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A Study Of Geo-Regional Place-Consciousness In American Literature, Eugene Slepov Sep 2023

A Study Of Geo-Regional Place-Consciousness In American Literature, Eugene Slepov

Dissertations, Theses, and Capstone Projects

The ancient Greek notions of topos, or place, and choros, or region, emerge from a an oral, narrative-based tradition that predates geography. These concepts remind us that that best source of material to study place is to be found in literary fiction. American fiction in particular will give us the evidence by which we can compile a qualitative, experiential understanding of the role of place in people’s lives. This dissertation inquires into the formation of the imaginative constructions that characters put upon place—such as through the process of consolidating and dwelling in places—and the way place puts …


Ways Of Silence And Other Absences In The Music Of George Crumb, Jean-Patrick Besingrand Sep 2023

Ways Of Silence And Other Absences In The Music Of George Crumb, Jean-Patrick Besingrand

Dissertations, Theses, and Capstone Projects

The music of American composer George Crumb (1929-2022) is undeniably singular in the musical landscape. His aesthetic is often characterized by his exploration of timbre, his graphic scores, his use of quotation, his theatricality, and his interest in unusual instruments. This study proposes to take a different approach to Crumb’s aesthetic through the spectrum of silences and other absences. The concept of silence will be broken down and reconstructed through the Japanese concept of ma (間) and of empty spaces. Multiple types of silences and absences will be considered throughout this dissertation, expanding thus the concept of silence not only …


"How" As A Signal Of An Invariant Meaning, Andrew S. Mccormick Sep 2023

"How" As A Signal Of An Invariant Meaning, Andrew S. Mccormick

Dissertations, Theses, and Capstone Projects

This dissertation aims to explain why speakers and writers use how in the communicative contexts in which they do, and its central claim is that how is a signal of one invariant meaning. The form’s diverse communicative contributions can be explained by hypothesizing a single meaning that contributes to different message effects, or contextual interpretations, on different occasions of its use.

The present analysis rests on the crucial distinction in Columbia School (CS) linguistics, the theoretical framework guiding this project, between meaning and message. A meaning is a signal’s invariant semantic contribution, while messages are the context-unique interpretations that …


Does The Apoe-Ε4 Allele Differentially Influence Cognition: A Longitudinal Investigation In Healthy Older Adults At Risk For Alzheimer’S Disease, Aditya Kulkarni Sep 2023

Does The Apoe-Ε4 Allele Differentially Influence Cognition: A Longitudinal Investigation In Healthy Older Adults At Risk For Alzheimer’S Disease, Aditya Kulkarni

Dissertations, Theses, and Capstone Projects

Background: The apolipoprotein E (APOE) ε4 allele is the strongest susceptibility factor for sporadic, late-onset, Alzheimer’s disease (AD). However, not all persons who carry the ε4 allele show significant cognitive decline, and thus do not progress to dementia. The impact of the ε4 allele on memory decline has been documented primarily in populations already demonstrating cognitive impairment (i.e., those with mild cognitive impairment or dementia), with fewer investigations completed in baseline healthy older adults. Investigations of the ε4 allele and its influence on non-memory domains are also sparse in the literature. Furthermore, these cognitive investigations are typically cross-sectional and …


You Don’T Even Need The Ghosts: A Writer’S Look At The Turn Of The Screw, Andrea M. Schenkel Sep 2023

You Don’T Even Need The Ghosts: A Writer’S Look At The Turn Of The Screw, Andrea M. Schenkel

Dissertations, Theses, and Capstone Projects

The novella Turn of the Screw by Henry James was first published in 1898 as a serialized novel in Collier's Magazine. The short novel is characterized by its concise language. James chooses words carefully and consciously. The linguistic compression forces the reader to deal intensively with the main protagonists of the novel: the Governess, the children, Miles and Flora, and Mrs. Grose. Nothing is as it seems. James aims to challenge the reader by forcing them to constantly question what they read.

Countless essays have been written about the text since the novel was published. The figures, especially those …


Characterization And Modulation Of The Emergent Material Properties Of Biomolecular Condensates, Alfredo Vidal Ceballos Sep 2023

Characterization And Modulation Of The Emergent Material Properties Of Biomolecular Condensates, Alfredo Vidal Ceballos

Dissertations, Theses, and Capstone Projects

The discovery of membraneless organelles has revolutionized the field of cell biology and our understanding of cell compartmentalization. These organelles lack a distinct phospholipid bilayer and interact with the cytoplasm mediated by a liquid-liquid interface. The emergent properties and characterization of these organelles are essential for decoding the mechanisms underlying their function and dysfunction. In this thesis, we focus on two reconstituted in-vitro model systems of protein condensates and advance current methodology in order to address these fundamental questions. The first model system examined is the neuronal granule protein Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein, that aids …


Konohana, Jean-Patrick Besingrand Sep 2023

Konohana, Jean-Patrick Besingrand

Dissertations, Theses, and Capstone Projects

Konohana is a concerto for clarinet and ensemble written for the ensemble Court-Circuit in the context of the Composition Academy Philippe Manoury and the Musica Festival in Strasbourg. Konohana (Konohanasakuya-hime) is the goddess of Mount Fuji and the princess of cherry blossoms. She is associated with the sakura and the ephemeral beauty of its blooming. This piece is inspired by the symbolism of the cherry blossom as well as the socio-cultural aspect of the blooming flowers. From the clarinet, contrapuntal lines emerge and progressively densify the instrumental texture like rhizomes. This densification is interrupted by the presence of « inserts …


Social And Cultural Processes That Impact Physical Activity Among South Asian Americans Managing Hypertension: A Mixed Methods Study, Sugandha Gupta Sep 2023

Social And Cultural Processes That Impact Physical Activity Among South Asian Americans Managing Hypertension: A Mixed Methods Study, Sugandha Gupta

Dissertations, Theses, and Capstone Projects

Cardiovascular disease (CVD), the number one cause of death in the U.S., disproportionately affects South Asian Americans (SAAs). Physical activity is a modifiable health behavior that can reduce cardiovascular risk. Health behaviors, such as physical activity, occur within specific social and cultural contexts and are influenced by multiple factors at multiple levels of the social ecological model. This dissertation aimed to provide a rich, culturally-informed understanding of the factors at multiple levels – individual, interpersonal, and cultural –associated with physical activity among SAAs at risk for CVD. A sequential exploratory mixed methods approach was employed to examine social and cultural …


How Smoking Became A Moral Issue: A Complex Systems Perspective On Moralization, Matthew Vanaman Sep 2023

How Smoking Became A Moral Issue: A Complex Systems Perspective On Moralization, Matthew Vanaman

Dissertations, Theses, and Capstone Projects

When something is morally wrong, it is in the moral domain; when something becomes morally wrong, it is moralized. But how do we know when something is in the moral domain, and how can we tell whether something is becoming moralized? The empirical study of morality, or a given person’s judgment of what constitutes moral virtue or vice, has historically approached these questions through one of three theoretical perspectives: cognitivism, which argues that people primarily or mostly use effortful thought to judge right from wrong; emotivism, which sees these judgments as flowing from emotion; and dual-process models, which …


A Difference Of One's Own: Race, Sex, Modernism, Ryan L. Tracy Sep 2023

A Difference Of One's Own: Race, Sex, Modernism, Ryan L. Tracy

Dissertations, Theses, and Capstone Projects

“A Difference of One’s Own” demonstrates that deconstructive conceptions of race lie at the heart of the modernist canon’s experimental representations of selfhood. Drawing on recent and canonical scholarship in Modernist Studies, Black Studies, Deconstruction, Queer Theory, Critical Theory, and Feminist Studies, I look at moments in modernist-era literature where the need to represent racial blackness, whether as a descriptor that defines one’s self-identity or the identity of another person, fails to draw a coherent line of difference between people, communities, selves, and importantly, the literatures that are thought to adhere to hard and fast racial distinctions. “Part I: …


Disordered Protein Aggregates Are Linked To Changes In The Histone Post-Translational Modification Landscape In Disease And Non-Disease Models, Samantha Cobos Sep 2023

Disordered Protein Aggregates Are Linked To Changes In The Histone Post-Translational Modification Landscape In Disease And Non-Disease Models, Samantha Cobos

Dissertations, Theses, and Capstone Projects

Proper protein folding is a delicate balance that is crucial for normal biological function. In mammals, protein misfolding and aggregation leads to loss of function of the original protein while in many cases being associated with neurodegenerative diseases, eventually leading to death of the organism. In yeast however, the aggregated prion state is associated with positive cellular outcomes, and cells can switch between the [PRION+] and [prion-] states. Understanding the factors that lead to changes in prion state conformation in yeast could lead to novel insight into the conditions controlling misfolding by neurodegenerative proteinopathies. We believe that by studying the …


The Promise Of Universalism Deferred: Political Economy Of Social Policy In 21st Century Latin America, Juan C. Ferre Sep 2023

The Promise Of Universalism Deferred: Political Economy Of Social Policy In 21st Century Latin America, Juan C. Ferre

Dissertations, Theses, and Capstone Projects

In the first decade and half of the 21st century, most Latin American countries experienced a long-overdue reduction in income inequalities and significant social policy expansion. While this welfare expansion has been widely documented, scholars have paid less attention to the persistent or increasing segmentation: inequalities in transfers and in the quality of services across population groups continued unabated. This dissertation employs mixed-methods to respond to the following questions: have governments in Latin America, and Left governments in particular, made significant progress toward universal social policy?

For 17 Latin American countries in the period 2000-2020, I measure three dimensions …


Soundness And Completeness Results For The Logic Of Evidence Aggregation And Its Probability Semantics, Eoin Moore Sep 2023

Soundness And Completeness Results For The Logic Of Evidence Aggregation And Its Probability Semantics, Eoin Moore

Dissertations, Theses, and Capstone Projects

The Logic of Evidence Aggregation (LEA), introduced in 2020, offers a solution to the problem of evidence aggregation, but LEA is not complete with respect to the intended probability semantics. This left open the tasks to find sound and complete semantics for LEA and a proper axiomatization for probability semantics. In this thesis we do both. We also develop the proof theory for some LEA-related logics and show surprising connections between LEA-related logics and Lax Logic.


Magnetically-Driven Therapeutic Agents Delivery System Using Iron Oxide Nanocages And Enhancement Of Exosome Secretion, A Potential Biological Drug Delivery Carrier, Min A Kang Sep 2023

Magnetically-Driven Therapeutic Agents Delivery System Using Iron Oxide Nanocages And Enhancement Of Exosome Secretion, A Potential Biological Drug Delivery Carrier, Min A Kang

Dissertations, Theses, and Capstone Projects

Nano-scale particles have attracted research attention due to their differences in properties such as penetration, circulation, and toxicity compared to bulk materials. This thesis mainly focused on using 20 nm iron oxide nanoparticles as siRNA delivery carriers under the alternating magnetic field and the development of a method to amplify the secretion of 150 nm exosomes from the cells, which could potentially use as a biological drug carrier.

Chapter 2 discusses a magnetically driven nanoparticle therapeutic agent delivery system, which efficiently modified the gene expression post-transcriptionally. In this work, we examined whether the caged-shaped 20nm iron oxide nanoparticles (IO-nanocages) can …


Remote Sensing Characterization Of Ecosystem Structure And Functional Types To Inform On Biodiversity Conservation In The Lowland Chocó Rainforest, Derek Tesser Sep 2023

Remote Sensing Characterization Of Ecosystem Structure And Functional Types To Inform On Biodiversity Conservation In The Lowland Chocó Rainforest, Derek Tesser

Dissertations, Theses, and Capstone Projects

This dissertation focuses on the utilization of remote sensing techniques to characterize ecosystem structure and functional types to inform on biodiversity conservation. This work is motivated by a guiding hypothesis that increased degradation of tropical forest biodiversity due to human activity results in in measurable changes in ecosystem processes that can be detected using remote sensing technologies. Throughout this dissertation, testing of aspects of this hypothesis involve comparing areas with varying degrees of human-induced degradation in a biodiverse tropical ecoregion, the lowland Chocó rainforest of Ecuador. Remote sensing data is used to evaluate changes in vegetation structure, thermal regimes, and …


Metabolic Control Of Proliferation And Differentiation In Oligodendrocytes, Sami Sauma Sep 2023

Metabolic Control Of Proliferation And Differentiation In Oligodendrocytes, Sami Sauma

Dissertations, Theses, and Capstone Projects

Oligodendrocytes (OLs) are specialized cells whose membrane extension, called myelin, wraps the axons providing insulation, trophic and metabolic support, and is essential for proper functioning of the central nervous system. Inappropriate myelin formation, damage or dysfunction of oligodendrocytes has been identified in several neurological disorders and often precedes the loss of neuronal cells. OLs derive from proliferating oligodendrocyte progenitor cells (OPCs), which exit from the cell cycle and undergo a series of transcriptional and epigenetic events, including histone post-translational modifications, resulting in morphological and functional changes. Our lab previously identified elevated levels of histone acetylation in proliferating OPCs during the …


Synthesis And Characterization Of Polymer-Based Complex Nanomaterials, Prashun G. Roy Sep 2023

Synthesis And Characterization Of Polymer-Based Complex Nanomaterials, Prashun G. Roy

Dissertations, Theses, and Capstone Projects

The original research work in this dissertation is about the use of polymers in two significantly important areas. One involves creating mesoporous silica materials with various morphologies using a mixed Pluronic surfactant system made up of two poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) surfactants, one of which contains long hydrophilic (PEO) blocks and the other has a significantly higher proportion of hydrophobic PPO . In addition, a glucose responsive core-shell type microgel was also developed for shifting the glucose responsive volume phase transition by using polymeric nanomaterials.

Chapter 1 of the dissertation discussed some historical background of synthesis and uses of …


New York City Yoga Studios Archive (Nycysa), Allison Daugila Sep 2023

New York City Yoga Studios Archive (Nycysa), Allison Daugila

Dissertations, Theses, and Capstone Projects

NYC Yoga Studios Archive is a digital archive meant to preserve the histories of yoga workers participating in the NYC Yoga industry in the years before, during, and following the COVID-19 pandemic (January 2020–July 2023). In March 2020, the World Health Organization commissioned that gathering in groups in indoor settings was one of the highest risk activities anyone could participate in, which almost immediately cast fitness venues as a COVID-19 hotspot. The circumstance of New York City being the United States’ most populous city per square mile meant that most yoga establishments in the five boroughs remained closed for in-person …


Fifteenth-Century Sienese Art In Its International Setting: A Case Study Of Cross-Cultural Exchange In Italy And Beyond, Maria Lucca Sep 2023

Fifteenth-Century Sienese Art In Its International Setting: A Case Study Of Cross-Cultural Exchange In Italy And Beyond, Maria Lucca

Dissertations, Theses, and Capstone Projects

Scholars often frame the Republic of Siena as isolationist and inward-looking, yet from its beginning in 1262 the city-state was internationally vital, sending artists to work in foreign cities and calling upon foreign artists to do significant work in Siena. Although Siena temporarily retreated from this internationalism to a period of relative cultural autonomy in the mid-Trecento, in the early Quattrocento it re-opened the gates of its medieval walled city to artistic interchange between Sienese and Florentine sculptors, setting in motion the dramatic shift that occurred in the mid-Quattrocento. Sienese sculptors embraced the Renaissance artistic humanism flourishing in Florence and …


Observers' Perceptions Of Rapport In Accusatorial Interrogations, Gabriela Rico Sep 2023

Observers' Perceptions Of Rapport In Accusatorial Interrogations, Gabriela Rico

Dissertations, Theses, and Capstone Projects

Rapport is widely regarded as a necessary precondition for interrogations and is thought to lay the foundation for the success of later interrogation techniques. In accusatorial contexts in which suspects are often resistant to disclose potentially self-incriminating information, rapport enables interrogators to gain the suspect’s trust, respect, and cooperation. Although the specific psychological mechanisms by which rapport achieves these effects are largely understudied, rapport-building techniques resemble principles of social influence (Goodman-Delahunty & Howes, 2014), specifically persuasion. Techniques such as establishing common ground, engaging in active listening, demonstrating empathy, and disclosing personal information may serve as impression management strategies, which allow …


Between Concealment And Revelation: Oblique Modes Of Female Self-Expression In Eighteenth-Century Literature And Life Writing, Sophia N. Sunseri Jun 2023

Between Concealment And Revelation: Oblique Modes Of Female Self-Expression In Eighteenth-Century Literature And Life Writing, Sophia N. Sunseri

Dissertations, Theses, and Capstone Projects

This dissertation examines the social landscape of eighteenth-century Britain as one that was especially inimical to women and analyzes instances in literature and life writing in which female characters and historical figures negotiated the various restrictions they faced in social settings by “hiding in plain sight” and devising alternative strategies by which they might be seen and heard: by engaging in what I am referring to as a play between concealment and revelation. I explore texts where female characters who have been silenced and forced to conceal their presence in social situations craft diffuse strategies through which they express themselves …


Statistical And Biological Analyses Of Acoustic Signals In Estrildid Finches, Moises Rivera Jun 2023

Statistical And Biological Analyses Of Acoustic Signals In Estrildid Finches, Moises Rivera

Dissertations, Theses, and Capstone Projects

Acoustic communication is a process that involves auditory perception and signal processing. Discrimination and recognition further require cognitive processes and supporting mechanisms in order to successfully identify and appropriately respond to signal senders. Although acoustic communication is common across birds, classical research has largely disregarded the perceptual abilities of perinatal altricial taxa. Chapter 1 reviews the literature of perinatal acoustic stimulation in birds, highlighting the disproportionate focus on precocial birds (e.g., chickens, ducks, quails). The long-held belief that altricial birds were incapable of acoustic perception in ovo was only recently overturned, as researchers began to find behavioral and physiological evidence …


Beyond The Songs On The Vistula: Chopin And Poland, A Mythical Construction, Juan Carlos Fernandez-Nieto Jun 2023

Beyond The Songs On The Vistula: Chopin And Poland, A Mythical Construction, Juan Carlos Fernandez-Nieto

Dissertations, Theses, and Capstone Projects

Poland and Chopin are two concepts that cannot be separated, for they form an entity of their own. However, the story of both subjects has often been manufactured to offer a view of the patriotism and the connection of Chopin with his country, which promoted the creation of the nation. At the same time, the circumstances that propitiated the rise of nationalism and the social unrest that ended with World War I were the same that promoted the myth of Chopin. Therefore, this research is focused on the analysis of the facts and the context that created the myth of …


Beat Construal, Tempo, Metric Dissonance, And Transgressing The Groove In Heavy Metal, Drew Fleming Jun 2023

Beat Construal, Tempo, Metric Dissonance, And Transgressing The Groove In Heavy Metal, Drew Fleming

Dissertations, Theses, and Capstone Projects

This dissertation explores the relationship between the metric practices of heavy metal and the elements and processes of the musical quality known as “groove.” Although heavy metal is not often expressly associated with groove per se, it occupies a historical position within the stylistic milieu for which groove music has established the primary, referential conditions. In order to uncover this connection, then, I begin with an analysis of groove in relation to established groove-music styles, defining it as an embodied and encultured knowledge of a set of cognitive, social, kinetic, aesthetic, and musical behaviors extending in practice from African-American popular-music …


Propensity Score Analysis And Machine Learning: A Comparison And Application To Post-Secondary Education Data, Khudodod Khudododov Jun 2023

Propensity Score Analysis And Machine Learning: A Comparison And Application To Post-Secondary Education Data, Khudodod Khudododov

Dissertations, Theses, and Capstone Projects

Estimation methods to identify the causal relationships between dependent and independent variables are fundamental to social science research. For social workers, these methods provide crucial knowledge about different factors' complex relationships with a particular issue. Such knowledge helps social workers be better micro, mezzo, and macro change agents.

Different causal estimation methods exist, from randomized controlled studies to methods involving observational studies. In observational studies, which is the focus of this dissertation, participants self-select into intervention. This behavior makes causal estimation more challenging. Since participants self-select into intervention or treatment, there are observed and unobserved differences between participants in the …


Social Capital, Social Support, And Subjective Well-Being Of Older Adults In Ghana And South Africa: The Moderating Role Of Country, Paul K. Ayernor Jun 2023

Social Capital, Social Support, And Subjective Well-Being Of Older Adults In Ghana And South Africa: The Moderating Role Of Country, Paul K. Ayernor

Dissertations, Theses, and Capstone Projects

The study objective is to test the influence of social capital and social support on subjective well-being. It is also interested in the combined effects of macro-level factors as encapsulated in a macro-level variable - country that exerts influence on micro-level variables such as social capital and social capital. Additionally, the present study is one of the earliest studies to begin to assess the effect of older adults' perception of neighborhood happiness or sadness on the subjective well-being of older adults in a sub-Saharan Africa context.

Data comes from wave 1 of a multi-country Study on Global Ageing and Adult …


Multi-Target Ligand-Guided Selection (Ligs) Against B-Cell Specific Antigens Expressed In A Single Lymphoma Cell Population, Nicole B. Williams Jun 2023

Multi-Target Ligand-Guided Selection (Ligs) Against B-Cell Specific Antigens Expressed In A Single Lymphoma Cell Population, Nicole B. Williams

Dissertations, Theses, and Capstone Projects

Nucleic acid ligands called aptamers are single-stranded DNA or RNA molecules which fold into functional three-dimensional structures to facilitate their target binding with high affinity and specificity. The method used to generate aptamers is an in vitro process called Systematic Evolution of Ligands by Exponential enrichment (SELEX). A variant of SELEX, cell-SELEX has been used to select aptamers against cell-surface proteins in their native state. We recently introduced a novel method called Ligand-Guided Selection (LIGS) to identify aptamers against cell-surface markers. Herein, we expanded LIGS method into a multiplexing platform to partition multiple aptamers against B-cell-specific antigens, CD19 and CD20, …


International Student Orientations: Indian Students At American Universities Around The Turn Of The Twentieth Century, Param S. Ajmera Jun 2023

International Student Orientations: Indian Students At American Universities Around The Turn Of The Twentieth Century, Param S. Ajmera

Dissertations, Theses, and Capstone Projects

This dissertation examines the writings and experiences of five Indian international students in the United States during late nineteenth and early twentieth centuries. By drawing attention to these students, I attend to the ways in which notions of freedom, progress, and inclusivity associated with American higher education, and liberalism more generally, are related to structures of racialized and colonial dispossession in India. I build these arguments by reading archival sources such as university administrative records, student publications, personal and official correspondence, as well as understudied aesthetic works, such as memoirs, travel narratives, essays, doctoral dissertations, and public lectures. These historical …


Transcranial Direct Current Stimulation Studies Investigating The Role Of The Dlpfc In Memory And Metamemory, Casey M. Imperio Jun 2023

Transcranial Direct Current Stimulation Studies Investigating The Role Of The Dlpfc In Memory And Metamemory, Casey M. Imperio

Dissertations, Theses, and Capstone Projects

Metamemory, broadly defined as knowledge about one’s own memory, is thought to consist of two separate processes, monitoring, the ability to assess the contents of your own memory, and control, altering behavior in service of memory, that work together to aide in encoding and retrieval processes. Prior work has shown that metamemory monitoring accuracy can be improved in a semantic memory task via high-definition transcranial direct current stimulation (HD-tDCS), a form of non-invasive brain stimulation, over the left dorsolateral prefrontal cortex (DLPFC). Over three experiments, the current dissertation sought to replicate and extend this work by: 1) testing the effects …


The Impact Of Political Affiliation On Performance Judgements, Kajal Patel Jun 2023

The Impact Of Political Affiliation On Performance Judgements, Kajal Patel

Dissertations, Theses, and Capstone Projects

The ability to keep politics out of daily organizational life has been severely eroded. With the increasing polarization in American politics and ubiquitous use of social media to express political positions, negative attributions are being made of individuals holding different political positions. Due to its pervasive nature, it is important to understand how politics impacts organizationally relevant decisions that supervisors and others make as a routine part of their jobs. This study examined the influence of similarity and dissimilarity in political affiliation between a rater and ratee on performance judgments. To examine the relationship between political affiliation similarity and performance …