Digital Commons Network^™

Sexual Trauma, Health, And The Moderating Effect Of Psychological Flexibility And Inflexibility, Gabrielle A. Caselman

Electronic Theses and Dissertations

Sexual trauma is linked to adverse health outcomes (e.g., D’Andre et al., 2011). Given the negative sequelae of sexual trauma, exploration of factors that influence the relation between sexual trauma and health outcomes is crucial. Current literature suggests that psychological flexibility and inflexibility may be factors in promotion of individuals’ health or pathology (e.g., Gloster et al., 2017). The current study sought to explore the variability in psychological flexibility and inflexibility among participants and the potential moderating effects of psychological flexibility and inflexibility on the relation between sexual trauma and both mental and physical health outcomes.

Moderation analyses failed to …

Characteristics Of Refractivity And Sea State In The Marine Atmospheric Surface Layer And Their Influence On X-Band Propagation, Douglas Matthew Pastore

Electronic Theses and Dissertations

Predictions of environmental conditions within the marine atmospheric surface layer (MASL) are important to X-band radar system performance. Anomalous propagation occurs in conditions of non-standard atmospheric refractivity, driven by the virtually permanent presence of evaporation ducts (ED) in marine environments. Evaporation ducts are commonly characterized by the evaporation duct height (EDH), evaporation duct strength, and the gradients below the EDH, known as the evaporation duct curvature. Refractivity, and subsequent features, are estimated in the MASL primarily using four methods: in-situ measurements, numerical weather and surface layer modeling, boundary layer theory, and inversion methods.

The existing refractivity estimation techniques often assume …

Embodying An Afrofuturist Character On Stage: A Case Study In The Performance Of Sarah B. In Afromemory., Candace S. Spencer

Electronic Theses and Dissertations

This thesis explores Afrofuturism and positions Afrofuturist drama as a new, 21st -century genre of theatre. My thesis defines Afrofuturism and characteristics of Afrofuturist plays by Black women. My examination of Afrofuturist pieces and performance strategies is for Black female performers working in Afrofuturism. I show how Black female fiction writers contributed to Afrofuturism by examining two 20th -century plays by Black women that have Afrofuturist features but were written before the term was coined. I use Afromemory, a play produced by the University of Louisville Theatre Arts Department in Spring of 2022, as a case study of an …

Using Graphic Novels To Teach Economics Content To High School Students With Extensive Support Needs., Caroline Mae Fitchett

Electronic Theses and Dissertations

The purpose of social studies instruction in school is to facilitate the growth of competent citizens (National Council for the Social Studies [NCSS], 2013). Despite the recognized benefit of social studies instruction, emphasis on this subject has decreased over time, and has ultimately been termed a “dispensable subject” (Fitchett & Haefner, 2010). Social studies is an even more marginalized subject area for students with disabilities (Zakas et al., 2013). Expanding the research in this area is not only necessary to improving social studies academic content acquisition but is also likely to facilitate greater independence for students post-school – and by …

“Difference In/At The Center" A Transnational Approach For Mobilizing International Multilingual Graduate Writers' Writing Assets During Writing Instruction., Olalekan Adepoju

Electronic Theses and Dissertations

This research project presents an empirical exploration of how the writing assets possessed by international multilingual graduate writers impact the theory and pedagogical practices in writing studies, especially regarding the approaches to teaching writing. Extant scholarship in writing studies, especially on second language research/teaching, translingual writing practices, and asset-based writing pedagogy has engaged issues of difference in language, race, culture, as well as funds of knowledge, highlighting the impacts of these differences on the academic success of non-native English speakers in US schools and colleges. My dissertation builds on these trends and highlights the narratives, perceptions, and experiences of international …

From Androgyny To Binary And Back: A Qualitative Analysis Of Nonbinary Tiktoks., Savannah Hatton

Electronic Theses and Dissertations

This study explores how nonbinary individuals represent and express their gender on TikTok. Given the limited amount of research that has been done on nonbinary gender expression in online spaces, this study uses TikTok to observe the ways that nonbinary individuals perform gender. Additionally, given the relative newness of TikTok, this study serves to inform growing research on identity formation through social media. It used a sample of fifty TikToks by nonbinary creators to perform a content analysis. The findings reveal significant variation in how nonbinary individuals "do gender" on the platform, with some individuals identifying closely with binary labels, …

Cannabidiol Tweet Miner: A Framework For Identifying Misinformation In Cbd Tweets., Jason Turner

Electronic Theses and Dissertations

As regulations surrounding cannabis continue to develop, the demand for cannabis-based products is on the rise. Despite not producing the psychoactive effects commonly associated with THC, products containing cannabidiol (CBD) have gained immense popularity in recent years as a potential treatment option for a range of conditions, particularly those associated with pain or sleep disorders. However, due to current federal policies, these products have yet to undergo comprehensive safety and efficacy testing. Fortunately, utilizing advanced natural language processing (NLP) techniques, data harvested from social networks have been employed to investigate various social trends within healthcare, such as disease tracking and …

Inhibition Of Ras As A Novel Therapeutic Approach In Luminal B Breast Cancer., Raphael Ngozichi Jigo

Electronic Theses and Dissertations

Historically, the RAS oncoprotein has not been implicated in breast cancer due to less than 1% of breast cancer cases bearing oncogenic RAS mutations. Recently, however, it has been reported that greater than 60% of Luminal B breast cancer cases have a decreased expression of negative RAS regulators RASAL2 and DAB2IP. Thus, in many Luminal B breast cancers, RAS remains in a constitutively active state without mutation, in turn driving oncogenesis. To date, there are no FDA-approved direct inhibitors of wild type RAS. We have developed a direct RAS inhibitor that acts on wild type RAS using in silico drug …

Understanding The Role Of Sabp2-Interacting Protein (Sip) 428: An Nad+-Dependent Deacetylase Enzyme In Abiotic Stress Signaling Of Nicotiana Tabacum, Mariam Onabanjo

Electronic Theses and Dissertations

Abiotic stresses are constantly rising and pose a very high risk to global agricultural productivity and food security. Some plants have evolved several innate pathways for defense against these stresses. Hence, understanding stress signaling pathways can help develop crop plants with higher stress tolerance. The salicylic acid-mediated signaling pathway is important in plants experiencing biotic and abiotic stresses. In previous studies, SABP2-Interacting Protein (SIP-428) has been shown to be a negative regular of plant growth under abiotic stress. This study aimed to investigate the roles of SIP-428 in the ROS signaling of tobacco plants. We investigated transgenic RNAi-silenced lines of …

“Just As Scared As I Am”: Daughters’ Perspectives Of The Impact Of The Overturning Of Roe V. Wade On Mother-Daughter Reproductive Conversations, Casadie Smith

Electronic Theses and Dissertations

Existing literature has identified mothers as the primary reproductive educators of their daughters and has determined mother-daughter conversations about reproduction to be an indicator of daughters’ sexual and reproductive behaviors. The overturning of Roe v. Wade on June 24, 2022, had an immediate impact on the reproductive lives of many people, including daughters. Through one-on-one interviews with 10 daughters, this qualitative study identifies three changes in mother-daughter reproductive conversations that were influenced by the overturning of Roe v. Wade: (a) The initiation of conversations, (b) the topics of conversations, and (c) the tone of these conversations. The results of this …

Use Of Transposon Screening For Salicylic Acid-Assisted Desiccation Killing In Salmonella, Shannon D. Elliott

Electronic Theses and Dissertations

Salmonella enterica serovar Typhimurium is one of the most prevalent food-borne pathogens, affecting millions around the world every year, making it a threat to global health. Salmonella possesses the ability to survive the normally lethal condition of desiccation, however, discovery of the genes and mechanisms behind this phenomenon are still ongoing. Using a transposon mutagenesis approach to construct a broad transposon library, this study aimed to uncover genes that may be contributing to changes in Salmonella’s survivability under desiccation, particularly when exposed to the antimicrobial molecule salicylic acid. Building on previous findings showing salicylic acid can alter cell viability …

Food Insecurity And Residential Segregation Among Adults In The United States: The National Health And Nutrition Examination Survey 2017- March 2020 Pre-Pandemic Data., Chandre' L. Chaney

Electronic Theses and Dissertations

Food insecurity is when a household has insufficient food supply due to limited economic resources. It is a public health issue that continues to persist. The health, social, and economic impact affects millions of people nationwide. Residential segregation is a primary cause of inequities and health disparities. It shapes the differences in socio-economic conditions between Blacks and Whites living in the U.S. This country is segregated across racial lines in many of our most populated metropolitan cities. Americans worship in different churches, learn in disparate schools, and live in separate neighborhoods. Residential segregation has consequences that impact the economy, professional …

Mapping The Binding Site Within Integrin D2 For Carboxyethylpyrrole (Cep)-Modified Proteins, Afia Prema

Electronic Theses and Dissertations

Neutrophils and macrophages accumulate at sites of inflammation and cause chronic inflammation leading to various diseases. Therefore, to better understand chronic disease pathways it is important to investigate the properties of macrophage accumulation in inflamed tissues. The I-domain of the macrophage receptor integrin a_Db₂ plays a vital role in macrophage retention by binding to CEP (carboxyethyl pyrrole), a ligand available at inflammatory sites. This thesis mainly focuses on evaluating the binding site within integrin a_Db₂ that binds carboxyethyl pyrrole (CEP)-modified proteins. So, a recombinant plasmid construct containing the integrin I-domain was developed. Seven non-conserved …

Strong As A Mother: The Resilience Of Women Who Have Previously Experienced Infertility, Madison Hinkle

Electronic Theses and Dissertations

Infertility impacts numerous individuals during their reproductive journey. Yet, there is little research and information available that examines if having a history of infertility goes on to have further implications after an individual conceives and gives birth. Thus, the current study aimed to examine if infertility impacts the postpartum period, and if there were any particular risk or resiliency factors that contributed to this relationship. In this study, women aged 18 to 50, who had given birth within the last 12 months, participated in an online survey that assessed a variety of physical and mental health constructs. Overall, results largely …

Tennessee Promise And Two-Year Community College Retention And Graduation In Rural Appalachia, Tammy Dycus

Electronic Theses and Dissertations

The purpose of this quantitative, non-experimental study was to explore the relationship between the implementation of the Tennessee Promise scholarship program and the two-year Tennessee community college retention rates and graduation rates of first-time, full-time Tennessee students from rural Appalachian counties. Results from this study may help higher education stake-holders better understand the features of Tennessee Promise that are influencing an increase in community college retention and graduation rates for Tennessee students from rural Appalachian counties. The theoretical framework that guided this research was the social capital framework. Data including use of Tennessee Promise, county of origin, retention, and graduation …

Microsporidian Spores And The Integrin Binding Loop Of The Madam Protein Are Important For Integrin Signaling And Attachment To Host Cells, Cindy L. Barrett

Electronic Theses and Dissertations

Microsporidia are a distant fungal pathogen that have severe clinical consequences for the immunocompromised. Previous work identified a microsporidian pathogen protein termed Microsporidian ADAM or MADAM. This protein has close sequence homology to other ADAM proteins (A Disintegrin and Metalloproteinase) in two microsporidian species, Encephalitozoon intestinalis and E. cuniculi. ADAM proteins have a wide range of functions, including binding to integrins and host signaling. It is known that many pathogens manipulate integrins to invade host cells, and it is predicted that microsporidia are also exploiting this host target. Previous work with the MADAM protein demonstrated that this protein has a …

Exploring The Experiences Of Underrepresented Students Pursuing Health-Related Graduate Or Professional Programs, Alison Williams

Electronic Theses and Dissertations

For many years graduate and professional education programs for the health professions have sought to increase the diversity of their student body to include students from a wider variety of backgrounds. Increasing the diversity of healthcare providers is an essential component of addressing inequities in healthcare. However, despite initiatives to increase racial and ethnic diversity in the health professions, these professions remain largely White and female. Previous researchers have sought to identify the reasons that racial and ethnic minorities are underrepresented in healthcare, and the barriers to persistence and success. Little research exists explaining why men are underrepresented in the …

Investigation Of The Protein Components In A Periplasmic Mechanism Regulating Bacterial Morphology, Alexandra Pulliam

Electronic Theses and Dissertations

Salmonella is a leading bacterial cause of foodborne illness worldwide. During a previous study investigating the enzymes responsible for regulating cyclic-di-GMP concentrations, a mutant in the cyclic-di-GMP-specific phosphodiesterase STM3615 was identified that displayed a phenotype characterized by decreased survival on agar plates and a shorter bacterium length. I was able to determine that the periplasmic domain of STM3615 was responsible for this phenotype, not the enzymatic phosphodiesterase domain. Based upon a bioinformatic analysis of the protein, I then hypothesized that the periplasmic domain of STM3615 was interacting with a periplasmic protein to give rise to this phenotype. To identify this …

Extraction, Purification, And Characterization Of Potential Bioactive Compounds Produced By Janthinobacterium Lividum Tajx1901, Andy Elorm Agbakpo

Electronic Theses and Dissertations

Underexplored environments such as soil samples continue to be an untapped source of bacterial strains with great potential to produce secondary metabolites for medicinal applications. As a result, these microorganisms represent a broad and yet unknown reservoir of new strains capable of producing these novel compounds. The current research primarily seeks to perform the isolation, purification, and characterization of secondary metabolites from a soil bacterium (Janthinobacterium lividum TAJX1901). The isolated soil bacterium was successfully cultured on rich media agar plates, followed by extraction using methanol and chloroform. The purification methods utilized include flash column chromatography, preparative thin-layer chromatography, and …

Isolation And Structural Determination Of Bioactive Metabolites From The Soil Bacterium, Arthrobacter Sp. Tajx1902, Amonah Arije

Electronic Theses and Dissertations

As antimicrobial resistance persistently disrupts the treatment of microbial infection, natural product chemistry has played a significant role in identifying novel drugs with novel modes of action critical to getting ahead of resistance. The primary goal of this project is to extract and identify potential novel antimicrobial natural products produced by Arthrobacter sp. Although underexplored, Arthrobacter sps. have been known to produce bioactive compounds with versatility; one such is a depsipeptide with quorum-sensing inhibitory activity.¹ In this research, an Arthrobacter sp. TAJX1902, isolated from a soil sample, showed inhibitory activity against a filamentous indicator bacterium and a violacein-producing Janthinobacterium …

When Data Matter: Evaluating Data Prioritization For Department-Level Decision-Making In Higher Education, Cindy Cragg

Electronic Theses and Dissertations

The purpose of this program evaluation was to better understand the department-level leadership’s decision-making process and, within that process, when data are used to inform decisions related to the school’s mission to deliver an exceptional student experience. The evaluation took place at a school of professional and continuing education at a private institution in the Mountain West region. This evaluation’s central focus was to learn what the assumptions were that informed how the leadership prioritized data related to the student experience in their decision-making process. Secondarily, the evaluation explored what organizational conditions would be necessary for unused student-generated qualitative data …

Investing In Your Employees: Understanding The Impact Organizational Commitment Has On Staff Retention, Vanessa Lynne Mcwhirt

Electronic Theses and Dissertations

High employee turnover in higher education has been an issue for decades, and successfully integrating newly hired staff (NHS) into their new job and the organization can be challenging for human resources and leadership. New employee orientation and onboarding programs can assist NHS. The author of this paper conducted a Utilization-Focused evaluation of the Thriving at DU program at the University of Denver (DU) to improve the program. The study examined the perceptions of how 12 student and academic affairs professionals made meaning of organizational commitment in the workplace throughout their onboarding experience.

The major findings of this evaluation aligned …

Liberation And Inclusion Through The Voices Of Trans Youth: A Phenomenological Approach, Klaudia Neufeld

Electronic Theses and Dissertations

The primary aim of this phenomenological study is to elevate trans youth voice to understand the essence of their individual and shared lived experiences within school systems designed for them to be silenced, excluded, and erased. In alignment with Eve Tuck’s desire-based research, this study is designed to counter deficit narratives of trans youth. Participants include six racially and ethnically diverse trans youth, ages 13−17 in the U.S. state of Colorado. Analyses revealed four themes: a gender-identity transition journey; navigating geography; safety and the impact of school culture; creating belonging through a coalition of community and friendship; and youth lessons …

Providers’ Effective Approach: Reducing Resistance To Insulin Treatment In Type 2 Diabetic Patients With Hyperglycemia, Eden A. Tsegay

Electronic Theses and Dissertations

Resistance to insulin therapy is primarily due to emotional and intellectual perceptions among patients with type 2 diabetes (T2D) new to insulin therapy. Providers’ effective approach to diabetes education equips patients with knowledge, which can reduce resistance to insulin therapy. This project included patients with T2D between the ages of 18 to 70 whose glycated hemoglobin (HgbA1c) was ≥ 8.5% taking two or more oral antidiabetic agents and not on insulin therapy. Data were collected using the Insulin Treatment Appraisal Scale (ITAS), a 20-item instrument that contains 16 negative and four positive statements that appraise an individual’s perception of insulin …

How Interactions With An Academic Advisor Influence The Self-Efficacy Of Online And Distance Education Students, Tonya Renae Fulk

Electronic Theses and Dissertations

Institutions of higher education are experiencing an increasing number of students enrolling in online or distance education courses. The majority of these students are adult learners. The increase in enrollment is beneficial to institutions of higher education, but it is overshadowed by the low degree completion rate for online and distance education learners. Academic advisors play a crucial role in guiding students to degree completion. While there has been research on the potential contributing factors in online and distance education student retention, the research has been lacking in how communications with academic advisors may influence students’ levels of self-efficacy. The …

Effects Of Parental Deployment On Military-Connected High School Students And Strategies For Academic Success, Sean T. Lucas

Electronic Theses and Dissertations

Abstract The problem investigated in this study was unknown opportunities that exist for educators to meet the academic needs of students who are affected by combat parental deployment and how this challenge of combat deployment disrupts the family’s dynamic, thus challenging their children academically. The Air Force, Army, Navy, Marines, and Coast Guard made up about 1% of the total United States population in 2015. Most of these people were married, 42% had children, and 54% of their children were in kindergarten to 12th grade. The Department of Defense school system is comprised of 166 accredited schools across 11 foreign …

The Impact Of The Digital Divide On Rural Community College Students, Martin Ray Sheppard

Electronic Theses and Dissertations

Abstract

This qualitative case study investigated the perceived impact of the digital divide on rural U.S. community college students. An online survey was conducted of adult community college students at a rural community college. In addition, volunteer faculty at the same institution were interviewed through Zoom. The purpose of the student surveys and faculty interviews was to determine the impact of the digital divide on rural community college students and the ways in which these students seek to overcome the divide. This study used a theoretical framework that combined aspects of the situational theory of problem solving (STOPS) with the …

Why Democracies And Autocracies Go To War: Comparing The Cases Of Iraq And Ukraine, Ketevan Chincharadze

Electronic Theses and Dissertations

History shows that both democratic and nondemocratic countries wage wars to advance their strategic interests. This study has comparatively analyzed two conflicts – the 2003-2011 U.S. invasion of Iraq and Russia’s ongoing war in Ukraine – to identify the trends that motivate both democratic and autocratic leaders to behave similarly by launching an invasion. The interpretive research of various memoirs, books, interviews, academic articles, news reports, and speeches, has uncovered that personal biases, particularly confirmation biases, play a significant role in motivating leaders to start a war. Leaders’ confirmation biases are often shaped by three prominent factors – historical memory, …

Something Wicked: Witches And Rhetorics Of Resistance, K. Scarlett Harrington

Electronic Theses and Dissertations

This project joins other academic conversations regarding the dynamics of power, modernity, witchcraft, and magic within the contexts of Western hegemony. Occasioned by kairotic cultural events and the reinforcement of ideologies like those found in the Dobbs decision, QAnon conspiracy, and rise of Christian Nationalism, this project contends that evaluating the potential political power residing in witchery is necessary in understanding some of the nuances of hegemonic control and resistance to oppressive authority. Predominantly following rhetorical evaluations of magic found in the works of Gunn and Covino, I maintain a non-universal methodological practice that works to understand the various instrumentality …

Vegetal Being: Dreamwork, Ritual, And Performance In Han Kang’S The Vegetarian, Briana Hanratty

Electronic Theses and Dissertations

In this thesis, I am writing towards an ecofeminist informed reading of the English version of The Vegetarian by Han Kang, translated by Deborah Smith. My aim is to display how, like an ecosystem of complex interdependency, it is impossible to separate body from theory from text from ecological context. To engage with this form of ecofeminism, I center an autotheoretical methodology with voices from ritual theory and performance theory in order to examine how Yeong-hye, the titular vegetarian of Han Kang’s novel, operates as a narrative-level metaphor for the desire for erotic ecology as a mode of ecological and …