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Identification Of Qtl Modifying The Activity Of The Tcb1-S Locus And Characterization And Sequencing Of Two Plutonium-Beryllium Induced Reduced Gametophyte Transmission Mutants In Maize, Merritt Bryer Burch

Electronic Theses and Dissertations

This thesis is split into two independent projects both involving the male gametophyte generation of maize. The first project looks at how pollen interacts with the female gametophyte to reduce its transmission in cross-incompatible reactions controlled by the unilateral cross-incompatibility system, teosinte crossing barrier 1. The second project explores two plutonium-beryllium induced male gametophyte mutants and attempts to uncover their genetic basis.

Identification of QTL Modifying the Activity of the Tcb1-s Locus
Teosinte crossing barrier 1 (Tcb1) is a unilateral cross-incompatibility system present in maize that provides a pre-zygotic pistil barrier to plants carrying Tcb1-s (strong allele) from pollen …

Effects Of Yogurt Fortification With Different Legumes Protein On The Physio-Chemical, Microbiological, And Rheological Properties, Prachi Pahariya

Electronic Theses and Dissertations

Nowadays, yogurt (a nutritious fermented dairy product) is getting popular around all over the world due to beneficial action provided by bacteria present in yogurt culture. Along with that, diet plans, which are high in protein and low in fat, has become appealing for growing healthy conscious population that makes a huge shift toward plantbased protein consumption. Therefore, the main objective of this research was to study the effects of yogurt fortification with extracted protein of different beans (legumes)- pinto and kidney beans on the physio-chemical (Moisture, Fat, Protein, Ash, Total Solids Content (TSC), pH, Titratable Acidity (TA), Water Holding …

Dissecting Rna Silencing Pathways In Sclerotinia Sclerotiorum, Pauline Mochama

Electronic Theses and Dissertations

RNA silencing, also known as RNA interference, is an essential mechanism in plants, animals and fungi that functions in gene regulation and defense against foreign nucleic acids. In fungi, RNA silencing has been shown to function primarily in defense against invasive nucleic acids. RNA-silencing- deficient fungi show increased susceptibility to virus infection. Plant pathogenic fungi also utilize RNA silencing to silence plant host immunity genes through the delivery of fungal small RNAs into plants. This cross-kingdom RNA silencing facilitates fungal infection of plants. Overall, these findings demonstrate the significant contributions of fungal RNA silencing pathways to fungal virulence and viral …

Statistical Algorithms And Bioinformatics Tools Development For Computational Analysis Of High-Throughput Transcriptomic Data, Adam Mcdermaid

Electronic Theses and Dissertations

Next-Generation Sequencing technologies allow for a substantial increase in the amount of data available for various biological studies. In order to effectively and efficiently analyze this data, computational approaches combining mathematics, statistics, computer science, and biology are implemented. Even with the substantial efforts devoted to development of these approaches, numerous issues and pitfalls remain. One of these issues is mapping uncertainty, in which read alignment results are biased due to the inherent difficulties associated with accurately aligning RNA-Sequencing reads. GeneQC is an alignment quality control tool that provides insight into the severity of mapping uncertainty in each annotated gene from …

Quantifying Potential Long-Term Changes In Erosion, Discharge, And Total Suspended Solids Resulting From Agricultural Land Use Change In South Dakota, Hector Manuel Menendez Iii

Electronic Theses and Dissertations

South Dakota is a mosaic of grasslands, wetlands, and cropland. A continuing shift from grassland to cropland has occurred over the past decade and is expected for the next 50 years. Rate of future conversion may vary greatly in response to regulatory, economic, and social factors. Concern has risen over environmental consequences associated with land conversion, which include but are not limited to changes in rill and sheet erosion rates from cultivated soils, stream and river discharge, and water quality. Quantifying future changes for these three externalities is important to understand the possible long-term consequences of complex grassland conversion decisions …

Replication, Virulence, And Pathogenesis Of Influenza Viruses, Chithra Chembil Sreenivasan

Electronic Theses and Dissertations

Influenza D virus (IDV) is a novel influenza virus that infects cattle and swine, with cattle as its primary host species. The goal of our first study was to investigate the replication and transmission of bovine IDV in guinea pigs. Following direct intranasal inoculation of animals, the virus was detected in nasal washes of infected animals during the first 7 days post-infection. High viral titers were obtained from nasal turbinates and lung tissues of directly inoculated animals. Further, bovine IDV was able to transmit from the infected guinea pigs to sentinel animals by means of contact and not by aerosol …

The Role Of Brand Name Fluency: A Pharmaceutical Marketing Perspective, David Wamble

Electronic Theses and Dissertations

Background: consumers are exposed to thousands of advertisements, most all of which are designed to promote a particular brand and accompanying brand name. The selection of a brand name is a critical strategic decision and is an important means to building brand equity. The importance of branding elements, specifically brand names, has led pharmaceutical manufacturers to become more creative and open the possibilities of language in brand name development. Given the complexities associated with brand name development in the U.S. pharmaceutical industry and the trends observed in recent pharmaceutical brand names, advancing the understanding of how brand name selection can …

Experimental Investigation Of Impurities And Their Effect On Acousto-Electric Properties Of Lithium Niobate, Chandrima Chatterjee

Electronic Theses and Dissertations

No abstract provided.

A Framework For Assessing Water Quality, Prioritizing Recovery Potential, And Analyzing Placement Of Best Management Practices, Tadesse Animaw Sinshaw

Electronic Theses and Dissertations

Motivated by the U.S. EPA goals, this research developed a framework to support identification and restoration of nutrient-impaired water bodies. The study objectives were developing total nitrogen (TN) and total phosphorus (TP) prediction models, evaluating the impact of social indicators on assessing recovery potential, and developing a spatial decision support system for choice and placement of best management practices (BMPS). An artificial neural network was used to develop TN and TP predictive regional models for U.S. lakes using easily measurable and cost-effective variables. The performance of models was superior for regions trained with larger datasets and/or regions with lower temperature …

A Study Of Computational Problems In Computational Biology And Social Networks: Cancer Informatics And Cascade Modelling, Christopher Ma

Electronic Theses and Dissertations

It is undoubtedly that everything in this world is related and nothing independently exists. Entities interact together to form groups, resulting in many complex networks. Examples involve functional regulation models of proteins in biology, communities of people within social network. Since complex networks are ubiquitous in daily life, network learning had been gaining momentum in a variety of discipline like computer science, economics and biology. This call for new technique in exploring the structure as well as the interactions of network since it provides insight in understanding how the network works and deepening our knowledge of the subject in hand. …

African American And First-Generation Students’ Perceptions Of And Experiences With An Academic Cohort, Kim Barnes

Electronic Theses and Dissertations

Underrepresented student populations are faced with numerous barriers and are often overlooked on many college campuses. The aim of this research was to better understand academic cohorts and if they help reduce some of the barriers faced by African American and first-generation students which can ultimately affect retention and persistence to graduation. In order to gather this information, interviews and surveys were conducted with students once enrolled in the foundations for academic success track (Fastrack) program at the University of Mississippi. Results from the interviews and surveys indicate that while the Fastrack program seemed to support successful social transitions for …

Comparisons Of Time To Task Failure And Muscle Activity For Two Different Submaximal Fatiguing Contractions, Sunggun Jeon

Electronic Theses and Dissertations

The aim of this study was to examine the time to task failure for two different fatiguing tasks (force vs. Position task) on elbow flexion exercise, in order to explore potential mechanisms of muscle fatigue. Twenty healthy and recreationally active individuals (10 men and 10 women) participated in this 3-visit investigation. At least 48 hours after the first visit as the familiarization, the subject returned for one of the experimental visits (order randomized). During the force task visit, the subject performed maximal voluntary contractions (mvcs), several submaximal trapezoid isometric contractions with different intensities (40% and 70% of mvc), and folloby …

Comparison Of Air Displacement Plethysmography And Dual-Energy X-Ray Absorptiometry For Estimation Of Body Fat Percentage In National Collegiate Athletic Association Division I Athletes, Caitlyn Rose Chenevert

Electronic Theses and Dissertations

The aim of this research is to study the Apple iOS and Android mobile frameworks from a developers' perspective. The first chapter introduces a historical overview of operating systems for mobile devices as well the motivation and objectives of the research. The second chapter introduces basic principles of the iOS and Android mobile frameworks in order to evaluate the platforms. The third chapter evaluates and compares the main features of both frameworks. The fourth chapter discusses the implementation of several applications on the iOS and Android mobile frameworks, which are used to demonstrate the advantages and disadvantages of each platform. …

The Effects Of Acidic Conditions And Tannins On The Survival, Development, And Behavior Of Cope’S Gray Treefrog (Hyla Chrysoscelis), Caleb E. Dodd

Electronic Theses and Dissertations

As amphibians decline around the world, freshwater acidification resulting from pollutants and acid rain may be a contributor. The ability of organisms to cope with environmental changes is greatly mediated by behavior, and recent studies indicate that anthropogenic acidification impairs behavioral responses by impacting olfactory abilities of aquatic organisms. Responding appropriately to novel stimuli is important for individual performance and survival, and pollutants may cause organisms to behave maladaptively. In this study I sought to: a) determine whether the oviposition site choices of adult female frogs correspond with the pH and tannin conditions that maximize tadpole survival and performance in …

Leaping Behavior In Silver Carp (Hypophthalmichthys Molitrix): Analysis Of Burst Swimming Speeds, Angle Of Escape, Height, And Distance Of Leaps, Ehlana Stell

Electronic Theses and Dissertations

Silver Carp have rapidly expanded their range exploiting vulnerable habitats, disrupting fisheries, and inflicting unknown ecological damage. These fish have continued to spread into the Middle Mississippi River and the Tennessee River Valley and great effort is being expended to prevent Silver Carp from entering the Great Lakes and expanding further into the Ohio, Illinois, Missouri, and Tennessee Rivers. Using boat-mounted cameras, we recorded in situ video of invasive Silver Carp, Hypopthalmichthys molitrix leaps to measure their horizontal distance, height, and angle of escape as well as their burst speed. Video tapes of fish leaps were obtained from populations of …

Impacts And Implications Of Polytypism On The Evolution Of Aposematic Coloration, Justin Philip Lawrence

Electronic Theses and Dissertations

Aposematic signaling is a comdefensive strategy whereby prey species use conspicuous signals (i.e., bright coloration) to warn predators of the risks of predation due to a secondary defense. Theoretical, lab, and field experiments have demonstrated that individuals who project novel conspicuous signals should experience disproportionately high predation pressure as predators will not associate novel signals with a secondary defense. Thus, aposematic signaling should be subject to strong positive frequency-dependent selection (FDS). Numerous species show considerable intrapopulation variation (polymorphism) in direct conflict with the expectations of FDS. Interpopulation variation (polytypism) can adhere to expectations of FDS, but as its origins likely …

The Relationship Between Note-Taking Method And Grade Point Average When Controlling For Act Score And Self-Regulation Ability In Undergraduate Students, Donna Lee Gurley

Electronic Theses and Dissertations

A sample of 130 students from a mid-sized research university in the southern United States were asked questions about their note-taking practices, particularly about the percentage of classes in which they had taken notes on a laptop for both the previous semester and for their entire undergraduate career. Note-taking method was then entered as an independent variable along with composite ACT score and each students' score on the Self Regulation Survey (SRS) (Schwarzer, Diehl, & Schmitz, 1999) into a multiple regression analysis to determine the extent to which there is a relationship between note-taking method and grade point average. No …

Functionality And Role Of Different Fatty Alcohols In Topical O/W Cream Formulation, Supriya Bhide

Electronic Theses and Dissertations

Fatty alcohols are excipients that are abundantly used in various pharmaceutical formulations. The objective of the present study was to evaluate the impact of incorporating different fatty alcohols on microstructural and formulation characteristics of topical o/w clotrimazole cream formulation. The formulations containing different fatty alcohols as Kolliwax® CSA 50 (CSA 50), Kolliwax® CSA 70 (CSA 70), Kolliwax® MA (MA), Kolliwax® CA (CA), Kolliwax® SA (SA) were prepared by selecting suitable RPM and homogenization time. The M.P. of API and fatty alcohols were determined using DSC technique. The prepared cream formulations were evaluated for their phase separation. The various tests like …

Polymer Based Delivery Of Doxycycline Hyclate For The Prevention Of Peri-Implant Mucositis Infection, Sagar Deepak Sawant

Electronic Theses and Dissertations

Peri-implant mucositis is a silent inflammatory condition that is destructive in nature affecting only the soft tissues in the vicinity of dental implants. The current line of treatment includes the use of systemic antibiotics, mechanical debridement using LASER decontamination, the use of mouthwash or oral rinsing with chlorhexidine, maintenance and improvement of oral hygiene, mechanical debridement with or without systemic antibiotic treatment, mechanical debridement with or without the use of local drug delivery systems. However, these treatments do not solve the problem of implant rejection as peri-mucositis progresses to per-implantitis which causes severe bone loss and ultimately leading to implant …

Armatures For Success: Advancing Racial Equity For Funeral Service Technology Students, Angela Massey Hopper

Electronic Theses and Dissertations

The purpose of this descriptive, exploratory action research study, using both qualitative and quantitative methods, was to identify students at risk of failure on a post-graduate licensure exam and to develop and implement improvement models to improve exam performance. The participants were alumni of the funeral service technology program at Northwest Mississippi Community College. African American graduates of this vocational course failed at increasingly disparate rates above Caucasian graduates in the national board licensing examination, despite commensurate post-secondary scholastic achievement. The quantitative research portion of the study statistically analyzed student performance measures in funeral service classes to reveal areas of …

Engagement Strategies And Their Impact On Underserved Students, Tonyalle Vershutte Rush

Electronic Theses and Dissertations

No abstract provided.

Engagement Strategies And Their Impact On Underserved Students, Marquis Mccloud

Electronic Theses and Dissertations

No abstract provided.

Depending On Twitter For Breaking News: A Comparison Between American And Saudi Students, Maria Zoheir Hamdan

Electronic Theses and Dissertations

This thesis aimed to measure the extent of American and Saudi students' dependence on twitter to get breaking news and how they interact with this platform in light of uses and gratifications theory. To investigate the similarities and differences between the two groups, 91 American students and 98 Saudi students participated in an online survey in spring 2018. It concluded that both American and Saudi students depend on twitter to get breaking news, and finding out what is happening is the first motivation to use twitter. While most Saudi students voted for twitter as the most important source to get …

A Body A Day: Constructing Deviance At The Mississippi State Asylum, Rachel Christine Childs

Electronic Theses and Dissertations

Though the first graves of assumed-former asylum patients were discovered at the University of Mississippi Medical Center over 25 years ago, it wasn’t until 2017 that the estimated body count—which had been rising in reports for several years—rose above 7,000. Along with national attention, the growing burial site has prompted large-scale efforts by a consortium of scientists and scholars to determine how best to utilize and memorialize the remains, and yet to date, a complete cultural study that explores the sociopolitical context which these people represent has yet to be published. Consisting primarily of archival material and interviews, my research …

Examining The Influence Of Personal And Environmental Factors On Treatment Outcomes In Opioid Dependent Medication-Assisted Treatment Patients., Vierne Placide

Electronic Theses and Dissertations

Opioid abuse has become a global epidemic and is now a huge public health concern here in the US. Non-medicinal use of opioid prescription drugs is at the forefront of the epidemic and considered the "gateway" drug to other illicit opioid use. As opioid prescribing has increased over the last decade in the US, so has opioid-related deaths, surpassing car accidents and suicide as the leading cause of injury-related deaths. Medication assisted treatment (MAT) is fundamental in decreasing opioid abuse overdose and mortality. Therefore, the research study aims to determine if counseling adherence, opioid abstinence, and retention in MATs are …

Effects Of Hydrological Connectivity On The Benthos Of A Large River (Lower Mississippi River, Usa), Audrey B. Harrison

Electronic Theses and Dissertations

The effects of hydrological connectivity between the Mississippi River main channel and adjacent secondary channel and floodplain habitats on macroinvertebrate community structure, water chemistry, and sediment makeup and chemistry are analyzed. In river-floodplain systems, connectivity between the main channel and the surrounding floodplain is critical in maintaining ecosystem processes. Floodplains comprise a variety of aquatic habitat types, including frequently connected secondary channels and oxbows, as well as rarely connected backwater lakes and pools. Herein, the effects of connectivity on riverine and floodplain biota, as well as the impacts of connectivity on the physiochemical makeup of both the water and sediments …

The Influence Of Self-Prescribed Knee Bracing On Walking In Healthy Adults, Lauren Luginsland

Electronic Theses and Dissertations

The knee is one of the most commonly loaded anatomical joints in the human body due to maintaining an upright posture. Increased joint loading can lead to various injuries which can either be treated surgically or non-surgically including immobilization by bracing. Numerous studies have looked at functional knee bracing post-operative surgery creating a gap within the literature analyzing non-operative functional knee braces within a healthy population. Commonly prescribed functional knee braces such as the Ossur Rebound® have been prescribed by physicians, but also available over-the-counter for self-prescription to assist with injury prevention, stabilization, and protection. Previous studies have looked at …

Development And Characterization Of Fluocinolone Acetonide Loaded Nanosized Lipid Carriers For Ocular Delivery Via Subconjunctival Route: Synergistic Effect Of Vitamin A Palmitate, Bhavik Soneta

Electronic Theses and Dissertations

Though nanotechnology which exploits the use of nanoparticles for therapeutic application have embarked as an emerging tool for drug delivery applications, the delivery of therapeutic molecules into deep ocular compartments has always been a challenging task. In this regard, the main objective of our current investigation was to develop and evaluate the fluocinolone acetonide (FA) loaded nanostructure lipid carrier (FA-NLC) in situ gel for improved ocular bioavailability by subconjunctival injection. FA, a corticosteroid administered for inhibiting the ocular inflammation either as intravitreal injection or as intravitreal implants. The FA-NLCs were developed by using vitamin A palmitate as one of the …

Synthesis And Characterization Of Redox-Sensitive Polymer And Prodrug For Targeted Drug Delivery, Chang-Hee Whang

Electronic Theses and Dissertations

Systemic administration of chemotherapeutics is associated with various side effects deriving from accumulation in off-target sites and acute toxicity of the drugs. In the past decade, engineering targeted drug delivery platforms arose as a novel paradigm to overcome such obstacles and ultimately achieve advanced forms of chemotherapy. This thesis reports successful syntheses of l-RSP, a redox-sensitive self-immolative polymer, and DNS-SN38, thiol-sensitive SN-38 prodrug, as potential candidates for targeted drug delivery platforms. By covalently conjugating a redox-trigger (p-nitrobenzyl alcohol) and self-immolative linker (p-hydroxybenzyl alcohol) to the cyclization spacer (n-2-(hydroxyethyl)ethylene diamine), a novel self-immolative monomer was obtained. Polymerization of the respective monomer …

A Novel Acetaminophen Soft-Chew Formulation Produced Via Hot Melt Extrusion With Inline Near-Infrared Monitoring As A Process Analytical Technology Tool, Pengchong Xu

Electronic Theses and Dissertations

People suffer dysphagia when swallowing hard tablets and capsules. Gelatin based soft chewable tablets was used as an alternative and novel drug delivery format to overcome dysphagia. But conventional method of producing gelatin based soft chewable tablets has many potential issues. The objective of this study is using glycerol and hot-melt extrusion technique to address potential issues and optimizing the formulation. Gelatin (15%), acetaminophen (30%), saccharin (1.5%), xylitol (6.5%), sodium chloride (2%) and six different ratios of water (45-0%) and glycerol (0-45%) were used in seven formulations. The extrusion process temperature of formulation 1-6 and formulation 7 were 90 ëšc …