Digital Commons Network^™

Validation Of A Novel Heritable Rodent Model Of Drug Abuse Vulnerability In Psychosis And Investigation Of Therapeutic Targets, Loren D. Peeters

Electronic Theses and Dissertations

Schizophrenia is a severe neuropsychiatric disorder of largely unknown etiology that is often accompanied by high rates of cigarette smoking, reduced quit success, and high relapse rates. Dysregulated dopamine signaling and aberrant synaptic plasticity in the mesocorticolimbic pathway are implicated in the pathophysiology of schizophrenia and conferred substance abuse disorder and relapse vulnerability. Genetic factors are presumed to play a significant role in the development of schizophrenia, with a 40-50% concordance rate for monozygotic twins, although genetic markers are inconsistent. As such, epigenetic factors have instead been implicated. Specifically, there is strong evidence to suggest DNA methylation at several candidate …

Groundswell, Ursula Gullow

Electronic Theses and Dissertations

The artist discusses the artwork of her Master of Fine Arts exhibition, Groundswell, held at Tipton Gallery in Johnson City, March 11 – 22, 2024. The exhibition includes wall pieces, sculpture, plaster, and ceramic objects that explore the traditional parameters of painting and its presentation.

Ideas discussed include the philosophy of history, and the origin of European art tropes such as odalisques, flowers, and birds. Framing devices, deconstructed paintings, fiber arts, ceramics, 18^th Century decorative art, plaster, the studio practice, Walter Benjamin, David Lowenthal, Gustave Courbet, Jean Honoré Fragonard, Titus Kaphar, Valerie Hegarty, and maximalism are also surveyed.

Design And Validation Of A Test For Teachers: Measuring Knowledge Of Trauma, Jennifer B. Bilbrey

Electronic Theses and Dissertations

Research and interest in trauma-informed pedagogy have grown substantially. Trauma-informed pedagogy includes knowledge of trauma symptoms, associated behaviors, and environmental and instructional trauma-informed strategies. Various scales measure attitudes and experiences with trauma-informed practices; however, the literature suggests a lack of validated tests measuring teachers' knowledge of trauma. Reliable and valid tests measuring knowledge are critical when determining the professional development needs of both pre-service and in-service teachers. This multi-phase study aimed to fulfill this need by creating the Teachers’ Knowledge of Trauma (TKOT) test. With the guidance of literature and qualitative data from eight early childhood professional peers, a 50-item …

The Beast In The Beauty: An Analysis Of Cultural Gender Biases And Stereotypes In The Classic Fairy Tale “Beauty And The Beast” And Implications In Modern Retellings, Lauren Lefler

Electronic Theses and Dissertations

This thesis looks at the fairy tale Beauty and the Beast to examine the way that this tale has been used throughout history to address the concerns of young women, as well as reinforce the culturally accepted gender roles of the time of their publication. The first chapter defines the fairy tale genre and features some of the most common criticism on the genre, it will then define and offer critical perspectives on the monster bridegroom motif which Beauty and the Beast is a part of. The second chapter will look at the first two publications of the text, the …

Physiological Adaptations Following A Strength Endurance Training Block Performed With Accentuated Eccentric Loading Or Traditional Resistance Training, Alex Long

Electronic Theses and Dissertations

Physiological adaptations were investigated following a strength-endurance (S-E) block prescribed with accentuated eccentric loading (AEL) or traditional resistance training (TRAD). Recreationally trained participants (n = 11 males, 6 females, age = 23.2 ± 4.2 yrs, body mass (BM) = 81.3 ± 22.2 kg, height = 172.1 ± 10 cm) completed a four-week block of concurrent resistance, sprint, and change of direction training. Participants were assigned one of two training conditions, AEL (n = 9) or TRAD (n = 8). Training was identical, except AEL performed 110% eccentric overloading every 1^st, 3^rd, 5^th, 7^{th …}

Depositional Facies And Petrophysical Characterization Of The Leonardian Carbonate (Lower Clear Fork), Tex-Mex, S.E. Field, Central Basin Platform, West Texas, Seyram Nyamasekpor

Electronic Theses and Dissertations

The Lower Clear Fork from Tex-Mex, S.E. Field on the Central Basin Platform is a typical complex reservoir that displays high heterogeneity in lithological and petrophysical properties. The unit represents a producing reservoir succession of Leonardian platform carbonates deposited in shallow marine water during the Early Permian. The sediment of the Lower Clear Fork is composed of a mixed succession of dolomite interbedded with anhydrite, minor clay minerals, and siliciclastics. The high heterolithic nature of the reservoir makes efficient recovery of hydrocarbons difficult. This situation requires an understanding of the variability in depositional facies in terms of mineralogy, depositional textures …

Exploring Peer Perspectives On Autistic Students: A Vignette Study, Justin Linville

Electronic Theses and Dissertations

A 2x2 design was undertaken to determine the effects of vignette character gender and autism disclosure status on social distance scores, reading comprehension performance, and false memory induction. The introduction focuses on the theoretical threads taken from the autism, false memory, and gender literatures and how they combine to create the underpinning of the current design. A second more controlled study was compelled by initial false impressions of the deleterious effects of fast completion times. This second study resulted in lengthened completion times and improved vignette comprehension. Two-way MANOVAs with gender and autism disclosure serving as independent variables on the …

A Phenomenological Study On The Lived Experiences Of Black Male Faculty At Predominantly White Institutions (Pwis) In Texas And Louisiana, Christopher Allen Frazier

Electronic Theses and Dissertations

The purpose of this transcendental phenomenological study was to gain more clarity and insight into a distinctive phenomenon of the lived experiences of five African American male professionals in predominantly White institutions in Texas while seeking tenure and promotion. Using interviews throughout the duration of the study allowed the phenomenological inquiry to gain better insight from a personal lens while hoping to find the true essence of the phenomenon. All participants in this inquiry were African American male professionals who served in educational roles and had at least 3 years’ experience serving in a predominantly White institution in Texas. This …

As The Night Is Lit: The Nocturnal Urban Landscapes Of Childe Hassam., Diana M. Wilder

Electronic Theses and Dissertations

The scientific investigations into light that began with the Enlightenment garnered added information useful for artists. To depict the changes in light due to weather, time of day, and season more accurately, artists took the information reaped from studies of the refraction of light gained from Isaac Newton’s color theories. The new technological advances of gaslight and electric arc lighting also changed the way that light was represented on canvas. Artists were now able to paint in their ateliers due to modern lighting that would light up the rooms like the day. Some artists decided to explore the night and …

Preventing The Violent (Re)Victimization Of Sexual Minority Populations: The Role Of Social Support Networks., Bryan Charles Moore

Electronic Theses and Dissertations

Every year, interpersonal violence affects an important segment of the world population, having deleterious effects on the victims, their families, and societies. Recent scholarship indicates that sexual and gender minority population groups are overrepresented among those who experience or have experienced verbal, psychological, physical, and/or sexual violence. Using an integrative approach, the current study links the past and the present to identify the contextual factors that may increase or decrease the sexual minorities’ risk of violent victimization during adulthood. This dissertation uses as a theoretical framework Bronfenbrenner’s (1977, 1979, 1994) social ecological model of human development as well as its …

Mattie Castlebury: East Texas Oil Boom Legend, Olivia L. Moore

Electronic Theses and Dissertations

The discovery of the East Texas Oil Field in 1930 was a pivotal moment, reshaping the region’s economic and social dynamics. Mattie Castlebury emerged as a standout figure among the fervor of the oil boom, leaving an indelible mark on East Texas’ cultural identity. Castlebury’s story showcases resilience and resourcefulness as she navigated the challenges of the oil boom era. She established Mattie’s Ballroom, creating a bustling leisure and entertainment hub.Through her entrepreneurial strategies, Castlebury’s impact on the community is evident, shaping East Texas’ cultural fabric.

The “Women of the Boom” exhibition at the Kilgore College East Texas Oil Museum …

The Making Of The Russian At Christmas, Armando Rey Silvas Jr.

Electronic Theses and Dissertations

This thesis will explain the process of making my feature film, The Russian at Christmas, which I wrote, directed, and edited myself. I will discuss my influences for the film, and how those influences led to my own visual and writing style. By walking through the stages of pre-production, production, and post- production, I will discuss the film from conception to completion. My time in the SFA film program – including working on four other summer features – prepared me to direct my own feature film. Completing this feature film was a daunting task that has no comparison to …

The Experiences Of Questbridge Scholars At Elite Universities, Karla J. Leybold

Electronic Theses and Dissertations

In this dissertation, I examined the experiences of QuestBridge Scholars attending three different elite universities that enroll more students from the top income quintile than from the lowest three income quintiles combined. The universities attended by participants in this study are among the few that are both need-blind and that fully meet students’ demonstrated financial need through grant and scholarship aid. Additionally, these universities have acceptance rates of no more than 10%. The QuestBridge organization’s mission is to match high-achieving, low-income students with elite institutions.

Data from participants were collected through an audio and video recorded interview using a semi-structured …

Macrophage Polarization And Colorectal Cancer Immune Checkpoint Protein Expression., Anne Macleod

Electronic Theses and Dissertations

The majority of patients with colorectal cancer do not respond to treatment with immunotherapy. Immunotherapy requires the expression of cell surface immune checkpoint proteins (e.g. PDL1) to exert its effect. Most (>85%) of colorectal cancers do not express these proteins and this contributes in part to the poor prognosis and survival in patients with advanced disease. The patients in which immunotherapy is a potential treatment option, are a genetic subtype known as mismatch repair deficient, and have demonstrated an excellent response to anti-PD-1/PDL1 immunotherapy. A key feature of mismatch repair deficient (MMRd) cancers is their immune cell rich tumor …

Development And Evaluation Of A Modeling Platform For Evaluating Immunotherapeutic Efficacy In The Tumor Microenvironment., Dylan Andrew Goodin

Electronic Theses and Dissertations

The tumor microenvironment (TME) represents the complex outcome of numerous tumor, stromal, and immune interactions, and whose composition can significantly affect treatment response. Particularly, immunotherapeutic efficacy is subject to multiple tumor-specific TME interactions that may be difficult to evaluate/predict clinically. Mathematical modelling has been formulated to evaluate specific aspects of the TME, including vasculature, ECM deposition, and immune-tumor interactions. However, the computational challenge of simulating multiple TME interactions has led to sacrificing varying degrees of model generalizability and clinical relevance. This work describes increased computational performance of a 3D continuum model that simulates tumor tissue, ECM, and vasculature using a …

The Affable Raphael: Milton's Surrogate Instructor In Paradise Lost., Beau Kilpatrick

Electronic Theses and Dissertations

John Milton’s Paradise Lost (1667) is a beautifully written epic that continues to be a stalwart text in the English literary canon, with unlimited potential for interpretation. In this dissertation I propose that Paradise Lost can be read as a pedagogical lesson for Milton’s “fit audience,” where the author implements his views on education in the context of heaven, hell, and Paradise. In the poem, Milton presents three pedagogical methodologies: first, the wrong way to knowledge is presented through Satan’s manipulations of the fallen angels and Eve; second, the divine way to knowledge is illustrated via Michael’s prophecy to Adam …

Dementia Of The Alzheimer’S Type In Adults With Down Syndrome: Knowledge Among Graduate Students In Physical Therapy, Occupational Therapy, And Speech-Language Pathology., Abigail Regan Donaway

Electronic Theses and Dissertations

This non-experimental study utilized a convenience sample (N = 322) to investigate graduate students in physical therapy (PT), occupational therapy (OT), and speech-language pathology’ s (SLP) knowledge of the connection between Down syndrome and dementia of the Alzheimer's type (DAT). Ninety-two-point-five percent of participants were female, and 79.80% were white. All participants completed a survey comprised of items relating to information about general knowledge (i.e. facts) of the association between DS and DAT, the signs/symptoms that occur in each stage of dementia of the Alzheimer’s type for people with Down syndrome, and familiarity regarding the diagnosis and care. Descriptive and …

Faculty And "Teams": Academic Literacies In The Post-Lockdown, Digital University., Morgan Suzanne Blair

Electronic Theses and Dissertations

The increased presence of disruptive digital technologies in academia has been a subject of multidisciplinary scholarly conversation and public speculation over the past few decades. Many literacy studies scholars have contributed to this discourse, examining topics like multimodal literacies and perceptions of agency among students. These scholars have noted with skepticism that such technologies may mask operations of power, surveillance, and control which serve the demands of an increasingly “corporate” or “neoliberal” university. Building upon this scholarship, my study contends that the evolving literacy environment of the digital university requires a closer examination of corporate-sponsored narratives and literacy practices implicating …

Smart Manufacturing Of Cement: From Lab-Scale Simulation And Testing To Industry-Scale Deployment., Juan David Tabares Tamayo

Electronic Theses and Dissertations

Cement kilns are controlled by experienced process operators who follow experience-based industry guidelines using data collected and fundamental knowledge. The manufacturing process, which is equipped with sensors and equipment, transfers data/information to the operators to aid standardized decision-making operations. In contrast, companies have used such data to develop and implement digital solutions for predictive control systems; in effect, FLSmidth and Rockwell Automation. However, despite the availability of automated control systems and investigation in automation for process monitoring and optimization, opportunities to radically optimize cement manufacturing are still abundant and in need of implementation. Therefore, this research developed simulation models and …

Porphyromonas Gingivalis Inactivates Anti-Viral Immunity At The Oral And Respiratory Epithelium., Carlos J. Rodriguez Hernandez

Electronic Theses and Dissertations

The host microbiome plays an important role in fine-tuning host immune responses in a manner that ultimately impacts outcomes in viral infection. Symbiotic relationships between commensal bacteria and host epithelial and immune cells prime interferon (IFN) signaling, modulating the nature and intensity of the immune response to viral infections at mucosal barrier surfaces. In this doctoral thesis, I explore how dysbiotic shifts in the oral microbial communities modulate antiviral responses at the oral and oro-respiratory mucosal barriers. I identified that in response to a viral challenge, gingival epithelial cells (GECs) preferentially induced type III IFNs (IFN-λ), a newly described family …

Using A Planetarium To Support Pre-Service Elementary Teachers' Development Of Ngss-Aligned Science Teaching., Breanna Graven

Electronic Theses and Dissertations

This dissertation is a case study of five elementary pre-service teachers within a science methods course who attended a planetarium-enriched experience. The experience was designed and taught by an instructor with both experience and education in astronomy and with K-12 students. The focus of the planetarium experience was to teach the science content these PSTs will have to teach to their future elementary students and teach how to teach science in an NGSS-aligned way, by incorporating the Science and Engineering Practices and Crosscutting Concepts. This is a qualitative case study that relied on interviews, open-response surveys, and video prompt responses …

Class Of 1884: Black Education In Louisville And The Inaugural Graduating Class Of Central Colored High School., Jordan Tierre Jackson-Collins

Electronic Theses and Dissertations

This thesis offers both a historical analysis of the emergence of the black public school system in Louisville, Kentucky and a probe into the academic posture of 19^th century black education in the state. It addresses how the early black school in Kentucky worked to shape students’ self-image and worldview by focusing on Louisville’s Central Colored High School, the first public high school for blacks in Kentucky, and more closely, its 1884 yearbook––a collection of student-essays in which each of the seven inaugural graduates wrote lengthy reports concerning their individual outlook on education, American society, and the Negro’s responsibilities …

“I’M Going To Have To Be Far More Prepared": A Critical Discourse Analysis Of Teacher Candidate Discussion And Projected Teaching Of Literature., Taylor Rose-Dougherty

Electronic Theses and Dissertations

This qualitative dissertation study contributes to conversations around the practical knowledge gap–professional behaviors or practices which are underdeveloped in available research–between critically oriented literacy teacher preparation programs and praxis in early career classrooms. Critical literacy, or engaging with major texts, discourses, and ways of communicating in a culture or context, attempts to locate and disrupt power imbalances and encourage justice-oriented activism. While teacher candidates (TCs) often practice critical literacy in their training programs, they often struggle to facilitate critical literacy instruction in their own classrooms. Using Thematic Analysis (TA) for data reduction and Critical Discourse Analysis (CDA) for data analysis, …

Attention Guided Data Augmentation For Improving The Classification Performance Of Vision Transformers., Nada Baili

Electronic Theses and Dissertations

For over a decade, Deep Neural Networks (DNNs) have been rapidly progressing and achieving great success, forming a robust foundation of state of the art machine learning algorithms that impacted various domains. The advances in data acquisition and processing have undeniably played a major role in these breakthroughs. Data is a crucial component in building successful DNNs, as it enables machine learning models to optimize complex architectures, necessary to perform certain difficult tasks. However, acquiring large-scale data sets is not enough to learn robust models with generalizable features. Instead, an ideal training set should be diverse enough and contain enough …

Are The Good Times Really Over For Good? American Political Nostalgia's Relationship With Rurality, Authoritarianism, And Victimhood., Chancellor R. Peterson

Electronic Theses and Dissertations

There are many discussions about why rural and urban Americans exhibit different attitudes about politics, partisan loyalties, and ideologies. Some of these differences can be explained by psychological processes and traits. People act differently and influence (or are influenced by) political processes differently based on their perceptions of and emotions regarding the past, present, and future states of the world. The same is true with rural and urban Americans. This research will investigate the effects of one potent emotion on political attitudes: nostalgia. Prior research has indicated that political nostalgia can be harnessed as a strong political tool. This thesis …

Preserving Archaeology In The Digital Age: Evaluating Strategies For Effective Curation And Database Management., Cenetria Leshun Crockett

Electronic Theses and Dissertations

The “curation crisis” is a dark cloud that consistently looms over the archaeological discipline, affecting the ways we plan, execute, and curate research projects. It is especially prominent within curation facilities and institutions that have the duty to preserve archaeological collections. The development of digital curation presents an avenue through which curators and collection managers can combat the crisis. Digital curation grants collection managers the ability to manage and ensure archaeological collection accessibility. Digital collection databases, particularly, have grown to become a significant component of collection management as it permits collections to be easily preserved, managed, saved, and accessible at …

Teacher Identity Matters: The Influence Of Identity On Student/Teacher Relationships And Special Education Student Performance., Jamil Anderson

Electronic Theses and Dissertations

I have had the opportunity of many years of experience in public education as a teacher who provides services for students who in Special Education. I have classes where there is a small group setting for content instruction, as well as the role of a “co-teacher” alongside general educators. From my work, I find that there are differences of expectations of success and rigor in the inclusive setting from the general education teacher, often resulting in deficits in their academic achievement when compared to their peers who do not receive services. As I developed my topic for this study, it …

Educator Perceptions Of Blended Teacher Professional Development: A Case Study Of A Vertically Aligned Virtual Professional Learning Community., Aslean White

Electronic Theses and Dissertations

This case study describes the design and enactment of a job-embedded, blended learning professional development plan for teachers to facilitate the collaborative inquiry of a vertically aligned virtual professional learning community. The study is of relevance because it seeks to implement recommendations from recent research on online teacher professional development (Barnett, 2020; Lockee, 2020; Powell & Bodur, 2019) using a framework for support structures designed to engage learners in blended and online learning environments (Philipsen et al., 2019). This qualitative multi-case study examined individual teacher cases using a within-case analysis to create teachers’ profiles to illuminate contextual traits and elucidate …

A Case Study: The Influence Of Professional Development, Administrative Support, And Co-Planning On Teacher Perceptions Of Co-Teaching., Heidi Zimmerman

Electronic Theses and Dissertations

This dissertation presents a case study methodology investigating the influence of professional development, administrator support, and co-planning on teacher perceptions of co-teaching. My interest in co-teaching increased as a former special education teacher after implementing co-teaching strategies in my own practice. As defined by the Kentucky Administrative Regulations, Collaboration means, a teacher of exceptional children works with children with disabilities in the regular classroom to provide specially designed instruction and related services (707 KAR 1:350, Section 2). Oftentimes, Collaboration and Co-Teaching may be used interchangeably. For the purpose of this study, the term Co-Teaching will be used throughout. The goal …

A Qualitative Inquiry Into The Intersectionality Of Race, Gender, And Social Networks In Stem Education., La'ree Alexandria Shontee

Electronic Theses and Dissertations

This study explores the intersectional experiences of Black women in Science, Technology, Engineering, and Mathematics (STEM) education by focusing on the strategic utilization of social capital to navigate systemic barriers and challenges. The unique struggles faced by Black women within predominantly white and male-dominated STEM programs are addressed in this study. Drawing on a growing body of literature, this research diverges from prevailing narratives of disinterest in or departure from STEM programs and instead illuminates proactive strategies employed by Black women. Through an exploration of social capital - encompassing networks, resources, and support systems - this study offers a comprehensive …