Digital Commons Network^™

A Holistic Computational Approach To Boosting The Performance Of Protein Search Engines, Majdi Ahmad Mosa Maabreh

Dissertations

Despite availability of several proteins search engines, due to the increasing amounts of MS/MS data and database sizes, more efficient data analysis and reduction methods are important. Improving accuracy and performance of protein identification is a main goal in the community of proteomic research. In this research, a holistic solution for improvement in search performance is developed.

Most current search engines apply the SEQUEST style of searching protein databases to define MS/MS spectra. SEQUEST involves three main phases: (i) Indexing the protein databases, (ii) Matching and Ranking the MS/MS spectra and (iii) Filtering the matches and reporting the final proteins. …

Diabetes Prevention Program: Exploring Spirituality And Spiritual Interventions On Outcomes, Sharon E. Plutko Long

Dissertations

Purpose

The purpose of this study is to explore a relationship between a modified Diabetes Prevention Program (DPP) for adults with pre-diabetes (pre-DM) or type-2 DM with variables of spirituality and religiosity (S/R) to illuminate the potential religion-health connection based in changes in participant weight, body mass index (BMI) and physical activity. A secondary purpose is identifying spiritual interventions used by faith-based DPP coaches in a group setting.

Methods

A mixed-methods study was conducted with 34 DPP participants and 11 DPP coaches who completed the core section (weeks 1-26) of DPP courses held in Macomb Country, Michigan. Independent variables are …

A Model For Propagating Educational Innovations In Higher Stem Education: A Grounded Theory Study Of Successfully Propagated Innovations, Raina Khatri

Dissertations

A critical problem in undergraduate science, technology, engineering, and mathematics (STEM) education is the slow uptake of innovative teaching strategies and materials. Developments from the STEM education research community can be shown to improve learning and retention outcomes, but the majority of new teaching strategies go unused by instructors. This problem is increasingly acknowledged by funding agencies such as the National Science Foundation, which now calls for “transferability and propagation” to be addressed throughout a project’s lifetime in the request for proposals. However, few publications synthesize what is known about propagating innovations into usable, actionable recommendations for developers in the …

Teaching Eye Contact And Responding To Name To Children With Autism Spectrum Disorder, Amelia M. Fonger

Dissertations

Eye contact and responding to name may be described as behavioral cusps because acquiring these skills extends contact with the environment, can allow behavior to come under the control of new contingencies, and may facilitate the acquisition of new behavior (Bloom & Lahey, 1978; Carbone, O’Brien, Sweeney-Kerwin, & Albert, 2013; Cook et al., 2017; Hanley, Heal, Tiger, & Ingvarsson, 2007; Rosales-Ruiz & Baer, 1997; Tiegerman & Primavera, 1984; Weiss & Zane, 2010). Eye contact and responding to name are commonly cited as targets for early intensive behavioral intervention; however, the existing literature is limited in its ability to guide a …

Elucidation Of The Toxicity Of Anthropogenic Nanoparticles In Environments Containing Heavy Metals, Chartanay Bonner

Dissertations

The design, synthesis, and applications of anthropogenic nanoparticles continue to rise as technologies utilizing the unique chemical and physical properties of materials with nanoscale dimensions emerge. Engineered silver nanoparticles (Ag NPs) possess antimicrobial properties toward several strains of antibiotic-resistant bacteria. The manufacturing and use of Ag NPs have led to their increased presence in the environment as pollutants. The interaction of Ag NPs with other pollutants influence their surface properties, aggregation state, stability and consequently, their toxic response toward microbial pathogens. In the present study, we examined the interaction of heavy metal ions (Cd²⁺, Hg²⁺, and …

Comparison Of Religious Problem-Solving Styles On The Use Of Problem-Focused And Maladaptive Emotion-Focused Coping Related To Financial Strain And Stress, Kirk A. Vander Molen

Dissertations

Poverty negatively impacts individuals and society as a whole in various ways, including emotional and physical health, relationships, education, crime, stress, and the economy (Adler & Ostrove, 1999; Anakwenze & Zuberi, 2013; Caplan & Schooler, 2007; Yoshikawa, Aber, & Beardslee, 2012). How people cope with the stress of poverty and engage with its causes and potential solutions impacts their capacity to survive, manage, and work toward improving their situation (Caplan & Schooler, 2007; Cohen & Wills, 1985; Santiago, Etter, Wadsworth, & Raviv, 2012). Problem-focused coping involves a person’s engagement to make plans, mobilize resources, and take action to manage or …

Biochemical And Biological Effects Of Irisin In A Model Of Diabetes Mellitus, Mohamed Omer Sirelkhatim Mahgoub

Dissertations

Diabetes mellitus (DM) is a highly prevalent health problem affecting more than 425 million people worldwide. It is associated with several detrimental complications such as neuropathy, nephropathy, retinopathy and cardiovascular diseases. Irisin is a novel hormone that plays a role in metabolism by stimulating the browning of white adipose tissue (WAT) into beige adipose tissue which acquires properties that are similar to those of brown adipose tissue (BAT). Several studies have attempted to characterize the roles of irisin in DM and obesity, however, contradictory results have been reported and physiological roles of irisin have been questioned by several researchers. In …

Sacrificial Dynamite: The Convergence Of Developed Empathy And Ongoing Relational Experience With God: A Grounded Theory, Toran Scott

Dissertations

This grounded theory study examined how participants described and reflected on their lives and what led them to choose sacrifice. The study was grounded in a Christian understanding of sacrifice, defined as the willful giving up of one’s positions or possessions for the sake of serving others. Using in-depth, open-ended interviews and follow-up interviews to co-construct meaning, participants were asked to reflect on their childhood, adolescence, and emerging adulthood to reflect on and describe any messages, relationships, or experiences that they thought contributed to their eventual choice to sacrifice. The interviews were free-flowing and filled with beautiful and engaging stories. …

Exploring The Learning Experience Of Higher Education Students In A Midwestern University Who Suffered Childhood Trauma, Dora Jean Washington

Dissertations

This study explored the learning experiences of higher education students who suffered childhood trauma (CT). Eleven participants both undergraduate and graduate who attended a Midwestern university self-identified as CT survivors. There was research on the negative impact of CT on learning in children and adolescents, as well as posttraumatic stress and veterans. However, the PI was unable to find research on the impact of CT on adults in higher education. Higher education institutions and professors may benefit from understanding how to help these students who often have an invisible learning disability. Research questions asked, what is the learning experience of …

Preparing Nursing Students To Respond To Disasters: Faculty Perspectives, Melissa Jayne Freshwater

Dissertations

This mixed methods study explored emergency preparedness and disaster response in the concept-based learning curriculum adopted by the Alabama Community College System (ACCS) in 2016. The concept-based curriculum employs active learning in lieu of the traditional lecture-style teaching methods.

This study addressed the problem that educators may be unfamiliar with this content and are unsure how to present this material to students. The purpose of this study was to gain insight on teaching methodologies, to better prepare nursing students on this content.

Kolb’s 1984 Experiential Learning Theory was the framework that parallels closely with this curriculum. Kolb emphasizes four stages …

Utilizing Parent Support Groups To Improve Parenting Efficacy And Relationships For Parents Of Inattentive, Hyperactive, Or Non-Compliant Children, Deborah Rickman Hake

Dissertations

School age children with ADHD suffer functional impairment in social development, show signs of emotional dysregulation, and have learning difficulties. Other psychological disorders may present, and some children may have one or more comorbid disorders. Studies demonstrated that the best practice was combined treatment. It was recommended that a pharmacological and behavioral approach be utilized. ADHD also affects the family. Parents of children with ADHD often neglect their own health caring and advocating for their child. The amount of parent involvement raising a child with ADHD can lead to reactive parenting, strained relationships with spouses, social and emotional isolation, depression, …

Teaching With Citizen Science: An Exploratory Study Of Teachers' Motivations & Perceptions, Georgia Bracey

Dissertations

With the continued emphasis in the United States on science teaching reform as a way to increase science learning and the scientific literacy of all, the integration of informal science learning activities like citizen science is emerging as a possible way to enhance formal science teaching and learning. There is a limited but growing number of studies indicating that the general public is learning science content and process from participating in citizen science, but research in this area is just beginning and the use of citizen science projects by teachers in formal classroom settings has barely been examined at all. …

Exploring The Moderating Effect Of A Caring Work Environment On The Relationship Between Workplace Mistreatment And Nurses' Ability To Provide Patient Care, Christine M. Moffa

Dissertations

Workplace mistreatment (bullying, horizontal violence, and incivility) has been shown to impact nurses' work satisfaction, job turnover, and physical and mental health. However, there are limited studies that examine its effect on patient outcomes. A correlational descriptive study of 79 acute care nurses was used to test a social justice model for examining the relationship between workplace mistreatment, quantified as threats to dimensions of nurses' well-being (health, personal security, reasoning, respect, attachment, and self-determination), and nurses' ability to provide quality patient care. In addition, this study considered the moderating effect of caring work environment among co-workers on nurses' ability to …

Female Athletic Directors In California: Attaining And Retaining The Position Of Athletic Director, Katherine Levensailor

Dissertations

Purpose: The purpose of this qualitative phenomenological inquiry study was to examine and describe how female athletic directors in California face and overcome barriers in attaining and retaining their positions.

Methodology: This was a qualitative phenomenological research study, incorporating an interview research design. The participants in this study were current female athletic directors within in the Southern and San Diego Sections of the California Interscholastic Federation (CIF). The researcher conducted 15 semistructured interviews and collected artifacts that were coded for themes to develop a conceptual framework with which to understand the phenomena that females experience in attaining and retaining their …

Thermodynamics In Large Hairpin Polyamide-Dna Interactions, Yang Song

Dissertations

Human papillomavirus (HPV) is a common sexually transmitted virus responsible for cervical cancers, and its infection is currently incurable. Only a few vaccines against high-risk HPV strains are available. Hairpin polyamides (PAs) in different sizes (8-20 units long) bind DNA in different lengths. They have been shown to have different anti-HPV activities in cell culture.

The interaction between PA and DNA is stabilized by two types of molecular forces: attractive and repulsive forces. Attractive forces include hydrogen bonds, van der Waals contacts and electrostatic forces between PA and DNA. Repulsive forces include the hydrophobic effect, which forces the PA out …

Feeling Valued, Supported, And Satisfied: Perceptions Of Special Educators And Principals, Tanya Lynn Rapert

Dissertations

High teacher attrition and low teacher retention rates continue to plague the field of special education, which leads to teacher shortages year after year (Andrews & Brown, 2015; Vittek, 2015). Solutions for increasing special education teacher retention continue to be explored (Billingsley, 2005; Brownell & Sindelar, 2016; Tyler & Brunner, 2014). The purpose of this study was to discover trends or themes connecting special education teacher work conditions and job satisfaction, principal support, and decisions of teachers to continue teaching special education. Participants for this study were special education teachers and principals from 60 accredited public K-12 school districts in …

Examination Of The Educational Impact Of Delayed Identification Of Gifted Students, Timothy Perkins

Dissertations

Gifted programming provides many children with an opportunity to reach their potential (Olszewski-Kubilius & Thomson, 2015). For years, gifted studies have been underfunded (Azano, Callahan, Missett, & Brunner, 2014). A lack of research into gifted programming has left glaring holes in the current understanding of best practices (Plucker & Callahan, 2014). This study included an examination of gifted programming from the standpoint of cognitive theory. The researcher examined archival data from School District A to determine students’ overall academic success when compared to the number of years spent in gifted programming. The data yielded a negative correlation between years spent …

Haemosporidian Parasites And Host Immune Function Of Galapagos Avifauna, Maricruz Jaramillo

Dissertations

The large number of emergent infectious diseases witnessed in the past few decades has increased interest in the ecology and distribution of potentially threatening pathogens worldwide. Island species are often considered more vulnerable to parasites due to their impoverished parasite communities, long isolation from disease and low genetic diversity. Avian surveys done by our group on the Galapagos Islands have found various pathogens infecting their endemic avifauna, including haemosporidian parasites of the genera Plasmodium and Haemoproteus. My research seeks to understand the relationships between two haemosporidian parasites (blood parasites) and their multiple bird hosts in Galapagos and to explore …

Discovering The Best Practices For Design And Development Of High School Online Physical Education: A Phenomenological Study, Marie Crosby

Dissertations

Purpose: Online physical education (OLPE) is a burgeoning field with questions and disadvantages that need to be addressed for its continued growth. With out-of-date guidelines and best practice not established for OLPE, curricula are being designed and developed without consistency. Current standards are needed to assess the design of OLPE to ensure that courses meet state and/or national standards, and quality guidelines in the online environment. The purpose of this qualitative study was to identify and describe the best practices used in the design and development of high school OLPE curricula based on the International Association for K-12 Online Learning …

Juvenile Programming Activities In Detention Facilities: Self-Adjustment And Levels Of Stress, Stephen Davis

Dissertations

The significance of this study was to examine if adolescents in a juvenile detention center in St. Louis City could self-adjust, cope, or adapt to their levels of stress. There was a great deal of literature available supporting the notion of utilizing affective tactics in combating stress levels among various age groups. However, there was very little information provided on at-risk adolescents in a juvenile detention center confronted with dangerous levels of stress. The importance of understanding how these detained adolescents, between the ages of 12 and 17, approached dealing with their stress was not just beneficial to them, but …

Genomic And Cellular Studies Establish The Pathogenesis And Cellular Mechanisms Of Disease-Causing Mutations In Families With Autosomal Recessive Disorders, Nesreen Khalid Ahmad Al Jezawi

Dissertations

The majority of the reported genetic disorders in the UAE population are of the autosomal recessive type, which is mainly due to high rates of consanguinity within the UAE national population, and within a significant proportion of other UAE expatriate communities; such as Arabs and Pakistanis. It is estimated that more than 50% of all marriages among Emiratis occur between biologically related couples, with first cousin marriages being the highest. That could be attributed to sociocultural values in the region. Successful management of genetic diseases can be achieved by the implementation of effective preventative programs that could help reduce the …

Visualization Of Co-Authorshipin Dit Arrow, Dan Xu

Dissertations

With the popularization of information technology and the unprecedented development of online reading, the management and service of the library are facing severe challenges; the traditional library operation mode has been challenging to optimize the service. At the same time, there is also a fatal impact on library collection and systematic management, however, with the development of visualization techniques in management and service, the library can alleviate the effect of the current network information basically, which achieves the intellectual development of library field. This study empirically provides the evidence to indicate that the force directed layout has the statistically significant …

Spoilage Detection In Raspberry Fruit Based On Spectral Imaging Using Convolutional Neural Networks, Karthik Kuchangi Jothi Prakash

Dissertations

Effective spoilage detection of perishable food items like fruits and vegetables is essential for retailers who stock and sell large quantities of these items. This research is aimed at developing a non-destructive, rapid and accurate method which is based on Spectral Imaging (SI) used in tandem with Convolutional Neural Network (CNN) to predict whether the fruit is fresh or rotten. The study also aims to determine the number of days before which the fruit rots. This research employs a primary, quantitative and inductive methods to investigate the Deep Learning based approach to detect fruit spoilage. Raspberry fruit in particular has …

The Impact Of Family Satisfaction, Racial Identity And Perceived Ethnic Discrimination On African-American College Students' Vulnerability To Stereotype Threat, Erica Lynn Featherson

Dissertations

Problem

Stereotype threat is something that has plagued the African-American community for decades. However, there is no direct research on the protective factors that could mitigate or exacerbate the effects of stereotype threat on African-Americans. The present study is intended to focus on the relationship between family satisfaction, racial identity, perceived ethnic discrimination and African-American college students’ vulnerability to stereotype threat.

Method

This study used the Family Satisfaction Scale (FSS), The Black Racial Identity Attitude Scale (BRIAS), The Perceived Ethnic Discrimination Questionnaire (PEDQ) and the Stereotype Confirmation Concern Scale (SCCS) to explore the relationships between the four variables. A structural …

The Influence Of Social Support And Basic Psychological Needs Satisfaction On Student Academic Motivation At A Cameroonian University: Structural Equation Modeling, Samuel Adamou

Dissertations

Problem

The growing number of students at the university level in Cameroon created maladaptive behaviors including lack of behavior adaptation, interests, respect, happiness, self-esteem, which led to strikes, vandalism, academic failure and resulting in school dropout (Nwaimah, 2008). The Cameroonian government proposed a number of reforms to solve these issues. One of the major proposed reforms consisted of implementing the Bologna Model in higher education through borrowing and transferring of policies, ideas, and practices from a European higher education area (Eta, 2015; Mngo, 2011). Yet despite the surface progress, the question of how to enhance student learning and improve instruction …

Use Of Stories In Courses And Student Engagement At Southwestern Michigan College, Heather Day

Dissertations

The purpose of this study was to examine the nature of the relationship between the use of narrative in the classroom and student engagement. In this regard, the strategies used to connect students to learning experiences are important to ensuring their engagement. Research questions addressed: 1) What is the level of academic engagement among students at Southwestern Michigan College? 2) To what extent are stories embedded into academic courses? 3) To what extent is student engagement related to the use of stories in students’ courses?

To address these research questions, the researcher used two surveys. Survey one used secondary data …

The Role Of Multiple Dimensions Of Organized Activity Participation, Impulsivity, And Parental Monitoring On Externalizing Behavior Among Low-Income, Urban Adolescents., Amy Governale

Dissertations

Because the majority of teenage deaths are not due to illness, but instead attributed to risk behaviors, it is pertinent to determine under what circumstances adolescents are likely to injure themselves or others. One well-studied protective factor of adolescent externalizing behaviors is participation in organized activities. Unfortunately, the majority of research involving adolescents’ engagement in organized activities examines single dimensions of participation (intensity, duration, and breadth) at a time, within samples of middle-class, Caucasian youth. Few studies have examined how multiple dimensions of participation in organized activities, including how uninterrupted engagement in organized activities from school year to summer months, …

Gender Beliefs Of Teachers In Orthodox Jewish Early Childhood Programs, Ilana Chai Dvorin Friedman

Dissertations

The goal of this study was to explore gender beliefs of teachers in Orthodox Jewish coeducational early childhood programs and give voice to their experiences and viewpoints. Concurrently, a feminist poststructural and queer theory lens was utilized to uphold Gorsetman and Sztokman’s (2013) claim that Orthodox Jewish schooling is fraught with messages and discourses that inhibit “educating for the divine image” (p. 30). This study maintained the need to examine gender consciousness within Orthodox Jewish schooling to promote inclusion and equality.

As young children actively engage in gender construction, teachers play a vital role reinforcing and/or challenging norms and available …

Best Practices In Global Mental Health: An Exploratory Study Of Recommendations For Psychologists, Kimberly Hook

Dissertations

This qualitative study aimed to provide best practice recommendations for psychologists who work within the field of global mental health. Global mental health seeks to improve mental health treatment equity on a worldwide scale, through mechanisms such as task shifting, advocacy on a governmental/community/systems level, and through capacity building. Global mental health is a growing field, and there have been calls for increased engagement in these efforts from the psychological community. Nevertheless, few recommendations are in place regarding how to practically move towards these goals in an ethical, culturally-relevant manner, though other related disciplines, such as psychiatry and public health, …

Biophysical Studies Of Guanine Nucleotide-Binding Alpha Subunits, Brian Leverson

Dissertations

Guanine nucleotide-binding (G?) proteins have been intensely studied over the years due to their role as signal transduction proteins. Proper function depends on three flexible switch regions that are involved in the relatively slow hydrolysis of GTP, allowing for the proteins to act as a molecular on/off switch. The structure of a protein is essential to its biological function. Occurrences of mutations in the genes GNAS and GNAI1 to highly conserved arginine residue in the switch II region have been detected in several types of cancers.

Utilizing the combinations of temperature denaturation, kinetics assays, and molecular dynamics, we plan to …