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Evaluation Of The Antecedents Of Cultural Competence, Mary Harper

Electronic Theses and Dissertations

Purpose: The threefold purpose of this research is to identify the essential antecedents of cultural competence as identified by international nurse researchers, to compare the content of the extant cultural competence instruments to these antecedents and to potentially identify gaps in their conceptualization. A secondary aim of this research is to initiate validation of Harper's model of ethical multiculturalism. Conceptual Basis: The model of ethical multiculturalism depicts the attributes of ethical multiculturalism as the fulcrum of a balance between two ethical philosophies of fundamentalism and relativism. The attributes of moral reasoning, beneficence/nonmaleficence, respect for persons and communities, and cultural competence …

Fine Scale Patterns In Microbial Extracellular Enzyme Activity During Leaf-Litter Decomposition In A Stream And Its Floodplain / By Kurt Smart, Kurt Smart

Electronic Theses and Dissertations

No abstract provided.

A Numerical Analysis Approach For Estimating The Minimum Traveling Wave Speed For An Autocatalytic Reaction, Erika Blanken

Electronic Theses and Dissertations

This thesis studies the traveling wavefront created by the autocatalytic cubic chemical reaction A + 2B → 3B involving two chemical species A and B, where A is the reactant and B is the auto-catalyst. The diffusion coefficients for A and B are given by DA and DB. These coefficients differ as a result of the chemical species having different size and/or weight. Theoretical results show there exist bounds, v* and v*, depending on DB/DA, where for speeds v ≥ v*, a traveling wave solution exists, while for speeds v < v*, a solution does not exist. Moreover, if DB ≤ DA, and v* and v* are similar to one another and in the order of DB/DA when it is small. On the other hand, when DA ≤ DB there exists a minimum speed vmin, such that there is a traveling wave solution if the speed v > vmin. The determination of vmin is very important in determining …

Health-Care Seeking Behaviors Of Puerto Ricans With Diabetes Mellitus Who Live In South Florida: An Exploratory Study, Laura Gonzalez

Electronic Theses and Dissertations

Latinos are the fastest growing minority population in the United States (U.S.) and have the worst access to health care of any ethnic group. The chronic disease of diabetes is twice as common in adult Latinos as in non-Latino whites, and the risk of death related to diabetes is twofold. Reasons for this disparity have yet to be clearly identified. This study had two purposes: 1) to explore cultural beliefs regarding health-care seeking behaviors in Puerto Ricans with diabetes who live in South Florida; and 2) to examine Puerto Ricans' perceptions about their health-care providers. The cultural phenomena of interest …

Haitian American Mothers' Health And Dietary Beliefs Concerning Their Infants, Daniel Schooler

Electronic Theses and Dissertations

Studies on the effects of immigration are becoming more important as the number of immigrants into the United States continues to grow. This study was implemented in order to discover the infant feeding practices and beliefs of Haitians living in Central Florida. A food frequency card sort and interview were conducted with thirty-four Haitian mothers. Mothers were asked to identify which foods they fed their children. Foods pictured on the cards included a majority of Haitian staple foods, some of which are primary to the American diet as well. Low food feeding frequencies were generally attributed to lack of access …

Globalization And Social Work Education : An Initial International Inquiry., Elaine Rushmore Wright

Electronic Theses and Dissertations

With an increasing awareness of a global-local reality, social work research and theorizing on globalization is limited but growing. From a multinational perspective, the purpose of this dissertation was to contribute to the emerging professional discourse through (a) an examination of definitions and dimensions of globalization and (b) and an exploration of the impact of globalization on social work education. Perspectives on globalization were collected on a newly designed and translated survey from 46 social work educators from schools and social work in China, Germany, Russia, and the United States of America. Descriptive analysis and the coding of themes were …

T-Cell Dysfunction By Hcv Core Protein Involves Pd-1/Pd-L1 Signaling., Billy Ellis King

Electronic Theses and Dissertations

In 1989 the hepatitis C virus was identified as a significant cause of post-transfusion hepatitis. Nearly two decades later there is still no vaccine, inadequate treatment options, and limited understanding of how the virus establishes chronicity in the majority of the people it infects. Recent reports suggest that the interaction of a negative co-stimulatory pathway mediated by PD-1 and PDL-1 is associated with persistent viral infection. The role, if any, that PD-1/PDL-1 has in HCV infection is unknown. In this study we report that PD-1 is upregulated in T-cells from persons with chronic HCV infection when compared to healthy donors. …

Examination Of Microsporidia Spore Adherence And Host Cell Infection In Vitro., Timothy Robert Southern

Electronic Theses and Dissertations

Microsporidia are obligate intracellular pathogens that cause severe disease in immunocompromised humans. While albendazole is the treatment of choice, no therapy exists that effectively treats all forms or causes of human microsporidiosis. Recent studies show that the microsporidian Encephalitozoon intestinalis binds glycosaminoglycans (GAGs) associated with the host cell surface, and that the divalent cations manganese (Mn²⁺) and magnesium (Mg²⁺) augment spore adherence to host cells by activating a constituent on the spore surface. These studies also illustrate a direct relationship between spore adherence and host cell infection; inhibition of spore adherence leads to reduced host cell …

Studies On A 50s Ribosomal Precursor Particle As A Substrate For Erm E Methyltransferase Enzyme In Staphylococcus Aureus ., Indira Pokkunuri

Electronic Theses and Dissertations

Erythromycin is a macrolide antibiotic that inhibits not only mRNA translation but also 50S ribosomal subunit assembly in bacterial cells. An important mechanism of erythromycin resistance is the methylation of 23S rRNA by erm methyl transferase enzymes. We are interested in investigating the true substrate for methylation because it is known from our work and the work of others that fully assembled 50S subunits are not substrates for methylation. We have published a model for 50S ribosomal subunit formation where, the precursor particle that accumulates in erythromycin treated cells is a target for methyl transferase activity. Current studies are aimed …

Social Pathogenic Sources Of Poor Community Health, Hayden Smith

Electronic Theses and Dissertations

The United States currently provides a health care system that is neither efficient nor equitable. Despite outspending the world on health care, over three-fourths of developed countries produce better health outcomes (Auerbach et al., 2000). Simultaneously, the "Ecological School of Thought" has documented the large impact that social, economic, and environmental circumstances play in health outcomes. Unfortunately, these 'ecological" studies are frequently conducted without theoretical justification, and rely solely on a cross-sectional research design and a myriad of unrelated variables. This study represents an important step towards the development of a true theory of "ecology". More specifically, we argue that …

Biostability In Drinking Water Distribution Systems In A Changing Water Quality Environment Using Corrosion Inhibitors, Bingjie Zhao

Electronic Theses and Dissertations

In this study, the bacterial growth dynamics of 14 pilot drinking water distribution systems were studied in order to observe water quality changes due to corrosion inhibitor addition. Empirical models were developed to quantity the effect of inhibitor type and dose on bacterial growth (biofilm and bulk water). Water and pipe coupon samples were taken and examined during the experiments. The coupons were exposed to drinking water at approximately 20°C for at least 5 weeks to allow the formation of a measurable quasi- steady-state biofilm. Bulk water samples were taken every week. In this study, two simple but practical empirical …

Anti-Infective Agents From The Terrestrial Plants Zanthoxylum Monophyllum (Lam.) P. Wilson And Sorocea Muriculata Miq. Against Pathogenic Fungi, Methicillin-Resistant Staphylococcus Aureus And Plasmodium Falciparum, Raquel Rodr├¡Guez Guzm├Ín

Electronic Theses and Dissertations

No abstract provided.

Positioning For Acceptance: How Women With Hiv Infection Manage Their Relationships, Mary Kozy

Electronic Theses and Dissertations

Even though the number of women with Human Immunodeficiency Virus (HIV) grows annually, medical treatment has rendered this illness a chronic but manageable disease. Nurses must expand their knowledge beyond issues of survival and end of life care and focus on ways to maintain health and well being in this population. The works of Miller (1986) and Gilligan (1993) underscore the significance of relationships in the emotional well being of women. Issues of stigma, sexual transmission and ill health render HIV infection a threat to social relationships. Published literature exists that explores aspects of relationship such as social support, motherhood …

The Politics Of Medical Syncretism In The Ghanaian National Healthcare System, Mark Morrison

Electronic Theses and Dissertations

Efforts to create public policy integrating traditional/indigenous medical practices and practitioners into national healthcare strategies are currently being pursued in a variety of nations in the Africa region. The purpose of this research is to present a historical case study of the social and political factors associated with the passage of the Traditional Medicine Practice Act of 2000 in the West African nation of Ghana. Research methodology included conducting a thorough examination of available archival and secondary data as well as an abbreviated interview series (N=5). Research findings suggest that significant factors associated with Ghanaian medical revivalism were the role …

Evaluation Of An Education Intervention For The Staff On The Head Of The Bed Elevation In The Pediatric Intensive Care Unit, Randall Johnson

Electronic Theses and Dissertations

Elevating the head of bed (HOB) reduces risks for aspiration and ventilator associated pneumonia (VAP) in the adult population. Educational interventions have resulted in improvements in achieving a target HOB elevation of 30° in adults. Limited research has addressed this intervention in the pediatric intensive care unit (PICU). The aim of this study was to determine if an educational intervention for the PICU staff would result in improvement in the HOB elevation in the PICU. Four research questions were studied: 1) What is the common practice related to the elevation of the HOB in the PICU? 2) Is there a …

A Mathematical Study Of Two Retroviruses, Hiv And Htlv-I, Dana Ali Baxley

Electronic Theses and Dissertations

In this thesis, we examine epidemiological models of two different retroviruses, which infect the human body. The two viruses under study are HIV or the human immunodefiency virus and HTLV-I, which is the human T lymphotropic virus type I. A retrovirus is a virus, which injects its RNA into the host, rather than it's DNA. We will study each of the different mathematical models for each of the viruses separately. Then we use MATLAB-SIMULINK to analyze the models by studying the reproductive numbers in each case and the disease progression by examining the graphs. In Chapter 1, we mention basic …

Dectin-1 Expression Is Altered By Fungal Infection, Polymicrobial Sepsis, And Glucan Administration., Tammy Regena Ozment-Skelton

Electronic Theses and Dissertations

Glucans are fungal cell wall PAMPs that promote survival in polymicrobial and candidal sepsis. Dectin-1 is the primary PRR for glucans. The goals of the present study were to characterize 1) the effects of fungal infection on Dectin-1; 2) the effects of polymicrobial sepsis in the presence and absence of glucan on Dectin-1; 3) the effects of systemic administration of glucans on Dectin-1; and 4) the intracellular trafficking of glucans. Mice were either systemically infected with Candida albicans, or made septic by CLP with and without glucan phosphate (GP) injection, or injected with GP. Flow cytometry was performed to …

Latex Of Sciadopitys Verticillata (Thunb.) Siebold And Zuccarini: Antibiotic Properties, Phytochemistry, And Inhibition Of Adventitious Rooting Of Stem Cuttings., David Ira Yates

Electronic Theses and Dissertations

Sciadopitys verticillata was subjected to three propagation treatments designed to inhibit coagulation of its latex-like sap at the cut ends of the stem cuttings. Twenty-four hour soaking in water prior to rooting hormone application significantly enhanced production of adventitious roots. Old wood stem cuttings from shade-grown trees rooted at higher proportions than stem cuttings collected from sun-grown trees. Height, age, and place of origin of the source trees were not important factors in successful rooting. Antibacterial activity against some human pathogens and soil bacterial species was detected in latex application trials but the antibiotic activity was not related to the …

Connecting Health Concepts And Health Behavior : The Construction Of Health Identity., Valerie French

Electronic Theses and Dissertations

This thesis is an historical, theoretical and empirical examination of women's health concepts and health behavior in contemporary consumer-oriented American society. It begins with an historical overview of social health movements to illustrate how health concepts are shaped by cultural, social, political, and moral beliefs and practices. It then traces the socio-cultural construction of "health" to understand how this concept is shaped by various social and individual factors. The qualitative methodology of grounded theory was used to examine empirically how a sample of women defines "health" and what behaviors they engage in related to "health." Non-random convenience sampling was employed …

Conjugative Transfer Pathways Of High-Level Mupirocin Resistance And Conjugative Transfer Genes In Staphylococcus., Danielle Barnard

Electronic Theses and Dissertations

To combat widespread infections caused by Staphylococcus aureus, mupirocin was introduced at the Veterans Affairs Medical Center, Mountain Home, Tennessee. Soon after introduction, high-level mupirocin-resistance emerged. The rapid emergence was hypothesized to be due to conjugative transfer of the mupA resistance gene from S. epidermidis to S. aureus. Results have shown that transfer of high-level mupirocin-resistance from S. aureus donors commonly occurs. However, transfer from naturally-occurring S. epidermidis donors was not attainable. Staphylococcus epidermidis transconjugants, however, were capable of serving as donors. Further examination of non-transmissibility included PCR analysis of conjugative transfer genes (tra genes) in capable …

The Cost Of Mupirocin Resistance In Staphylococcus., Susan D. Reynolds

Electronic Theses and Dissertations

Control of antibiotic resistance in bacteria is based on the concept that resistance incurs a fitness cost in non-selective conditions. Fitness costs were assessed for low- and high-level mupirocin resistance in locally-derived Staphylococcus aureus and S. epidermidis. Costs of resistance were assessed in pure cultures by comparing growth curve characteristics and in mixed culture as the proportion of resistant cells surviving. Costs were not present in comparisons of growth rates among groups of naturally-occurring isolates from the different resistance categories. However, in S. aureus, growth rates within resistance categories differed by approximately 30 – 90%. Among near-isogenic pairs …

Arf : An Automated Real-Time Fuzzy Logic Threat Evaluation System., Jeremy D. Gray

Electronic Theses and Dissertations

Intrusion Detection has emerged as a powerful component of network security systems. A wide range of hardware and software components exist to meet most basic security needs on all platforms. These systems log system usage that could be considered as a breach of security in many networks. However, signature based intrusion detection systems have one catastrophic downfall, in that the number of alerts being logged can quickly outgrow the amount of resources necessary to investigate this anomalous behavior. This thesis explores the use of a fuzzy logic based analysis engine that gives an overall threat level of an intrusion detection …

Expression Of Heterologous Proteins In Transgenic Tobacco Chloroplasts To Produce A Biopharmaceutical And Biopolymer, Andrew Leon Devine

Electronic Theses and Dissertations

The chloroplast has been demonstrated to be an ideal compartment to accumulate certain proteins or their biosynthetic products that would be harmful if they were accumulated in the cytoplasm. Hyper-expression of foreign proteins in chloroplast transgenics has accumulated up to 46% total soluble protein, this is possible due to the ~100 chloroplast genomes per chloroplast and ~100 chloroplasts per cell which can therefore, contain up to 10,000 copies of the transgene. Maternal gene inheritance of plastids in most crop plants results in natural gene containment. Chloroplast transformation also eliminates positional effects that are frequently observed with nuclear transformation and no …

The Effect Of Job Strain In The Hospital Environment: Applying Orem's Theory Of Self Care, Diane Andrews

Electronic Theses and Dissertations

The purpose of this research was to evaluate the causal relationships between job strain, the practice environment and the use of coping skills in order to assist in the prediction of nurses who are at risk for voluntary turnover. It was conducted at the level of the individual nurse employee in order to better understand the health consequences associated with job strain, the factors in the professional practice environment which may contribute to the propensity to leave and the influence of coping behaviors in response to workplace stressors. It was undertaken with the intention of identifying intervention strategies which will …

On Modeling Hiv Infection Of Cd4+ T Cells, Amy Comerford

Electronic Theses and Dissertations

We examine an early model for the interaction of HIV with CD4+ T cells in vivo and define possible parameters and effects of said parameters on the model. We then examine a newer, more simplified model for the interaction of HIV with CD4+ T cells that also considers four populations: uninfected T cells, latently infected T cells, actively infected T cells, and free virus. The stability of both the disease free steady state and the endemically infected steady state are examined utilizing standard methods and the Routh-Hurwitz criteria. We show that if N, the number of infectious virions produced per …

Exploring The Relationship Between Intimate Partner Violence And Hiv Risk Propensity In African American Women, Lauren Lois Josephs

Electronic Theses and Dissertations

This study explored the relationship between Intimate Partner Violence and HIV Risk-Propensity in African-American women. Current literature on HIV reveals that one of the groups most seriously impacted by the continued scourge of HIV is African-American heterosexual women. An anonymous questionnaire was completed by a community based sample of 200 African American women with a varied history of intimate partner violence to (1) explore whether a relationship exists between Intimate Partner Violence and sexual coercion in African-American women (2) determine whether a relationship exists between sexual coercion and HIV Risk in African-American women (3) determine if the frequency of intimate …

Health Attitudes, Knowledge And Literacy Of Primary Caregivers With Elementary School Children, Susan Stuib

Electronic Theses and Dissertations

Previous research has indicated that physical activity and healthy eating in elementary school children are the exception rather than the norm. Increased attention to the rising rates of childhood obesity, coupled with the recognition that changes in the school environment are critical to reducing this trend, has intensified the need to adopt better practices in school nutrition, physical activity and physical education. Apart from being physically active, children need to learn fundamental motor skills and develop health related physical fitness (cardiovascular endurance, muscular strength and endurance, flexibility, and body composition). Primary caregivers play an important part in developing and teaching …

The Lived Experience Of Lebanese Oncology Patients Receiving Palliative Care, Myrna Doumit

Electronic Theses and Dissertations

The purpose of this study was to uncover the lived experience of Lebanese oncology patients receiving palliative care. The study design was based on the Utrecht School of phenomenology based on the Dutch school of phenomenology. This study followed purposeful sampling in which ten participants six women and four men with a mean age of 54.4 years were selected. The proposed research was approved by the Institutional Review Boards at the American University of Beirut and Duquesne University. In-depth semi-structured interviews along with observation-field notes were used as the source for data collection. Data were analyzed using the hermeneutic phenomenological …

Economic Instruments For Water Pollution Control Policy Making Issues: Experiences From Colombia, Monica Mildrei Montoya

Electronic Theses and Dissertations

As part of the pollution control effort several developing countries have established economic-based initiatives to improve environmental quality. In this study the Colombian water pollution charge, which was implemented in 1997, is analyzed. The two key questions that this study attempts to answer are: 1) Does the performance of the pollution charge program in Colombia undermine the notion that economic instruments are not feasible in developing countries? 2) Which factors determine the performance of the water pollution charge program across regional environmental agencies in Colombia?

The answer to these questions provides valuable information for developing countries looking for more efficient …

Mathematical Modeling Of Smallpox Withoptimal Intervention Policy, Niwas Lawot

Electronic Theses and Dissertations

In this work, two differential equation models for smallpox are numerically solved to find the optimal intervention policy. In each model we look for the range of values of the parameters that give rise to the worst case scenarios. Since the scale of an epidemic is determined by the number of people infected, and eventually dead, as a result of infection, we attempt to quantify the scale of the epidemic and recommend the optimum intervention policy. In the first case study, we mimic a densely populated city with comparatively big tourist population, and heavily used mass transportation system. A mathematical …