Digital Commons Network^™

Modeling Disorder In Proteins Yields Insights Into The Evolution Of Stability And Function, Jonathan Huihui

Electronic Theses and Dissertations

The central dogma of molecular biology dictates that a DNA sequence codes for an RNA sequence, which in turn codes for a sequence of amino acids that comprises a protein. Proteins are responsible with performing myriad functions within living organisms and most proteins require a folded structure in order to perform their function. The protein's structure is the direct link from sequence to function. This is known as the sequence - structure - function paradigm. However, this does not mean that the unfolded state is unimportant. In order to properly model the stability of the folded state, one needs to …

Intellectual Property Rights In The Seed Industry: Barriers To Sustainable Agriculture, Elena A. Filatova

Electronic Theses and Dissertations

The dynamics of the dominant industrial agriculture system restrict the seed industry’s innovative landscape, leading to significant negative consequences including an exacerbation of environmental risks which threaten global food security. This thesis explores how exclusionary intellectual property rights (IPRs) in the context of the seed industry constrict innovation, evolutionary pathways, and opportunities for the implementation of sustainable agriculture methods. To overcome these barriers, the application of an open source framework to seed innovation, specifically through the platform of the Open Source Seed Initiative, is evaluated as a tool for enhancing innovative capacities in seed development while broadening the accessibility and …

Level Of Acceptance (Loa) For Scan-To-Bim Creation, William Fulton Ikerd Ii

Electronic Theses and Dissertations

This dissertation presents two contributions to the use of Reality Capture and Scan-to-BIM for facility management (FM). The first manuscript proposes a novel construct for accurately defining scope on Scan-to-BIM projects. Combining the concepts of tolerance, accuracy, and density of point cloud measurements, it will aid laser scan usage in new construction as-built validation, help renovation of existing buildings that lack as-built documentation, and support facility managers who lack accurate plans and digital twins of their buildings by helping determine and communicate the appropriate requirement for Scan-to-BIM. In view of making this process more efficient and cost effective, this article …

Observation Of New Particle Formation In The Northern Hemisphere At Altitude From 4 To 20 Km, Mohamed Saad

Electronic Theses and Dissertations

New particle formation (NPF) is investigated using measurements of aerosol size distributions and meteorological variables made in two continents, including USA and Europe. Despite the considerably different aerosol particle abundances among the sites, a common relationship was found between the characteristics of NPF events and the air mass convective and/or advective transport. CO and O3 act as tracers of tropospheric and stratospheric air, respectively, their statistical relationship can be used to quantify air mass characteristics and origins. The mixing ratio values of CO increased within the upper troposphere layer before/during NPF events, which may serve as an indicator of occurring …

The Hotelling Valuation Principle: Does User Cost And Reserve Differentials Improve Validity?, Brian K. Hicks

Electronic Theses and Dissertations

The Hotelling Valuation Principal (HVP) implies that the value per unit of an in-ground exhaustible natural resource is equal to the current price less the cost of production. The assumptions required for this principle include a certain and homogenous reserve stock, unconstrained extraction, and constant costs. Extensive research has empirically investigated the HVP. This paper expands the HVP framework and relaxes the theory’s assumptions to account for reserve differentials. The results show that the original net price model is more closely aligned with developed reserve value, than total reserve value. In addition, this paper develops two- and three-factor net price …

Understanding Libyan Teachers’ Intentions And Classroom Practices In Teaching English As A Foreign Language, Khaled El Mezughi

Electronic Theses and Dissertations

International demand for learning English has increased dramatically during the last three decades. The ability to speak English has become an essential tool of global communication in many sectors, including international commerce, science, technology, and entertainment. Little research has been conducted to examine the teaching methods and instructional practices being used in Libyan EFL classrooms and their impact on the students' use of English in authentic situations. Due to the importance of improving both the teaching and learning of English as a Foreign Language (EFL) in Libya, the aim of this study is to understand EFL Libyan educators’ classroom instructional …

Understanding Patterns And Functional Impacts Of An Invasive Tree And Its Biological Control In A Riparian System, Annie L. Henry

Electronic Theses and Dissertations

Invasive species have become an inextricable part of the landscape, particularly in riparian plant communities, and removal is often a key component of restoration programs. Biological control (biocontrol) is a method of removal that is often both efficient and effective. However, the impact of biocontrol on target species and indirect effects from invasive species removal can be hard to predict. While monitoring the impact of invasive species removal usually involves some species-based assessment such as changes in diversity, historically dominant species or native species, these strategies do not typically provide insight into the mechanisms underlying plant community response to removal. …

Distributed Control, Optimization, And State Estimation For Renewable Power System, Qiao Li

Electronic Theses and Dissertations

The traditional power systems are usually centralized systems, in which the control, operation and monitoring are performed by the centralized control center, e.g., SCADA. However, with the development of renewable energy, power systems are getting more and more distributed. So, it becomes necessary to establish the distributed power system operation methods for these power systems. In this research, the distributed techniques for the renewable power systems are proposed based on the consensus protocol technique from graph theory. These techniques cover the three important problems in power systems, i.e., economic dispatch, state estimation, and optimal power flow. First, the Distributed Economic …

Stories Of Return: A Collection Of Repatriation Narratives, Lydia Degn-Sutton

Electronic Theses and Dissertations

This thesis examines the museological phenomena of repatriation beyond NAGPRA and the incorporation of Indigenous curatorial methods into museum collections practices. The project explores repatriation and collections caretaking practices at ten settler institutions through narratives of experience collected from museum staff. The findings of this research suggest that repatriation beyond NAGPRA and the Indigenization of collections care are situated processes that should be understood contextually and historically. This thesis argues that, in some cases, repatriation beyond NAGPRA and the integration of Indigenous perspectives, practices, and protocols into museum collections stewardship demonstrates a willingness by institutions to go beyond the minimum …

Understanding The Latinx Student Experience In A First-Year, Non-Remedial, Terminal College Math Course: A Convergent Mixed Methods Study, Ross Morgan

Electronic Theses and Dissertations

Working with Latinx students, a semester long study was conducted in the Spring of 2021 to better understand student’s perception of Culturally Responsive Teaching Practices (CRTP) at Mountain State University (MSU). The course sections selected are a part of a larger first year, non-remedial, terminal mathematics courses designed to provide students with smaller teacher to student ratios as well as opportunities to earn credit towards graduation. Instructors in two of the sections received special training around CRTP, while instructors in the other two sections did not receive this training. Findings demonstrate that simple adjustments to instructional practices had a statistically …

Design Of Lower Legs Of Mithra, A High-Performance Backdrivable Humanoid Robot, Drake Taylor

Electronic Theses and Dissertations

This thesis presents the design of the knee and ankle of Mithra, a new humanoid robot that aims to be an energy-efficient and highly agile machine. Mithra makes use of new optimization metrics for legged robots to develop a system capable of mimicking human movement. A series of low-impedance, high-torque actuator systems were developed with the goal of creating lightweight, powerful, and robust motion. The structure of Mithra's legs mimics the human structure in leg segment length and weight proportions. Detailed design and analysis were conducted in order to allow Mithra to be a robust and maintainable system. Mithra will …

The Duality Of Reality: Perception Creation Using Symbolic Management, Christopher J. Thomas

Electronic Theses and Dissertations

People have historically used different types of symbols to signal an ideology, to create a sense of prestige, or to gain legitimacy. Examples of these types of symbols can be seen in displays ranging from marketing ads to presidential election materials. While these types of symbols tend to be socially constructed, and universally identifiable, the consequences of their use are less uniform in nature. This study explores the gap that currently exists between a symbol’s inherent value and the expected consequences of its use. My theoretical prediction includes two principles: The use of symbolic management to create symbolic environments and …

Change Request Prediction And Effort Estimation In An Evolving Software System, Lamees Abdullah Alhazzaa

Electronic Theses and Dissertations

Prediction of software defects has been the focus of many researchers in empirical software engineering and software maintenance because of its significance in providing quality estimates from the project management perspective for an evolving legacy system. Software Reliability Growth Models (SRGM) have been used to predict future defects in a software release. Modern software engineering databases contain Change Requests (CR), which include both defects and other maintenance requests. Our goal is to use defect prediction methods to help predict CRs in an evolving legacy system.

Limited research has been done in defect prediction using curve-fitting methods evolving software systems, with …

The Institutional Design Of Arms Control: To What Extent Does Institutional Design Increase The Longevity Of Arms Control Agreements?, Jessica Budlong

Electronic Theses and Dissertations

The technical institutional design of arms control agreements remains a rather unexplored area of arms control. But the increasing uncertainty of future arms control efficacy requires a re-examination of the agreements’ institutional design to determine which components contribute positively to their longevity. This research examines the role of dispute settlement bodies as specific outside consultative bodies, verification regimes, membership as at least one nuclear-armed state party to the agreement, and technology transfer mechanisms in arms control agreements. It found that membership and a lack of technology transfer mechanisms are necessary to positively impact the longevity of an arms control agreement, …

Design, Manufacture, And Test Of A Hybrid Aerial-Ground Robotic Platform, William Garrett Willmon

Electronic Theses and Dissertations

A hybrid aerial-ground robotic platform allows for enhanced functionality combining most of the operational profiles of an aerial and ground vehicle with applications to intelligence, surveillance, reconnaissance (ISR), infrastructure inspection, emergency response, photography, etc. Motivated by this challenge, we designed, developed, and tested a prototype hybrid aerial-ground robotic vehicle capable of guidance, navigation, and control in the air and on the ground. The thesis focus is on the system design. As such, at first, we designed and analyzed the mechanical component to ensure durability. We then designed the electrical component to reduce overall weight and maximize battery life. We developed …

An Educator Out Of Water: A Phenomenological Study Into Identity-As-Educator For Student Affairs Professionals, David Mccoy

Electronic Theses and Dissertations

The work of student affairs professionals has been happening since the inception of western higher education. The profession has shifted a great deal since that time, with an emphasis now on student affairs professionals as ‘educators’ alongside their faculty counterparts. Regardless of change, research has consistently demonstrated the impact student affairs can have on the experiences of students and colleges as a whole. Given the emergence of identity-as-educator, for these professionals to best continue their work, it is imperative to understand how they understand and make sense of this professional identity. This research was a phenomenological study to understand how …

Mechanisms Of Sensory Adaptation In The Primate Visual System, Boris Isaac Peñaloza Rojas

Electronic Theses and Dissertations

Under ecological conditions, the luminance impinging on the retina varies within a dynamic range of 220 dB. Stimulus contrast can also vary drastically within a scene, and eye movements leave little time for sampling luminance. In addition, the amount of information reaching our visual system far exceeds the brain’s information processing capacity. Given the limited dynamic range of its neurons and its limited capacity in processing visual information in real-time, the brain deploys both structural and functional solutions that work in tandem to adapt to the surroundings. In this work, employing visual psychophysics and computational neuroscience, we study the mechanisms …

Nucleic Acids Promote Oligomerization Of Immunoglobulin G, Alexa Gomez

Electronic Theses and Dissertations

Nucleic acids have been found to prevent aggregation as chaperones, as well as act as co-factors and promote aggregation of amyloidogenic proteins leading to various diseases. Immunoglobulin G, IgG, are prone to aggregate as therapeutic proteins, and light chains of IgG can form amyloid fibrils, causing a disease known as light chain amyloidosis. Here we discuss the effect nucleic acids have on full-length immunoglobulin G aggregation. Our results show G-quadruplex DNA, and bulk DNA lead to oligomerization of full-length IgG, and induce increases in secondary structure. Tryptophan fluorescence indicates structural changes are occurring in the presence of DNA. Additionally, IgG …

Righteous Remixes, Sacred Mashups: Rethinking Authority, Authenticity, And Originality In The Study Of Religion, Seth M. Walker

Electronic Theses and Dissertations

This dissertation sets out to place emergent theories of “remix” in conversation with scholarship exploring changes in the definitions and practices associated with the word “religion.” Through particular case studies, the dissertation analyzes the ways that certain contemporary creators, writers, and influencers have emerged as constructors of contemporary Buddhism. Specifically building upon the critiques of religion put forth by Jonathan Z. Smith, Russell T. McCutcheon, Brent Nongbri, Jane Iwamura, and others, I am concerned with how individuals who are not part of the religious studies scholarly community participate in the processes of constructing religion, and in this case, in constructing …

A Biophysical Investigation Of Hiv-1 Envelope Cytoplasmic-Tail Mediated Retention In The Gag Lattice, Nicholas Scott Groves

Electronic Theses and Dissertations

The infectivity of Human Immunodeficiency Virus is critically dependent on successful incorporation of the trimeric viral envelope glycoprotein, Envelope (Env), into Gag lattice assembly sites on the host-cell plasma membrane during virus biogenesis. The mechanistic nature of interaction between Gag, the structural protein, and Env, the viral spike, are dependent on the Gag matrix (MA) and Env cytoplasmic tail (CT) domains. Env laterally diffuses on the host cell plasma membrane until encountering a budding Gag lattice, where it is retained until particle scission and release. The mechanism of Env entry and retention in the lattice remains elusive and enigmatic. Here …

The Design, Development, And Determination Of A Virtual Reality Classroom, Victoria Alexxis Reddington

Electronic Theses and Dissertations

The COVID-19 pandemic has radically changed the way students learn and engage with their peers and instructors. Likewise, instructors have had to quickly transform their course materials to suit the online classroom format. Results from a survey of students and instructors at the University of Denver revealed that perceived levels of learning and collaboration were lessened with the transition to online learning. Moreover, the sense of presence in an educational atmosphere with other individuals was reported to be significantly stronger in a real physical classroom, as compared to an online classroom. This thesis therefore seeks to provide a new, alternative …

Correlating With Local Variation In Collagen Level And Mechanical Properties Of The Heart Tissues, Talayeh Tavangar

Electronic Theses and Dissertations

The determination of the myocardium's tissue properties is essential in constructing finite element (FE) models of the heart. To obtain accurate results, especially for functionally modeling the heart, we must determine the tissue properties in-vivo. The calculation of the heart tissue properties remains a challenging area as it is categorized as a heterogeneous, anisotropic, nonlinear soft tissue that undergoes large deformation. In this work, we tried to introduce and evaluated a finite element method to determine the mechanical properties of the cardiac tissue. The introduced method combined a finite element modeling with the experimentally obtained images from the left and …

Math Achievement Of Low-Socioeconomic Status Students: A Comparative Study Of Public-School Settings, Alexander Ohene Ansah

Electronic Theses and Dissertations

In recent years, falling standards in the American public-school system have elicited public concern and criticism, leading to several public-school reforms. One such reform is the charter-school movement. Charter schools provide a public option for parents in search of an alternative to traditional public schools. At the same time, the achievement gap continues to widen, with students of low socioeconomic status on the losing end. Since the beginning of the charter school movement, research has focused on comparisons in achievement between students in charters and traditional public schools. Results have been mixed.

Focusing on low-SES student populations in Colorado, this …

Corporate Ventures: Relational Microfoundations Of Innovation Performance, Burak Malkoc

Electronic Theses and Dissertations

Large, established companies invest in innovation to sustain and improve their competitiveness. In addition to in-house R&D departments, they acquire startup companies and operate them under a separate organizational structure. Corporate ventures’ success depends on many factors, such as available resources, compensation schemes, and acquisition strategies, which have been explored in the extant literature. This study explores the antecedents of corporate venture innovation performance through the lens of dynamic capabilities and social capital theories. Existing research on dynamic capabilities has explored its microfoundations of managerial cognition and top management initiatives. However, the development of dynamic capabilities requires actors’ level interactions …

Deep Learning Methods For Fingerprint-Based Indoor And Outdoor Positioning, Fahad Alhomayani

Electronic Theses and Dissertations

Outdoor positioning systems based on the Global Navigation Satellite System have several shortcomings that have deemed their use for indoor positioning impractical. Location fingerprinting, which utilizes machine learning, has emerged as a viable method and solution for indoor positioning due to its simple concept and accurate performance. In the past, shallow learning algorithms were traditionally used in location fingerprinting. Recently, the research community started utilizing deep learning methods for fingerprinting after witnessing the great success and superiority these methods have over traditional/shallow machine learning algorithms. The contribution of this dissertation is fourfold:

First, a Convolutional Neural Network (CNN)-based method for …

Recycling Of Fiber Polymer Matrix Composites In Cementitious Materials, Edward Patton Clark

Electronic Theses and Dissertations

Recycling options for fiber polymer matrix composite waste materials are limited because they typically cannot be reused, reprocessed for down-cycling, and are generally environmentally unfriendly. The utility industry, specifically electrical distribution, has been increasingly using hybrid carbon, glass fiber, and epoxy resin composite rods for high-voltage (HV) conductor transmission lines. The high-voltage conductor core (HVCC) used in the transmission line can have an optimal in-service-life of roughly several decades, in which the material is then retired to a waste landfill. Currently, there is limited research and recycling methodology for these hybrid composite rods. In this research, powder carbon fiber, glass …

Optimal Sizing And Operation Of A Pumped Thermal Energy Storage System, Matthew Perez

Electronic Theses and Dissertations

Current trends in the modern grid are leading to the integration of energy storage technologies (ESSs), such as pumped thermal energy storage to help incorporate more variable renewable energy sources into the grid. This paper analyzes the operation of a pumped thermal energy storage (PTES) system under the grid services of energy arbitrage, regulation services, spinning and non-spinning reserve, resource adequacy, and a combination of them all. Each revenue stream is setup into an optimization problem and solved to find which revenue generating technique would generate the most revenue. The combined revenue stream was found to produce the most revenue …

The Martyr’S Desire: Levinas, Girard, And Infinite Responsibility, Joshua Alan Lawrence

Electronic Theses and Dissertations

Perhaps the whole of human history could be summed up with one word: economy. The law of the home and the home of all law. Without fail, this situation results in a structured devotion that must decide what to do with desire. And the economic decision often follows a violent trajectory, most commonly described as sacrifice. Today, states will make efforts to conceal this underlying logic, but the insidious configurations of ‘real politik’ usually surface with a frightening intensity.

My project considers these problematic vestiges through Emmanuel Levinas’s reconfiguration of subjectivity. To address these bio-historical realities, my work highlights the …

Thermal Performance Of Algan/Gan Based Power Switching Devices For Transformerless Inverters, Mahesh B. Manandhar

Electronic Theses and Dissertations

Wide Bandgap (WBG) semiconductors like Silicon Carbide (SiC), Gallium Nitride (GaN) and Aluminum Gallium Nitride (AlGaN) have superior material properties as compared to Silicon (Si) like higher electrical breakdown voltages and bandgap energies as well as lower leakage currents as compared to Si which make them ideal to operate at higher voltage with lower thermal losses. These properties make WBG materials ideal for power devices like Vertical Double-diffused Metal Oxide Semiconductor Field Effect Transistors (VDMOSFETs). The use of digital prototyping through computer simulation increases the speed and flexibility of the design iterations while reducing the cost and time required for …

Wind Turbine Parameter Calibration Using Deep Learning Approaches, Rebecca Mccubbin

Electronic Theses and Dissertations

The inertia and damping coefficients are critical to understanding the workings of a wind turbine, especially when it is in a transient state. However, many manufacturers do not provide this information about their turbines, requiring people to estimate these values themselves. This research seeks to design a multilayer perceptron (MLP) that can accurately predict the inertia and damping coefficients using the power data from a turbine during a transient state. To do this, a model of a wind turbine was built in Matlab, and a simulation of a three-phase fault was used to collect realistic fault data to input into …