Digital Commons Network^™

Solid State Forms Of 2-{4-[(3s)-Piperidin-3-Yl]Phenyl}-2h-Indazole-7-Carboxamide Salts And Processes For Preparation Thereof, Srinivasan Thirumalai Rajan, Sagyam Rajeshwar Reddy, Kammari Bal Raju, Garai Abhijit, Padigapaty Shiva Reddy, Msn Laboratories Private Limited, R&D Center, Hyderabad, India.

Defensive Publications Series

The present invention provides solid state forms of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide salts and processes for preparation thereof.

2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide of the present invention is represented by the following structural Formula-1.

Formula-1

Summarization Framework For Sharing And Contextual Previews, Thomas Nont Boonsiri, Siddhartha Sivakumar, Salvador Guerrero Ramos, Lan Julia Liang, Elizabeth Martinez

Defensive Publications Series

A system is disclosed that provides a summary of web-based content. Web-based content comprising text-based content is received by a browser. A portion of the text-based content is processed through a large language model to determine a summary of the portion of the text-based content. The portion is determined according to a threshold token limit. The summary is provided for display via a user interface.

Implementations of the present disclosure are generally directed to user device generation of a summary of web-based content (webpages, text, images, media files, etc.) via a generative model, such as a large language model (LLM). …

Solid State Forms Of L-Arginine, (3r)-7-[[4-Cyclopentyl-3-(Trifluoromethyl)Phenyl]Methoxy]-1,2,3,4 Tetrahydro Cyclopent[B]Indole-3-Acetate And Processes For Preparation Thereof, Srinivasan Thirumalai Rajan, Sagyam Rajeshwar Reddy, Kammari Bal Raju, Garai Abhijit, Edulakanti Jhansi, Msn Laboratories Private Limited, R&D Center, Hyderabad, India.

Defensive Publications Series

The present invention provides new solid state forms of L-Arginine, (3R)-7-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-1,2,3,4-tetrahydrocyclopent[b]indole-3-acetate represented by the following structural formula-1a and processes for preparation thereof.

The present invention also provides various processes for the preparation of amorphous form of L-Arginine, (3R)-7-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-1,2,3,4-tetrahydrocyclopent[b]indole-3-acetate.

The present invention further provides pharmaceutical compositions comprising solid state forms of compound of formula-1a.

Formula-1a

Method And System For Tap To Customer’S Own Device To Authenticate A Card, Esha Dutta, Thomas D. Rapkoch, Rhodora Enrijoy H. Martin, Mark Rigby, Geraldine Mitchley

Defensive Publications Series

Present disclosure provides a method and system for tap to customer’s own device to authenticate a card and this process is implemented in various use cases such as tap to activate a card, tap to confirm a card, tap to add/provision a card and the like. For instance, the tap to authenticate a card includes sending a request by the user to load new card credentials to wallet operator application that transmits a request to perform a financial activity (eg: provisioning card) including EMV cryptogram to issuer mobile gateway. The issuer mobile gateway requests for the issuance of a token …

Cross-Lingual Prosody Preservation In Speech Generation Applications, Daniel V. Klein, Paul Mccartney

Defensive Publications Series

This disclosure describes a data collection approach to obtain a high-quality, paired prosody dataset to support cross-lingual prosody translation in voice dubbing and other speech generation applications. Current datasets lack the nuanced prosodic features that are essential for natural and expressive cross-lingual speech synthesis, resulting in synthetic speech that often sounds flat or lacks emotional resonance. Per techniques of this disclosure, audio spoken by professional voice actors or other individuals proficient in a language is recorded in various languages. Paired recordings of matching content are available in the collected dataset. The recordings capture nuanced prosody such as rhythm, emotion, and …

Safe, Robust, And Graceful Handling Of Stale Or Offline Remote Sensors, Eric Burger, Ernie Yang

Defensive Publications Series

Remote sensors for a control device such as a thermostat enable it to adjust the temperature at the location of the occupants of the home or office. If the thermostat misses one or more remote temperature readings, temperature control can be unsatisfactory. This disclosure describes techniques that forestall thermostat problems such as stale sensors and outdated readings arising from lapses in connectivity between a thermostat and its remote sensors. A robust, fail-safe mechanism is described that detects and mitigates connectivity problems by reverting control to a local temperature sensor if the requested remote sensors provide invalid or stale data. A …

Process For The Preparation Of Tirzepatide, Srinivasan Thirumalai Rajan, Ghojala Venkat Reddy, Mallepally Venkat Reddy, Suryapeta Srinivas, Nidadavolu Chandrasekhar, Msn Laboratories Private Limited, R&D Center, Hyderabad, India.

Defensive Publications Series

ABSTRACT

Title of the invention: Process for the preparation of Tirzepatide

The present invention relates to a process for the preparation of Tirzepatide represented by the following structural formula-1.

Formula-1

Rack Bus Bar Connector With Built-In Hotswap Features, N/A

Defensive Publications Series

The technology described in this paper relates to a hotswap method for high-voltage rack systems such as ±400 V or 0-800 V systems by leveraging controlled and sequenced insertions of different power connector pins to achieve safe and efficient power connector insertion and removal. The power connector may include multiple pins of various lengths, which allows each pin to establish an electrical connection to a bus bar in a pre-defined order. For example, ground pins and pre-charger pins are electrically connected to the bus bar before the main power pins are electrically connected to the bus bar. The pre-charger pins …

Wireless Broadcast Sharing In Multi-Controllermulti-User Environments, Henry Salvatore Savage

Defensive Publications Series

This publication describes a vehicle computing system (e.g., a head unit, in-vehicle entertainment system, infotainment system, etc.) that may automatically switch from outputting audio to a single computing device using a wireless point-to-point protocol to outputting audio to two or more computing devices using a wireless broadcast protocol. The vehicle computing system may include multiple modules for controlling wireless connections (e.g., multiple BLUETOOTH controllers, WIFI controllers, etc.). Each user in the vehicle may have wireless listening devices (e.g., wireless headphones, speakers, earbuds, etc.) connected to at least one of the wireless controllers. For example, a user may have wireless headphones …

Determine Hfto Damper Utilization Through Amplitude Dependent Damping Mechanism, Baker Hughes Company

Defensive Publications Series

High Frequency Torsional Oscillation (HFTO) is a particularly damaging vibration that is induced during drilling of prone formations with PDC bits. Adding damping has been found to be a proper method to mitigate HFTO. There are different damping mechanisms available and patented. In reality the damping is amplitude dependent (modal amplitude of the HFTO amplitude). Some downhole vibration damper tools (HFTO damper) are extremely nonlinear and have a dedicated dependency between the damping and the amplitude. The required damping is a very important information. With the required damping the length or radial dimensions of a HFTO damper, for example an …

Prosodic Alignment Via Gradient Descent, Kb Sriram

Defensive Publications Series

This paper describes a gradient descent-based approach to prosodic alignment in automatic dubbing using gradient descent optimization. The technique addresses the challenge of synchronizing dubbed speech with the original speaker's cadence of phrases and pauses when replacing speech in a video with a different language. By framing prosodic alignment as an optimization problem solvable through standard machine learning (ML) workflows, the fitness function can be expressed using numeric libraries with gradient descent directly serving as the solver.

This approach handles challenges in speech pacing, word ordering inversions, and pauses during translation while ensuring natural timing of dubbed content. The technique …

Assessing Road Lighting Conditions Using Speed Variation Analysis, Priyank Garg

Defensive Publications Series

Currently, digital maps and navigation systems do not provide sufficient information about lighting conditions for roads and lanes. The lack of reliable information can negatively impact route selection and driving speed if a road is poorly lit). This disclosure describes techniques to automatically determine the lighting level of a road or road segment by analyzing speed variation of vehicles that traverse it at late night (when it is dark) and early morning (when there is adequate light), under otherwise similar conditions (traffic levels, road surface quality, etc.). A significant difference in speed between these periods suggests poor road lighting, as …

Automatically Surfacing Navigation Assistance In Driving Contexts, Ilya Levin, Yarin Aidelman, Arie Orlovsky, Or Abramov, Itamar Besor

Defensive Publications Series

While digital map and navigation applications provide useful assistance when a user is driving, the user needs to explicitly seek guidance from these applications. If the user chooses to drive without assistance, the user may miss out on useful information such as congestion alerts, faster alternative routes, etc. This disclosure describes techniques, implemented with user permission, to automatically detect a driving context and proactively surface useful notifications. The driving context can be detected based on analyzing connection type and name associated with Bluetooth connections established by a mobile device that runs the navigation application. Additional user-permitted factors such as current …

The Composite Projection System That Utilizes 4 Projection Configurations To Achieve A Higher Pixel Dense Central Virtual Content Viewing Area And At The Same Time That Utilizes 4 Projection Configurations To Achieve A Moderately Pixel Dense Surrounding Virtual Content Viewing Area., Punarjeewa Abeysekera

Defensive Publications Series

This paper describes a composite projection system that utilizes 4 projection configurations to achieve a higher pixel dense central virtual content viewing area and at the same time that utilizes 4 projection configurations to achieve a moderately pixel dense surrounding virtual content viewing area. The entire composite projection system will consists of 4 composite projection configurations and 8 beam splitter configurations. And each composite projection configuration will contain 2 convex lens stacks, 2 light blocking covers and 2 video projection display areas. The composite projection system will have the capability to project a composite virtual content viewing area onto the …

Mechanical Rotary Ui, Versuni Holding B.V.

Defensive Publications Series

A versatile and cost effective user interface that can be used to navigate and select a function of the appliance with only a knob. Navigation of the menus is through rotation of knob and selection is by pressing. A non-rotating fixed display is also integrated at the centre to provide visual UI to the consumer.

Crystalline Form Of 1-{(2s,5r)-2-Methyl-5-[(7h-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Amino]Piperidin-1-Yl}Prop-2-En-1-One 4-Methylbenzene-1-Sulfonic Acid Isonicotinamide, Msn Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; Sagyam Rajeshwar Reddy; Kammari Bal Raju; Garai Abhijit

Defensive Publications Series

Abstract

Title of the Invention: Crystalline form of 1-{(2S,5R)-2-methyl-5-[(7H-pyrrolo[2,3-d] pyrimidin-4-yl)amino]piperidin-1-yl}prop-2-en-1-one 4-methylbenzene-1-sulfonic acid Isonicotinamide.

The present invention relates to crystalline form of 1-{(2S,5R)-2-methyl-5-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}prop-2-en-1-one 4-methylbenzene-1-sulfonic acid Isonicotinamide of formula-1.

Formula-1

An Improved Process For The Preparation Of Difelikefalin Acetate, Msn Laboratories Private Limited, R&D Center, Srinivasan Thirumalai Rajan, Ghojala Venkat Reddy, Mallepally Venkat Reddy, Suryapeta Srinivas, Nidadavolu Chandrasekhar

Defensive Publications Series

ABSTRACT

Title of the Invention: An improved process for the preparation of Difelikefalin acetate

The present invention relates to an improved process for the preparation of Difelikefalin acetate compound of formula-1, wherein 1.0 ≤ x ≤ 2.0.

Formula-1

Novel Crystalline Forms Of Elacestrant Dihydrochloride And Processes For Their Preparation, Msn Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; Sagyam Rajeshwar Reddy; Kammari Balraju; Garai Abhijit; Kamutam Sathish

Defensive Publications Series

The present disclosure relates to novel crystalline forms of Elacestrant dihydrochloride which is chemically known as (6R) -6- (2- (N- (4- (2-(ethyl amino) ethyl) benzyl) -N- ethyl amino) - 4- methoxy phenyl) - 5, 6, 7, 8-tetrahydrona phthalen-2-ol dihydrochloride of formula-1a and their processes for the preparation thereof

Formula-1a.

The present disclosure also relates to novel salts of Elacestrant of Formula-1, represented by the following structural formula and processes for the preparation thereof.

Formula-1.

High Density Interconnect Chip On Board, N/A

Defensive Publications Series

This paper is generally directed to systems, methods, and devices that facilitate direct attachment of a high density silicon or semiconductor chip to an embedded coreless printed circuit board (“PCB”). The technology disclosed provides an assembly and method for manufacturing directed to a new coreless PCB (“CPCB”) with an embedded coreless substrate, as well as systems incorporating CPCBs. The CPCB enables direct bonding of a high density silicon chip (“HDSC”) to the CPCB as the last step in the system manufacturing process. This is in contrast to the traditional manufacturing process of first bonding an HDSC (with or without an …

Securing The Future Of Ai: A Deep Compliance Review Of Anthropic, Google Deepmind, And Openai Under Soc 2, Iso 27001, And Nist, Ramkumar Bharathan

Defensive Publications Series

As foundation models like Claude, Gemini, and OpenAI become integral to enterprise AI solutions, the need for rigorous, standards-aligned security evaluation grows. This paper presents an expert-level comparative audit of the SOC 2 controls implemented by Anthropic, Google DeepMind, and OpenAI, drawing from public attestations, model cards, and technical documentation. Going beyond traditional compliance, the assessment incorporates frameworks from ISO 27001, NIST, and AI-specific risk models to benchmark each provider’s security maturity across five domains: organizational governance, infrastructure controls, operational security, data protection, and AI-specific safeguards.

Key findings indicate that Google demonstrates enterprise-grade maturity with advanced automation, zero-trust architecture, and …

Vibration Damping By Nebulizing A Liquid Into An Aerosol Mist, Baker Hughes Company

Defensive Publications Series

The typical liquid damper forces a viscous liquid through a small orifice and its damping is dominated by viscous losses that convert mechanical energy to heat and such dampers can be used in drill strings. In this disclosure, the liquid damping is dominated by energy absorbed when a high-surface-tension liquid is nebulized into a mist of many fine droplets that, taken together, have far higher surface area than the original liquid. Here, the preferred high-surface-tension liquid is gallium both for its surface tension and its density. Gallium’s surface tension is 11 times that of water (which must be kept pressurized …

Method To Adapt Different Downhole Drilling Tool Bus Systems, Baker Hughes Company

Defensive Publications Series

The invention relates to a constructive method for adapting a downhole tool to different downhole bus systems in order to be used in a bottom hole assembly with the respective downhole bus systems used. The adaptation relates to a possibly necessary mechanical adaptation to the different connector systems of the bus systems and to the adaptation of the downhole tool to the respective power and communication system used.

Filtering Low Quality Query Recommendations, Jap Leen Kaur Jolly, Karan Rai, Paritosh Shroff, Stephanie Saade

Defensive Publications Series

Some search engines provide query recommendations that suggest additional queries related to a user’s original query. Low-quality query recommendations can be irrelevant to the user’s information need and degrade the user experience. This disclosure describes techniques to filter low-quality query recommendations such that they are not displayed to users. The filtering is performed by evaluating a set of candidate query recommendations based on query recommendability scores along three quality-related dimensions - content, formulation, and flavor. Additionally, updateworthiness for a query recommendation can also be used. Implementation of the techniques can raise the quality, utility, and trustworthiness of query recommendations and …

Offloading Data Center Computational Workloads To User Devices, Shubham Saini

Defensive Publications Series

This disclosure describes techniques for providers of distributed computing services to utilize idle computing resources associated with user devices. With user permission and express consent, software is installed on available user device(s) that can enable creation of a virtual environment on each user device. The virtual environment on the user device is configured such that the user has no visibility into data associated with the data center usage, and the data center operator has no visibility and/or access to user data that is stored on the user device. When a computational workload is received, it is determined by a data …

Improved Flow-Rate Control And Space Optimization In Liquid Cooling Systems, N/A

Defensive Publications Series

This disclosure describes techniques for improved flow-rate control in liquid cooling systems that are used in thermal management of data center racks. Per techniques of this disclosure, proportional solenoid valves (also known as solenoid control valves) are used for flow-rate control in data center liquid cooling applications. By adjusting the PWM duty cycle, a control system can control the liquid flow to achieve a target temperature of a device being liquid cooled. In some implementations, the valve is placed directly inside the server tray and control signals to perform flow-rate control are provided by a tray-level motherboard. In some implementations, …

Numerical Method For Identification Of Processors With High Power Consumption And Frequency Throttling, N/A

Defensive Publications Series

When a processor - central processing unit (CPU) - in a data center hits a power limit, the processor automatically throttles the operating frequency. Since such CPUs are operating at their power limits, no fault mechanisms are tripped, such that the only consequence of such slow CPUs is degraded user experience. This disclosure describes techniques to screen a fleet of CPUs to identify and service CPUs that are at their power-consumption limits and are throttling their operating frequencies. During CPU throttling, the operating frequency drops but the current consumption remains steady, such that the ratio of current consumption to CPU …

Training A Machine Learning Model To Read Illegible Barcodes, N/A

Defensive Publications Series

Illegible barcodes can hinder use of barcodes in many contexts. This document describes a machine learning (ML) model trained to read illegible barcodes. The training dataset used to train the ML model comprises illegible barcodes (e.g., having low contrast, small size, wear-and-tear) and corresponding groundtruth. The ML model is trained to generate a legible version of the barcode. During training, the model output is compared with the groundtruth and the difference is fed to a loss function to adjust the weights of the model. In field use, a user can capture a photo of an illegible barcode and access the …

A Machine With Expandable Hinge, Hp Inc

Defensive Publications Series

An expandable hinge with magnetic control is designed for dual-screen notebooks to eliminate gaps when the keyboard is removed. The hinge adjusts its axis rotation based on the keyboard’s presence, ensuring smooth 180° opening and a flush closure.

Benzgalantamine Gluconate Crystalline Form P, Anonymous

Defensive Publications Series

The present study provides a process for the preparation of Benzgalantamine Gluconate Crystalline “Form P” as per the process reported in WO 2014016430 A1.

Teaching Ai Agents By Error Correction On Plans, Anand R. Iyer, Kimberly Milam

Defensive Publications Series

It is important for enterprises to be able to trust artificial intelligence (AI) agents to align with their domain knowledge and brand identity, and to adhere to design, business, and usability goals. This disclosure describes techniques that enable artificial intelligence (AI) application developers to steer AI agent actions by correcting mistakes via simple user interface (UI) interventions. Incorrect AI agent plans that are automatically generated using an LLM can be manually fixed. The corrected plan can be added as an example to an example store. New tasks for the LLM can leverage corrective examples stored in the example store. Customers …