Digital Commons Network^™

Role Of Cellular Proteins In The Regulation Of Herpes Simplex Virus Type 1 Gene Expression And Dna Replication, Joseph R. Heath

Electronic Theses and Dissertations

Herpes simplex virus type 1 (HSV-1) is a ubiquitous human pathogen that infects the majority of the human population. To facilitate infection, this virus relies on a combination of host and viral factors. Previous studies have revealed a number of host proteins that associate with the HSV-1 genome throughout infection but their putative role(s) in this process remain undefined. This study aims to examine two such proteins to determine their contributions to HSV-1 gene expression and DNA replication. The first of these factors is Ints3, a subunit of the Integrator complex. This protein complex functions in transcription regulation, and Ints3 …

Investigating The Multiple Enzyme Complex In The Carotenoid Biosynthesis Pathway, Mercy Mormor

Electronic Theses and Dissertations

In nature, plant carotenoids are 40-carbon isoprenoids with polyene chains that may have double bonds. They are vital components of all photosynthetic organisms, playing several roles in the plant cell, including photosynthesis, pigmentation, phytohormone synthesis, signaling and photoprotection. In this study, we investigated protein-protein interactions among key enzymes involved in the carotenoid biosynthesis pathway using the Bimolecular Fluorescent Complementation (BiFC) assay. Our results revealed several interactions that suggest a coordinated regulation of enzymatic activity within this pathway, highlighting potential regulatory complexes that influence carotenoid production. The study also highlights the pivotal role of Zeta-Carotene Isomerase (Z-ISO) as a key regulatory …

"No One Leaves For Free": A Media Analysis Of The Lived Experiences And Cumulative Impacts Of The Flint Water Crisis., Jordan Leigh Gatewood

Electronic Theses and Dissertations

In April 2014, the city of Flint, Michigan changed their municipal water source from Lake Huron to the Flint River. The effects of this change have been felt far and wide as news broke across the nation that this water was contaminated with lead and residents of Flint were getting sick. This research analyzes 170 news articles from three local and three national news outlets over a 10-year span, 2014 to 2024, to determine how community voice is presented in news media to portray the lived experiences and cumulative impacts of the Flint Water Crisis. Applying a Critical Environmental Justice …

Exploring Factors Influencing Care And Outcome Among Stroke Patients In Tennessee, Omodele Agbejimi

Electronic Theses and Dissertations

Introduction: Stroke is the fifth leading cause of death in Tennessee. Socioeconomic variables influence the delivery of stroke treatment and its outcomes. Despite advances in acute stroke care, the burden of stroke keeps increasing. This study aimed to explore literature on factors contributing to stroke care and outcomes in the U.S., assess the determinants of stroke patients’ outcomes, and examine the geographical disparities in stroke hospitalization and stroke death rate and their association with stroke care accessibility in Tennessee.

Methods: A scoping review was conducted using socio-ecological models to explore literature on factors contributing to stroke care and outcomes. A …

Isolation And Characterization Of Siderophore(S) From Pseudomonas Mosselii, Casey J. Stophel

Electronic Theses and Dissertations

Iron is essential for growth of most microorganisms. It functions as an important cofactor in many important biological processes. However, iron found in soil is rendered insoluble and unavailable to microorganisms for use. To overcome this, many bacterial species produce siderophores, a small organic molecule that has high affinity for iron. Siderophores allow for bacterial cells to obtain otherwise insoluble iron. Pseudomonas mosselii, a Gram negative bacterium, was isolated from a local soil sample. P. mosselii was found to produce siderophore(s) under iron restricted environment, however, they have not been characterized. Therefore, it was of interest to isolate, purify and …

The Intersection Of Appalachian Identity And Gambling Behavior, Noah S. Anderson

Electronic Theses and Dissertations

This study examined the relation between Appalachian identity and gambling behavior among students in central Appalachia (n = 395). One-way ANOVAs revealed no significant differences in engagement, F(2, 392) = 0.65, p = .523, or severity, F(2, 392) = 0.33, p = .718, across identification groups. Moderated regression showed that identity did not significantly moderate the engagement–severity relation (B = 0.073, p = .099), though engagement itself was a strong predictor of harm (B = 0.696, p < .001, R² = .521). Negative affect predicted both engagement (B = 0.074, p = .001) and severity (B = 0.069, p = .001), while identity remained non-significant. Logistic regression found that identity predicted gambling engagement (Exp(B) = 1.18, p = .034) only when controlling for severity. These findings relay the importance of empirical efforts in Appalachia and suggest that Appalachian identity may not be an independent risk factor in gambling behavior.

Drivers And Consequences Of Changes In Nectar Microbiome Composition Across Spatial And Biological Scales, Daniel A. Barker

Electronic Theses and Dissertations

Microbial communities inhabiting floral nectar, known as the nectar microbiome, are important mediators of plant-pollinator interactions. However, the ecological and environmental factors that shape the composition of these microbial communities remain poorly understood. While previous studies have examined the effects of a few microbial groups, typically independent of one another, on one plant or pollinator species, this dissertation takes a wide-scale approach to explore how abiotic conditions and biotic interaction’s structure microbial communities within floral nectar. Furthermore, I also quantify how variation in microbial richness and identity influences pollinator behavior and plant reproductive success.

This dissertation shows that microbial abundance …

The Effects Of Off-Season Evidence-Based Training Block Periodization Program On The Performance Of Soccer Athletes In A Di School: An Exploratory Study, Ibrahim F. Almughathawi

Electronic Theses and Dissertations

The investigators explored the effects of a two-year evidence-based block periodization strength training program on performance outcomes in NCAA Division I male soccer athletes. The investigators aimed to examine longitudinal changes in body composition, explosive strength, and match-play physical demands, as well as the associations between field-based performance assessment and GPS-derived metrics. Using a retrospective design, data were drawn from a research data repository for athletes who participated in a long-term sport science monitoring program under the same head coach and training conditions. Performance measures included vertical jump assessments (static and counter movement jumps under bodyweight and external load), isometric …

Diagenesis And Controls On Porosity And Permeability In The Upper San Andres Formation Of West Texas, Jack Butcher

Electronic Theses and Dissertations

West Texas reservoirs on the Central Basin Platform (CBP) are dominated by Permian-age carbonate deposits, significantly contributing to petroleum production. The Upper Permian-aged San Andres Formation, composed primarily of dolomite and limestone, is a prolific reservoir. This study assesses diagenetic influences on porosity and permeability within the San Andres Formation along the northern CBP. Two cores from the Monument 4-2 and Peterson 1 wells in West Texas were analyzed using core descriptions, thin section petrography, XRD, XRF, and MICP. Results indicate that dolomitization enhances porosity, with intercrystalline and moldic porosity being dominant, while late-stage cementation and compaction reduce permeability. XRD …

An Evaluation Of Key Components Of Natural Resource Camps, Undergraduate Persistence And Success In Natural Resources, Brandy Bishop

Electronic Theses and Dissertations

This study explores the key components that connect natural resource camps, undergraduate persistence, and overall success through gainful employment within the natural resource industry. The aim of this study was to assess early interest and attitudes towards natural resource career pathways and how education interventions shape students’ career outcomes thus leading to overall success. A longitudinal mixed method design was used combining Conservation Careers Camp survey data (n = 39) with institutional records for Forestry majors (n =655) in the Arthur Temple College of Forestry and Agriculture on the Stephen F. Austin State University campus. Quantitative data was analyzed through …

Perceived Leadership Behaviors And Workplace Motivation: The Predictive Role Of Generational Cohorts In The U.S. Construction Industry, Leslie D. Klinegardner

Electronic Theses and Dissertations

The purpose of this study was to examine the extent to which perceived leadership behaviors predicted workplace motivation among construction workers across generational cohorts in the Greater Houston, Texas area. Grounded in self-determination theory, the research explored how transformational, transactional, and passive-avoidant leadership behaviors predicted the satisfaction and frustration of psychological needs for autonomy, competence, and relatedness. The analysis also considered whether leadership behaviors and generational cohort served as significant predictors of workplace motivation outcomes. The study followed a quantitative, predictive, cross-sectional design using survey methodology. Data were collected using the Multifactor Leadership Questionnaire (MLQ) and the Basic Psychological Need …

Principal Self-Efficacy: A Qualitative Study, Vance E. Self

Electronic Theses and Dissertations

This qualitative study explored elementary principals’ perspectives on the importance of selfefficacy in relation to management responsibilities, instructional leadership, and moral leadership as they impact student achievement measured by the STAAR in a Central Texas school district. The research addressed the growing challenges principals face in high-accountability environments, focusing on how their beliefs in their leadership abilities affect school performance and student outcomes. The purpose was to examine principals’ views on selfefficacy across three domains and to consider implications for leadership preparation, district support, and policy. The study was grounded in a constructivist paradigm and employed a qualitative case study …

Electronic Health Record Downtime, Grace R. Baldauf

Electronic Theses and Dissertations

Electronic health record (EHR) downtime presents significant challenges to patient safety and care quality in acute care settings, particularly regarding timely medication administration. This project addressed the problem of late or absent medication doses during planned or unplanned EHR downtime. The investigator aimed to evaluate the effectiveness of a structured downtime plan in improving nurses’ ability to administer medications on time during periods of EHR unavailability. The investigator used a quantitative design to implement a downtime plan evaluation paradigm. Data were collected using retrospective chart reviews of medication administration records pre-implementation and postimplementation of the downtime plan. The sample included …

Performance Of The Two Sample Likelihood Ratio Test Under A Nested Dirichlet: A Simulation Study, Edwina Agyeman

Electronic Theses and Dissertations

Compositional data analysis (CoDA) addresses multivariate data constrained to a constant sum, such as proportions or percentages. Originating from early warnings regarding misinterpretation by Pearson (1897), the field was formalized by John Aitchison in 1986, whose foundational work remains highly influential. Over time, new modeling techniques and visualization tools have advanced the field, as noted by Greenacre et al. More recently, Turner et al. proposed an approach based on the Nested Dirichlet Distribution (NDD), which accommodates more flexible dependence structures than the standard Dirichlet model. This thesis builds on the methodology of Turner et al. Chapter 1 introduces the nature …

Leadership Emergence Among Black Urban Women Survivors Of Intimate Partner Violence: A Qualitative Exploration, Dawn H. Benton

Electronic Theses and Dissertations

This study proposed to identify leadership strategies that assisted intimate partner violence-impacted Black women in urban areas to become leaders in their homes and communities as perceived by mental health professionals. Nine mental health professionals and counselors from an Ohio urban area completed a questionnaire and a semi-structured interview to provide data about Black women in intimate partner violence-impacted relationships living in a metropolitan area in Ohio. Deprived of valuable leadership resources and gifts that the women can offer their families and communities, investigators omitted the women's plights in their studies. Four research questions framed this qualitative case study design …

Under The Legal Lens: Navigating Psychological Safety And Conflict For Black Women In Legal Support Roles, Chanel M. Bradden

Electronic Theses and Dissertations

The intersectional challenges of Black women in legal support roles are an overlooked phenomenon in organizational research. Despite diversity efforts in the legal profession, Black women face challenges due to gender, race, and professional status that impact their career advancement, as well as their mental and psychological well-being. As a result of experiencing the effects of racialized workplace dynamics and destructive leadership behaviors, Black women in legal support roles find resilience through self-protection strategies while working through the effects of intersecting forms of oppression in legal workspaces. This study addressed the lack of knowledge of the lived experiences of Black …

Enhancing Multi-Step Stock Price Forecasting With Social Media Sentiment And Engagement Metrics, Damilare Olaniyan

Electronic Theses and Dissertations

This thesis investigates whether social media sentiment can improve the accuracy of stock price prediction beyond traditional historical data. While financial markets have long relied on structured numerical indicators, the growing influence of public discourse on platforms like Twitter has introduced new opportunities for extracting market-relevant signals from unstructured text. The study focuses on four major technology firms and combines sentiment features derived from Twitter with historical stock prices in a hybrid machine learning framework. Engagement-weighted sentiment, linguistic complexity, and polarity intensity were extracted using natural language processing techniques and incorporated into classification and regression models. Results show that including …

Artists In The Alternative Genre: Communication Through Music, C. L. Noë

Electronic Theses and Dissertations

Musicians throughout time and genre have strived to connect with their audience through music, whether they are trying to communicate a story or their own unique style. Musicians in alternative rock genres are no different, and therefore, this thesis looks at three different bands and analyzes the ways they convey meaning through their music for their audiences. Starting with Green Day, in the American Idiot album, they communicate the inner turmoil of the characters through a rhythmic motif and the different ways it presents in the music. Next, Fall Out Boy communicates authenticity to their fans through lyrics, vocal style, …

Harlem’S Avenues For Agency: An Exploration Of Black Female Agency In Angelina Weld Grimké And Zora Neale Hurston’S Short Stories, Jessica Ellen Hartenbower

Electronic Theses and Dissertations

This thesis explores themes of Black female agency in selected short stories by Angelina Weld Grimké and Zora Neale Hurston. Pushing back against the belief that the Harlem Renaissaince was a movement solely for male artists, Grimké and Hurston write short stories that center Black women and their experiences. Through the avenues of bodily autonomy, the using or silencing of voice, the opportunity and ability to make choices, issues of justice, retribution, and vengeance, the holding of authority, and being empowered or disempowered, I examine the female characters’ exercising of their agency to varying degrees. I also discuss how religious …

Interactive Read-Alouds Of Translingual Texts As A Catalyst For Literacy Engagement Among Emergent Bilingual Elementary Students: A Case Study, Anna Handy

Electronic Theses and Dissertations

While the population of emergent bilingual students continues to increase in U.S. schools, the teaching force remains predominantly White and monolingual, with many educators underprepared in how to support emergent bilingual students’ literacy development or sustain their diverse linguistic practices. This is reflected in longstanding gaps in performance between monolingual and multilingual students on standardized assessments of reading. The purpose of this qualitative case study was to explore one possible approach to increase emergent bilingual students’ engagement during and response to literacy instruction: interactive read-alouds of children’s books that incorporate translanguaging. This study sought to describe and interpret how emergent …

A Ritual Of Institutions: The State Industrial School In Golden, Colorado And The Shaping Of American Youth, Cyndal Groskopf

Electronic Theses and Dissertations

This thesis investigates the Colorado State Industrial School as a ritualistic institution that influenced boys aged 7 to 19 through Americanization practices between 1881 and 1930. By employing primary documentation, drone imagery, and LiDAR technology, the study examines how cultural and physical activities, along with personal statements, described and maintained the ritualized nature among these incarcerated youth. The findings reveal how institutional routines and activities reinforced narratives of American identity, particularly in relation to themes of personal identity, conformity, and agency. These rituals played a crucial role in institutionalizing cultural ideals and shaping the identities of marginalized youth. The research …

Optimizing Option Market Clearing, Juan Andrés Malaver Alvarado

Electronic Theses and Dissertations

Modern options markets clear each strike in isolation, leaving cross-strike arbitrage unexploited. This thesis applies a payoff-dominant clearing mechanism to realized trades—roughly 2 000 Cboe VIX option executions from June–November 2016—after classifying each trade’s side and bundling by expiration. Three optimization formulations are tested: a fractional linear program (LP), a mixed-integer LP, and a pure integer program. On a 10-core laptop every bundle solves in < 0.5 s. The LP captures the greatest surplus, yet the integer models recover nearly as much while filling whole contracts and holding only modest margin. Results reveal persistent, albeit small, inefficiencies in executed trades and demonstrate that an integral cross-strike auction could operate in real time. The accompanying C/Gurobi code is modular and readily extendable to early-exercise options. Trade-level evidence thus supports redesigning exchange clearing to consider the complete option book.

Reading Interventions In The Modern Era: Reconceptualizing The Utility Of Video Games, Senaida Mehmedovic

Electronic Theses and Dissertations

Youth in the United States continue to have difficulty developing reading skills, with only 31% of fourth graders reading at a “proficient level” (NAEP Reading: National Average Scores, 2024). Youth struggling to develop reading skills often have reading anxiety (Chow et al., 2021; Martinez, 2019; Ramirez et al., 2019), which impacts their reading skill development even more (Mohammadpur & Ghafournia, 2015); the interwoven and cyclical relationship between reading anxiety and reading comprehension requires interventions to address these needs concurrently (Francis et al., 2019; Francis et al., 2021; Grills et al., 2012). The increased avoidance and paired aversion of reading-related tasks …

The Self That Practices Deeper Teaching: An Exploration Of Influences On Teacher Beliefs And Values, Kerstin L. Rowe

Electronic Theses and Dissertations

For decades, educators have called for “a fundamental redesign of the industrial-age classroom.” However, despite ongoing discourse around educational reform, the majority of teachers still use the industrial model of education while too few teachers implement deeper teaching practices which situate students as active learners in addressing complex, real-world challenges rather than being passive recipients of knowledge. Existing literature does not explore the influences upon the beliefs and values of teachers who create deeper learning experiences.

This qualitative study employs educational criticism and connoisseurship to illuminate the inner self of those who practice deeper teaching. Drawing on in-depth observations, interviews, …

Foldit Education Mode, Brett Schulz

Electronic Theses and Dissertations

Foldit education mode is a puzzle campaign within the protein folding video game Foldit. Education mode, initially designed as a classroom supplement for undergraduate biochemistry courses, has been expanded to provide a more comprehensive learning tool to players without a background in biochemistry. The edited and added levels teach players about protein biochemistry through playing puzzles designed to convey information and gameplay mechanics. The new Foldit education mode campaign features 49 levels grouped into 11 categories. The campaign has 6 new levels designed specifically for education mode and 4 levels adapted from the traditional Foldit campaign for use within education …

Exploring The Effects Of Africana Studies On Black Undergraduate Students: A Qualitative Case Study, Lanaya M. Butler

Electronic Theses and Dissertations

Particularly in the context of American K-12 schools, education has been manipulated to control—rather than liberate—students through the erasure and distortion of Black history, experiences, perspectives, and capabilities. Additionally, American schools prioritize memorization and obedience while failing to equip students with critical thinking skills. As a result, students are trained to become workers rather than innovators, worldbuilders, and change-makers. For nearly a century, Black educational critics have stated that these systems were designed to subjugate Black community members through dehumanization and enslavement of the mind. These critiques are foundational to the aims of Afrocentric education which posits the life experiences …

Computational Fluid Dynamics And Fluid Structure Interaction Modeling In Healthy Vertebral Arteries: A Comparative Study, Bryce Clinkenbeard

Electronic Theses and Dissertations

Cerebral perfusion is critical for maintaining proper brain function, with each cerebrovascular artery playing an integral role in the overall cerebrovascular system. When these arteries become damaged or develop plaque, cardiovascular disease (CVDs) such as atherosclerosis can arise, leading to conditions like arterial stenosis. While CVDs are most prevalent in older individuals, they are also observed in young adults, particularly those engaged in high-endurance occupations such as military service. Diagnosis and prediction of CVDs often rely on imaging modalities supported by computational fluid dynamics (CFD) which account for low resolution in fluid flow. CFD models assume rigid arterial walls, which …

Development Of An Embedded Iot Board For Real-Time Floor Estimation Of Autonomous Robots, Carter J. Sorensen

Electronic Theses and Dissertations

As service robots become more prevalent in multi-story environments such as hospitals, hotels, and laboratories, accurate floor-level detection is critical to ensuring operational reliability. Consider a robot tasked with delivering medical samples in a multi-story laboratory. Without accurate feedback, a robot exiting on the wrong floor could introduce delays, disrupt workflows, or compromise sample integrity. Internet of Things (IoT) technologies offer a way to address these risks by providing real-time error detection and corrective capability. However, current IoT-based floor estimation systems often require invasive modifications to building infrastructure—particularly elevator control panels. These approaches introduce challenges related to cost, liability, backward …

“Eyes Can Be Blinded”: A Narratological Analysis Of Focalization In Sarah J. Maas’S A Court Of Thorns And Roses And A Court Of Silver Flames, Georga Mae Feek

Electronic Theses and Dissertations

This thesis explores the complex relationship between Feyre and Nesta, two prominent characters in Sarah J. Maas’s A Court of Thorns and Roses (ACOTAR) and A Court of Silver Flames (ACOSF). My analysis uses narratological concepts from three significant scholars in narrative theory: Gérard Genette, Shlomith Rimmon-Kenan, and Mieke Bal. I begin with a theoretical synthesis of narration and focalization and outline the various categories of types of narrators and focalizers. Then, I analyze Feyre’s focalization in ACOTAR and Nesta’s focalization in ACOSF. Through this process, I have developed rich character studies of Feyre and Nesta. My investigation of the …

Pilgrimage, Trade And Empire: A Gis Investigation Of Pre-Hispanic Roads In The Ocoña And Chorunga Valleys Of Peru, Geri Evilla

Electronic Theses and Dissertations

This research examines Inca imperial expansion into the Ocoña and Chorunga Valleys, through an investigation of precolonial roads and trails. It focuses on the Middle to Late Horizons (700 BCE-1534 CE), with specific attention to the last 100 years, when the region was occupied by the Inca state and experienced a rapid increase in population and architectural development. Data collected in excavations, and pedestrian, and drone surveys were used in geographic information systems, to map pre-Hispanic road systems. A combination of Least Cost Path and viewshed analyses were used to investigate land use patterns and tie this region into the …