Digital Commons Network^™

Extracellular Vesicles And Lipid Flippase Regulators In C. Elegans, Lauren Pitts

Electronic Theses and Dissertations

Extracellular vesicles (EVs) are membrane derived organelles released by all cell types and carry a vast array of cargos that can influence communication, development, and disease. One type of EV, known as microvesicles, form by budding directly from the plasma membrane in a process known as ectocytosis, however the mechanisms that govern this process are poorly understood. In C. elegans, the P4-ATPase, TAT-5, along with its activator, PAD-1, inhibit EV release from the plasma membrane by inhibiting phosphatidylethanolamine (PE) exposure on the outer leaflet of the plasma membrane. We identified 3 key domains of PAD-1 that are required to inhibit …

Economic Theology And The Death Of God In The Context Of The Crisis Of Neoliberalism, Jared A. Lacy

Electronic Theses and Dissertations

In light of the ongoing political and economic crises in the twenty-first century, this study aims to apply the discourse of political theology, alongside Nietzsche’s concept of the death of God to an understanding of neoliberalism and the problems it faces on a global level. However, because of the centrality of sovereignty in political theological discourse and the view of neoliberalism as diffusing sovereignty in favor of an ordered system, I attempt to further develop an offshoot discourse of political theology referred to as economic theology. This discourse allows a theological signature of power to be traced through the history …

Critical Experiences Of Being Humbled In Psychotherapy Training: An Interpretative Phenomenological Analysis, Mackenzie White Jessen

Electronic Theses and Dissertations

Therapists’ cultural humility has shown promise for being a “trait like” quality that improves psychotherapy treatment for marginalized populations (Hook et al., 2016, Owen et al., 2016). However, researchers have emphasized that it is important to establish whether cultural humility can be fostered or developed through training (Davis et al., 2016). The purpose of this study was to understand the phenomenon of trainees being humbled in session during graduate school training and its potential relationship to trainee development. This is the first study to specifically examine the experience of being humbled by clients in session or that explores the potential …

Outdoor Early Intervention Services: Current Practices And Future Directions, Tiffany Lee

Electronic Theses and Dissertations

Outdoor play is a crucial in supporting child development, resiliency, social skills, creative thinking, adaptability, family growth, and family engagement. Unfortunately, children are spending less time outside because of technology, parent fears, and other factors. Parents who have a child with a disability have even more challenges when it comes to playing outside. Thus, children with disabilities are spending even less time in outdoor environments. Early Intervention (EI) is a program that is designed for infants and toddlers between the ages of zero to three that have developmental delays and/or disabilities. EI uses a family-center approach in natural environments to …

Restorative Justice & A Dean Of Students: An Auto-Criticism Of The Role Of Care In School Discipline In A Poverty Impacted Public High School, Alicia D. Vasquez

Electronic Theses and Dissertations

This qualitative study is an auto-criticism, an approach that allows researchers to study themselves. This emergent methodology is derived from educational criticism and connoisseurship, which fits under the broader category of arts-based research. School discipline is a programmatic component of any secondary school’s educational framework and directly effects student engagement and academic achievement. An analysis of the dean role in relation to school discipline is central to this study. The main research question is what are the lived experiences of a dean who incorporates restorative justice practices in a poverty impacted public high school?

The author spent two years as …

Pulmonary Valve Replacement, Mina Shafiei

Electronic Theses and Dissertations

Currently, transcatheter pulmonary valve replacement (TPVR) is a well-established alternative for surgical pulmonary valve replacement (SPVR) to treat pulmonary valve disorders in patients with prior congenital heart surgery. Edwards Sapien 3 valve is a bioprosthesis originally designed for the aortic position but has been used off-label in native right ventricular outflow tract (RVOT). It is currently under clinical trial to get food and drug administration (FDA) approval.

This study is a comparison of the performance of Sapien 3 with surgical bioprosthetics. The in vitro tests result showed Sapien 3 experiences less degree of opening and effective orifice area in pulmonic …

Dynamics And Turnover Of Lipid And Protein Domains In Cells And Supported Bilayers, Alan Weisgerber

Electronic Theses and Dissertations

Protein and lipid clustering is an important mechanism for cell processes such as exo- and endo-cytosis and creating functional signaling complexes. It has been seen that both lipids and proteins are involved with the formation of cluster domains on cell membranes, yet little is known about the interplay between the two. In this work I began with visualizing lipid sorting to artificially induced curvature in supported lipid bilayers, with lipid tails affecting the sorting differently to curvature. These results demonstrate that lipids sort to curvature on curved, supported lipid bilayers. The sorting depends on the number of lipids in the …

Morphological Variation And Community Science In Orthoptera, Amy Byerly

Electronic Theses and Dissertations

Patterns of morphological divergence across species’ ranges provide insight into local adaptation and speciation. Here, we compare phenotypic divergence among 4,221 crickets from 337 populations of two related species of field cricket, Gryllus firmus and G. pennsylvanicus and their hybrids. We find that these species differ across their geographic range in key morphological traits, such as body size and ovipositor length, and we directly compare phenotype with genotype for a subset of crickets demonstrating nuclear genetic introgression, phenotypic intermediacy of hybrids, and essentially unidirectional mitochondrial introgression. We discuss how these morphological traits relate to life history differences between the species. …

Interrupting Holistic Processing May Improve The Detection Of Deceptive Emotional Facial Expressions, Christopher A. Gunderson

Electronic Theses and Dissertations

Although a growing body of evidence suggests that genuine and deceptive facial expressions differ, previous work is mixed as to whether observers can discern between them. One explanation is that cues to deception on the face are subtle and not readily perceived by observers. I argue that the way people process faces may obscure these cues, making them ‘unseen’ by observers. In the current work, I pit two hypotheses against each other to test whether interrupting holistic processing improves or impairs the ability to identify deceptive emotional expressions. Since people process faces holistically, one region of the face may interfere …

Organellar Zn2+ Homeostasis And The Role Of Trpml Channels In Neuronal Lysosome Physiology And Axonal Transport, Taylor Franklin Minckley

Electronic Theses and Dissertations

Zinc (Zn²⁺) is crucial for proper cellular function, and as such it is important to measure and track Zn²⁺ dynamics in living cells. Fluorescent sensors have been used to estimate Zn²⁺ content of subcellular compartments, but little is known about endolysosomal Zn2+ homeostasis. Similarly, although numerous sensors have been reported, it is unclear whether and how Zn²⁺ can be released from intracellular compartments into the cytosol due to a lack of probes that can detect physiological dynamics of cytosolic Zn²⁺. My dissertation started with comparing and characterizing different Zn²⁺ sensors including the …

Experiences Of Chinese American Psychology Trainees In Multicultural Education, Helen Weng-Ian Chao

Electronic Theses and Dissertations

Although research has established that students of color have unique experiences in their multicultural training, few studies have examined the experiences and needs of specific subgroups of students of color. This study examined Chinese American psychology trainees’ experiences in multicultural education. Qualitative data was collected from individual semi-structured interviews with Chinese American doctoral students (N = 6). Interpretative phenomenological analysis was used to understand participants’ perceptions of their experiences in multicultural courses. Data analysis resulted in four themes: the (1) burden of being minoritized, (2) Chinese American identity inflection points, being (3) sidelined by whiteness, and (4) …

Executive Function And Parenting Among Latinx Caregivers Of Young Children, Amy Dominguez Fabatz

Electronic Theses and Dissertations

Supportive and responsive parenting is vital to the healthy development of young children. Parenting behaviors are determined by many factors, including caregivers’ cognitive resources and abilities such as executive functioning (EF). The present study investigated how two core dimensions of EF, working memory and set-shifting abilities, are related to parenting behaviors in a sample of Latinx caregivers of young children experiencing low income. Positive parenting was measured using a multi-method approach including video-coded observations, parent self-report, and evaluation of the home environment. Findings from hierarchical regressions indicated that caregiver working memory, but not set-shifting, predicted positive parenting as measured by …

Exploring Opportunities For Supporting Juvenile Justice-Involved Youth: A Path Forward Through Expanding Graduate Training In School Psychology, Erica L. Gleason

Electronic Theses and Dissertations

School psychologists are equipped with a dynamic skill set and an ethical and moral responsibility to support the diverse needs of all youth. While juvenile justice-involved youth may not be a primary subpopulation served by all school psychologists, they are a high-needs group that requires special consideration and attention. As a professional entity, school psychologists’ knowledge and expertise are not optimally applied to serving these youth. Consequently, school psychologists may be forgoing an opportunity to improve rates of successful school and community reintegration and overall positive life outcomes for justice-involved youth. The first manuscript of this dissertation presents precipitating and …

Dismantling The Education-Survival Complex: A Qualitative Case Study Of How High School Youth Resist Whitestream School Policies And Foster School Change Through A Youth-Development Organization, Tracie Trinidad

Electronic Theses and Dissertations

The aim of this study is to critically examine how youth resist whitestream school policies and foster educational change through community sociopolitical youth-development organizations. The methodology for this study is a qualitative case study (Fraenkel & Wallen, 1990; Merriam, 1988), as I am focused on participant perceptions and experiences, and how they make sense of their resistance experience through participation in sociopolitical youth development organizations like Youth for Social and Political Activism (YSPA). In total, eight participants spoke about their racial identity through their lived experiences in public school and YSPA programming.

The data and analysis are presented in the …

Faculty Facilitation Of Help-Seeking On Campus: A Phenomenological Study, Lillian V. Clark

Electronic Theses and Dissertations

An ever-increasing number of students on college campuses are experiencing distress, and not all students in need of care are being reached (Kitzrow, 2009, LeViness, et al., 2019). Faculty are one of the most valuable resources for identifying and connecting students to care (Kitzrow, 2009). Despite this, we know very little about the experiences of faculty working with students in distress. This study sought to understand those experiences, as well as identify the barriers to connecting students to care. A qualitative study using an Interpretive Phenomenology framework was conducted (Smith & Osborn, 2007, Moustakas, 1994). Four themes were interpreted from …

“I, Too, Am An Occupied Territory”: Border Crossings And Personal Sovereignty In Three Novels By Dominican American Women, Leia M. Lynn

Electronic Theses and Dissertations

Border crossing(s) and personal sovereignty are intimately and complexly connected in novels by and about Dominican American women. Through readings of In the Name of Salomé by Julia Alvarez, Dominicana by Angie Cruz, and The Poet X by Elizabeth Acevedo, I argue that patriarchal forms of authority remove female autonomy by trespassing on personal boundaries, and that the renegotiation of that power is achieved through formations of community, especially with other women, through nonheteronormative relationships that are present inside and extend outside the text. The interplay of patriarchal authority, violence, and alienation on the four protagonists is examined at length, …

Improving Vocabulary Outcomes Through Language Resources: A Single Case Design Of First Grade Emergent Bilinguals Engaged In Literacy Intervention, Brooke S, Coté

Electronic Theses and Dissertations

While there is a strong literature base demonstrating the importance of early literacy interventions for monolingual learners at-risk for reading difficulties, little research exists on how to effectively support the literacy needs and language assets of emergent bilinguals. The purpose of this study was to investigate the effect of an evidence-based reading intervention with a translanguaging component, on vocabulary outcomes for first grade emergent bilinguals. By utilizing an alternating treatment single case design with two conditions, this project aimed to address the following research questions: Is there a functional relationship between an evidence-based reading intervention with a translanguaging component compared …

Opportunities And Challenges For Rural Educators: A Mixed Methods Study Of Emergent Bilingual Studies In Rural Colorado, Andrea Johnson

Electronic Theses and Dissertations

Over nine million students in the United States attend school in rural school districts, with a growing percentage of these students identified as emergent bilingual. The purpose of this study is to examine the national emergent bilingual literacy trends and to determine how the opportunities and challenges that rural educators encounter, impact emergent bilingual education in rural schools. Utilizing a theoretical framework of culturally sustaining practices and funds of knowledge, this study uses a convergent mixed methods design to answer the following research questions: What are the national trends in emergent bilingual reading test scores? What opportunities and challenges do …

Topics In Moufang Loops, Riley Britten

Electronic Theses and Dissertations

We will begin by discussing power graphs of Moufang loops. We are able to show that as in groups the directed power graph of a Moufang loop is uniquely determined by the undirected power graph. In the process of proving this result we define the generalized octonion loops, a variety of Moufang loops which behave analogously to the generalized quaternion groups. We proceed to investigate para-F quasigroups, a variety of quasigroups which we show are antilinear over Moufang loops. We briefly depart from the context of Moufang loops to discuss solvability in general loops. We then prove some results on …

Development And Testing Of Remote Facilitation Of Prevent-Teach-Reinforce For Families To Address Challenging Behavior In Young Children (Ptr-F:R), Abby Hodges

Electronic Theses and Dissertations

As children advance through developmental stages, they often present behavioral difficulties such as tantrums, lack of cooperation, and aggression. For some children, behaviors are serious enough that they interfere with the child’s ability to engage in positive relationships, participate in necessary routines, and learn new skills, warranting behavioral intervention (Dunlap et al., 2017). Being responsive to the needs of the family and appreciation for the central role that they play is crucial to the success of behavioral interventions and the maintenance of positive outcomes (Bailey, 2013; Campbell, 1995), thus, their input should be at the center of all recommendations and …

Addressing Racial Disparities Through K-12 School-Based Culturally Relevant Interventions, Dina Malala

Electronic Theses and Dissertations

This meta-analysis systematically identified culturally relevant interventions for Black students in K-12 school settings to determine (a) the effect of culturally relevant reading interventions on reading comprehension and reading fluency (b) the effect of culturally relevant behavioral interventions on student behaviors (c) the extent to which culturally relevant interventions impact cultural identity and awareness (d) how cultural identity moderates academic and behavioral outcomes. Twelve studies were identified. Overall, there was a statistically significant combined effect across the twelve studies (g = 0.96, p < 0.05). There was a statistically significant effect of culturally relevant reading interventions on reading outcomes (g =1.174, p < 0.05), a statistically significant effect of culturally relevant behavior interventions on behavior outcomes (g = 0.889, p < 0.05), and a statistically significant effect of cultural identity interventions on cultural awareness and identity (g =0. 914, p < 0.05). The primary limitation of this meta-analysis are the mainstream and standardized dependent variables. Future intervention research is needed that utilizes both culturally relevant independent and dependent variables to better support this population.

Application Of An Organizational Evaluation Capacity Assessment In A Multinational Ngo: A Case Study To Support Applied Practice, Ryan James Smyth

Electronic Theses and Dissertations

As evaluation capacity building (ECB) has rapidly emerged as a practice in human service organizations and as a field of academic inquiry, attention has focused on methods of evaluation capacity building while assessment of organizational evaluation capacity (EC) has lagged behind. To examine the practice of organizational evaluation capacity assessment, this dissertation presents two separate but related studies. In sub-study 1, I present a qualitative evidence synthesis of the research theorizing organizational evaluation capacity models. In sub-study 2, I support the implementation of one of the tools from the evidence-synthesis at a multinational human service organization. I use a concurrent …

Understanding Critical Reflection As A Leadership Development Methodology, Matthew M. Orlowsky

Electronic Theses and Dissertations

How do leaders translate experiences into insights? Critical reflection is offered as a leadership development process that illuminates effective practices following an empirical analysis of 352 United States Air Force Academy cadet essays that describe their most profound leadership experiences. These essays are iteratively analyzed and interpreted using the critical reflection methodology. The essays were examined to find how young leaders turn experiences into leadership insights. The study takes advantage of the distinctive Academy leadership development context and the data available from cadets’ essays describing their profound leadership experiences. There are three contributions bounded in this dissertation and multiple avenues …

Phosphatidylserine Externalization On Non-Apoptotic Cells And Lipid Scramblases In C. Elegans, Julia Frondoni

Electronic Theses and Dissertations

Cell corpse clearance is key for animals to avoid inflammation and autoimmune disease. To better understand the “eat me” signal of phosphatidylserine (PS) exposure for non-apoptotic corpse clearance, we attempted to disrupt the externalization of PS on C. elegans polar bodies. The second polar body undergoes a non-apoptotic form of cell death, loses membrane integrity, externalizes PS and is cleared by embryonic cells during early development. During apoptotic and necrotic cell death, PS asymmetry is disrupted by lipid scramblases, which translocate phospholipids between the leaflets of the lipid bilayer. We found neither apoptotic nor necrotic scramblases are required for PS …

Development And Initial Validation Of An Acculturation Measure For Arab Expatriates In Qatar Using Mixed Methods, Sara Ali Ahmed Zikri

Electronic Theses and Dissertations

Prior research on acculturation has predominantly focused on specific immigrant and ethnic groups in the United States, Europe, and Asia, and there is a lack of publicly available scales that measure acculturation among expatriates in countries of the Gulf Cooperation Council. The purpose of this study was to use a mixed methods research design to develop a theoretical framework of acculturation for white-collar Arab expatriates in Qatar as well as a culturally appropriate self-report acculturation measure. The acculturation stories and experiences of white-collar Arab expatriates in Qatar were qualitatively explored and analyzed, and their findings were used to construct an …

Does The Contraction History Of The Muscle Dictate Changes In Strength Following Resistance Training?, Zachary William Bell

Electronic Theses and Dissertations

Within-subject training models, whereby researchers apply an exercise condition to one limb, and a separate exercise condition to the opposing limb, have become routine amongst the exercise literature. However, no study has directly tested whether exercising one limb with a high-load condition will influence strength adaptations within the opposing limb, even when the opposite limb is training. Furthermore, muscle post-activation performance enhancement (PAPE) is representing local level changes, however, more research is warranted to understand if this can be differentially impacted with different types (e.g. low load vs. high load) of resistance training. The purpose of this study was to …

Serially Concatenated Continuous Phase Modulation With Sova Turbo Decoding, Zhijie Guo

Electronic Theses and Dissertations

For a Serially Concatenated Continuous Phase Modulation (SCCPM) system that concatenates a rate of 1/2 Convolutional Code (CC) and an M-ary full response continuous phase modulation (CPM) signal, we design a turbo decoding scheme using the Soft Output Viterbi algorithm (SOVA) and study the system performance. A decomposition model is used in CPM to reduce the number of states and separate the continuous phase encoder (CPE) with the modulator. As a soft-input soft-output (SISO) decoding algorithm, SOVA is used to generate and update the soft information of decoded signal symbols during the iterative process for both the CPM signal and …

Investigations Of Molecular Complexes For Catalytic Water Oxidation And Carbon Dioxide Reduction, Sha Tamanna Sahil

Electronic Theses and Dissertations

Modern society and technological advancements rely on a reliable and continuous supply of energy. The sun has always been the ultimate source of energy and mediated by mother nature; however, the continued reliance and use of fossil fuel resources (i.e. coal, oil, and natural gas) is causing increasingly negative environmental effects. For instance, the emission of tons of greenhouse gases from fossil fuel combustion is a leading cause of global warming, rising sea levels, and human health issues. Indeed, the concentration of CO2, a product of combustion, recently exceeded 415 ppm, rising from a pre-industrial level of less than 300 …

Emotional Carry-Over In Ethical Decision Making: The Impact Of Self-Control And Moral Potentcy, Franklin Faison Tillman

Electronic Theses and Dissertations

Recent theories have posited that emotions play a central role in ethical decision making. However, most research has focused on and suggested that consumers follow cognitive, rational processes in decision making. While this is a well-established approach, research regarding the role of emotions in ethical decision making has gained considerable theoretical attention in recent years. Although various factors have been investigated for the influence on ethical judgments, the role of task related, and incidental emotions have received less attention. Theoretical models that examine ethical decision-making conflict at times and are historically divided into either a rational-based approach or a non-rationalist-based …

Exploring The Standard Model And Beyond Using B And D Meson Decays, John Waite

Electronic Theses and Dissertations

In this research, I have tested the standard model(SM) and various new physics (NP) models using B and D meson decays. In D meson decays, the SU(3) flavor symmetry of the SM for Cabibbo favored decays is tested against experimental measurements. The SU(3) analysis with η and η′ are considered in a general and consistent way for the first time. In B decays, a fit to the data for four B → πK decays is performed, within the SM and with NP. The fit confirms that the SM gives a poor fit to the B → πK data which is …