Digital Commons Network^™

Treasure, Karen M. Perkins

Electronic Theses and Dissertations

Long after a brutal series of events resulted from her power exchange relationship, Treasure Montgomery’s recovery from post-traumatic stress disorder is hampered by relationships with family members and the legal difficulties of her foster daughter.

Effect Of Total Body Iron On Metabolic Dysfunction Among U.S. Females In The Nhanes 2003-2010, Aged 12-49., Joseph Michael Carhart

Electronic Theses and Dissertations

Experimental and epidemiological studies have reported positive associations between iron parameters and metabolic dysfunction including: Type 2 diabetes mellitus (T2DM) (1-6), metabolic syndrome (7-15), non-alcoholic fatty liver disease (NAFLD) (16-22) and insulin resistance (23,24) with a number of studies showing that reductions in total body iron via dietary modification (e.g., reducing red meat intake) or phlebotomy lead to increases in insulin sensitivity (25), decreases in insulin resistance (26), and reductions in the prevalence of complications associated with T2DM (5, 27), metabolic syndrome (28) and NAFLD (22, 29). Moreover, the risk associated with these outcomes and total body iron differ between …

Challenging The Self : An Examination Of The Media's Role In Creating Idealized Bodies And The Artists That Challenge Them., Jessica Oberdick

Electronic Theses and Dissertations

Seeking to understand the media’s influence over society, and the way the media motivate us to conform to specific ideals, this thesis focuses on how female bodies in particular are consistently idealized and objectified in mainstream media. Through television, print, and the internet, the media serve as our world’s main means of mass communication. Noting this, this text seeks to understand the female body’s historical objectification through art history and genres of the nude, how this has transferred to contemporary media, and finally states that these stereotypes and norms can be challenged through the work of contemporary artists. By reclaiming …

The Role Of Kinases And Phosphatases In The Pathobiology Of Porphyromonas Gingivalis., Sarah Whitmore

Electronic Theses and Dissertations

Periodontal diseases result from the interplay between the dysregulation of the host inflammatory response and the actions of a dysbiotic bacterial community. These chronic inflammatory conditions affect persons on a worldwide scale. P. gingivalis is strongly implicated as a key periodontal pathogen in the more severe manifestations of periodontal diseases such as periodontitis. A core element of P. gingivalis pathogenicity is its dysregulation of innate immunity, including suppression of IL-8 production by gingival epithelial cells. The NF-κB family of related transcription factors plays a central role in regulating many important aspects of innate immune responses. NF-κB RelA/p65 homodimers regulate transcription …

A Risky Business : Examining The Prevalence And Correlates Of Post Traumatic Stress Disorder Symptomology And Social Support In Kentucky's Adult Correctional Staff., Ashley Terrell French

Electronic Theses and Dissertations

The purpose of this study was to determine the prevalence and correlates of post traumatic stress disorder (PTSD) symptomology among correctional staff, using a sample of staff who work in an adult facility for the Kentucky Department of Corrections (KY DOC). Participants (N=775) were asked to complete a written survey to indicate not only demographic variables (age, race, education, and gender) but also the amount of violent and traumatic events experienced, the duration of employment within the KY DOC, whether they were assigned to a custodial/security role, and whether they worked in a maximum security facility. Furthermore, their perceived level …

Factors Associated With Federal Student Loan Default Among Borrowers In A Statewide System Of Community And Technical Colleges., Brittany Inge

Electronic Theses and Dissertations

Community colleges serve as a gateway to higher education for millions of American college students. Open-door admission policies and federal student aid facilitate the access that two-year public institutions provide, particularly for students who are under-resourced or academically under-prepared for college. However, a substantial number of community college students who use federal student loans to pay for college ultimately fail to repay the loans, yielding negative consequences for borrowers, institutions, and taxpayers.

By employing a Hierarchical Generalized Linear Model (HGLM) this study investigates individual-level and institution-level factors associated with federal student loan default among borrowers who attended a two-year public …

Artificial Olfactory System For Multi-Component Analysis Of Gas Mixtures., Alexander Aleksandrovich Larin

Electronic Theses and Dissertations

Gas analysis is an important part of our world and gas sensing technology is becoming more essential for various aspects of our life. A novel approach for gas mixture analysis by using portable gas chromatography in combination with an array of highly integrated and selective metal oxide (MOX) sensors has been studied. We developed a system with small size (7 x 13 x 16 inches), low power consumption (~10 W) and absence of special carrier gases designed for portable field analysis (assuming apriori calibration). Low ppb and even sub-ppb level of detection for some VOCs was achieved during the analysis …

Synthesis Of 2,4,6-Substituted Pyrrolo[2,3-D]Pyrimidines As Potential Anticancer Agents, Si Yang

Electronic Theses and Dissertations

This thesis mainly focuses on the introduction of the background and work have been done in the areas of antifolates development, such as folate function, its three uptake mechanisms inside human cells, antifolates’ role in chemotherapy, et. al. In addition, the Structure-Activity-Relationship design rationale for the series of antifolates will also be discussed. Nevertheless, the details of synthesizing these pyrrolo[2,3-d]pyrimidines as potential antifolates have been described, including chemistry reviews on the pyrrolo[2,3-d]pyrimidine scaffold, and the challenges encountered and the solutions how to solve or improve in order to achieve better yield.

Deficiency Of Rdh10 Causes Cleft Secondary Palate In Mouse., Swetha Raja

Electronic Theses and Dissertations

The focus of this project is to understand the role of Retinoic Acid (RA) produced by RDH10-mediated metabolism of Vitamin A in palate development. For 80 years now, we have known that dietary restriction of RA/Vitamin A can cause cleft palate but we have failed to understand how RA deficiency causes cleft palate. Our gap in knowledge about how RA deficiency causes cleft palate is mainly owing to the fact that we lack a model system to study such defects. The aim of this thesis research project was to determine if conditional inactivation of the Vitamin A metabolic gene Rdh10 …

Per Pupil Expenditure, Graduation Rates, And Act Scores In Tennessee School Districts, Jay Irvin

Electronic Theses and Dissertations

The purpose of this study was to investigate and identify possible relationships between academic achievement, as measured by high school graduation rate and ACT composite scores of individual school districts within the state of Tennessee, and the per-pupil expenditure of each district. Research was conducted to determine whether a significant difference existed in academic achievement measures (high school graduation rate, ACT composite score) among school districts in the state of Tennessee that were classified as above average, average, and below average in relation to their per-pupil expenditure (PPE) in the 2013-2014, 2014-2015, and 2015-16 school years.

Ex post facto data …

Functional Data Analysis Methods For Predicting Disease Status., Sarah Kendrick

Electronic Theses and Dissertations

Introduction: Differential scanning calorimetry (DSC) is used to determine thermally-induced conformational changes of biomolecules within a blood plasma sample. Recent research has indicated that DSC curves (or thermograms) may have different characteristics based on disease status and, thus, may be useful as a monitoring and diagnostic tool for some diseases. Since thermograms are curves measured over a range of temperature values, they are often considered as functional data. In this dissertation we propose and apply functional data analysis (FDA) techniques to analyze DSC data from the Lupus Family Registry and Repository (LFRR). The aim is to develop FDA methods to …

Job Embeddedess Of Nurses Working In South Central Appalachia’S North Carolina Counties, Susan L. Adams Mrs.

Electronic Theses and Dissertations

Nurses working in the North Carolina counties of South Central Appalachia (NC-SCA) are a unique subset of nursing professionals. A continued nursing shortage is projected in this area while staffing has improved in other areas of SCA. The purpose of this research was to ascertain the level of job embeddedness of nurses working in NC-SCA in order to offer guidance regarding retention of nurses working in this area. Actively working licensed practical nurses, registered nurses, and advanced practice nurses (nurse practitioners, certified nurse midwives, clinical nurse specialists, and certified registered nurse anesthetists) from 29 North Carolina counties included in South …

Preschool Enrollment And Elementary School Achievement In An East Tennessee School District, Derek Voiles

Electronic Theses and Dissertations

The purpose of this study was to determine if a significant difference in achievement scores exists among students based on whether or not they attended preschool as measured by standardized achievement reading-language arts and math scores on the Tennessee Comprehensive Achievement Program assessment for fourth grade students in a single East Tennessee school district. The variables of grade level and preschool attendance were considered. The population consisted of fourth grade students during the 2014-2015 school year. Data were gathered from the Tennessee Comprehensive Assessment Program achievement test scores obtained from the 2014-2015 school year and from the school district’s preschool …

Women In Recovery: Perceptions In Transition To Community College, Mandi Walker

Electronic Theses and Dissertations

Substance abuse is an area of concern for college administrators, and they have implemented campus programming in an attempt to address it. Additionally, prior researchers have studied substance abuse on college campuses in order to better understand how substance abuse affects student success. However, limited research exist that addresses the unique perspective of college students who are in recovery from substance abuse, and most studies were conducted in 4-year institutions rather than community colleges. This qualitative case study explored the transition experiences of female students in recovery who attend community college or have recently graduated. The sample included students from …

Identities And Persistence Of Family Farm Operators, Parker T. Arnold

Electronic Theses and Dissertations

This study focuses on the identities of family farm operators and the challenges to maintaining viable farm operations in today’s agricultural economy. Employing a grounded qualitative approach, the author conducted 18 in-depth interviews with principal farm operators from Iowa and Tennessee. Using the insights of farmers from geographically different agricultural regions, this study notes how preserving family histories, socialization processes, and farming as a moral career inform operators’ understandings of themselves and the work they do. The analysis also focuses on how family farm operators contend with a globalized agricultural economy and the moral and ethical concerns of managing a …

The Bobsled Push Start: Influence On Race Outcome And Push Athlete Talent Identification And Monitoring, Alex Harrison

Electronic Theses and Dissertations

Bobsled is an Olympic sport that has progressed from rudimentary in the 1800’s to highly technological replete with biomechanical analyses and investment in engineering from the world’s top engineers. Little to no investigation has been carried out on all the tracks and the interrelationship between various measures of starts and sled-travel down-track. Further, little quality research has been produced in the athletic characteristics required for high-level competition in bobsled.

The present manuscript investigates the reliability of, and interrelationship between, start time, start velocity, split times, and finish times in World Cup 2- and 4-man bobsled competition. A strong relationship between …

Discharge Readiness For Families With A Premature Infant Living In Appalachia, Kathy Zimmerman

Electronic Theses and Dissertations

With increased advances in technology, the overall survival rates in the Neonatal Intensive Care Unit (NICU) for premature infants at lower gestational ages, has also increased. Although premature infants survive at lower gestational ages, they are often discharged to home with unresolved medical issues. While the birth of a new baby for parents is a joyous occasion, they often have difficulty coping and transitioning into a parental role. Premature infants also have ongoing complications such as difficulty with feeding, developmental delays in growth, and long-term eye and respiratory complications. As a result of chronic health sequelae, premature infants require extensive …

Pre-Licensure Nursing Students’ Perceptions Of Safety Culture In Schools Of Nursing, Kristen Hershey

Electronic Theses and Dissertations

Safety culture has been demonstrated to be a key factor in high-reliability organizations (HROs), yet healthcare has not achieved a safety culture as seen in HROs despite decades of effort. Student nurses are enculturated into their profession during their pre-licensure education. This period offers an excellent opportunity to teach students the values, norms, and practices of safety culture. However, little is known about the state of safety culture in schools of nursing.

The purpose of this study was to examine the state of patient safety culture as perceived by students in pre-licensure nursing programs in the US using a modified …

Social-Ecological Factors Affecting Patient Shield Use Among Radiologic And Computed Tomography Technologists, Megan Housenick-Lee

Electronic Theses and Dissertations

Medical radiation is estimated to contribute to over 200,000 deaths annually. Recent increases in the use of radiation-producing medical imaging examinations have led to increasing cumulative radiation dose to the general public. Multiple measures have been taken to address this alarming trend, including physician education, technologist education on dose reduction, and equipment-facilitated dose reduction techniques. Shield use can reduce the primary beam by up to 95%. Medical imaging technologists are the primary individuals responsible for applying shielding during an examination. Currently, literature shows that technologists are not shielding individuals as often as they should.

After pilot testing, medical imaging technologists …

Access To Healthy Foods: A Descriptive Analysis Of Farmers’ Markets, Food Deserts & Usda Food Assistance Programs In Tennessee Census Tracts, Twanda D. Wadlington

Electronic Theses and Dissertations

Food deserts are a growing problem in the United States, and occur in areas of low-income where people have limited access to healthy foods. In response, the presence of farmers’ markets has grown exponentially, and improved healthy food access. Additionally, the USDA has strived to connect families to healthy foods through food assistance programs such as the Supplemental Nutrition Assistance Program (SNAP), the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), and the Senior Farmers’ Market Nutrition Program (SFMNP). This study investigated the relationship between farmers’ markets, their acceptance of food assistance benefits, and their locations within Tennessee …

Young Adult Literature And Empathy In Appalachian Adolescents, Kelsey R. Kiser

Electronic Theses and Dissertations

Based on recent research concluding that fiction can increase empathy, this project examines how multicultural young adult literature may encourage empathy in Appalachian adolescents. Empathy encourages prosocial behaviors, but evidence suggests that young adults’ ability to empathize has declined in recent decades. In addition, Appalachia in particular is still a relatively homogenous region as it is majority white, protestant Christian, and heteronormative. Because of this, young adults in Appalachia may encounter few diverse perspectives in real life; multicultural young adult literature can provide diverse perspectives with which teenagers can empathize in a region where they might not have similar opportunities …

An Exploration Of Dementia Friendly Communities From The Perspective Of Persons Living With Dementia, Catherine Hebert

Electronic Theses and Dissertations

The growing global prevalence of dementia coupled with a shift in public perception from a hopeless disease to the possibility of living well with dementia has led to the formation of dementia friendly communities (DFC). DFCs are a new phenomenon in the United States, with a gap in knowledge on input from people living with dementia (PLWD). This study investigated DFCs from the perspective of PLWD in Western North Carolina, with the following research questions:

1. How are interactions and relationships experienced by persons living with dementia in the community?
2. How is community engagement experienced by PLWD?
3. To what extent and …

Teacher Perceptions Of Using Positive Behavior Interventions And Supports As Behavioral Interventions In A Pre-K-5 Elementary School: A Phenomenological Study, Meghann Roberts-Clawson

Electronic Theses and Dissertations

Teachers’ Perceptions of Using Positive Behavior Interventions and Supports as Behavioral Interventions in a Pre-K-5 Elementary School: A Phenomenological Study by Meghann E. Roberts-Clawson This qualitative study addresses teacher perceptions of using positive behavior interventions and supports (PBIS) as positive behavioral interventions. This phenomenological study was conducted within a Pre-K-5 elementary school in northwestern North Carolina. In order to collect qualitative data, personal individualized interviews were conducted from a purposeful sample of teachers in the school who have experience implementing more intensive positive behavioral interventions. By analyzing data derived from the interviews and classroom and individualized documentation, the researcher was …

How The Collective Impact Model Can Help Hispanic Students In East Tennessee Excel In Higher Education, Edwin Soto

Electronic Theses and Dissertations

This research project focuses on helping Hispanic students in the East Tennessee region excel in higher education with existing resources from various organizations. Hispanic high school students were identified to complete a survey. Findings showed that these students are facing legal, financial and social challenges when thinking about higher education. Even though these students are facing these challenges, they still want to pursue higher education in order to make a positive impact in their communities. The collective impact idea is proposed as part of the solution for this social complex problem. Since it is impossible for an individual to solve …

Levels Of Feedback Observed In Kindergarten Classrooms: Perceptions And Reality, Jacqueline Johnson

Electronic Theses and Dissertations

The most powerful influence on student achievement is the classroom teacher and the most effective instructional strategy teachers can use to increase student learning and achievement is effective feedback (Hattie & Timperley, 2007). The research on teacher feedback in kindergarten classrooms is scarce therefore this study helps reduce the void in the literature on the importance of teacher feedback in kindergarten classrooms.

The purpose of this study was to examine effective teachers’ perceptions of the amount and kind of feedback they provide to their students and to determine if their perceptions match the feedback they actually provide. The participants in …

Thinking Before You Act: A Constructive Logic Approach To Crafting Performance-For- Development Narrative, Angela Duggins

Electronic Theses and Dissertations

The intent of this thesis was to test the feasibility of constructing performance-for-development narrative using a constructive logic approach. I created an equation which expressed the sum of non-human-elements as the sum of a narrative with each element serving as a variable. I used a review of persuasion literature to provide insight into the selection and manipulation of each variable. I provided my family as a hypothetical example and used my knowledge of their preferences and communication styles in conjunction with the literature and the equation to craft a narrative which might increase pro-school attitudes in other families like my …

The Algz/R Two-Component System Is Responsible For Attenuation Of Virulence In Pseudomonas Aeruginosa, Danielle A. Williams

Electronic Theses and Dissertations

Pseudomonas aeruginosa is an important opportunistic pathogen. Many P. aeruginosa virulence factors are regulated by the AlgZ/R two component system. AlgZ is the sensor histidine kinase which phosphorylates AlgR, the response regulator. AlgR activates transcription of different gene targets based upon its phosphorylation state. The genes that encode AlgZ and AlgR are transcribed in an operon. While regulation of algR expression has been well studied, regulation of algZ expression has not. Using a pilW mutant in concert with algZTF-lacZ transcriptional fusion, we conducted a transposon mutagenesis to identify algZ regulators. We identified an unknown autoregulatory loop. The type …

Parental Perceptions Of Preschool-Age Children’S Literacy Development In A Rural Appalachian Community, Kimberly Austin

Electronic Theses and Dissertations

Early Childhood educators agree on the significant influence of a parent on a child’s literacy development. The environment a parent provides, in addition to the opportunities a child has in the early years, have a major influence on a child’s literacy development. This study sought to determine how parents in a low-income socioeconomic group perceived literacy development and how their preschool-age children performed on an emergent literacy assessment. The 64 study participants were recruited from a Head Start program in the central Appalachian Mountains. An overwhelming majority of participants were mother/child dyads, every participant spoke English as a primary language, …

Impact Of A Technology Based Intervention Package On The Inappropriate Behavior Of A Child With Severe Disability, Amani Alshehri

Electronic Theses and Dissertations

One useful strategy to support students with intellectual and developmental disability (IDD) to promote appropriate behaviors across environments and gain the social skills is using social stories. In addition, experts have recognized iPads and apps were associated with less challenging behavior and more academic engagement over traditional materials (Lee, Lang, Davenport, Moore, Rispoli, Meer, & Chung, 2013). The focus this study was to examine the effectiveness of an intervention package featuring social stories delivered via an iPad and simultaneous prompting on frequency of targeted challenging behavior and comprehension of the social story of a student with IDD. A single-subject multiple …

Modeling Student Enrollment At Etsu Using A Discrete-Time Markov Chain Model, Lohuwa Mamudu

Electronic Theses and Dissertations

Discrete-time Markov chain models can be used to make future predictions in many important fields including education. Government and educational institutions today are concerned about college enrollment and what impacts the number of students enrolling. One challenge is how to make an accurate prediction about student enrollment so institutions can plan appropriately. In this thesis, we model student enrollment at East Tennessee State University (ETSU) with a discrete-time Markov chain model developed using ETSU student data from Fall 2008 to Spring 2017. In this thesis, we focus on the progression from one level to another within the university system including …