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The Association Of Mirnas As Biomarkers For Severe Liver Dysfunction In Severe Dengue Infection, Napat Pas-Arj Jan 2024

The Association Of Mirnas As Biomarkers For Severe Liver Dysfunction In Severe Dengue Infection, Napat Pas-Arj

Chulalongkorn University Theses and Dissertations (Chula ETD)

Identification early biomarkers for severe liver dysfunction in severe dengue patients is essential. Currently, there is no any data on circulating miRNAs to predict this important complication, Therefore, this study aimed to explore the role of circulating miRNAs in severe liver dysfunction in dengue infection. On the initial day of admission, serum samples were gathered from patients with dengue infection. These patients were monitored for 14 days post-admission to ascertain their final diagnosis. Following the WHO 2009 criteria, participants were categorized into severe liver dysfunction and non-severe liver dysfunction group. To conduct a transcriptomic analysis of circulating miRNAs used the …


Gene Expression By Nanostring Rna Profiling Of Monocytic Myeloid-Derived Suppressor Cells In Knee Osteoarthritis, Varote Shotelersuk Jan 2024

Gene Expression By Nanostring Rna Profiling Of Monocytic Myeloid-Derived Suppressor Cells In Knee Osteoarthritis, Varote Shotelersuk

Chulalongkorn University Theses and Dissertations (Chula ETD)

Osteoarthritis (OA) is a widespread degenerative joint disease marked by cartilage destruction. This study investigates the role of monocytic myeloid-derived suppressor cells (M-MDSCs) in OA, focusing on their gene expression profiles and their relationship with body mass index (BMI) in knee OA patients. Previous research has shown a positive correlation between M-MDSCs and BMI in OA. We explored the role of M-MDSCs derived from the infrapatellar fat pad (IPFP) in OA patients.Using NanoString technology, we examined the transcriptional profile of M-MDSCs from the IPFP of knee OA patients undergoing total knee replacement surgery, categorized into different BMI groups. Flow cytometry …


Association Between Volunteering, Wellbeing, And Homo-Negativity: An Analysis Of World Values Survey, Amirhossein Khanehpaza Jan 2024

Association Between Volunteering, Wellbeing, And Homo-Negativity: An Analysis Of World Values Survey, Amirhossein Khanehpaza

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: Homonegativity adversely affects the health and well-being of homosexuals in society, making it vital to identify factors associated with it. This study investigates whether active membership in voluntary organizations correlates with homonegativity, examining how this varies by gender and age.Methods: Using the World Values Survey data (2017-2022) from 87,777 participants in 63 countries, we performed binary logistic regression to assess relationships between homonegativity and factors including socioeconomic status, demographics, and voluntary activity participation.Results: Our findings suggest that active membership in certain voluntary organizations correlates with homonegativity levels among both men and women across various age groups. Specifically, active participation …


Structural Analysis Of Thailand's Economy During The “Developmental Era” From 1957 To 1997 Using The Social Structure Of Accumulation Theory, Paworn Kiatyutthachart Jan 2024

Structural Analysis Of Thailand's Economy During The “Developmental Era” From 1957 To 1997 Using The Social Structure Of Accumulation Theory, Paworn Kiatyutthachart

Chulalongkorn University Theses and Dissertations (Chula ETD)

This thesis tried to describe the progress of growth and recession of the Thai economy during the “developmental era” of the 1950s to 2000s. The main objective of this thesis is to find Thailand’s Social Structure of Accumulation, using it to trace back to the “critical junctures” and then describe the trajectory of Thailand’s economic development. The Social Structure of Accumulation is obtained by calculating the rate of profit to identify “long waves” of changes in the rate of profit, and also through documentary research of both primary and secondary sources to find a “set of structures” related to the …


The Impact Of U.S. Monetary Policy Expectations On Emerging Market Sovereign Bonds, Qiaofang Chen Jan 2024

The Impact Of U.S. Monetary Policy Expectations On Emerging Market Sovereign Bonds, Qiaofang Chen

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study examines the spillover effects of U.S. monetary policy on sovereign bonds in emerging market economies (EMEs). It evaluates the influence of various phases of U.S. monetary policy, including quantitative easing (QE) and quantitative tightening (QT), on EME sovereign bond prices and yields. The analysis pays special attention to differences in the impacts on bonds denominated in local currencies versus U.S. dollars. The results indicate that U.S. monetary policy significantly affects the prices of both USD- and local currency-denominated bonds in EMEs, except during the pre-unconventional monetary policy period. The adverse effects of U.S. monetary policy adjustments, particularly during …


The Effects Of Ai On Export Cutoff For High-Tech Industries In China, Baobao Lou Jan 2024

The Effects Of Ai On Export Cutoff For High-Tech Industries In China, Baobao Lou

Chulalongkorn University Theses and Dissertations (Chula ETD)

Given the surge in Chinese high-tech exports from 2016 to 2021, this paper presents the first quantitative estimation of the export cutoff productivity for Chinese firms. It explores the impact of AI on export cutoff productivity at the firm level by applying text mining, the WLP method (2009), and the ROC method to 958 listed high-tech firms in China. The study finds that the export cutoff productivity threshold for Chinese high-tech industries significantly increased following the adoption of AI. This indicates that AI adoption raises the export cutoff. However, this paper also finds that AI’s adoption also improves the chance …


Development Of Titanate-Based High-Entropy Perovskite Oxides For High-Energy Density Capacitor, Ketkaeo Bunpang Jan 2024

Development Of Titanate-Based High-Entropy Perovskite Oxides For High-Energy Density Capacitor, Ketkaeo Bunpang

Chulalongkorn University Theses and Dissertations (Chula ETD)

The development of dielectric materials with suitable properties for high-energy density capacitors is essential for the advancement of future electronic technologies. This study focuses on the effects of substituting monovalent and trivalent ions at the A and B sites in high-entropy perovskite oxide structures based on titanates. (A'0.2A"0.2Ba0.2Ca0.2Sr0.2)(Ti1-xMex)O3 (A' = Na+, K+, A" = Bi3+, La3+, Me = Zr4+, (Mg1/3Nb2/3)4+, x = 0.00–0.2) compounds were synthesized using the solid-state reaction method. The results revealed that compounds containing Bi3+ exhibited a high dielectric constant (~3000), low dielectric loss (~0.1), and stable relaxor ferroelectric behavior. In contrast, compounds containing La3+ displayed linear …


Salt Tolerance In Rice ‘Jao Khao’: Molecular Marker Development By Bulk Segregant Analysis And Two-State Weighted Gene Co-Expression Network Analysis, Prasit Khunsanit Jan 2024

Salt Tolerance In Rice ‘Jao Khao’: Molecular Marker Development By Bulk Segregant Analysis And Two-State Weighted Gene Co-Expression Network Analysis, Prasit Khunsanit

Chulalongkorn University Theses and Dissertations (Chula ETD)

We validated a QTL based on our previous QTL-Seq mapping study (bulk segregant analysis combined with high-throughput DNA sequencing) using the salt-tolerant donor line ‘Jao Khao’ in a cross of two different genetic backgrounds. The QTL was related to cell membrane stability (CMS) and tiller number (TN), and located in the same interval region of 38.26-38.95 Mb on chromosome 1, indicating pleiotropy. The results confirmed the co-localization of the qCMS1 and qTN1 traits on chromosome 1. Based on the CMS trait, qCMS1/qTN1 stably expressed 6–18% of the phenotypic variance in the two validation populations, while qCMS1/qTN1 accounted for 16–20% of …


Fuzzy Digital Signature Scheme For Binary Noisy Strings With Respect To Hamming Distance, Ittanee Srikham Jan 2024

Fuzzy Digital Signature Scheme For Binary Noisy Strings With Respect To Hamming Distance, Ittanee Srikham

Chulalongkorn University Theses and Dissertations (Chula ETD)

One of the risks associated with public key infrastructure (PKI) pertains to the security of the user's private key. Given the imperative for stringent protection of this key, a proposed solution to mitigate this risk involves the utilization of biometric information. Although biometric information is fuzzy, it cannot be used directly as a cryptographic key. Thus, our investigation commenced into the exploration of ``Signature Scheme with a Fuzzy Private Key" by Takahashi et al. They introduced a new concept of digital signature called ``fuzzy signature" for real vectors with $L_{\infty}$ metric. A fuzzy signature is a signature scheme that uses …


Adjustment Of Ridge Estimator For Linear Regression Model With Multicollinearity, Sittinon Pumpuang Jan 2024

Adjustment Of Ridge Estimator For Linear Regression Model With Multicollinearity, Sittinon Pumpuang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Linear regression model is one of important statistical tools applied in many different problems. Therefore, several studies in developing tools for linear regression models have brought interests from statisticians. One such problem is to find an efficient method for parameter estimation. Several different methods have been proposed in literature such as the ordinary least square method which has been widely used in application. However, the least square estimator has high error when there exists a multicollinearity problem. This, statisticians have developed alternative parameter estimation methods for linear regression models with multicollinearity such as the ridge regression. In this thesis, we …


Fixed Point And Periodic Cycle Of Sequence Arises From Number Of Factors, Thanapong Jaitrakoon Jan 2024

Fixed Point And Periodic Cycle Of Sequence Arises From Number Of Factors, Thanapong Jaitrakoon

Chulalongkorn University Theses and Dissertations (Chula ETD)

Let. {an} and {bn} be sequences of positive integers. For each positive integer n., define an+1 to be the eube of the number of positive factors of an and define bn+1 to be the forth power of the number of positive factors of bn. This thesis proves that (i) if a1 > 1, then (an) eventually becomes the fixed point, namely 21952 or 64000, or {an}eventually becomes a sequence having periodie cycle of prime period 2, namely (64, 343) or (343, 64); (ii) if b1 > 1, then {bn} is eventually the fixed point, namely 625, 6561 or 4100625.


Evaluating The Binding Modes Of Hepatitis B E-Antigen Inhibitor By In Silico Method, Wigrom Yogboworn Jan 2024

Evaluating The Binding Modes Of Hepatitis B E-Antigen Inhibitor By In Silico Method, Wigrom Yogboworn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Hepatitis B, caused by the hepatitis B virus (HBV), is a significant global health concern, primarily affecting the liver and leading to severe complications, including drug resistance and chronic infection. Numerous studies have linked these conditions to the presence of hepatitis B core antigen (HBcAg) and hepatitis B e antigen (HBeAg). HBeAg, in particular, is known to have the innate immune response, resulting in diminished immunity and delayed disease diagnosis and treatment. Despite this, the molecular structure and interactions between inhibitors and HBeAg remain poorly understood, posing a significant challenge to the development of effective treatments. This work employs molecular …


Some Properties Of S-Multiplication Modules And S-Comultiplication Modules, Kanrop Hukaew Jan 2024

Some Properties Of S-Multiplication Modules And S-Comultiplication Modules, Kanrop Hukaew

Chulalongkorn University Theses and Dissertations (Chula ETD)

Let R be an associative ring with identity, and all modules be unitary right R- modules. In 2020, D. D. Anderson et al. introduced the concept of S-multiplication modules, which is a generalization of multiplication modules. Two years later, E. Yildiz et al. introduced the dual notion of S-multiplication modules called S- comultiplication modules. Moreover, S-comultiplication modules are also a gen- eralization of comultiplication modules. In this thesis, we will explore several properties of both S-multiplication modules and S-comultiplication modules. We will provide examples of S-multiplication modules and S-comultiplication modules. Additionally, we demonstrate that the concepts of S-multiplication modules, sim- …


Metallopolymers For Photocatalytic Reduction Of Carbon Dioxide, Wissuta Boonta Jan 2024

Metallopolymers For Photocatalytic Reduction Of Carbon Dioxide, Wissuta Boonta

Chulalongkorn University Theses and Dissertations (Chula ETD)

CdS quantum dots (CdS QDs), acting as photosensitizers, or sometimes solo photocatalysts in CO2 reduction, have offered a myriad of advantages including quantum confinement effect, tunable redox potential, and photoreduction selectivity. However, CdS QDs are frequently compromised by thermal and oxidative instability, as well as photocorrosion, which restricts their practical applications. In this research, an effective method endowing CdS QDs by assembling with amphiphilic metallopolymer was developed to enhance their stability and synergistic activity. The thioglycolic acid-capped cadmium sulfide quantum dots (CdS) were successfully prepared using a simple reflux method. The amphiphilic metallopolymers were successfully synthesized via precise radical polymerization …


ปัจจัยด้านพฤติกรรมของนักแสดงซีรีส์วายกับการยุติการเป็นแฟน, ชรินรัตน์ องค์เพลาเพลิด Jan 2024

ปัจจัยด้านพฤติกรรมของนักแสดงซีรีส์วายกับการยุติการเป็นแฟน, ชรินรัตน์ องค์เพลาเพลิด

Chulalongkorn University Theses and Dissertations (Chula ETD)

การวิจัยนี้มีวัตถุประสงค์เพื่อ (1) ศึกษาระดับผลกระทบของพฤติกรรมนักแสดงซีรีส์วายต่อการตัดสินใจยุติการเป็นแฟน และ (2) วิเคราะห์ปัจจัยที่ทำให้แฟนของนักแสดงซีรีส์วายที่มีประเด็นข่าวเชิงลบตัดสินใจยังคงการเป็นแฟนหรือยุติการเป็นแฟน ผ่านการศึกษาวิจัยเชิงปริมาณและคุณภาพ จากการสํารวจกลุ่มตัวอย่างแฟนคลับนักแสดงซีรีส์วายไทย ทั้งหมด 401 คน และ การสัมภาษณ์เชิงลึกจากแฟนคลับนักแสดงซีรีส์วายไทย ทั้งหมด 14 คน แบ่งเป็น แฟนที่ยังติดตามนักแสดงซีรีส์วายอยู่ จำนวน 6 คน และแฟนที่เลิกติดตามนักแสดงซีรีส์วายด้วยปัจจัยพฤติกรรมจำนวน 8 คน ผลการวิจัยพบว่าปัจจัยหลักด้านพฤติกรรมของนักแสดงซีรีส์วายที่ทำให้แฟนคลับตัดสินใจยุติการเป็นแฟนสูงที่สุด คือ พฤติกรรมที่เกี่ยวข้องกับการล่วงละเมิดทางเพศกับผู้เยาว์ พฤติกรรมที่เกี่ยวข้องกับการข่มขืน พฤติกรรมที่เกี่ยวข้องกับการฉ้อโกง พฤติกรรมที่เกี่ยวข้องกับการอนาจาร ซึ่งหากนักแสดงซีรีส์วายมีพฤติกรรมในกลุ่มนี้ แฟนมีแนวโน้มที่จะยุติการเป็นแฟนในทันที ในขณะที่พฤติกรรมอื่น ๆ อาจจะมีการให้อภัย และยังเป็นแฟนต่อไป โดยขึ้นอยู่กับปัจจัยภายในคือ เพศ อายุ การศึกษา มุมมองที่มีต่อนักแสดง รูปแบบการเป็นแฟน และปัจจัยภายนอกคือ พฤติกรรมในอดีต การตอบสนองของค่าย/ศิลปิน พฤติกรรมที่เกิดขึ้นซ้ำ การเข้าถึงข้อมูลข่าวสาร และคนรอบข้าง/กระแสสังคม ดังนั้นเพื่อป้องกันการยุติการเป็นแฟน นักแสดงซีรีส์วายควรจะสร้างความเชื่อมั่นและความไว้วางใจให้กับแฟน รักษาภาพลักษณ์ที่ดี สื่อสารกับแฟนคลับอย่างสม่ำเสมอ เข้าใจความต้องการของแฟน และพัฒนาตนเองอย่างต่อเนื่อง ส่วนค่ายของนักแสดงควรที่จะให้ความสำคัญกับการคัดเลือกนักแสดงที่มีความสามารถและพฤติกรรมที่ดี วางแผนการตลาดให้เหมาะสมกับภาพลักษณ์ และใส่ใจในเรื่องการจัดการวิกฤตอย่างมีประสิทธิภาพ


The Development Of The Songkran Festival In Thailand: Balancing Tradition, Tourism, And Cultural Identity, Shiyuan Huang Jan 2024

The Development Of The Songkran Festival In Thailand: Balancing Tradition, Tourism, And Cultural Identity, Shiyuan Huang

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research paper examines the development of Thailand’s Songkran Festival over the past decade, with a focus on government policies and the festival's shifting cultural identity. Initially centered on tourism promotion and cultural preservation, Songkran has become part of Thailand’s soft power strategy by 2023, transforming from a local celebration into a global cultural event. The festival's format now features grand, entertainment-driven spectacles, such as the 2024 Maha Songkran World Water Festival, aiming to extend Thailand’s cultural influence internationally. The study further explores the social transformation of Songkran, which, while rooted in traditional values of family and community, has adapted …


Overview Of Music Interventions For Addressing Emotional Distress Among Stroke Patients: A Scoping Review, Xiuqi Shao Jan 2024

Overview Of Music Interventions For Addressing Emotional Distress Among Stroke Patients: A Scoping Review, Xiuqi Shao

Chulalongkorn University Theses and Dissertations (Chula ETD)

Stroke rehabilitation focuses more on restoring function and physical ability and often overlooks the prevalence of psychological symptoms. The prevalence of depression after stroke has been reported to be between 25 and 79 percent. In addition to depression, anxiety, fatigue and apathy are common symptoms after stroke, with a significant overlap in prevalence and symptoms. Music interventions have been reported to evoke and support emotional processes and facilitate engagement in physical movement, making them valuable for stroke rehabilitation. Many studies have investigated the effects of music interventions on negative emotions in stroke patients, but there is still a need for …


Genomic Analysis And Antimicrobial Resistance Of Vibrio Parahaemolyticus Isolated From Seawater At Bang Pu Recreational Center, Samut Prakan Province, Thailand, Chinnawat Assana Jan 2024

Genomic Analysis And Antimicrobial Resistance Of Vibrio Parahaemolyticus Isolated From Seawater At Bang Pu Recreational Center, Samut Prakan Province, Thailand, Chinnawat Assana

Chulalongkorn University Theses and Dissertations (Chula ETD)

Vibrio parahaemolyticus is a foodborne bacterium that is widely distributed in worldwide marine environments including seawater, marine animals, and soils. This study aimed to identify genetic and antimicrobial resistance (AMR) of V. parahaemolyticus (n=46) isolated from seawater at Bang Pu recreational center, Samut Prakan province, Thailand. Genetic analysis from multi-locus sequence typing (MLST) classified the seawater isolates into 42 sequence types (STs) in total, with 29 being novel STs and 13 STs matched with previously reported strains in worldwide including clinical strains (ST356, ST303, STST320, and ST1919) and environmental strains (ST222, ST1083, ST1089, ST969, ST2965, ST2249 and ST233). A phylogenetic …


Effect Of Non-Thermal Plasma On Postharvest Quality Of Tomato, Aishwarya Pant Jan 2024

Effect Of Non-Thermal Plasma On Postharvest Quality Of Tomato, Aishwarya Pant

Chulalongkorn University Theses and Dissertations (Chula ETD)

Microbial attack is a major factor in fruit and vegetable deterioration. One non-thermal method that has shown promise in overcoming these limitations is cold plasma (CP) technology. This study evaluates the impact of dielectric barrier discharge (DBD) cold plasma treatment on the quality, shelf life, and disease incidence of tomatoes. This study was conducted in two stages in this research. Using argon as the working gas, tomatoes were subjected to CP treatment in the first stage for varied power levels (5–20 kV) and times (1–10 minutes). Over a 72-day period, non-destructive studies were conducted to determine disease incidence, marketability, and …


Mass-Ratio-Convex-Combination-Of-Average-Absolute-Deviation-And-Interquartile-Range Based Outlier Factor For Anomaly Scoring, Zehong Fan Jan 2024

Mass-Ratio-Convex-Combination-Of-Average-Absolute-Deviation-And-Interquartile-Range Based Outlier Factor For Anomaly Scoring, Zehong Fan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Anomaly detection is increasingly essential across various sectors, including fraud detection, cybersecurity, and industrial process monitoring, where it serves as an early warning system to identify unusual patterns in data. This research presents a novel, parameter-free anomaly scoring algorithm designed to assign scores to data points without the need for user-defined parameters. The algorithm calculates anomaly scores based on the statistical dispersion of the mass-ratio distribution, utilizing five key measures: variance, range, interquartile range (IQR), average absolute deviation (AAD), and the combination of AAD and IQR. The performance of the proposed Mass-Ratio-Convex-Combination-Of-Average-Absoulte-Deviation-And-Interquartile-Range Based Outlier Factor for anomaly scoring algorithm called …


Virtual Reality Of Labless Machining For Next Industrial Training, Ravee Bunduwongse Jan 2024

Virtual Reality Of Labless Machining For Next Industrial Training, Ravee Bunduwongse

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aims to utilize Virtual Reality (VR) technology to develop an industrial training application with content focusing on Machining operation using lathe machine. The focus of the study is to present the content being taught in manufacturing laboratory classes about lathe machining operations in the virtual world. Development tools include Unity game engine and 3D modeling using Blender. Machining operations demonstrated within this application includes turning, facing, chamfering, grooving, internal and external threading. With 17 out of 18 operations represented in accordance to the actual teaching material, with only external threading deviating from applying threading using the lathe machine …


Virtual Reality Of Labless Welding For Next Industrial Training, Suphakit Anonglekha Jan 2024

Virtual Reality Of Labless Welding For Next Industrial Training, Suphakit Anonglekha

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research introduces an innovative Virtual Reality (VR) application designed to educate users on Welding operations. Its main goals include creating a realistic and immersive learning environment that is also safe. The development process involved the integration of multiple technologies, leveraging the Unity engine and 3D sculpting, all based on extensive research. With all of the type of weld works found in the welding laboratory represented, except the workpiece and electrode material, the VR application accuracy rating is calculated to 94%. The study's significance lies in its contribution to virtual education, especially in fields that require hands-on experience. The VR …


Neural Additive Models For Predicting Her2 Status In Breast Cancer From Immunohistochemical Images, Surayuth Pintawong Jan 2024

Neural Additive Models For Predicting Her2 Status In Breast Cancer From Immunohistochemical Images, Surayuth Pintawong

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study investigated the application of Conformal Prediction (CP) for uncertainty quantifica- tion in Human Epidermal growth factor receptor 2 (HER2) status classification from immunohistochemistry (IHC) images of breast cancer. Although existing machine learning approaches demonstrate high accuracy in predicting HER2 status, they often struggle with borderline cases that require additional testing. We addressed this challenge by implementing a CP framework that generates prediction sets with controlled error rates. Unlike traditional classifiers that provide single predictions, our CP framework can output either singleton predictions for confident cases or multiple labels for uncertain cases, thereby naturally identifying samples that require additional …


Cost-Effectiveness Analysis Of Adjuvant Osimertinib In Resected Egfr-Mutated Early-Stage Non-Small Cell Lung Cancer, Supitchaya Changsatja Jan 2024

Cost-Effectiveness Analysis Of Adjuvant Osimertinib In Resected Egfr-Mutated Early-Stage Non-Small Cell Lung Cancer, Supitchaya Changsatja

Chulalongkorn University Theses and Dissertations (Chula ETD)

Lung cancer is the most common cancer and the leading cause of cancer death worldwide. One-third of non-small cell lung cancer (NSCLC) patients are diagnosed in resectable stage, for which curative surgery is the cornerstone of treatment. Adjuvant osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI), was shown to significantly reduce recurrence and prolong survival for completely resected EGFR-mutated NSCLC. We performed a cost-effectiveness analysis of adjuvant osimertinib compared to placebo in patients with resected stage IB to IIIA EGFR-mutated NSCLC using Thailand’s societal perspective. A Markov model estimated the lifetime costs and health benefits of …


Improved Sequence Embeddings For Peptide-Class I Mhc Binding Prediction, Patiphan Wongklaew Jan 2024

Improved Sequence Embeddings For Peptide-Class I Mhc Binding Prediction, Patiphan Wongklaew

Chulalongkorn University Theses and Dissertations (Chula ETD)

The binding of a peptide antigen to a class I major histocompatibility complex (MHC) protein is considered an essential process by which the immune system monitors infected cells. This mechanism has facilitated the development of peptide-based vaccines aimed at stimulating the patient's immune response for cancer treat-ment. Accurate prediction of peptide-MHC binding is therefore crucial for prioritizing optimal peptides tailored to individual patients. Nevertheless, many MHC alleles lack sufficient experimental data on peptide-MHC binding, which potentially constrains the accuracy of existing prediction models. This study introduces an enhanced iteration of MHCSeqNet, an open-source deep learning model which utilizes sequence data …


Improving Thai-Dialect Automatic Speech Recognition With Curriculum Learning, Artit Suwanbandit Jan 2024

Improving Thai-Dialect Automatic Speech Recognition With Curriculum Learning, Artit Suwanbandit

Chulalongkorn University Theses and Dissertations (Chula ETD)

Automatic Speech Recognition (ASR) has been the foremost feature and integrated in many real-world usages for decades. The novel deep learning approaches prevail in the ASR field as a model architecture. However, ASR still struggles with low-resource data, especially in the Thai dialectal language. Transfer learning is the conventional approach in the machine learning field for escalating the performance of low-resource settings. In the scenario that additional fine-tuning tasks are not achievable, exerting all efficiency of target data is an accountability. To overcome stagnation, we proposed transfer-based curriculum learning for low-resource dialectal ASR, Phonemetically-induced subword Out-of-vocabulary rate (PhIS-OOV), and Model …


Grammatical Error Correction In Thai Sentences For Deaf Students, Supachan Traitruengsakul Jan 2024

Grammatical Error Correction In Thai Sentences For Deaf Students, Supachan Traitruengsakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Deaf students encounter challenges in written communication due to errors such as insertion, deletion, disorder, misusage, and misspellings. Grammatical error correction (GEC) technology can help mitigate these issues. However, existing GEC models are primarily trained on online resources from second-language hearing learners. In contrast, sentences written by deaf students suffer from a variety of errors not typically found elsewhere. To address this issue, we create the Thai Deaf Corpus (TDC), focusing on identifying and analyzing errors among deaf students in grades 7-12 across four deaf schools. Additionally, we introduce a two-stage system for the Thai-GEC model, automatically detecting and correcting …


Chinese Consumers’ Perception Of Thailand As A Tourism Destination Via Xiaohongshu Platform, Zihuan Xu Jan 2024

Chinese Consumers’ Perception Of Thailand As A Tourism Destination Via Xiaohongshu Platform, Zihuan Xu

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study examines how prior travel experience, demographic factors, and user-generated content (UGC) on Xiaohongshu collectively influence Chinese consumers’ perceptions of Thailand as a tourist destination, with a focus on shopping. Consumer perception is analyzed across four dimensions: cognition, emotion, language, and behavior. The findings reveal that prior travel experience has the most significant impact, with those who have visited Thailand showing more positive perceptions across all dimensions compared to those who have not. Demographic factors, such as age and occupation, also play a role, particularly in influencing language. Exposure to Xiaohongshu UGC primarily affects the behavioral dimension, enhancing purchase …


Fans Perceptions And Fans Engagement Of “Bed Friend Series”, Fiona Paramatmika Jan 2024

Fans Perceptions And Fans Engagement Of “Bed Friend Series”, Fiona Paramatmika

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objective of the research is to explore the fan perception and fan engagement of “Bed Friend Series”. The research used In-depth interview method from 20 key informants from the fandom living in different countries. The research examines how fans perceive the series’ themes, characters, and storylines, as well as their interaction with its leading actors, Net Siraphop and James Su. Utilizing qualitative methods, twenty informants from diverse backgrounds were interviewed to understand their emotional connections and participatory behaviors across online and offline platforms. Findings reveal that fans hold the series in high regard for its portrayal of relationships and …


Indian Tourists’ Perceptions Of Inclusive Tourism In Thailand With A Focus On Media Influence And Cultural Differences, Shikha Patwal Jan 2024

Indian Tourists’ Perceptions Of Inclusive Tourism In Thailand With A Focus On Media Influence And Cultural Differences, Shikha Patwal

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study examined Indian tourists’ perceptions of LGBTQ+ inclusivity in Thailand, with a focus on the roles of media influence and cultural differences. As Thailand is a prominent destination for LGBTQ+ tourism in Southeast Asia, understanding how cultural nuances impact Indian tourists' experiences offers valuable insights. The research employs a qualitative approach, gathering data through in-depth interviews with 10 Indian tourists who have visited Thailand. The findings suggest that Indian tourists generally perceive Thailand as a welcoming and safe space for LGBTQ+ individuals, contrasting with India’s more conservative social landscape. Media representations, including social media, significantly shape expectations of inclusivity, …