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Regulation Of Extra-Pituitary Prolactin In Monocytes And Macrophages, Richard Barrett Jan 2018

Regulation Of Extra-Pituitary Prolactin In Monocytes And Macrophages, Richard Barrett

Electronic Theses and Dissertations

Recently it has been shown that leukocytes are capable of producing prolactin (PRL). Evidence of extra-pituitary PRL (ePRL) production is so far been limited to primates and is not shared across other mammal species such as mice and rats. While ePRL is characterized as an identical protein to traditional pituitary PRL, it is controlled under an alternative promoter and is thus regulated differently from pituitary PRL. Little is known about what regulates ePRL or its direct role in human physiology, but given that PRL has well over 300 described functions, it is likely that the autocrine and paracrine effects of …


Effects Of Electronic Media Messages On The Perceived Self-Efficacy Of Pedestrian Commuters Living In The Unincorporated Central Florida Community Of Conway, Daniel Stephens Jan 2018

Effects Of Electronic Media Messages On The Perceived Self-Efficacy Of Pedestrian Commuters Living In The Unincorporated Central Florida Community Of Conway, Daniel Stephens

Electronic Theses and Dissertations

Urban pedestrianism is increasingly perceived as a dangerous form of travel. While roadway design has been historically scaled to cars instead of people, planning professionals are now re-thinking their approach to make roads more inclusive for all travelers. Scholars, however, have learned harbored fear can trump behavior even under ideal travel conditions. Such fear can adversely impact perceived pedestrian self-efficacy, which is the self-generated internal assessment or belief in a traveler's agentive abilities to navigate the travel environment. The challenge thus becomes twofold: improve the built environment while bolstering traveler confidence. The following study, therefore, employed a qualitative phenomenological research …


The Intersection Of Race And Class In Maternity Leave: Who's Left Out?, Christine Ittai Jan 2018

The Intersection Of Race And Class In Maternity Leave: Who's Left Out?, Christine Ittai

Electronic Theses and Dissertations

Maternity leave is a critical work-family policy that affects over two-thirds of the working U.S. female population. Although it has been studied extensively, especially since the passage of the Family and Medical Leave Act of 1993, the majority of the research has focused on White, middle-class, married, and educated working mothers. There is a plethora of information about access to maternity leave, utilization of maternity leave, length of maternity leave, and compensation during leave. However, there are several limitations in the research. A majority of studies use outdated datasets; measure family leave as a proxy for maternity leave; study paid …


A Qualitative Analysis Of Key Concepts In Islam From The Perspective Of Imams, Chandler Dobiyanski Jan 2018

A Qualitative Analysis Of Key Concepts In Islam From The Perspective Of Imams, Chandler Dobiyanski

Electronic Theses and Dissertations

The continuous occurrence of terrorist attacks in the name of Islam has shown this ideology and its tenets are at least somewhat connected to jihadists committing attacks in its name. This ideology in terms of 13 themes was investigated by the researcher in 58 sermons outlined in the tables in the appendix. These themes include: brotherhood, death, freedom, human rights, justice and equality, love, oppression, peace and treaty, self-defense, sin, submission, terrorism and truth vs. lies. The researcher used a sample of 10 sermons from U.S.- born imams and 10 sermons from foreign-born imams as the basis for the analysis …


Violence, Religion And Politics: The Late Republic And Augustan Age, Matthew Tuggle Jan 2018

Violence, Religion And Politics: The Late Republic And Augustan Age, Matthew Tuggle

Electronic Theses and Dissertations

Religion in the Late Republic was fused to politics. This study considers the relationship between violence, religion, and politics in the Late Republic and Augustan Age. It contends that Roman religion could encourage or discourage violence based upon the circumstances. The strain of Roman expansion on its political and religious institutions contributed to the civil discord that characterized the Late Republic, which created circumstances that were flexible enough for perspectives on each side to see the violence as justified. The ambition of a tribune, a sacrosanct office, could lead to circumvention of the traditional practices of the Senate, causing a …


An Analysis Of Choice-Making As A Means To Decrease The Frequency Of Self-Injurious Behaviors In Students With Severe Disabilities, Melanie Olson Jan 2018

An Analysis Of Choice-Making As A Means To Decrease The Frequency Of Self-Injurious Behaviors In Students With Severe Disabilities, Melanie Olson

Electronic Theses and Dissertations

This single case multiple baseline research study examined choice-making as a means to decrease the frequency of self-injurious behaviors in six students with severe disabilities. Five males and one female between the ages of 14 and 21 participated in the five-week intervention. The following research questions were addressed: 1) Does the choice-making intervention reduce hitting, biting, and self-injurious behaviors? 2) How much time does the choice-making intervention add to the classroom teacher's preparation? 3) What costs are associated with the choice-making intervention during an average lesson? The choice-making intervention was associated with positive behavioral outcomes for all of the students. …


Managing An Epidemic: Zika Interventions And Community Responses In Belize, Deven Gray Jan 2018

Managing An Epidemic: Zika Interventions And Community Responses In Belize, Deven Gray

Electronic Theses and Dissertations

Implementing effective health interventions in recent epidemics has been difficult due to the potentially global nature of their spread and sociocultural dynamics, raising questions concerning how to develop culturally-appropriate preventive measures, and how these health threats are understood locally. In Belize, health policy makers have only been marginally effective in managing infections and mosquito vectors, and Zika has been declared endemic in multiple regions of the country, particularly on the island of Caye Caulker. With one locally confirmed case of microcephaly on this small island already, this disease has the potential to severely impact the health and wellness of pregnant …


Embryonic Stem Cell-Derived Exosomes Inhibit Doxorubicin-Induced Pyroptosis In Cell Culture Models, Zahra Tavakoli Dargani Jan 2018

Embryonic Stem Cell-Derived Exosomes Inhibit Doxorubicin-Induced Pyroptosis In Cell Culture Models, Zahra Tavakoli Dargani

Electronic Theses and Dissertations

Doxorubicin (Dox) is a potent chemotherapeutic drug used for the treatment of various cancers. Unfortunately, its use is limited as Dox induces adverse cardiotoxicity (DIC) and muscle toxicity (DIMT), which are mediated through oxidative stress, ER stress, and inflammation. However, it remains unknown whether Dox induces an inflammation mediated cell death, called “pyroptosis”. The current study is designed to determine whether Dox induces pyroptosis in cardiac and muscle cell culture models. Moreover, the protective effects of embryonic stem cell-derived exosomes (ES-Exos) in inhibiting pyroptosis will also be determined. For this purpose, we designed two different cell culture models using H9c2 …


How Much Is Enough? Trauma Recall And The Exposure Therapy Process, Krystal Morrison Jan 2018

How Much Is Enough? Trauma Recall And The Exposure Therapy Process, Krystal Morrison

Electronic Theses and Dissertations

Prevailing theoretical models of posttraumatic stress disorder (PTSD) as well as exposure therapy (EXP) methodology suggest that recall of a trauma is crucial to altering the conditioned fear response associated with PTSD (Benito & Walther, 2015; Craske et al., 2008; Foa & Kozak, 1986). However, it is unclear whether limited recall of the event impacts the EXP process and treatment outcomes. This study examined whether incomplete trauma recall affected pre-treatment PTSD severity, Initial Fear Activation (IFA), Overall Fear Activation (OFA), Within-Session Habituation (WSH), Between-Session Habituation (BSH; overall extinction), average length of EXP sessions, number of EXP sessions, and post-treatment PTSD …


Interaction Between Income, Health Insurance, And Self-Rated Health: A Path Analysis., Atalie Ashley West Jan 2018

Interaction Between Income, Health Insurance, And Self-Rated Health: A Path Analysis., Atalie Ashley West

Electronic Theses and Dissertations

The political focus of equitable health outcomes in the United States have long centered on access to medical care. However, there is compelling evidence that access to medical care is only the bare minimum necessary to achieve health, and the true influence of health insurance on health is still unclear. Widely accepted models of health estimate that less than 20% of health outcomes can be attributed to clinical care, while greater than 50% is related to social and economic determinants of health, with income being the most consistent predictor. As a result, this study investigated whether earned income is related …


Knowledge And Attitudes Regarding The Recent Zika Outbreak Among A Sample Of South Florida Residents, Mohamed Elakkari Jan 2018

Knowledge And Attitudes Regarding The Recent Zika Outbreak Among A Sample Of South Florida Residents, Mohamed Elakkari

Electronic Theses and Dissertations

South Florida has had the largest number of U.S. Zika infection cases during the recent outbreak. This study aimed at assessing South Floridians' basic knowledge, perceptions of the seriousness and susceptibility to Zika infection, their information sources and needs, as well as their attitudes towards the protective measures proposed by the CDC. We also wanted to assess whether any of those factors have affected the frequency of participants' undertaking of the protective behaviors. To this end, we designed an online questionnaire and surveyed the responses of five hundred South Floridians (Age=18-78 years). We found significant gaps in participants' knowledge about …


Dissecting The Components Of Neuropathic Pain, Dale George Jan 2018

Dissecting The Components Of Neuropathic Pain, Dale George

Electronic Theses and Dissertations

Pain is a public health issue affecting the lives of nearly 116 million adults in the US, annually. Understanding the physiological and phenotypic changes that occur in response to painful stimuli is of tremendous clinical interest, but, the complexity of pain and the lack of a representative in vitro model hinders the development of new therapeutics. Pain stimuli are first perceived and transmitted by the neurons within the dorsal root ganglia (DRG) which become hyperexcitable under these conditions. It has now been established that satellite glial cells (SGCs) that ensheathe the DRG cell body actively contribute to this neuronal dysregulation. …


Split Aptameric Turn-On Fluorescence Sensor For Detection Of Sequence Specific Nucleic Acid At Ambient Temperature, Nanami Kikuchi Jan 2018

Split Aptameric Turn-On Fluorescence Sensor For Detection Of Sequence Specific Nucleic Acid At Ambient Temperature, Nanami Kikuchi

Electronic Theses and Dissertations

Nucleic acid amplification tests (NAATs) enable sensitive detection of low density infections that microscopy and rapid diagnostic test are not capable of detecting. They enable quantitative and qualitative nucleic acid detection, genotype analysis, and single nucleotide polymorphism (SNP) detection. Current state of the art molecular probes used with NAATs includes molecular beacon (MB), Taqman and its variations. This work presents novel molecular probe designed from Spinach and Dapoxyl aptamers. The aptamers are split into two parts (split aptamer), allowing greater sensitivity and selectivity towards fully complementary nucleic acid analyte. The major advantage of split aptamer probe over state-of-the-art fluorescent probes …


Leadership Development Programs In College Athletics: An Exploration Of The Student-Athlete Experience, Jeffrey O'Brien Jan 2018

Leadership Development Programs In College Athletics: An Exploration Of The Student-Athlete Experience, Jeffrey O'Brien

Electronic Theses and Dissertations

The purpose of this study was to explore the lived experiences and perceptions of twelve college student-athletes, from two NCAA Division I institutions, who participated in leadership development programs provided by their athletic department. There is a demonstrated need for this level of exploration as evidenced by the growing trend of college athletic departments providing leadership development programming for their respective student-athlete populations. However, there is not a commensurate level of scholarship related to the effectiveness of these programs, nor is there an understanding of the lived experiences of the student-athlete participants that is grounded in research. Therefore, this qualitative …


Examining Faculty Socialization Through The Lens Of Transformative Learning, Jennifer Plant Jan 2018

Examining Faculty Socialization Through The Lens Of Transformative Learning, Jennifer Plant

Electronic Theses and Dissertations

Socialization may be described as a process in which an individual learns and takes on the knowledge, values, attitudes, and expectations of a group within an organization (Corcoran & Clark 1984; Staton & Darling, 1989), ultimately leading to the development of a professional identity that includes attributes of the group (Merton, Reader, & Kendall, 1957). Much of the literature regarding professional and organizational socialization experiences of new faculty focus solely on either clinically trained faculty or academically trained faculty, with minimal research comparing the professional and organizational socialization experiences of both degree types. Therefore, this research study explored the professional …


Analysis Of United States Congresswomen's Tweets During The 2017 And 2018 Women's Marches Against Donald Trump In The U.S., Cynthia Nnagboro Jan 2018

Analysis Of United States Congresswomen's Tweets During The 2017 And 2018 Women's Marches Against Donald Trump In The U.S., Cynthia Nnagboro

Electronic Theses and Dissertations

This thesis analyzes the content of United States Congresswomen's Tweets during the 2017 and 2018 Women's March on Washington (WMW). The research is based on the media framing theory. Previous literature has asserted that women in Congress place a higher priority on women's issues than other policy legislations. This study sought to determine the degree to which these assertions were true by analyzing Congresswomen's tweets during the WMW. A total of 1950 tweets from Congresswomen were collected during four days and analyzed for content and tone. Findings in this thesis invalidate that claim as the results of the investigation shows …


The Evolution Of Shared Responsibility And Instructional Risk Communication In Brazil's Campaign Against The Zika Virus, Rodrigo Soares Jan 2018

The Evolution Of Shared Responsibility And Instructional Risk Communication In Brazil's Campaign Against The Zika Virus, Rodrigo Soares

Electronic Theses and Dissertations

This study provides an evaluation of instructional risk communication practices in Brazil's response to the Zika virus during the 2016/2017 campaign. The communication was instructionally focused, explaining the way the disease is transmitted, what to do if the person is infected, and characteristics of the mosquito. The authorities also tried to convince the publics that, because the mosquito breeds in everyone's houses and apartments, everyone could be part of the solution. The social, economic and cultural characteristics of the country, the population's low levels of health literacy, and a long-lasting government credibility problem in the country make Brazil's fight against …


Recruiting Followers For The Caliphate: A Narrative Analysis Of Four Jihadist Magazines, Andrea Madrazo Jan 2018

Recruiting Followers For The Caliphate: A Narrative Analysis Of Four Jihadist Magazines, Andrea Madrazo

Electronic Theses and Dissertations

This study identifies and compares the methods of recruitment used by three prime jihadist organizations through their online magazines. The successful recruitment efforts and growth as a threat by the Islamic State of Iraq and Shām (ISIS), Al-Qaeda, and Al-Shabaab are attributed, in part, to the widespread popularity and accessibility of Dabiq and Rumiyah (published by ISIS), Inspire (published by Al-Qaeda), and Gaidi Mtaani (published by Al-Shabaab). In order to best examine the techniques of persuasion and propaganda to recruit new followers, the theoretical approach of compliance-gaining theory and methodological approach of a narrative analysis are applied. The author analyzed …


The Impact Of A Neurofeedback Training Intervention On College Students' Levels Of Anxiety, Stress, Depression, And Cortisol, Caitlyn Bennett Jan 2018

The Impact Of A Neurofeedback Training Intervention On College Students' Levels Of Anxiety, Stress, Depression, And Cortisol, Caitlyn Bennett

Electronic Theses and Dissertations

Anxiety, depression, and stress are three of the most common experiences that impact college student functioning and academic achievement. At least one in six college students struggle with anxiety, increasing risk for developing depressive symptoms or disorders that further impact wellness. However, as mental health concerns increase across campuses, universities are not equipped to meet the demand of mental health support for college students. Neurofeedback (NF) training presents as an innovative intervention to treat anxiety, depression, and stress as it is designed to regulate brain processes in an effort to increase more effective brain functioning. A quasi-experimental, nonequivalent control group …


An Exploratory Analysis Of A Five Minute Speech Sample Of Mothers Of Children With Selective Mutism, Lisa Kovac Jan 2018

An Exploratory Analysis Of A Five Minute Speech Sample Of Mothers Of Children With Selective Mutism, Lisa Kovac

Electronic Theses and Dissertations

Selective mutism (SM), an anxiety disorder wherein children have difficulty speaking or communicating when they are uncomfortable, is relevant for the early childhood population as symptoms often manifest upon school entry (Steinhausen & Juzi, 1996) and early treatment leads to better treatment prognosis (Oerbeck, Stein, Wentzel-Larsen, Langsrud & Kristensen, 2014). Bergman, Gonzalez, Piacentini and Keller, (2013) utilized an integrative behavioral treatment for children (ages 4-8) with SM and reported a 75% treatment responder status after 24 weeks of therapy. Their mothers are the focus of this study. This exploratory study examined the content of Five Minute Speech Samples at baseline …


Audience Engagement In Theatre For Young Audiences: Teaching Artistry To Cultivate Tomorrow's Theatre-Goers, Julie Woods-Robinson Jan 2018

Audience Engagement In Theatre For Young Audiences: Teaching Artistry To Cultivate Tomorrow's Theatre-Goers, Julie Woods-Robinson

Electronic Theses and Dissertations

As a teaching artist and theatre educator, I believe an important part of the theatre-going experience is when an audience engages with the play before and after the performance: learning about context, analyzing the production, and identifying themes relevant to the play. Theatre is a powerful teaching tool with regards to empathy and political and social awareness, but also, for young audiences, theatre can help students understand content in other subject areas like language arts, history, and even health. This thesis develops best practices for creating effective audience engagement with young people in theatre in the form of Field Trip …


The Power Of Play: Creating A Theatre For The Very Young Experience, Maria Katsadouros Jan 2018

The Power Of Play: Creating A Theatre For The Very Young Experience, Maria Katsadouros

Electronic Theses and Dissertations

The opportunity to enhance the sense of fulfillment necessary in revolutionizing and liberating a person's daily life, regardless of their age, can be found in the manifestation of play. It is through the acknowledgment of instinct, nature, and discovery that play reveals its power. As a Theatre for the Very Young (TVY) practitioner, I utilize creative play to inspire exploration and innovation among students under the age of six. However, what are the ways in which theatre, specifically TVY, invites all generations of people to experience the power of play? This thesis documents the three-year development of When Pigs Fly, …


Three Studies Examining Auditors' Use Of Data Analytics, Jared Koreff Jan 2018

Three Studies Examining Auditors' Use Of Data Analytics, Jared Koreff

Electronic Theses and Dissertations

This dissertation comprises three studies, one qualitative and two experimental, that center on auditor's use of data analytics. Data analytics hold the potential for auditors to reallocate time spent on labor intensive tasks to judgment intensive tasks (Brown-Liburd et al. 2015), ultimately improving audit quality (Raphael 2017). Yet the availability of these tools does not guarantee that auditors will incorporate the data analytics into their judgments (Davis et al. 1989; Venkatesh et al. 2003). The first study investigates implications of using data analytics to structure the audit process for nonprofessionalized auditors. As the public accounting profession continues down a path …


Biomechanical Characterization Of Video-Recorded Short-Distance Falls Involving Children Equipped With A Biometric Device: A Pilot Study., Bret A Hilt Jan 2018

Biomechanical Characterization Of Video-Recorded Short-Distance Falls Involving Children Equipped With A Biometric Device: A Pilot Study., Bret A Hilt

Electronic Theses and Dissertations

Falls are commonly used as a false history by caregivers to conceal child abuse. Determining biomechanical compatibility is a key aspect in differentiating abuse from accident. Current forensic approaches are limited in assessing biomechanical compatibility of short-distance falls involving children due to a lack of reliable witnessed falls with known injury outcomes. The goals of this pilot study were to characterize biomechanical measures and to examine differences in biomechanical measures based on child and fall characteristics in reliable witnessed video-recorded falls involving children. The results of this study will serve as preliminary data for an on-going larger study with the …


Exploring The Community Impact Of Community-University Partnerships, Stacey D. Muse Jan 2018

Exploring The Community Impact Of Community-University Partnerships, Stacey D. Muse

Electronic Theses and Dissertations

The field and movement of community engagement in higher education is one way for institutions of higher education to fulfill the public good mission. Community engagement practices have shifted to valuing democratically engaged partnerships between the community and campus (Saltmarsh, Hartley, & Clayton, 2009). However, the research on community engagement reveals a lack of understanding of community voice and perspective on if and how community-campus partnerships make a difference for community-based organizations partnered with institutions of higher education. This embedded case study begins to fill these gaps in the literature by examining the voice and perspective of community-based organizations partnered …


Understanding Why Women Stay: Examining Persistence Factors Of Women Majoring In Science And Technology Programs In Public Ethiopian Universities Using A Mixed Methods Design, Meseret Hailu Jan 2018

Understanding Why Women Stay: Examining Persistence Factors Of Women Majoring In Science And Technology Programs In Public Ethiopian Universities Using A Mixed Methods Design, Meseret Hailu

Electronic Theses and Dissertations

Amongst African nations, Ethiopia is a unique case in many respects. The country has the second largest population on the continent, is currently experiencing an economic boom, and is a relatively stable nation in the geopolitically volatile "Horn of Africa" region. In the past two decades, the higher education sector in Ethiopia has experienced rapid growth, as evidenced by an increase in both student enrollment and the number of universities. Amongst the various types of higher education institutions, public universities are especially important because they receive the greatest financial support from the Ministry of Education. Moreover, science and technology programs …


Funds Of Knowledge And The College Success Of First-Generation Students, Low-Income Students, And Students Of Color: A Transformative Mixed Methods Study, Delma Margot Ramos Jan 2018

Funds Of Knowledge And The College Success Of First-Generation Students, Low-Income Students, And Students Of Color: A Transformative Mixed Methods Study, Delma Margot Ramos

Electronic Theses and Dissertations

Increases in college enrollment have led to assessments of college success. These assessments consistently reveal disparities between students from historically underserved communities and students from the majority. Specifically, first-generation to college students, low-income students, and students of color continue to experience unequitable success in college. In response to these concerns, the scholarly community engages in research that expands our understanding of college success of these students and offers solutions to bolster their success. Nonetheless, much of this work engages a deficit oriented approach that centers attention on the resources that historically underrepresented communities do not possess and attributes lower college …


Soil Morphological, Physical, And Chemical Parameters Affecting Longleaf Pine (Pinus Palustris) Site Quality And Ecosystem Restoration Potential In East Texas, Ryan Svehla, Kenneth W. Farrish Dec 2017

Soil Morphological, Physical, And Chemical Parameters Affecting Longleaf Pine (Pinus Palustris) Site Quality And Ecosystem Restoration Potential In East Texas, Ryan Svehla, Kenneth W. Farrish

Electronic Theses and Dissertations

There has been a large decline in coverage of longleaf pine (Pinus palustris Mill.) within its range in the southeastern United States since the time of European settlement. Due to this decline, interest has developed in the re-establishment of this species on suitable sites. However, many attempts have been unsuccessful in re-establishment, likely in part due to the lack of emphasis on selection of suitable soils. Historically, longleaf pine was found on soils with a wide range of soil properties, including higher quality soils, due to frequent fires which kept many competing species suppressed. Decline in longleaf pine coverage …


Estimating Density And Residency Of Bottlenose Dolphins (Tursiops Truncatus) In Three Estuarine Sites In South Carolina, Jessica Nicole Conway Dec 2017

Estimating Density And Residency Of Bottlenose Dolphins (Tursiops Truncatus) In Three Estuarine Sites In South Carolina, Jessica Nicole Conway

Electronic Theses and Dissertations

Of the three estuarine bottlenose dolphin stocks in South Carolina, two are considered data insufficient, with no minimum population estimate or assigned potential biological removal value. Additionally, the Northern Georgia Southern South Carolina Estuarine System (NGSSCES) stock’s boundaries are based on sighting data that do not extend to the full area encompassed by the boundary lines. In areas where stock boundaries are not clearly defined and data is insufficient for traditional methods of estimating abundance, density may provide insight into local distributions and serve as a proxy for actual abundance. Photo-identification surveys were conducted in three sites, representative of the …


Habitat Use Of Blacktip Sharks (Carcharhinus Limbatus) At Fishing Piers, Kelsey L. Spencer Dec 2017

Habitat Use Of Blacktip Sharks (Carcharhinus Limbatus) At Fishing Piers, Kelsey L. Spencer

Electronic Theses and Dissertations

Blacktip sharks (Carcharhinus limbatus) can be observed near fishing piers throughout the summer along the northeast coast of South Carolina. These piers attract and support a wide variety of potential prey and sharks are able to forage on fishers’ discards with minimal energetic cost. I tagged 12 blacktip sharks with acoustic transmitters, monitored piers with acoustic receivers, and conducted pier-creel surveys to determine the habitat use of blacktip sharks at fishing piers, factors that influenced residence time and presence/absence at piers, and any cyclical patterns in visits to piers. Data were analyzed with pier association indices (PAI), mixed models, and …