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การพัฒนาสารเคลือบป้องกันการติดเชื้อจากซิลเวอร์คอปเปอร์ซีโอไลต์สำหรับวัสดุหนังหุ้ม, จิตตมาศ ตรีรัตนภรณ์
การพัฒนาสารเคลือบป้องกันการติดเชื้อจากซิลเวอร์คอปเปอร์ซีโอไลต์สำหรับวัสดุหนังหุ้ม, จิตตมาศ ตรีรัตนภรณ์
Chulalongkorn University Theses and Dissertations (Chula ETD)
เนื่องจากสถานการณ์การระบาดใหญ่ของ Covid-19 ความเป็นไปได้ในที่จะติดเชื้อจากพื้นผิวสัมผัสตามวัสดุที่ต้องเผชิญในชิวิตประจำวันได้รับความกังวลอย่างมาก หนึ่งในวัสดุที่ใช้หุ้มเพื่อสัมผัสที่สำคัญมักจะทำจากวัสดุหนังเช่นเฟอร์นิเจอร์บ้านและเบาะรถยนต์ เพื่อหลีกเลี่ยงการติดเชื้อจึงมีการใช้สเปรย์แอลกอฮอล์ป้องกันไวรัส อย่างไรก็ตามประสิทธิภาพของสเปรย์มีผลต้านเชื้อในเวลาอันสั้นและยังทำให้ผิวเคลือบวัสดุเสื่อมสภาพง่ายอีกด้วย เพื่อยืดอายุการใช้งานของวัสดุหนังและยืดอายุประสิทธิภาพการต้านเชื้อ สารเคลือบผิวด้วยไอออนทองแดงเงินในโครงสร้างซีโอไลต์ (Ag+CuZeolite) จึงถูกพัฒนาขึ้นด้วยการดัดแปลงไอออนในโพรงซีโอไลต์ให้มีอนุภาคใหญ่ขึ้นเพื่อความเสียรภาพของการต้านเชื้อ ไอออนทองแดงเงินในโครงสร้างซีโอไลต์ที่เปลี่ยนเป็นอนุภาคนาโนถูกเตรียมโดยการลดไอออนของเงินที่ชุบด้วยโซเดียมโบโรไฮไดรด์และกรดแอสคอร์บิค อัตราส่วนของสารรีดิวซ์ต่อซีโอไลต์ในระหว่างกระบวนการลดได้รับการปรับให้เหมาะสมที่สุด จากการสังเกตุด้วยSEM-EDX พบว่าโครงสร้างหลักของซีโอไลต์ถูกทําลายในขั้นต้นเมื่อใช้อัตราส่วนโซเดียมโบโรไฮไดรด์สูง ในทางกลับกันการลดกรดแอสคอร์บิคบน Ag + ที่ชุบในซีโอไลต์จะรักษาโครงสร้างหลักไว้ Ag+CuZeolite มีประสิทธิภาพต้านเชื้อแบคทีเรียE. coli (แกรมลบ) ตามาตรฐานASTM E219-10 ที่ดีกว่า AgNPs ใน CuZeoliteที่ถูกรีดิวซ์จากNaBH4และกรดแอสคอร์บิคตามลำดับ การเคลือบ Ag+CuZeolite เพียงแค่3% ต่อสารละลายเคลือบโพลียูรีเทนบนหนังได้รับการประเมินโดยใช้ ISO21702 ของ Sars CoV2 ซึ่งพบว่ามีประสิทธิภาพถึง99.99% ของการต้านเชื้อไวรัส อย่างไรก็ตามความทนทานของต้านเชื้อไวรัสนั้นลดลงอย่างมากภายใต้การสัมผัสสารละลายอัลคาไลน์ ซึ่งเป็นตัวแทนของเหงื่อคน
The Urinary Proteomic Analysis And The Vitamin D Receptor Polymorphisms In Dogs With Calcium Oxalate Urolithiasis, Sumonwan Chamsuwan
The Urinary Proteomic Analysis And The Vitamin D Receptor Polymorphisms In Dogs With Calcium Oxalate Urolithiasis, Sumonwan Chamsuwan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Calcium oxalate (CaOx) urolithiasis is one of the most common stone components which frequently occurs in both humans and dogs. Hypercalciuria is one of the predisposing factors commonly found in both people and dogs with calcium urolithiasis. The genetic factors are also involved with the pathogenesis of stone formation, and the relationship between calcium handling and vitamin D receptor (VDR) polymorphisms has been demonstrated to be related to calcium urolithiasis in human populations. Moreover, some urinary proteins may be involved in the process of stone formation. The present study aimed firstly to evaluate the relationship between VDR polymorphism in dog …
Closed-Form Formulas For Conditional Moments Of Generalized Cox-Ingersoll-Ross Processes, Phiraphat Sutthimat
Closed-Form Formulas For Conditional Moments Of Generalized Cox-Ingersoll-Ross Processes, Phiraphat Sutthimat
Chulalongkorn University Theses and Dissertations (Chula ETD)
Cox-Ingersoll-Ross (CIR) process, introduced in 1985, is a one factor model used to describe the evolution of interest rate and pricing the financial derivatives. It was later extended to have time-dependent parameters called the extended CIR (ECIR) process, which is more widely studied and used in a variety of applications. The generalized versions of CIR process are also studied and investigated for more applications in finance. However, most of these applications rely on the knowledge and properties of conditional expectations and moments, which most of them are not yet fully developed into closed form. In this work, we propose closed-form …
Enhanced Heterogeneous Network Model With Ensemble Similarities For Identifying Protein Targets Of Drugs, Piyanut Tangmanussukum
Enhanced Heterogeneous Network Model With Ensemble Similarities For Identifying Protein Targets Of Drugs, Piyanut Tangmanussukum
Chulalongkorn University Theses and Dissertations (Chula ETD)
Currently, computational identification of drug target proteins is widely used to help saving cost and time for drug discovery and development. One of the most efficient approaches is a prediction of drug-target interactions based on similarity scores between drugs and target proteins. Despite various data about drugs and targets extensively available, only chemical structures and protein sequences are mostly used to compute drug-drug and target-target similarity scores, respectively. In this thesis, the Forward similarity integration (FSI) Framework is proposed for systematically integrating multiple similarity measures to construct a heterogeneous network propagation model with a suitable similarity integration. Seven drug-similarity measures, …
Newton Iterative Algorithm For Polynomial Modular Inversion Modulo Xn±1 For Some Patterns Of N, Samakorn Sripatthanakul
Newton Iterative Algorithm For Polynomial Modular Inversion Modulo Xn±1 For Some Patterns Of N, Samakorn Sripatthanakul
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis presents an algorithm for computing the modular inverse of a polynomial in a ring of polynomials over a finite field $\mathbb{F}_q$ with a characteristic $p$. Given a polynomial $f$ and a natural number $r$, by applying the idea of the Newton iteration algorithm, the fast division algorithm used to find the inverse of $f$ under modulo $x^{p^r}-1$, $x^{p^r}+1$, $x^{2p^r}-1$ and $x^n-1$ where $n=2^r d$ for some $r,d\in\mathbb{N}$, is established. The cost analysis for these cases show that the algorithm has the computational complexity of $\mathcal{O}(n \log n)$ which is more efficient than the Half-GCD algorithm in terms of …
Scheduling Of Pressing Process In Multi-Layer Printed Circuit Board Manufacturing Via Milp And Heuristic, Teeradech Laisupannawong
Scheduling Of Pressing Process In Multi-Layer Printed Circuit Board Manufacturing Via Milp And Heuristic, Teeradech Laisupannawong
Chulalongkorn University Theses and Dissertations (Chula ETD)
The pressing process aims to press the panel which is the stack of materials to form a multi-layer printed circuit board (PCB). This process is a part of multi-layer PCB fabrication and can be considered as a scheduling problem with the objective of minimizing the makespan. In this dissertation, two mixed-integer linear programming models (Models 1 and 2) and a three-phase-PCB-pressing heuristic (3P-PCB-PH) algorithm for scheduling the pressing process are presented. Model 2 is an improvement of Model 1 in terms of the model size and the dimensionality of some decision variables. Both models and the 3P-PCB-PH algorithm are used …
Special Types Of Tolerance And Control Solutions To System Of Interval Linear Equations, Warintorn Pongsumrankul
Special Types Of Tolerance And Control Solutions To System Of Interval Linear Equations, Warintorn Pongsumrankul
Chulalongkorn University Theses and Dissertations (Chula ETD)
In this thesis, we study a system of interval linear equations of the form Ax=b which includes an interval coefficient matrix and an interval right hand side vector. There are many types of solutions of this system which serve the different semantics in real-life situations such as tolerance and control solutions. We pay attention to the semantics that some boundaries of intervals are important. Moreover, we combine these semantics together with the semantics of tolerance and control solutions in order to present the new types of solutions to Ax=b, called special tolerance left, special tolerance right, special control left and …
In Silico And In Vitro Screening Of Newly Designed Compounds Against Coxsackivirus A16 And Enterovirus A71, Amita Sripattaraphan
In Silico And In Vitro Screening Of Newly Designed Compounds Against Coxsackivirus A16 And Enterovirus A71, Amita Sripattaraphan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Outbreaks of hand, foot, and mouth disease (HFMD) occur around the world. It is caused by the Coxsackievirus-A16 (CV-A16) and Enterovirus-A71 (EV-A71) that belong to the Enterovirus genus. Unfortunately, neither an anti-HFMD drug nor a vaccine is currently available. Rupintrivir, one of the drug candidates for HFMD treatment, has been attractive for the development of its analogs with broad biological activities. This drug is an inhibitor for 3C protease of CV-A16 and EV-A71, an enzyme that plays a crucial role in the viral replication process. ). In the present study, we focused on designing 50 novel rupintrivir analogs against CV-A16 …
In Silico And In Vitro Studies On Inclusion Complexation Of Anthraquinone Derivatives With Beta-Cyclodextrin Derivatives, Amy Oo
Chulalongkorn University Theses and Dissertations (Chula ETD)
In this study, we investigated the cytotoxicity of 6 anthraquinones (ventilanone K, emodin, chrysophanol, aurantio-obtusin, 1-O-methyl-2-methyoxychrysophanol, and questin) toward A549 lung cancer cells and emodin (ED) exerted the most potent cytotoxicity with IC50 value of 34.27 ± 1.27 µM. The anti-cancer activity of ED has been well reported but its usage in practical applications has been restricted due to its poor solubility. To address this issue, we performed inclusion complexation of ED with βCD, hydroxypropyl-β-cyclodextrin (HPβCD), 2,6-di-O-methyl-β-cyclodextrin (DMβCD), and sulfobutylether-β-cyclodextrin (SBEβCD) theoretically using molecular dynamics simulations and experimentally using phase solubility study and cytotoxicity screening toward cholangiocarcinoma cell lines (KKU-213A …
Urban Attraction Policies For Science And Technology Talent: Case Studies Of Chinese Cities, Yuxuan Shan
Urban Attraction Policies For Science And Technology Talent: Case Studies Of Chinese Cities, Yuxuan Shan
Chulalongkorn University Theses and Dissertations (Chula ETD)
In the modern era of rapid socio-economic development, high-skill human resources, especially science and technology talents, have become pivotal to promoting urban development. For decades, there has been fierce competition among local governments in China to issue more competitive policies to attract talents to live and work in the cities. As China’s first-tier cities, Beijing, Shanghai, Guangzhou, and Shenzhen have tried to achieve the goal of becoming a scientific and technological innovation center with global influence. Thus, these cities have implemented their local policies on talents. This study adopts a case study research method to analyze the contexts of local …
Effect Of A Combination Of Altrenogest And Double Pgf2alpha Administrations On Farrowing Variation, Piglet’S Performances And Colostrum Igg, Preechaphon Taechamaeteekul
Effect Of A Combination Of Altrenogest And Double Pgf2alpha Administrations On Farrowing Variation, Piglet’S Performances And Colostrum Igg, Preechaphon Taechamaeteekul
Chulalongkorn University Theses and Dissertations (Chula ETD)
The aims of the present study were to investigate the effect of altrenogest treatment from 109 to 112 days of gestation in combination with double intramuscularly of PGF2alpha administrations at 113 days of gestation on the variation of farrowing in sows and its side effects on the sow colostrum yield, colostrum IgG, newborn piglet characteristics and piglet survival rate until seven days of postnatal life. In total, 193 sows were randomly allocated according to parity number into two groups, i.e. control (n = 95) and treatment (n = 98). The control sows were allowed to farrow naturally. The treatment sows …
Social Capital And Myanmar Urban Migrant Workers’ Job Seeking In Thailand During The Covid-19 Pandemic, Andrew Wai Phyo Kyaw
Social Capital And Myanmar Urban Migrant Workers’ Job Seeking In Thailand During The Covid-19 Pandemic, Andrew Wai Phyo Kyaw
Chulalongkorn University Theses and Dissertations (Chula ETD)
During the COVID-19 pandemic, many production sectors in Thailand encountered economic difficulties. The economic impacts of the pandemic have affected all people in the economy, including migrant workers. Especially urban migrant workers might have been the most affected by the pandemic. They have faced insecure livelihoods caused by losing jobs, loss of income, and difficulties in finding new jobs. Myanmar workers are the largest population among migrant labor forces in Thailand. Various literature shows that social capital has always been supportive as a valuable and critical resource contributing to well-being, especially during times of crisis and socio-economic change. So, urban …
A Systematic Review Of Smart City Development Policies In Chinese Cities, Mingqing Yin
A Systematic Review Of Smart City Development Policies In Chinese Cities, Mingqing Yin
Chulalongkorn University Theses and Dissertations (Chula ETD)
Urban development plays a vital role in enhancing the productivity, competitiveness, and economic growth of a country. Nowadays, more than half of the world's population lives in cities. By 2050, it is estimated that around 70 percent of the population will live in cities. China is one of the countries with the most rapid urbanization in the world. The first-tier cities comprising Beijing, Shanghai, Guangzhou, and Shenzhen are the most developed cities in China in terms of infrastructure development and economy. These cities are the major economic, political, and cultural engine of the country as well as role models of …
Vacant Shophouse Buildings In Bangkok: The Root Causes And Strategic Options, Nabila Imam
Vacant Shophouse Buildings In Bangkok: The Root Causes And Strategic Options, Nabila Imam
Chulalongkorn University Theses and Dissertations (Chula ETD)
Since the old-fashioned shophouse buildings cannot act in response to the urban sprawl and changing lifestyles of Bangkok, progressively they are converting into partially vacant buildings or sometimes they go off entirely unoccupied for an indefinite period of time. A noteworthy number of fully or partially vacant shophouse buildings can be found in every nook and corner of the city. These vacant shophouses act as the "voids" in the neighborhood, posing a threat to potential housing community development, economic opportunity, environmental health, and public safety within the city. However, these so-called "voids" might offer a great opportunity for the city …
The Impact Of Tourism On Urban Renewal Through Stakeholders’ Perspective: A Case Of Post-Earthquake Urban Renewal In Kathmandu Valley In The Wake Of Covid 19, Shitu Maharjan
Chulalongkorn University Theses and Dissertations (Chula ETD)
In an increasingly urbanized world, there is a growing awareness of the impact of disasters in urban environments and of the complex challenges in rebuilding urban areas following large-scale disasters (Daly, et al., 2017). A magnitude 7.8 earthquake and its subsequent aftershocks struck Nepal almost seven years ago on April 25, 2015, triggering a huge humanitarian disaster. The earthquake caused significant socioeconomic destruction, from which the country is yet to recover. The initial years of post-earthquake rehabilitation were slow; eventually, it picked up speed and accomplished some important reconstruction in historic sites. However, not all locations received the same amount …
Assessment Model Of University Innovation Ecosystems In Asean, Jirawan Chaipongpati
Assessment Model Of University Innovation Ecosystems In Asean, Jirawan Chaipongpati
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study is concerned with the development, testing, and commercialization of an assessment model for university innovation ecosystems, for use in Asian universities. The research was motivated by a combination of two key issues, including the relatively new introduction of innovation as the university objective in Asian universities, and the lack of inward-focused, development-oriented models for university innovation ecosystems. The assessment model is designed to both standardize innovation ecosystem assessment, and provide internal developmental information for universities on a path toward innovation and entrepreneurial universities. The preliminary assessment was developed through reference to several existing innovation ecosystem assessment models, which …
Evaluating The Impact Of Vertical Accessibility Performance To Bangkok Mass Transit Stations On The Travel Behavior Of Elderly Passengers, Yoon Ei Kyaw
Chulalongkorn University Theses and Dissertations (Chula ETD)
The Bangkok Mass Transit System (BTS) sky-train is one of Bangkok's primary public transit modes to alleviate traffic congestion among many daily users. Regarding urban mobility, inclusivity is crucial. According to a 2016 World Bank report, by 2040, more than a quarter of the Thai population will be 65 or older. If the elderly could move around the city with greater ease, they would be able to participate more in society and have access to health care regardless of their age. However, news and reports demonstrated the BTS sky train's limited accessibility for persons with limited mobility. In this study, …
Assessment Of Left Atrial Function In Cats With Arterial Thromboembolism By Using Two-Dimensional Speckle Tracking Echocardiography, Jidapa Tosuwan
Assessment Of Left Atrial Function In Cats With Arterial Thromboembolism By Using Two-Dimensional Speckle Tracking Echocardiography, Jidapa Tosuwan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Feline arterial thromboembolism (ATE) is an acute and distressing clinical presentation with high mortality and poor prognosis. ATE may be related to cardiogenic causes such as the underlying myocardial disease or non-cardiogenic causes. Echocardiography is the routine diagnostic tool to evaluate cardiac structural changes and myocardial function in cats. Two-dimensional speckle tracking echocardiography (2D-STE) is a novel ultrasound modality based on 2D echocardiographic images, that allows multidirectional active deformation assessment and provides comprehensive information on myocardial contractile properties and function. 2D-STE echocardiography has been used to estimate the strain and strain rate of left atrial myocardial deformation in humans, dogs …
Genetic Characterization And Strain Differentiation Of Feline Calicivirus Among Cat Population In Thailand By High Resolution Melting Analysis, Kannika Phongroop
Genetic Characterization And Strain Differentiation Of Feline Calicivirus Among Cat Population In Thailand By High Resolution Melting Analysis, Kannika Phongroop
Chulalongkorn University Theses and Dissertations (Chula ETD)
Feline calicivirus (FCV) is wildly known as one of the significant causative viral pathogens causing self-limited upper respiratory tract and oral disease in cats. In the last decade, severe FCV form, as named a virulent systemic feline calicivirus (VS-FCV), has distinctly emerged worldwide even though commercially available vaccines for FCV are typically used in Thai cats. However, the data of either prevalence or molecular characterization has never been officially noticed in Thailand. Thus, this study aimed to provide molecular epidemiology and characterization of the FCV circulating in Thai cats during 2016-2021. Moreover, the high-resolution melting analysis (HRM) is utilized for …
Developing A Detection Method For Rabies Virus Neutralizing Antibodies Using Pseudotype Technique, Nichapat Rojjananavin
Developing A Detection Method For Rabies Virus Neutralizing Antibodies Using Pseudotype Technique, Nichapat Rojjananavin
Chulalongkorn University Theses and Dissertations (Chula ETD)
Rabies is a neuro-fatal disease, causing by rabies virus (RABV) infection. Two serological tests, recommended by the World Health Organization and the World Organization for Animal Health, namely the rapid fluorescent focus inhibition test (RFFIT) and the fluorescent antibody virus neutralization test (FAVN) are considered gold standard. However, as both the RFFIT and FAVN require the use of live viruses, they raise biosafety concerns. Moreover, the immunostaining step in both methods is costly and time-consuming. In this study, RABV-pseudotype was developed and used in a RVNA detection method. The RABV-pseudotype based on lentivirus gave higher titer than the vesicular stomatitis …
Roles Of Balb/C Mice And Aedes Mosquitoes In The Transmission Of Duck Tembusu Virus, Nichapat Yurayart
Roles Of Balb/C Mice And Aedes Mosquitoes In The Transmission Of Duck Tembusu Virus, Nichapat Yurayart
Chulalongkorn University Theses and Dissertations (Chula ETD)
Duck Tembusu virus (DTMUV) is an emerging flavivirus that causes severe nervous and systemic diseases in avian hosts. The virus has been classified into three clusters, and the predominant cluster in Thailand is cluster 2.1. The pathogenesis of the virus has been extensively studied in avian hosts but not in mammalian hosts. Therefore, the first objective of this dissertation was to investigate the viral pathogenesis in mammalian hosts. Six-week-old BALB/c mice were intracerebrally and subcutaneously inoculated with Thai DTMUV to examine clinical signs, pathological change, viral load, and virus distribution. Results demonstrated that Thai DTMUV caused an acute severe disease, …
A Serological And Molecular Survey Of Sars-Cov-2 Infection In Domestic Dogs And Cats In Bangkok And Vicinity Thailand, Kitikhun Udom
A Serological And Molecular Survey Of Sars-Cov-2 Infection In Domestic Dogs And Cats In Bangkok And Vicinity Thailand, Kitikhun Udom
Chulalongkorn University Theses and Dissertations (Chula ETD)
The COVID-19 pandemic caused by SARS-CoV-2 has significant impact to human health worldwide. As of June 2022, over 500 million human cases with 6 million deaths have been reported. Despite SARS-CoV-2 infection in human, SARS-CoV-2 infections in domestic animals have also been reported due to spillover of the viruses from human-animals interface. The aim of this study was to conduct serological and molecular detection of SARS-CoV-2 in dogs and cats in Bangkok and vicinity in Thailand during the pandemic outbreaks. A large-scale SARS-CoV-2 survey in domestic animals which a total of 4,696 serum samples (2,960 of dogs, 1,736 of cats) …
Detection Of Antimicrobial Resistance In Escherichia Coli And Salmonella Spp. Originated From Cultivated Oysters And Estuarine Waters, Mullika Kuldee
Detection Of Antimicrobial Resistance In Escherichia Coli And Salmonella Spp. Originated From Cultivated Oysters And Estuarine Waters, Mullika Kuldee
Chulalongkorn University Theses and Dissertations (Chula ETD)
The raising and spreading antimicrobial resistance (AMR) bacteria in humans, animals, and environment is a serious global public health issue. Improper use of antimicrobial agents can promote resistant bacteria, and as a result, they can circulate in the environment. Contamination of AMR in the environment can increase the risk of AMR distribution in humans, animals, and the environment. Monitoring and surveillance of AMR in the environmental sector are limited compared to animal and human sectors. The objectives of this study were to determine phenotype and genotype of AMR and extended-spectrum beta-lactamase (ESBL) production in Escherichia coli and Salmonella isolated from …
Study Of Aerotolerant Campylobacter Jejuni In Broiler Production Process, Nichanan Jarusirivait
Study Of Aerotolerant Campylobacter Jejuni In Broiler Production Process, Nichanan Jarusirivait
Chulalongkorn University Theses and Dissertations (Chula ETD)
Campylobacter jejuni is the leading cause of human gastroenteritis worldwide. Although they are microaerophile and sensitive to oxygen, aerotolerant C. jejuni has been reported in many countries. Currently, limited information on aerotolerant C. jejuni in Thailand has been reported. Therefore, the objectives of this study were 1) to examine the occurrence of aerotolerant C. jejuni in farms, slaughterhouses and retail markets and compare the level of aerotolerant strain between different sample types at the farm (i.e., cloacal swabs VS manures) and slaughterhouse level (i.e., cecal contents VS carcass rinses) and 2) to identify common genotypes of aerotolerant and aerosensitive C. …
Knowledge, Attitude And Practice Associated With Brucellosis In Occupational Risk Groups In China, Quangang Xu
Knowledge, Attitude And Practice Associated With Brucellosis In Occupational Risk Groups In China, Quangang Xu
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study aimed to analyze the situation of knowledge, attitude, and practice (KAP) of sheep and goat farmers and community animal health staff towards the prevention and control of brucellosis. A total of 1,067 sheep and goat farmers and 401 community animal health staff from seven provinces in China were participated in this study from 2017 to 2018. Two structured questionnaire were used to examine demographic characteristics and KAP related to brucellosis. Descriptive statistics were used for demographic characteristics and KAP. Mann-Whitney U test was used to analyze the potential risk factors associated with KAP among participants. The overall awareness …
Selection Of Candidate Probiotic Bacteria From Chickens With Antagonism Against Campylobacter, Sirawich Danwanichwong
Selection Of Candidate Probiotic Bacteria From Chickens With Antagonism Against Campylobacter, Sirawich Danwanichwong
Chulalongkorn University Theses and Dissertations (Chula ETD)
Campylobacter is one of the most common causes of bacterial foodborne disease in humans worldwide. The effect of probiotics on Campylobacter control in poultry is inconsistent or rarely observed. For this reason, research on probiotics for Campylobacter control in poultry is required. Therefore, the objective of this study was to identify lactobacilli, Bacillus or Enterococcus strains isolated from Campylobacter-negative chickens which have the ability to inhibit the growth of Campylobacter in vitro and demonstrate favorable probiotic characteristics. A total of 602 bacterial isolates from Campylobacter-negative broiler chickens were assessed for their probiotic properties including Campylobacter inhibiting activity test, hemolytic activity …
In Vitro Inhibitory Effect Of Lactic Acid Bacteria And Their Supernatants On Flavobacterium Columnare Biofilm, Farras Daffa Imtiyaz
In Vitro Inhibitory Effect Of Lactic Acid Bacteria And Their Supernatants On Flavobacterium Columnare Biofilm, Farras Daffa Imtiyaz
Chulalongkorn University Theses and Dissertations (Chula ETD)
Flavobacterium columnare is an opportunistic bacterium causing columnaris disease to more than 37 fish species. It is believed that the bacteria form biofilm on the fish skin/surfaces before the bacteria in the biofilm produce and release enzymes that degrade connective and other tissues resulting in lesions on the infected fish. Treatments to inhibit the bacterial biofilm without interfering with its planktonic cell growth can be an alternative method to control columnaris disease. This study aimed to evaluate the efficacy of lactic acid bacteria (LAB) isolated from white leg shrimp gut (Penaeus vannamei) and the root of Jerusalem artichoke (Helianthus tuberosus) …
Prevalence And Molecular Characteristics Of Antimicrobial Resistance Of Aeromonas Hydrophila, Salmonella Spp., Vibrio Cholerae, Fecal Coliform, And Escherichia Coli In Hybrid Red Tilapia And Cultured Water, Varangkana Thaotumpitak
Prevalence And Molecular Characteristics Of Antimicrobial Resistance Of Aeromonas Hydrophila, Salmonella Spp., Vibrio Cholerae, Fecal Coliform, And Escherichia Coli In Hybrid Red Tilapia And Cultured Water, Varangkana Thaotumpitak
Chulalongkorn University Theses and Dissertations (Chula ETD)
Foodborne pathogens and antimicrobial resistant bacteria in tilapia and cultivation water has been emerged as a public health threat. This study aimed to determine the prevalence of indicator and pathogenic bacteria in hybrid red tilapia (Oreochromis spp.) and their cultivation water, and to characterize phenotypic and genotypic AMR, virulence genes, and extended-spectrum beta-lactamase (ESBL) production of Escherichia coli, Aeromonas hydrophila, Salmonella spp., and Vibrio cholerae. A total of 120 tilapia, which were comprised of carcass rinse (n=120), muscle (n=120), intestine (n=120), liver and kidney (n=120), and cultivation water (n=120) were collected from tilapia farms in Kanchanaburi province, Thailand during October …
Genetic Characterizations, Virulence, Antimicrobial Resistances And Resistome Analysis Of Vibrio Spp. Isolated From Farmed Asian Sea Bass (Lates Calcarifer) In Thailand, Hartanto Mulyo Raharjo
Genetic Characterizations, Virulence, Antimicrobial Resistances And Resistome Analysis Of Vibrio Spp. Isolated From Farmed Asian Sea Bass (Lates Calcarifer) In Thailand, Hartanto Mulyo Raharjo
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study describes the etiological agent of Vibriosis along with its distribution and antimicrobial resistance profiles among farmed Asian sea bass (Lates calcarifer) in Thailand. The study isolated 283 Vibrionaceae from 15 Asian sea bass farms located around the provinces of the Andaman Sea and Gulf of Thailand coasts to uncover the distribution and antimicrobial resistance profiles. Bacterial identification based on a combination of the biochemical characteristics, Matrix-assisted laser desorption/ ionization-time of flight (MALDI-TOF) mass spectrometry (MS) analysis, and the species-specific PCR demonstrated the predominant Vibrionaceae were Vibrio harveyi (n = 56), Photobacterium damselae (n = 35), and V. vulnificus …
Identification, Characterization And Pathogenicity Of Aeromonas Schubertii Isolated From Diseased Striped Snakehead Fish (Channa Striata), Hendri Budiyansah
Identification, Characterization And Pathogenicity Of Aeromonas Schubertii Isolated From Diseased Striped Snakehead Fish (Channa Striata), Hendri Budiyansah
Chulalongkorn University Theses and Dissertations (Chula ETD)
Striped snakehead fish (Channa striata) is one of the popular cultivated fish in Thailand. However, it is inevitable to be susceptible to abundant pathogens, especially Aeromonas schubertii. In July 2020, an unknown outbreak was occurred on striped snakehead fish nursery farm in Nakhon Pathom province, Thailand. Suspected six isolates were A. schubertii yielded from the fish as the main causative agent. This research aimed to characterize and examine pathogenicity of A. schubertii isolated from diseased striped snakehead fish. Characterization was performed based on combination of biochemical assay, PCR and DNA sequencing (based on 16S rRNA and gyrB), and MALDI-TOF MS. …