Digital Commons Network^™

From Specialized To Generalized Frameworks: Broadening Machine Learning Approaches To Detect Natural Selection, Sandipan Paul Arnab

Electronic Theses and Dissertations

Natural selection leaves characteristic footprints in genomic variation, and detecting these patterns is fundamental to understanding evolutionary history and adaptation in humans. In this thesis, I present a progression of machine learning frameworks, beginning with highly specialized feature engineering and complex modeling, advancing to approaches that require minimal training, and culminating in methods that remain robust to model misspecification. First, I developed SISSSCO, a spectral feature extraction framework that applies wavelet transforms, multitaper analysis, and S-transform to genomic summary statistics, converting one-dimensional signals into two-dimensional spectral images analyzed by convolutional neural networks. SISSSCO achieved high accuracy across varied evolutionary scenarios, …

Posttraumatic Growth Following Pregnancy Loss: Understanding The Influence Of Positive Religious Coping And The Moderating Effect Of Perceived Social Support, Maria Alayza

Electronic Theses and Dissertations

The purpose of this research study was to examine positive religious coping, perceived social support, and posttraumatic growth (PTG) among bereaved mothers who had experienced pregnancy loss. I aimed to inform counselors about the nuances of the aftermath of pregnancy loss, as well as the protective and risk factors of PTG. The final sample consisted of 154 bereaved mothers who thoroughly completed a demographic questionnaire, the Positive Religious Coping subscale of the Brief Religious Coping Scale (Brief R-COPE), the Posttraumatic Growth Inventory–Expanded (PTGI-X), and the Multidimensional Scale of Perceived Social Support (MSPSS). I utilized the IBM Statistical Package for the …

Effects Of Aromatherapy On Promoting Sleep In Patients With Neurological Deficits, Cherylle Reed

Electronic Theses and Dissertations

Reliance on sleep aids in neurological patient population can lead to negative side effects and compromise patient safety. The purpose of this doctoral nursing project was to determine if the implementation of McDonnell and Newcomb’s aromatherapy process will reduce the incidence of sleep-promoting medication administration as compared to the current practice in neurological deficit patients over 4 weeks. A quantitative, quasi-experimental design evaluated effects on sleep quality and pharmacological sleep aids by using McDonnell and Newcomb’s aromatherapy combination of lavender, bergamot, and ylang ylang essential oils placed on a cotton ball at the patient’s bedside each night. The sample included …

Synergetics In Complex Adaptive Systems, Joseph C. Mckinley

Electronic Theses and Dissertations

Synergetics is an emerging paradigm which quantitatively describes and predicts the dynamics of complex living and nonliving systems. It has illuminated how complex systems can spontaneously self-organize by coordinating the activity of their constituent components toward some coherent, collective behavior. This coordinated activity can produce complex macroscopic spatiotemporal patterns without the need for central planning. In this dissertation, we develop and explore generalizations of the Haken-Kelso-Bunz (HKB) model of coordination dynamics. These generalizations include modeling higher-dimensional systems of coupled multistable oscillators with arbitrary diversity and coupling parameters, where the system components have the capacity to “learn” or adapt their intrinsic …

Analyzing Flexible Fillers For Enhanced Protection In Post-Tensioned Bridges, Amanda Armudi

Electronic Theses and Dissertations

Florida’s extensive coastline, dense network of bridges, and highly aggressive environmental conditions make corrosion a critical concern for the durability of bridges infrastructure. To minimize corrosion in bridge structures that use unbonded post-tension tendons, the Florida Department of Transportation (FDOT) is using flexible fillers as an alternative material to cementitious grout. This study evaluated the performance of five flexible fillers under sodium chloride (NaCl) exposure using NaCl solutions at concentrations of 10mM, 100mM and 1M over an 8-month period. Visual inspections revealed that filler composition and pre-existing cracks and voids in the filler samples significantly influenced degradation behavior. The samples …

A Quality Improvement Project To Standardize Sexual Dysfunction Screening In Primary Care, Ashley M. D’Anna

Electronic Theses and Dissertations

Sexual health is an essential aspect of overall well-being but is often overlooked in primary care due to provider discomfort, time constraints, and lack of standardized screening protocols. This quality improvement (QI) project aimed to implement a consistent approach to screening for sexual dysfunction using the Arizona Sexual Experiences Scale (ASEX), a validated five-item tool assessing sex drive, arousal, orgasm, and satisfaction. Guided by Swanson’s Theory of Caring and Pender’s Health Promotion Model, the project emphasized compassionate, patient-centered care and the promotion of health-enhancing behaviors.

Using the Plan-Do-Study-Act (PDSA) framework, the ASEX tool was incorporated into annual wellness visits following …

African American Female College Students’ Experiences At Predominately White Institutions, Sh'nita Louise Mitchell

Electronic Theses and Dissertations

African American women who attend predominantly White institutions (PWIs) have historically encountered systemic challenges that include racial isolation, microaggressions, a lack of cultural understanding, and insufficient institutional support. These barriers often impact their sense of belonging, academic persistence, and overall success. I aimed to explore the lived experiences of African American women who graduated from PWIs to understand how these women navigate institutional structures and sustain their academic journeys. I aimed to examine the unique challenges and supports experienced by African American women, and to identify factors that contribute to or hinder their persistence and success at their PWI. The …

Professor Perspectives: Inclusion Of Students With An Intellectual Disability In Transition Programming On A College Campus, Melissa Jane Massey

Electronic Theses and Dissertations

Students with intellectual disabilities (ID) are often unemployed or underemployed compared to students who do not have ID. Transition or postsecondary programming for students with ID has increased in recent years in response to the U.S. federal requirement for special education professionals to complete transition plans before students turn 16. The requirement for transition planning in Texas is age 14, and the ARD committee including the student and parent come together to develop goals for future planning. Transition plans include information on future employment, future independent living skills, and agency connections that students with ID may need to access to …

Stress Management Strategies In An Investment Firm: A Managerial Perspective, Cheri C. Nelson

Electronic Theses and Dissertations

This qualitative study examined how client relationship managers and market supervision managers in the investment industry experienced, interpreted, and managed workplace stress within the context of organizational culture, leadership practices, and available resources. Guided by the job-demands resources (JD-R) model, semistructured interviews were conducted with participants across multiple markets to investigate the interplay between high job demands, leadership behaviors, and employee well-being. Findings indicated that while trusted colleagues and positive leadership behaviors served as protective resources that reduced strain and fostered resilience, negative attitudes, favoritism, and lack of collaboration among colleagues amplified stress. Communication breakdowns, poorly managed organizational change, and …

Closing The Graduation Gap: Factors That Impact The Graduation And Enrollment Rates Of First Generation African American Male Students At Predominantly White Christian Universities, Byron C. Johnson Jr

Electronic Theses and Dissertations

First-generation African American male students encounter unique challenges on their journey through higher education. These challenges include inadequate academic preparation, limited family support, financial hardships, and difficulties in finding a sense of belonging. Additionally, factors such as race and religion present significant barriers that hinder their ability to persist in and graduate from colleges and universities without institutional support. Strategic initiatives, programs, and services that address the specific needs of these students are crucial for promoting their academic and social integration, ultimately influencing their success in higher education. This study focused on the experiences of successful first-generation African American students …

A Computational Framework For Multi-Scale Analysis Of Mouse Cerebral Blood Flow Regulation, Hadi Esfandi

Electronic Theses and Dissertations

Cerebral hemodynamic imaging is increasingly used as a non-invasive technique to study brain function and dysfunction in both research and clinical settings. Recent advances in imaging technologies have enabled high-speed, high-resolution, whole-brain measurements of blood flow and oxygenation. Improving the interpretation of these cerebral hemodynamic signals through a mechanistic understanding of their cellular drivers would enable more accurate characterization of brain function and pathology. However, no existing biophysical model fully captures the fine-grained dynamics observed in these signals. This dissertation introduces a biophysically grounded computational framework for multi-scale analysis of the mouse cerebral blood flow regulatory system, which captures mechanistic …

Investigating How Evolution Has Affected The Neuroanatomy Of Adult Astyanax Mexicanus, Peter Igwilo

Electronic Theses and Dissertations

The topology of the brain is highly conserved across phyla, yet the evolutionary processes driving anatomical divergence remain poorly understood. The fish Astyanax mexicanus, which exists in both surface- and cave-dwelling morphs within the same species, provides a powerful model for studying brain evolution. While previous studies have focused on larvae, imaging adult brains has been challenging due to their size and opacity. This study overcame these limitations using tissue clearing, light sheet imaging, and computational analysis to generate a comprehensive adult brain atlas. Using nuclear staining and antibody labeling, brain-wide 3D maps were created to compare regional size, shape, …

Comparing Ordinary Least Squares And Quantile Regression: A Causal-Comparative Approach To Modeling Conditional Relationships, Samuel Nnorom

Electronic Theses and Dissertations

Ordinary Least Squares (OLS) regression has traditionally been the preferred quantitative method for estimating linear relationships. However, it assumes that the effect of a predictor variable remains constant across the entire outcome distribution, which can miss important insights when data are heterogeneous. Quantile Regression (QR), on the other hand, offers a more detailed analysis by focusing on the full response variable distribution, thereby revealing different relationship patterns at various quantiles within the outcome. This study compares how OLS and QR perform in modeling conditional relationships within a causal-comparative framework based on ex post facto research. Using the mortality data from …

The Covid-19 Pandemic As An Environmental Jolt And Its Impact On Firms And Essential Workers, Kimberly Kay Hyett Nehls

Electronic Theses and Dissertations

Environmental jolts are sudden, large-scale disruptions that challenge organizational and societal stability and demand new ways of understanding adaptation across individuals and firms. This two-paper dissertation explores the human and organizational dimensions of such jolts through the empirical context of the COVID-19 pandemic. Paper 1 examines how global tourism firms navigated the crisis, introducing the constructs of global stakeholder interconnectedness and stakeholder prioritization fluidity to refine stakeholder theory. The findings show how international exposure shaped communication strategies under duress. Paper 2 turns to the lived experiences of low-wage essential workers, extending sensemaking theory through the concept of constrained sensemaking, highlighting …

Chronic Pain: An Exploration Of The Experience Of Chronic Pain, Andrea Alzalde

Electronic Theses and Dissertations

Chronic pain is a pervasive public health issue within Western society today and amongst humans worldwide. Although chronic pain is something that many people have or will experience sometime in their life, it is a complex experience that does not have a simple universal solution or immediate cure. The causes of pain can be a multitude of things and the treatments that work for some may not work for others. The current research seeks to explore the experience of chronic pain to help fill gaps in the wider research of pain. This study pursues answers to two research questions including; …

Centrosomal And Non-Centrosomal Microtubule Networks Coordinate To Drive Nuclear Dynamics In Developing Epithelium, Rashmi Budhathoki

Electronic Theses and Dissertations

The morphogenesis of developing tissues relies on extensive cellular rearrangements in shape, position, and identity. A key process in reshaping tissues is cell intercalation-driven elongation, where epithelial cells align and intercalate along a common axis. Typically, analyses focus on how peripheral cortical forces influence cell shape changes. Less attention is given to how inhomogeneities in internal structures, particularly the nucleus, impact cell shaping. Here, we examine how pulsed contractile and extension dynamics interact with the nucleus in elongating Drosophila embryos. Our data show that tightly packed nuclei in apical layers hinder tissue remodeling/oscillatory behaviors. We identify two mechanisms for resolving …

Role Of Nucleic Acids As Chaperones In Protein Folding, Zijue Huang

Electronic Theses and Dissertations

Many proteins have slow folding times in vitro that are physiologically untenable. To combat this challenge, ATP-dependent chaperonins are thought to possess the unique ability to catalyze protein folding. Performing quantitative model selection using protein folding and unfolding data, we here show that short nucleic acids containing Gquadruplex (G4) structure can also catalyze protein folding. Performing the experiments as a function of temperature demonstrates that the G4 reshapes the underlying driving forces of protein folding. To understand the structural basis of this catalytic activity, we introduce NMR method to solve the structures, at base-level resolution, of a multiconformer G4 with …

Influence Of Obesity On Knee Joint Mechanics: A Subject-Specific Musculoskeletal Modeling Approach, Ryan C. Knowles

Electronic Theses and Dissertations

Obesity has been consistently linked to knee osteoarthritis (KOA), a debilitating joint disease. While prior work has shown that obese individuals often walk with altered biomechanics compared to normal-weight (NW) individuals, which may accelerate KOA progression, less is known about how these mechanics affect load distribution between the medial and lateral tibiofemoral (TF) compartments, particularly during higher-demand activities. This study developed subject-specific musculoskeletal models of five obese and five NW individuals, incorporating CT-based bone measurements and individualized joint contact points. Simulations were driven by six degree-of-freedom (6DOF) kinematics obtained from high-speed stereo radiography (HSSR) to predict TF loading and associated …

Examining Whiteness: A Narrative Inquiry Into Racial Identity Among White Women In Study Abroad Programs, Audrey Moreno Townsend

Electronic Theses and Dissertations

The purpose of this narrative inquiry study was to better understand race in contexts both domestically and abroad through the perspectives and experiences of white women who studied abroad outside of Europe and the Anglosphere. The investigation explored on how these experiences shaped white women’s understanding of racial identity upon returning to their home institutions. The research question which was addressed was: How do white women experience study abroad programming? Research highlights a critical gap in existing literature on this topic. While white women are centered in the study, it is contextualized considering how People of Color experience the world. …

The Experiences Of School Psychologists Serving Students With Traumatic Brain Injuries: A Phenomenology, E. Grace Ritchie

Electronic Theses and Dissertations

Traumatic Brain Injury (TBI) is a complex experience associated with a diverse constellation of symptoms and challenges. TBI scholars have extensively explored the varying needs of youth in the aftermath of a head injury. Likewise, recent literature details recommendations for school psychological services in support of these students. Such recommendations largely reflect insights drawn from broader TBI and disability research, integrated with the established scope of school psychologists’ practice (e.g., the National Association of School Psychologists Practice Model). Nevertheless, school psychologists’ perceptions of these students’ challenges have been inadequately examined. Such perspectives are likely valuable, given school psychologists’ unique training …

Trainee Countertransference And Competency In Bereavement Therapy: Strengths And Limitations Of The Wounded Healers, Meghan Paynter

Electronic Theses and Dissertations

Countertransference is a common experience in therapy, happening among clinicians of all stages of their career and the outcomes of this experience hinge largely on how countertransference is managed. Challenging topics, such as grief, only make countertransference harder to manage effectively and the management of this experience improves with practice and time—something trainees have not yet ascertained. Given the pervasiveness of grief as a human experience, also indiscriminate in nature, the experiences of trainees experiencing countertransference are important to understand, including what is experienced, how they experience it, and how it impacts their process and self-perception of confidence and competence …

Illness Terminable And Interminable: A Lacanian Exploration Of Medical Assistance In Dying, Matthew Devine

Electronic Theses and Dissertations

More and more people worldwide are requesting euthanasia, physician-assisted suicide (PAS), or medical assistance in dying (MAiD). Arguments in favor of expanding access to MAiD tend to prioritize the rational, competent, autonomous subject who has the right to make decisions about their body, including their death. Some have argued that this perspective – common in biomedical and bioethical literature – tends to neglect the fact that requests for assisted dying involve a relational structure: a relationship between the subject who requests an assisted death and the Other to whom this request is addressed. After reviewing relevant psychoanalytic approaches to suicide …

Effect Of Histidine Tag On The Enzymatic Activity Of Pseudolysin And Its Interaction With The Streptomyces Metalloprotease Inhibitor (Smpi) Protein, Adewale Adeboye Adewole

Electronic Theses and Dissertations

Pseudolysin (PLN) protein is a major virulent factor in Pseudomonas aeruginosa infection. PLN belongs to the family of zinc-dependent metalloproteases. It is naturally inhibited by a smaller protein called streptomyces metalloprotease inhibitor (SMPI), secreted by Streptomyces nigrescens. Previous and current studies demonstrate that the interaction between PLN and SMPI offers unique mechanistic insights for drug development against infections caused by P. aeruginosa. This study investigated the effect of N-terminal Histidine (His) tag on the enzymatic activity of PLN and its interaction with SMPI. His-tagged PLN and SMPI proteins were expressed in bacteria and purified by affinity chromatography …

The Protective Role Of Resilience In Indirect Aggression Perpetration And Victimization, Amelia Klass

Electronic Theses and Dissertations

This study examines the relationship between resilience and indirect aggression, specifically relational and social aggression, utilizing a sample of 104 females aged 18–22. Indirect aggression, characterized by behaviors such as social exclusion, gossip, and manipulation, is associated with significant emotional and interpersonal difficulties. Using a theoretical basis that includes gender schema theory, social learning theory, and social information processing theory, this study investigates whether resilience has a significant relationship in both the perpetration of and victimization through the use of indirect aggression. Participants completed self-report measures, including the Adult Resilience Measure – Revised and the Young Adult Social Behavior Scales …

Collecting The Strands: A Psychoanalytic Study Of Hair-Pulling In Women, Jacklyn Corsitto

Electronic Theses and Dissertations

This dissertation investigated compulsive hair-pulling (i.e., trichotillomania) in women from a psychoanalytic perspective. The assumption, from a psychoanalytic viewpoint, is that the symptom of hair-pulling serves meaningful, and multiple, psychical purposes that should be analyzed rather than immediately removed, as would be the case in the current gold standard of treatment—behavioral therapy with habit reversal training. This behavioral modality leaves little to no room for exploring the historical, relational, symbolic, and emotional dimensions of hair-pulling. This dissertation fleshed out these dimensions and investigated what hair-pulling was doing for the individual, what its function or purpose was, and, indeed, what ideational …

Identifying The Experiences And Perceptions Of School Psychologists On Racial Disparities In Autism Spectrum Disorderidentifying The Experiences And Perceptions Of School Psychologists On Racial Disparities In Autism Spectrum Disorder, Anna Marie Paolicelli

Electronic Theses and Dissertations

This paper investigates the experiences and perceptions of school psychologists who identify as experts in autism spectrum disorder (ASD) regarding racial and ethnic disparities in ASD identification. Utilizing a convergent embedded mixed-methods design grounded in Consensual Qualitative Research (CQR), the study explores how school psychology practices may have contributed to recent changes in ASD outreach and assessment, as well as persistent disparities, particularly for Black children with co-occurring intellectual disability (ID). Thirteen credentialed school psychologists with extensive experience in diverse educational and clinical settings participated in semi-structured interviews and binary survey items. Findings reveal perceived progress in ASD awareness and …

Modeling Diameter Distribution Of Loblolly Pine Plantations In Response To Mid-Rotation Thinning Treatments And Assing The Economic Returns In Western Gulf Coastal Plain, Pragya Rijal, Yuhui Weng, Anusha Shrestha, Jason Grogan

Electronic Theses and Dissertations

The influence of thinning regimes incorporating row thinning on diameter distribution and timber product allocation is of considerable importance in the management of loblolly pine (Pinus taeda) plantations within the Western Gulf Coastal Plain. This study utilized data from a thinning study plots established by the East Texas Pine Plantation Research Project across East Texas and Western Louisiana. A two-parameter Weibull distribution was used to model diameter distributions under varying thinning intensities, with parameter estimation conducted using both parameter prediction (PPM) and percentile-based (PRM) methods. The PRM approach demonstrated excellent model performance, with coefficients of determination (R²) ranging …

Evaluation Of A Forest Restoration Strategy On Small Mammals In Southern Pine Ecosystems, Gage R. Grantham, Jessica L. Glasscock, Christopher M. Schalk, Kathryn R. Kiid, Reuber Antoniazzi

Electronic Theses and Dissertations

Industrial forestry replanted historic native pine forests (e.g., longleaf pine [Pinus palustris] and shortleaf pine [Pinus echinata]) to homogenous, high-density plantations consisting of native off-site species (e.g., loblolly pine [Pinus taeda]) after intensive harvesting for wood products. The contemporary forest structure that remains, consisting of off-site overstory compositions, can potentially serve as an ecological bridge to facilitate a gradual transition to a more desirable canopy species, thereby conserving biodiversity and ecosystem function. Understanding disturbance-sensitive small mammal communities from restoration strategies (retention) can help achieve long-term management goals for ecosystem conservation across larger scales. I …

Using Silvopasture To Mitigate Heat Stress In Grazing Beef Cattle, Sydney L. Lofland

Electronic Theses and Dissertations

This study evaluated the impact of silvopasture on mitigating heat stress in grazing beef cattle by comparing physiological and behavioral responses between shaded and non-shaded pastures. Twenty-two multiparous cows were monitored over a 20-day summer trial in East Texas. Data were collected on respiration rate, heart rate, heat stress scores, and behaviors including eating, ruminating, walking, and resting. Average respiration rates and behavior proportions did not differ significantly between treatments. Afternoon periods showed peak physiological stress across all cattle, but silvopasture appeared to buffer extreme responses. Although limitations such as data gaps and a shortened trial impacted interpretation, findings suggest …

Evaluating Quadrupedal Locomotion In Bats: A Geometric Morphometric Comparison Of Vertebral Adaptations Across Mammals, Jessica Upham

Electronic Theses and Dissertations

Flight is the primary locomotion of bats, while quadrupedal locomotion is not often observed and is widely variable among bats. Frugivorous bats in Pteropodidae are more efficient climbers than frugivorous bats in Phyllostomidae and insectivorous bats in Vespertilionidae, while phyllostomids and vespertilionids are better at walking on horizontal surfaces. The aim of this study is to investigate whether bats with differing modes of nonflight locomotion also exhibit disparity in thoracolumbar vertebral morphology. Using geometric morphometrics, we compared the thoracolumbar vertebral shapes of these bat families with other terrestrial and arboreal mammals. The results revealed distinct vertebral shapes among bat families …