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From Case Study As Symptom To Case Study As Sinthome: Engaging Lacan And Irigaray On "Thinking In Cases" As Psychoanalytic Pedagogy, Erica Freeman

Electronic Theses and Dissertations

This dissertation accomplishes two goals. First, this dissertation articulates a Lacanian account of the epistemological and historical presuppositions of the psychoanalytic case study genre, while engaging reflexively with extant Foucauldian scholarship on this genre as well as feminist psychoanalyst Luce Irigaray’s criticisms of Lacan. Irigaray’s critique is engaged in order to tarry with its implications for a Lacanian approach to the psychoanalytic case study genre. Second, this dissertation critically examines the significance of Lacan’s (re)reading, in Seminar V, of Joan Riviere’s (1929) “Womanliness as Masquerade” in the midst of his oral teachings on the psychoanalytic concepts of castration and …

Evaluating The Biological Effects And Safety Of Exposure To Low, Putatively Safe Concentrations Of The Common Pesticide Chlorpyrifos Using An Anuran Model, Sara Mcclelland

Electronic Theses and Dissertations

In the US, over 1.1 billion pounds of pesticides are applied annually. Unfortunately, pesticides contaminate natural habitats affecting animal health. Chlorpyrifos (CPF) is an organophosphorous insecticide that contaminates surface waters. Few studies have assessed the impacts of CPF at low, ecologically realistic doses. I aimed to test the effects of low dose CPF exposures on biological parameters including body morphology, hormone levels, and brain development in Northern Leopard Frogs (Lithobates pipiens), a common vertebrate model. To determine if CPF exposure has direct impacts or indirectly impacts animals through the disruption of the food web, I examined CPF exposure …

Aphasia Friendly Medication Instructions: Effects On Comprehension In Persons With And Without Aphasia, Anna Saylor

Electronic Theses and Dissertations

Accessible health information supports people to understand and manage chronic medical conditions and is frequently presented via text. Comprehension of written health information becomes more difficult for people with language impairments, such as aphasia. Nine people with aphasia (PWA) and nine people without aphasia (PWoA), participated in this study. Each participant reviewed two unmodified medication instructions and two modified medication instructions using aphasia-friendly principles, then answered eight multiple choice questions and provided their preferences. Results showed that PWA demonstrated improved comprehension given modifications, but PWoA’s comprehension did not improve with modifications. Group comparison in the modified condition demonstrated that PWoA …

The Effect Of Teacher-Child Interaction Training On Children Who Are Exhibiting Disruptive Behaviors Within The Classroom Setting, Jaclynn Susan Stankus

Electronic Theses and Dissertations

Teacher-Child Interaction Training (TCIT) is an adaption of the evidenced-based treatment of Parent-Child Interaction Therapy (PCIT). The TCIT intervention is used with students, typically in a preschool setting, who are exhibiting disruptive behaviors within the classroom. Teacher-Child Interaction Training improves the teacher-child relationship, while also training teachers to use effective and consistent consequence strategies. The large research base behind PCIT and the growing empirical base for TCIT provides evidence that this model would be an effective early intervention treatment for young children exhibiting disruptive behaviors in their school settings.

The success of Teacher-Child Interaction Training (TCIT) with the general preschool …

The Banality Of The Social: A Philosophy Of Communication Of Social Media Influencer Marketing, Kati Sudnick

Electronic Theses and Dissertations

This project engages in a philosophy of communication approach in order to understand the role of social media influencer marketing within a historical moment defined via Hannah Arendt’s understanding of the social. Social media influencer marketing emerges as a new form of celebrity endorsement in which those finding fame on the Internet engage in word-of-mouth marketing for brands and organizations on their own personal social media pages, blurring the line between organic and sponsored content. According to Arnett (2010), philosophy of communication acts as a background road map for understanding foreground public action. Utilizing a myriad of metaphorical coordinates as …

Listening To The Voices Of International Undergraduates Regarding Their Perceptions Of Engagement And Their Strategies To Achieve Academic Success, Gulcan Tokluoglu

Electronic Theses and Dissertations

While international students greatly influence globalization with their diverse cultural backgrounds, they often encounter issues when adapting to a new academic, social, and cultural setting. The goal of this research question was twofold in nature in that it sought to not only explore the adjustment experiences of participants but also be able to see what resources and practices were found helpful and needed to be expanded upon in order to provide ways of redressing inequitable practices and contributing to pedagogical change to promote engagement and success of international undergraduate students. A thorough analysis of in-depth interviews considered both upstream and …

Effects Of Hands-On Experiences On Student Achievement, Interest, And Attitude In Chemistry, Donna Gretchenn Adkins

Electronic Theses and Dissertations

This study examined the effect of hands-on experiences on student achievement, interest, and attitude in chemistry. The researcher gathered data from 82 students enrolled in an East Texas high school chemistry course for the 2019-2020 school year. Historical data from five-unit tests were used to assess differences in mean achievement scores between test items aligned with hands-on laboratory experiences and test items aligned with computer-simulated experiences. An independent t-test and a paired t-test were used to statistically evaluate the data. The independent t-test showed no statistically significant difference. However, the paired t-test did indicate a statistically significant difference. To assess …

A Bioethical Paradigm For Enhanced, Post Or Transhumans In Medicine And Biological Research, Roderick Williams

Electronic Theses and Dissertations

In this dissertation the question addressed is the ethical protocol that should be used when enhanced, post or transhumans present themselves as patients to hospitals, or as subjects for scientific research. With the advent of the birth of four children who were genetically engineered in China to be resistant to HIV, I contend that transhumans are already here, and the prevailing Western paradigm of principlism, while good, is not adequate to the task. I explore the basic religious argument that can be used against or in favor of what I call human-directed human evolution. I show how the fears of …

Exploring Visual Attention Patterns Of Adults With Reported Adhd, Without Adhd, And Those With Malingering Adhd Symptoms, Roselia Juan

Electronic Theses and Dissertations

Noncredible performance and the intentional faking of symptoms during psychological evaluations have been observed in those seeking to obtain personal benefits. Cognitive deficits, such as impairments in attention are common in mental health settings and many seek an evaluation to rule out an attention-deficit/hyperactivity disorder. Previous literature establishes a base rate for malingering to be between 22-47% in adult ADHD evaluations (Sullivan, 2007; Suhr et al., 2008; Marshall et al., 2010). However, those faking or exaggerating ADHD can go unnoticed on self-report measures. There are limited studies that have identified methods that can specifically discriminate true ADHD from malingered ADHD. …

20th And 21st Century Sea-Level Variability In Winyah Bay, Sc, Madison Schemery Fink

Electronic Theses and Dissertations

No abstract provided.

Without Words: Relational Neuropsychology And Creative Arts Therapies With People Managing Aphasia, Autumn Marie Chilcote

Electronic Theses and Dissertations

Aphasia describes the broad experience of disrupted language production or comprehension acquired after structural changes in the brain. These changes, usually associated with stroke, tumor, or cortical degeneration, are often co-occurring with other symptoms, such as emotional dysregulation, partial paralysis, and difficult social, occupational, and community relationships. Common approaches to research and rehabilitation with persons managing aphasia highlight conversation and semantic retrieval, with a lack in literature considering the diversity of symptoms and responses. Questions arise as to the ways that psychotherapies, typically language- centered, can be adapted to collaborative, low-verbal approaches that attend to the range of individual symptoms …

The Influence Of Environmental Variables On The Height Growth Of Loblolly Pine (Pinus Taeda) In The Western Gulf, Osakpamwan Edo-Iyasere

Electronic Theses and Dissertations

Understanding the effects of environmental factors on stand growth is important in optimizing forest management plans. This study investigated the effects of soil and climate factors on the height growth (site index) of loblolly pine (Pinus Taeda L.) using data collected from permanent plots established in intensively-managed plantations across East Texas and Western Louisiana. The Chapman-Richards model was selected as the base model to describe the height-age relationships and important soil and climate variables were incorporated into the models as model parameter coefficient adjustors. Our results showed that the most important factors for predicting site index were nitrogen …

Isotopic Analysis Of Human Migration Among The Ancient Maya Of Ambergris Caye, Belize, Rachel L. Smith

Electronic Theses and Dissertations

This thesis uses the isotopic composition of tooth enamel from two Maya sites on Ambergris Caye Belize, to identify basic patterns of population movement among the Classic period Maya. Three individuals from San Juan and ten individuals from Chac Balam will shed light on the origin of individuals buried at the sites, including those with nonlocal grave goods. Strontium and oxygen isotope values provide new information on Maya coastal populations and suggest that at least one individual with a distinct body position had a nonlocal origin. Carbon isotope values reveal a childhood diet related to, but not the same as, …

Predictors Of Urban Homeless Rates., Andrew John Bates

Electronic Theses and Dissertations

This dissertation analyzes the differences among homeless rates in urban and suburban “continuums of care” (service areas for homelessness in the United States) over the period of 2014-2018. The purpose is to determine which variables are useful to predict the rates of two definitions of homelessness: the more extreme “Category One” homelessness as defined by the U.S. Department of Housing and Urban Development (HUD): those unsheltered or living in homeless shelters; and the broader Department of Education definition of homelessness: families with children that are homeless, including those in Category One but also those living in hotels, staying temporarily with …

Marginal Methods And Software For Clustered Data With Cluster- And Group-Size Informativeness., Mary Elizabeth Gregg

Electronic Theses and Dissertations

Clustered data result when observations have some natural organizational association. In such data, cluster size is defined as the number of observations belonging to a cluster. A phenomenon termed informative cluster size (ICS) occurs when observation outcomes vary in a systematic way related to the cluster size. An additional form of informativeness, termed informative within-cluster group size (IWCGS), arises when the distribution of group-defining categorical covariates within clusters similarly carries information related to outcomes. Standard methods for the marginal analysis of clustered data can produce biased estimates and inference when data have informativeness. A reweighting methodology has been developed that …

N-Acetyltranserase 2 (Nat2) Genotype Polymorphism In Cryopreserved Human Hepatocytes And Chinese Hamster Ovary (Cho) Cells., Mariam Refaat Zaky Habil

Electronic Theses and Dissertations

Arylamine N-acetyltransferases, NAT1 and NAT2, catalyze the detoxification and/or activation of drugs and aromatic amine carcinogens. Single nucleotide polymorphisms or SNPs result in different human NAT2 genotypes thus dividing the population into rapid, intermediate, and slow acetylators. We hypothesize allelic variants of NAT2 genotype will decrease levels of N-acetylation, cytotoxicity, oxidative stress, DNA adduct formation, and mutagenesis compared to the reference allele NAT2*4. Cryopreserved human hepatocytes expressing different NAT2 genotypes and NER-deficient Chinese hamster ovary (CHO) cells transfected with human CYP1A2 and human NAT2*4, NAT2*5B or NAT2*7B have been used to investigate N-acetylation of different xenobiotics. In …

Modulation Of Inflammatory Pathway By Inflammatory Inhibitor Jsh-23 Mitigates Diabetic Retinopathy., Rubens Petit Homme

Electronic Theses and Dissertations

Diabetic retinopathy (DR) is the most common microvascular complication of diabetes mellitus (DM). Its pathology is consisted of the breakdown of the blood-retinal barrier (BRB), particularly the inner blood-retinal barrier (iBRB). The exact mechanism that leads to the iBRB impairment and the development of DR has not been elucidated yet. However, chronic inflammation that is hallmark of the type I DM has recently become a key focus in DR study. Hyperglycemia causes dysregulation of nuclear factor-kappa B (NF-kB); and its constant activation increases the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and intercellular adhesion molecule-1 (ICAM-1) in the …

Therapeutic Rupture Repair In Treatment Of Military Adolescents., Brent Anthony Luebcke

Electronic Theses and Dissertations

Ruptures in the therapeutic alliance have shown to be a significant predictor of therapy outcomes, with non-repaired ruptures resulting in increased dropout rates of therapy, and repaired ruptures resulting in positive therapy outcomes. This study investigated the impact of alliance ruptures on outcomes of therapy among youth and adolescents, with a specific focus on military youth and adolescents. A sample of 5,640 military adolescents who were treated by 101 therapists were selected for analysis based on inclusion criteria of: a) being aged 13 to 19 years old; and b) attending more than one session of therapy. Each session, clients completed …

Mechanisms Of Chromate-Induced Suppression Of Rad51: A One Environmental Health Approach., Rachel M. Speer

Electronic Theses and Dissertations

Lung cancer is the leading cause of cancer death. Lung cancer is commonly associated with smoking, however, 1 in 5 women and 1 in 12 men who develop lung cancer are never-smokers. Environmental exposures, therefore, account for a significant portion of lung cancer cases. Hexavalent chromium [Cr(VI)] is a global environmental contaminant and known human lung carcinogen. Cr(VI) and other carcinogenic metals induce chromosome instability, an early event in lung cancer. Structural chromosome instability arises in part due to failed DNA repair. Particulate Cr(VI), the most potent form of Cr(VI), induces DNA double strand breaks and inhibits the high-fidelity DNA …

Genes Involved In Nitrogen Assimilation In Ustilago Maydis., Sunita Khanal

Electronic Theses and Dissertations

U. maydis can utilize nitrate as a source of nitrogen from its environment, a process requiring a nitrate transporter to bring the nitrate inside the cell. This is followed by a two-step reduction of nitrate to ammonium. At first, nitrate reductase reduces nitrate into nitrite; in the second reaction, nitrite is reduced to ammonium by nitrite reductase. The goal of the study was to identify the nitrate transporter and nitrite reductase genes in U. maydis and characterize them based on their role in mating and virulence. The genes um03848 and um03849 were identified bioinformatically as encoding, respectively, the nitrite reductase …

Moral Distress And Moral Residue Among Nurses Working In The Surgical Intensive Care Unit: A Descriptive Qualitative Approach., Adam Tyler Booth

Electronic Theses and Dissertations

Introduction: Approximately one in five Americans will die in the intensive care unit (ICU). Nurses spend more time with chronically ill and end-of-life patients than any other healthcare professional, and may perceive some actions in the ICU as immoral. Moral distress is defined as knowing the right course of action to take but being hindered by institutional constraints. Development of the Moral Distress Scale-Revised revealed that 31% of ICU nurses left a prior position or considered leaving their current nursing job because of moral distress. The purpose of this descriptive qualitative study is to explore surgical ICU (SICU) nurses’ perceptions …

Comparative Secretomics And Functional Analysis Of Effectors Utilized By The Microbotryum Genus Of Anther-Smut Fungal Pathogens, And Their Role In Host-Specificity., William Christopher Beckerson

Electronic Theses and Dissertations

Understanding how pathogens evolve in response to changes in their host is paramount to combating the spread of emergent strains of disease. This is particularly true for plant pathogens that cause billions of dollars of damages to crops globally, every year. Understanding the molecular interactions between pathogens and their hosts therefore sheds light on the coevolutionary arms race that can result in host-specificity and host-shifts in plant pathogens. This research approaches the question of how fungal pathogens interact with their plant hosts utilizing both unique and shared arsenals of secreted proteins (SPs) during infection, and addresses the question of whether …

Gun Ownership As An Expression Of Whiteness And Masculinity., Michael Daugherty

Electronic Theses and Dissertations

Public discourse on the topic of gun ownership in the U.S. is polarized, with the debate framed as a binary between unquestioned gun rights versus a complete ban. Gun ownership can have grave consequences: guns are used to commit acts of violence and suicide. Interviews with white male gun owners explore the influence of white backlash, masculinity, and racial identity development in their decisions to own guns. This project explores the extent these reasons are related to race on the part of white males, starting with these two questions: How much does race play a factor in the action and …

Tissue-Resident Myeloid-Derived Suppressor Cells Modulate Immune Homeostasis In Healthy Adipose., Katlin Brooke Stivers

Electronic Theses and Dissertations

Our goal with this study was to gain insight into the homeostatic immune cell network in healthy adipose tissue. Specifically, we sought to determine if the immature myeloid cells found in healthy and inflamed adipose were, in fact, tissue-resident myeloid-derived suppressor cells (MDSCs). Using various in vitro and in vivo methods, we have uncovered a population of CD11b^Hi Ly6C^Hi Ly6G^- MDSCs resident in healthy adipose tissue. To the best of our knowledge this is the first time that these cells have been investigated and described in healthy adipose tissue. Systemic MDSC depletion lead to the accumulation of …

Plasmodium Impairs Antibacterial Innate Immunity To Systemic Infections In Part Through Hemozoin-Bound Bioactive Molecules., Christopher Lynn Harding

Electronic Theses and Dissertations

Despite efforts to decrease the global health burden of malaria, infections with Plasmodium species continue to cause over 200 million episodes of malaria each year which resulted in 405,000 deaths in 2018 [1]. One complication of malaria is increased susceptibility to invasive bacterial infections. Plasmodium infections impair host immunity to non-Typhoid Salmonella (NTS) through activities of heme oxygenase I (HO-I) )-induced release of immature granulocytes and myeloid cell-derived IL-10. Yet, it is not known if these mechanisms are specific to NTS. We show here, that Plasmodium yoelii 17XNL (Py) infected mice had impaired clearance of systemic Listeria monocytogenes (Lm) during …

The Nigerian-American Immigration Experience: Overcoming Adversity Through Resilence., K. Chinwe Idigo

Electronic Theses and Dissertations

Nigerian-Americans are a fast-growing population in the United States, when compared to other immigrant groups. Despite growing numbers there is limited empirical research examining pathways that facilitate success among this immigrant population. This study addresses the dearth in literature by proposing and testing a modified ABCX model of family resilience among Nigerian-Americans. It is hypothesized that similar to other immigrant, and racial/ethnic minority groups in the United States, NigerianAmericans employ protective factors such as ethnic identity and resilience to buffer the effects of acculturative stress and perceived discrimination on well-being and psychological distress. Regression analyses suggest some consistency with the …

Application Of Machine Learning Technologies For Detection Of Proximal Lesions In Intraoral Digital Images: In Vitro Study., Rohit Vadlamani

Electronic Theses and Dissertations

Background: Interpretation of bitewing radiographs is influenced by factors such as acquisition parameters (e.g. exposure, type of sensor), clinical technique, visualization (e.g. monitor type and calibration) and the observer (e.g. experience and fatigue bias). We hypothesized that the use of artificial intelligence (AI) will reduce visualization and observer factor in bitewing interpretation and improve diagnostic accuracy. Objective: The purpose of the present study was to evaluate the use of AI in the form of a machine-learning algorithm to detect and quantify proximal lesions compared with human trained observers. Methods: 16,000 anonymized, digital bitewings of patients were hand searched and non-bitewing, …

Identification And Structural Characterization Functional Motifs In The Porphyromonas Gingivalis Mfa1 Short Fimbria., Mohammad K. Roky

Electronic Theses and Dissertations

Porphyromonas gingivalis is a causative agent of periodontal disease, initially colonizes the oral cavity by adhering to commensal streptococci. Adherence requires the interaction of the minor fimbrial protein (Mfa1) of P. gingivalis with streptococcal antigen I/II (Ag I/II). A peptide derived from Ag I/II peptide has been well characterized and shown to significantly reduce P. gingivalis colonization and bone loss in vivo, suggesting that this interaction represents a potential target for therapeutic intervention. However, the functional motifs of Mfa1 involved in the interaction with Ag I/II remain uncharacterized. A series of N- and C-terminal peptide fragments of Mfa1 were …

Analysis Of Twenty-First Century Zines., Anna Blake

Electronic Theses and Dissertations

This thesis is an analysis of twenty-first century zines as markedly different from their predecessors. The twenty-first century zine is often framed as a continuation of the punk zines from the late twentieth century, this thesis disagrees and argues for the classification of the twenty-first century zine as a unique form of culture that has evolved from the punk zines of the 1980s and 90s. The thesis is divided into five chapters in which the twenty-first century zine is analyzed using specific examples. Chapter one begins with an introduction of the zine, defining the object based on its social consequences …

Fatalism As A Cultural Influence On Correlates Of Anxiety And Worry In Latino/A Adolescents., Judy Mier-Chairez

Electronic Theses and Dissertations

Evidence that Latino/as in the United States experience lower rates of anxiety disorders as compared to the non-Latino/a White population has not yet led to the identification of the sources of these differences. Higher rates of anxiety disorders among more acculturated Latino/a individuals compared to those lower in acculturation suggest there are influential cultural variables relevant to anxiety, specifically that there is a loss of a protective Latino/a cultural factor in the acculturation process. Fatalism, an often-cited Latino/a cultural characteristic, emerges as an intriguing candidate for exploration in relation to anxiety due to the shared elements of future orientation and …