Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (1690)
- Engineering (1183)
- Physical Sciences and Mathematics (1117)
- Social and Behavioral Sciences (951)
- Chemical Engineering (511)
-
- Arts and Humanities (469)
- Chemistry (431)
- Life Sciences (410)
- Business (353)
- Economics (336)
- Medical Sciences (335)
- Dentistry (299)
- Veterinary Medicine (280)
- Pharmacy and Pharmaceutical Sciences (274)
- Public Health (272)
- Finance and Financial Management (271)
- Computer Sciences (258)
- Education (241)
- Sociology (177)
- Civil and Environmental Engineering (175)
- Mathematics (158)
- Environmental Sciences (141)
- Law (141)
- Communication (134)
- Communication Technology and New Media (134)
- Mass Communication (134)
- Electrical and Computer Engineering (121)
- Operations Research, Systems Engineering and Industrial Engineering (116)
- English Language and Literature (113)
- Industrial Engineering (113)
Articles 871 - 900 of 6471
Full-Text Articles in Entire DC Network
The Implications Of The Visa Exemption For Sino-Thai Relations, Kaiting Liang
The Implications Of The Visa Exemption For Sino-Thai Relations, Kaiting Liang
Chulalongkorn University Theses and Dissertations (Chula ETD)
นโยบายยกเว้นวีซ่าระหว่างไทยและจีนซึ่งมีผลตั้งแต่วันที่ 1 มีนาคม 2567 ถือเป็นก้าวสำคัญในความสัมพันธ์ทวิภาคี โดยนโยบายนี้ส่งเสริมการท่องเที่ยวร่วมกัน เพิ่มพูนการแลกเปลี่ยนวัฒนธรรม และเสริมสร้างความสัมพันธ์ทางเศรษฐกิจด้วยการอำนวยความสะดวกในการเดินทางโดยไม่ต้องขอวีซ่าเป็นระยะเวลาไม่เกิน 30 วันสำหรับพลเมืองของทั้งสองประเทศ โครงการนี้มุ่งหวังกระตุ้นการท่องเที่ยวหลังการระบาดใหญ่ โดยคาดว่าจะมีนักท่องเที่ยวชาวจีนเยือนไทยถึง 8 ล้านคนในปี 2567 การวิจัยนี้สำรวจผลกระทบทางสังคมและเศรษฐกิจของนโยบาย รวมถึงผลต่อการท่องเที่ยว การค้า และการแลกเปลี่ยนวัฒนธรรม แม้ว่าจะมีประโยชน์ทางเศรษฐกิจอย่างมหาศาล แต่ก็มีความท้าทาย เช่น ความกังวลด้านความปลอดภัย การท่องเที่ยวเกินขีดจำกัด และการพึ่งพาตลาดเดียว โดยมีข้อเสนอแนะเพื่อปรับปรุงนโยบายอย่างยั่งยืน เช่น การกระจายตลาดการท่องเที่ยว การพัฒนาสาธารณูปโภค และการส่งเสริมความร่วมมือทวิภาคี การศึกษานี้มีส่วนสำคัญในการทำความเข้าใจว่านโยบายวีซ่าสามารถเป็นเครื่องมือในการเสริมสร้างความสัมพันธ์ทางการทูตและเศรษฐกิจระหว่างประเทศได้อย่างไร
Effects Of The Integrative Information-Motivation-Behavioral Skills Program On Body Mass Index And Body Image Among University Personnel With Obesity, Pornsuang Chotchuang
Effects Of The Integrative Information-Motivation-Behavioral Skills Program On Body Mass Index And Body Image Among University Personnel With Obesity, Pornsuang Chotchuang
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study employed a clustered randomized controlled trial (RCT) to examine the effectiveness of the Integrative Information-Motivation-Behavioral Skills (IIMBS) program on body mass index (BMI) and body image among university personnel obesity. Participants were 64 university personnel of Suratthani Rajabhat University, who were divided equally by clustered random sampling into an intervention and a control group. The 12-week Integrative Information-Motivation-Behavioral Skills (IIMBS) program based on Information-Motivation-Behavioral Skills model (Fisher & Fisher, 1992). It was used via face-to-face sessions and “Belly to Healthy Shape” LINE OA. The research instruments consisted of a demographic questionnaire, Thai-version Body Shape Questionnaire (BSQ-34), and the …
The Effect Of The Individual And Family Self-Mannagement Program On Medication Adherence Among School-Aged Children With Epilepsy., Chutimaporn Kangwal
The Effect Of The Individual And Family Self-Mannagement Program On Medication Adherence Among School-Aged Children With Epilepsy., Chutimaporn Kangwal
Chulalongkorn University Theses and Dissertations (Chula ETD)
This randomized controlled trial with repeated measures compared medication adherence among school-aged children with epilepsy who received the Individual and Family Self-Management (IFSM) program versus standard nursing care at baseline, post-test, week 8, and week 12. Sixty-two eligible children and their families were randomly assigned to experimental (n=31) and control groups (n=31) using block randomization. The 12-week IFSM program, based on Ryan and Sawin's (2009) Individual and Family Self-Management theory, focused on (1) accurate knowledge and beliefs, (2) self-regulation skills, and (3) social facilitation. The intervention included face-to-face sessions, activities via the “KanChak” LINE Official Account, and booster sessions with …
The Effect Of A Culture Based Breast Health Education Program On Breast Self-Examination Practice Among High-Risk Adult Pakistani Women, Sumaira Naz
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study aimed to determine the effect of a culture-based breast health education program on breast self-examination practice (BSEP) in high-risk women through a randomized controlled trail (RCT). The participants of 72 high -risk women, aged 20-50 years from POF hospital, Taxila was taken on matched pairs with age and educational level and randomly assigned into an experimental and a control group. The program was developed on social cognitive theory (SCT) (Bandura, 1977, 1989), and the cultural identity concept of PEN-3 model (Airhihenbuwa,1989). The intervention group received the culture-based breast health education program, while control group received usual care. BSEP …
Parenting Styles And Behavioral Problems In Preschoolers, Sansanee Sutthi
Parenting Styles And Behavioral Problems In Preschoolers, Sansanee Sutthi
Chulalongkorn University Theses and Dissertations (Chula ETD)
This dissertation examines the impact of hidden violent punishment within diverse parenting styles in Thai society, focusing on preschool children aged 3 to 4 years (36 to 59 months). Utilizing the Thailand Multiple Indicator Cluster Survey 2019 (MICS6/2019) national dataset (N=5,345), the study addresses three primary research objectives:1) examine the key factors and parenting styles influencing child behavioral problems, 2) investigate the associations between socioeconomic characteristics and parenting styles, and 3) generate a model for enhancing parenting factors that mitigate behavior problems in preschoolers. The study employs advanced statistical methodologies, including probit regression to analyze factors which influence behavior problems …
Knowledge Attitudes And Practices Toward Tuberculosis Prevention Among Undergraduate Students In Bangkok, Thailand: A Cross-Sectional Study, Ziqing Xu
Chulalongkorn University Theses and Dissertations (Chula ETD)
Tuberculosis (TB) is still a significant global public health concern, particularly in resource-limited countries. Even WHO set the targets of the End tuberculosis (TB) by 2030, the global trend in TB case incidence becomes increase including in Southeast Asian region. The newly diagnosed tuberculosis patients are highly reported in 15-24 age group. Understanding the knowledge and attitudes on TB and preventive practice of the population at risk is crucial for developing health education intervention to prevent the disease transmission. This study was a cross-sectional study. Data were collected from 424 undergraduate students aged 18-24 years at five universities (including public …
An Academic Management Innovation Of Demonstration Schools For Enhancing Future Global Citizenship Competencies, Sathibhoph Somtua
An Academic Management Innovation Of Demonstration Schools For Enhancing Future Global Citizenship Competencies, Sathibhoph Somtua
Chulalongkorn University Theses and Dissertations (Chula ETD)
This research aimed to 1) study the conceptual framework of academic management and future global citizenship competencies, 2) study the levels of students’ future global citizenship competencies, 3) analyze the priority needs in developing academic management of demonstration schools for enhancing future global citizenship competencies, and 4) to develop an academic management innovation for enhancing future global citizenship competencies of demonstration schools. This study employed a multi-phase mixed-method design, combining quantitative and qualitative data collection. The sample consisted of 68 demonstration schools. Informants included the demonstration school director, the deputy director of academics, and the head of the department. The …
Lightweight Neural Network Pipeline Model For Drone Collision Prediction System Using Limited Computing Resources, Rifqi Nabila Zufar
Lightweight Neural Network Pipeline Model For Drone Collision Prediction System Using Limited Computing Resources, Rifqi Nabila Zufar
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis focuses on developing a drone collision prediction algorithm by adapting the Neural Network Pipeline (NNP) for use in limited computing resources devices. While NNP is effective with sufficient computation, its performance in constrained environments remains untested. To address this issue, an adaptation of NNP using post-training quantization is developed. This method effectively compresses the model by reducing the precision of the 32-bit floating point. This adaptation aims at reducing model complexity and offers significant benefits in terms of reduced model size, increased processing speed, and reduced power consumption. It results in the expense of prediction accuracy. The MobileNetV3Small …
Study On Skin Cancer Classification Architectures Based-On Cnn With Channel And Spatial Attention Mechanism, Zahid Maqbool
Study On Skin Cancer Classification Architectures Based-On Cnn With Channel And Spatial Attention Mechanism, Zahid Maqbool
Chulalongkorn University Theses and Dissertations (Chula ETD)
The early and accurate detection of skin cancer is crucial for effective treatment and improving patient survival rates. This research explores innovative CNN-based architectures enhanced with Channel Attention and Spatial Attention (CASA) mechanisms for classifying skin cancer types from dermoscopic images. Building on the strengths of transfer learning, the study applies pre-trained models VGG16, InceptionResNetV2, and EfficientNet variants (EfficientNet B0 to B7) and customizes them for skin cancer classification using CASA modules. The CASA integration allows the models to selectively focus on critical features within images, enhancing both spatial and channel-based feature extraction. Experiments utilize the HAM10000 dataset. Which contains …
Enhanced Cross-Modality Mri Segmentation Using Dilated Convolutions And Multi-Scale Gradient Map, Ghulam Murtaza
Enhanced Cross-Modality Mri Segmentation Using Dilated Convolutions And Multi-Scale Gradient Map, Ghulam Murtaza
Chulalongkorn University Theses and Dissertations (Chula ETD)
Magnetic resonance imaging (MRI) segmentation is critical for accurate medical diagnosis, but cross-modal segmentation presents significant challenges due to domain shifts between imaging modalities and limited labeled data. This study proposes an enhanced U-Net framework designed to improve segmentation accuracy and generalization across different MRI modalities. The method incorporates dilated convolutions in the encoder to expand the receptive field, allowing for better contextual information capture without increasing the number of parameters. Additionally, squeeze and excite (SE) blocks are introduced to recalibrate channel-wise feature importance, addressing variations in tissue contrast across modalities. A multi-scale gradient map fusion strategy, based on holistic …
Classification Of Bearing Failure In Adverse Industrial Conditions, Bawar Masih
Classification Of Bearing Failure In Adverse Industrial Conditions, Bawar Masih
Chulalongkorn University Theses and Dissertations (Chula ETD)
In industrial environments, the detection of machinery reliability is frequently compromised by surrounding noise. This interference can lead to unexpected machine failures, resulting in costly downtime and extensive repair expenses. This study investigates the application of CNN and LSTM networks for fault diagnosis under noisy conditions to achieve high classification accuracy across varying SNRs. The CNN model, designed to capture localized features, proved particularly effective in extracting critical information from complex vibration data despite substantial background noise. In contrast, the LSTM model, while optimized for sequential data analysis, showed limited performance under high-noise conditions. Using the CWRU Bearing dataset, the …
Small Object Detection Techniques In Remote Sensing Images Using Aam And Raspp, Farhan Iqbal
Small Object Detection Techniques In Remote Sensing Images Using Aam And Raspp, Farhan Iqbal
Chulalongkorn University Theses and Dissertations (Chula ETD)
Remote sensing technology has advanced substantially, with significant research focused on identifying and recognizing small, distant objects within large-scale scenes. Despite these strides, the task remains difficult due to limitations in image resolution, varied object scales, dense object distribution, and diverse orientations. Current object detection methods often struggle to maintain the fine detail essential for small object detection, resulting in the loss of critical information. To address this, we introduce an Advanced Attention Mechanism (AAM) that combines a novel Combined Channel and Spatial Attention (CCSA) approach with Residual Atrous Spatial Pyramid Pooling (RASSP). This integration enhances detection accuracy by preserving …
Characterization Of Size Distribution And Source Contribution To Airborne Particles In Buddhist Religious Places In Bangkok, Sopannha Chy
Characterization Of Size Distribution And Source Contribution To Airborne Particles In Buddhist Religious Places In Bangkok, Sopannha Chy
Chulalongkorn University Theses and Dissertations (Chula ETD)
Ultrafine particles, defined as particles with diameter below 100 nm, present high health risks but presently remain unknown in air quality management in Thailand. To better understand ultrafine particles, the appropriate quantification must be by aerosol numbers in a size-resolved manner in addition to the mass-based information currently used. This study investigated the particle number concentration and size distribution as well as estimating the source emission rate from incense burning in 3 temples and 1 shrine located in Bangkok, Thailand on peak days and normal day from 10 a.m. to 5 p.m. The Scanning Mobility Particle Sizer (SMPS) and the …
"Adaptive Signal Control For Reducing The Effect Of Queue Spillback", Eamlong Tang
"Adaptive Signal Control For Reducing The Effect Of Queue Spillback", Eamlong Tang
Chulalongkorn University Theses and Dissertations (Chula ETD)
Urban traffic congestion at signalized intersections poses significant challenges, with queue spillback events worsening delays, fuel consumption, and environmental impacts. This study addresses the critical issue of oversaturation at the Rama 4 intersection in Bangkok, where closely spaced intersections intensify congestion, leading to prolonged queues and inefficient green phase utilization. Traditional fixed-time signal controls lack the flexibility to adapt to fluctuating traffic volumes, emphasizing the need for an innovative approach. This research proposes an Adaptive Signal Control (ASC) scheme, utilizing VISSIM and VISVAP simulation tools to evaluate the system’s efficacy in managing real-time traffic conditions and reducing queue spillback events. …
Private Motorcycle Users' Insights Toward Public Bus Adoption In Phnom Penh, Eangthay Tang
Private Motorcycle Users' Insights Toward Public Bus Adoption In Phnom Penh, Eangthay Tang
Chulalongkorn University Theses and Dissertations (Chula ETD)
As Phnom Penh experiences rapid population growth and economic expansion, traffic congestion has worsened, largely due to the increasing ownership of private motorcycles. Despite the introduction of public bus services, adoption remains low as concerns over service quality, limited coverage, and inadequate infrastructure deter motorcycle users from making the shift. This study investigates the behavioral intentions, preferences, and concerns of motorcycle users, specifically targeting university students, to understand how public bus services can be improved to encourage adoption. Data were collected in July 2024 from 457 university students who regularly use motorcycles, using a structured questionnaire across four Phnom Penh …
The Effects Of Uv-Radiation On The Removal Of Microplastics In Water Using Agglomeration-Micro-Flotation, Palot Srichonphaisarn
The Effects Of Uv-Radiation On The Removal Of Microplastics In Water Using Agglomeration-Micro-Flotation, Palot Srichonphaisarn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Microplastics, plastic particles with diameter 1 micrometer to 5 millimeters, can disturb marine ecosystems due to their small size and surface properties which can be a carrier for hazardous matters. While wastewater treatment plants could remove some microplastics but some of them remain. Among the various removal techniques, flotation is a potential method due to the hydrophobic nature of microplastics. This study investigates the effects of ultraviolet radiation on the surface wettability of microplastics and removal efficiency of microplastics. The 6 types of microplastics were prepared from plastic boards. After the ultraviolet radiation, the results showed that ultraviolet radiation could …
Effect Of Zeolite Support Of Nickel-Copper Catalyst On Conversion Of Palm Oil To Sustainable Aviation Fuel, Natnicha Ritmun
Effect Of Zeolite Support Of Nickel-Copper Catalyst On Conversion Of Palm Oil To Sustainable Aviation Fuel, Natnicha Ritmun
Chulalongkorn University Theses and Dissertations (Chula ETD)
Sustainable aviation fuel (SAF) is increasingly recognized as a critical alternative for reducing the environmental impact of the aviation industry, which is a significant source of global greenhouse gas emissions. SAF production primarily utilizes vegetable oils as feedstock rather than biomass, due to their low functional group content and chemical structure that closely resembles that of fossil fuels. This research focuses on the development of bimetallic catalysts made from nickel, with copper as promoters, supported on various zeolites including SAPO-11, Zeolite Y, and Zeolite ZSM-5. The chemical and physical properties of these catalysts were analyzed using several techniques, including X-ray …
Multiplex Quantitative Polymerase Chain Reaction Assay For Mycoplasma Contamination, Pimthip Phasutha
Multiplex Quantitative Polymerase Chain Reaction Assay For Mycoplasma Contamination, Pimthip Phasutha
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study aims to develop multiplex qPCR to detect mycoplasma contamination. Firstly, the specific primers and probes for aligning with specific mycoplasma. were designed from conserved region called 23S rRNA, then, the designed primers and probes were verified their alignment with specific nucleotide of mycoplasma in Bioedit and checked the hairpin, self-complementary, and primer-dimer through Multi Primer Analyzer. After verification, the primers and probes do not have hairpin, self-complementary, and primer-dimer. Besides, the suitable temperature for annealing is 58oC. From the specificity test, it shows that the PCR product was detected at 254 bp which performed at the same size …
The Efficacy Of Plant-Produced Recombinant Insulin Like Growth Factor-1 (Igf-1) In Differentiation Of Mammalian Cell Lines, Kittinop Kittirotruji
The Efficacy Of Plant-Produced Recombinant Insulin Like Growth Factor-1 (Igf-1) In Differentiation Of Mammalian Cell Lines, Kittinop Kittirotruji
Chulalongkorn University Theses and Dissertations (Chula ETD)
Insulin-like growth factor-1 (IGF-1) is a critical protein hormone with a structural resemblance to insulin, involved in regulating growth, cell proliferation, development, and survival, especially during childhood. IGF-1 exerts its biological effects through the IGF-1 receptor (IGF-1R), widely expressed across various cell types, and is key in the development of muscles, bones, and cartilage. The hormone's levels are influenced by age, nutrition, and hormonal status, peaking during adolescence and diminishing with age. Current medical applications of IGF-1 target conditions such as IGF-1 deficiency, excess growth hormone secretion, and metabolic disorders. To address production challenges, we utilized Molecular Pharming to produce …
The Impact Of N-Glycans On The Immune Response Of Plant-Produced Sars-Cov-2 Rbd-Fc Proteins, Theerakarn Srisangsung
The Impact Of N-Glycans On The Immune Response Of Plant-Produced Sars-Cov-2 Rbd-Fc Proteins, Theerakarn Srisangsung
Chulalongkorn University Theses and Dissertations (Chula ETD)
N-glycosylation is a crucial post-translational modification that significantly affects immune recognition. The plant-based platform, especially Nicotiana benthamiana, offers scalable and cost-effective production of therapeutic proteins with glycosylation patterns similar to mammalian cells. However, plant-specific N-glycans, such as α(1-3)-fucose and β(1-2)-xylose (XF), have the potential to trigger allergic reactions. This study investigates how various N-glycan structures on the RBD-Fc fusion protein influence the immune response in mice. The RBD-Fc fusion protein was used for vaccine formulation, produced in both wild-type (WT) and glycoengineered (∆XF) N. benthamiana plants. N-glycan analysis showed a predominance of mannose (Man) in RBD-Fc with an ER retention …
Characterization Of Plant Produced Vhh Antibodies Against Cobra Venom Toxins For Antivenom Therapy, Sarocha Vitayathikornnasak
Characterization Of Plant Produced Vhh Antibodies Against Cobra Venom Toxins For Antivenom Therapy, Sarocha Vitayathikornnasak
Chulalongkorn University Theses and Dissertations (Chula ETD)
Cobra (Naja kaouthia) venom contains many toxins including α-neurotoxin (α-NTX) and phospholipase A2 (PLA2), which can cause neurodegeneration, respiratory failure, and even death. The conventional antivenom produced by animal immunization faces many challenges and limitations. Heavy-chain-only antibodies (HCAb), fusing VHH with human IgG Fc region, offer advantages in tissue penetration, antigen binding, and extended half-life. This research involved the construction and transient expression of two types of VHH-FC which are specific to α-Neurotoxin (VHH-αNTX-FC) and Phospholipase A2 (VHH-PLA2-FC) in Nicotiana benthamiana leaves. The recombinant HCAbs were incubated for up to six days to optimize expression levels followed by purification by …
Cost-Effectiveness Analysis Of Pembrolizumab In High-Risk Early-Stage Triple-Negative Breast Cancer In Thailand, Thanapol Khuharatanachai
Cost-Effectiveness Analysis Of Pembrolizumab In High-Risk Early-Stage Triple-Negative Breast Cancer In Thailand, Thanapol Khuharatanachai
Chulalongkorn University Theses and Dissertations (Chula ETD)
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited treatment options. Pembrolizumab, a programmed cell death protein 1 (PD-1) inhibitor, has demonstrated promising clinical benefits in treating early-stage TNBC. However, its high cost poses a significant barrier to its widespread adoption, especially in upper-middle-income countries like Thailand. This study aims to evaluate the cost-effectiveness and budget impact of pembrolizumab for the treatment of high-risk early-stage TNBC in Thailand. Methods: A Markov model was developed to simulate the health states and costs associated with pembrolizumab and standard chemotherapy. Transition probabilities and utility values were derived from …
Production And Characterization Of Monoclonal Antibodies Against Botulinum Toxin Produced In Nicotiana Benthamiana, Kornchanok Sangprasat
Production And Characterization Of Monoclonal Antibodies Against Botulinum Toxin Produced In Nicotiana Benthamiana, Kornchanok Sangprasat
Chulalongkorn University Theses and Dissertations (Chula ETD)
Botulism is an uncommon but serious neurological condition caused by the botulinum toxin produced by the gram-positive bacterium named Clostridium botulinum. Common symptoms of botulism include muscle cramps, nausea, vomiting, diarrhea, difficulty swallowing, respiratory failure, muscle weakness, and potentially death. Currently, two types of antitoxin are used: equine-derived heptavalent antitoxin and human-derived immunoglobulin (BabyBIG®). However, treatment with heptavalent antitoxin may lead to hypersensitivity reactions, while BabyBIG®, which is produced in low yield, is used only for children. This research focuses on developing three anti-BoNT monoclonal antibodies (mAbs), 1B18, C25, and M2, which will be produced using Nicotiana benthamiana as a …
สารัตถะเพลงครอบจักรวาลกับการแปรทำนองซอสามสายของรองศาสตราจารย์พิชิต ชัยเสรี, สุนทรวินิจ วรสิงห์
สารัตถะเพลงครอบจักรวาลกับการแปรทำนองซอสามสายของรองศาสตราจารย์พิชิต ชัยเสรี, สุนทรวินิจ วรสิงห์
Chulalongkorn University Theses and Dissertations (Chula ETD)
งานวิจัยเรื่องสารัตถะเพลงครอบจักรวาลกับการสร้างทำนองซอสามสายของ รองศาสตราจารย์พิชิต ชัยเสรี มีวัตถุประสงค์เพื่อศึกษาวิธีการสร้างทำนองซอสามสาย และ เพื่อศึกษากลวิธีการแปรทำนองซอสามสายจากทำนองทางฆ้องกรณีศึกษาเพลงครอบจักรวาล ผลการวิจัยพบว่า สามารถสร้างทำนองซอสามสายได้โดยวิธีการ 4 ขั้นตอน ดังนี้ (1.) การแปลทำนองฆ้องเป็นทำนองซอสามสาย (Translation) โดยวิธีการถอดทำนองฆ้องเป็นทำนองสารัตถะ จากนั้นพิจารณาทิศทางการดำเนินของทำนองใน 3 รูปแบบคือ วิถีขึ้น (Way Up) วิถีลง (Way Down) และวิถีคงที่ (Stand Still) สามารถแปลทำนองได้เป็น 2 ลักษณะ คือการแปลอย่างจาว (Thin Texture) และการแปลอย่างเก็บ (Thick Texture) (2.) การแปรทำนองซอสามสาย (Variation) ให้เกิดความหลากหลายของทำนองออกไปจากทำนองอย่างเดิม (3.) การผูกสำนวนทำนอง (Combination) เรียงร้อยสำนวนทำนองระหว่างมือฆ้องเข้าไว้ด้วยกันโดยใช้ความรู้จากการแปลและการแปรทำนอง (4.) การสร้างสรรค์ทำนอง (Creativity) ใช้ความรู้จากทั้ง 3 ขั้นตอนที่ได้กล่าวมารวมทั้งประสบการณ์ในการสร้างทำนองใหม่เพื่อให้เกิดทำนองซอสามสายที่ดีและไพเราะน่าฟัง กลวิธีการแปรทำนองซอสามสาย เสนอไว้ 3 ประการ ประการแรก เสียงซ้ำให้หลีกหนีประการที่สอง เพิ่มเสียงตามกลุ่มเสียงและสร้างความถี่ของโน้ต และประการสุดท้าย ทำความผันแปรของทิศทางการดำเนินทำนอง
Disciplining The Responses To Cross-Border Subsidies: The Case Study Of Eu And Us Trade Remedy Investigations Against Products From Indonesia And Thailand, Jia Zhen Cen
Chulalongkorn University Theses and Dissertations (Chula ETD)
The geopolitical confrontation between the United States and China extends across various levels and domains, with trade being one of the most prominent arenas. Subsidies, a longstanding source of contention in international trade, have become an even more contentious issue following China’s launch of the Belt and Road Initiative (BRI) in 2013. Traditionally, subsidies are provided by a government to its domestic producers, and WTO subsidy rules allow its Members to take countervailing measures against subsidies of their direct trading partners when those subsidies cause injury to the Member's domestic industries. However, the rise in cross-border subsidies – where governments …
การตีความข้อยกเว้นด้านความมั่นคงมาตรา Xxi(B) ขององค์การการค้าโลก, นิธินันท์ ลีธนะกุล
การตีความข้อยกเว้นด้านความมั่นคงมาตรา Xxi(B) ขององค์การการค้าโลก, นิธินันท์ ลีธนะกุล
Chulalongkorn University Theses and Dissertations (Chula ETD)
ข้อยกเว้นด้านความมั่นคงตามมาตรา XXI(b) แห่งความตกลงองค์การการค้าโลก (WTO) ทวีความสำคัญขึ้นในปัจจุบัน เนื่องจากประเทศสมาชิกนำมาใช้เป็นเครื่องมือจำกัดการค้าระหว่างประเทศมากขึ้น การศึกษานี้มุ่งวิเคราะห์การตีความและการบังคับใช้ข้อยกเว้นดังกล่าว โดยเปรียบเทียบกับบทบัญญัติมาตรการที่กระทำได้ (Non-Precluded Measures Clause: NPM) ในกฎหมายการลงทุนระหว่างประเทศ โดยตั้งสมมติฐานว่าการพิจารณาเพียงเงื่อนไขตาม (i)-(iii) ของมาตรา XXI(b) เป็นเกณฑ์ที่อาจทำให้ประเทศสมาชิกยกอ้างข้อยกเว้นความมั่นคงได้โดยง่ายเกินไป การศึกษาใช้วิธีวิจัยเชิงเอกสารโดยวิเคราะห์คำวินิจฉัยของคณะกรรมการระงับข้อพิพาทของ WTO คำชี้ขาดของคณะอนุญาโตตุลาการด้านการลงทุนระหว่างประเทศ ตลอดจนประวัติการเจรจาและวัตถุประสงค์ของมาตรา XXI ผลการศึกษาพบว่า WTO ยังขาดกฎเกณฑ์ที่ชัดเจนในการตรวจสอบการใช้ดุลพินิจของรัฐ แม้ไม่อาจนำกฎเกณฑ์ของกฎหมายการลงทุนระหว่างประเทศมาใช้โดยตรงเนื่องจากลักษณะธุรกรรมและความสัมพันธ์ที่แตกต่างกัน แต่มีส่วนที่สอดคล้องกันคือการใช้วลี "it considers necessary" ที่สะท้อนลักษณะบทบัญญัติแบบอัตวินิจฉัย (self-judging) ทั้งนี้ แนวปฏิบัติจากกฎหมายการลงทุนระหว่างประเทศสามารถนำมาประยุกต์ใช้ในการตรวจสอบการใช้ดุลพินิจของรัฐภายใต้กรอบ WTO ในส่วนของหลักสุจริตได้ อย่างไรก็ตาม ความกังวลสำคัญคือการใช้ข้อยกเว้นด้านความมั่นคงในทางที่ผิดอย่างต่อเนื่อง อาจทำให้ข้อยกเว้นกลายเป็นหลักปฏิบัติปกติ ซึ่งทำลายเจตนารมณ์ดั้งเดิมและส่งผลกระทบต่อเสถียรภาพของระบบการค้าระหว่างประเทศ การศึกษานี้จึงเสนอแนะให้พัฒนาแนวทางการตีความที่ชัดเจนขึ้น สร้างกลไกการตรวจสอบที่มีประสิทธิภาพ และสร้างความสมดุลระหว่างการคุ้มครองผลประโยชน์ด้านความมั่นคงของรัฐและการรักษาเสถียรภาพของระบบการค้าระหว่างประเทศ
Capm With Independent Regimes For The Alpha And Beta And An Application In Portfolio Optimization, Suwapith Payakapong
Capm With Independent Regimes For The Alpha And Beta And An Application In Portfolio Optimization, Suwapith Payakapong
Chulalongkorn University Theses and Dissertations (Chula ETD)
We develop a regime-dependent Capital Asset Pricing Model (CAPM), in which alpha and beta follow independent regime-switching processes, and use it in the mean-variance optimization (MVO) framework. Although the model does not significantly improve predictive metrics, we find that the predicted returns from the model have a larger rank correlation with the realized future returns than those from the historical mean and the common-regime CAPM, which assumes shared regime shifts between alpha and beta. The mean-variance portfolio derived from our model yields a superior out-of-sample risk-adjusted return compared to the portfolios derived from the equal-weight strategy, market index replication, the …
The Prognostic Impact Of Various Circulating Cytokine Levels On Response To Egfr-Tkis Treatment In Advanced Nsclc Patients, Warissara Khuntharuks
The Prognostic Impact Of Various Circulating Cytokine Levels On Response To Egfr-Tkis Treatment In Advanced Nsclc Patients, Warissara Khuntharuks
Chulalongkorn University Theses and Dissertations (Chula ETD)
Advanced NSCLC patients are routinely treated with EGFR-TKIs but often eventually develop acquired resistance, influenced by circulating cytokines. This study investigated cytokine associations with disease control in EGFR-mutant NSCLC patients (N=123) by analyzing plasma samples at pre-treatment and 6–12 weeks post-treatment using a 27-bioplex cytokine panel, compared with healthy controls (N=30). Patients were classified as durable responders (16.3%) (PFS ≥ 104 weeks) and non-durable responders (83.7%) (PFS<104 weeks). Notably, IL-1Ra, IL2, IL-6, IL-7, IL-12p(70), TNF- alpha, IL-4, IL-5, IL-8, IL-13, Eotaxin, IP-10, MIP-1 alpha, RANTES, Basic FGF, GM-CSF and PDGF-BB were significantly presented with high levels in the patient’s pre-treatment plasma compared to healthy controls (p<0.05). High IL-6 and IL-10 levels were significant in non-durable responders (p = 0.0076 and p = 0.0166, respectively). At second-time points, non-durable responders exhibited significantly lower IL-6 levels (p=0.0019), whereas durable responders showed increased IL-10 (p = 0.0234). High pre-treatment IL-6 correlated with poor PFS (p=0.018), OS (p<0.001), and TTF (p<0.001). Consistently, high IL-10 was also correlated with shorter TTF (p<0.005). IL-6 and IL-10 showed strong diagnostic performance (AUC with 0.755 and 0.738, respectively). These cytokines may serve as prognostic biomarkers for evaluating durable EGFR-TKI responses in NSCLC patients.
Development Of Cannabis Extract Active Coating On Granules With Taste Masking Polymer Via Fluidized Bed, Samuel Wirajaya Prawinata
Development Of Cannabis Extract Active Coating On Granules With Taste Masking Polymer Via Fluidized Bed, Samuel Wirajaya Prawinata
Chulalongkorn University Theses and Dissertations (Chula ETD)
Abstract Cannabis extract, one of the herbal medicine products on the national list of essential medicines, offers various therapeutic benefits; however, it has unpleasant taste, and the products are available as liquid preparation which can significantly reduce patient compliance and drug effectiveness. The objectives of this study were to develop film formulations and characterizations composed of tetrahydrocannabinol and taste-masking polymers and develop tetrahydrocannabinol-coated granules via a fluidized bed-coating. Eudragit E100 (E100) and Kollidon VA64 (KVA64) were used as taste-masking polymers. Plasticizers with different chemical structures, including polyethylene glycol (PEG-400), triacetin, and diethyl phthalate, were used to modify various film characteristics. …
Identification Of Carpaine In Carica Papaya Leaf Products Using Direct Analysis In Real Time Mass Spectrometry (Dart-Ms), Piyawadi Khaoiam
Identification Of Carpaine In Carica Papaya Leaf Products Using Direct Analysis In Real Time Mass Spectrometry (Dart-Ms), Piyawadi Khaoiam
Chulalongkorn University Theses and Dissertations (Chula ETD)
Carpaine, a major alkaloid present in Carica papaya leaves, has been shown to increase platelet counts in patients suffering from thrombocytopenia. Numerous commercial papaya leaf products are available, but few provide proper bioactive ingredient information. We present herein a technique for rapid screening of carpaine in these products using DART-MS. The results indicate that carpaine was detected in various forms (powder, solution) of papaya leaves. Its presence was confirmed by examining the mass pattern when conducted on a standard solution at both low and high voltages (+10 V and +90 V), using MS1 and MS2 data obtained from LC-QTOF-MS/MS. The …