Digital Commons Network^™

Cultivating Compassion In Undergraduate College Students: Rhetoric Or Reality?, Michael Lovette-Colyer Phd

Dissertations

While American colleges and universities are unparalleled in their ability to produce disciplinary-based knowledge through research and scholarship, their ability to encourage students to use the information and methods about which they are learning to create positive social change has lagged. Aware of the magnitude of today's global issues and dissatisfied with the current disparity between the world's reality and university curricula, scholars have begun to re-imagine the role of higher education in forming the leaders who will face our most pressing problems. Founded to provide education integrated with the formation of values, a significant number of Catholic colleges and …

Exercise Alters Glial Cell Line-Derived Neurotrophic Factor (Gdnf) Protein Content In The Spinal Cord, Monica Janine Mccullough

Dissertations

Neurotrophic factors may play a role in exercise-induced neuroprotective effects; however, it is not known if exercise mediates changes in glial cell line-derived neurotrophic factor (GDNF) protein levels in the spinal cord. The aim of the studies described herein was to determine if exercise alters GDNF protein expression in the lumbar spinal cord of healthy and diseased animals. The lumbar spinal cord was analyzed from adult rats aged 6-, 12-, 18- and 24-months, and from transgenic amyotrophic lateral sclerosis (ALS) mice and wild-type mice aged 3 months. Animals had undergone either forced wheel running, voluntary wheel running or swimming for …

Evaluation Of A Successful High Risk Nursing Student Assistance Program: One Adn Program's Journey, Ciaran O'Sullivan

Dissertations

A college education is, for many in America, part and parcel of the American Dream, and is certainly achievable. For countless reasons, students may enroll at community colleges underprepared, unprepared, anxious, and destined for a high risk of failure. Although community colleges are higher education institutions open and accessible to all who want to pursue an education, some degree programs are selective enrollment programs, such as nursing. Considering the stringent admission criteria and rigors of an associate degree in nursing (ADN) program, few are admitted. However, due to the pending shortage of registered nurses, assistance programs to help high risk …

Using Behavior-Analytic Techniques To Benefit An African Non-Governmental Organization: Improving And Expanding Services, Amy L. Durgin

Dissertations

The combination of a slowly recovering global economy, increased corporate competition, and higher standards from donors with respect to governance and accountably have posed significant challenges for nonprofit organizations around the world. In order to survive, these organizations must adapt their operational models and find new strategies for delivering on strategic goals, improving operational efficiency, and differentiating their services. The purpose of the present project was to employ behavioral techniques to improve operational efficiency and to develop opportunities for organizational growth by expanding the range of services provided by a nongovernmental organization (NGO) in East Africa that uses scent-detection rats …

Artificial Immune Systems And Particle Swarm Optimization For Solutions To The General Adversarial Agents Problem, Jeremy Mange

Dissertations

The general adversarial agents problem is an abstract problem description touching on the fields of Artificial Intelligence, machine learning, decision theory, and game theory. The goal of the problem is, given one or more mobile agents, each identified as either “friendly" or “enemy", along with a specified environment state, to choose an action or series of actions from all possible valid choices for the next “timestep" or series thereof, in order to lead toward a specified outcome or set of outcomes. This dissertation explores approaches to this problem utilizing Artificial Immune Systems, Particle Swarm Optimization, and hybrid approaches, along with …

The Relationship Of Academic Courses To Skills Required Of Automobile Repair Technicians, Stephen H. Freund

Dissertations

The primary objective was to show the important need of academic skills, specifically general education coursework, to the effectiveness of the technician’s expertise in the field of automobile repair. Additionally, I emphasized that one of the keys to the quality of the technician’s education is the method of instruction analyzed through Henschke’s Five Building Blocks. I communicated with 35 diversely selected and cooperative employers located in the Midwestern section of the United States. I obtained this arbitrary selection from the Yellow Pages of this region. I conducted personal visits to their locations at which time I informed them of the …

Development Of Luminescent Probes For Ultrasensitive Detection Of Biopolymers, Their Complexes, And Living Cells, Laura A. Wirpsza

Dissertations

New luminescent probes with enhanced brightness convenient for bioconjugation were synthesized and tested in major biological applications including the detection of nucleic acids and living cells. The first project used luminescent lanthanide ion probes that take advantage of hyper-sensitive acquisition of their long-lived emission signal in time- resolved mode, which avoids short-lived background fluorescence of the medium. Two model carbostyril fluorophores (cs 124-CH₃ and cs 124-CF₃) were modified by inclusion of two spacers (diamino and bi-phenyl) for the attachment of amine and thiol reactive cross-linking groups. In this project, time-resolved measurements are presented for spectroscopy and microscopy. …

Fabrication And Evaluation Of A Collagen-Based Fiber-Gel Three-Dimensional Construct For Peripheral Nerve Repair, Mevan Lakmal Siriwardane

Dissertations

Nerve regeneration following a peripheral nerve injury often relies on growth cone- mediated guidance and the presence of Schwann cells to support the regenerating axons and remyelinate portions of denervated nerve pathways. The emphasis of this work is to develop a synthetic nervous tissue construct that contains similar basal lamina or extracellular matrix to peripheral nerve in order to achieve a level of effectiveness in nerve repair and future peripheral nerve regeneration applications. To this end, three- dimensional nervous tissue constructs consisting of type I collagen are fabricated into a composite biomaterial scaffold to promote contact-guided growth of neuronal and …

Astrocytes Modulate Microglial Phenotype And Dendritic Cell-Like Properties, Nischal K. Padala

Dissertations

Microglia are the resident immune cells of the CNS. In the healthy CNS, they express negligible levels of MHC II molecules as well as co-stimulatory molecules CD40, CD80 and CD86 necessary for antigen presentation to and activation of T cells. Co-stimulatory molecule expression can be induced in isolated microglia in vitro by sequential treatment with granulocyte monocyte colony-stimulating factor (GM-CSF) followed by lipopolysaccharide (LPS). Upon such treatment, they become mature dendritic cells (DCs), capable of activating T cells. However, microglia are not isolated in life, but rather exist in an environment enriched by other cells, notably astrocytes.

Therefore, to determine …

Handel's Maser-Soliton Theory Of Ball Lightning: The Creation Of Stable Three-Dimensional Cavitons By An Atmospheric Maser Within An Open Resonator, Glenn Andrew Carlson

Dissertations

This dissertation develops details of Handel’s Maser-Soliton Theory of ball lightning. The atmosphere between a thundercloud and the Earth’s surface is modeled as an idealized stable open resonator with water vapor as the active medium and the thundercloud and Earth’s surface as reflecting surfaces. The stable resonator generates a maser beam that narrows to the beam waist at the Earth’s surface, which is assumed to be planar. Two candidate rotational transitions are identified within the v1v2v3 = 010 vibrational band of water having wavelengths of 13.9 cm and 1.12 cm, and relevant spectroscopic parameters are retrieved from the HITRAN 2008 …

Retail Visual Assistant Digital Artefact, Neville Knott

Dissertations

Window display, store layout and visual merchandising are defined as the ability to attract and sell to the consumer silently. One of the biggest challenges facing small retail businesses in towns and villages around the globe is how to compete against large multinationals in the visual layout and presentation of their merchandise and shops. One of the key advantages that large retail units have over small ones is professionally merchandised stock incorporated into a strategic spatial layout. The cost of employing a full- or part-time design expert within the field of visual merchandising is not viable for smaller shops, resulting …

The Mother Of Chaos And Night: Kant's Metaphilosophical Attack On Indifferentism, Matthew Allen Kelsey

Dissertations

Kant positions the Critical philosophy as a response to the crisis of metaphysics - a crisis that is still with us. But his diagnosis of that crisis in terms of a struggle between dogmatism, skepticism, and indifferentism is given short shrift in the secondary literature, despite its promise to help us understand Kant's claim that transcendental philosophy represents a radical alternative to these philosophical modi vivendi. After a consideration of Kant's remarks on what philosophy is in general, I argue that all four of these mutually-exclusive ways of philosophizing are best understood as metaphilosophical stances: ways of conceiving of the …

Novel Role Of Erbb-2 In Inhibition Of Jagged-1-Mediated Trans-Activation Of Notch In Breast Cancer, Kinnari Pandya

Dissertations

The ErbB-2 gene is amplified and the resulting protein product overexpressed in 15-30% of breast tumors, and associated with aggressive behavior and poor overall survival. Currently, there are two FDA approved therapies targeting ErbB-2 for the treatment of ErbB-2 positive breast cancer: trastuzumab, a humanized monoclonal antibody is directed against the extracellular domain of ErbB-2 and lapatinib, a dual EGFR/ErbB-2 tyrosine kinase inhibitor. Unfortunately, anti-ErbB-2 therapy resistance remains a major problem in metastatic breast cancer. Our data suggested that gene amplification or overexpression of ErbB-2 inhibits Notch-1 transcriptional activity and trastuzumab or lapatinib increased

Notch-1 transcriptional activity. Furthermore, Notch-1 is …

The Civilian And The War On Terror: Do Norms Shape Strategy?, Sherri Replogle

Dissertations

Despite a growing research agenda centered on issues of civilian immunity, it remains unclear what effect norms protecting civilians have on state behavior, especially democracies. This study asks when and how the civilian immunity norm (CIN) matters, specifically examining how it alters short term strategic choices and even long term doctrines.

Employing a constructivist approach to examine shifting attitudes toward civilians within the military during the Iraq and Afghanistan wars, this study argues that democracies will choose strategic outcomes that strengthen compliance with the CIN when they see the constraining normative environment as a key part of the strategic environment. …

Social And Emotional Learning: An Argument For Religious Pluralism, Debra Mayconich Baron

Dissertations

The purpose of this project is to argue that in order for social and emotional learning (SEL) goals to achieve their intended outcomes for students and society, religious pluralism must be reflected in student instruction. SEL involves the use of evidence-based practices to provide opportunities to develop competencies related to self-awareness, self-management, social awareness, relationship skills, and responsible decision making which are intended to enable students to demonstrate morally appropriate actions and ethical decisions, which I am calling "right behavior."

It is my argument that one's understanding of right behavior embodies both implicit and explicit moral beliefs based on one's …

Effect Of Advanced Age On The Innate Immune Response To Cutaneous Wound Infection, Aleah Lin Brubaker

Dissertations

An estimated 25 billion in US health care expenditure is spent on care of chronic, non-healing wounds. The failure to effectively heal wounds is often compounded by co-morbidities, such as diabetes or obesity. Another major patient population afflicted with chronic wounds are the elderly. Advanced age is associated with a decline in immunologic function that contributes to a poor response to vaccination, infection and tissue injury resulting in prolonged hospital stays and age-related morbidity and mortality. Specifically, clinical observations and laboratory studies have suggested an age-related decline in cutaneous wound healing, marked by protracted wound closure, wound dehiscence and chronic …

Down To Earth Ethics: Exploring Relation And Environmental Responsibility, Matthew Gowans

Dissertations

This dissertation is aimed at exploring the question of direct engagement with the natural world as a way of establishing certain moral and ontological truths, particularly those connected to our current environmental struggles. Contrary to the wave of much of modern Western thinking, Albert Schweitzer, Martin Buber and Aldo Leopold demonstrate an ethics that is relational in nature, action oriented, and bound up in inexpressible wonder. Consequently, these thinkers are also critical of a world which bases the whole of reality solely on the logic of rational investigation and the material facts of science. The heart of ethical responsibility in …

Characterization Of The Novel Response Regulator Sype: A Dual Regulator Of Biofilm Formation And Colonization In Vibrio Fischeri, Andrew Robert Morris

Dissertations

Biofilms, or surface-associated microbial communities encased in a matrix, represent a common mode of growth for many bacterial species. Importantly, biofilms often play significant roles in the association of bacteria with their animal hosts, including promoting attachment to and colonization of host tissues. The symbiosis between the bacterium Vibrio fischeri and its animal host Euprymna scolopes provides a natural model system for investigating the impact of biofilms on host infection. In particular, V. fischeri produces a specific biofilm to successfully initiate host colonization.

Biofilm formation by V. fischeri is a tightly regulated process involving a complex network of regulatory genes. …

Processes Underlying Syntactic Control: Evaluating Linguistically Diverse Children, Vanessa R. Raschke

Dissertations

The current study focused on the mechanisms involved in syntactic awareness development in monolingual and bilingual (English/Spanish-speaking) nine-year-olds. Inclusion of child language brokers (those who translate and interpret for non-English speaking family members) diversified the definition of "bilingual." Previous research has shown bilingual advantages in areas of metalinguistic awareness and executive function (e.g., Bialystok, 2010; Davidson, Raschke, & Pervez, 2010), however, child language brokers have not been distinguished in these studies. These children, due to early language-switching and translation duties, may have differential development of areas of inhibition, cognitive flexibility, and working memory, areas suspected to aid in metalinguistic awareness …

Reaping The "Colored Harvest": The Catholic Mission In The American South, Megan Stout Sibbel

Dissertations

A central paradox marks the story of the Roman Catholic mission in the American South. On one hand, the Church committed itself to providing access to quality education in underserved southern black communities. The establishment of southern Catholic schools for African American children supported the nation's traditional emphasis on education as a prerequisite for economic, social, and political advancement. Insofar as Catholic schools and sisters in the Jim Crow South offered opportunity in communities that otherwise lacked access to education, they demonstrated some of the best qualities traditionally associated with the United States of America.

On the other hand, Catholic …

Environmental Factors Influencing Oxidative Stress In Respiratory Cells, Carresse L. Gerald

Dissertations

Agriculture workers inhale a variety of dusts, gases, microbes and compounds on a daily basis. Several respiratory diseases display inflammation and oxidative stress as key factors of pathogenesis. To better understand the effects of agricultural dusts on the airway there first needs to be characterization of dust components. Thus, we hypothesized that confinement facilities contain high levels of respirable particles, bacteria, and elements of respiratory importance. We further hypothesized that SCF dust alone or in combination with diepoxybutane (DEB) will result in oxidative stress and phytonutrients from the sorrel plant will reduce these effects. Several bacterial species were identified via …

Monitoring Damage Initiation And Growth In Composite Structures By Acoustic Emission Method, Kassahun Mekonnen Asamene

Dissertations

In this dissertation, acoustic emission technique is examined as candidate for monitoring the integrity of polymer matrix structural members. Acoustic emission technique has so far been largely limited to laboratory tests and field applications have been mostly limited to qualification tests of aerospace structures. The lack of quantitative indications of damage in composite structural members associated with the complex nature of damage in these materials has been a limiting factor. Generally, a number of failure modes operate simultaneously at a site of damage, and each of these failure modes generates a different type of acoustic emission signal. In addition, issues …

Cfd Analysis And Design Optimization Of Flapping Wing Flows, Martin Alexander Jones

Dissertations

The main objectives of this research work are to perform the CFD analysis of the 3-D flow around a flapping wing in a gusty environment and to optimize its kinematics and shape to maximize the performance. The effects of frontal, side, and downward wind gusts on the aerodynamic characteristics of a rigid wing undergoing insect-based flapping motion are analyzed numerically. The turbulent, low-Reynolds-number flow near a flapping wing is governed by the 3-D unsteady Reynolds-Averaged Navier-Stokes (URANS) equations with the Spalart-Allmaras turbulence model. The governing equations are solved using a second-order node-centered finite volume method on a hexahedral mesh that …

Use Of Sweet Potato To Develop A Medium For Cultivation Of Lactic Acid Bacteria, Saeed A. Hayek

Dissertations

This study investigated the use of sweet potatoes (Ipomoea batatas) as a basic component to develop a medium for cultivation of lactic acid bacteria (LAB). Extract from baked sweet potatoes was used to form a sweet potato medium (SPM). SPM was supplemented with 4 g/L of each nitrogen source (beef extract, yeast extract, and proteose peptone #3). Lactobacilli MRS was used as a control medium. Ten LAB strains were used to determine the suitability of SPM serving the growth of LAB. Our results showed no significant (p < 0.05) differences in the optical density, maximum specific growth rates, and bacterial populations between MRS and SPM. SPM also maintained higher pH values throughout the incubation period compared to that in MRS. The cost of SPM was 47% less than the cost of MRS. Further step was taken to determine the suitability of SPM serving LAB enzymatic activity. LAB strains growing in SPM showed relatively higher β-glucosidases, acid phosphatase, and phytase activities and lower a-glucosidase compared to that in MRS. Strains of L. reuteri showed the …

Quantitative Analyses Of Acceptable Noise Level For Air Conduction Listening, Bankole K. Fasanya

Dissertations

This study was conducted to develop quantitative models for Acceptable Noise Level (ANL) under air conduction (AC) listening conditions. Experimental results on the effects of frequency bandwidths on ANL under two listening conditions involving earphones and loudspeaker (sound field) with high and low frequencies and babble noise and white noise revealed: (a) there are statistically significant interactions among the background noise types, the background noise frequency bandwidths and signal source; (b) background noise and noise frequency bandwidths have effects on listener discriminability bias toward the noise and the signal intensity; (c) different listening conditions had different ANL thresholds; and (d) …

Understanding The Behavior And Attitude Of Professional Athletes In Saudi Arabia Toward Dietary Supplements, Sulaiman O. Aljaloud

Dissertations

A dietary supplement is defined as a product taken orally that contains a "dietary ingredient" (vitamins, minerals, herbs, amino acids, enzymes, etc.), and is intended to supplement one's diet. Dietary supplements include plant extracts and concentrates from foods. Supplements help provide required nutrients to fulfill nutritional levels for daily training or competitive performance, and can help remedy nutritional deficiencies. Therefore, it is important that sports professionals have a thorough knowledge of these supplement products. However, athletes need to be informed about the use and possible benefits, side effects, and risks associated with the use of dietary supplements. Four objectives guided …

Applying Data Visualisations To Open New Perspectives In Birdwatching, Frank Kendlin

Dissertations

Advances in data analytics for big data have affected many different domains and are providing new insights from these data for their respective communities. One such community is conservation science. A part of section of this community, ornithologists and bird conservationists has at its disposal millions of volunteers willing to contribute to a new ‘big’ data set. This can be achieved by means of new technology and the use of citizen science. This is already underway in North America through the excellent work of the Cornell Laboratory of Ornithology (CLO). This institute has harnessed the technology and the people and …

Validating And Generating Realistic Routes For Individual Human Characters In Virtual Urban Terrain, Gregg Thomas Hanold

Dissertations

The automatic generation of movement routes for autonomous computer controlled entities in virtual environments is an essential and ubiquitous task in simulations of many types and applications. Practically all existing route planning algorithms, many of which are implementations of either the well-known A* algorithm or variants of it, generate routes that are optimized for some route attribute, such as length or movement time. In this research an algorithm is developed that generates routes that are not optimized but are instead realistic, where realism is defined as similarity to routes generated by humans. Before designing the realistic route planning algorithm, four …

Risk Perception In Cardiovascular Disease, Michelle Ellen Block

Dissertations

Cardiovascular disease (CVD) remains among the leading causes of death in the United States despite widespread knowledge about risk factors as well as effective primary prevention strategies. Risk perception is a complex phenomenon that plays an important role in how persons view disease and ultimately how they make health behavior choices. This study is supported by the knowledge that few studies have examined how persons perceive cardiovascular risk or the variables thought to contribute to the formation of risk perception.

Purpose: The purpose of this study was to examine how accurately persons perceive personal risk for cardiovascular disease and identify …

Visual Analysis Of E-Textbooks For Senior High School In Indonesia, Ouda Ena

Dissertations

The purpose of the study was to evaluate the visual images used as illustrations in the English electronic textbooks for grades ten, eleven, and twelve in Indonesia. Qualitative visual content analysis was employed as the methodology of the research. The analysis focused on whether these e-textbooks accommodated the religious, gender, ethnic, and socioeconomic diversity of the students. These four aspects of cultural diversity that influenced students learning in Indonesian contexts were crucial to examine because the students were so diverse as results of the geographical conditions and historical background of Indonesia. Eight English e-textbooks were examined. First, the result showed …