Digital Commons Network^™

Implementation Of Operational Excellence: Challenges Related To Employee Perception And Organizational Culture, Ruben Fontes

Dissertations

Industries that are traditionally technical and hierarchical present a variety of challenges for today’s leaders, particularly given the rapidly evolving, technology-driven global business environment. In addition, the movement toward more collaborative and horizontal work environments encourages a uniquely collective perspective comprised of individuals who are expected to continually shift between innovation and conformance. Success in the contemporary business environment largely depends on a firm’s speed and efficiency in relation to its competitors, which challenges leaders to not only remain on the cutting edge of their respective industries, but also stay “in tune” with the inner workings of their organizations in …

The Role Of Foxo Transcription Factors In Alcohol-Induced Deficient Fracture Repair, Philip M. Roper

Dissertations

Proper and complete repair of a bone fracture is essential in quality of life maintenance, but poor healing and fracture malunion are still medically and socially relevant problems. Alcohol abuse impairs normal fracture healing, leading to delayed or incomplete union. This dissertation aims to clarify mechanisms behind this alcohol-induced impaired healing, thereby elucidating potential methods of intervention.

Alcohol-induced oxidative stress has been linked to many morbidities associated with alcohol abuse. This dissertation elucidates a potential mechanism through which alcohol inhibits fracture healing by increasing oxidative stress. Using a rodent model, I found that alcohol exposure decreases fracture callus formation and …

Saving Marriage One Relationship At A Time: Culture, Family, And Social Change In Christian Premarital Counseling, Courtney Ann Irby

Dissertations

Despite concerns about the decline of marriage in the United States, research has consistently revealed that getting married and staying married remain important to Americans. The value attached to marriage, however, is coupled with an ethic of individualism that results in a focus on personal satisfaction and fulfillment in marriage. While this individualized marriage has been established at both the macro level as part of an American marriage culture and at the micro level in the preferences and actions of individuals, less attention has focused on how communities mediate, respond, and react to these beliefs. I draw from a comparative …

Men As Caregivers: Latino Fathering Of Children With Cancer, Noe Mojica

Dissertations

Although women are often viewed as primary caregivers of children, the twenty-first century social conditions are challenging men in the Latino community to assume an increasingly active role in raising children. This study explored the relationships between Latino fathers' masculine identity, caregiving and coping when faced with the demands generated by having a child diagnosed with cancer. The study pursued to inquire the relationship between Latino fathers’ masculinity, their caregiving activities, and how they cope with pediatric illness. Results indicated no significant relationship between masculinity and caregiving or coping. However, there was a significant relationship with conflict between work and …

Neural Correlates Of Political Attitudes: Emotion And Ideology In The Brain, Dane Gorman Wendell

Dissertations

Do conservatives and liberals have differing sensitivities to avoidance, inhibition, and negative emotion? Do psychological factors beneath our conscious awareness underlie the political ideologies we embrace? Political science researchers have broken new ground over the past ten years in our understanding of the psychology and physiology of political ideology. However, large questions remain about how political ideology may be related to avoidance motivations and negative emotion. This work expands our current knowledge in this area by presenting three studies with multiple methodologies: original survey data, electroencephalographic measurements, and behavioral experiments in a lab setting. Working in the tradition of J.A. …

Efficient Lossless Compression Of Regions Of Interest In Hyperspectral Imagery, Hongda Shen

Dissertations

This dissertation addresses the problem of efficient lossless compression of regions of interest (ROIs) in hyperspectral images. To this end, a novel framework for evaluating the performance of predictive lossless compression schemes on ROIs without no-data regions was introduced. Furthermore, mixture geometric distributions were used to model the residual data from the predictors along with an information-theoretic analysis of the compression performance. Then, three practical predictive lossless compression methods were introduced, including a modified least mean square filtering method, a least mean square filtering method based on the maximum correntropy criteria, and a two-stage predictor using context similarity weighted averaging …

Characterization Of Ubiquitin-Proteasome Dynamics In Caenorhabditis Elegans Muscle Cells During Protein-Folding Stress, Gregory A. Skibinski

Dissertations

In order to adapt to changing conditions and life stages, cells must remodel the composition of the proteome by specifically removing obsolete or damaged proteins. Failure to remove proteins at the appropriate time can cause a variety of cellular dysfunctions that can lead to cell death and conditions such as cancer, Huntington's, Parkinson's and Alzheimer's disease. Protein quality control is especially important during aging and stress, as the accumulating load of damaged, misfolded, and aggregated proteins can overwhelm the cell's ability to maintain the proteome. The ubiquitin-proteasome system is responsible for the specific degradation of many proteins within eukaryotic cells. …

Capacity Building For International Development Practitioners Through An Off-Campus Graduate Education Program, Ralph Charles Wood

Dissertations

Problem

Andrews University offers a graduate off-campus program in international development, the Master of International Development Administration (MIDA). The stimulus for this study came from the fact that there had never been an extensive investigation of the capacity building impact on the graduates of the off-campus Master of International Development Administration of Andrews University. Coupled with this, there was a very limited body of research on the importance and effect of education in international development when it comes to building the capacity of the practitioners of international development. This study determined the alumni’s perceptions of experiencing individual capacity building and …

Exploring The Transition Experience For The First Time Local Conference Presidents In The North American Division Of Seventh-Day Adventists: Narratives From Conference Presidents' Career Transitions, David E. Weigley

Dissertations

The position of the president of a conference in the North American Division of Seventh-day Adventists (a senior leadership role) has currently no policy stipulating leadership training prerequisites. Leaders transitioning into the president’s position typically are selected from a pool of successful pastors, departmental directors, and executive secretaries by a constituency meeting of delegates from local churches and conference institutions.

This qualitative study probed the transition of 12 first-time local conference presidents. The information was gathered by recording in-depth interviews. Eight themes surfaced from the exploration. Leaders experienced the transition as overwhelming, challenging their spirituality, involving new constellations of relationships, …

Musical Listening Interest, Socio-Demographic And Socio-Psychological Factors As Predictors Of Test Anxiety Among Students Of A Christian University In Jamaica, Wayne E. N. Ireland-Cleghorne

Dissertations

Problem

There is an enormous deficit in the literature on the factors associated with test anxiety generally, and test anxiety and music listening interest in particular, in the Caribbean region. This deficit is made even more distinct by the numerous studies that exist on test anxiety elsewhere and the effect it has on students’ behavior and performance in the classroom.

Purpose

The purpose of this study was to examine the relationship between musical listening interest and test anxiety, while controlling for variables that are deemed plausible predictors of test anxiety. Predictor variables utilized include sociodemographic factors such as gender, age, …

Faculty And Staff Perceptions Of Stress, Efficacy, Personality, And Health Practices During Implementation Of Comprehensive Educational Change At One Secondary School, Virginia Mae Lonser

Dissertations

Problem

Private faith-based schools have experienced a severe drop in enrollment over the past few years contributing to perceptions of job insecurity. Especially in the realm of residential secondary education has this observation been true. This descriptive case study investigated perceptions of stress of secondary-school faculty and staff involved with a school-based systemic change implementation in an attempt to turn around the attenuation in enrollment.

Method

This research study followed a bounded mixed-methods case design using data collected as participant observations of the 24 residential secondary-school faculty and staff and tests were performed to show relationships between variables. Tools were …

The Bonds That Break: Sibling Abuse Perpetration Behaviors As Correlates Of Peer Bullying Perpetration Behaviors: A Structural Equation Model, Curt Bachman

Dissertations

Problem

The literature suggests that the perpetration of sibling violence and peer bullying behaviors present multifaceted concerns for both families and society. Furthermore, there are differences in how the perpetration of peer bullying and sibling violence behaviors have been emphasized in the United States. However, research examining how these experiences may be related is limited.

Method

A survey was used to collect data on lifetime reports of sibling abuse and peer bullying perpetration behaviors from a sample of 252 adults. A total of six variables were measured using an altered version of the Conflict Tactics Scale.

Results

Using partial least …

The Impact Of Values Clarification And Expression Of Beliefs On Dysfunctional Leadership Among Church Lay Leaders, John F. Cosgrove

Dissertations

Problem

Leaders face challenges from within themselves and from others. Dysfunctions within the leader and with their group can lessen leadership effectiveness. It appears some leaders manage these dysfunctions better than others. More needs to be understood about how these dysfunctions are best mediated and some have suggested clarification of values and beliefs can do that.

Method

This study followed a quantitative correlational research design. Data were obtained using surveys that 84 participants completed on line. Participants were selected from current lay leaders and former lay leaders of not more than three years past from Christ United Methodist Church of …

A Theology Of Missional Leadership In The Book Of Revelation, Gyeongchun Choi

Dissertations

Problem

Leadership styles and the attendant behavior of mission practitioners and church administrators too often demonstrate leadership attitudes and practices that reflect cultural norms while violating biblical norms. There is both historical and contemporary evidence of a predictable migration from leadership as service to leadership as control—such as autocracy, coercion, self-ascendancy, and dominance. These problems are found in leadership practices primarily informed by cultural norms apart from God’s Word. These norms vary widely and may even be practiced within the faith community thus violating biblical principles. This reality creates an urgent need for the application of biblical principles that transcend …

Observation And Coaching As A Professional Learning Model To Support The Implementation Of Co-Teaching, Mary Alice Henley

Dissertations

Purpose

This qualitative study provides a description of a professional learning model using observation and coaching for teachers who participated in training regarding co-teaching to support the implementation of co-teaching.

Method

The study involved participants who were general and special educators from grades K-12 across urban, rural, and suburban school districts in Connecticut. The study included 329 observations of 136 co-teaching teams from 44 schools in 14 districts over the course of 14 years. Classroom observations of 15-20 minutes were initiated in schools with co-teachers in their natural settings using an open-ended observation protocol recorded on the Connecticut Co-Teaching Technical …

The Effects Of Learning About Black History On Racial Identity, Self-Efficacy, Self-Esteem, And Depression Among Low-Income African American Male Youth, Quentin L. Stubbins

Dissertations

Problem

The literature is clear that African American youth receive a shallow account from parents and schools about Black history. More importantly, African American male youth from low-income families rarely receive information about Black history. Youth today watch television for entertainment and through watching television learn about new facts and information. African American youth watch more television than any other ethnic group. The media has a long history of portraying African Americans in a negative light. The negative media portrayals of African Americans have impacted their racial identity, self-esteem, self-efficacy and their mental health. No research has been done on …

Special Education Disproportionality Through A Social Lens: A Mixed Methods Approach, Marianne J. Fidishin

Dissertations

The disproportionate nature of special education, notably with African American students, is longstanding and most pronounced in judgmental eligibility categories such as intellectual disability and emotional disturbance. Numerous studies on disproportionality conclude there is not a single causative factor, but point to the multifactorial nature of the issue and the complex interplay among different factors. Research related to the role social factors exhibited in an institution have on special education referral and eligibility determination is more limited. This is important since practices employed during the eligibility process take place within the institution’s social environment and are underpinned by the beliefs …

Mechanism By Which Commensal Bacteria Limit Inflammation, Mallory Paynich

Dissertations

Trillions of bacteria live within the gastrointestinal tract and are critical for maintaining intestinal homeostasis; however, the mechanisms utilized by specific bacterial molecules to contribute to homeostasis are not well understood. We utilize a mouse model in which a single oral dose of the probiotic, Bacillus subtilis, protects mice from acute colitis induced by the enteric pathogen Citrobacter rodentium. Our goal is to elucidate the mechanism by which B. subtilis prevents inflammation.

We identified exopolysaccharides (EPS) to be the active molecule of B. subtilis, and a single dose of EPS protects mice from disease. EPS binds F4/80+CD11b+ peritoneal macrophages, and …

Keeping Schools Catholic: Discipleship As Paradigm For Administrators, Teachers, Staff And Students, James (Deporres) Charles Durham

Dissertations

Of the many accomplishments of the Catholic Church in the United States, one of the most known is the Catholic School System. In 1965, over 4.4 million children were educated in the 10,667 Catholic elementary schools, and almost 700,000 in the 1,527 Catholic high schools (Center for Applied Research for the Apostolate, 2013). The mission of the school was embodied, literally, in these skilled male and female religious who taught in these schools. But the number of male and female religious was not sustained, leading to the question of how the religious mission of the school will continue. The number …

Adenovirus Evasion Of Cell-Intrinsic Immunity, Andrew Michael Burrage

Dissertations

Virus cell entry represents one of the earliest opportunities for a host to respond to infection. Understanding the processes of pathogen detection and restriction employed by the host, as well as strategies utilized by the virus itself to evade such processes, is critical in developing therapeutics to counter pathogenesis. Adenovirus (Ad) infections are self-limiting in healthy populations, but can be devastating to individuals with compromised immune systems. Currently, no specific antiviral treatments exist to combat Ad infections in susceptible populations. However, because Ad infections are not severe in healthy individuals, employing replication-defective Ads as vaccine vectors is generally regarded as …

United States Foreign Policy Toward Hiv/Aids In Africa: The Role Of Pharmaceutical Companies In The Formulation And Implementation Of The President’S Emergency Plan For Aids Relief (Pepfar) 2003-2008, Toussaint Kafarhire Murhula

Dissertations

During his 2003 State of the Union Address, President Bush announced his Emergency Plan for AIDS Relief (PEPFAR) and asked Congress, over the next five years, to authorize the appropriation of $15 billion to provide treatment, prevention and care to people infected and affected by HIV/AIDS, mostly in Sub-Saharan Africa. Given the existing pattern of neglect and indifference in U.S.-Africa relations and the Bush campaign’s statement in 2000 dismissing Africa from his foreign policy priorities, what then justifies his administration’s undertaking of this massive foreign policy change?

My dissertation offers insight into the role played by private US pharmaceutical companies …

Emature: Intergenerational Networks In Digital Media Spaces, Andras Lukacs

Dissertations

While the literature on adolescent usage of the Internet and mobile communication technology is burgeoning, the technological affordance of increased intergenerational contacts and intergenerational friendships received less attention. This project documents how intergenerational virtual networks operate in one particular massively multiplayer online game (World of Warcraft) from the standpoint of adolescent players. Online social worlds are similar to offline settings in a lot of ways. Users must obey certain behavioral standards and follow established rules and moral codes to participate. Despite accounts of online democracy and networked individualism, control and authority is central to the functioning of these environments. Power-relationships …

Expectations And Quality Of Life During The Antepartum And Postpartum Period, Mary Kathryn Adams

Dissertations

During pregnancy, women frequently anticipate birth and motherhood with unrealistic images and expectations which are formed by personal experience and society’s portrayal of motherhood (e.g., books and movies). How these expectations impact the postpartum period for women has not been well studied. However, research has identified a link between maternal expectations, reality, and negative emotional responses. When expectations are met, the experience of motherhood may be a positive one. However, when these expectations are not met, the potential for negative emotional responses may be greater. The postpartum period is a significant period of adjustment, and depression occurs in about 13%–19% …

Cardiac Calcium Atpase Dimerization Measured By Fluorescence Resonance Energy Transfer And Chemical Cross-Linking, Daniel Blackwell

Dissertations

The cardiac sarco/endoplasmic reticulum calcium ATPase (SERCA) establishes the intracellular calcium gradient across the sarcoplasmic reticulum membrane. It has been proposed that SERCA forms homo-oligomers that increase the catalytic rate of calcium transport. We investigated SERCA oligomerization in rabbit left ventricular myocytes using a photoactivatable cross-linker. Western blotting of cross-linked SERCA revealed higher molecular weight species consistent with SERCA oligomerization. Fluorescence resonance energy transfer (FRET) measurements in cells transiently transfected with fluorescently-labeled SERCA2a revealed that SERCA readily forms homo-dimers. These dimers formed in the absence or presence of the SERCA regulatory partner, phospholamban (PLB) and were unaltered by PLB phosphorylation …

Kant, The Natural Law, And The Question Of Normativity In Catholic Ethics, John Robert Crowley-Buck

Dissertations

This dissertation explores the question of normativity in 21st century Catholic ethical reflection. While, today, the natural law tradition frames and founds the normative question in Catholic ethics in terms of the imago Dei, this project explores the moral philosophy of Immanuel Kant and the challenge it presents to the natural law's claim to normativity. Specifically, this dissertation argues that in Kant's ethics, the normative question is answered in terms of the dignity of humanity, rather than the imago Dei, and that the dignity of humanity is a more relevant, shareable, and normative grounding for ethical reflection. To this end, …

Dating Violence Prevention Through A Change In Gender Norms, Katie Doud

Dissertations

Gender norms that promote male dominance and control lead to greater violence against females and deleterious health effects for males (Reed, Raj, Miller & Silverman, 2010). A strict adherence to female gender roles is associated with a greater likelihood to be in an abusive relationship and a greater length of time to leave an abusive relationship (Molidar & Tollman, 1998). Adolescence is a developmental time where boys and girls rigidly follow gender stereotypes (Alfieri, Ruble, & Higgins, 1996). Three-fourths of adolescents have been in a dating relationship by their senior year in high school (Carver et al., 2003). The combination …

Evaluating The Impact Of Integrative Mental Health Treatment In Veterans With Post-Traumatic Stress Disorder, Bella Etingen

Dissertations

High numbers of US Veterans experience post-traumatic stress disorder (PTSD), but, many do not subsequently seek mental healthcare. Integrated mental health (IMH) models of treatment bring mental health professionals into the primary care setting, allowing Veterans to receive comprehensive treatment during primary care visits. The IMH treatment model may bridge the gap for Veterans with PTSD who need care and those who actually receive it. This study examined the impact that IMH has on Veterans with PTSD receiving care from VA. Using several methods of data collection (medical chart reviews, VA administrative databases, a mailed survey of patient perception of …

Social Skills In Youth With Spina Bifida: A Longitudinal Multimethod Investigation Of Bio-Neuropsychosocial Predictors, Christina Ehrman Holbein

Dissertations

Objective: Despite research documenting social dysfunction in youth with spina bifida (SB), little is known about the etiology of these social difficulties; most investigations identifying predictors of social deficits have concentrated exclusively on one domain. This longitudinal study examines the relative predictive power of neurocognitive (attention and executive function), family (cohesion and conflict), and health-related (body mass index, condition severity) variables on later social skills in youth with SB.

Methods: 112 youth with SB (T1 mean age = 11.19 years) and their families participated in study visits two years apart. Study variables were assessed by multiple methods (questionnaire, medical chart …

Development Of Folate Directed, Protein Based Photodynamic Therapy Agents, Rojenia Jones

Dissertations

To attack cancer cells in a specific manner, we have developed a folate-targeted, photodynamic therapy (PDT) agent. The folate (FA) and the chlorin e6 (Ce6) photosensitizer were attached to bovine serum albumin (BSA) using carbodiimide chemistry. Since over 50% of cancers overexpress folate receptors, FA-BSA-Ce6 can be taken up by them and is an effective PDT agent. Hela cells exposed to FA-BSA-Ce6 in the dark showed no cytotoxicity. Upon exposure to light, the conjugate was dose (time and concentration) dependent. Concentrations less than or equal to 2 µM were not effective at killing Hela cells but concentrations of at 5 …

Moral Distress And The Health Care Organization, Andy Kondrat

Dissertations

A health care professional may experience moral distress when she believes she knows the ethical course of action in a given situation, but is unable to enact that plan, or must do otherwise. This dissertation argues that health care organizations have an ethical obligation to address moral distress in their health care professionals, and that common responses to moral distress are ethically insufficient due to their reliance on hierarchical solutions when hierarchies are, in fact, often a cause of moral distress. Thus, health care organizations, as moral agents, have a responsibility to find a non-hierarchical response to moral distress.

In …