Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Electronic Theses and Dissertations

Discipline
Institution
Keyword
Publication Year

Articles 1681 - 1710 of 3226

Full-Text Articles in Entire DC Network

Intramuscular Anabolic Signaling And Endocrine Response Following Different Resistance Exercise Protocols In Trained Men, Adam Gonzalez Jan 2015

Intramuscular Anabolic Signaling And Endocrine Response Following Different Resistance Exercise Protocols In Trained Men, Adam Gonzalez

Electronic Theses and Dissertations

The mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway appears to be the primary regulator of protein synthesis and growth. While resistance exercise paradigms are often divided into hypertrophy (HYP) and strength (STR) protocols, it is unknown whether these protocols differentially stimulate mTORC1 signaling. The purpose of this study was to examine mTORC1 signaling in conjunction with circulating hormone concentrations following a typical lower-body HYP and STR resistance exercise protocol. Ten resistance-trained men (24.7±3.4y; 90.1±11.3kg; 176.0±4.9cm) performed each resistance exercise protocol in a random, counterbalanced order. Blood samples were obtained at baseline (BL), immediately (IP), 30 minutes (30P), 1 …


Women And Time: Food Work Politics Of Self Defined Healthy Men, Juan Barredo Jan 2015

Women And Time: Food Work Politics Of Self Defined Healthy Men, Juan Barredo

Electronic Theses and Dissertations

This study examined the way gender operates in relation to time within the food work spectrum discussed in 19 narratives. The 19 narratives came from individual open ended face-to-face interviews with self-defined healthy men who shop at healthy food stores. This study's examination of how gender operates in the narratives was based on how the men constructed their experiences with women and work in relation to time through the food work spectrum. Women mentioned in the sampled narratives taught the men how to shop and eat in a healthy manner but women still did the cooking. Work wise the findings …


Central Florida Educational Leaders' Professional Perceptions Of Race To The Top Components Concerning Teacher Evaluation And Compensation, Orin Smith Jan 2015

Central Florida Educational Leaders' Professional Perceptions Of Race To The Top Components Concerning Teacher Evaluation And Compensation, Orin Smith

Electronic Theses and Dissertations

This mixed-methods replication study was conducted to develop further understanding of the professional perceptions of educational leaders as to the fairness and impact of Race to the Top reforms concerning teacher evaluation and compensation on student achievement and growth. Graduate students in education and educational leadership from a target university were selected to complete an electronic survey to collect quantitative and qualitative data for analysis. Quantitative results from the electronic survey revealed limited diversity in professional perceptions of the five identified components of RTTT based upon professional classification or percentage free and reduced lunch population at the school sites where …


Novel Delivery Systems For Iron Replenishment, Naresh Modepalli Jan 2015

Novel Delivery Systems For Iron Replenishment, Naresh Modepalli

Electronic Theses and Dissertations

Iron is an integral part of hemoglobin and essential for the production of red blood cells. Iron deficiency and the resulting anemia are major nutritional deficiency disorders. The majority of patient populations suffering from iron deficiency anemia (IDA) are women of child bearing age and children of all ages. Iron deficiency is a complication of various other chronic conditions. Oral iron salts or colloidal parenteral iron formulations are treatment options for iron replenishment since several decades, but they are associated with severe side effects along with other patient noncompliance issues. Transdermal delivery of iron could be a potential alternative to …


An Examination Of Factors That Contribute To Binge Eating Among Bariatric Patients, Erin Neuman-Boone Jan 2015

An Examination Of Factors That Contribute To Binge Eating Among Bariatric Patients, Erin Neuman-Boone

Electronic Theses and Dissertations

Binge eating is the most common eating disorder among individuals presenting for bariatric surgery. The majority of patients with pre-surgical binge eating experience a short-term reduction in binge eating symptoms following surgery. However, binge eating symptoms can re-emerge. This quantitative study examined variables related to and predictive of binge eating within the bariatric patient population. Specifically, the purpose of this study was to determine whether daily hassles, uplifts, depression, pre-surgical binge eating, time since surgery, and weight regain were predictors of binge eating within the bariatric patient population. One hundred and twenty-six participants completed either an electronic or paper version …


Techniques For Estimating The Variance Of Specific Estimators Within Complex Surveys, Laura Marie Galiardi Jan 2015

Techniques For Estimating The Variance Of Specific Estimators Within Complex Surveys, Laura Marie Galiardi

Electronic Theses and Dissertations

The objective of this thesis is to present the various procedures for estimating the variance of specific statistics obtained from different types of survey designs, leading up to more advanced designs such complex surveys. The thesis starts with defining the various sampling designs that are to be used for illustrations (Ch 2). Chapter two gives further descriptions of how various sampling designs are performed (from simple designs to not so simple) and shows the sophistication in calculating the estimates and variances. Chapter three cites the actual equations necessary for estimating the variances of the statistics for each design and demonstrates …


Oviposition Site Selection By Mosquitoes: Predator-Released Kairomones And Responses To Different Taxa, Lauren Larea Eveland Jan 2015

Oviposition Site Selection By Mosquitoes: Predator-Released Kairomones And Responses To Different Taxa, Lauren Larea Eveland

Electronic Theses and Dissertations

Oviposition site selection is a critical reproductive behavior for egg-laying organisms that offer little to no parental care. Determining the mechanisms females use to assess sites is critical to understanding life history traits, community structure, and species interactions. Mosquitoes are excellent model organisms for studying oviposition site selection for numerous reasons: 1) a poor decision can lead to zero reproductive success, 2) females actively assess and choose among habitat patches when locating an oviposition site, 3) larvae remain in the habitat where they hatch until they metamorphose, and 4) they lay conspicuous egg rafts that allow direct assessment of oviposition. …


I Eat Shit Food And Am Not Worthy: Negotiating The Queer Weight Of "White Trash" Embodiment In Dorothy Allison's Corpus, Rebecca Albright Jan 2015

I Eat Shit Food And Am Not Worthy: Negotiating The Queer Weight Of "White Trash" Embodiment In Dorothy Allison's Corpus, Rebecca Albright

Electronic Theses and Dissertations

This thesis argues that Dorothy Allison’s work—and specifically the women who hate me (1983), Trash (1988), and Skin: Talking about Sex, Class, and Literature (1994)—explores the unexpected alliances and radical difference and desire produced by interactions between fatness, queerness, and “white trashiness” on the terrain of late-twentieth-century representational and lived southern culture, and specifically how queer and “white trash” embodiments are both legible in terms of fatness, much in the way that gravy thickens in Allison’s writing to envelop and signify simultaneously lack and excess, shame and ecstasy, disgust and desire, and difference and community. Indeed, it is in the …


The Evaluation Of Chromium Propionate Supplementation On Insulin Responsiveness In Finishing Steers And Energy Status In Newly Weaned Steer Calves, Zachary K. F. Smith Jan 2015

The Evaluation Of Chromium Propionate Supplementation On Insulin Responsiveness In Finishing Steers And Energy Status In Newly Weaned Steer Calves, Zachary K. F. Smith

Electronic Theses and Dissertations

A series of experiments were conducted to evaluate the influence of supplemental dietary chromium (0 or 400 ppb) on insulin responsiveness in finishing steers (Exp 1. and Exp 2.), and energy status in newly weaned steers upon introduction to the feedlot (Exp 3.). To evaluate insulin responsiveness, two models were used with finished steers of different ages: Exp 1. 12 steers; 24 mo old (BW=783 ± 29 kg); and Exp 2. 24 steers; 14 mo old (BW=625 ± 24 kg). A jugular infusion of insulin (0.45 IU bovine insulin/ kg of BW0.75, INS) was pulse dosed 2 h post-prandial. A …


Effect Of Timing Of Artificial Insemination And Estrus Expression Using Sexed Semen On Pregnancy Rates In Holstein Dairy Cows, Stephen Crego Jan 2015

Effect Of Timing Of Artificial Insemination And Estrus Expression Using Sexed Semen On Pregnancy Rates In Holstein Dairy Cows, Stephen Crego

Electronic Theses and Dissertations

The use of sexed semen has become important in dairy herds across the U.S. but reported lower conception rates have limited the adaptation in some herds. The objective of this study was to determine if timing of AI and expression of estrus impacted fixedtime AI pregnancy success with sexed semen. Primiparous and multiparous lactating Holstein cows, were synchronized with a Presynch-Ovsynch protocol (PGF d -29; PGF d -19; 100μg GnRH and CIDR insertion d -9; PGF and CIDR removal d -2; GnRH d 0) starting at 35 DIM. The cows were allotted into a 2 x 2 factorial design with …


Farm To Fork: A Culinary- And Farm-Enhanced Nutrition Education Program, Vivian Ray Jan 2015

Farm To Fork: A Culinary- And Farm-Enhanced Nutrition Education Program, Vivian Ray

Electronic Theses and Dissertations

With obesity in adolescents becoming a major health problem in the United States, there has been an expansion in the use of nutritional education programs as intervention. Effective nutrition education can decrease the incidence of obesity and other diet-related chronic diseases, type-2 diabetes, cardiovascular disease, and hypertension. This dissertation in practice proposes to design a nutrition education program, integrating farm and culinary activities into a nutrition education curriculum. The program is designed as a stand-alone program, but for this practice, implementation integrates the nutrition education program into the Film @ 6 after-school program – a STEM-focused program designed to assist …


Primary Care Providers' Provision Of Therapeutic Lifestyle Change Counseling For Patients With Cardiovascular Risk, Tristen Jackson Jan 2015

Primary Care Providers' Provision Of Therapeutic Lifestyle Change Counseling For Patients With Cardiovascular Risk, Tristen Jackson

Electronic Theses and Dissertations

Cardiovascular disease is important to the U.S. healthcare system, as it constitutes a high prevalence of deaths and costs the system billions each year. In lieu of this, research directed at preventative measures is important, especially those related to therapeutic lifestyle changes (TLC). TLC represents a host of healthy behaviors, such as physical activity and healthy nutrition, that have shown to provide benefits in both preventing and managing cardiovascular diseases such as hypertension, type 2 diabetes mellitus, and dyslipidemia. While public experts have advocated for physicians to recommend not only TLC for patients at cardiovascular risk but also to help …


Seed To Sale: Boundary Work In Mississippi Agriculture, Caroline Canarios Jan 2015

Seed To Sale: Boundary Work In Mississippi Agriculture, Caroline Canarios

Electronic Theses and Dissertations

From production to sale, farm operations thrive on the demanding work of farm labor. However, social research on agriculture does not give adequate attention to issues of labor and work. Through participant observation, interviews, and content analysis, I analyze work from multiple perspectives within Mississippi agriculture. I focus on individuals involved in produce farming in two communities located in Northwest and Southeast Mississippi. I apply the boundary work theoretical framework to my findings, which reveals the complexities of the agriculture sector in Mississippi and illuminates the ways in which individuals not only define themselves but the work they do and …


Association Of Kidney Stones With Chronic Disease Among Adults In The United States: Considerations By Race-Ethnicity, Lashaunta Marie Glover Jan 2015

Association Of Kidney Stones With Chronic Disease Among Adults In The United States: Considerations By Race-Ethnicity, Lashaunta Marie Glover

Electronic Theses and Dissertations

Background: little research has been conducted to describe the relationship between kidney stones and risk of cardiovascular disease and stroke in individuals of different race ethnicities. Purpose: the purpose of this study was to compare the prevalence of co-morbidities and to investigate whether there was a statistically significant association between kidney stone formers and increased odds of cardiovascular disease and stroke in race-ethnicity groups. Methods: data from the 2007-2012 cycles of the national health and nutrition examination survey (Nhanes) were used. Survey and biological data used included kidney stone cases, hypertension, obesity, diabetes, chronic kidney disease, cardiovascular disease and stroke. …


Effect Of Extrusion Pre-Treatment On Physical Properties And Sugar Recovery Of Cold Press And Solvent Extracted Canola, Camelina And Carinata Meal, Jasmeen Kaur Jan 2015

Effect Of Extrusion Pre-Treatment On Physical Properties And Sugar Recovery Of Cold Press And Solvent Extracted Canola, Camelina And Carinata Meal, Jasmeen Kaur

Electronic Theses and Dissertations

Canola/rapeseed meal (CM) ranks second behind soybeans in global production of protein from oil cakes and meals. Commercial CM has been investigated as a feed ingredient in diets of a number of fish species. Camelina (Camelina sativa) has been a potential oilseed crop. The fat extracted meal contains over 40% protein. Camelina yields an average of 420–640 L/ha, and the protein and fiber content in its meal byproduct is comparable to that of soybean meal. Brassica carinata possesses many positive agronomic traits, and it can grow well in hot, dry, and semiarid climates and seed oil from these species and …


Rapid Response Teams Versus Critical Care Outreach Teams: Unplanned Escalations In Care And Associated Outcomes, Valerie Danesh Jan 2015

Rapid Response Teams Versus Critical Care Outreach Teams: Unplanned Escalations In Care And Associated Outcomes, Valerie Danesh

Electronic Theses and Dissertations

The incidence of unplanned escalations during hospitalization is undocumented, but estimates may be as high as 1.2 million occurrences per year in the United States. Rapid Response Teams (RRT) were developed for the early recognition and treatment of deteriorating patients to deliver time-sensitive interventions, but evidence related to optimal activation criteria and structure is limited. The purpose of this study is to determine if an Early Warning Score-based Critical Care Outreach (CCO) model is related to the frequency of unplanned intra-hospital escalations in care compared to a RRT system based on staff nurse identification of vital sign derangements and physical …


Childhood Diet And Mobility At Medieval (1240s Ad) Solt-Tetelhegy, Hungary As Reconstructed From Stable Carbon, Nitrogen, And Oxygen Isotope Analysis, Ariana Gugora Jan 2015

Childhood Diet And Mobility At Medieval (1240s Ad) Solt-Tetelhegy, Hungary As Reconstructed From Stable Carbon, Nitrogen, And Oxygen Isotope Analysis, Ariana Gugora

Electronic Theses and Dissertations

Between 2005 and 2009, archaeologists excavated more than 100 skeletons from the medieval (1240s AD) Hungarian site of Solt-Tételhegy. Stable carbon and nitrogen isotope analyses were conducted on dental enamel and dentin from 24 individuals to examine their childhood diet. Although previous stable isotopic research has described the diet of medieval European peoples, this is the first such study on a medieval Hungarian population. The enamel ?13C values range from -14.4‰ to -8.6‰, with a mean of -11.1‰, while the dentin ?13C values range from -19.4‰ to -14.9‰, with an average of -17.4‰. These data indicate that C3 plants were …


"What We Eat Matters": Perspectives On Food And Health In The Mexican Im/Migrant Farmworker Communities In Indian River County, Florida, Hugo Puerto Jan 2015

"What We Eat Matters": Perspectives On Food And Health In The Mexican Im/Migrant Farmworker Communities In Indian River County, Florida, Hugo Puerto

Electronic Theses and Dissertations

The dramatic increase of type-2 diabetes within the Latino community is of great concern in the U.S., especially among Mexican im/migrant farmworkers. Anthropological scholarship shows that health issues within im/migrant groups in the U.S. are poorly understood from a sociocultural and local perspective. In Indian River County, Florida, farmworker leaders created a community garden in response to health problems in this community. This initiative was launched to educate families about the health and economic benefits of growing their own food. The Indian River County Health Department and the local leaders are working collaboratively to inform the community about the risks …


The Effect Of Training Volume And Intensity On Improvements In Muscular Strength And Size In Resistance-Trained Men, Gerald Mangine Jan 2015

The Effect Of Training Volume And Intensity On Improvements In Muscular Strength And Size In Resistance-Trained Men, Gerald Mangine

Electronic Theses and Dissertations

The magnitude of improvements in muscular strength and size are influenced by the volume and intensity of a resistance training program. While it is clearly advantageous for resistance-trained individuals to utilize programming specific to these goals, it not clear which is more important. Therefore the purpose of the present investigation was to determine the effect of focusing on training volume versus intensity on changes in muscle size and strength. Changes in muscular strength and size were examined in 29 resistance-trained men following 8 weeks of resistance training. Participants were randomly assigned to either a high volume (VOL, n = 14, …


Family Care Giver Knowledge, Patient Illness Characteristics, And Unplanned Hospital Admissions In Older Adults With Cancer, Patricia Geddie Jan 2015

Family Care Giver Knowledge, Patient Illness Characteristics, And Unplanned Hospital Admissions In Older Adults With Cancer, Patricia Geddie

Electronic Theses and Dissertations

Unplanned hospital admissions (UHA) in older adult populations are a recurring problem in older adults with cancer. Older adults comprise approximately 60% of cancer diagnoses and receive the majority of cancer treatment. However, little is known about why older adults under treatment for cancer experience a high number of unplanned hospital admissions. A review of the literature provided few study findings and a gap in the current knowledge was identified regarding the factors associated with unplanned hospital admissions in older adults under treatment for cancer. A conceptual framework based on the literature and this researcher's clinical experienced guided this study. …


The Effects Of Four Weeks Of High Intensity Interval Training And Β-Hydroxy-Β-Methylbutyric Free Acid On The Onset Of Neuromuscular Fatigue, Amelia Miramonti Jan 2015

The Effects Of Four Weeks Of High Intensity Interval Training And Β-Hydroxy-Β-Methylbutyric Free Acid On The Onset Of Neuromuscular Fatigue, Amelia Miramonti

Electronic Theses and Dissertations

This study investigated the effects of high intensity interval training (HIIT) and β-hydroxy-β-methylbutyric free acid (HMBFA) on the onset of neuromuscular fatigue in healthy young men and women. Thirty-seven subjects (22 men and 15 women; mean ± SD age = 22.8 ± 3.4yrs) completed an incremental cycle ergometer test (GXT) to exhaustion. During the GXT, electromyography (EMG) signals from the right vastus lateralis were recorded to determine the power output at the onset of neuromuscular fatigue (PWCFT), and peak wattage was used to assign individual training loads. After baseline testing (PRE), subjects were randomly assigned to one of three groups: …


Garden Soils: Reviewing The Viability Of Soil Phosphate Analyses In The Archaeological Identification Of Ancient Maya Kitchen Gardens, Cheryl Foster Jan 2015

Garden Soils: Reviewing The Viability Of Soil Phosphate Analyses In The Archaeological Identification Of Ancient Maya Kitchen Gardens, Cheryl Foster

Electronic Theses and Dissertations

The study of ancient Maya intensive, intra-site agricultural systems, such as kitchen gardens, has gained new interest in recent years as a valuable way of interpreting numerous aspects of the ancient Maya's daily life (e.g. subsistence and settlement patterns, population growth, diet and nutrition, gender roles). However, while contemporary Maya kitchen gardens can often be easily identified and studied by cultural anthropologists and archaeologists, ancient kitchen gardens are usually much harder to identify by traditional archaeological techniques because of their lack of architectural structures and other identifying features. To compensate for this limitation, various forms of chemical testing (primarily phosphate …


The Helping Professional Wellness Discrepancy Scale (Hpwds): Development And Validation, Ashley Blount Jan 2015

The Helping Professional Wellness Discrepancy Scale (Hpwds): Development And Validation, Ashley Blount

Electronic Theses and Dissertations

Wellness is an integral component of the helping professions (Myers & Sweeney, 2005; Witmer, 1985). Specifically, wellness is included in ethical codes, suggestions for practice, and codes of conduct throughout counseling, psychology, and social work fields (see American Counseling Association Code of Ethics, 2014; American Psychological Association Ethical Principles of Psychologists and Code of Conduct, 2010; National Association of Social Workers Code of Ethics, 1996). Even so, wellness in helping professionals is a difficult construct to measure. Thus, the purpose of the research investigation was to develop the Helping Professional Wellness Discrepancy Scale (HPWDS) and examine the psychometric features of …


Lightning Flowers, Nickalus Rupert Jan 2015

Lightning Flowers, Nickalus Rupert

Electronic Theses and Dissertations

Lightning Flowers traces the psychological collapse of Waylan Dranger, an East Texas construction worker / folk artist. Waylan suffers from hallucinatory encounters with Reeve, his missing brother. Reeve often blames Waylan for his disappearance and implied death. Waylan also worries that Sam, his live-in girlfriend, will leave him before he can resolve his own increasingly erratic behavior. Largely, Lightning Flowers is preoccupied with the consequences of nostalgic thinking. Among others, the novel grapples with the following questions: What defines contemporary notions of "brotherhood"? To what extent does one's survival necessitate self-delusion? How do social stigmas inform our experience of mental …


The Crypt People From The Cathedral Basilica Of Saints Stanislaus And Vladislaus, Vilnius, Lithuania: Reconstruction Of Life Histories Using Stable Isotope Analysis, Kaylee Schotten Jan 2015

The Crypt People From The Cathedral Basilica Of Saints Stanislaus And Vladislaus, Vilnius, Lithuania: Reconstruction Of Life Histories Using Stable Isotope Analysis, Kaylee Schotten

Electronic Theses and Dissertations

Stable isotope analyses of multiple tissue types have been used to reconstruct life histories of individuals from past populations. This thesis presents the life history reconstructions of a unique population recovered from a 16th to 18th century cathedral crypt located in Vilnius, Lithuania. The sample consists of 23 individuals (21 males, one possible female, and one juvenile). Stable carbon, nitrogen, and oxygen isotope analyses were performed on bone and dentin collagen, and on bone and enamel hydroxyapatite, resulting in eight isotope values per individual, providing both childhood and adult dietary and migration information. For bone collagen the average δ13C isotope …


Health Literacy, Health Disparities And Sources Of Health Information In Us Older Adults, Carolyn Cutilli Jan 2015

Health Literacy, Health Disparities And Sources Of Health Information In Us Older Adults, Carolyn Cutilli

Electronic Theses and Dissertations

This descriptive study is a secondary analysis of the National Assessment of Adult Literacy (NAAL) 2003, a large scale national assessment which included health literacy. It examined the relationships between health literacy and demographic/background characteristics in older adults (age 65 and over) related to health literacy and disparities, and sources of health information. Key findings include: 1) results support most relationships described in the conceptual model and literature associated with health literacy and disparities; 2) there are similarities and difference in the utilization of health information sources based on health literacy level; and 3) the results support established health literacy …


Prankster Questionaire., Matthew Landan 1972- Dec 2014

Prankster Questionaire., Matthew Landan 1972-

Electronic Theses and Dissertations

The creative thesis that I have written is a memoir. It is not complete in its detail or ambition but instead focuses on themes and topics of self-transformation, reinvention and the unintentional consequences of several nervous breakdowns and experiments with psychedelic substances. This thesis is just a beginning for a longer more drawn out memoir that will explore the themes above but also discuss family, one’s sense of self worth in the world and how patterns between fathers and sons repeat themselves. I hope to eventually publish this work in a commercial setting.


Modulation Of Host Polyubiquitination By The Ankb F-Box Protein Of Legionella Pneumophila., William M. Bruckert Dec 2014

Modulation Of Host Polyubiquitination By The Ankb F-Box Protein Of Legionella Pneumophila., William M. Bruckert

Electronic Theses and Dissertations

Legionella pneumophila is a facultative intracellular pathogen that infects a wide array of protozoan hosts and human alveolar macrophages. L. pneumophila is dependent on a functional Dot/Icm type IVB secretion system that translocates bacterial effector proteins into the host cell cytosol. L. pneumophila genomes encode more than 250 effector proteins, many of which inhibit host cellular processes to form a favorable niche termed the Legionella-containing vacuole (LCV). The eukaryotic-like Dot/Icm translocated effector AnkB contains two eukaryotic-like ankyrin protein-protein interacting domains, one eukaryotic-like F- box domain and an eukaryotic C-terminal CaaX motif. Immediately following attachment of extracellular bacteria, AnkB is translocated …


Evaluating The Effects Of Aroclor 1260 In Non-Alcoholic Fatty Liver Disease : The Role Of Xenobiotic Receptors., Banrida Wahlang Dec 2014

Evaluating The Effects Of Aroclor 1260 In Non-Alcoholic Fatty Liver Disease : The Role Of Xenobiotic Receptors., Banrida Wahlang

Electronic Theses and Dissertations

Polychlorinated biphenyls (PCBs) are persistent environmental toxicants, present in 100% of US adults and dose-dependently associated with nonalcoholic fatty liver disease (NAFLD) in epidemiologic studies. PCBs are predicted to interact with receptors previously implicated in xenobiotic/energy metabolism and NAFLD. These receptors include the aryl hydrocarbon receptor (AhR), pregnane xenobiotic receptor (PXR), constitutive androstane receptor (CAR), peroxisome proliferator-activated receptors (PPARs), liver-X-receptor and farnesoid-X-receptor. This study evaluated the hepatic effects of the PCB mixture, Aroclor 1260, whose composition mimics human bioaccumulation patterns, in a mouse model of diet-induced obesity. Male C57Bl/6J mice were fed a control or 42% high fat diet (HFD) …


The Role Of Stem Cells In Adipose Tissue Remodeling., Candice Reshay Holden 1988- Dec 2014

The Role Of Stem Cells In Adipose Tissue Remodeling., Candice Reshay Holden 1988-

Electronic Theses and Dissertations

The work presented in this dissertation outlines the role of stem cells in the remodeling of adipose tissue under conditions of nutrient excess. Obesity-induced variations in adipose tissue stem cell distribution were uncovered by analysis of the stromal vascular fraction isolated from mice fed a high fat diet for several weeks. Bone marrow cell transplantation was used to determine the derivation of progenitor cells found in adipose tissue; and supplementation of depleted progenitor cell populations achieved via direct cell transplantation, helped to determine the contribution of these progenitor cells to the remodeling process. The dissertation is presented in five chapters …