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Accessing Vocational Education For Out-Of-School Myanmar Migrant Youths In Mae Sot, Thailand, Phyu Sin Maw Lin
Accessing Vocational Education For Out-Of-School Myanmar Migrant Youths In Mae Sot, Thailand, Phyu Sin Maw Lin
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis examined the accessibility of the Out-of-School Myanmar Migrant Youths to vocational education in the Mae Sot district, Thailand by employing the ‘4As framework’ for Education with the indicators of availability, accessibility, acceptability, and adaptability. In this thesis, out-of-school Myanmar migrant youths are understood as those who have left education without receiving formal qualifications, and who are under the age of 21. Myanmar migrant youth population in Thailand has been significantly growing due to the unrested conditions all around Myanmar. Among them, thousands of youths struggle to access any type of educational pathway because of their academic background, financial …
Bioactive Extracts Of The Roots Of Cannabis Sativa L. Against Dental Pathogens, Pattarapol Udomlarp
Bioactive Extracts Of The Roots Of Cannabis Sativa L. Against Dental Pathogens, Pattarapol Udomlarp
Chulalongkorn University Theses and Dissertations (Chula ETD)
The roots of Cannabis sativa L. are often underutilized and regarded as agricultural waste, despite reports of bioactive compounds with potential pharmaceutical applications. This study focused on developing an ecofriendly method for extracting triterpenoids and investigating the oral antimicrobial activity of cannabis root extracts. The primary objectives were to optimize an extraction process yielding high triterpenoid content and evaluate the potential of extracts to inhibit dental pathogens, thereby promoting the value of cannabis roots for future applications.The efficiency of Soxhlet solvent extraction, ultrasonic-assisted extraction (UAE), subcritical water extraction, and subcritical dimethyl ether extraction (SDMEE) was compared for yielding triterpenoids, particularly …
Affects Of Air: A More-Than-Human Study Of Atmospheres And Sustainable Development In Bang Kachao, Leonie Hueppe
Affects Of Air: A More-Than-Human Study Of Atmospheres And Sustainable Development In Bang Kachao, Leonie Hueppe
Chulalongkorn University Theses and Dissertations (Chula ETD)
This paper investigates urban air as an agentic force shaping the relationship between Bangkok and Bang Kachao, its designated "green lung." Traditional sustainable development frameworks often overlook air's dynamic role, treating it as a passive environmental component rather than an active participant in urban ecologies. Drawing on ethnographic research in Bang Kachao, this study argues that an affective, more-than-human analysis of urban air provides crucial insights for rethinking sustainable urban development beyond anthropocentric paradigms. Employing an urban assemblage approach and the concept of affective atmospheres, the paper explores how the materializations of urban air — specifically heat, wind, and pollution …
Reckoning Movement Parties: In-Depth Analysis Of Movement Engagement And Development Perspective From The Indonesian Labour Party, Margianta Surahman Juhanda
Reckoning Movement Parties: In-Depth Analysis Of Movement Engagement And Development Perspective From The Indonesian Labour Party, Margianta Surahman Juhanda
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study examines the Indonesian Labour Party (ILP) as a significant case study of movement parties in Southeast Asia's democratic landscape. The research investigates how the ILP, emerging from grassroots organizations and trade unions, navigates the complex relationship between social movements and formal political representation. Following recent changes in Indonesia's electoral threshold regulations, this study employs qualitative methodology, including in-depth interviews, to analyze the party's development trajectory and its engagement with social movements. Particular attention is paid to intergenerational dynamics within the party, examining how ideological perspectives and activism strategies differ between younger and older members. The research aims to …
Beyond The ‘Boy Crisis’: Reframing Gender Performativity In Belgian Classrooms, Marjolein Vanmaercke
Beyond The ‘Boy Crisis’: Reframing Gender Performativity In Belgian Classrooms, Marjolein Vanmaercke
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis challenges the dominant discourse surrounding the so-called "boy crisis" in education by critically examining gender performativity in Belgian classrooms. Rather than accepting the narrative that boys are inherently disadvantaged in contemporary schooling, this study interrogates how gender is constructed and performed within educational settings. Drawing on Judith Butler’s theory of performativity, the research explores how teachers, curricula, and peer interactions contribute to the reinforcement or subversion of traditional gender norms. Using qualitative methods, including classroom observations and interviews with educators and students, the study highlights the ways in which gendered expectations shape students' educational experiences and outcomes. The …
Queer Tourism Development In Nepal: Building Inclusive Tourism Through Rights-Based Approach, Kaushal Joshi
Queer Tourism Development In Nepal: Building Inclusive Tourism Through Rights-Based Approach, Kaushal Joshi
Chulalongkorn University Theses and Dissertations (Chula ETD)
Nepal has become a notable leader in South Asia regarding LGBTQIA+ rights, with legal reforms ranging from “third or other” gender citizenship rights to recognition of sexual and gender minority rights enshrined in the constitution, to the 2023 Supreme Court directive urging the legislature to recognize same-sex marriage. However, these advancements have not meaningfully reflected in the country’s tourism development strategies. This research addresses the disconnect between progressive legal recognition and the lack of inclusive LGBTQIA+ practices in Nepal’s tourism sector, proposing queer tourism as a an avenue for inclusion, empowerment, and sustainable development. Drawing from LGBT tourism theory and …
Sino-Thai Economic Cooperation Under Bri In The Eyes Of Taiwanese And Chinese Media: A Comparative Study From 2017 To 2024, Chun-Tsung Yang
Sino-Thai Economic Cooperation Under Bri In The Eyes Of Taiwanese And Chinese Media: A Comparative Study From 2017 To 2024, Chun-Tsung Yang
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study investigates how Chinese and Taiwanese media construct narratives around Sino-Thai economic cooperation, focusing on the Belt and Road Initiative (BRI). Through a comparative content analysis of 20 primary articles and 30 supplementary articles from People's Daily Online, The Paper, United Daily News (UDN), and Central News Agency (CNA), the research explores differences in thematic focus, narrative frames, sentiment tone, source attribution, and visual representation. Findings reveal that Chinese state media consistently employ centralized, development-focused frames with minimal dissent. In contrast, Taiwanese media, particularly CNA, offer more pluralistic and skeptical coverage, especially regarding Thai social responses to Sino-Thai economic …
Japanese Public-Private Partnerships For Promoting Sustainable Development: An Analysis Of Jica's Sdgs-Oriented Business Support In Thailand, Kana Tsutsumi
Chulalongkorn University Theses and Dissertations (Chula ETD)
The Sustainable Development Goals (SDGs) recognize the private sector as a crucial driver for global sustainable development. To align with the SDGs, Japan has strengthened public-private partnerships (PPPs) in its ODA. This thesis explores how the Japan International Cooperation Agency’s (JICA) SDGs Business Supporting Survey promotes sustainable development for both Japan and Thailand. This survey scheme aims to encourage Japanese SMEs to test socially impactful business models. This study uses two case studies of Japanese SMEs in Thailand through document analysis and interviews to examine how PPPs facilitate technology transfer, local access, and network building. Even though there are still …
Beyond The 'Grand Line': One Piece’S Radical Reimagining Of Global Politics, Titipong Mahattanasin
Beyond The 'Grand Line': One Piece’S Radical Reimagining Of Global Politics, Titipong Mahattanasin
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis explores how the long-running Japanese manga One Piece functions as a radical political archive that reflects, critiques, and reimagines global politics across three historical eras. Drawing from the fields of International Relations and Development Studies, this research analyzes how the manga stages fictional yet deeply resonant struggles over power, freedom, and justice. Through close readings of key narrative arcs—Alabasta, Skypiea, Enies Lobby, Marineford, Dressrosa, and Wano—this study situates One Piece within real-world political contexts including post–Cold War liberal triumphalism, the global War on Terror, and the protest movements of the 2010s. The thesis draws upon theoretical insights from …
Health System Resilience In Karenni/ Kayah State: Exploring The Role Of Local Interim Health Services, Khin Sabai Aung
Health System Resilience In Karenni/ Kayah State: Exploring The Role Of Local Interim Health Services, Khin Sabai Aung
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis examines health system resilience in Karenni (Kayah) State, Myanmar, by analyzing how local interim health services sustain care delivery, adapt to conflict, and ensure continuity within a fragile and liminal governance context. Guided by the Health System Resilience (HSR) framework, the study draws on semi-structured interviews with doctors, midwives, and a representative from the Karenni Interim Executive Council (IEC). Findings reveal that Karenni’s health system demonstrates absorptive, adaptive, and emerging transformative capacities. These capacities are primarily driven by morally committed individuals and grassroots collectives operating in the aftermath of state collapse. Rather than functioning in isolation, the health …
Socioeconomic Endurance During The Post-Coup Conflict: A Case Study Of A Community In Mandalay Region, Central Myanmar, Htet Yamone Win
Socioeconomic Endurance During The Post-Coup Conflict: A Case Study Of A Community In Mandalay Region, Central Myanmar, Htet Yamone Win
Chulalongkorn University Theses and Dissertations (Chula ETD)
Myanmar’s post-coup context has severely affected the local communities through the ongoing multiple crises in governance, livelihoods, and security matters. Myanmar military’s attempt to coup in 2021 triggered widespread resistance, including both non-violence and armed-resistance strategies, and led to sharp economic decline and public service disruptions. Those crises have been reshaping everyone’s daily life in Myanmar. While the much of existing literature focuses on those who have fled the country, this study centers on the experiences of individuals and communities who remain in the country, embracing the direct impact of political repression, economic instability and social fragmentation. Focusing on a …
Enhancing Resilience Through Public Policy: Lessons From Disaster Logistics In The Post-2011 Tohoku Earthquake In Sendai City, Megumi Okumura
Enhancing Resilience Through Public Policy: Lessons From Disaster Logistics In The Post-2011 Tohoku Earthquake In Sendai City, Megumi Okumura
Chulalongkorn University Theses and Dissertations (Chula ETD)
In recent years, the integration of resilience into disaster policy has gained global traction. Despite being widely adopted as a concept by international institutions such as the United Nations Office for Disaster Risk Reduction (UNDRR) and the World Bank, resilience often remains underdeveloped at the operational level and is frequently seen as a “buzzword.” Even in Japan, although recognized for its disaster preparedness, there has been limited debate on how resilience is integrated in public policy. The 2011 Tohoku Earthquake prompted fundamental questions such as “Resilience to what?” and “Resilience for whom?”, highlighting the need to examine the purpose and …
Gemstone Identification By Raman Spectroscopy Combined With Chemometric Methods, Nontawat Sricharoen
Gemstone Identification By Raman Spectroscopy Combined With Chemometric Methods, Nontawat Sricharoen
Chulalongkorn University Theses and Dissertations (Chula ETD)
Accurate and reliable gemstone classification is critical in gemology for authentication and identification purposes. A one-class classifier using self-organizing maps (SOMs), combined with Monte Carlo permutation testing, was successfully developed for gemstone classification based on Raman spectroscopy data. The developed SOM model was optimized by adjusting the map size and training iteration counts, and Monte Carlo permutation tests were conducted to evaluate prediction score through empirical p-values by generating random permutations of the data, allowing for a statistically robust assessment of classification reliability. Using the Raman spectra of RRUFF database and certain garnet gemstones, the model demonstrated high classification accuracy …
Enhance Gnn-Based Social Recommendation Using User Dynamic Characteristics, Janekhwan Kitsupapaisan
Enhance Gnn-Based Social Recommendation Using User Dynamic Characteristics, Janekhwan Kitsupapaisan
Chulalongkorn University Theses and Dissertations (Chula ETD)
In recent developments, social recommendation frameworks have increasingly employed Graph Neural Networks (GNNs) to model social connections among users, encompassing both immediate and more distant relationships within the network. Nonetheless, current advanced models encounter challenges related to the limited number of propagation steps they can perform on the graph. Messages originating from distant nodes often diminish the distinct features of the target user, resulting in more homogeneous representations that are difficult to differentiate. This issue is known as over-smoothing. Several approaches have been proposed to address this, aiming to preserve individual user traits by incorporating auxiliary information into GNN-based models. …
Relationship Between Hotspot And Geography – Meteorology Factors In Thailand And Neighboring Countries, Thanchanok Ngernted
Relationship Between Hotspot And Geography – Meteorology Factors In Thailand And Neighboring Countries, Thanchanok Ngernted
Chulalongkorn University Theses and Dissertations (Chula ETD)
Air pollution is a critical issue in many countries and has become a significant problem in Southeast Asia. Wildfires, agricultural burning, and biomass burning are major sources of pollution emissions. This study aims to analyze hotspot activity and study the relationship between hotspots and geographic-meteorological factors in Thailand and neighboring countries. MODIS hotspot data were analyzed using the frequency-magnitude distribution (FMD) and geography-meteorology factors. The results indicate that areas with high hotspot activity were mainly found in northwestern to eastern Cambodia and northern Laos. Additionally, northern Laos and some pockets in Myanmar showed high hotspot intensity, capable of generating a …
Probiotics-Encapsulated Hydrogel Beadsfor Functional Food Applications, Korlid Thinkohkaew
Probiotics-Encapsulated Hydrogel Beadsfor Functional Food Applications, Korlid Thinkohkaew
Chulalongkorn University Theses and Dissertations (Chula ETD)
The growing application of probiotics in functional food products has highlighted the need to preserve their viability and stability throughout gastrointestinal transit and storage. This study aims to address these issues by developing and optimizing biopolymer-based hydrogel beads using a vibrational nozzle-assisted ionic gelation method. Initially, probiotics were encapsulated in chitosan-coated alginate/gellan gum microcapsules using a vibrational nozzle-assisted ionic gelation method. The encapsulation process was optimized via response surface methodology, achieving high encapsulation efficiency (97.35%) under optimal conditions (0.6% gellan gum, 1.61% CaCl2, and a flow rate of 9.84 mL/min). The optimized microcapsules demonstrated strong tolerance to simulated gastric fluid …
Environmental Reconstruction In Nong Thale Pron, Nakhon Si Thammarat Province, Kanokpon Surijamorn
Environmental Reconstruction In Nong Thale Pron, Nakhon Si Thammarat Province, Kanokpon Surijamorn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Climate change is one of the major factors influencing environmental changes. The study of proxies from geological records can extend climate data into the past, enabling the reconstruction of past environmental changes. This study collected sediment cores from three points at the deepest part of Nong Thale Pron, Nakhon Si Thammarat Province. The sediment core NTP-CP6 was selected for analysis using X-ray fluorescence (XRF), radiocarbon dating, grain size analysis, total organic carbon, total nitrogen, stable carbon isotopes, and n-alkanes. During the Last Glacial Maximum (21–19 ka BP), dry conditions were caused by a strong northeast monsoon and the exposure of …
Computational Fluid Dynamics And Artificial Neural Network Based Modeling Of Microplastics Seperation Using Hydrocyclone, Dulyapat Thiemsakul
Computational Fluid Dynamics And Artificial Neural Network Based Modeling Of Microplastics Seperation Using Hydrocyclone, Dulyapat Thiemsakul
Chulalongkorn University Theses and Dissertations (Chula ETD)
Microplastics represent a considerable environmental hazard, particularly to aquatic ecosystems. These particles can adversely impact marine organisms and infiltrate the food chain, potentially posing risks to human health. Due to their small size and ubiquitous distribution, the removal of microplastics from water presents a significant technical challenge. This study focuses on the separation of microplastics using hydrocyclones. A three-dimensional Eulerian–Eulerian computational fluid dynamics (CFD) model was used to investigate this process. The model showed strong agreement with experimental data in terms of pressure drop, water split, and axial velocity, confirming the reliability of the simulation results. In this work, design …
Debris Flow And Flood Susceptibility Assessment In Phang-Nga Province, Southern Thailand, Aksara Kulsilarak
Debris Flow And Flood Susceptibility Assessment In Phang-Nga Province, Southern Thailand, Aksara Kulsilarak
Chulalongkorn University Theses and Dissertations (Chula ETD)
Phang-nga, a province in Southern Thailand, is highly susceptible to geohazards such as debris flows and flooding, both of which pose significant risks to human life and property. Two major topographic factors contribute to the potential for debris flow: i) steep mountain slopes and ii) the presence of multiple mountain-front outlets. This study presents the creation of susceptibility maps for debris flow and flood hazards in Phang-nga, using the Frequency Ratio (FR) method. The analysis classified the region into five susceptibility levels: very low, low, moderate, high, and very high, based on natural break classification. For debris flow, moderate susceptibility …
Nanofluid Flow Behavior And Heat Exchange In Polymer Based Microchannel Heat Exchanger Using Computational Fluid Dynamics And Fluid-Structure Interaction, Chaiyanan Kamsuwan
Nanofluid Flow Behavior And Heat Exchange In Polymer Based Microchannel Heat Exchanger Using Computational Fluid Dynamics And Fluid-Structure Interaction, Chaiyanan Kamsuwan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Energy is the main factor that driving human society for century, but rapid growth of population tends to raise world energy demand. Many researchers suggest many ideas such as using new energy resources and alternative energies. However, an interested alternative is to utilize waste heat from flue gas. To utilize energy embedded in the flue gas, two challenges remaining include their low heat potential in 100 – 200 oC and corrosion risk in the equipment due to corrosive gas such as CO2 and H2S. To encounter the challenges polymer-based microchannel heat exchanger (PMHE) was developed for reutilizing waste heat in …
Dft Study Of H2 Adsorption On Graphitic Carbon Nitride Nanomaterials Decorated With Selected Elements, Kanthira Kaewsud
Dft Study Of H2 Adsorption On Graphitic Carbon Nitride Nanomaterials Decorated With Selected Elements, Kanthira Kaewsud
Chulalongkorn University Theses and Dissertations (Chula ETD)
In this work, the hydrogen adsorption capabilities of graphitic carbon nitride (g-C3N4) nanomaterials in nanotube and nanosheet forms, decorated with selected elements from period 3 (Al, Si, P, and S) and period 4 (Ga, Ge, As, and Se), were investigated using periodic density functional theory (DFT) at the PBEPBE/6-31G(d) level. The results demonstrate that elemental decoration significantly enhances the hydrogen adsorption performance of both structural configurations. Among the heptazine-based nanotubes (hg−C3N4−NTs), the S-decorated (4,0) hg−C3N4−NT exhibited the most favorable physisorption, with an adsorption energy of −1.34 eV, while Al-decorated (5,0) and (6,0) hg−C3N4−NTs demonstrated strong chemisorption energies of −1.28 eV. …
Alkyl Levulinate Synthesis From Sugar And Agricultural Waste Using Acidic Heterogeneous Catalysts, Songkeid Kaewmuangphet
Alkyl Levulinate Synthesis From Sugar And Agricultural Waste Using Acidic Heterogeneous Catalysts, Songkeid Kaewmuangphet
Chulalongkorn University Theses and Dissertations (Chula ETD)
The novel combination of strong Brønsted acidity (B) from propyl sulfonic acid functionalized on H-Y zeolite (HY-PrSO3H) and a series of Lewis acidic (L) catalysts (SnO2, ZrO2, Cr2O3) demonstrated high potential as a catalyst for alkyl levulinate (AL) production from glucose, fructose, sucrose, cellulose, and empty palm fruit bunch (EFB) as agricultural waste. Unmodified zeolite was insufficient to provide the required Brønsted and Lewis acid sites necessary for enhancing AL yield. The catalytic solvothermal process was evaluated by studying the effects of various parameters on AL yield. The optimal catalyst for AL formation was achieved by combining the Faujasite (FAU) …
Dementia Detection Using Transfer Learning From Recorded Speech, Gun Wirojburapa
Dementia Detection Using Transfer Learning From Recorded Speech, Gun Wirojburapa
Chulalongkorn University Theses and Dissertations (Chula ETD)
Dementia is an irreversible and progressive condition that affects cognitive impairment, and millions of people are affected. Early detection provides patients with premature treatment and improves their quality of life. Traditional methods for dementia detection, such as cognitive assessment and neurological analysis, are expensive and time-consuming. Therefore, this thesis aims to research alternative methods to detect dementia, such as speech analysis. This thesis performs dementia classification by using transfer learning and machine learning techniques. Samples in the dataset consist of English and Chinese speakers. This study found transfer learning and machine learning techniques able to classify the speakers between dementia …
Spatio-Heterogeneity Risk Assessment From Microplastic Contaminations In Water And Sediment Of The Inner Gulf Of Thailand, Sarayut Suanluang
Spatio-Heterogeneity Risk Assessment From Microplastic Contaminations In Water And Sediment Of The Inner Gulf Of Thailand, Sarayut Suanluang
Chulalongkorn University Theses and Dissertations (Chula ETD)
The inner Gulf of Thailand, a shallow semi-enclosed marine basin, plays a vital economic and ecological role for Thailand, yet faces increasing threats from microplastic (MP) pollution driven by urbanization, industrial and agriculture developments, and riverine discharges. This study aimed to assess the spatial and vertical distributions, polymer characteristics, and ecological risks associated with MP contamination in water columns and surface sediments throughout the inner Gulf. Sampling was conducted at 13 stations, with water collected from surface, mid-depth, and bottom layers, and sediment samples taken from corresponding surface sediments. MPs were analyzed for abundance, size, shape, color, and polymer composition …
Rupert Property Of Some Solids In Higher Dimensions, Pongbunthit Tonpho
Rupert Property Of Some Solids In Higher Dimensions, Pongbunthit Tonpho
Chulalongkorn University Theses and Dissertations (Chula ETD)
We say that a solidS has the Rupert property if a hole could be cut into one copy of S so that another copy of S can be passed through this hole. In recent years, many solids in R$ have been shown to have the Rupert property. However, not much is known about the Rupert property in higher dimensions. This dissertation investigates the Rupert property for some solids in R". We introduce lemmas that help to verify this property. In particular, we prove that some particular n-simplices, the generalized n-octahedrons/and the two-way cones in In have the Rupert property.
Induced Thermotolerance In Metarhizium Spp. Using Gamma Irradiation And Mass Spore Production Using Various Substrates To Control Brown Planthopper Nilaparvata Lugens (Stål), Suleiman Abba Muazu
Induced Thermotolerance In Metarhizium Spp. Using Gamma Irradiation And Mass Spore Production Using Various Substrates To Control Brown Planthopper Nilaparvata Lugens (Stål), Suleiman Abba Muazu
Chulalongkorn University Theses and Dissertations (Chula ETD)
The brown planthopper (BPH), Nilaparvata lugens (Stål), is a major rice pest in Southeast Asia and is developing increased resistance to chemical insecticides. Fungi from the genus Metarhizium offers a promising alternative for biological control, but their efficacy is constrained by slow infectivity and environmental sensitivity. In this study, two Metarhizium isolates, MLUBN038 and MNMHN031, were identified as M. koreanum by multilocus phylogenetic analysis. Improving thermotolerance of the fungus using gamma irradiation generated 79 thermotolerant mutants. Among them, ML038-Mt 71 and MN031-Mt 46 showed improved vegetative heat tolerance at 39 °C and conidial resistance at 45 °C, along with enhanced …
Effects Of Ratio Of Titanium Dioxide To Alumina And Plasticizer On Hiding Power And Flexibility Of Pad Printing Ink Film Applied On Fabric, Pathompong Pangamol
Effects Of Ratio Of Titanium Dioxide To Alumina And Plasticizer On Hiding Power And Flexibility Of Pad Printing Ink Film Applied On Fabric, Pathompong Pangamol
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study explores the formulation, characterization, and printability of prototype inks based on TPX and TPSP polymer matrices, with a focus on the effects of pigment composition, viscosity, and flexibility modifiers. FT-IR and XRF analyses confirmed that both ink types primarily contained titanium dioxide (TiO₂) and aluminum oxide (Al₂O₃), indicating the use of similar pigments. The results revealed that ink viscosity significantly influenced printability. TPX-based inks exhibited high viscosity, resulting in poor ink transfer and failed printing, while TPSP-based inks demonstrated lower viscosity and better print performance. However, both ink types showed limited opacity, even after multiple print layers. Microscopic …
Neuroprotective Effect Of Phenolic Compounds From Thai Plants, Panuwat Worasrihirun
Neuroprotective Effect Of Phenolic Compounds From Thai Plants, Panuwat Worasrihirun
Chulalongkorn University Theses and Dissertations (Chula ETD)
Neurodegeneration is a progressive condition characterized by the loss of neurons and synaptic connections, with the risk of diseases like Alzheimer's and Parkinson's increasing with age due to factors such as protein misfolding, oxidative stress, and neuroinflammation, which disrupt cognitive and motor functions. Despite significant research, effective treatments for age-related neurodegeneration remain limited. This study explores the neuroprotective effects of phenolic compounds from Thai plants, known for their antioxidant properties. Phenolic compounds were extracted from Boesenbergia rotunda (L.), Limnophila aromatica, and Acronychia pedunculata (L.), along with a library of at least 50 compounds. Their cytotoxicity was assessed in SH-SY5Y neuroblastoma …
Osteoporosis In Androgen Deficient Rats And Monkeys And Preventive Effects Of Pueraria Mirifica On Bone Loss, Thaweechai Saetae
Osteoporosis In Androgen Deficient Rats And Monkeys And Preventive Effects Of Pueraria Mirifica On Bone Loss, Thaweechai Saetae
Chulalongkorn University Theses and Dissertations (Chula ETD)
Androgen deficiency is a common cause of bone loss in males. However, determining the exact timing of significant declines in androgen levels and the associated bone loss during this period is challenging. To understand this phenomenon, the first set of experiments was conducted in male rats to observe changes in bone following both a gradual and abrupt decline in testosterone levels. Four-month-old male rats were sham-operated (SH) and orchidectomized (ODX). After 9 days, 2, 4, 6, and 8 months, the rats were euthanized, and bone quantity (mass) and quality (geometry) were measured at the 4th lumbar vertebra (L4), tibia metaphysis …
Biological Fluorescence Sensor Derived From Naphthalimide-Functionalized Pillar[5]Arene, Yanisa Sanguansap
Biological Fluorescence Sensor Derived From Naphthalimide-Functionalized Pillar[5]Arene, Yanisa Sanguansap
Chulalongkorn University Theses and Dissertations (Chula ETD)
Lung cancer has unavoidably encountered the most substantial fatality rate in recent years worldwide. The development of efficient and accessible diagnostic methods is required to assess disease severity. Prior studies have discovered the highest levels of long-chain aldehyde compounds particularly octanal (C8), nonanal (C9), and L-glutathione (L-GSH) as potential biomarkers for lung cancer. Herein, the novel artificial fluorescence sensor HNP5A containing bis-hydrazine naphthalimide decorated pillar[5]arene and 1,2-bis(6-bromohexyl)disulfane (BS) containing a disulfide part linked to a terminal bromoalkane were designed for two conceptual approaches. The first concept, sensor HNP5A has been accomplished for sensitive and selective detection of long-chain aldehydes. This …