Digital Commons Network^™

Novel Hepatitis C Virus (Hcv) Community Viral Load Measures, Hcv Incidence And Prevalence, And Hcv Prevention By Methadone Maintenance, Ashly E. Jordan

Dissertations and Theses

Abstract

Introduction

The incidence of Hepatitis C virus (HCV) infection has increased in the current opioid epidemic in the United States; current estimates are that 2-3 million Americans have HCV infection. The ongoing and increasing HCV epidemic among people who use drugs (PWUD) is occurring in the context of known HCV prevention and highly efficacious and well-tolerated curative HCV treatment. The development of direct acting antivirals (DAAs) with cure rates approaching 100% dramatically changed the treatment landscape. This provides both the potential for improved individual- and population-level treatment effectiveness, and also the potential for population-level HCV ‘cure as prevention' (CasP) …

Ecosystem Health In Guánica Bay And La Parguera, Puerto Rico: Remote Sensing Of Ocean Color And Metal Analysis Of Coral Tissue And Surficial Sediments, Jahnelle Howe

Dissertations and Theses

Guánica Bay is an estuary located in southwest Puerto Rico, with a coral reef ecosystem at its periphery. This ecosystem is affected by sediments, nutrients, and contaminants from the watershed through the Bay and into the offshore water. This project evaluates Guánica Bay and La Parguera coastal areas through remote sensing and chemical analysis to assess coastal ecosystem health. The concentration of metals in two coral species and their associated surface sediments was were analyzed by X-ray fluorescence (XRF) and Direct Mercury Analyzer (DMA- 80). Ocean color remote sensing was used to estimate nutrient inputs and phytoplankton biomass through chlorophyll- …

Innovative Applications Of Laser Remote Sensing Of Gases, Aerosols And Wind, Adrian Diaz Fortich

Dissertations and Theses

Over the years, a major component of the research carried out at the Optical Remote Sensing Laboratory of the City College of New York has been on active sensing technologies and their different applications in atmospheric studies. This thesis builds upon and looks to further advance this field by demonstrating innovative applications of laser remote sensing technologies for studies involving trace gases, aerosol particles and wind; which are key components of the Earth’s atmosphere. First, we present the demonstration of gas concentration measurements using a quantum cascade laser open path system with characteristics that make it promising for mobile and/or …

Mems Biosensor For Water-Immersed Application, Kun-Lin Lee

Dissertations and Theses

Although many air-based sensing mechanisms exist, not all of them can be applied in the water-based environment. In order to obtain a cell-based biosensor, the sensing method needs to be reliable and repeatable in a liquid environment. Therefore, this study is focused on transforming existing air-based sensors to water-immersed applications. This study includes two types of sensors.

First, commercial quartz resonators are used to investigate live-cell activity in water-based toxic solutions. I perform toxicity tests using quartz crystal microbalance (QCM). The QCM used in the study has a resonant frequency of 10 MHz and consists of an AT-cut quartz crystal …

Influence Of Transdermal Current Flow In Tdcs-Induced Cutaneous Adverse Events, Niranjan Khadka

Dissertations and Theses

Significant contributors to the broad application of transcranial direct current stimulation (tDCS) are portability, ease-of-use, and tolerability; with adverse events limited to transient and mild cutaneous sensations (e.g. perception of burning, itching, and tingling) and erythema. However, the fundamental questions remain about the mechanism of transdermal current flow during transcranial electrical stimulation, including tDCS. Example of previously unexplained questions in tDCS include: 1) the relationship between tDCS-induced skin reddening (erythema) profile and local current density profile predicted by the model; 2) the source of burning sensation during tDCS and whether it is related to an actual skin heating; 3) the …

Macro - And Microstructure Evaluation And Field Applications Of Concrete With Recycled Glass Pozzolan, Marija Krstic

Dissertations and Theses

Concrete is the most used material in the world, second only to water. Conventional concrete is produced with Portland cement (PC). The production of cement is an energy intensive operation that has raised significant environmental concerns, since one ton of cement generates an equal ton of CO₂. In the USA about 90 million tons of cement are used annually, with 3 million tons used in New York. Most contemporary concrete applications for buildings and infrastructure use high-performance concrete (HPC) mixtures which are produced by replacing a percentage of cement with supplementary cementitious materials (SCMs), consisting mainly of fly-ash …

A Micromechanics Study On Ferroelectrics And Multiferroic Composites, Zhiming Hu

Dissertations and Theses

Two kinds of modern composites are studied in this thesis. One is ferroelectric materials, and the other is the multiferroic composites. Based upon the essential properties of these two types materials, several issues need to be considered in order to study their effective properties. For example, the microstructures of the system including the shape, size and the distribution; the phase connectivity; and the loading conditions will impact the results. First, we focus on the investigation of ferroelectrics and its composites. Based on the experimental observations, the nonlinear electromechanical coupling responses of ferroelectrics are strongly depending on the frequency of the …

Diffuse Damage Repair Mechanism In Bone, Leila Mehraban Alvandi

Dissertations and Theses

Bone microdamage is a result of fatigue, creep or ‘wear and tear’ caused by physiological activities and largely contributes to bone fragility. Bone, unlike engineered materials, has the ability to repair the microscopic cracking or microdamage through targeted, osteoclast-mediated bone remodeling. This capability is crucial for preservation of its structural integrity and quality; failure of the skeleton to effectively repair microdamage leads to accumulation of damage, which is one of the main contributors to bone fragility. Linear microcracks (50-100 µm) and diffuse damage (Dif.Dx) (sub-micron) are the two types of microdamage. Recent studies show that Dif.Dx repairs without bone remodeling, …

Characterization Of Bone Pathology In Sickle Cell Disease And Therapeutic Strategies, Mykel D. Green

Dissertations and Theses

Sickle cell disease (SCD) is a genetic hemoglobinopathy that has grown into a global health concern. While the advances in medical treatment and management of SCD during childhood have drastically improved the overall survival of children, the transition from pediatric to adult services is significantly inadequate in comparison. Life expectancies of patients with SCD in first world countries such as the United States are shortened to averages of 42 and 48 years for men and women, respectively. Despite the increasing number of people living with SCD, remarkably, few detailed studies have described the clinical course and complications of the disease …

Adapting To Extreme Heat: Social, Atmospheric, And Infrastructure Impacts Of Air Conditioning In Megacities - The Case Of New York City, Harold Gamarro

Dissertations and Theses

Extreme heat events are becoming more frequent and intense in most large cities. Built-up surfaces also limit cooling mechanisms, leading to warmer conditions in cities, a phenomenon called the Urban Heat Island (UHI). This presents major challenges to reduce adverse health effects of hot weather, particularly in vulnerable populations like the elderly and low-income communities. Here we explore the overall impacts of increasing air conditioning (AC) system adoption in residences as an adaptive measure to reduce human health risks under heat waves, with New York City (NYC) as a case study. This study uses AC adoption data from the 2017 …

Investigation Of Asphaltene Adsorption At Liquid-Liquid And Liquid-Solid Interfaces, Fang Liu

Dissertations and Theses

Asphaltenes, as indigenous components in crude oils, are believed to play an important role in the petroleum production and processing industry. For example, asphaltene molecules can adsorb onto the water / oil interface like the amphiphiles and hinder water droplet coalescence, resulting in the stabilization of water-in-oil emulsions. Also, in the upstream production, depending on the temperature and pressure, asphaltenes can precipitate and deposit onto the reservoir rocks, the wellbores and the pipelines, leading to the change in reservoir rocks’ surface wettability and the blockage of the production facilities. Hence, it is crucial to understand the mechanism of asphaltenes adsorption …

Capillary Forces And Wetting Dynamics By Diffuse-Interface Modeling, Fanny Thomas

Dissertations and Theses

Wetting phenomena underlie many natural and industrial processes, from the proper functioning of the lungs to the thin coating of surfaces. The three-phase interactions involved at microscopic scales play a critical role. Adding solid particles to an emulsion, for example, can drastically change the flow behavior due to capillary bridging between the particles. The study of these three-phase systems is especially relevant to the petroleum industry, where gas hydrates forming large clusters in subsea pipelines during crude oil transportation is a major concern. The dynamics of such systems is also of great interest from a fundamental perspective. Indeed describing non-equilibrium …

Bird Of The Air And Sweetness Of The Snowe, Steve Mendoza

Dissertations and Theses

No abstract provided.

Humayun Ahmed And Archival Hauntings: The Subaltern Experience Of The 1971 Liberation War Of Bangladesh As Portrayed In Debi, Nilima Islam

Dissertations and Theses

In this paper, I argue how Humayun Ahmed's Debi offers insight into the function that archives play in creating radical nationalism in a country like Bangladesh; how these archives work to consolidate political power for a select few, and how they further subjugate and silence the country’s subalterns.

Microbial Degradability Of Terrigenous, Marsh-Exported, And Estuarine Colored Dissolved Organic Matter In Long Island Sound, John R. Supino

Dissertations and Theses

The Long Island Sound is one of the world's most urbanized estuaries, polluted from excess nutrients which impact the quality of water through increased biological productivity. Dissolved organic matter (DOM) is a sensitive indicator of anthropogenic pollution and nutrient enrichment in coastal waters as well as an important part of the carbon cycle and serves as a primary food source for aquatic food webs. Additionally, the colored portion of DOM (CDOM) impacts coastal optical properties, ocean color, and light attenuation. High levels of CDOM have been shown to inhibit the growth of phytoplankton and limit photosynthesis, damaging the food chain …

Walking Through Fire: Black Men’S Quest For Autonomy In August Wilson’S Two Trains Running And King Hedley Ii, Natasha Young

Dissertations and Theses

This paper explores Black male characters in August Wilson's Two Trains Running and King Hedley II. Characters in these plays seek personal autonomy through economic stability. They seek these things during the turbulent times of the 1960's and 1980's in Pittsburgh, Pennsylvania's Hill District. The roads they take are filled with self discovery, humility and peril.

The Dark Underbellies Of The Littles: A History Of The Indo-Guyanese Diaspora, Race And Identity, Kiran J. Baldeo

Dissertations and Theses

This historical analysis explores Guyanese immigration to the United States as well as the development of the Indo-Guyanese ethnic enclave, “Little Guyana,” located in Queens, New York. This thesis moves beyond the romanticized image of ethnic enclaves in New York City and argues that while perhaps picturesque on the surface, Little Guyana is the result of the fraught history of British colonialism, slavery, and indentured servitude and the sociocultural resilience of the Indo-Guyanese people. Using Little Guyana as a window onto the Indo-Guyanese American experience this thesis explores the ways in which racial tensions in Guyana have taken shape in …

Oscar Wilde's Fiction: Views On Life And Art, Robert C. Derosa

Dissertations and Theses

Oscar Wilde depicts different views on life and art. The stories selected have common themes of wealth (monetary/non-monatary), love, devotion, self-destruction and death:: The Picture of Dorian Gray, "The Happy Prince," "The Devoted Friend," "The Selfish Giant," and "The Rose and the Nightingale." These four fairy tales tie in nicely with Wilde's novel to show the true value of life and art.

Flowers For Abiah: Emily Dickinson's Claim To Live According To Her Own Rules, Carmen M. Santiago

Dissertations and Theses

Emily Dickinson is known for her poems, but her epistolary body of work is as rich and as compelling. Her letters to Abiah Root reveal Dickinson's mind behind the poet and more importantly show the progression and evolution of Dickinson's ideas and sentiments regarding Victorian societal norms.

The Paganist Totem Birds In Slavic Folklore: The Black And The White, Anastasia Radzievska

Dissertations and Theses

It is believed that pagan cosmology once ran strong through the Slavic countries and traces are visible through the passed down folklore that spread through the land. While we talk of animals and their representation in folklore, we usually only refer to the Christian written western folklore, but these pagan born animals stand in strong contrast to them. The Slavic people believed that the world was made of diverse natural forces that shared what the Earth had to offer and worked in unison to protect one another, whereas the Christian belief saw the world as a distinct separation of man …

Blurring The Gender Lines: Margaret Of Anjou's Use Of Gender As Power In Shakespeare’S First Tetralogy, Blythe Abramowitz

Dissertations and Theses

Queen Margaret of Anjou is a uniquely placed character in Shakespeare’s tetralogy beginning with I Henry VI. Margaret is the only female character to be featured in and survive all four plays. From her entrance in I Henry VI, she is a force to be reckoned with; she uses her femininity as a weapon, and as the Henry VI plays continue, her power grows. Her feminine prowess is demonstrated in several ways including her use of her beauty as well as her enchantment of both Suffolk and Henry. She continues to use her femininity to her advantage, and, as …

The Cultural Dual Identity In Cristina Garcia's Dreaming In Cuban And Julia Alvarez's How The Garcia Girls Lost Their Accents, Azahria John-Otway

Dissertations and Theses

Cristina Garcia's Dreaming in Cuban and Julia Alvarez's How the Garcia Girls Lost their Accents are two novels that explore the effects immigration can have on the development of one's identity, respectively. Throughout both novels, it is understood that in order for an immigrant to have a sense of belonging, an exploratory journey of the self must be made. In making this journey, literally and figuratively, the immigrant person begins to appreciate their homeland and immigrated home, thus feeling a sense of belonging and accepting they are of a cultural dual identity.

Edwidge Danticat As Literary Archeologist, Justine A. Browning

Dissertations and Theses

No abstract provided.

Sugar-Derived Oleogels In Cosmetics And Food Applications: A Case Study Of Trehalose- And Mannitol-Based Gelators, Polina Tsupko

Dissertations and Theses

Gels represent an indispensable part of our everyday lives with direct applications in food, medicine, cosmetics and other industries. Amphiphilic molecules have been shown to act as low molecular weight gelators (LMWGs) and are becoming the main focus of several research groups. Their ability to self-assemble into various morphologies from micelles to bilayer sheets, and remain stable due to noncovalent forces responsible for the formation of the 3D network—Self-Assembled Fibrillar Network (SAFiNs)—is in the core of their ability to produce molecular gels. Those amphiphilic molecules capable of adsorbing at the interface and behaving as surface active agents are known as …

Kinetics Of Nesquehonite Nucleation, Halla Rezgui

Dissertations and Theses

During the nucleation of mineral crystals, the particles (atoms and molecules) will be ordered in a crystal lattice and mineral surfaces will develop. The interfacial energy plays important roles in mineral nucleation. The surface energy can be influenced by many factors including temperature, solution chemistry, ion absorptions, and shape/size of nuclei. Previous research studied the effect of solution stoichiometry on the surface energy between nesquehonite and aqueous solution, which strongly relied on simple assumptions (including shape factors). Our research has sought to provide direct observations and quantify modeling on some of these factors affecting the nucleation of nesquehonite. About 72 …

Tropical Cyclone Hazards In Relation To Propagation Speed, Jiehao Huang

Dissertations and Theses

As the population and infrastructure along the US East Coast increase, it becomes increasingly important to study the characteristics of tropical cyclones that can impact the coast. A recent study shows that the propagation speed of tropical cyclones has slowed over the past 60 years, which can lead to greater accumulation of precipitation and greater storm surge impacts. The study presented herein is meant to examine and analyze the relationships that exist between the propagation speed of tropical cyclones, their surface wind strength, displacement angles, and cyclone averaged winds. This analysis is focused on tropical cyclones spanning from 1950-2015 in …

From Neoliberalism To Socialism: Reimagining Socialism In Africa, Kiiru Gichuru

Dissertations and Theses

Abstract. For many scholars, pundits, policy makers, and citizens alike, Africa’s persistent maldevelopment has continued to defy the usual International Monetary Fund (IMF), World Bank, and foreign aid prescriptions that are, at times, peddled as silver bullets to the African conundrum. Beginning in the late 1970s, loans from the IMF and World Bank required African governments to implement certain conditions that were supposed to address public sector mismanagement, illiberal trade policies, low foreign investment, and state development. These austerity measures were designed to usher in an era of financial growth that would enable Africa to join the ranks of developed …

Emergent Women's Global Political Leadership: Progress Despite Constraints, Aoife Meehan

Dissertations and Theses

“Emergent Women’s Global Political Leadership: Progress Despite Constraints” seeks to trace why and how female political leaders emerge at the global level. Evidence points to certain cultural factors, often expressed by laws, constraining or supporting women as they seek political advancement. Data shows women leaders are emerging more and more, though slowly, as political leaders around the world. Reviewing women’s participation and representation regionally and nationally in parliaments, as ministers, and as heads of governments and states confirms that women can and do emerge as political leaders. Finally, learning about and examining women leaders themselves, their style and substance, proves …

Political Representation For Indigenous Peoples In The Andes, Jessica Yepez

Dissertations and Theses

For years, there has been a lack of representation for indigenous peoples in communities, and most importantly in parliament. This is a very common trait in the South American Andes, which houses the largest number of indigenous groups in the continent. This thesis focuses on Ecuador and Bolivia due to their indigenous population and their history, or lack thereof, with indigenous people in parliament. For my hypothesis, I argue that parliamentary representation of indigenous peoples, can help ensure that their rights are protected, and their unique interests are heard and translated into relevant policies, while at the same time preventing …

Understanding How Sequence Differences Among Glutamate Transporters Might Contribute To Their Differential Function In Glutamate Clearance In C. Elegans, Irving Estevez

Dissertations and Theses

In the nervous system, high circuit resolution requires efficient post-signaling clearance of the neurotransmitter. Glutamate-mediated neurotransmission involves the release of glutamate (Glu) into the synaptic cleft by the presynaptic cell and binding to glutamate receptors (GluR) on the postsynaptic cell, leading to activation of a signal transduction cascade. Neurotransmission is eventually terminated by Glu uptake via glutamate transporters (GluT). Inefficient Glu clearance is detrimental to precise rapid signaling, can lead to blurring of circuit resolution by inadvertent Glu spillover to nearby circuits, and may even be neurotoxic. While classical views depict synapses as insulated by glia, recent technological advances show …