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Pseudomonas Aeruginosa 1244 Pilin Glycosylation: Substrate Specificity, Glycan Functionality, And Application For Vaccine Development, Joseph Horzempa Jan 2006

Pseudomonas Aeruginosa 1244 Pilin Glycosylation: Substrate Specificity, Glycan Functionality, And Application For Vaccine Development, Joseph Horzempa

Electronic Theses and Dissertations

Pseudomonas aeruginosa expresses type IV pili, which are polymeric fibrous surface appendages extending from the poles of the cell that function in adhesion and surface motility. The monomeric pilus subunit, pilin, of P. aeruginosa 1244 is glycosylated with an oligosaccharide that is structurally identical to the O-antigen repeating unit of this organism. Work presented here identifies the pilin structures necessary for glycosylation. Results suggested that the C-terminal Ser of pilin is the major glycosylation recognition feature, and this residue cannot be substituted at its carboxyl group. While no other specific recognition features are present, the pilin surface must be compatible …

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Notopleural Mutations Enhance Defects In Imaginal Disc Epithelial Morphogenesis And Macrochete Elongation Associated With Mutations In The Stubble-Stubbloid Locus, Robert Ruggiero Jan 2006

Notopleural Mutations Enhance Defects In Imaginal Disc Epithelial Morphogenesis And Macrochete Elongation Associated With Mutations In The Stubble-Stubbloid Locus, Robert Ruggiero

Electronic Theses and Dissertations

The Stubble-stubbloid locus encodes a transmembrane serine protease (Stubble) necessary for the proper formation of sensory bristles, and the morphogenesis of leg and wing epithelia. Genetic and cell biological analysis indicate a role for Stubble in actin cytoskeletal dynamics and cell shape changes in developing epithelia and bristles. Previously reported genetic interactions between Stubble and the Rho1 signaling pathway suggest Stubble influences actin cytoskeleton dynamics in developing imaginal discs through interactions with the Rho1 pathway. This work will discuss a genetic screen conducted to further investigate the role of Stubble in bristle and imaginal disc morphogenesis. From 50,000 EMS-mutagenized chromosomes …

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A Compartive Analysis Of The Evolution Of Forest Management In The United States In General, With A Focus On Oregon, North Carolina, Patrick Kelly Jan 2006

A Compartive Analysis Of The Evolution Of Forest Management In The United States In General, With A Focus On Oregon, North Carolina, Patrick Kelly

Electronic Theses and Dissertations

The purpose of this paper is to evaluate and discuss the evolution of forest management practices in the United States. The paper discusses the trends in forest management that have occurred within the United States in general, and specifically within the western (Oregon) and southern (North Carolina and Florida) United States. The trends discussed include the three (3) to four (4) epochs of management and use that are generally accepted within the forest management literature, with the exception of North Carolina that is in the process of a fifth (5). The comparative analysis within the paper discusses the western model …

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Mapping And Characterization Of 18-5 And 12-5, Genes Which Potentially Link The Rhoa Signaling Pathway To The Ecdysone Response, Samuel Fox Jan 2006

Mapping And Characterization Of 18-5 And 12-5, Genes Which Potentially Link The Rhoa Signaling Pathway To The Ecdysone Response, Samuel Fox

Electronic Theses and Dissertations

Systemic steroid hormone and intracellular signaling pathways are known to act cooperatively during the development of vertebrate and invertebrate epithelia. However, the mechanism of this interaction is poorly understood. Morphogenesis of Drosophila leg imaginal disc epithelia is regulated both by the steroid hormone 20-hydroxyecdysone (ecdysone) and the RhoA GTPase signaling pathway. Recent evidence suggests that these pathways act cooperatively to control imaginal disc morphogenesis. Thus, leg imaginal disc morphogenesis is an excellent system in which to study the interaction of steroid hormone and intracellular signaling pathways. We have identified mutations in three genes, 12-5, 18-5, and 31-6, with roles in …

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Dispersal Behavior Of Mosquitofish (Gambusia Holbrooki), Shireen Alemadi Jan 2006

Dispersal Behavior Of Mosquitofish (Gambusia Holbrooki), Shireen Alemadi

Electronic Theses and Dissertations

Mosquitofish (Gambusia holbrooki) are native to the southeastern United States but invasive elsewhere, and are dominant predators in many ecosystems that they inhabit. Information on dispersal behavior will help better understand and predict mosquitofish metapopulation dynamics and invasions. I experimentally tested dispersal behavior of individual mosquitofish under a range of laboratory conditions relevant to field situations. Preliminary experiments showed that gender, lighting conditions, hunger and acclimation time did not significantly affect net dispersal rate. Power analysis based on this preliminary experiment determined that 6 replicate fish were sufficient for each subsequent experiment; I used 24 fish, and each fish was …

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A Common Component-Based Software Architecture For Military And Commercial Pc-Based Virtual Simulation, Joshua Lewis Jan 2006

A Common Component-Based Software Architecture For Military And Commercial Pc-Based Virtual Simulation, Joshua Lewis

Electronic Theses and Dissertations

Commercially available military-themed virtual simulations have been developed and sold for entertainment since the beginning of the personal computing era. There exists an intense interest by various branches of the military to leverage the technological advances of the personal computing and video game industries to provide low cost military training. By nature of the content of the commercial military-themed virtual simulations, a large overlap has grown between the interests, resources, standards, and technology of the computer entertainment industry and military training branches. This research attempts to identify these commonalities with the purpose of systematically designing and evaluating a common component-based …

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User-Centered Virtual Environment Assessment And Design For Cognitive Rehabilitation Applications, Cali Fidopiastis Jan 2006

User-Centered Virtual Environment Assessment And Design For Cognitive Rehabilitation Applications, Cali Fidopiastis

Electronic Theses and Dissertations

Virtual environment (VE) design for cognitive rehabilitation necessitates a new methodology to ensure the validity of the resulting rehabilitation assessment. We propose that benchmarking the VE system technology utilizing a user-centered approach should precede the VE construction. Further, user performance baselines should be measured throughout testing as a control for adaptive effects that may confound the metrics chosen to evaluate the rehabilitation treatment. To support these claims we present data obtained from two modules of a user-centered head-mounted display (HMD) assessment battery, specifically resolution visual acuity and stereoacuity. Resolution visual acuity and stereoacuity assessments provide information about the image quality …

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A Holistic Usability Framework For Distributed Simulation Systems, Jeffrey Dawson Jan 2006

A Holistic Usability Framework For Distributed Simulation Systems, Jeffrey Dawson

Electronic Theses and Dissertations

This dissertation develops a holistic usability framework for distributed simulation systems (DSSs). The framework is developed considering relevant research in human-computer interaction, computer science, technical writing, engineering, management, and psychology. The methodology used consists of three steps: (1) framework development, (2) surveys of users to validate and refine the framework, and to determine attribute weights, and (3) application of the framework to two real-world systems. The concept of a holistic usability framework for DSSs arose during a project to improve the usability of the Virtual Test Bed, a prototypical DSS, and the framework is partly a result of that project. …

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Automated Scenario Generation System In A Simulation, Hajime Tomizawa Jan 2006

Automated Scenario Generation System In A Simulation, Hajime Tomizawa

Electronic Theses and Dissertations

Developing training scenarios that induce a trainee to utilize specific skills is one of the facets of simulation-based training that requires significant effort. Simulation-based training systems have become more complex in recent years. Because of this added complexity, the amount of effort required to generate and maintain training scenarios has increased. This thesis describes an investigation into automating the scenario generation process. The Automated Scenario Generation System (ASGS) generates expected action flow as contexts in chronological order from several events and tasks with estimated time for the entire training mission. When the training objectives and conditions are defined, the ASGS …

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Performance Efficacy Using A Comparison Of Commerical And In-House Y-Str Multiplex Systems For Operational Use, Kathleen Mayntz-Press Jan 2006

Performance Efficacy Using A Comparison Of Commerical And In-House Y-Str Multiplex Systems For Operational Use, Kathleen Mayntz-Press

Electronic Theses and Dissertations

It is routine for the forensic scientist to obtain a genetic profile of an individual from DNA recovered from a biological stain deposited at a crime scene. In contrast, only a limited number of laboratories in the United States have the capability of performing Y-STR analysis in casework. In order to aid in facilitating the transfer of Y-STR technology to the crime laboratory community for operational use, a comparison between commercial products from three main vendors (Applied Biosystems AmpFLSTR Yfiler PCR Amplification Kit, Promega PowerPlex - Y System, Reliagene Y-PLEX 12) and two in-house Y-STR multiplexes (MPI and MPB) commenced. …

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Kantian Meadows: A Just Nursing Home Grounded In The Categorical Imperative, Faith Bjalobok Jan 2006

Kantian Meadows: A Just Nursing Home Grounded In The Categorical Imperative, Faith Bjalobok

Electronic Theses and Dissertations

This dissertation examines the structures of contemporary nursing homes and argues that the structure is conducive to the objectification (treatment of a human being as a non-person) of nursing home residents. In order to eliminate the potential for objectification, this project employs the Kantian categorical imperative as its theoretical framework. Based on that framework Kantian Meadows is created as an example of a just nursing home.

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Examining Route Diversion And Multiple Ramp Metering Strategies For Reducing Real-Time Crash Risk On Urban Freeways, Vikash Gayah Jan 2006

Examining Route Diversion And Multiple Ramp Metering Strategies For Reducing Real-Time Crash Risk On Urban Freeways, Vikash Gayah

Electronic Theses and Dissertations

Recent research at the University of Central Florida addressing crashes on Interstate-4 in Orlando, Florida has led to the creation of new statistical models capable of calculating the crash risk on the freeway (Abdel-Aty et al., 2004; 2005, Pande and Abdel-Aty, 2006). These models yield the rear-end and lane-change crash risk along the freeway in real-time by using static information at various locations along the freeway as well as real-time traffic data that is obtained from the roadway. Because these models use the real-time traffic data, they are capable of calculating the respective crash risk values as the traffic flow …

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Cognitive Training Transfer Using A Personal Computer-Based Game:A Close Quarters Battle Case Study, Michael Woodman Jan 2006

Cognitive Training Transfer Using A Personal Computer-Based Game:A Close Quarters Battle Case Study, Michael Woodman

Electronic Theses and Dissertations

Developers of Commercial off the Shelf (COTS) gaming software are making remarkable strides in increasing the realism of their software. This realism has caught the attention of the training community, which has traditionally sought system and operational replication in training systems such as flight simulators. Since games are designed and marketed for entertainment and not designed for training of tasks, questions exist about the effectiveness of games as a training system in achieving the desired transfer of skills to the actual environment. Numerous studies over the past ten years have documented that PC-based simulation training environments can offer effective training …

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Fundamental Aspects Of Regenerative Cerium Oxide Nanoparticles And Their Applications In Nanobiotechnology, Swanand Patil Jan 2006

Fundamental Aspects Of Regenerative Cerium Oxide Nanoparticles And Their Applications In Nanobiotechnology, Swanand Patil

Electronic Theses and Dissertations

Cerium oxide has been used extensively for various applications over the past two decades. The use of cerium oxide nanoparticles is beneficial in present applications and can open avenues for future applications. The present study utilizes the microemulsion technique to synthesize uniformly distributed cerium oxide nanoparticles. The same technique was also used to synthesize cerium oxide nanoparticles doped with trivalent elements (La and Nd). The fundamental study of cerium oxide nanoparticles identified variations in properties as a function of particle size and also due to doping with trivalent elements (La and Nd). It was found that the lattice parameter of …

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Modeling Autonomous Agents In Military Simulations, Varol Kaptan Jan 2006

Modeling Autonomous Agents In Military Simulations, Varol Kaptan

Electronic Theses and Dissertations

Simulation is an important tool for prediction and assessment of the behavior of complex systems and situations. The importance of simulation has increased tremendously during the last few decades, mainly because the rapid pace of development in the field of electronics has turned the computer from a costly and obscure piece of equipment to a cheap ubiquitous tool which is now an integral part of our daily lives. While such technological improvements make it easier to analyze well-understood deterministic systems, increase in speed and storage capacity alone are not enough when simulating situations where human beings and their behavior are …

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Characterization Of Critical Network Components Of Coupled Oscillators, Gregory Holifield Jan 2006

Characterization Of Critical Network Components Of Coupled Oscillators, Gregory Holifield

Electronic Theses and Dissertations

This dissertation analyzes the fundamental limits for the determination of the network structure of loosely coupled oscillators based on observing the behavior of the network, specifically, node synchronization. The determination of the requisite characteristics and underlying behaviors necessary for the application of a theoretical mechanism for determining the underlying network topology in a network of loosely coupled natural oscillators are the desired outcome. To that end, this effort defines an analytical framework where key components of networks of coupled oscillators are isolated in order to determine the relationships between the various components. The relationship between the number of nodes in …

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Parameter Estimation In Linear Regression, Kati Ollikainen Jan 2006

Parameter Estimation In Linear Regression, Kati Ollikainen

Electronic Theses and Dissertations

Today increasing amounts of data are available for analysis purposes and often times for resource allocation. One method for analysis is linear regression which utilizes the least squares estimation technique to estimate a model's parameters. This research investigated, from a user's perspective, the ability of linear regression to estimate the parameters' confidence intervals at the usual 95% level for medium sized data sets. A controlled environment using simulation with known data characteristics (clean data, bias and or multicollinearity present) was used to show underlying problems exist with confidence intervals not including the true parameter (even though the variable was selected). …

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Computer-Based Instructional Systems Design Tools: Current State And Implications For The Future, Anna A. Andrews Jan 2006

Computer-Based Instructional Systems Design Tools: Current State And Implications For The Future, Anna A. Andrews

Electronic Theses and Dissertations

This study examines the current state of computer-based instructional systems design (ISD) tools and outlines its implications for the future. The study utilizes the grounded theory methodology to capture and document modern instructional designers' perspectives regarding the current state of ISD tools, the issues associated with them, and their interrelationships. The study also presents a framework for classifying modern ISD tools and a conceptual prototype of a designer-oriented system of computer-based ISD tools.

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Searching For A Place : Community As Resistance In Black Literatures / By Jon Matthew Saye, Jon Matthew Saye Jan 2006

Searching For A Place : Community As Resistance In Black Literatures / By Jon Matthew Saye, Jon Matthew Saye

Electronic Theses and Dissertations

No abstract provided.

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Central Effects Of Aminopeptidase-Resistant Analogs Of Ang Ii In The Rat, Ranjita J. Kokje Jan 2006

Central Effects Of Aminopeptidase-Resistant Analogs Of Ang Ii In The Rat, Ranjita J. Kokje

Electronic Theses and Dissertations

No abstract provided.

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Nitrogen Use Efficiency In Cyperus Haspan, A Cγéâ Wetland Sedge, In A Six-Month Greenhouse Experiment At The University Of Mississippi Field Station, Alison Avery Faulkner Jan 2006

Nitrogen Use Efficiency In Cyperus Haspan, A Cγéâ Wetland Sedge, In A Six-Month Greenhouse Experiment At The University Of Mississippi Field Station, Alison Avery Faulkner

Electronic Theses and Dissertations

No abstract provided.

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Walking The Tightrope : Complicated Motherhood In Ernest Gaines's A Long Day In November And The Sky Is Gray, Mary Amanda Murfee Jan 2006

Walking The Tightrope : Complicated Motherhood In Ernest Gaines's A Long Day In November And The Sky Is Gray, Mary Amanda Murfee

Electronic Theses and Dissertations

No abstract provided.

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Cultivating The Wild Land : The Industrialization Of Agriculture And Willa Cather's Great Plains Farm Novels, Amanda Kuhnel Jan 2006

Cultivating The Wild Land : The Industrialization Of Agriculture And Willa Cather's Great Plains Farm Novels, Amanda Kuhnel

Electronic Theses and Dissertations

No abstract provided.

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The Nocturnal Museum, James Everett Jan 2006

The Nocturnal Museum, James Everett

Electronic Theses and Dissertations

No abstract provided.

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Mass Media Convergence : A Guide For Student And Professional Media Centers, Rima Chaddha Jan 2006

Mass Media Convergence : A Guide For Student And Professional Media Centers, Rima Chaddha

Electronic Theses and Dissertations

No abstract provided.

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Experimental Characterization Of Environmentally Friendly Treated Wood Core Pultruded Composites, Brittany Hancock Jan 2006

Experimental Characterization Of Environmentally Friendly Treated Wood Core Pultruded Composites, Brittany Hancock

Electronic Theses and Dissertations

No abstract provided.

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Effect Of Clay And Organic Content On The Acoustic Behavior Of Sediment Saturated By Water Or Atrazine, Sireesha Gudipudi Jan 2006

Effect Of Clay And Organic Content On The Acoustic Behavior Of Sediment Saturated By Water Or Atrazine, Sireesha Gudipudi

Electronic Theses and Dissertations

No abstract provided.

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Ethanol Toxicity In Japanese Medaka Embryogenesis : A Mechanistic Study / By Xueqing Wang, Xueqing Wang Jan 2006

Ethanol Toxicity In Japanese Medaka Embryogenesis : A Mechanistic Study / By Xueqing Wang, Xueqing Wang

Electronic Theses and Dissertations

No abstract provided.

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The Ploofop Refugees / By Neal Walsh, Neal Walsh Jan 2006

The Ploofop Refugees / By Neal Walsh, Neal Walsh

Electronic Theses and Dissertations

No abstract provided.

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Microbial Modification Of Corn Stover To Increase Ethanol Yield, Naresh K. Budhavaram Jan 2006

Microbial Modification Of Corn Stover To Increase Ethanol Yield, Naresh K. Budhavaram

Electronic Theses and Dissertations

No abstract provided.

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