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Nutritional Status Of Patients With End Stage Liver Disease: An Outpatient Assessment, Anna Marie Cumming-Browne Hefner Phd, Msn, Cpnp, Rn

Dissertations

Cirrhosis is the 12th leading cause of death in the United States. It is well documented end stage liver disease drives a patient to a catabolic state thus depleting them of essential nutrients. Malnutrition is often unrecognized and untreated in outpatients. Though BMI, nutritional intake, anthropometric measurements have been used in clinical trials, there still remains no standard nutritional assessment. The purpose of this dissertation was to (1) identify the incidence of malnutrition in patients with compensated and decompensated liver disease utilizing defined nutritional parameters (Subjective Global Assessment, anthropometric measurements, hand grip strength, and laboratory values) and (2) correlate with …

Risk-Appropriate Maternal Care: Identifying Risk Factors That Effect Maternal Outcome, Lucy R. Van Otterloo Phd, Msn, Rnc, Cns

Dissertations

Although maternal deaths are the most tragic of obstetric events it continues to be a rare event. Maternal morbidity, on the other hand, is increasing and poses a greater impact on the economic, psychological, and physical health of the woman and her family, yet it has not been the focus of measurement or research since there is no systematic collection of data available. As complications increase, the likelihood of adverse maternal outcomes such as longer postpartum stays due to the need for more extensive care will also increase. Nurses are being challenged to use their knowledge and skills to identify …

Performance Assessment For Quality Teaching: Three Critical Variables For Measuring And Improving Teaching And Learning, Kathleen L. Gallagher Phd

Dissertations

While outstanding teachers are any school system's most important investment, assessing the quality of instructional practice has proven to be an ongoing challenge for the profession. Despite assertions that effective teachers are the single most important school-related factor responsible for increased learning, no teacher's employment is dependent on their performance in the classroom or the quality of instruction that they provide. This problem has fueled a growing mistrust in school districts nationwide, specifically in the area of teacher evaluation. One possible explanation is that the profession lacks the scaled level of expertise needed to evaluate instruction consistently and in a …

Exploring The Paradoxical Role And Experience Of Fallback In Developmental Theory, Valerie Townsend Livesay Phd

Dissertations

Constructive-development and stage development theory, which posits that individuals move through different stages or action logics throughout life, has been the foundation for several models of human transformation. The literature on the leading stage theories indicates that research has focused on exploring stages and their behavioral correlates, but little work has been done on how individuals move between stages. Stage theory has primarily been conceived of as a linear and unidirectional transition from one stage to the next, which encompasses earlier stages, however emerging research has revealed that stage transition may be more fluid and bi-directional than originally thought and …

Diversification And Coexistence In The Madagascar Olive (Noronhia, Oleaceae), Cynthia Hong-Wa

Dissertations

The long-isolated island of Madagascar provides a suitable setting for studying species diversification, with most groups of organisms there both radiating and showing a high level of endemism. Noronhia is one of these groups and represents the most successful radiation of the olive family (Oleaceae) in Madagascar, with ca. 80 species. In this study, using plastid and nuclear DNA sequences obtained from a comprehensive sampling both within Noronhia and the family, I show that Noronhia, together with Indian Ocean species of Chionanthus, form a monophyletic clade sister to African Chionanthus. The diversification of Noronhia followed a likely Cenozoic dispersal from …

Comparision Of Alternatively Certified And Traditionally Certified Missouri High School Science Teachers’ Perceptions Of Self-Efficacy During The Induction Period, Linda Gaither

Dissertations

Sixty percent of America’s teachers choose traditional baccalaureate programs while the remaining choose one of several alternative pathways. While certification/training is certainly important to preparing effective teachers, other research indicates that teacher efficacy serves as the foundation of teacher behaviors and classroom practice. The purpose of this study (N = 94 induction high school science teachers) was to determine the relationships between certification pathway and opportunities to observe modeling; between years of experience and personal teaching efficacy; and teachers’ perceptions of what characteristics/ experiences best explain personal teaching efficacy. The Teacher Sense of Efficacy Scale was used in an on-line …

Student Thoughts And Perceptions On Curriculum Reform, Douglas D. Vanderjagt

Dissertations

The purpose of this qualitative case study was to examine how students experience and respond to Michigan’s increased graduation requirements. The study was conducted in a large, suburban high school that instituted a change to a trimester system in response to the state mandate. A criterion-based sample of 16 students, both college bound and non-college bound, participated in one-on-one interviews regarding their knowledge about, their understanding of, and their experience with the new Michigan Merit Curriculum, and how this increase impacted the student participants’ high school academic choices and/or postsecondary plans. Additionally, this study engaged focus groups of one or …

Factors Influencing Student Motivation Within Two University-Offered Physical Activity Classes, Chad A. Grabau

Dissertations

No abstract provided.

Trauma And Post-Traumatic Stress Disorder In Therapeutic Day School Students: Prevalence In This Population And Effective Treatment Programs, Monica Roberts

Dissertations

This survey-based, comparative study investigated the percentage of students at a suburban Chicago therapeutic day school who meet criteria for clinically significant levels of PTSD as compared to students in a general education setting. The directional hypothesis was that students placed at therapeutic day schools have a higher prevalence of PTSD than a general population of students. The method used was a survey assessment called the Child PTSD Symptom Scale (CPSS) given to 16 students at a suburban Chicago therapeutic day school. These CPSS scores were analyzed and statistically compared to CPSS scores of an already published study with students …

Artificial Immune Systems And Particle Swarm Optimization For Solutions To The General Adversarial Agents Problem, Jeremy Mange

Dissertations

The general adversarial agents problem is an abstract problem description touching on the fields of Artificial Intelligence, machine learning, decision theory, and game theory. The goal of the problem is, given one or more mobile agents, each identified as either “friendly" or “enemy", along with a specified environment state, to choose an action or series of actions from all possible valid choices for the next “timestep" or series thereof, in order to lead toward a specified outcome or set of outcomes. This dissertation explores approaches to this problem utilizing Artificial Immune Systems, Particle Swarm Optimization, and hybrid approaches, along with …

Compositional And Structural Analysis Of Nitrogen Incorporated And Ion Implanted Diamond Thin Films, Elias James Garratt

Dissertations

Significant progress in area of nano-structured thin film systems has taken place in recent decades. In particular, diamond thin film systems are being widely studied for their wear resistant, optical and electronic properties. Of the various methods researchers use to modify the structure of such films, three techniques in particular are of interest due to their versatility: modification of the growth atmosphere, growth on metalized substrates, providing an interfacial layer, and modification through post-growth ion implantation. The aim of this study is to investigate the effects each has to the structure and composition of elements. Different techniques are applied in …

Counselor Educator Knowledge, Experience, Attitudes And Beliefs Toward Complementary And Alternative Medicine, Jennifer Mills Langeland

Dissertations

Following growing public interest and widespread use, many health professions have begun to explore the attitudes toward, knowledge of and experience with complementary and alternative medicine (CAM) of the various stakeholders within their professions. This foundational information has enabled disciplines such as medicine, nursing, psychology, and marriage and family therapy to take a closer look at how students, patients, clients, and faculty think about and utilize CAM and its relevance to their professions. Surveying the practices and attitudes of stakeholders has been an important starting point for professions undertaking the task of integrating these practices into training programs.

This study …

Exercise Alters Glial Cell Line-Derived Neurotrophic Factor (Gdnf) Protein Content In The Spinal Cord, Monica Janine Mccullough

Dissertations

Neurotrophic factors may play a role in exercise-induced neuroprotective effects; however, it is not known if exercise mediates changes in glial cell line-derived neurotrophic factor (GDNF) protein levels in the spinal cord. The aim of the studies described herein was to determine if exercise alters GDNF protein expression in the lumbar spinal cord of healthy and diseased animals. The lumbar spinal cord was analyzed from adult rats aged 6-, 12-, 18- and 24-months, and from transgenic amyotrophic lateral sclerosis (ALS) mice and wild-type mice aged 3 months. Animals had undergone either forced wheel running, voluntary wheel running or swimming for …

Localized Surface Plasmon Resonance Induced Structure-Property Relationships Of Metal Nanostructures, Subramanian Vilayurganapathy

Dissertations

The confluence of nanotechnology and plasmonics has led to new and interesting phenomena. The industrial need for fast, efficient and miniature devices which constantly push the boundaries on device performance tap into the happy marriage between these diverse fields. Designing devices for real life application that give superior performance when compared with existing ones are enabled by a better understanding of their structure-property relationships. Among all the design constraints, without doubt, the shape and size of the nanostructure along with the dielectric medium surrounding it has the maximum influence on the response and thereby the performance of the device. Hence …

Breaking The Boundaries: Decision Factors That Lead Male Students To Enroll In Associate Degree Nursing Programs In Illinois Community Colleges, Leandro Alcovendaz Resurreccion

Dissertations

Male nurses are but a small percentage of the total nurse population in the United States, and most certainly have potential to increase in numbers if the profession appeared more attractive as a career option for men. The purpose of this research was to discover the decision factors used by males that led them to enroll in Associate Degree nursing programs in Illinois community colleges. To set the background and context, the study explored the history of community colleges and that of nursing. Included was nursing as a profession, nursing in the United States, the country’s impending nursing shortage and …

Engineered Interfaces And Nano-Scale Thin Films For Solid Oxide Fuel Cell Electrolytes, Manjula I. Nandasiri

Dissertations

Solid state electrolytes with high oxygen ionic conductivity at low temperatures are required to develop cost effective and efficient solid oxide fuel cells. This study investigates the influence of engineered interfaces on the oxygen ionic conductivity of nano-scale multilayer thin film electrolytes. The epitaxial Sm₂O₃ doped C_eO₂ (SDC) and Sc₂O₃ stabilized ZrO₂ (ScSZ) are selected as the alternative layers for the proposed multilayer thin film electrolyte based on the optimum structural, chemical, and electrical properties reported in the previous studies. The epitaxial SDC(111)/ScSZ(111) multilayer thin films are grown on high …

Synthesis And Characterization Of New Light Emitting Probes For Sensitive Detection Of Bio-Molecules And Live Cells, Shyamala Pravin Pillai

Dissertations

A variety of contemporary analytical platforms in technical and biological applications take advantage of labeling the objects of interest with fluorescent or luminescent tracers. Luminescent tracers take advantage of the unique property of some lanthanide metals to absorb and emit light. Long lifetime of lanthanide emission allows temporal gating of the signal, which avoids the short-lived background of interfering sample components. This property in combination with large Stokes shift contributes to extreme sensitivity of detection (ca. 10^-13-10^-14 M), which makes lanthanide-based probes suitable for large variety of challenging tasks ( e.g., intracellular detection of single DNA/RNA, or …

Separation Of Various Organic-Organic And Aqueous-Organic Solutions Via Pervaporation, John Tang

Dissertations

Pervaporation, an energy saving separation process, can be useful in pharmaceutical processing. However, the organic solvents involved in pharmaceutical product synthesis are chemically demanding; very few polymers are able to withstand them. An ideal membrane would be polymeric having a high thermal, chemical and mechanical stability. Such a membrane is made of a copolymer of polydimethyldioxole and tetrafluoroethylene known as PDD-TFE of the CMS-3 variety with a very high free volume. This novel membrane is used to separate a variety of organic-organic and aqueous-organic mixtures. An earlier study based on water-ethanol-isopropanol has shown evidence that the membrane selectivity may be …

Modeling Cell Proliferation In A Perfusion Tissue Engineering Bioreactor, Jeffrey Vincent Pohlmeyer

Dissertations

In this dissertation we develop a comprehensive model to simulate a tissue engineering experiment. The experiment takes place in a bioreactor in which a cell seeded porous scaffold is placed, and the scaffold experiences a perfused flow of a nutrient-rich culture medium. The goal of the model is to assist experimentalists in evaluation of different parameter scenarios as the time needed to simulate an experiment is significantly less than the time needed for the experiment itself. We provide the full two-dimensional model development, as well as investigation into possible variations of specific model choices, and we demonstrate the robustness and …

Particle Engineering Via Surface Modification During Micronization For Pharmaceutical Applications, Xi Han

Dissertations

Improving the dissolution rate of Biopharmaceutics Classification System (BCS) class II drugs is an important research area. Micronization which can increase the specific surface area is a promising method to improve the dissolution rate. Micronization alone, however, can lead to downstream processing problems related to poor flow and dispersion properties. The importance of the flowability of pharmaceutical powders is well-documented in the literature. It is, therefore, important to develop a method that can simultaneously overcome these processing issues and allow for micronizing the API. In this work, dry particle coating technique is investigated in the context of micronizing API powders …

Development Of Luminescent Probes For Ultrasensitive Detection Of Biopolymers, Their Complexes, And Living Cells, Laura A. Wirpsza

Dissertations

New luminescent probes with enhanced brightness convenient for bioconjugation were synthesized and tested in major biological applications including the detection of nucleic acids and living cells. The first project used luminescent lanthanide ion probes that take advantage of hyper-sensitive acquisition of their long-lived emission signal in time- resolved mode, which avoids short-lived background fluorescence of the medium. Two model carbostyril fluorophores (cs 124-CH₃ and cs 124-CF₃) were modified by inclusion of two spacers (diamino and bi-phenyl) for the attachment of amine and thiol reactive cross-linking groups. In this project, time-resolved measurements are presented for spectroscopy and microscopy. …

Fabrication And Evaluation Of A Collagen-Based Fiber-Gel Three-Dimensional Construct For Peripheral Nerve Repair, Mevan Lakmal Siriwardane

Dissertations

Nerve regeneration following a peripheral nerve injury often relies on growth cone- mediated guidance and the presence of Schwann cells to support the regenerating axons and remyelinate portions of denervated nerve pathways. The emphasis of this work is to develop a synthetic nervous tissue construct that contains similar basal lamina or extracellular matrix to peripheral nerve in order to achieve a level of effectiveness in nerve repair and future peripheral nerve regeneration applications. To this end, three- dimensional nervous tissue constructs consisting of type I collagen are fabricated into a composite biomaterial scaffold to promote contact-guided growth of neuronal and …

Astrocytes Modulate Microglial Phenotype And Dendritic Cell-Like Properties, Nischal K. Padala

Dissertations

Microglia are the resident immune cells of the CNS. In the healthy CNS, they express negligible levels of MHC II molecules as well as co-stimulatory molecules CD40, CD80 and CD86 necessary for antigen presentation to and activation of T cells. Co-stimulatory molecule expression can be induced in isolated microglia in vitro by sequential treatment with granulocyte monocyte colony-stimulating factor (GM-CSF) followed by lipopolysaccharide (LPS). Upon such treatment, they become mature dendritic cells (DCs), capable of activating T cells. However, microglia are not isolated in life, but rather exist in an environment enriched by other cells, notably astrocytes.

Therefore, to determine …

Mathematical Modeling Of Heavy Metals Diffusion And Removal From Cylindrical Cement Forms Coated With Bio-Film, Mojdeh Tabatabaie

Dissertations

A mathematical model is developed to predict bioleachi ng of heavy metals from long cylindrical shape cementitious samples. In this model, the metal concentration difference within the solid and its surface is considered as the main driving force for transport of metals to the surface of a sample at a given temperature and pressure. Fick’s first and second law are applied to explain the motion of contaminants in a long and uniform cylindrical solid. In addition, the model considers Michaelis-Menten type kinetics, a special case of the widely accepted Langmuir-Hinshelwood reaction mechanism, at the surface of the encapsulating cylinder. The …

Voices From Behind Bars: A Working Alliance?, Mariaimee Gonzalez

Dissertations

Prisons have become a primary location for mental health services, yet little research has been done to investigate the clinical relationships experienced by a growing population of female inmates. This qualitative study was based upon intersectional theory and explored the experiences of 12 female inmates through in-depth interviews about receiving mental health services in prison and the quality of the working alliance with mental health professionals. Additionally, suggestions for improving mental health services in the prison system are documented. Through 12 semi-structured interviews the researcher listened to narratives of these participants and their mental health journeys. Using open and axial …

Perceived Macrolevel Social Pressure Regarding Racial Identification And The Biracial Experience, John Thomas Nanney

Dissertations

Contemporary multiracial theory posits that racial identifications are a product of perceptions of the macrolevel social environment in which they are embedded (Renn, 2003; Rockquemore, Brunsma, & Delgado 2009; Rockquemore, Laszloffy, & Noveske, 2006; Root, 1996; Root, 2003). This conceptualization of the multiracial experience suggests that research attention should begin examining the specific macrolevel factors that influence the process of biracial identification (Rockquemore et al., 2009). To date, however, relatively little empirical research has done so. The present study sought to examine the extent to which perceived macrolevel social pressure regarding racial identification impacts the multiracial experience. Structural equation modeling …

A Methodology For Coronary Stent Product Development: Design, Simulation And Optimization, Anweshana Vaizasatya

Dissertations

Coronary stents are slotted tubes made of metals, alloys, or polymers. They are deployed in human arteries, which are blocked by calcified plaque, to keep the arteries open and allow the blood to flow with ease. Coronary stents have been proven as an effective treatment device for heart diseases such as acute myocardial infarction. Design plays an important role for coronary stents to perform the clinical functions properly. Various parameters such as materials, structures, dimensions, and deployment methods etc., need to be considered in the design of coronary stents. There are numerous studies on design of coronary stents and many …

Booklet Of Selected Theses From The Ma In Criminology, Ma In Law, Ma In Child, Family And Community Studies, And The International Masters In Early Childhood Education, 2010-2012, Matt Bowden, Carmel Gallagher, Kevin Lalor

Dissertations

This booklet highlights and celebrates the research work of graduates from taught Masters programmes in the School of Social Sciences and Law:

• the MA in Criminology

• the MA in Law

• the MA in Child, Family and Community Studies

• the International Masters in Early Childhood Education, co-delivered with Oslo and Akershus University College of Applied Sciences (Norway) and the University of Malta (Malta).

The MA in Criminology and the MA in Law commenced in 2006 and the MA in Child, Family and Community Studies commenced in 2007. Each has quickly become established in its field as a …

Computer-Based Versus Paper-Pencil Modes Of Administration United States Government End Of Course Exams: Student Cumulative Grade Point Averages As Predictors Of Success, Barbara A. Ryan

Dissertations

Beginning with the No Child Left Behind federal legislation, states were required to use data to monitor and improve student achievement. For high schools, the Missouri Department of Elementary and Secondary Education chose End of Course Exams (EOC) to demonstrate levels of student achievement. The policy changed from school choice of paper-pencil or computer-based testing to mandated computer-based testing. This study examined whether this decision best demonstrates the level of student mastery. Using high school EOC test scores for United States Government exams as the independent variable and high school cumulative grade point average (CGPA) as the dependent variable, the …

The Relationship Between Parental And Adolescent Religiosity Factors And Adolescent Sexual Risk-Taking Among Older Adolescents In The Anglophone/Latin Caribbean, Karen Christoffel Flowers

Dissertations

Problem: Sexually active youth across the Anglophone/Latin Caribbean have been identified as among the most-at-risk for HIV infection. Studies conducted in the United States have identified parental and religiosity factors associated with adolescent sexual risk-taking, but these relationships remain largely unexplored in the Caribbean region.

Method: This cross-sectional study, based on survey data generated by the Seventh-day Adventist Caribbean Youth Survey, investigated the relationship between parental and adolescent religiosity factors and sexual at-risk behaviors reported by adolescents ages 16-18 years attending Seventh-day Adventist Church-operated secondary schools across the region. Pearson correlations and multiple regression analyses were used to assess the …