Digital Commons Network^™

An Investigation Of Relationship Correlates And Predictors Of Cultural Adjustment Among Missionaries., Sarah Warren

Electronic Theses and Dissertations

While research on the cultural adjustment of expatriates has existed for decades, information related to the cultural adjustment of missionaries is considerably lacking (Kimber, 2012). Information on missionary cultural adjustment often has been extrapolated from the greater expatriate population, in spite of differences existing between missionaries and other expatriates (Navara & James, 2002; 2005). This study examined the extent to which missionary relationships (with God, individuals from one’s host culture, individuals from one’s home culture, and other missionaries) correlate with and predict cultural adjustment among missionaries. Participants were recruited from the Church of the Nazarene’s Global Mission Department to complete …

Moving Mountains : A Study Examining Long-Term Impacts Of Mountaintop Removal Coal Mining On Mortality In The Appalachian Region Using Geographic Information Sciences Techniques., James Howard Kent Pugh

Electronic Theses and Dissertations

Over the last hundred years, the Appalachian region has been dominated by the coal industry. It has also been and currently is one of the unhealthiest regions in the United States. Recent scholarship has examined the relationship between coal mining and health and mortality rates in the Appalachian region. The first study incorporates air quality and pollution data to examine if coal mining counties have higher levels of pollution and if this pollution contributes to mortality disadvantage. In the second study, I construct a population-based coal-exposure measure to better evaluate the relationship between coal mining and health I find that …

Sample Size Calculations And Normalization Methods For Rna-Seq Data., Xiaohong Li

Electronic Theses and Dissertations

High-throughput RNA sequencing (RNA-seq) has become the preferred choice for transcriptomics and gene expression studies. With the rapid growth of RNA-seq applications, sample size calculation methods for RNA-seq experiment design and data normalization methods for DEG analysis are important issues to be explored and discussed. The underlying theme of this dissertation is to develop novel sample size calculation methods in RNA-seq experiment design using test statistics. I have also proposed two novel normalization methods for analysis of RNA-seq data. In chapter one, I present the test statistical methods including Wald’s test, log-transformed Wald’s test and likelihood ratio test statistics for …

A Novel Approach To Assess Minimally Invasive Surgical Device Failure Utilizing Adverse Event Outcome Severity And Design Complexity., Marie K. Riggs

Electronic Theses and Dissertations

Medical device failure and misuse have the potential to cause serious injury and death. Given the intricate nature of the instruments utilized specifically in minimally invasive surgery (MIS), users and manufacturers of surgical devices share a responsibility in preventing user error and device failure. A novel approach was presented for the evaluation of minimally invasive device failures, which involved assessing the severity of adverse event outcomes associated with the failures modes and investigating aspects of the devices’ design that may contribute to failure. The goals of this research were to 1) characterize the design attributes, failure modes, and adverse events …

Age-Related Host Factors Regulate Lung Cancer Progression., John Caleb Greenwell

Electronic Theses and Dissertations

Cancer is largely a disease of the elderly. In the United States alone, 87% of all cancers in 2017 will be diagnosed in individuals aged 50 years or older. Among them, lung cancer is the deadliest, accounting for 1 in 4 cancer deaths. The 5-year survival rate is below 20%, a number which has not changed substantially over the past several decades. This underscores a desperate need for new strategies in prevention, early detection and treatment of this deadly disease. While tobacco use is unquestionably the number one risk factor for the development of lung cancer, the majority of diagnoses …

James Franklin Bell : Hard War In The Philippines., Daniel Michael

Electronic Theses and Dissertations

This thesis surveys the military history of the Philippine-American War of 1899-1902. In particular, this thesis looks at that war through the lens of hard war as a way of war. It begins with an introduction to hard war as a concept and a historiography of the Philippine-American War and continues with an overview of the events leading up to the war. The first two chapters deal with the wider role of the U.S. Army during the war, while the third chapter examines the role of James Franklin Bell, and American officer, and his command of the Third Separate Brigade …

Southern Veils : The Sisters Of Loretto In Early National Kentucky., Hannah O'Daniel

Electronic Theses and Dissertations

This thesis analyzes the experiences of Roman Catholic women who joined the Sisters of Loretto, a community of women religious in rural Washington and Nelson Counties, Kentucky, between the 1790s and 1826. It argues that the Sisters of Loretto used faith to interpret and respond to unfolding events in the early nation. The women sought to combat moral slippage and restore providential favor in the face of local Catholic institutional instability, global Protestant evangelical movements, war and economic crisis, and a tuberculosis outbreak. The Lorettines faced financial, social, and cultural pressures—including an economic depression, a culture that celebrated family formation …

Culturally Relevant Teachers : A Critical Beacon In The Educational Standards Movement., Angela Pleasant

Electronic Theses and Dissertations

The purpose of this study was to describe culturally relevant teachers’ beliefs and teaching practices as they implement the Reading CCSS. It was hypothesized that by exploring the beliefs and practices of teachers who practice a culturally relevant pedagogy, this research could provide evidence of the specific and identifiable practices that demonstrated high expectations, culturally competency, and critical consciousness. This research could provide evidence of effective strategies, which could be used to impact the literacy achievement of students of color while the teacher implements the Reading Common Core State Standards or any standards movement that follows. A qualitative case study …

Role Of Human Arylamine N-Acetyltransferase 1 In Tumorigenesis And Cancer Biology., Marcus William Stepp

Electronic Theses and Dissertations

Human arylamine N-acetyltransferase 1 (NAT1) is a well-known phase II metabolic enzyme that has been associated with carcinogenesis. Its role in the biotransformation of aromatic and heterocyclic amine carcinogens has been investigated for many years, but more recent investigations focus on a possible endogenous role of human NAT1 in cancer initiation and progression. To further explore and understand possible endogenous roles for NAT1, we conducted in vitro enzymatic reactions, in vivo studies using homozygous high (rapid) or low (slow) NAT2 activity congenic F344.WKY rats, and genetically modified human breast cancer cell lines. Human NAT1 and rodent NAT2 hydrolyzed acetyl-coenzyme …

Self-Management As A Mediator Of The Relationship Between Social Support And Health Outcomes Of African American Adults With Type 2 Diabetes., Tariq N. Al-Dwaikat

Electronic Theses and Dissertations

Type 2 diabetes (T2D) is often associated with serious complications. African American adults have higher rates of diabetes-related complications than other ethnicities. Diabetes self-management reduces the risk of developing biological and psychological symptoms. Social support promotes positive behavior change and self-management that leads to improved biobehavioral and psychosocial outcomes. Few studies explored the relationship between social support dimensions and self-management behaviors, diabetes biomarkers, and psychosocial outcomes of African American adults with T2D. The purpose of this dissertation was to examine the relationships of various dimensions of social support with self-management behaviors and diabetes biomarkers and psychosocial outcomes of African American …

Testing And Modeling Of The Thixotropic Behavior Of Cementitious Materials., Bashir Hasanzadeh

Electronic Theses and Dissertations

During construction, concrete goes under various operations. It is normally transported to the job site, be placed and consolidated in the formwork, etc. The easiness and quality of these operations are very much related to the intrinsic rheological properties of concrete. Therefore, a good understanding of rheological behavior of concrete under various conditions are needed. Thixotropy is an important part of rheology. The thixotropic behaviors of concrete can be good representatives of its flow behaviors on the job site. For example, the breakdown aspect of thixotropy can help to explain how its flow behavior can impact concrete pumping and its …

Heterogenization Of Complexes With Redox Active Ligands For Hydrogen Evolution Reaction., Wuyu Zhang

Electronic Theses and Dissertations

Hydrogen fuel is a promising future energy carrier with many applications. Thermodynamically, 1.23 V is needed for the water electrolysis, which is a clean method to generate hydrogen gas. In practice excess potential is required, which is called overpotential, due to kinetic barriers. Catalysts to reduce the overpotential for the hydrogen evolution reaction (HER) include many homogeneous catalysts and heterogeneous catalysts. Heterogenization of homogeneous catalysts on electrode surfaces is an ideal way to study a catalyst by combining homogeneous and heterogeneous study together. In this dissertation, several characterization techniques have been employed, include cyclic voltammetry, linear sweep voltammetry, electrochemical impedance …

Emotion Socialization And Families Of Children With And Without Adhd., Danielle M. Walerius

Electronic Theses and Dissertations

Emotional competence (EC) represents several distinct emotional skills found to be strongly associated with children’s socioemotional outcomes. EC is thought to develop through a process known as emotion socialization (ES), whereby children’s emotions and emotion-based behaviors are socialized through interactions with parents and/or other primary figures. The present study examined ES across families of children with and without ADHD in order to clarify the role ES plays in the development of EC in typically developing (TD) children versus children more prone to EC impairments due to intrapersonal characteristics (e.g., inattention, disinhibition, etc.). Forty-eight children 5 to 8-years-old (23 with ADHD, …

Farmscapes : Picturing Land Transformation In Nineteenth-Century America., Eileen L Yanoviak

Electronic Theses and Dissertations

This dissertation examines American farmstead imagery of the nineteenth-century and how those images reflect the environmental history of the North. In this study, images of farms illustrate, through the landscape, the transition from subsistence farming to agribusiness that fundamentally changed American life and the land over the century. By comparing the actual ecological and economic conditions of the farm and farmer to the images depicted by artists, it is possible to see both representations of change and the persistence of the agrarian myth in spite of dramatically different realities. This study focuses on the process of change in the American …

Modeling Effective Work Groups And Teams : An Assessment Of The Inclusion Of Social Value Orientation., Gary Daniel Jones

Electronic Theses and Dissertations

The purpose of this study is to examine research on effective work groups in terms of measurable input characteristics and relevant collective outputs. Antecedents and consequences of group processes are explored; models of work groups and teams are examined and assessed in light of subsequent research. Additionally, social value orientation – a behavioral trait known to predictably influence interpersonal outcomes – is introduced as a concept that is also relevant to group work. A revised model that includes social value orientation as a predictive factor for group productivity is presented and tested. This empirical study is a correlative, quantitative investigation …

Targeting The Major Regulator Of Mitosis., J. Mason Hoffman

Electronic Theses and Dissertations

Mitosis-inhibiting chemotherapeutics (e.g. taxanes) are frequently used to treat multiple cancer types. Recently, there has been much concern about the limited success of these drugs due to resistance and a lack of molecular targets. Thus, there is high demand for new drugs with diverse cellular targets. Targeting the regulators of mitosis is a promising approach. The anaphase promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that controls cell cycle progression at multiple points. The interaction of ANAPC2 and ANAPC11, catalytic core subunits, is necessary for APC/C function. An in silico approach was used to identify compounds predicted to prevent assembly …

Metabolic Regulation Of Myocardial Adaptation To Exercise., Andrew Alan Gibb

Electronic Theses and Dissertations

While the benefits of exercise affect several organs, a significant adaptive response occurs within the heart. Exercise promotes cardiac growth, increases angiogenesis, and enhances cardiac function and these adaptations are associated with a cardioprotective phenotype. Additionally, extensive evidence shows that exercise dynamically regulates myocardial metabolism. This can be attributed to both changes in hormonal stimulation, increases in bioenergetic demand, and the bioavailability of circulating substrates. However, it is unclear whether these changes in metabolism contribute to physiologic cardiac growth. We reason that exercise-induced changes in metabolism are required to balance the catabolic and anabolic reactions needed for growth. Specifically, we …

Young Adult Literature And Empathy In Appalachian Adolescents, Kelsey R. Kiser

Electronic Theses and Dissertations

Based on recent research concluding that fiction can increase empathy, this project examines how multicultural young adult literature may encourage empathy in Appalachian adolescents. Empathy encourages prosocial behaviors, but evidence suggests that young adults’ ability to empathize has declined in recent decades. In addition, Appalachia in particular is still a relatively homogenous region as it is majority white, protestant Christian, and heteronormative. Because of this, young adults in Appalachia may encounter few diverse perspectives in real life; multicultural young adult literature can provide diverse perspectives with which teenagers can empathize in a region where they might not have similar opportunities …

The Relationship Of School-Community Partnerships With Act Benchmark Scores In Rural Tennessee Schools, Kari Eubanks

Electronic Theses and Dissertations

The purpose of this quantitative study was to determine if a relationship existed between the quality of school-community partnerships and the average score of each ACT subtest for rural Tennessee high school students. Specifically, the researcher examined the following school-community partnerships: business partnerships, university partnerships, service learning partnerships, school-linked service integration, and faith-based partnerships (Sanders, 2006). Administrators from 62 rural Tennessee high schools rated the partnerships present in their schools using the Improving Community Partnership Quality rating scale developed by Sanders (2006). Each of these ratings was compared to the participating school’s mean score for each ACT benchmark to determine …

Language Proficiency Attainment And Mobility Among Ell Students, Elizabeth Ayers Neill

Electronic Theses and Dissertations

The impact student mobility has on academic achievement has been researched in the United States since the early 20^th century (Goebel, 1978). Mobility for students is a risk factor often compounded by poverty, ELL students are at a higher risk of lower achievement. Educators face challenges in tracking records, monitoring, remediating, gap closing, and assisting students in transition periods. The data collected in this quantitative study was analyzed to determine the impact mobility has on English language learners and their attainment of a second language. This quantitative study examined the relationship between non-mobile and highly mobile ELL students in …

Discharge Readiness For Families With A Premature Infant Living In Appalachia, Kathy Zimmerman

Electronic Theses and Dissertations

With increased advances in technology, the overall survival rates in the Neonatal Intensive Care Unit (NICU) for premature infants at lower gestational ages, has also increased. Although premature infants survive at lower gestational ages, they are often discharged to home with unresolved medical issues. While the birth of a new baby for parents is a joyous occasion, they often have difficulty coping and transitioning into a parental role. Premature infants also have ongoing complications such as difficulty with feeding, developmental delays in growth, and long-term eye and respiratory complications. As a result of chronic health sequelae, premature infants require extensive …

Social-Ecological Factors Affecting Patient Shield Use Among Radiologic And Computed Tomography Technologists, Megan Housenick-Lee

Electronic Theses and Dissertations

Medical radiation is estimated to contribute to over 200,000 deaths annually. Recent increases in the use of radiation-producing medical imaging examinations have led to increasing cumulative radiation dose to the general public. Multiple measures have been taken to address this alarming trend, including physician education, technologist education on dose reduction, and equipment-facilitated dose reduction techniques. Shield use can reduce the primary beam by up to 95%. Medical imaging technologists are the primary individuals responsible for applying shielding during an examination. Currently, literature shows that technologists are not shielding individuals as often as they should.

After pilot testing, medical imaging technologists …

Projecting Culture Through Literary Exportation: How Imitation In Scandinavian Crime Fiction Reveals Regional Mores, Bradley Hartsell

Electronic Theses and Dissertations

This thesis reexamines the beginnings of Swedish hardboiled crime literature, in part tracking its lineage to American culture and unpacking Swedish identity. Following the introduction, the second chapter asserts how this genre began as a form of escapism, specifically in Maj Sjöwall and Per Wahlöö’s Roseanna. The third chapter compares predecessor Raymond Chandler’s The Big Sleep with Roseanna, and how Sweden’s greater gender tolerance significantly outshining America’s is reflected in literature. The fourth chapter examines how Henning Mankell’s novels fail to fully accept Sweden’s complicity in neo-Nazism as an active component of Swedish identity. The final chapter reveals …

The Algz/R Two-Component System Is Responsible For Attenuation Of Virulence In Pseudomonas Aeruginosa, Danielle A. Williams

Electronic Theses and Dissertations

Pseudomonas aeruginosa is an important opportunistic pathogen. Many P. aeruginosa virulence factors are regulated by the AlgZ/R two component system. AlgZ is the sensor histidine kinase which phosphorylates AlgR, the response regulator. AlgR activates transcription of different gene targets based upon its phosphorylation state. The genes that encode AlgZ and AlgR are transcribed in an operon. While regulation of algR expression has been well studied, regulation of algZ expression has not. Using a pilW mutant in concert with algZTF-lacZ transcriptional fusion, we conducted a transposon mutagenesis to identify algZ regulators. We identified an unknown autoregulatory loop. The type …

Study Of 2,5-Diaminoimidazolone, A Mutagenic Product Of Oxidation Of Guanine In Dna, Hannah Catherine J. Pollard

Electronic Theses and Dissertations

2,5-diaminoimidazolone (Iz) is an important product of a 4-electron oxidation of guanine. The present research focuses on the mechanisms of formation of Iz via pathways initiated by guanine oxidation by one-electron oxidants (OEOs) generated by X-ray radiolysis in aqueous solutions. The kinetics of formation and yields of Iz in reactions of native highly polymerized DNA with different OEOs have been compared using an HPLC-based quantitative analysis of low-molecular products generated from the reaction of DNA-bound Iz with primary amines. Mechanisms of Iz formation in DNA have been investigated including oxygen and superoxide dependence as well as the hypothesis that 8-oxo-G, …

Exogenous Ubiquitin: Role In Myocardial Inflammation And Remodeling Post- Ischemia/Reperfusion Injury, Stephanie Scofield

Electronic Theses and Dissertations

Sympathetic stimulation occurs in the heart after injuries such as ischemia/reperfusion (I/R) and myocardial infarction and affects myocardial remodeling. Prolonged sympathetic stimulation can result in myocardial dysfunction through its effects on cardiac myocyte apoptosis and myocardial fibrosis. Ubiquitin (UB) is well known for its role of tagging old or damaged proteins for degradation via the UB-proteosome pathway. The role of exogenous UB however, is not fully understood. Previously, our lab showed that β-adrenergic receptor (β-AR) stimulation increased levels of extracellular UB in the conditioned media of adult rat ventricular myocytes and that UB inhibits β-AR-stimulated apoptosis. This study investigates the …

Spatially Explicit Model Of Areas Between Suitable Black Bear Habitat In East Texas And Black Bear Populations In Louisiana, Arkansas, And Oklahoma, Caitlin M. Glymph, Christopher Comer, Daniel Scognamillo, Daniel Unger, Yanli Zhang

Electronic Theses and Dissertations

Although black bears (Ursus americanus, Ursus americanus luteolus) were once found throughout the south-central United States, unregulated harvest and habitat loss resulted in severe range retractions and by the beginning of the twentieth century populations in Oklahoma, Louisiana, Texas and Arkansas were nearing extirpation. In response to these losses, translocation programs were initiated in Arkansas (1958-1968 & 2000-2006) and Louisiana (1964-1967 & 2001-2009). These programs successfully restored bears to portions of Louisiana and Arkansas, and, as populations in Arkansas began dispersing, to Oklahoma. In contrast, east Texas remains unoccupied despite the existence of suitable habitat in the region.

To facilitate …

Estimating Wildlife Biodiversity Of Pine Plantation Edges Of Contrasting Rotational Stages: A Case Study, Joshua Perry Harris

Electronic Theses and Dissertations

ESTIMATING WILDLIFE BIODIVERSITY OF PINE PLANTATION EDGES OF CONTRASTING ROTATIONAL STAGES: A CASE STUDY

By: Joshua Harris, Dr. Daniel Scognamillo, Dr. Gary Kronrad, and Dr. Jeremy Stovall

Abstract

Wildlife biodiversity was estimated amongst three loblolly pine (Pinus taeda) intra-plantation edge types of contrasting rotational phases in a two-year case study. Three structurally varied rotational phases that occur throughout plantation rotations combine to make three different edges: A= pre-thinned - post-thinned, B= pre-thinned - pre-clearcut, and C= post-thinned - pre-clearcut. For two summer seasons (May-August 2015-2016), invertebrates, birds, medium mammals, and small mammals were sampled in each edge type. …

Computational Prediction Of Conductivities Of Disk-Shaped Particulate Composites, Jian Qiu

Electronic Theses and Dissertations

The effective conductivities are determined for randomly oriented disk-shaped particles using an efficient computational algorithm based on the finite element method. The pairwise intersection criteria of disks are developed using a set of vector operations. An element partition scheme has been implemented to connect the elements on different disks across the lines of intersection. The computed conductivity is expressed as a function of the density and the size of the circular disks or elliptical plates. It is further expressed in a power-law form with the key parameters determined from curve fittings. The particle number and the trial number of simulations …

The Sequence Stratigraphic Context Of Mixed Basin Margin Evaporites In The Harrisburg Member Of The Permian Kaibab Formation, Northern Arizona And Southern Utah, Cole Hendrickson

Electronic Theses and Dissertations

The Kaibab Formation is a mixed carbonate system including evaporites and siliciclastics deposited on a westward dipping epeiric carbonate ramp during the middle Permian in northern Arizona, southern Utah, and eastern Nevada. It consists of the Fossil Mountain Member deposited in open-marine conditions and the overlying Harrisburg Member deposited in restricted conditions. The Harrisburg Member includes facies and depositional environments ranging from open-marine shallow-subtidal wackestone - packstone, restricted subtidal dolomitic mudstone, dolomitic sandstone, peritidal oolitic grainstone as well as gypsum and red siltstones deposited in a sabkha environment.

Fourteen stratigraphic sections were measured across northern Arizona and southern Utah to …