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Pm10 And Pm2.5 Concentrations In Bangkok Over 10 Years And Implications For Air Quality, Tin Thongthammachart
Pm10 And Pm2.5 Concentrations In Bangkok Over 10 Years And Implications For Air Quality, Tin Thongthammachart
Chulalongkorn University Theses and Dissertations (Chula ETD)
Atmospheric particulate matter particles with a diameter less than 10 micron (PM10) and less than 2.5 micron (PM2.5) have been adverse human health effect. Ambient air pollution data in Central Business District (CBD) of Bangkok monitored by Pollution Control Department and Bangkok Metropolitan Administration were collected over ten years in Bangkok from 2008 to 2017. Trend of the particulate matter concentrations data were investigated over ten year for implications of activities related to air pollution. Daily average air pollution data between year 2015 and year 2017 were used as the dependent variables to develop mathematic models with multiple linear regression …
Explaining Barriers And Opportunities For Recycled Pet For Food Packaging In Thailand Through The Lenses Of Organizational Environment Theory, Natawadee Sirithorn
Explaining Barriers And Opportunities For Recycled Pet For Food Packaging In Thailand Through The Lenses Of Organizational Environment Theory, Natawadee Sirithorn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Currently, some plastic-related companies propose a solution of recycled plastic (rPET) for food packaging as a solution for the plastic problem in Thailand. Therefore, the objective of the thesis is to study business behavior in order to understand the rationale of why some company needs to use rPET for food packaging. This study combined two theories which are the organizational environment theory and the institutional theory of CSR to analyze the effect of the internal and the external environment that influence companies to support rPET food packaging. The finding indicates that companies' mission creates an influence on companies to promote …
Chin Diaspora And Their Social Networks In Thailand : Implications For Development In Myanmar, Pau Sian Lian
Chin Diaspora And Their Social Networks In Thailand : Implications For Development In Myanmar, Pau Sian Lian
Chulalongkorn University Theses and Dissertations (Chula ETD)
Due to socioeconomic and political reasons, Chin ethnic people from the western part of Myanmar have been migrating to inner part of the country and abroad. Economic growth and requirement of low skill labor in Thailand since the 1980s have been the pull factors for low skill migrants from its neighbors, including Myanmar. Chin people came to Thailand not only for economic opportunities but also for onward migration. The purpose of this research is to explore the social networks of Chin diaspora in Thailand and their implication to the economic and political development of their home community in Myanmar. With …
Women Political Participation In MyanmarS House Of Representatives, Thu Thu Swe
Women Political Participation In MyanmarS House Of Representatives, Thu Thu Swe
Chulalongkorn University Theses and Dissertations (Chula ETD)
The thesis mainly discusses about main obstacles and challenges for women to participate in political activities in Myanmar including economic factor, social factor, political factor, and the ways how women are empowered to participate in political activities in Myanmar by using both primary and secondary data. The primary concept for this study is based on women empowerment processes which are included four different pathways in which women are changed –material (economy), perceptual (knowledge and skill), cognitive (self-confident and self-esteemed) and relational (bargaining power). Moreover, the thesis analyses actor's roles in these four pathways. The thesis found out external factors namely …
Ulaanbaatar's Ger District Residents: An Analysis Of Development Challenges And Structural Violence, Timothy Shaun Jenkins
Ulaanbaatar's Ger District Residents: An Analysis Of Development Challenges And Structural Violence, Timothy Shaun Jenkins
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study investigates and researches the impact of the Government's policy of putting the 'economy first' by analyzing the situation through the lens of Johan Galtung's concept of Structural Violence. The research answers the question: How does structural violence occur in the ger districts of Ulaanbaatar under the current development challenges? In the 1990's, after the fall of communism, the IMF and the World Bank, along with some leading political figures within the Government of Mongolia, pushed forward with their plans to bring the free market to Mongolia. The World Bank and the IMF introduced the shock-therapy approach with the …
Key Success Factors Of Starbucks Coffee In South Korea, Chandhit Sawangnate
Key Success Factors Of Starbucks Coffee In South Korea, Chandhit Sawangnate
Chulalongkorn University Theses and Dissertations (Chula ETD)
Food and beverage is one of the industries that have been contributing economic growth toward South Korea economy for a decades; however, coffee market due to a relatively high competition and fierceness, coffee war, between international brands and local brands. This paper is trying to find the key success factors of Starbucks through various dimensions in South Korea market. This study is in order to find competitive advantages of Starbucks internationally and domestically. Observation is also held to find an insight data. The outcome shows that Korean coffee market has strength in it character conditions. The coffee quality and coffee …
Juche Realist Music : The Politicization Of Music In North Korea, Jungmin Heo
Juche Realist Music : The Politicization Of Music In North Korea, Jungmin Heo
Chulalongkorn University Theses and Dissertations (Chula ETD)
In North Korea, music and songs have extensively been used as an effective political tool of state propaganda. Unlike previous research which overlooks the contents of the songs, this thesis examines how their lyrics reflect political ideologies and propaganda operation of North Korean regimes. Their lyrics are analyzed in light of the historical context they were written in and widely perceived. It aims at contributing to the knowledge of North Korean music and its relationship with the politics of the country. The study analyzes the lyrics of 100 North Korean songs from 4 different sources using qualitative contents analysis. The …
A Study Of Social Change And Dining Culture In Korean Society : The Case Of Honbap (혼밥), Nutnicha Somporn
A Study Of Social Change And Dining Culture In Korean Society : The Case Of Honbap (혼밥), Nutnicha Somporn
Chulalongkorn University Theses and Dissertations (Chula ETD)
The purpose of this study is to understand the social change and dining culture in Korean society by emphasizing in Honbap (혼밥), which means eating alone. In Asian countries as Korean society is a collectivism society which people are strong in-groups for a long time, unlike the Western countries where people are in individualism society. The influence of collectivistic values includes the dining culture in Korean society as eating out. Normally, Korean people usually prefer to eat with friends, family members, colleagues rather than eating alone. Eating alone in public looks strange like an outcast, it is hard to find …
Korean Brand Ambassadors And Nationalism, Pacharawan Pathmanand
Korean Brand Ambassadors And Nationalism, Pacharawan Pathmanand
Chulalongkorn University Theses and Dissertations (Chula ETD)
The purpose of this study is to examine the expression of Nationalism that it is the main reason brands chosen the Korean Brand Ambassadors. The result of the study on the topic of Korean Brand Ambassadors and Korean nationalism explained that Korean domestic market needs a nationalist as a Brand Ambassadors to sell cultural products such as SoJu (Korean Beverage). Furthermore, in case of selling products in International market, being a nationalist is not the key for brands to have chosen the Brand Ambassador. However, if the Brand Ambassadors chose to represent himself or herself as a nationalist, they can …
Influence Of South Korea's Soft Power On The Extension Of Korean Language In Thailand, Kunathai Onnom
Influence Of South Korea's Soft Power On The Extension Of Korean Language In Thailand, Kunathai Onnom
Chulalongkorn University Theses and Dissertations (Chula ETD)
The research named "Influence of South Korea's Soft Power on the Extension of Korean Language in Thailand", has aimed to understand and explain the background of South Korea's soft power in a globalization context. The research will emphasize on the extension of Korean soft power to Thailand by using the Korean language as a key instrument. About the methodology, this research firstly collected the document information from reviewing previous researches, books, articles and other online sources. As being the qualitative research, the in-depth interview has proceeded discreetly with 25 key informants from many related-fields such as undergraduate students, employees, businessman …
B-Cell Activating Factor As An Immunological Marker Of Disease Outcome And Treatment Response In Patients With Chronic Hepatitis B Virus Infection, Apichaya Khlaiphuengsin
B-Cell Activating Factor As An Immunological Marker Of Disease Outcome And Treatment Response In Patients With Chronic Hepatitis B Virus Infection, Apichaya Khlaiphuengsin
Chulalongkorn University Theses and Dissertations (Chula ETD)
B-cell activating factor (BAFF), an important cytokine for B lymphocyte activation that implicated in the pathogenesis and disease progression chronic hepatitis B (CHB) patients. This study aimed at evaluating clinical correlation and prognostic role of plasma BAFF, BAFF receptor and related polymorphisms in patients with CHB undergoing pegylated interferon (peg-IFN) treatment and HBV-related hepatocellular carcinoma (HCC). This study shown that BAFF levels were elevated during treatment but decreased to pre-treatment levels after peg-IFN cessation in HBeAg-positive CHB patients. Patients with HCC had significantly higher BAFF levels compared with the non-HCC group and healthy controls. Moreover, the frequency of rs9514828 CT+TT …
Dosimetric Comparison Between Using Daily Cone Beam Ct And Planning Ct In Volumetric Modulated Arc Therapy Technique For Prostate Cancer Therapy, Julaluck Chanayota
Dosimetric Comparison Between Using Daily Cone Beam Ct And Planning Ct In Volumetric Modulated Arc Therapy Technique For Prostate Cancer Therapy, Julaluck Chanayota
Chulalongkorn University Theses and Dissertations (Chula ETD)
The variations of shape and size of organs inside, especially bladder and rectum, in prostate cancer patient are mainly factors of external beam radiation therapy that may impact to disease control and normal tissue toxicity. The purpose of this study was to investigate the dosimetric comparison between using daily CBCT and planning CT in Volumetric modulated arc therapy (VMAT) technique for prostate cancer therapy. The HU and electron density between CBCT and planning CT were verified by using Catphan® 600 phantom. Treatment planning system was verified by dose distribution comparison between plans on CBCT and planning CT images of Anthropomorphic …
Characterization Of Leptospiral Extracellular Vesicles In Stress Conditions, Eakalak Phanchamnan
Characterization Of Leptospiral Extracellular Vesicles In Stress Conditions, Eakalak Phanchamnan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Pathogenic Leptospira spp. is a causative agent of leptospirosis, a worldwide zoonosis with public health concern especially in the urban slum of metropolis and rural areas in tropical and subtropical countries. The pathogenesis of leptospirosis remains elusive. Extracellular vesicles (ECVs), which pinch off from the bacterial membranes, simultaneously harbor multiple active molecules that may serve as a secretion system, communication tool, and vaccine candidates. Recently, chemically induced leptospiral ECVs were studied and used as vaccine candidates. However, the naturally produced leptospiral ECVs has not been characterized. This study aimed to identify proteins in leptospiral ECVs produced under stress conditions including …
Mechanisms Of Ceftriaxone Resistance In Neisseria Gonorrhoeae Isolated From Thai Patients, Naris Kueakulpattana
Mechanisms Of Ceftriaxone Resistance In Neisseria Gonorrhoeae Isolated From Thai Patients, Naris Kueakulpattana
Chulalongkorn University Theses and Dissertations (Chula ETD)
N. gonorrhoeae is the causative agent of gonorrhea, which is one of the most important sexually transmitted disease. The multidrug resistance in N. gonorrhoeae has been increasingly reported worldwide. The objectives of this study were to investigate the prevalence and the mechanisms of ceftriaxone resistance in N. gonorrhoeae Thai isolates, and to investigate the synergistic activities of antibiotic combinations against N. gonorrhoeae isolates with reduced susceptibility or resistance to ceftriaxone. A total of 134 N. gonorrhoeae isolates were included in this study. The resistance rates of ciprofloxacin, tetracycline, penicillin G, gentamicin, azithromycin, ertapenem, fosfomycin, cefixime, and ceftriaxone were 90.30%, 82.09%, …
The Role Of Histone Methylation Of H3k4 In Polarization Of Macrophages Stimulated By Immune Complex And Lipopolysaccharide And Its Therapeutic Potential In Sepsis, Vichaya Ruenjaiman
The Role Of Histone Methylation Of H3k4 In Polarization Of Macrophages Stimulated By Immune Complex And Lipopolysaccharide And Its Therapeutic Potential In Sepsis, Vichaya Ruenjaiman
Chulalongkorn University Theses and Dissertations (Chula ETD)
Macrophage plasticity is a process that allows macrophages to switch between two opposing phenotypes based on differential stimuli. Functional plasticity of macrophages contributes to disease pathogenesis such as cancer, metabolic diseases, autoimmune diseases and systemic infections. Epigenetics plays an important role in regulating this process. Macrophages stimulated with lipopolysaccharide (LPS) (M(LPS)) produce high level of pro-inflammatory cytokines such as IL-12, TNFα and IL-6 and low level of anti-inflammatory cytokine IL-10, while macrophages stimulated with LPS in the presence of immune complex (IC) (M(IC)) produce high level of IL-10 and low level of IL-12. In this study, we investigated the plasticity …
Comprehensive Proteomics Identification Of Ifn-Λ3-Regulated Antiviral Proteins In Hbv-Transfected Cells, Jiradej Makjaroen
Comprehensive Proteomics Identification Of Ifn-Λ3-Regulated Antiviral Proteins In Hbv-Transfected Cells, Jiradej Makjaroen
Chulalongkorn University Theses and Dissertations (Chula ETD)
Interferon (IFN)-λ is a relatively unexplored, yet promising anti-viral agent. IFN-λ has recently been tested in clinical trials of chronic hepatitis B, with the advantage that side effects may be limited compared with IFN-α, as IFN-λ receptors are found only in epithelial cells. To date, IFN-λ downstream signaling pathway remains largely unelucidated, particularly via proteomics methods. Here, we report that IFN-λ3 inhibits HBV replication in HepG2.2.15 cells, reducing levels of both HBV transcripts and intracellular HBV DNA. Quantitative proteomic analysis of HBV-transfected cells was performed following 24-hour IFN-λ3 treatment, with parallel IFN-α2a and PBS treatments for comparison using a dimethyl …
The Severity Of Cryptococcus Neoformans Infection In Fc Gamma Receptor Iib Deficient Mice, Saowapha Surawut
The Severity Of Cryptococcus Neoformans Infection In Fc Gamma Receptor Iib Deficient Mice, Saowapha Surawut
Chulalongkorn University Theses and Dissertations (Chula ETD)
Cryptococcus neoformans, an encapsulated yeast commonly infecting the central nervous system, refers to as cryptococcal meningitis or cryptococcosis is commonly found in Thailand. C. neoformans is able to replicate, survive inside host macrophages, evade from the cells and use macrophages as a vehicle to disseminate to the target organs, a mechanism known as Trojan horse. Therefore, the containment of C. neoformans in phagocytic cell is important for host protective immunity. Cryptococcosis is common in immunocompromised host such as in patients with low CD4+ T helper cells in HIV-infection and patients taking immunosuppressive drugs. However, the incidence of cryptococcosis in healthy …
Antilithogenic Efficacy Of An Innovative Beverage Hydrozitla: In Vitro And In Vivo Studies, Nalinthip Lordumrongkiat
Antilithogenic Efficacy Of An Innovative Beverage Hydrozitla: In Vitro And In Vivo Studies, Nalinthip Lordumrongkiat
Chulalongkorn University Theses and Dissertations (Chula ETD)
Urinary stone disease is a common urologic disease worldwide, and it is highly recurrent. Calcium oxalate (CaOx) stone is the most common type of urinary stones. The main causes of urinary stone formation include inadequate water intake, low urinary citrate excretion and increased oxidative stress. At the present day, potassium citrate is a drug of choice for preventing stone formation and recurrence. We developed a new regimen for preventing urinary stone formation, called HydroZitLa. It was in a form of concentrate in pouch. For consumption, water was added up to 500 mL and shake well before drink. Therefore, drinking of …
Phosphoproteomic Analysis Of Fc Gamma Receptor Iib Deficient Macrophages In Enhancing The Severity Of Endotoxin Tolerance, Thunnicha Ondee
Phosphoproteomic Analysis Of Fc Gamma Receptor Iib Deficient Macrophages In Enhancing The Severity Of Endotoxin Tolerance, Thunnicha Ondee
Chulalongkorn University Theses and Dissertations (Chula ETD)
Sepsis is a severe response to systemic infection and one of the leading causes of death in patients world-wide. Bacterial endotoxin (lipopolysaccharide; LPS), is a potent inducer of inflammation that has been associated with the pathophysiology of sepsis. The repeated LPS exposure can induce a suppressive effect as refer to endotoxin tolerance. Fc gamma receptor IIb (CD32b), the only inhibitory receptor among FcGR family, associates with systemic lupus erythematosus (FcGRIIb defunctioning polymorphisms) which are commonly found in Asian populations. Because of an inhibitory nature of the signaling, endotoxin tolerance in lupus with FcGRIIb deficient (FcGRIIb-/-) is interesting and might be …
Anticancer Activity Of Plumbagin On Stem-Like Characteristics, Tumor Angiogenesis And Metastatic Potential In Endocrine Resistant Breast Cancer, Nithidol Sakunrangsit
Anticancer Activity Of Plumbagin On Stem-Like Characteristics, Tumor Angiogenesis And Metastatic Potential In Endocrine Resistant Breast Cancer, Nithidol Sakunrangsit
Chulalongkorn University Theses and Dissertations (Chula ETD)
Plumbagin (PLB), a naphthoquinone compound and vitamin K3 derivative, was shown its potent cytotoxicity and anti-invasion in anti-hormonal resistant cells through the inhibition of Snail-induced epithelial mesenchymal transition (EMT). Overexpression of Snail leads to decrease E-cadherin and increase of beta-catenin, resulting in the activation of Wnt pathway that increases cancer stem-like characteristics in these resistant cells. This study was aimed to investigate the inhibitory effects of PLB on cancer stem-like cells (CSLCs), angiogenesis and Wnt signaling-mediated cell proliferation and invasion. In addition, our study also focused on the anticancer activity of PLB in anti-hormonal resistant breast cancer in vivo. Both …
Metabolic Engineering Of Synechococcus Elongatus Pcc 7942 For Mycosporine-2-Glycine Production Under Salt Stress Condition, Panwad Pingkhanont
Metabolic Engineering Of Synechococcus Elongatus Pcc 7942 For Mycosporine-2-Glycine Production Under Salt Stress Condition, Panwad Pingkhanont
Chulalongkorn University Theses and Dissertations (Chula ETD)
ไมโครสปอรีน-ไลก์ อะมิโน แอซิด (MAAs) เป็นกลุ่มของสารเมแทบอไลต์ทุติยภูมิ สังเคราะห์โดยจุลินทรีย์และสาหร่ายหลายชนิด สารกลุ่มนี้มีหน้าที่สำคัญในการคัดกรองรังสียูวี และยังมีหน้าที่อื่นๆ ได้แก่ การต้านอนุมูลอิสระ ปกป้องเซลล์จากภาวะเครียด และควบคุมการออสโมซิส โดยไมโครสปอรีน-2-ไกลซีน (M2G) เป็นหนึ่งในสารกลุ่ม MAAs ที่มีความสามารถในการต้านอนุมูลอิสระมากกว่าสารอื่นๆ ในกลุ่มเดียวกัน ดังนั้นจึงเป็นที่สนใจที่จะเพิ่มการผลิต M2G เพื่อนำไปประยุกต์ใช้ในอุตสาหกรรมความงาม และเวชสำอาง ในการศึกษานี้ประสบความสำเร็จในการแสดงออกของยีนในชีวสังเคราะห์ M2G (Ap3858-3855) จาก Aphanothece halophytica ในไซยาโนแบคทีเรียน้ำจืด Synechococcus elongatus PCC 7942 จากการวิเคราะห์การถอดรหัสของยีน Ap3858-3855 พบว่า ยีนทั้ง 4 ยีนนี้เป็น monocistronic mRNA heterologous expression ของยีน Ap3858-3855 ใน S. elongatus พบว่าทุกยีนมีการแสดงออกมากขึ้นภาวะเครียดจากเกลือ NaCl ยีน Ap3857 แสดงออกเพิ่มมากที่สุด 2.39 ± 0.25 เท่า และภายใต้ภาวะเครียดจากเกลือ KCl ยีน Ap3856 แสดงออกเพิ่มมากที่สุด 3.70 ± 0.35 เท่า ระดับการแสดงออกของยีนที่เกี่ยวข้องกับภาวะเครียดออกซิเดชั่น (sodB, cat และ tpxA) ในเซลล์แสดงออก พบว่าภายใต้ภาวะเครียดจากเกลือ NaCl มีเพียงยีน tpxA แสดงออกมากขึ้น 4.58 ± 0.58 เท่า ขณะที่ภาวะเครียดจากเกลือ KCl กระตุ้นการแสดงออกของ sodB และ tpxA 4.09 ± 0.86 และ 11.81 ± 1.02 เท่า ตามลำดับ ส่วนการแสดงออกของยีนที่เกี่ยวข้องกับสารออสโมไลท์ ได้แก่ Synpcc7942_0808 และ …
Production Of Monoclonal Antibodies Against Interferon Gamma Of Asian Elephant Elephas Maximus For Tuberculosis Diagnosis In Elephants By Interferon Gamma Release Assay, Songkiat Songthammanuphap
Production Of Monoclonal Antibodies Against Interferon Gamma Of Asian Elephant Elephas Maximus For Tuberculosis Diagnosis In Elephants By Interferon Gamma Release Assay, Songkiat Songthammanuphap
Chulalongkorn University Theses and Dissertations (Chula ETD)
Tuberculosis is a zoonotic disease that can be transmitted from infected animals to humans. Wild animals such as elephants and non-human primate have been reported to be infected by M. tuberculosis (MTB) complex, which can cause tuberculosis in animals as well. The common TB diagnostic approaches in human such as chest X-ray and tuberculin skin test are not practical in the elephants. Moreover, the gold standard of the bacteria culture from trunk wash has low sensitivity, is time-consuming and can only detect tuberculosis in the active stage. Therefore, an accurate diagnosis covering all phases of the MTB infection is in …
Comparison Of The Implant Deviation Between Implants Placed Using Static And Dynamic Computer Assisted Surgery Methods, Dechawat Kaewsiri
Comparison Of The Implant Deviation Between Implants Placed Using Static And Dynamic Computer Assisted Surgery Methods, Dechawat Kaewsiri
Chulalongkorn University Theses and Dissertations (Chula ETD)
Objectives: The aim of this study was to compare the accuracy of implant placement in terms of deviations related to the virtual plan between static and dynamic computer assisted implant surgery (CAIS) systems in single tooth space. Materials & Methods: 60 single implants were randomly placed using two difference CAIS systems by one surgeon. Preoperative CBCT transferred to implant planning software were used to plan the virtual implant position. Implants were placed using either stereolithographic guide template for static CAIS group (n = 30) or implant navigation system for dynamic CAIS group (n = 30). Postoperative CBCT were taken to …
Perceptions, Expectations, And Satisfaction Of Patients Undergoing Dental Implant Therapy In The Faculty Of Dentistry, Chulalongkorn University, Khunsiri Sermsiripoca
Perceptions, Expectations, And Satisfaction Of Patients Undergoing Dental Implant Therapy In The Faculty Of Dentistry, Chulalongkorn University, Khunsiri Sermsiripoca
Chulalongkorn University Theses and Dissertations (Chula ETD)
The aims of this study were to evaluate patient's perception before and after receiving dental implant therapy and to investigate patient's perception, expectation, and satisfaction of dental implant treated by postgraduate dental students and faculty members. This study was designed with a quantitative cross-sectional technique. The data were collected by 3 questionnaires, from patients who intended to receive dental implant treatment during September 2017 to February 2019. Two hundred and fifty participants participated in this study. Most of them were female, aged 55-64 years, graduated bachelor's degree, and facial and teeth appearance did not affect their career. The proportion of …
Comparative Study Of The Accuracy Of Single Tooth Implants Placed Between Static And Mental Computer Assisted Surgery, Palita Smitkarn
Comparative Study Of The Accuracy Of Single Tooth Implants Placed Between Static And Mental Computer Assisted Surgery, Palita Smitkarn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Objective: This randomized controlled clinical trial aimed to compared the accuracy of implant position between static and mental Computer Assisted Implant Surgery (CAIS) in single tooth gap. Materials and methods: 52 patients who received 60 implants in single tooth gap, randomized equally into static or mental CAIS. In static CAIS group, data from CBCT scan and data from intraoral or model scan were utilised for the three dimensional virtual planning implant positioning and desiring of a three dimensional surgical guide in implant planning software. Implant bed preparation and implant insertion were done through the three dimensional surgical guide. Implants in …
Comparison Of Single-Dose And Multi-Dose Antibiotic Prophylaxis In Orthognathic Surgery: A Retrospective Cohort Study, Teeraphat Pochana
Comparison Of Single-Dose And Multi-Dose Antibiotic Prophylaxis In Orthognathic Surgery: A Retrospective Cohort Study, Teeraphat Pochana
Chulalongkorn University Theses and Dissertations (Chula ETD)
Objective: (1) to compare the prophylactic effect of a single versus a multiple dose antibiotic regimens and (2) to determine factors related to surgical site infection in orthognathic surgery. Materials and methods: Medical records of patients underwent orthognathic surgery in the Faculty of Dentistry, Chulalongkorn University between 2014 and 2016 were extracted for medical data including demographic data, American Society of Anesthesiologists (ASA)-classified past medical history, orthognathic surgical procedures and complications, prophylactic antibiotic regimen, and surgical site infection. The records also contained 30-day follow-up information, according to the Centers for Disease Control and Prevention (CDC) diagnostic criteria for surgical site …
Pd-1 Expression On Immune Cells In Sepsis Mouse Model And The Susceptibility To Secondary Fungal Infection, Chau Tran Bao Vu
Pd-1 Expression On Immune Cells In Sepsis Mouse Model And The Susceptibility To Secondary Fungal Infection, Chau Tran Bao Vu
Chulalongkorn University Theses and Dissertations (Chula ETD)
Objectives: This study aimed to i) determine the kinetic changes of immune cell phenotypes, including an exhaustion marker PD-1, in spleens of murine sepsis ii) investigate the susceptibility against secondary fungal infection after sepsis, and iii) investigate the efficacy of an anti-PD-1 treatment in post-sepsis fungal infection. Methods: Cecal ligation and puncture (CLP) was used as a sepsis model and splenocytes post-CLP were assessed by flow cytometry. In addition, secondary post sepsis systemic fungal infections by Candida albicans or Aspergillus fumigatus administration at 5-day post-CLP were performed. Moreover, secondary aspergillosis was treated with Amphotericin B with or without anti-PD-1 to …
Tlr3 Signaling Modulates Immunomodulatory Property Of Human Periodontal Ligament Stem Cells., Daneeya Chaikiawkeaw
Tlr3 Signaling Modulates Immunomodulatory Property Of Human Periodontal Ligament Stem Cells., Daneeya Chaikiawkeaw
Chulalongkorn University Theses and Dissertations (Chula ETD)
Toll like receptor 3 (TLR3) is a member of TLR family functions to recognizes double-stranded RNA (dsRNA) produced by positive-strand RNA viruses and DNA virusesand generate signaling that stimulate body immune system against virus infection. However, recent evidence suggests that TLR3 signaling may also play a role in initiating the immunosuppressive property of the cells. Study on skin regeneration has shown the anti-inflammatory responses of keratinocytes required for wound healing andthe increasing number of hair follicle formation after TLR3 signaling was activated by fragment of RNA released from damaged cells. Moreover, activation of TLR3 signaling have shown to elicit a …
Effect Of Cyclic Tensile Force On The Expression Of Bone Morphogenetic Protein 9 And Interleukin 6 In Human Periodontal Ligament Cells, Yanee Tantilertanant
Effect Of Cyclic Tensile Force On The Expression Of Bone Morphogenetic Protein 9 And Interleukin 6 In Human Periodontal Ligament Cells, Yanee Tantilertanant
Chulalongkorn University Theses and Dissertations (Chula ETD)
Periodontium is a specialized tissue laying between tooth and surrounding bone. It functions as force cushion. In particular stimulation including mechanical force, periodontal ligament (PDL) cells which are mechanosensitive cells have the ability to secrete specific cytokines and proteins. PDL cells also have the potential to differentiate into osteoblast-like cells or fibroblast-like cells. PDL cells perceive combination of force in oral cavity in which major component is cyclic tensile force (CTF). CTF play an essential role in modulating PDL cells to maintain both hard and soft tissue integrity. Here, we demonstrated that CTF was able to stimulate the expression of …
Preparation And Characterization Of Starch Films Reinforced With Citrate Cellulose Nanocrystals, Prapaporn Nakarat
Preparation And Characterization Of Starch Films Reinforced With Citrate Cellulose Nanocrystals, Prapaporn Nakarat
Chulalongkorn University Theses and Dissertations (Chula ETD)
Citrate-modified bacterial cellulose nanocrystals (citrate CNCs) were prepared by a green one-pot dual acid (citric and hydrochloric acids) method and used them to reinforce three types of starch films; corn, wheat and rice starch films. The average length and width of citrate CNCs were 583 and 46 nm, respectively. The degree of citrate substitution on CNCs was 0.075 and its crystallinity index was closely to the original bacterial cellulose. The effect of various amount of citrate CNCs (0-20%wt of starch) on film property was study. Three starch films showed the same trend of examination results. The film thickness of most …