Digital Commons Network^™

"Maybe Jesus Was Suicidal Too": A Qualitative Inquiry Into Religion And Spirituality In Suicide Attempts, Elizabeth Ryan Hall

Electronic Theses and Dissertations

Among the current trends in suicidology that hold promise for suicide prevention are a focus on new areas for empirical exploration and the employment of creative methodologies to ascertain these phenomena. One such area is religion, along with its more enigmatic counterpart, spirituality. Suicidological research has long demonstrated that people who are religiously involved tend to be more protected from suicide than those who are not, yet it has been less attentive to the conditions under which religion or spirituality fails to inhibit suicidality. In the decades since Durkheim's renowned 1897 study, the majority of the related research has taken …

Quantifying And Simulating Fine-Scale Spatial Patterns In Plant Populations, Darin Schulte

Electronic Theses and Dissertations

Plant ecology as a discipline has increasingly acknowledged the importance of fine-scale spatial patterns in developing our understanding of community/population dynamics. These spatial patterns are largely determined by direct and indirect interactions between plants and their immediate neighbors. Such interactions thus play an important role in the structure and function of plant communities. Study of these types of local interactions has greatly benefitted from simulation based approaches. one such simulation method, agent-based modeling, has increasingly been identified as a useful tool for simulating these fine-scale interactions, and for investigating theoretical descriptions of underlying processes. Similarly, statistical techniques aimed at quantifying …

Small Rho Gtpase Family Member Cdc42 And Its Role In Neuronal Survival And Apoptosis, Noelle Christine Punessen

Electronic Theses and Dissertations

Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's and Parkinson's disease are caused by a progressive and aberrant destruction of neurons in the brain and spinal cord. These disorders lack effective long term treatments, and existing options focus primarily on either delaying disease onset or alleviating symptomology. Dysregulated programmed cell death, known as apoptosis, is one of the most significant contributors to neurodegeneration, and is controlled by a number of different factors. Rho GTPases are a protein class with recognized importance in proper neuronal development and migration, and have more recently emerged as regulators of apoptosis and neuronal survival. …

The Association Between Parent-Child Relationship And Child Loneliness, Nanxi Xu

Electronic Theses and Dissertations

Relatively little research has been conducted to examine the role of parent-child relationships in understanding loneliness during middle childhood. Twelve second to fourth grade children attending several elementary schools in a large western urban district were asked to complete the Loneliness and Social Dissatisfaction Questionnaire (LSDQ, Asher, Hymel & Renshaw, 1984) and the Parent-child Relationship Questionnaire (PCRQ, Furman & Giberson, 1995). The parents of all child participants were also invited to complete the same questionnaires. A sample of eight children, four who reported highest scores and four who reported lowest scores on the LSDQ, participated in follow-up qualitative interviews which …

Identifying The Relevance Of C-Reactive Protein Conformers And The Advancement Of A Membrane Curvature Binding Assay, Carrie Leine Moon

Electronic Theses and Dissertations

Lipid membranes play a vital role in cell signaling processes. Membrane shape and lipid content affect interactions between cellular membranes and proteins. This research focuses on characterizing those interactions and their impact by using various biochemical and biophysical assays. These assays were applied to C-reactive protein (CRP), an immune system protein that interacts with lipid membranes and has at least two forms with different properties. Native, pentameric CRP (pCRP) is found in blood serum and is commonly used as a marker for inflammation. The modified form of CRP (mCRP) binds to the protein C1q, which activates the complement immune response. …

Mechanistic Insights Into The Radical S-Adenosyl L-Methionine Enzyme Mftc, Bulat Khaliullin

Electronic Theses and Dissertations

Mycofactocin is a putative peptide-derived redox cofactor in Mycobacterium family. Its putative biosynthetic pathway is encoded by the operon mftABCDEF. The initial step of this pathway is a posttranslational modification of a peptide precursor MftA, which is catalyzed by MftC enzyme. This modification only occurs in the presence of chaperone MftB. Here, we demonstrate that MftC is a radical S-adenosyl L-methionine (SAM) enzyme and we examine its catalytic mechanism. We show that the modification of MftA requires two equivalents of SAM and is implemented in two steps: (i) the decarboxylation of a C-terminal tyrosine, resulting in formation of an …

The Effects Of Microaggressions On Probationers' Psychological Well-Being, Whitney Fujii-Doe

Electronic Theses and Dissertations

Studies examining microaggressions and individuals in the correctional system are limited. Previous studies have found experiences of perceived microaggressions have a negative impact on an individuals psychological well-being (Nadal, Griffin, Wong, Hamit, and Rasmus, 2014). The current study looked at the effects of microggressions on probationers' psychological well-being. The current study aimed to examine among probationers: hypothesis 1A, the level of microaggressions is significantly negatively associated with self-esteem; 1B, self-esteem will negatively be associated with probationers' psychological well-being; 2A, the experience of microaggressions would significantly predict levels of psychological distress; and hypothesis 2B, self-esteem would be negatively predicted probationers' psychological …

Exploring Historical Coffee And Climate Relations In Southern Guatemala: An Integration Of Tree Ring Analysis And Remote Sensing Data, Diego Pons

Electronic Theses and Dissertations

This dissertation makes use of a physical geography perspective to examine the relationship between agriculture and climate in Guatemala using dendrochronology. I examined the potential of high-resolution climate proxy data from dendrochronology to help fill in the gaps of past climate information to better understand the natural and anthropogenic variability of precipitation which, in turn, can inform Guatemala’s agriculture sector. This research has demonstrated successful cross-dating and climate sensitivity of Abies guatemalensis in the Pacific slope of Guatemala. Based on this, I have produced a 124-year record of mean precipitation from June-July-August. The mean precipitation from June-July-August at this site …

Characterization Of The Atcc Α-Tc1-6 Pancreatic Alpha Cell Line To Study Glucagon Secretion, Larissa M. Ikenouye

Electronic Theses and Dissertations

The endocrine pancreas is responsible for maintaining glycemic equilibrium in the body. Given the importance of this blood-glucose homeostasis and the implication an unbalance has on Diabetes mellitus, the study of the glucose-sensing alpha and beta cells in the pancreas is a popular field for scientific researchers. In this study, we use immunofluorescence, qPCR analysis, intracellular calcium experiments, and biochemical glucagon secretion assays to determine if the commercially available tumor cell line clone, α-TC1-6 obtained from American Type Culture Collection, is an appropriate model system for glucagon secretion in pancreatic alpha cells. We confirm the production of the hormone peptide …

Black, Queer, And Blessed: Toward A Biblically Based Black, Queer Narrative Of Leadership, Arthur Leon Tredwell

Electronic Theses and Dissertations

This dissertation focuses on the evolution of traditional African-American religious leadership as it evolved during the first half of the twentieth century. It traces the two primary models of Black religious leadership that emerged from White, cis, benevolent and dominating models of patriarchy. This task is accomplished primarily through a survey of the ministries of Adam Clayton Powell Sr. and Jr. (1908-1970) and their consecutive sixty years of ministry at the Abyssinian Baptist Church, Harlem, New York. It intentionally engages the issue of homophobia, demonstrating how it operates in Black churches generationally.

Determining these historical patriarchal models of leadership to …

Looking Through A Trauma Lens: A Caregiver's Perspective Of Child Welfare Involvement, Erin Ruth Boyce

Electronic Theses and Dissertations

The majority of maltreatment perpetrated against children is at the hand of their primary caregiver, most often their mother. The reasons why caregivers maltreat their children are still being investigated. However, the caregiver's history of trauma, in particular cumulative trauma that leads to trauma symptomology is emerging as an explanation for maltreatment. Popular theory describes the coercive and oppressive nature of child welfare system policy and practices, as a source of re-traumatization for caregivers with a trauma history (Harris & Fallot, 2001). Currently, the field of child welfare practice is largely guided by the use of trauma-informed practices, which are …

Effects Of Collaborative Problem Solving Training For Parents Of Children With Challenging Behavior In A Public School Setting, Tyra B. Vickers

Electronic Theses and Dissertations

The intent of the Think:Kids Collaborative Problem Solving (CPS) Parent Group Therapy curriculum is to help parents recognize the underlying skill deficits contributing to their child's challenging behavior, identify pathways leading to the behavior, and make environmental changes to prevent problem behavior. This quasi-experimental study assessed the effects of implementing a 6-week, 12-hour Think:Kids CPS parent curriculum in a public school setting with an intervention group compared to a non-random waitlist group. Data was collected for both groups at pre-, post-and one-month follow-up on the following measures: the Parent Child Relationship Inventory (PCRI); the Parenting Stress Index, 4th edition, Short …

Interpreting American Indian Cultural Heritage: Visitor's Educational Experience At Rock Ledge Ranch Historic Site, Kara Lynn Underwood

Electronic Theses and Dissertations

The following research and analysis explore the various methods in which American Indian heritage is interpreted at Rock Ledge Ranch Historic Site in Colorado Springs, CO. Attention was given to the distinctive ways this space acts as an educational institution that displays and interprets Colorado's cultural heritage through object-centered learning and participatory education. The goal for this research was to discuss ahistorical biases that have existed in museums for centuries, while encouraging dialogue and discourse about the appropriate methods for interpreting American Indian cultural heritage. Through the presentation and examination of visitors' educational experiences using observations, questionnaires, and informal interviews …

Health-Seeking Behaviors In Rural West Ghana, Cathryn Lynn Perreira

Electronic Theses and Dissertations

This thesis is the result of an exploratory project that included a six-week period of fieldwork in the rural farming village of Humjibre in the Western Region of Ghana. It examines the health-seeking behaviors I witnessed in this village, and discusses the barriers and facilitators that control those behaviors. It is my intention to demonstrate that there are many factors that influence concepts of health that lead to health behaviors. To fully understand how an individual functions within a medical culture, all the social, cultural, political, historical, and economic factors must be considered. Extensive background research was conducted prior to …

Uncertainty, Interference, And Communication In Bereaved Parent-Child Relationships, Veronica Anne Droser

Electronic Theses and Dissertations

Research on familial loss has centered individualized experiences with grief, constructing a disconnect between family members that works to weaken interdependence and create additional coping challenges. Through a family systems lens, the current study explored family loss from a relational perspective, centering the parent-child experience as a unique and conflictual one. Drawing from the Relational Turbulence Model (RTM) and the Theory of Motivated Information Management (TMIM), this work used actor partner interdependence models (APIM) to test a dyadic and integrated model that centered relational experiences with uncertainty, interference, and information management for 29 bereaved parent-child dyads. Further, to understand more …

Improving The Practice And Culture Of Early Learning In Ohio, Diana Morello-Deserio

Electronic Theses and Dissertations

How can preschool programs situated in public schools “get better at getting better?” This dissertation suggests a framework based on the principles of Improvement Science as one-way school districts can include preschool in their continuous improvement efforts. Document Analysis, is the method used to examine a continuous improvement protocol used in Ohio school districts known as The Ohio Improvement Process (The OIP Guide was the document analyzed). Additionally, Portraiture as “lived” experiences including both early learning educators and traditional school age leaders were reflected upon. The following research questions guided the study: What are the key operational components of the …

Mammography Utilization In African American Women, April D. Kidd

Electronic Theses and Dissertations

Purpose: Breast cancer presents differently among women causing breast cancer health disparities with women of color disproportionally shouldering later-stage screening, incidence, and treatment, and greater mortality. This study assessed 10 predictors and rates of recent and long-term mammography utilization for women 43-79 years of age to better understand differences among age strata and races. This was the first study to use both the calculated Gail Risk scores (calculates absolute breast cancer risk over time intervals) from the 2010 National Health Interview Survey (NHIS) and a temporary homelessness variable in predicting mammography utilization using national-level data.

Theoretical Framework: A modified Behavioral …

Neuronal Gq Structures In Neurodegeneration, Damian S. Mcaninch

Electronic Theses and Dissertations

This study investigates protein nucleic acid interactions between various proteins and G quadruplex (GQ) forming messenger RNAs (mRNAs) in human neurological disorders. GQ structures are formed in DNA/RNA, when four guanine residues form planar tetrads stabilized by Hoogsteen base pairing, that stack forming a GQ structure stabilized by potassium ions. These GQ structures are targeted by the arginine-glycine-glycine (RGG) repeat domain containing RNA-binding domain.

Three RGG domain containing RNA-binding proteins, all of which have been implicated in neurological disorders, and their interactions with GQ forming mRNAs, were investigated in this study: fused in sarcoma (FUS), fragile X mental retardation protein …

Experiences And Perceptions Of Rural Postpartum Women With Substance Use Disorders Inclusive Of Opioids Regarding Their Care, Debra Kramlich

Electronic Theses and Dissertations

Perinatal opioid use and neonatal withdrawal continue to rise rapidly in the face of the growing epidemic of opioid addiction in the United States, with rural areas more severely impacted. Despite several decades of research and development of practice guidelines, maternal and neonatal outcomes have not improved substantially. This focused ethnography aimed to address that gap by exploring rural women’s experiences and perceptions of care to inform development of efficacious, holistic models of care to improve outcomes for these women and their children. Participant observations, oral accounts and formal interviews, and artifact review (i.e., health records, any print and electronic …

Mechanochemical Synthesis Of Fuels From Sustainable Sources Utilizing Solid Catalysts, Jacob Todd

Electronic Theses and Dissertations

Mechanochemistry requires less solvents which results in less waste generation. The question becomes can we apply mechanochemistry to current chemical reactions and reduce the generation of waste. This process can be simple or can be very extensive resulting in the generation of large amounts of waste and very little product. A significant advantage of mechanochemistry is the reduced need for solvents that would be common place for reactions. Mechanochemistry transfers energy to reagents via impacts from milling media. Energy can be transferred to the reagents no matter their state-of-matter. Much of the current studies in mechanochemistry today are done using …

The Roles Of Perceived Stress, Coping Styles, And Perceived Social Support On The Alcohol Consumption Among American College Students, Jesse Wynn

Electronic Theses and Dissertations

The intention of this study was to better understand how certain aspects in a college student's life (i.e., perceived stress, styles of coping, and social support) or how combinations of these variables may contribute to higher levels of alcohol consumption. The present study examined the relationship between perceived stress, functional coping strategies, dysfunctional coping strategies, and perceived social support using Lazarus and Folkman's model of stress, appraisal, and coping. A sample of (N = 201) University of Denver undergraduate students between the ages of 18-25 complete measures of perceived stress, coping strategies, perceived social support, and alcohol use. Results …

Ancestral Queerness: Normativity And Deviance In The Abraham And Sarah Narratives, Gil Rosenberg

Electronic Theses and Dissertations

Interpreters of the Abraham and Sarah narratives in Gen 11-21 often focus on the importance of the line of inheritance, through a particular biological child. While they also note the many irregularities in Abraham and Sarah's familial relationships and activities, there has been no sustained attention to the combination of deviance and normativity that characterizes these narratives. I argue that, due to their particular combinations of normativity and deviance, Abraham and Sarah are Queer, where Queer is a general, cross-cultural category which includes but is not limited to contemporary forms of queerness (e.g., lesbian, gay, bisexual, transgender, intersex, etc.).

Using …

Shhhuicide Stories: A Crip Critical Analysis Of Attempt Survivors' Narrations Of Suicidality, Emily Krebs

Electronic Theses and Dissertations

Estimations suggest that one person in the United States tries to take their own life every 38 seconds (Yeager & Roberts, 2015, p. 38), making suicide the 10th leading cause of death in the nation (AFSP, 2016). Despite the prevalence of this issue, communication surrounding suicidality remains scarce - as do concrete understandings of what causes the desire to die in the first place. Dominant understandings link suicidality to chemical/neurobiological issues in the brain (mental illnesses), but these claims have not yet been scientifically proven (Hjelmeland, Dieserud, Dyregrov, Knizek, & Leenaars, 2012) and, as this study suggests, biomedical aspects of …

Dense Core Vesicle Heterogeneity In Anterior Pituitary Cells, Kelly Sinak

Electronic Theses and Dissertations

Peptides, which are packaged in dense core vesicles, are an integral part of the function of the endocrine and neurological systems. The dense core vesicles function as an efficient form of peptide storage prior to regulated exocytosis. Two different dense core specific transmembrane proteins traffic different when comparted to retained prolactin cores, offering evidence of heterogeneity of vesicles within a single cell. By comparing synaptotagmin 1 and 7 distribution in male rat and lactating female lactotrophs, a distinct pattern emerges. Cells that retain prolactin cores after exocytosis correspond with those that contain synaptotagmin 1. This finding is a reversal for …

Governmentality/Animacy/Mythology: A Biopolitical And Rhetorical Mosaic Of Hiv Stigma In A Time Of Prep-Aration, Brendan Geoffrey Aaron Hughes

Electronic Theses and Dissertations

Since 1981, roughly 35 million people have died from the Acquired Immune Deficiency Syndrome (AIDS), the end stages of the Human Immunodeficiency Virus (HIV), and an estimated 39 million are living with HIV today. While various factors such as poverty, lack of education, and poor access to treatment and healthcare compound the epidemic across the world, the endemic in the industrialized west faces specific communication-based challenges to slowing the spread of HIV. Now classified as a "chronic manageable condition", an HIV diagnosis is no longer the death sentence of the early outbreak in the 1980's. A major factor in the …

Preclinical Assessment Of Immunocal® As A Preventative Treatment For Traumatic Brain Injury (Tbi) In A Mouse Model Of Closed Head Injury, Elizabeth Eugenia Ignowski

Electronic Theses and Dissertations

Over the past three decades, traumatic brain injury (TBI) has been considered a "silent epidemic" and recognized as an emergent public health problem by the Centers for Disease Control and Prevention (CDC). TBI is defined as a bump, blow, or jolt to the head that disrupts the normal function of the brain. Due to the debilitating effects and prevalence of TBI, novel preventative treatment regimens are highly desirable in at risk populations. According to the CDC groups disproportionately affected by TBI include athletes, people aged 75+, and service men and women, among others. Here, we investigated a unique whey protein …

The Effect Of Parental Population Density On Offspring Immune Function, Dana Davis

Electronic Theses and Dissertations

It is well known that an individual's environment, genetic code, and gene by environment interactions have an effect on its overall phenotype. However, there is a growing body of work that shows that parents can have an effect on their offspring's phenotype beyond the inherited genetic code. Studies have shown that parents may affect their offspring through physiological mechanisms such as egg provisioning and epigenetic effects and through behavioral mechanisms such as maternal care. In many of these cases, the parental effect is triggered by an environmental cue. Previous work has shown that density can impact immune function and cuticle …

Selfhood, Historical Consciousness, And The State In International Relations Theory, Edinson Oquendo

Electronic Theses and Dissertations

This work seeks to examine the role of the state in international relations. While international relations treat states as institutions endowed with agency, they lack any means of explaining how the state can gain agency, autonomy, and rationality.

My dissertation seeks to reorient the theoretical assumptions of international relations in two ways. I develop a theory of the of the state that seeks to explain the mechanisms by which individuals are able to form collective social institutions and to endow them with authority and agency. I examine the relationship of the individuals to collective bodies such as states that can …

Aztec Human Sacrifice As Entertainment? The Physio-Psycho-Social Rewards Of Aztec Sacrificial Celebrations, Linda Jane Hansen

Electronic Theses and Dissertations

Human sacrifice in the sixteenth-century Aztec Empire, as recorded by Spanish chroniclers, was conducted on a large scale and was usually the climactic ritual act culminating elaborate multi-day festivals. Scholars have advanced a wide range of theories explaining the underlying motivations and purposes of these abundant and regulated ritual massacres. Recent scholarship on human sacrifice in ancient Mexico has observed far more complexity, nuance, and fluidity in the nature of these rituals than earlier mono-causal explanations. Several recent examinations have concentrated their analysis on the use of sacred space, architecture, movement, and embodiment in these festivals. As an extension of …

Meta-Analyses Of The Relationship Between Depression And Nine Dimensions Of Perfectionism, Gabriel Lynn Hottinger

Electronic Theses and Dissertations

Perfectionism has been shown to be related to depression, but perfectionism is multidimensional. Some dimensions are related to positive psychological characteristics and outcomes and other dimensions are related to negative psychological characteristics and outcomes. This study reports results of nine meta-analyses performed to investigate the association between each of nine subscales of perfectionism and depression to determine which dimensions of perfectionism are most strongly associated with depression. The two subscales that were used from the Hewitt and Flett (1991b) Multidimensional Perfectionism scale were Self-Oriented Perfectionism (SOP) and Socially-Prescribed Perfectionism (SPP). The five subscales that were used from the Frost et …