Digital Commons Network^™

Creating New Points Of Access: How Integrating Black Acting Methods Strengthens The Western Theatre Canon., Darrin Edward Dispenza-Mosley

Electronic Theses and Dissertations

Western acting techniques have historically disregarded the contributions and techniques of black and non-Western performance to the detriment of black actors. This disregard has created barriers for black actors when engaging in what has now become standard theatre training. This training is enforced by implementation of acting techniques in academia that favor codified techniques of Eurocentric acting. Despite black acting techniques being codified and taught within the black community and academia, outside of a few historically black colleges and universities (HBCUs), predominately white academia has implemented valuable training methods that black/African American Acting techniques can offer. By looking at American …

Student Perceptions Of School Climate And Safety After The Collective Trauma Of Covid-19 And Racial Injustice Syndemic., Amy Catherine Lyons

Electronic Theses and Dissertations

For people in marginalized communities, particularly the Black and African American community, the combined, disproportionate damage and loss from of the pandemic and a cacophony of racial injustices offer cause for labeling the phenomenon a syndemic. Syndemic is defined as “a conceptual framework for understanding diseases or health conditions that arise in populations and that are exacerbated by the social, economic, environmental, and political milieu in which a population is immersed” (Singer et al., 2017, p. 881). The purpose of this study is to explore, describe, and analyze Kentucky students’ perceptions of school climate and safety by demographic groups, racial …

Biomechanical Assessment Of Fracture Risk In Young Children With Healthy Bone And Osteogenesis Imperfecta., Keyonna Mckinsey

Electronic Theses and Dissertations

Osteogenesis imperfecta (OI) is a group of genetic bone disorders that can range from a mild increase in fractures in one’s lifetime to perinatally lethal. Biomechanical assessment via finite element analysis (FEA) can be used to provide subject specific evaluation of fracture risk and thus aid in furthering understanding of likelihood of fracture due to loading associated with common daily activities. Thus, the purpose of this dissertation research was to characterize the risk of femur fracture in young children with OI compared to that of healthy children when exposed to loading associated with common activities, specifically gait. To accomplish this, …

Studies Of Pathways To T2d And Interventions Through A Dynamical System Model., Rafiqul Islam

Electronic Theses and Dissertations

Existing mathematical models investigating the progression of type 2 diabetes (T2D) over time primarily focus on glucose, insulin, β-cell mass, and other related factors, while often omitting fatty acids (FA) as an explicit variable—despite FA being a major energy source for the body. There exists a complex network of dynamical interactions among glucose, insulin, FA, and β-cell mass. To gain deeper insights into the metabolic dynamics and pathophysiology of T2D, it is essential to incorporate FA into such models. In this study, we extend the classic Topp’s GIβ model by explicitly incorporating FA and exploring its interactions with glucose, insulin, …

Cns-Specific Hiv Reservoir Characterization In Humans: Advancing Our Understanding Through Novel Genomics Methods., Ghazal Sadri

Electronic Theses and Dissertations

The persistence of the human immunodeficiency virus (HIV) reservoir despite years of suppressive antiretroviral therapy (ART) represents the principal obstacle to achieving a functional cure. Because the intact, replication-competent portion of the reservoir drives viral rebound after treatment interruption, HIV cure strategies must specifically identify and target cells harboring these proviruses. Conventional reservoir‐characterization techniques typically require separate assays to capture integration sites, assess proviral integrity, and quantify clonal proliferation and they rely on short‐read sequencing. These limitations hinder our ability to understand how integration landscapes, the integrity of the HIV genome, and cell‐division dynamics intersect to maintain viral persistence in …

Untitled: Study., Annabela Cockrell

Electronic Theses and Dissertations

Untitled: Study is an exploration into “The Work”, which is a constant evolution of the idea of the same piece. Every new work is an evolution of the one before. Previous works are often reworked and self-cannibalized into the next generation. The Work will never be presented the same way twice. There is a temporality in making and installing the work this way, what with the form, the space, the ness of it never being the same. All the while conflicting by being viewed as being the same in the same breath.

Mechanisms Of Particulate Hexavalent Chromium-Induced Inhibition Of Homologous Recombination Repair: Targeting The Bcdx2 Complex Considered Through A One Health Perspective., Aggie W. Brownell

Electronic Theses and Dissertations

Lung cancer remains the leading cause of cancer death, often linked to smoking. However, smoking alone does not account for all cases. Exposure to environmental metals like hexavalent chromium [Cr(VI)] also contributes to lung cancer. Cr(VI) causes lung cancer by inducing chromosome instability (CIN), an early hallmark of its carcinogenic mechanism. While it has been established that Cr(VI) induces chromosome instability, the precise mechanisms underlying the chromosome instability are poorly understood. This dissertation investigates the mechanisms of carcinogenesis associated with zinc chromate, a particularly potent particulate form of hexavalent chromium. Studies show Cr(VI) induces DNA double-strand breaks and impairs the …

Light Without Memory., John Day

Electronic Theses and Dissertations

This collective work and thesis sought to remedy a fragmented sense of self in the wake of addressing trauma (Personal and generational) through therapy and diagnosis. Visualizing the experience of isolation and loss through deterioration of gelatin and pixels, it exposes the fragility of memory and our tools of preservation in the presence of time. While the images of my family, past and present, cannot speak, they can activate memory evoking a desire to foster relationships with those closest to us. As I explore my identity through family photographs, I find myself embodied within them. Fragments of a whole, bound …

Healthcare Utilization Patterns, Associated Factors, And Readmission Rates Among Children With Sickle Cell Disease., Daniya Mohammed Sabrah

Electronic Theses and Dissertations

Sickle Cell Disease (SCD) is common in Saudi Arabia, with a prevalence rate of 2.3%. It is an expensive disease to manage due to the extensive utilization of healthcare resources, including hospital readmissions, extended hospital stays, and frequent emergency department visits, which cost approximately $395 million annually in U.S. dollars. The primary objective of this study was to conduct a systematic literature review of healthcare utilization and cost of patients with SCD, following the PICO framework and PRISMA guidelines. The second aim utilized count models, including the negative binomial and Poisson, to identify factors associated with emergency, inpatient, and outpatient …

Catholic High School Principals’ Experiences With Parent-School Relationships And Perceptions Of Self-Efficacy., Alexander J. Glaser

Electronic Theses and Dissertations

Principals feel overworked in part due to their responsibilities and the demands of the modern educational institution. Furthermore, dynamics between schools and parents are changing in an increasingly polarized climate. Catholic schools face a unique challenge as school choice is more prevalent and client pools become more diverse. Understanding self-efficacy is elemental to building resiliency in principals leading schools in the current climate. Through this mixed-methods phenomenological study, I sought to understand Catholic secondary school principals’ levels of self-efficacy in daily tasks and determine how parent-school relationships explain these perceptions. I used descriptive data and interviews which led to several …

A Sacrifice On The Altar Of Unity: The Loss Of Black Identity In The Unification Of Kynett And Lagrange First Umc., Rebecca Sue Wishnevski

Electronic Theses and Dissertations

This study examines the 1996 merger of Kynett United Methodist Church, a historically Black church, and LaGrange First United Methodist Church, a traditionally White church in LaGrange, Kentucky. The study provides insight into nonurban Black churches, showing that while they may have smaller congregations in smaller towns, the Black church remains central to Black life and connection like its urban contemporaries. Methods for collecting primary source material relied heavily on oral histories performed by the researcher with Black and White individuals attending said churches and their experiences during the merger. The study reveals that although unification promised a modern building …

Integration Of Multi-Omics Datasets Evaluating Structural And Functional Features Of The Gut Microbiome In People With Hiv (Pwh)., Aakarsha Vijayakumar Rao

Electronic Theses and Dissertations

Gut dysbiosis characterized by reduced abundance of beneficial butyrate-producing bacteria has been independently linked to HIV-1 infection and heavy alcohol drinking. Further, gut dysbiosis results in loss of gut barrier integrity, microbial translocation and host-specific systemic inflammation. Therefore, to evaluate the functional consequences of structural changes in the gut microbiome, integrated data analysis is imperative. In this dissertation, we perform integrated analyses using data from multi-omics platforms to examine the structural and functional features of the gut microbiome of PWH. Gut microbiome composition was evaluated by sequencing V4 region of 16S rDNA, concentrations of metabolites and host-specific immune markers were …

Differences In Prostate Cancer (Pca) Stage At Primary Diagnosis And Pca-Specific Mortality Among Rural Versus Urban Populations In Kentucky., Chase Herrmann

Electronic Theses and Dissertations

Kentucky Cancer Registry (KCR) prostate cancer (PCa) cases between the years of 1994 and 2021 were analyzed to examine differences between rural and urban populations’ primary stage at diagnosis and PCa-specific mortality. After adjusting for covariates, rural populations did not experience significantly higher odds of stage 3 diagnosis when compared to urban populations (OR = 1.02, 95% CI = 0.95 – 1.06). Rural populations had 16% increased odds of stage 4 diagnosis when compared to urban populations (OR = 1.16, 95% CI = 1.10 – 1.23). Rural populations had a 17% increased rate of PCa-specific death when compared to urban …

The Light Farm., John Wrestling Brewster Clay

Electronic Theses and Dissertations

The Light Farm is a creative examination of the convergence and divergence of truth and meaning, told in a collection of three short stories that both supplements, and is supplemented by a thesis exhibition of fine art. These stories are told using an episodic format that facilitates world building across time periods, while the sculptures, photographs, and text within the exhibition function as a physical entry point into a space in which the line between fact and fiction is tested. The impetus for this project was a lifelong interest in the disorderly confluence of corporatism, power, mortality, morality, human potential, …

Investigating The Effect Of Fasting On Senescent Cells In Nothobranchius Furzeri Fish, Israel A. Akinola

Electronic Theses and Dissertations

Senescent cells (SCs) have been documented to accumulate with age in the organism. Recent studies have shown that reducing the number of SCs in an organism result in tissue rejuvenation and extension of life expectancy. Intermittent fasting is reported to have multiple health benefits and is speculated to reduce the burden of SCs. Nothobranchius furzeri are a new model organism for studying aging and for which there are short- and long-lived strains available. We hypothesize that long- and short-lived strains of N. furzeri will accumulate SCs at different rates; and that fasting will reduce the burden of SCs.

The results …

5g Network Slice Vulnerabilities And Exploit Chaining Through Enablers, John Breeden

Electronic Theses and Dissertations

Network slicing provides fundamental support for the enhanced features of 5G. Network slicing enablers, such as software-defined networking and network function virtualization facilitate the separation of the physical distributed infrastructures and the functions that create isolated slices. With this framework, the network slice is no longer under the control of a single entity. Multiple infrastructure providers share responsibility for the slice. The 5G architecture derives from multiple services, distributed over great distances, and managed by multiple parties. Each enabler and provider adds vulnerability to network slicing. We examine the interweaving of these enablers to identify vulnerabilities, discuss potential mitigation, and …

Investigating Exoneration Patterns Among Juveniles, Kristin Mahan

Electronic Theses and Dissertations

Exoneration from crime has been studied among adults, but exoneration of juveniles (i.e., persons under age 18) has not been analyzed as a separate entity, despite distinct legal systems and developmental considerations. Wrongful conviction, while not always indicative of innocence, devastates lives of convicted individuals and their families, while increasing public mistrust and sometimes failing to convict truly guilty individuals. This devastation, as well as vulnerability to wrongful conviction, is significantly increased for youth who miss out on crucial developmental years, milestones, and opportunities.

In the current study, I examined differing and intersecting contributors (i.e., individual characteristics, crime characteristics, legal …

Movement Ecology Of Sandhills Chub, A Carolina Endemic, Zachary Adam Ramsey

Electronic Theses and Dissertations

Fish movement studies have traditionally focused on species that support commercial and recreational fisheries, but recently more focus has been given to non-game, stream fishes because of their recognized importance in maintaining biodiversity within these ecosystems. Stream fish movement is described as being “restricted” and following a leptokurtic distribution via diffusive spread related to environmental and biological factors. Many studies of stream fish movement ecology in North America have occurred in high-gradient streams with coarse substrate in mountains or in streams of the interior plains. Sandhills streams of the southeastern USA are characterized as warm-water, low gradient, and dominated by …

Heterotopias Of Confinement: Zoo Architecture And The Loss Of Elephant Agency, Clayton Gill Beasley

Electronic Theses and Dissertations

Zoos functions as a site where human-animal relationships are structured through built environments that mediate control and representation. This study examines zoos as heterotopias—spaces where power and surveillance are negotiated between human observers and captive nonhuman animals. While zoos are often framed as spaces of conservation and education, their architectural design reinforces hierarchies of observation and confinement, shaping both human perceptions of nature and the lived experiences of nonhuman animals. This research focuses on Asian elephants as a critical species within this framework, exploring how their captivity illuminates tensions between human-imposed structures and nonhuman autonomy. Drawing from theories of heterotopia, …

Leveraging Ai For Enhanced Multimedia Content Creation: College Students’ Perception On The Innovation, Georgina Amankwa

Electronic Theses and Dissertations

Artificial Intelligence (AI) has revolutionized multimedia content creation, enhancing efficiency and personalization. However, this rapid evolution has raised concerns about originality and ethical responsibility. This study explored college students’ perceptions of AI in content creation and its implications. Using a mixed-methods approach, the research combined surveys and qualitative insights to analyze how students engaged with AI tools. Findings revealed that while AI streamlined workflows, improved content quality, and boosted audience engagement, concerns about authenticity, intellectual property, and the diminishing role of human creativity persisted. Statistical analyses showed a strong correlation between frequent AI use and perceived benefits, yet ethical dilemmas …

Coalitional Belonging As Praxis: First-Year Writing And Student Community Creation In The Post-Dei University., Kendyl C. Harmeling

Electronic Theses and Dissertations

This dissertation began as a study into how students interpret and engage language and actions from their institutions of higher education which allege to be supporting and supportive of universally diverse, equitable, and inclusive campus community belonging. Occurring within a locally and globally turbid context of exponential and variable challenges to diversity, equity, and inclusion efforts by institutions of power – like those of higher and public education – this dissertation seeks to understand how, within and without institutional support for DEI, students self-sponsor and community-sponsor their ways of knowing and being to claim space for their belonging on campus. …

Preparing For Inevitable Uncertainty : Collaborative Sensemaking Of Assets And Barriers To Becoming A Jewish Supplementary School Educator., Mindy M. Gold

Electronic Theses and Dissertations

While teacher shortages are a shared national challenge, responses are shaped by local nuances (McHenry-Sorber et al., 2019). This research explored how community-identified assets might address teacher recruitment challenges in supplementary Jewish education programs, a microcosm of public education. Many Jewish supplementary schools are investigating curricular and programmatic approaches to attract students and families without commensurate inquiry into attracting teachers to the field. The disproportionate focus has occurred amidst a shrinking pool of candidates (Rosov Consulting, 2021b). In this study, I asked: What do supplementary Jewish education school community members see as assets/barriers to recruiting educators in their school community? …

I'M Still Eating Crayons., Eisey Eisenhardt

Electronic Theses and Dissertations

im still eating crayons serves as a reflection on past events experienced in trying conditions after many years of rumination. The title itself is derived from my childhood inclination towards physically experiencing color and texture via chewing on crayons. An inclination that I still experience today; a wish to chew on what captivates me and break it down over time within, so that I may discover a deeper connection with those objects, ideas, and concepts. Not all made discoveries were victories, nor do they place my conscious in a better position than it was at the height of my past …

Emotion Regulation, Reasoning, And Procedural Safeguards In Politically-Polarized Moral Dilemmas., Alanea Graci

Electronic Theses and Dissertations

Societal disputes often stem from polarized moral dilemmas. Procedural justice and self-determination (PJSD) afforded by societal decision-making processes may influence cooperation and acceptance in these dilemmas. However, moral conviction can sometimes overshadow PJSD, causing morally-opposed individuals to avoid deliberation, become uncooperative, or reject decision outcomes. I conducted two experiments to explore the role emotions (emotion regulation) and procedural safeguards for democratic deliberation (e.g., equal discussion time, rules for civility) play in these situations. I examined the topic of abortion in the U.S. after the Supreme Court’s June 2022 reversal of Roe v. Wade. Undergraduates at a large, urban Midwestern university …

Early College Credit Programs As Predictors Of Postsecondary Student Success., Emily K. Spoden

Electronic Theses and Dissertations

Early college credit programs (ECCPs), such as AP, dual enrollment, and IB programs, were created to provide more challenging college-level coursework to academically advanced high school students. Educators and policymakers have encouraged high school students to participate in these programs with the goals of being prepared academically for college, saving money on tuition by earning college credits early, and speeding up time to postsecondary graduation. The purpose of this study was to examine likelihood of postsecondary first-year retention and graduation timeframe as a result of participating in — and earning credits from — these programs. Participants of this study included …

Translation Of The Carcinogenic Dna Breakage-Repair Inhibition Mechanism For Hexavalent Chromium To Its Key Targets: Lung Epithelial Cells, Lung Tissue And Impacts On The Genome., Idoia Meaza Isusi

Electronic Theses and Dissertations

Lung cancer is the leading cause of cancer death worldwide. Hexavalent chromium [Cr(VI)] is a human lung carcinogen with widespread occupational and environmental exposure. Despite the known health risks, how Cr(VI) causes lung cancer remains unclear. This dissertation investigates the mechanisms of Cr(VI)-induced carcinogenesis. Cr(VI) causes DNA damage, specifically DNA double strand breaks, and inhibits homologous recombination repair, a high-fidelity repair pathway. Unrepaired DNA double strand breaks or those repaired through error-prone pathways, progress to chromosomal damage, and chromosome instability. The latter is a common characteristic of Cr(VI)-exposed cells, and a hallmark of lung cancer. Although the mechanism of Cr(VI)-induced …

Healthcare Access And Agency In Material Culture: A Specialized Analysis Of Pharmaceutical Artifacts From Louisville’S West End., Sara Marian (Deurell) Ignacio

Electronic Theses and Dissertations

The American Victorian Period of the 1870s to 1920s was a time of significant transitions in medicine. In Louisville, Kentucky, this period saw an influx of Black healthcare professionals and the founding of Louisville National Medical College, the state’s first medical school open to people of color. A number of these professionals lived and/or practiced in the Beecher Terrace study area, which was excavated between 2017 and 2020. Patent medicine brands and archival records were examined qualitatively in order to understand neighborhood and case study household health concerns and consumer choice. Statistical analyses of the medicine bottles recovered during the …

Sex-Based Differences In Osteoarthritis In Early Medieval Spain: A Case Study From Visigoth And Carolingian Period Terrassa., Jordan Chatellier

Electronic Theses and Dissertations

Beginning in 1995, individuals from the Sant Pere church complex in Terrassa, Spain were exhumed. Using 21 biological females and 32 biological males collectively between the Visigoth (5^th – 8^th centuries) and Carolingian (9^th – 11^th centuries) periods from this collection, this research examined the difference in osteoarthritis between estimated phenotypic sexes. For osteoarthritis to be present, an individual needed to meet one of two criteria: 1. two or more of the following was present: macroporosity, sclerotic bone, joint deformation, and marginal osteophytes, or 2. eburnation had occurred. Through employing embodiment theory, along with gender and …

Tel Jezreel's Medieval Crusader Cemetery: A Case Study In Contemporary Burial Practices And Necroviolence Against Infants And Children., Autumn Koehling

Electronic Theses and Dissertations

The 1990s excavation of the archaeological site of Tel Jezreel in the modern nation state of Israel yielded the remains of fifty infants and children, associated with the contemporary Medieval Crusader Church. The Church, built by Knight’s Templar from the Frankish Kingdom served the occupants of Tel Jezreel from the 11^th to the 13^th century and introduced Western Christian burial practices to the local Syriac-Palestinian Christian inhabitants. Burial practices from the surrounding region of the Levant and beyond, into Crusader European cultures, show different forms of burial treatment for infants and children that can be used to understand …

Implementation Of A Sustainability Dual Credit Course Curriculum To Support Environmental Literacy In An Urban High School., Rachelle Wood

Electronic Theses and Dissertations

This bound case study examined the curricular support of Environmental Literacy in urban high school through the implementation of authentic environmental education experiences through a Sustainability Dual Credit course. Environmental Education provides students opportunities to engage in authentic local and global issues that exist beyond the classroom walls. Environmental Education is essential for students to become environmentally literate, where they are empowered to make sustainable choices that contribute to a sustainable future. A review of literature revealed there is a gap in current literature regarding how the curriculum of Sustainability Dual Credit courses supports Environmental Literacy in a United States …