understood. However, most gold catalysis suffers from high catalyst loading or catalyst decay problems. In addition, homogeneous gold catalysts are not recyclable. These disadvantages have limited their application in large-scale synthesis and also caused a serious waste of this precious metal. A solution for these problems is to use a recyclable heterogeneous gold catalyst. So in this study, with the aim of making gold chemistry greener we successfully used heterogeneous gold …
Role Of Mir-29b-1 And Mir-29a In Endocrine-Resistant Breast Cancer., Penn Muluhngwi
Role Of Mir-29b-1 And Mir-29a In Endocrine-Resistant Breast Cancer., Penn Muluhngwi
Electronic Theses and Dissertations
Therapies targeting estrogen receptor α (ERα) including selective estrogen receptor modulators (SERMs), e.g., tamoxifen (TAM); selective estrogen receptor downregulators (SERDs), e.g., fulvestrant (ICI 182,780); and aromatase inhibitors (AI), e.g., letrozole, are successfully used in treating breast cancer patients whose initial tumor expresses ERα. Unfortunately, the effectiveness of endocrine therapies is limited as ~ 40% of breast cancer patients will eventually acquire resistance to them. The role of miRNAs in the progression of endocrine-resistant breast cancer is of keen interest in developing biomarkers and therapies to counter metastatic disease. This dissertation begins with a review on miRNAs implicated …
A Tool To Evaluate Sustainability Of Pavement Maintenance Projects., Yibo Zhang
A Tool To Evaluate Sustainability Of Pavement Maintenance Projects., Yibo Zhang
Electronic Theses and Dissertations
Pavement maintenance activities are widely regarded to be critical elements during pavement life cycle, different maintenance techniques have been used to restore or extend the service lives of pavements. However, the existing maintenance practices on pavement system have problems that impair the economic benefits, disturb the natural environment, and somewhat ignore the needs from stakeholders. To minimize these negative impacts, sustainability is an ideal way because it addresses the problems under Triple Bottom Line (TBL, refers to economy, environment, and society). Sustainability analysis within transportation or pavement industry has been studied in different countries, but the concept of sustainable pavement …
The Lose-Lose Situation : Identity Prioritization And Gendered Communication In Co-Recreational Intramural Basketball., Megan Robinson
The Lose-Lose Situation : Identity Prioritization And Gendered Communication In Co-Recreational Intramural Basketball., Megan Robinson
Electronic Theses and Dissertations
Co-recreational sports deserve to be studied due to their relationship between the environment, identity prioritization, and gendered communication for individuals. In spite of the environment’s importance in collegiate student development, few have asked the questions of: how do co-recreational intramural basketball players manage their multiple identities and statuses when playing with or against members of the same or opposite sex; and how do players of both sexes use gendered communication strategies to negotiate predominantly masculine leisure environments, like intramural basketball leagues? Using in-depth interviews from co-recreational intramural basketball players at the University of Louisville triangulated with observations of co-recreational intramural …
Urban Governance Reconsidered : Assessing The Roles Of Public-, Private-, And Third Sector Leaders In Governing The Modern City., Benjamin Colby Leamon
Urban Governance Reconsidered : Assessing The Roles Of Public-, Private-, And Third Sector Leaders In Governing The Modern City., Benjamin Colby Leamon
Electronic Theses and Dissertations
As central cities redefine themselves after decades of commercial abandonment, “urban renaissance” movements, white flight, and the gentrification of their central urban neighborhoods, are cities still governed by the political-business coalitions conceptualized by urban regime theorists, or have new players emerged? Further, as cities continue to evolve within the post-Fordist landscape, do extant theories of urban governance, themselves built upon decades-old observations, continue to provide adequate models for urban governance as it actually exists in cities today? This dissertation is a quantitative and qualitative examination of contemporary urban governance in the United States, and the roles of CDCs and anchor …
Expression Of Zeb Factors In Oral Squamous Cell Carcinoma., Saira Ahmed
Expression Of Zeb Factors In Oral Squamous Cell Carcinoma., Saira Ahmed
Electronic Theses and Dissertations
Objectives: The ZEB family of transcription factors (ZEB1 and ZEB2) have been demonstrated to play a role in metastatic progression of several cancers, and may also influence the initial transformation and generation of cancer stem cells. However, the expression pattern of ZEB proteins in the development of oral squamous cell carcinoma has not been investigated. The purpose of this study was to define changes in expression and subcellular localization of the ZEB family in both precancerous lesions and different grades of OSCC. Materials and Methods: Seventy-nine tongue biopsies were subjected to immunohistochemistry and immunofluorescence to determine the expression and subcellular …
Don't Go Unless You Mean It : A Novel With Critical Afterword : Heteronormative Masculine Performance In Contemporary Fictions Of The Rural American South., Nathan N. Gower
Electronic Theses and Dissertations
This dissertation consists of a full-length novel for an adult audience as well as a substantial critical afterword to elucidate and complicate germane thematic concerns of the creative artifact. The novel, leaning on the rich traditions and many genre conventions of fictions of the American south, tells the story of an unlikely underground coal miner in Blue Banks, a fictional southern town set in the caverns and rolling hills of the western Kentucky coal fields. The narrative follows its fish-out-of-water protagonist, Cody Culver, a fledgling academic who thought he had escaped his fate as a third-generation coal miner when he …
Student Self-Assessment Of Operative Dentistry Experiences : A Time Dependent Exercise In Best Practice Outcomes., Celine Joyce Cornelius Timothius
Student Self-Assessment Of Operative Dentistry Experiences : A Time Dependent Exercise In Best Practice Outcomes., Celine Joyce Cornelius Timothius
Electronic Theses and Dissertations
Purpose: The purpose of this project was to evaluate student self-assessment of operative dentistry experiences. Methods: First, a retrospective analysis of student self-assessment and faculty assessment grade sheets were evaluated for mean differences and correlations across time. Both preclinical (D2: n=120) and clinical (D3: n=120; D4: n=120) grades sheets were evaluated. Secondly, twenty-five (n=25) students from each of the D1, D2, D3 and D4 classes were asked to evaluate dentoform work. Twenty-five (n=25) operative calibrated faculty graded the same two dentoforms. Results: D2 student’s self-assessment scores were significantly higher than the faculty assessment scores (t-test; p0.05) and there was a …
The Interaction Of Homoserine Lactones And Paraoxonase 2 Modulates Cell Death Signaling And Cell Proliferation., Aaron Mackallan Neely
The Interaction Of Homoserine Lactones And Paraoxonase 2 Modulates Cell Death Signaling And Cell Proliferation., Aaron Mackallan Neely
Electronic Theses and Dissertations
Pseudomonas aeruginosa produces N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule that functions to facilitate bacteria-bacteria communication. C12 has also been reported to affect many aspects of human host cell physiology, including evoking cell death in various types of cells. However, the signaling pathway(s) leading to C12-triggerred cell death remains unclear. To clarify cell death signaling induced by C12, we examined mouse embryonic fibroblasts (MEFs) deficient in one or more caspases. Our data indicate that, unlike most apoptotic inducers, C12 evokes a novel form of apoptosis in cells, probably through the direct induction of mitochondrial membrane permeabilization. Importantly, C12 induces apoptosis …